Search of human proteins with 21328446

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21328446 hormone-sensitive lipase [Homo sapiens]
         (1076 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21328446 hormone-sensitive lipase [Homo sapiens]                  2140   0.0  
gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens]           63   1e-09
gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo sap...    62   4e-09
gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo sa...    59   3e-08
gi|13129104 coiled-coil domain containing 86 [Homo sapiens]            59   3e-08
gi|68299767 arylacetamide deacetylase [Homo sapiens]                   56   2e-07
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       56   2e-07
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    56   2e-07
gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ...    54   8e-07
gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ...    54   8e-07
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ...    54   8e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          53   1e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          53   1e-06
gi|157041239 arylacetamide deacetylase-like 3 isoform 1 [Homo sa...    52   3e-06
gi|157041237 arylacetamide deacetylase-like 3 isoform 2 [Homo sa...    52   3e-06
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       52   4e-06
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       52   4e-06
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    51   7e-06
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H...    51   7e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    50   9e-06
gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo...    49   2e-05
gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo ...    49   2e-05
gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo ...    49   2e-05
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    49   2e-05
gi|54860079 nadrin isoform 1 [Homo sapiens]                            49   2e-05
gi|54860105 nadrin isoform 2 [Homo sapiens]                            49   2e-05
gi|41281612 zinc finger protein 828 [Homo sapiens]                     49   3e-05
gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ...    49   3e-05
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [...    49   3e-05
gi|226423952 arylacetamide deacetylase-like 1 isoform c [Homo sa...    49   3e-05

>gi|21328446 hormone-sensitive lipase [Homo sapiens]
          Length = 1076

 Score = 2140 bits (5544), Expect = 0.0
 Identities = 1076/1076 (100%), Positives = 1076/1076 (100%)

Query: 1    MEPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQ 60
            MEPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQ
Sbjct: 1    MEPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQ 60

Query: 61   QETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLG 120
            QETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLG
Sbjct: 61   QETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLG 120

Query: 121  KESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQET 180
            KESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQET
Sbjct: 121  KESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQET 180

Query: 181  PEQSDKQTTPVQGAKSKQGSLTELGFLTKLQELSIQRSALEWKALSEWVTDSESESDVGS 240
            PEQSDKQTTPVQGAKSKQGSLTELGFLTKLQELSIQRSALEWKALSEWVTDSESESDVGS
Sbjct: 181  PEQSDKQTTPVQGAKSKQGSLTELGFLTKLQELSIQRSALEWKALSEWVTDSESESDVGS 240

Query: 241  SSDTDSPATMGGMVAQGVKLGFKGKSGYKVMSGYSGTSPHEKTSARNHRHYQDTASRLIH 300
            SSDTDSPATMGGMVAQGVKLGFKGKSGYKVMSGYSGTSPHEKTSARNHRHYQDTASRLIH
Sbjct: 241  SSDTDSPATMGGMVAQGVKLGFKGKSGYKVMSGYSGTSPHEKTSARNHRHYQDTASRLIH 300

Query: 301  NMDLRTMTQSLVTLAEDNIAFFSSQGPGETAQRLSGVFAGVREQALGLEPALGRLLGVAH 360
            NMDLRTMTQSLVTLAEDNIAFFSSQGPGETAQRLSGVFAGVREQALGLEPALGRLLGVAH
Sbjct: 301  NMDLRTMTQSLVTLAEDNIAFFSSQGPGETAQRLSGVFAGVREQALGLEPALGRLLGVAH 360

Query: 361  LFDLDPETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALT 420
            LFDLDPETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALT
Sbjct: 361  LFDLDPETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALT 420

Query: 421  QLRALVYYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGFQFTPAIRP 480
            QLRALVYYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGFQFTPAIRP
Sbjct: 421  QLRALVYYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGFQFTPAIRP 480

Query: 481  FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGAEFERITQNLDVHFWK 540
            FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGAEFERITQNLDVHFWK
Sbjct: 481  FLQTISIGLVSFGEHYKRNETGLSVAASSLFTSGRFAIDPELRGAEFERITQNLDVHFWK 540

Query: 541  AFWNITEMEVLSSLANMASATVRVSRLLSLPPEAFEMPLTADPTLTVTISPPLAHTGPGP 600
            AFWNITEMEVLSSLANMASATVRVSRLLSLPPEAFEMPLTADPTLTVTISPPLAHTGPGP
Sbjct: 541  AFWNITEMEVLSSLANMASATVRVSRLLSLPPEAFEMPLTADPTLTVTISPPLAHTGPGP 600

Query: 601  VLVRLISYDLREGQDSEELSSLIKSNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQTS 660
            VLVRLISYDLREGQDSEELSSLIKSNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQTS
Sbjct: 601  VLVRLISYDLREGQDSEELSSLIKSNGQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQTS 660

Query: 661  RSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCALLGSTGERIC 720
            RSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCALLGSTGERIC
Sbjct: 661  RSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCALLGSTGERIC 720

Query: 721  LAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATMLQPAASPSRLLSLMDPLLPLSVL 780
            LAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATMLQPAASPSRLLSLMDPLLPLSVL
Sbjct: 721  LAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATMLQPAASPSRLLSLMDPLLPLSVL 780

Query: 781  SKCVSAYAGAKTEDHSNSDQKALGMMGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQ 840
            SKCVSAYAGAKTEDHSNSDQKALGMMGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQ
Sbjct: 781  SKCVSAYAGAKTEDHSNSDQKALGMMGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQ 840

Query: 841  KMSEPIAEPMRRSVSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSETSSDTPEMSLSAET 900
            KMSEPIAEPMRRSVSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSETSSDTPEMSLSAET
Sbjct: 841  KMSEPIAEPMRRSVSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSETSSDTPEMSLSAET 900

Query: 901  LSPSTPSDVNFLLPPEDAGEEAEAKNELSPMDRGLGVRAAFPEGFHPRRSSQGATQMPLY 960
            LSPSTPSDVNFLLPPEDAGEEAEAKNELSPMDRGLGVRAAFPEGFHPRRSSQGATQMPLY
Sbjct: 901  LSPSTPSDVNFLLPPEDAGEEAEAKNELSPMDRGLGVRAAFPEGFHPRRSSQGATQMPLY 960

Query: 961  SSPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVE 1020
            SSPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVE
Sbjct: 961  SSPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVE 1020

Query: 1021 DLPHGFLTLAALCRETRQAAELCVERIRLVLTPPAGAGPSGETGAAGVDGGCGGRH 1076
            DLPHGFLTLAALCRETRQAAELCVERIRLVLTPPAGAGPSGETGAAGVDGGCGGRH
Sbjct: 1021 DLPHGFLTLAALCRETRQAAELCVERIRLVLTPPAGAGPSGETGAAGVDGGCGGRH 1076


>gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens]
          Length = 401

 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 49/160 (30%), Positives = 74/160 (46%), Gaps = 9/160 (5%)

Query: 635 PRPQQAPRSRSLIVHFHGGGFVAQTSRSHE-PYLKSW-AQELGAPIISIDYSLAPEAPFP 692
           P+ +   R R+ +++FHGGGF   +S+     +L  W A  L A ++ +DY LAP+  FP
Sbjct: 96  PKRKSETRRRA-VIYFHGGGFCFGSSKQRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFP 154

Query: 693 RALEECFFAYCWAI--KHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGI- 749
              E+   A  + +  K     G    RIC+AGDS+GGNL  T   +       +   I 
Sbjct: 155 AQFEDGLAAVKFFLLEKILTKYGVDPTRICIAGDSSGGNLA-TAVTQQVQNDAEIKHKIK 213

Query: 750 --MAAYPATMLQPAASPSRLLSLMDPLLPLSVLSKCVSAY 787
             +  YP   +  +  PS   +    +L   V  K VS Y
Sbjct: 214 MQVLLYPGLQITDSYLPSHRENEHGIVLTRDVAIKLVSLY 253



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 29/69 (42%), Positives = 40/69 (57%)

Query: 960  YSSPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVV 1019
            YS P + +    PLLA DS L++LP  +I+ C  D + DD +M   RLRN+G  V    +
Sbjct: 307  YSLPGLTDSRALPLLANDSQLQNLPLTYILTCQHDLLRDDGLMYVTRLRNVGVQVVHEHI 366

Query: 1020 EDLPHGFLT 1028
            ED  HG L+
Sbjct: 367  EDGIHGALS 375


>gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo
           sapiens]
          Length = 440

 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 50/161 (31%), Positives = 78/161 (48%), Gaps = 22/161 (13%)

Query: 635 PRPQQAPRSRSLIVHFHGGGFVAQTS--RSHEPYLKSWAQELGAPIISIDYSLAPEAPFP 692
           P+P++ P  RS +V+ HGGG+   ++  R ++    + A+EL A I+SI+Y L P+  FP
Sbjct: 131 PKPEE-PLKRS-VVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFP 188

Query: 693 RALEECFFAYCWAIKHCALLGSTGE--RICLAGDSAGGNLCFTVALRAAAYGVRVPDGI- 749
             + +   A  + +K   L     +  RIC++GDSAGGNL       AAA G +      
Sbjct: 189 EQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNL-------AAALGQQFTQDAS 241

Query: 750 --------MAAYPATMLQPAASPSRLLSLMDPLLPLSVLSK 782
                      YP        +PS   ++  P+LP  V+ K
Sbjct: 242 LKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVK 282



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 1/87 (1%)

Query: 939  AAFPEGFHPRRSSQGATQMPLYSSPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLD 998
            A+F + + P   + G  ++ +   P + +   +PL+A  ++L+ LP  +I+ C  D + D
Sbjct: 326  ASFTKNYKPVVQTTGNARI-VQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRD 384

Query: 999  DSVMLARRLRNLGQPVTLRVVEDLPHG 1025
            D +M A+RL + G  VTL   ED  HG
Sbjct: 385  DGIMYAKRLESAGVEVTLDHFEDGFHG 411


>gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo
           sapiens]
          Length = 448

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 50/169 (29%), Positives = 78/169 (46%), Gaps = 30/169 (17%)

Query: 635 PRPQQAPRSRSLIVHFHGGGFVAQTS----------RSHEPYLKSWAQELGAPIISIDYS 684
           P+P++ P  RS +V+ HGGG+   ++          R ++    + A+EL A I+SI+Y 
Sbjct: 131 PKPEE-PLKRS-VVYIHGGGWALASASASWSPSDEIRYYDELCTAMAEELNAVIVSIEYR 188

Query: 685 LAPEAPFPRALEECFFAYCWAIKHCALLGSTGE--RICLAGDSAGGNLCFTVALRAAAYG 742
           L P+  FP  + +   A  + +K   L     +  RIC++GDSAGGNL       AAA G
Sbjct: 189 LVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNL-------AAALG 241

Query: 743 VRVPDGI---------MAAYPATMLQPAASPSRLLSLMDPLLPLSVLSK 782
            +                 YP        +PS   ++  P+LP  V+ K
Sbjct: 242 QQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVK 290



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 1/87 (1%)

Query: 939  AAFPEGFHPRRSSQGATQMPLYSSPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLD 998
            A+F + + P   + G  ++ +   P + +   +PL+A  ++L+ LP  +I+ C  D + D
Sbjct: 334  ASFTKNYKPVVQTTGNARI-VQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRD 392

Query: 999  DSVMLARRLRNLGQPVTLRVVEDLPHG 1025
            D +M A+RL + G  VTL   ED  HG
Sbjct: 393  DGIMYAKRLESAGVEVTLDHFEDGFHG 419


>gi|13129104 coiled-coil domain containing 86 [Homo sapiens]
          Length = 360

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 57/222 (25%), Positives = 88/222 (39%), Gaps = 18/222 (8%)

Query: 15  PEPHQRPITPLEPGPEKTPIAQPES--KTLQGSNTQQKPASNQRPLTQQETPAQHDAESQ 72
           PE  + P +P  P  ++  +  PE   KT  GS   Q+ A  + P  Q E  A   A  Q
Sbjct: 39  PEETREPGSP--PSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGA---ASPQ 93

Query: 73  KEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALR 132
           ++     +S  ++   +P+ P  Q  P  +    +Q +          KE +T   P   
Sbjct: 94  RQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAP--- 150

Query: 133 QRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQ 192
            +H   P PG  EP P QQ     P+        R P +P        P  + +  T   
Sbjct: 151 -QHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGF 209

Query: 193 GAKSKQGSLTELGFLTKL--QELSI-----QRSALEWKALSE 227
           GAK ++GS ++     KL  +EL +      +S   WK  S+
Sbjct: 210 GAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSK 251


>gi|68299767 arylacetamide deacetylase [Homo sapiens]
          Length = 399

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 36/92 (39%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 647 IVHFHGGGF-VAQTSRSHEPYLKSW-AQELGAPIISIDYSLAPEAPFPRALEECFFAYCW 704
           + + HGGG+ V   + S    L  W A  L A ++S +Y LAP+  FP   E+ + A  W
Sbjct: 107 LFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRW 166

Query: 705 AI--KHCALLGSTGERICLAGDSAGGNLCFTV 734
            +  K  A  G   ERI ++GDSAGGNL   V
Sbjct: 167 FLRKKVLAKYGVNPERIGISGDSAGGNLAAAV 198



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 26/62 (41%), Positives = 35/62 (56%)

Query: 971  SPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHGFLTLA 1030
            +PLLA D+ L+ LP  +++ C  D + DD +M   RLRN G  VT   VED  HG  +  
Sbjct: 320  APLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNHVEDGFHGAFSFL 379

Query: 1031 AL 1032
             L
Sbjct: 380  GL 381


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 51/194 (26%), Positives = 86/194 (44%), Gaps = 27/194 (13%)

Query: 26  EPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQ---------KEPR 76
           EP  ++TP A+  S   + ++ ++  A  Q PL ++ T  +  AE Q          E  
Sbjct: 481 EPPADETP-AEARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETP 539

Query: 77  AQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQ--- 133
           A+ +S   EE  A + PA  QSP  + V +  +EA  +  P  G+E+  ++  A  Q   
Sbjct: 540 AEAQSPLSEETSAEEAPAEVQSPSAKGVSI--EEAPLELQPPSGEETTAEEASAAIQLLA 597

Query: 134 --RHVAQPGPGPGEPPPAQQE--------AESTPAAQAKPGAKREPSAPTESTSQETPEQ 183
                A+  P   +PPPA++         AE  PA    P A+  P+      ++E P  
Sbjct: 598 ATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAP-- 655

Query: 184 SDKQTTPVQGAKSK 197
           ++ Q  P + A ++
Sbjct: 656 AEVQPPPAEEAPAE 669



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 14/169 (8%)

Query: 22  ITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQ----QETPAQHDAESQKEPRA 77
           +  +E   ++TP A+ +S   + ++ ++ PA  Q P  +    +E P +    S +E  A
Sbjct: 528 LAAIEAPADETP-AEAQSPLSEETSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTA 586

Query: 78  QQKSASQE-----EFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALR 132
           ++ SA+ +     E  A + PA  Q P  +      Q   +++ P   +    ++ PA  
Sbjct: 587 EEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEV 646

Query: 133 QRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETP 181
           Q   A+  P   +PPP    AE  PA    P A+  P+      ++ETP
Sbjct: 647 QPPPAEEAPAEVQPPP----AEEAPAEVQPPPAEEAPAEVQSLPAEETP 691



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 55/281 (19%), Positives = 114/281 (40%), Gaps = 37/281 (13%)

Query: 2   EPGSKSVSRSDWQPEPHQRPITPLEPG----------PEKTPIAQPESKTLQGSNTQQKP 51
           E G K++SR+ +  E  + P   LE             E + + +  S  ++  +T++ P
Sbjct: 207 EIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFP 266

Query: 52  ASNQRPLTQQ-----------ETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPY 100
           A  Q PL ++           ET  Q    +++ P A+  +A  E  +  Q P  +++P 
Sbjct: 267 AKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPL 326

Query: 101 IQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQ 160
           ++     Q  +A ++ P +  E + +  P   +   ++  P    PPPA++        +
Sbjct: 327 VEFPAEIQPPSA-EESPSV--ELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGE 383

Query: 161 AK-PGAKREP----SAPTESTSQETPEQSDKQTT--------PVQGAKSKQGSLTELGFL 207
            + P A++ P      P E   +E P + +  T         P+   ++ +    EL   
Sbjct: 384 IRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLS 443

Query: 208 TKLQELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPA 248
           T ++  + +        L +  T  E+ +++   + T+ PA
Sbjct: 444 TAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPA 484



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 39/157 (24%), Positives = 70/157 (44%), Gaps = 9/157 (5%)

Query: 11  SDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAE 70
           +D  P   Q P++  E   E+ P A+ +S + +G + ++ P   Q P  ++ T  +  A 
Sbjct: 535 ADETPAEAQSPLSE-ETSAEEAP-AEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAA 592

Query: 71  SQ----KEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQ 126
            Q     E  A++  A  +   A + PA  Q P  +      Q   +++ P   +    +
Sbjct: 593 IQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE 652

Query: 127 QEPALRQRHVAQPGPGPGEPPPAQQ---EAESTPAAQ 160
           + PA  Q   A+  P   +PPPA++   E +S PA +
Sbjct: 653 EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPAEE 689



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 53/240 (22%), Positives = 95/240 (39%), Gaps = 24/240 (10%)

Query: 14  QPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQK 73
           +P P +     ++P  E+TP A+  +   + S   Q P + + PL   E PA+    S +
Sbjct: 282 EPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLV--EFPAEIQPPSAE 339

Query: 74  E-----------PRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKE 122
           E           P + ++S S+E       P  ++SP ++  LL +  + S Q     K 
Sbjct: 340 ESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVE--LLGEIRSPSAQ-----KA 392

Query: 123 SITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETP- 181
            I  Q   L      +  P   EPP  ++          +   + E      ST+ ETP 
Sbjct: 393 PIEVQ--PLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPA 450

Query: 182 -EQSDKQTTPVQGAKSKQGSLTELGFLTKLQELSIQRSALEWKALSEWVTDSESESDVGS 240
            E   +  +P+    + + +  E+  L   +  + +  A     LSE  +  E+ ++V S
Sbjct: 451 EEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAEVQS 510



 Score = 34.7 bits (78), Expect = 0.50
 Identities = 45/192 (23%), Positives = 74/192 (38%), Gaps = 17/192 (8%)

Query: 3   PGSKSVSRSDWQPE---PHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLT 59
           P +K VS  +   E   P     T  E       +A  E+   +     Q P + + P  
Sbjct: 562 PSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAE 621

Query: 60  QQETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGL 119
            Q  PA+      + P A++  A  +   A + PA  Q P  +      Q   +++ P  
Sbjct: 622 VQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA- 680

Query: 120 GKESITQQEPALRQRHVAQPGPGPGEPPPAQQ---EAESTPA----AQAKP--GAKREPS 170
             +S+  +E  + +   A   P P +  PA++   +  S PA     +  P   A  E S
Sbjct: 681 EVQSLPAEETPIEETLAAVHSP-PADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVS 739

Query: 171 APTESTSQETPE 182
            P    S++TPE
Sbjct: 740 PP---PSEQTPE 748


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 65/223 (29%), Positives = 87/223 (39%), Gaps = 53/223 (23%)

Query: 14  QPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQ-RPLTQQETPAQHDAESQ 72
           QP+P   P  PL     K P A P  +    +  Q  PA  Q  P  QQ+   +   + Q
Sbjct: 417 QPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQ 476

Query: 73  KEPRAQQKSAS-------------QEEFLAPQKPAPQQSP---------------YIQRV 104
           + P AQQ+ A              Q    A Q+PA  Q P               Y Q+ 
Sbjct: 477 QPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQ 536

Query: 105 LLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPG 164
              QQ+   Q    L ++ +  Q+ AL+Q+    P    G+ P  Q      PAA  +P 
Sbjct: 537 QQQQQQQQQQLATALHQQQLMTQQAALQQK----PTMAAGQQPQPQ------PAAAPQPA 586

Query: 165 AKREPS--APTESTSQETPEQSDKQTTP---VQGAKSKQGSLT 202
             +EP+  AP         +Q   QTTP   VQG   K GSLT
Sbjct: 587 PAQEPAIQAPVR-------QQPKVQTTPPPAVQG--QKVGSLT 620



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 45/188 (23%), Positives = 72/188 (38%), Gaps = 12/188 (6%)

Query: 6   KSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPA 65
           ++V  +  QP   Q P+  +  G  +  + Q   +  Q    QQ+       L QQ+   
Sbjct: 501 QAVHPATQQPAIAQFPV--VSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMT 558

Query: 66  QHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESIT 125
           Q  A  QK   A  +    +   APQ PAP Q P IQ  +  Q +  +   P +  + + 
Sbjct: 559 QQAALQQKPTMAAGQQPQPQPAAAPQ-PAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVG 617

Query: 126 QQEP--------ALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSA-PTEST 176
              P        A  +R ++          PA +  +   AA A+    +  SA  T S 
Sbjct: 618 SLTPPSSPKTQRAGHRRILSDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSG 677

Query: 177 SQETPEQS 184
           S  T +Q+
Sbjct: 678 SPRTSQQN 685



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 64/298 (21%), Positives = 106/298 (35%), Gaps = 39/298 (13%)

Query: 25  LEPGPEKTPIAQPES--------KTLQGSNTQQKP--ASNQRPLTQQETPAQHDAESQKE 74
           LEP P+K P     S        K     N Q  P  A    P+   E  A+   ++Q +
Sbjct: 294 LEPDPDKRPDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEPVKASEAAAK---KTQPK 350

Query: 75  PRAQQKSASQEEFLAP-QKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQ 133
            R      + E  +AP Q+P   Q+     +L  Q            ++  T Q P    
Sbjct: 351 ARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTP-------RKRATVQPPPQAA 403

Query: 134 RHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQG 193
               QPG     P P  Q   S P  Q +    ++P AP   T Q+TP  +  Q  P Q 
Sbjct: 404 GSSNQPGLLASVPQPKPQAPPSQPLPQTQ---AKQPQAP--PTPQQTP-STQAQGLPAQA 457

Query: 194 AKSKQGSLTELGFLTKLQELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPATMGGM 253
             + Q    +     K Q+   Q    + +    +    ++++          PAT    
Sbjct: 458 QATPQ---HQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQT---QQFQAVHPATQQPA 511

Query: 254 VAQGVKLGFKGKSGYKVMSGYSGTSPHEKTSARNHRHYQDTASRLIHNMDLRTMTQSL 311
           +AQ   +  +G S  ++M  +     +++   +  +  Q   +  +H   L T   +L
Sbjct: 512 IAQ-FPVVSQGGSQQQLMQNF-----YQQQQQQQQQQQQQQLATALHQQQLMTQQAAL 563


>gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4
           [Homo sapiens]
          Length = 818

 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 51/185 (27%), Positives = 75/185 (40%), Gaps = 14/185 (7%)

Query: 15  PEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKE 74
           PE    P  P +   EK   A PE +  + S    K   +    T++E P Q   ++Q +
Sbjct: 202 PEDQDLPPCPEDIAKEKRTPA-PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQ 260

Query: 75  PRAQQKSASQEEFLAPQKPAPQQSPYIQ-RVLLTQQEAASQQGPGLGKESITQQEPALRQ 133
            R      +Q   L P+    Q  P  Q RVL  Q +  SQ  P +   + TQ +P L++
Sbjct: 261 ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI-PSTDTQVQPKLQK 319

Query: 134 RHVAQPGP------GPGEPPPAQQEAESTPAAQAKPGAKREPSA-----PTESTSQETPE 182
           +   Q  P           P  QQEAE     Q +   + +PS      P    S + PE
Sbjct: 320 QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPE 379

Query: 183 QSDKQ 187
           Q+ +Q
Sbjct: 380 QTHEQ 384



 Score = 31.2 bits (69), Expect = 5.5
 Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 1/95 (1%)

Query: 828 LNSFLELSGRKSQKMSEPIAEPMRRSVSEAALAQPQGPLGTDSLKNLTLRDLSLRGNS-E 886
           L  F   + R+S     P+  PM  S    +   PQ    T S      +D S +    E
Sbjct: 123 LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVE 182

Query: 887 TSSDTPEMSLSAETLSPSTPSDVNFLLPPEDAGEE 921
             SD PE S  A      TP D +    PED  +E
Sbjct: 183 DKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKE 217


>gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3
           [Homo sapiens]
          Length = 837

 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 51/185 (27%), Positives = 75/185 (40%), Gaps = 14/185 (7%)

Query: 15  PEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKE 74
           PE    P  P +   EK   A PE +  + S    K   +    T++E P Q   ++Q +
Sbjct: 221 PEDQDLPPCPEDIAKEKRTPA-PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQ 279

Query: 75  PRAQQKSASQEEFLAPQKPAPQQSPYIQ-RVLLTQQEAASQQGPGLGKESITQQEPALRQ 133
            R      +Q   L P+    Q  P  Q RVL  Q +  SQ  P +   + TQ +P L++
Sbjct: 280 ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI-PSTDTQVQPKLQK 338

Query: 134 RHVAQPGP------GPGEPPPAQQEAESTPAAQAKPGAKREPSA-----PTESTSQETPE 182
           +   Q  P           P  QQEAE     Q +   + +PS      P    S + PE
Sbjct: 339 QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPE 398

Query: 183 QSDKQ 187
           Q+ +Q
Sbjct: 399 QTHEQ 403


>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2
           [Homo sapiens]
          Length = 842

 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 51/185 (27%), Positives = 75/185 (40%), Gaps = 14/185 (7%)

Query: 15  PEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKE 74
           PE    P  P +   EK   A PE +  + S    K   +    T++E P Q   ++Q +
Sbjct: 226 PEDQDLPPCPEDIAKEKRTPA-PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQ 284

Query: 75  PRAQQKSASQEEFLAPQKPAPQQSPYIQ-RVLLTQQEAASQQGPGLGKESITQQEPALRQ 133
            R      +Q   L P+    Q  P  Q RVL  Q +  SQ  P +   + TQ +P L++
Sbjct: 285 ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI-PSTDTQVQPKLQK 343

Query: 134 RHVAQPGP------GPGEPPPAQQEAESTPAAQAKPGAKREPSA-----PTESTSQETPE 182
           +   Q  P           P  QQEAE     Q +   + +PS      P    S + PE
Sbjct: 344 QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVHTQAQPSVQPQEHPPAQVSVQPPE 403

Query: 183 QSDKQ 187
           Q+ +Q
Sbjct: 404 QTHEQ 408



 Score = 31.2 bits (69), Expect = 5.5
 Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 1/95 (1%)

Query: 828 LNSFLELSGRKSQKMSEPIAEPMRRSVSEAALAQPQGPLGTDSLKNLTLRDLSLRGNS-E 886
           L  F   + R+S     P+  PM  S    +   PQ    T S      +D S +    E
Sbjct: 147 LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVE 206

Query: 887 TSSDTPEMSLSAETLSPSTPSDVNFLLPPEDAGEE 921
             SD PE S  A      TP D +    PED  +E
Sbjct: 207 DKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKE 241


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 51/186 (27%), Positives = 75/186 (40%), Gaps = 15/186 (8%)

Query: 16  EPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEP 75
           +P  +P+ P +P  ++T   +P S+        Q P   + P  QQ  PA+   +    P
Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP-AQQPGPAKPPTQQVGTP 418

Query: 76  RAQQKSASQEEFLAPQK-PAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQR 134
           +     A Q    +P K P P ++P  Q      +  A Q GPG  K S  Q  P     
Sbjct: 419 KPL---AQQPGLQSPAKAPGPTKTPVQQPG--PGKIPAQQAGPG--KTSAQQTGPTKPPS 471

Query: 135 HVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQGA 194
            +    PGP +PPP Q      P  Q  PG+ + PS    ST     +    + +P Q  
Sbjct: 472 QL----PGPAKPPPQQPGPAKPPPQQ--PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525

Query: 195 KSKQGS 200
            +K  S
Sbjct: 526 STKPPS 531



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 60/237 (25%), Positives = 97/237 (40%), Gaps = 46/237 (19%)

Query: 3    PGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTL-QGSNTQQKPASNQRPLTQQ 61
            PG  S S+   Q +P Q+   P +   + +P  +P++K + +GS T   P    RP   Q
Sbjct: 834  PGPSSESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMPKGSPTPPGP----RPTAGQ 887

Query: 62   ETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGK 121
              P       Q+ P+ Q++S      L     AP+  P       T QE  + +  G G 
Sbjct: 888  TVPTP-----QQSPKPQEQSRRFSLNLGSITDAPKSQP------TTPQETVTGKLFGFGA 936

Query: 122  ESITQQEPALRQRHVAQPGP----GPG----------EPPPAQQEAESTPAAQAKPG--- 164
               +Q    +      QPGP    GPG          +PP +Q   +ST  A   P    
Sbjct: 937  SIFSQASNLIST--AGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSI 994

Query: 165  -AKREPSAPT----ESTSQETP----EQSDKQTTPVQGAKSKQGSLTELGFLTKLQE 212
              K+E  AP     E  +++ P     +++K+  P++ +KS      +    TKL++
Sbjct: 995  PVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEK 1051



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 52/188 (27%), Positives = 69/188 (36%), Gaps = 20/188 (10%)

Query: 22  ITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKS 81
           + P  P P K PI QP      G    Q+P   +      + PAQ       +P AQQ  
Sbjct: 294 VKPSLPSPSKPPIQQP----TPGKPPAQQPGHEKSQPGPAKPPAQ--PSGLTKPLAQQPG 347

Query: 82  ASQEEFLAP---QKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQ 138
             +     P   + PA    P       T  E  S + PG        Q P + +    Q
Sbjct: 348 TVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG---PKALAQPPGVGKTPAQQ 404

Query: 139 PGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETP-EQSDKQTTPVQGAKSK 197
           PGP     PP QQ     P AQ +PG +    AP  +   +TP +Q      P Q A   
Sbjct: 405 PGPA---KPPTQQVGTPKPLAQ-QPGLQSPAKAPGPT---KTPVQQPGPGKIPAQQAGPG 457

Query: 198 QGSLTELG 205
           + S  + G
Sbjct: 458 KTSAQQTG 465



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 44/161 (27%), Positives = 62/161 (38%), Gaps = 21/161 (13%)

Query: 27  PGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEE 86
           PGP KTP+ QP    +     Q  P       T    P        K P  Q        
Sbjct: 434 PGPTKTPVQQPGPGKIPAQ--QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP------- 484

Query: 87  FLAPQKPAPQQSPYIQRVLLTQQEAASQ---QGPGLGKESITQQEPALRQRHVAQPG--- 140
              P KP PQQ    +    +QQ  +++   Q PG  K S   Q+P   +    QPG   
Sbjct: 485 --GPAKPPPQQPGSAKPP--SQQPGSTKPPPQQPGPAKPS--PQQPGSTKPPSQQPGSAK 538

Query: 141 PGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETP 181
           P   +P PA+  A+ +    ++ G+ +    PT S S + P
Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP 579



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 17/165 (10%)

Query: 26  EPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQE 85
           E   +K  + Q E    +G           +P+ +Q+ P +   +    P++   S+ Q 
Sbjct: 187 EETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSI--SSQQP 244

Query: 86  EFLAPQKPA-------PQQSPYIQRVLLTQQEAASQ----QGPGLGKESITQQEPALRQR 134
           E +  Q P        P Q+P      L  Q  AS+    Q   +  ES+    P+  + 
Sbjct: 245 EKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP 304

Query: 135 HVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQE 179
            + QP PG  +PP  Q   E +    AKP A  +PS  T+  +Q+
Sbjct: 305 PIQQPTPG--KPPAQQPGHEKSQPGPAKPPA--QPSGLTKPLAQQ 345



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 35/104 (33%), Positives = 45/104 (43%), Gaps = 13/104 (12%)

Query: 3   PGSKSVSRSDWQPEPHQRP----ITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPL 58
           PG  S  ++     P Q P      P +PGP K P  QP S         Q+P S  +P 
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS----AKPPSQQPGST-KPP 510

Query: 59  TQQETPAQHDAE---SQKEPRAQQKSAS-QEEFLAPQKPAPQQS 98
            QQ  PA+   +   S K P  Q  SA    +  +P KP+ QQS
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 17/117 (14%)

Query: 88  LAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPP 147
           LAP   +PQ  P ++   +T   A S+  P    +  + ++ A  ++ +++  P P +PP
Sbjct: 650 LAPVPSSPQ--PKLKTAPVTTTSAVSKSSPQ--PQQTSPKKDAAPKQDLSK-APEPKKPP 704

Query: 148 PA--QQEAESTPAAQAK----------PGAKREPSAPTESTSQETPEQSDKQTTPVQ 192
           P   Q     +P+A+AK          P   +EPS P+E       +   KQ   V+
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 24/133 (18%)

Query: 68  DAESQKEPRAQQKSASQEEFLAPQ---KPAPQQSPYIQRVLLTQQEAASQQGPGLGK--- 121
           D+E+ +E   +++   Q+E   P+   KP  QQ P         +    QQGPG      
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP--------PKPIPKQQGPGRDPLQQ 232

Query: 122 ----ESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTS 177
               +SI+ Q+P   ++  +QP   PG   P Q   ++     AK   +R+ S P    +
Sbjct: 233 DGTPKSISSQQP---EKIKSQP---PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286

Query: 178 QETPEQSDKQTTP 190
                +S K + P
Sbjct: 287 DIVRGESVKPSLP 299



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 50/224 (22%), Positives = 82/224 (36%), Gaps = 45/224 (20%)

Query: 28  GPEKTPI-AQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEE 86
           G +  P+ + P+ K      T     S   P  QQ +P +  A  Q   +A +       
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE------- 699

Query: 87  FLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEP 146
              P+KP P      Q  L     A ++Q P    +S+++              P P + 
Sbjct: 700 ---PKKPPPLVK---QPTLHGSPSAKAKQPPEA--DSLSK--------------PAPPKE 737

Query: 147 PPAQQEAESTPAAQAKPGAKR--EPSAPTESTSQETPE----------QSDKQTTP---V 191
           P    E +  P A  KP   +  +P+    S+S  T +          Q++++TTP    
Sbjct: 738 PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797

Query: 192 QGAKSKQGSLTELGFLTKLQELSIQRSALEWKALSEWVTDSESE 235
             AK  Q        ++     +I R A + K +S     SES+
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK 841



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 30/138 (21%), Positives = 55/138 (39%), Gaps = 13/138 (9%)

Query: 108 QQEAASQQGPGLGKESI---TQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPG 164
           Q  A   +  GL K S+     + P++ ++            PP Q      P   A+PG
Sbjct: 55  QIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELD-----SSHPPKQSGRPPDPGRPAQPG 109

Query: 165 AKREPSAPTESTSQETPEQSD-----KQTTPVQGAKSKQGSLTELGFLTKLQELSIQRSA 219
             +  +  T  + Q+ P +S      K++      K +  S    GFL+++  LS   S 
Sbjct: 110 LSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSV 169

Query: 220 LEWKALSEWVTDSESESD 237
           +      + ++DSE+  +
Sbjct: 170 VNKFNPFDLISDSEASQE 187



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 11/85 (12%)

Query: 17  PHQRPIT----PLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQ 72
           P Q+P +    P +PGP K    QP S         Q+P S  +P  QQ +PA+  A+  
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGST----KPPSQQPGS-AKPSAQQPSPAKPSAQQS 554

Query: 73  KEPRAQQKSAS--QEEFLAPQKPAP 95
            +P +Q  S    Q   ++P    P
Sbjct: 555 TKPVSQTGSGKPLQPPTVSPSAKQP 579


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 51/186 (27%), Positives = 75/186 (40%), Gaps = 15/186 (8%)

Query: 16  EPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEP 75
           +P  +P+ P +P  ++T   +P S+        Q P   + P  QQ  PA+   +    P
Sbjct: 360 KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTP-AQQPGPAKPPTQQVGTP 418

Query: 76  RAQQKSASQEEFLAPQK-PAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQR 134
           +     A Q    +P K P P ++P  Q      +  A Q GPG  K S  Q  P     
Sbjct: 419 KPL---AQQPGLQSPAKAPGPTKTPVQQPG--PGKIPAQQAGPG--KTSAQQTGPTKPPS 471

Query: 135 HVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQGA 194
            +    PGP +PPP Q      P  Q  PG+ + PS    ST     +    + +P Q  
Sbjct: 472 QL----PGPAKPPPQQPGPAKPPPQQ--PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG 525

Query: 195 KSKQGS 200
            +K  S
Sbjct: 526 STKPPS 531



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 60/237 (25%), Positives = 97/237 (40%), Gaps = 46/237 (19%)

Query: 3    PGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTL-QGSNTQQKPASNQRPLTQQ 61
            PG  S S+   Q +P Q+   P +   + +P  +P++K + +GS T   P    RP   Q
Sbjct: 834  PGPSSESKGQKQVDPVQKKEEPKKAQTKMSP--KPDAKPMPKGSPTPPGP----RPTAGQ 887

Query: 62   ETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGK 121
              P       Q+ P+ Q++S      L     AP+  P       T QE  + +  G G 
Sbjct: 888  TVPTP-----QQSPKPQEQSRRFSLNLGSITDAPKSQP------TTPQETVTGKLFGFGA 936

Query: 122  ESITQQEPALRQRHVAQPGP----GPG----------EPPPAQQEAESTPAAQAKPG--- 164
               +Q    +      QPGP    GPG          +PP +Q   +ST  A   P    
Sbjct: 937  SIFSQASNLIST--AGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSI 994

Query: 165  -AKREPSAPT----ESTSQETP----EQSDKQTTPVQGAKSKQGSLTELGFLTKLQE 212
              K+E  AP     E  +++ P     +++K+  P++ +KS      +    TKL++
Sbjct: 995  PVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEK 1051



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 52/188 (27%), Positives = 69/188 (36%), Gaps = 20/188 (10%)

Query: 22  ITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKS 81
           + P  P P K PI QP      G    Q+P   +      + PAQ       +P AQQ  
Sbjct: 294 VKPSLPSPSKPPIQQP----TPGKPPAQQPGHEKSQPGPAKPPAQ--PSGLTKPLAQQPG 347

Query: 82  ASQEEFLAP---QKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQ 138
             +     P   + PA    P       T  E  S + PG        Q P + +    Q
Sbjct: 348 TVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG---PKALAQPPGVGKTPAQQ 404

Query: 139 PGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETP-EQSDKQTTPVQGAKSK 197
           PGP     PP QQ     P AQ +PG +    AP  +   +TP +Q      P Q A   
Sbjct: 405 PGPA---KPPTQQVGTPKPLAQ-QPGLQSPAKAPGPT---KTPVQQPGPGKIPAQQAGPG 457

Query: 198 QGSLTELG 205
           + S  + G
Sbjct: 458 KTSAQQTG 465



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 44/161 (27%), Positives = 62/161 (38%), Gaps = 21/161 (13%)

Query: 27  PGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEE 86
           PGP KTP+ QP    +     Q  P       T    P        K P  Q        
Sbjct: 434 PGPTKTPVQQPGPGKIPAQ--QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP------- 484

Query: 87  FLAPQKPAPQQSPYIQRVLLTQQEAASQ---QGPGLGKESITQQEPALRQRHVAQPG--- 140
              P KP PQQ    +    +QQ  +++   Q PG  K S   Q+P   +    QPG   
Sbjct: 485 --GPAKPPPQQPGSAKPP--SQQPGSTKPPPQQPGPAKPS--PQQPGSTKPPSQQPGSAK 538

Query: 141 PGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETP 181
           P   +P PA+  A+ +    ++ G+ +    PT S S + P
Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP 579



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 41/165 (24%), Positives = 67/165 (40%), Gaps = 17/165 (10%)

Query: 26  EPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQE 85
           E   +K  + Q E    +G           +P+ +Q+ P +   +    P++   S+ Q 
Sbjct: 187 EETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSI--SSQQP 244

Query: 86  EFLAPQKPA-------PQQSPYIQRVLLTQQEAASQ----QGPGLGKESITQQEPALRQR 134
           E +  Q P        P Q+P      L  Q  AS+    Q   +  ES+    P+  + 
Sbjct: 245 EKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKP 304

Query: 135 HVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQE 179
            + QP PG  +PP  Q   E +    AKP A  +PS  T+  +Q+
Sbjct: 305 PIQQPTPG--KPPAQQPGHEKSQPGPAKPPA--QPSGLTKPLAQQ 345



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 35/104 (33%), Positives = 45/104 (43%), Gaps = 13/104 (12%)

Query: 3   PGSKSVSRSDWQPEPHQRP----ITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPL 58
           PG  S  ++     P Q P      P +PGP K P  QP S         Q+P S  +P 
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGS----AKPPSQQPGST-KPP 510

Query: 59  TQQETPAQHDAE---SQKEPRAQQKSAS-QEEFLAPQKPAPQQS 98
            QQ  PA+   +   S K P  Q  SA    +  +P KP+ QQS
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 17/117 (14%)

Query: 88  LAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPP 147
           LAP   +PQ  P ++   +T   A S+  P    +  + ++ A  ++ +++  P P +PP
Sbjct: 650 LAPVPSSPQ--PKLKTAPVTTTSAVSKSSPQ--PQQTSPKKDAAPKQDLSK-APEPKKPP 704

Query: 148 PA--QQEAESTPAAQAK----------PGAKREPSAPTESTSQETPEQSDKQTTPVQ 192
           P   Q     +P+A+AK          P   +EPS P+E       +   KQ   V+
Sbjct: 705 PLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK 761



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 24/133 (18%)

Query: 68  DAESQKEPRAQQKSASQEEFLAPQ---KPAPQQSPYIQRVLLTQQEAASQQGPGLGK--- 121
           D+E+ +E   +++   Q+E   P+   KP  QQ P         +    QQGPG      
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP--------PKPIPKQQGPGRDPLQQ 232

Query: 122 ----ESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTS 177
               +SI+ Q+P   ++  +QP   PG   P Q   ++     AK   +R+ S P    +
Sbjct: 233 DGTPKSISSQQP---EKIKSQP---PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286

Query: 178 QETPEQSDKQTTP 190
                +S K + P
Sbjct: 287 DIVRGESVKPSLP 299



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 50/224 (22%), Positives = 82/224 (36%), Gaps = 45/224 (20%)

Query: 28  GPEKTPI-AQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEE 86
           G +  P+ + P+ K      T     S   P  QQ +P +  A  Q   +A +       
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE------- 699

Query: 87  FLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEP 146
              P+KP P      Q  L     A ++Q P    +S+++              P P + 
Sbjct: 700 ---PKKPPPLVK---QPTLHGSPSAKAKQPPEA--DSLSK--------------PAPPKE 737

Query: 147 PPAQQEAESTPAAQAKPGAKR--EPSAPTESTSQETPE----------QSDKQTTP---V 191
           P    E +  P A  KP   +  +P+    S+S  T +          Q++++TTP    
Sbjct: 738 PSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKT 797

Query: 192 QGAKSKQGSLTELGFLTKLQELSIQRSALEWKALSEWVTDSESE 235
             AK  Q        ++     +I R A + K +S     SES+
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK 841



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 30/138 (21%), Positives = 55/138 (39%), Gaps = 13/138 (9%)

Query: 108 QQEAASQQGPGLGKESI---TQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPG 164
           Q  A   +  GL K S+     + P++ ++            PP Q      P   A+PG
Sbjct: 55  QIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELD-----SSHPPKQSGRPPDPGRPAQPG 109

Query: 165 AKREPSAPTESTSQETPEQSD-----KQTTPVQGAKSKQGSLTELGFLTKLQELSIQRSA 219
             +  +  T  + Q+ P +S      K++      K +  S    GFL+++  LS   S 
Sbjct: 110 LSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSV 169

Query: 220 LEWKALSEWVTDSESESD 237
           +      + ++DSE+  +
Sbjct: 170 VNKFNPFDLISDSEASQE 187



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 11/85 (12%)

Query: 17  PHQRPIT----PLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQ 72
           P Q+P +    P +PGP K    QP S         Q+P S  +P  QQ +PA+  A+  
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGST----KPPSQQPGS-AKPSAQQPSPAKPSAQQS 554

Query: 73  KEPRAQQKSAS--QEEFLAPQKPAP 95
            +P +Q  S    Q   ++P    P
Sbjct: 555 TKPVSQTGSGKPLQPPTVSPSAKQP 579


>gi|157041239 arylacetamide deacetylase-like 3 isoform 1 [Homo
            sapiens]
          Length = 350

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 26/64 (40%), Positives = 39/64 (60%)

Query: 964  IVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLP 1023
            +V +   SPL+A D ++  LP   IV+C  D + D+S++  +RL +LG PVT   +ED  
Sbjct: 260  VVLDVMCSPLIAEDDIVSQLPETCIVSCEYDALRDNSLLYKKRLEDLGVPVTWHHMEDGF 319

Query: 1024 HGFL 1027
            HG L
Sbjct: 320  HGVL 323



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 24/88 (27%), Positives = 42/88 (47%)

Query: 647 IVHFHGGGFVAQTSRSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAI 706
           IV++HGGG V  + ++H        +E  + ++++ Y   P+  FP  + +C  A    +
Sbjct: 58  IVYYHGGGGVMGSLKTHHGICSRLCKESDSVVLAVGYRKLPKHKFPVPVRDCLVATIHFL 117

Query: 707 KHCALLGSTGERICLAGDSAGGNLCFTV 734
           K     G    R+ + GDS GG +   V
Sbjct: 118 KSLDAYGVDPARVVVCGDSFGGAIAAVV 145


>gi|157041237 arylacetamide deacetylase-like 3 isoform 2 [Homo
            sapiens]
          Length = 280

 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 26/64 (40%), Positives = 39/64 (60%)

Query: 964  IVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLP 1023
            +V +   SPL+A D ++  LP   IV+C  D + D+S++  +RL +LG PVT   +ED  
Sbjct: 190  VVLDVMCSPLIAEDDIVSQLPETCIVSCEYDALRDNSLLYKKRLEDLGVPVTWHHMEDGF 249

Query: 1024 HGFL 1027
            HG L
Sbjct: 250  HGVL 253



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 17/73 (23%), Positives = 31/73 (42%)

Query: 662 SHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCALLGSTGERICL 721
           +H        +E  + ++++ Y   P+  FP  + +C  A    +K     G    R+ +
Sbjct: 3   THHGICSRLCKESDSVVLAVGYRKLPKHKFPVPVRDCLVATIHFLKSLDAYGVDPARVVV 62

Query: 722 AGDSAGGNLCFTV 734
            GDS GG +   V
Sbjct: 63  CGDSFGGAIAAVV 75


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 53/206 (25%), Positives = 82/206 (39%), Gaps = 18/206 (8%)

Query: 1   MEPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQ 60
           M P S +V  +       Q     L+   ++    Q +   LQ    QQ+    Q    Q
Sbjct: 136 MAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ--QQQFQAQQ 193

Query: 61  QETPAQHDAESQKEPRAQQKSASQEEFLA----PQKPAPQQSPYIQRV--LLTQQEAASQ 114
                Q  A  Q++ + QQ+   Q+  +      Q+   QQ   +QR+  L  QQ+   Q
Sbjct: 194 SAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQ 253

Query: 115 QGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQ-------QEAESTPAAQAKPGAKR 167
           Q     ++   Q +P ++Q  + QP P P +  P Q       Q  +  P  Q  P A+ 
Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQN 313

Query: 168 EPS-APTESTSQETPEQSDKQTTPVQ 192
           +PS  P +S +Q  P  S  Q  P Q
Sbjct: 314 QPSQLPPQSQTQ--PLVSQAQALPGQ 337



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 14/167 (8%)

Query: 26  EPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQE 85
           +P P  + +A      +  +  Q +    Q  L QQ+   Q   + Q   + QQ+   Q+
Sbjct: 128 QPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQ 187

Query: 86  EFLAPQKPAPQQSPYIQRVLLTQQEAASQQGP--------GLGKESITQQEPALRQRHVA 137
           +F A Q    QQ    Q V+  QQ+   QQ             ++ I QQ+  L++  +A
Sbjct: 188 QFQAQQSAMQQQ---FQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR--IA 242

Query: 138 QPGPGPGEPPPAQQEAESTPAAQAKPGAKREP-SAPTESTSQETPEQ 183
           Q      +    QQ+ +   A QA+P  ++ P   P    SQ  P+Q
Sbjct: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 49/201 (24%), Positives = 75/201 (37%), Gaps = 19/201 (9%)

Query: 14  QPEPHQRPITPLEPGPEKTPIAQPES-KTLQGSNTQQKPASNQRPLTQQETPAQHDAESQ 72
           QP   Q P+   +P P +   A P+  + +  +   Q P   Q+P   Q  P+Q   +SQ
Sbjct: 267 QPPIQQPPMQQPQPPPSQ---ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQ 323

Query: 73  KEPRAQQKSASQEEFLAPQKP-----APQ--QSPYIQRVLLTQQ------EAASQQGPGL 119
            +P   Q  A   + L  Q P     AP   Q P +Q  +  QQ      +AA    PG+
Sbjct: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV 383

Query: 120 GKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQE 179
              +    +  +  R    P       P +       P AQ    +    S+P+     +
Sbjct: 384 QMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQ 443

Query: 180 TPEQ--SDKQTTPVQGAKSKQ 198
           TP+      Q +P  G  S Q
Sbjct: 444 TPQSMPPPPQPSPQPGQPSSQ 464


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 53/206 (25%), Positives = 82/206 (39%), Gaps = 18/206 (8%)

Query: 1   MEPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQ 60
           M P S +V  +       Q     L+   ++    Q +   LQ    QQ+    Q    Q
Sbjct: 136 MAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ--QQQFQAQQ 193

Query: 61  QETPAQHDAESQKEPRAQQKSASQEEFLA----PQKPAPQQSPYIQRV--LLTQQEAASQ 114
                Q  A  Q++ + QQ+   Q+  +      Q+   QQ   +QR+  L  QQ+   Q
Sbjct: 194 SAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQ 253

Query: 115 QGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQ-------QEAESTPAAQAKPGAKR 167
           Q     ++   Q +P ++Q  + QP P P +  P Q       Q  +  P  Q  P A+ 
Sbjct: 254 QQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQN 313

Query: 168 EPS-APTESTSQETPEQSDKQTTPVQ 192
           +PS  P +S +Q  P  S  Q  P Q
Sbjct: 314 QPSQLPPQSQTQ--PLVSQAQALPGQ 337



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 52/207 (25%), Positives = 78/207 (37%), Gaps = 23/207 (11%)

Query: 14  QPEPHQRPITPLEPGPEKTPIAQPES-KTLQGSNTQQKPASNQRPLTQQETPAQHDAESQ 72
           QP   Q P+   +P P +   A P+  + +  +   Q P   Q+P   Q  P+Q   +SQ
Sbjct: 267 QPPIQQPPMQQPQPPPSQ---ALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQ 323

Query: 73  KEPRAQQKSASQEEFLAPQKP-----APQ--QSPYIQRVLLTQQ------EAASQQGPGL 119
            +P   Q  A   + L  Q P     AP   Q P +Q  +  QQ      +AA    PG+
Sbjct: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV 383

Query: 120 -----GKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTE 174
                    ++   P  +Q    Q  P P +P P   +  S P +    G    PS+   
Sbjct: 384 QVSQSSLPMLSSPSPG-QQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLP 442

Query: 175 STSQETPEQSDKQTTPVQGAKSKQGSL 201
           S S +  +      TP   +    G L
Sbjct: 443 SPSPQPSQSPVTARTPQNFSVPSPGPL 469



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 42/167 (25%), Positives = 69/167 (41%), Gaps = 14/167 (8%)

Query: 26  EPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQE 85
           +P P  + +A      +  +  Q +    Q  L QQ+   Q   + Q   + QQ+   Q+
Sbjct: 128 QPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQ 187

Query: 86  EFLAPQKPAPQQSPYIQRVLLTQQEAASQQGP--------GLGKESITQQEPALRQRHVA 137
           +F A Q    QQ    Q V+  QQ+   QQ             ++ I QQ+  L++  +A
Sbjct: 188 QFQAQQSAMQQQ---FQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQR--IA 242

Query: 138 QPGPGPGEPPPAQQEAESTPAAQAKPGAKREP-SAPTESTSQETPEQ 183
           Q      +    QQ+ +   A QA+P  ++ P   P    SQ  P+Q
Sbjct: 243 QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQ 289


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 61/250 (24%), Positives = 102/250 (40%), Gaps = 39/250 (15%)

Query: 1   MEPGSKSVSRSD---WQPEPHQRPITPLEPGPE--KTPIAQPESKTLQGSNTQQ------ 49
           M PGS   +R+     QP+P  +P    +P P+    P  QP++ T    + QQ      
Sbjct: 391 MLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVN 450

Query: 50  ----KPASNQRPLTQQE---TPAQHDAESQKEPRAQQKSASQ-EEFLAPQKPAPQQSPYI 101
               KP +   P  + E   TP     +  + P A+  S ++ +  L P+  +  +   +
Sbjct: 451 EGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEV 510

Query: 102 QRVLLT-----QQEAASQQGPGLG-----KESITQQEPALRQRHVAQPGPGPGEPPP--- 148
            RVL       ++  + +Q P +      K+   Q    L  RH    GPGPG P P   
Sbjct: 511 ARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRH---GGPGPGGPEPELS 567

Query: 149 ---AQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQGAKSKQGSLTELG 205
                 EA + P A A P A   P AP++S+  E P+  + ++   +    ++     L 
Sbjct: 568 PITEGSEARAGPPAPAPP-APIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLN 626

Query: 206 FLTKLQELSI 215
            L  L + ++
Sbjct: 627 PLVLLLDAAL 636


>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
           sapiens]
          Length = 828

 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 61/250 (24%), Positives = 102/250 (40%), Gaps = 39/250 (15%)

Query: 1   MEPGSKSVSRSD---WQPEPHQRPITPLEPGPE--KTPIAQPESKTLQGSNTQQ------ 49
           M PGS   +R+     QP+P  +P    +P P+    P  QP++ T    + QQ      
Sbjct: 391 MLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVN 450

Query: 50  ----KPASNQRPLTQQE---TPAQHDAESQKEPRAQQKSASQ-EEFLAPQKPAPQQSPYI 101
               KP +   P  + E   TP     +  + P A+  S ++ +  L P+  +  +   +
Sbjct: 451 EGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEV 510

Query: 102 QRVLLT-----QQEAASQQGPGLG-----KESITQQEPALRQRHVAQPGPGPGEPPP--- 148
            RVL       ++  + +Q P +      K+   Q    L  RH    GPGPG P P   
Sbjct: 511 ARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRH---GGPGPGGPEPELS 567

Query: 149 ---AQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQGAKSKQGSLTELG 205
                 EA + P A A P A   P AP++S+  E P+  + ++   +    ++     L 
Sbjct: 568 PITEGSEARAGPPAPAPP-APIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLN 626

Query: 206 FLTKLQELSI 215
            L  L + ++
Sbjct: 627 PLVLLLDAAL 636


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 49/198 (24%), Positives = 66/198 (33%), Gaps = 16/198 (8%)

Query: 3   PGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQE 62
           P S     S   P P   P +PLE  P   P   P S  L+   +    AS   P  ++ 
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552

Query: 63  --TPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPY-----IQRVLLTQQEAASQQ 115
             +P   +  +   P A + S   EE  +P  P P++SP        R+    +E+    
Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEE--SPMSPPPEESPMSPPPEASRLFPPFEESPLSP 610

Query: 116 GPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAA---QAKPGAKREPSAP 172
            P    E      P    R    P   P  PPP +      P        P   R    P
Sbjct: 611 PP----EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP 666

Query: 173 TESTSQETPEQSDKQTTP 190
            ES     PE+S     P
Sbjct: 667 EESPLSPPPEESPTSPPP 684



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 45/200 (22%), Positives = 72/200 (36%), Gaps = 28/200 (14%)

Query: 15  PEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASN-------QRPLTQQE-TPAQ 66
           P P +   +PL P PE++P + P   +      ++ PAS         RPL +   +P  
Sbjct: 442 PPPEE---SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPP 498

Query: 67  HDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGP------GLG 120
            ++     P +   S  +E  L+P + +P  SP ++  L    EA+    P         
Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEESP-PSPALETPLSPPPEASPLSPPFEESPLSPP 557

Query: 121 KESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQ----------AKPGAKREPS 170
            E +    P    R    P   P  PPP +      P A             P  +  P 
Sbjct: 558 PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPL 617

Query: 171 APTESTSQETPEQSDKQTTP 190
           +P    S+ +P   D   +P
Sbjct: 618 SPPPEASRLSPPPEDSPMSP 637



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 47/203 (23%), Positives = 79/203 (38%), Gaps = 20/203 (9%)

Query: 6    KSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPA 65
            +S+     QP+   +P+  L+   ++  + Q +    Q    QQ+    Q+ L QQ+   
Sbjct: 3878 QSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQ----QQQQLQQQQQLQQQQLQQ 3933

Query: 66   QHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESIT 125
            Q   +  ++ + QQ    Q++    Q+   QQ           Q+   QQ  GL  +S T
Sbjct: 3934 QQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQF----------QQQQQQQQMGLLNQSRT 3983

Query: 126  QQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKP---GAKREPSAPTESTSQETPE 182
               P  +Q+   Q   GPG P    Q   S+P A         K + +     +S+ T  
Sbjct: 3984 LLSPQQQQQQ--QVALGPGMPAKPLQHF-SSPGALGPTLLLTGKEQNTVDPAVSSEATEG 4040

Query: 183  QSDKQTTPVQGAKSKQGSLTELG 205
             S  Q  P+    + +   TE G
Sbjct: 4041 PSTHQGGPLAIGTTPESMATEPG 4063



 Score = 37.4 bits (85), Expect = 0.077
 Identities = 36/160 (22%), Positives = 60/160 (37%), Gaps = 26/160 (16%)

Query: 15  PEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKE 74
           P+P +  ++P    P  +P+ +    + Q   +   P S +  L+ +   +    E +K 
Sbjct: 799 PQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP 858

Query: 75  PRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQR 134
           P + +     EE    Q PAP++ P                 PG    S    EPAL + 
Sbjct: 859 PLSPRPEKPPEE--PGQCPAPEELPLF-------------PPPGEPSLSPLLGEPALSE- 902

Query: 135 HVAQPGPGPGEPP--PAQQEAESTPAAQAKPGAKREPSAP 172
                   PGEPP  P  +E   +P+ +     +  P  P
Sbjct: 903 --------PGEPPLSPLPEELPLSPSGEPSLSPQLMPPDP 934



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 39/194 (20%), Positives = 69/194 (35%), Gaps = 11/194 (5%)

Query: 15  PEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKE 74
           P P +   +PL P PE++P + P   +      +  P S     +    P +    S   
Sbjct: 664 PPPEE---SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPL 720

Query: 75  PRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQ--EPAL- 131
             +      +E  L P+   P  SP  +   L+ +       P   +  ++ Q  EP L 
Sbjct: 721 EESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLC 780

Query: 132 ---RQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQT 188
               + H++    GP    P  +E   +P  + +P     P  P  S   E    S +  
Sbjct: 781 AVPEEPHLSPQAEGP-HLSPQPEELHLSPQTE-EPHLSPVPEEPCLSPQPEESHLSPQSE 838

Query: 189 TPVQGAKSKQGSLT 202
            P    + ++  L+
Sbjct: 839 EPCLSPRPEESHLS 852



 Score = 32.3 bits (72), Expect = 2.5
 Identities = 44/190 (23%), Positives = 65/190 (34%), Gaps = 28/190 (14%)

Query: 2   EPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQ 61
           EP +  V+        H   + P EPGP      Q E+K L  +  Q +P        Q 
Sbjct: 384 EPDALYVACQGQPKGGHVTSMQPKEPGP-----LQCEAKPLGKAGVQLEP--------QL 430

Query: 62  ETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGK 121
           E P   +      P     S   EE  +P  P P+ S    R+    +E  +   P    
Sbjct: 431 EAPLNEEMPLLPPPEESPLSPPPEE--SPTSPPPEAS----RLSPPPEELPASPLP---- 480

Query: 122 ESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETP 181
           E++    P         P   P  PP      ES+P +  +      P     S + ETP
Sbjct: 481 EALHLSRPLEESPLSPPPEESPLSPP-----PESSPFSPLEESPLSPPEESPPSPALETP 535

Query: 182 EQSDKQTTPV 191
                + +P+
Sbjct: 536 LSPPPEASPL 545



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 44/176 (25%), Positives = 67/176 (38%), Gaps = 31/176 (17%)

Query: 17   PHQRPITP---LEPG-PEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQ 72
            P  +P TP   L+P  P    +A PES  + G    +   S          P   ++   
Sbjct: 2234 PRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLS---------PPPFGESRKA 2284

Query: 73   KEPRAQQKSASQEEFLAPQK---PAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEP 129
             E + ++  AS   +  P      +P    ++  + L        + P + K  +T   P
Sbjct: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLEL--------KTPDVFKAPLT---P 2333

Query: 130  ALRQRHVAQPGPG--PGEPPPAQQEAESTPAAQ--AKPGAKREPSAPTESTSQETP 181
               Q     PG G  P EPPPAQ  A S P+     +PG+  +P A    T +  P
Sbjct: 2334 RASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQP 2389



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 35/154 (22%), Positives = 53/154 (34%), Gaps = 7/154 (4%)

Query: 31   KTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEEFLAP 90
            K   A+  +    G    +  A   + +T+Q++  Q   +   + R QQK  +    +A 
Sbjct: 3540 KALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLD---QVRKQQKEHTN--LMAE 3594

Query: 91   QKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQ 150
             +   QQ    Q+    Q  A     P      +T+    L   H  QP  GP  P    
Sbjct: 3595 YRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGP--PGGQA 3652

Query: 151  QEAESTPAAQAKPGAKREPSAPTESTSQETPEQS 184
                 TP   A PG    P   T    Q+  + S
Sbjct: 3653 GGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHS 3686



 Score = 31.2 bits (69), Expect = 5.5
 Identities = 38/165 (23%), Positives = 57/165 (34%), Gaps = 10/165 (6%)

Query: 17   PHQRPITPLEPG----PEKTPIAQPESKTLQGSNTQQKPASN-----QRPLTQQETPAQH 67
            P    + P  PG    P++ P AQ  + +        +P S      Q PLT +  P   
Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPP 2392

Query: 68   DAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQ 127
            ++     PR+           +PQ  +  QSP   R L  +    S   P         +
Sbjct: 2393 ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR 2452

Query: 128  EPALRQ-RHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSA 171
             P+  Q R    P   P  P P +   ++   A    GA   P+A
Sbjct: 2453 PPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA 2497



 Score = 30.4 bits (67), Expect = 9.4
 Identities = 43/181 (23%), Positives = 60/181 (33%), Gaps = 18/181 (9%)

Query: 27   PGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEE 86
            PG    P        LQG   +     +  P  QQ+  A          R  Q+S +  +
Sbjct: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQAL------LMQRQLQQSQAVRQ 4239

Query: 87   FLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLG--KESITQQEPALRQRHVAQPG---- 140
                Q+P  Q SP +Q +L  Q +     GP  G  +E      P    R  A PG    
Sbjct: 4240 TPPYQEPGTQTSP-LQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALST 4298

Query: 141  -----PGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQGAK 195
                 P    PPP+  +    P+    P ++    A    T   TP+       P  G  
Sbjct: 4299 GPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRV 4358

Query: 196  S 196
            S
Sbjct: 4359 S 4359


>gi|114155127 regulator of G-protein signalling 3 isoform 6 [Homo
            sapiens]
          Length = 1198

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 88/389 (22%), Positives = 147/389 (37%), Gaps = 45/389 (11%)

Query: 6    KSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPA 65
            K     D  P     P   L PG +  P    +S + Q     Q+P S++   T + +P 
Sbjct: 697  KGPGAEDSPPSKEPSPGQELPPGQDLPP--NKDSPSGQEPAPSQEPLSSKDSATSEGSPP 754

Query: 66   QHDAESQK------EPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGP-- 117
              DA   K      EP   Q  +  ++  A Q+P P Q P + + L   QE+ ++  P  
Sbjct: 755  GPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRDLPPC 814

Query: 118  -GLGKESITQQEPALRQRHVAQPG--PGPGEPPPAQQEAESTPAAQ------AKPGAKRE 168
              L    ++    AL +  ++        G+PP A + A   P  +       K GA++ 
Sbjct: 815  QDLPPSQVSLPAKALTEDTMSSGDLLAATGDPPAAPRPAFVIPEVRLDSTYSQKAGAEQG 874

Query: 169  PSAPTEST--------SQETPEQSDKQTTP---VQGAKSKQGSLTEL------GFLTKLQ 211
             S   E           +E  E  D+ T+     + +++K+ S+ E       G   ++Q
Sbjct: 875  CSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQ 934

Query: 212  ELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPATMGGMVAQGV---KLGFKGKSGY 268
                +R+  E   L E      +       SD +  A+  GM +      +LG  G S +
Sbjct: 935  NSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSMH 994

Query: 269  KVMSGYSGTSPHEKTSARNHRHYQDTASRLIHNMDL-RTMTQSLVTLAEDNIAFFSSQGP 327
             +   ++G   H K S  +     D ASR   + +L + M   L      N +      P
Sbjct: 995  HLSLFFTG---HRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNES--PGAPP 1049

Query: 328  GETAQRLSGVFAGVREQALGLEPALGRLL 356
               A ++   F    E+AL    +L +LL
Sbjct: 1050 AGKADKMMKSFKPTSEEALKWGESLEKLL 1078



 Score = 34.7 bits (78), Expect = 0.50
 Identities = 37/168 (22%), Positives = 67/168 (39%), Gaps = 24/168 (14%)

Query: 37  PESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQ 96
           P+SK  +    +++    +  L + + P   D+   KEP   Q+    ++ L P K +P 
Sbjct: 676 PDSKMFETEADEKR----EMALEEGKGPGAEDSPPSKEPSPGQELPPGQD-LPPNKDSPS 730

Query: 97  -QSPYIQRVLLTQQEAASQQGPGLGKES-------ITQQEPALRQRHVAQPGPGPGEPPP 148
            Q P   +  L+ +++A+ +G   G ++         Q+ P  +     Q  P   EP P
Sbjct: 731 GQEPAPSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLP 790

Query: 149 AQQE--AESTPAAQAKPGAKREP---------SAPTESTSQETPEQSD 185
            Q     +  PA Q  P     P         S P ++ +++T    D
Sbjct: 791 HQDPLLTKDLPAIQESPTRDLPPCQDLPPSQVSLPAKALTEDTMSSGD 838


>gi|10864075 regulator of G-protein signalling 3 isoform 2 [Homo
           sapiens]
          Length = 519

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 88/389 (22%), Positives = 147/389 (37%), Gaps = 45/389 (11%)

Query: 6   KSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPA 65
           K     D  P     P   L PG +  P    +S + Q     Q+P S++   T + +P 
Sbjct: 18  KGPGAEDSPPSKEPSPGQELPPGQDLPP--NKDSPSGQEPAPSQEPLSSKDSATSEGSPP 75

Query: 66  QHDAESQK------EPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGP-- 117
             DA   K      EP   Q  +  ++  A Q+P P Q P + + L   QE+ ++  P  
Sbjct: 76  GPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRDLPPC 135

Query: 118 -GLGKESITQQEPALRQRHVAQPG--PGPGEPPPAQQEAESTPAAQ------AKPGAKRE 168
             L    ++    AL +  ++        G+PP A + A   P  +       K GA++ 
Sbjct: 136 QDLPPSQVSLPAKALTEDTMSSGDLLAATGDPPAAPRPAFVIPEVRLDSTYSQKAGAEQG 195

Query: 169 PSAPTEST--------SQETPEQSDKQTTP---VQGAKSKQGSLTEL------GFLTKLQ 211
            S   E           +E  E  D+ T+     + +++K+ S+ E       G   ++Q
Sbjct: 196 CSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQ 255

Query: 212 ELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPATMGGMVAQGV---KLGFKGKSGY 268
               +R+  E   L E      +       SD +  A+  GM +      +LG  G S +
Sbjct: 256 NSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSMH 315

Query: 269 KVMSGYSGTSPHEKTSARNHRHYQDTASRLIHNMDL-RTMTQSLVTLAEDNIAFFSSQGP 327
            +   ++G   H K S  +     D ASR   + +L + M   L      N +      P
Sbjct: 316 HLSLFFTG---HRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNES--PGAPP 370

Query: 328 GETAQRLSGVFAGVREQALGLEPALGRLL 356
              A ++   F    E+AL    +L +LL
Sbjct: 371 AGKADKMMKSFKPTSEEALKWGESLEKLL 399



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 34/147 (23%), Positives = 58/147 (39%), Gaps = 20/147 (13%)

Query: 58  LTQQETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQ-QSPYIQRVLLTQQEAASQQG 116
           L + + P   D+   KEP   Q+    ++ L P K +P  Q P   +  L+ +++A+ +G
Sbjct: 14  LEEGKGPGAEDSPPSKEPSPGQELPPGQD-LPPNKDSPSGQEPAPSQEPLSSKDSATSEG 72

Query: 117 PGLGKES-------ITQQEPALRQRHVAQPGPGPGEPPPAQQE--AESTPAAQAKPGAKR 167
              G ++         Q+ P  +     Q  P   EP P Q     +  PA Q  P    
Sbjct: 73  SPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRDL 132

Query: 168 EP---------SAPTESTSQETPEQSD 185
            P         S P ++ +++T    D
Sbjct: 133 PPCQDLPPSQVSLPAKALTEDTMSSGD 159


>gi|62865651 regulator of G-protein signalling 3 isoform 1 [Homo
           sapiens]
          Length = 917

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 88/389 (22%), Positives = 147/389 (37%), Gaps = 45/389 (11%)

Query: 6   KSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPA 65
           K     D  P     P   L PG +  P    +S + Q     Q+P S++   T + +P 
Sbjct: 416 KGPGAEDSPPSKEPSPGQELPPGQDLPP--NKDSPSGQEPAPSQEPLSSKDSATSEGSPP 473

Query: 66  QHDAESQK------EPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGP-- 117
             DA   K      EP   Q  +  ++  A Q+P P Q P + + L   QE+ ++  P  
Sbjct: 474 GPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLPHQDPLLTKDLPAIQESPTRDLPPC 533

Query: 118 -GLGKESITQQEPALRQRHVAQPG--PGPGEPPPAQQEAESTPAAQ------AKPGAKRE 168
             L    ++    AL +  ++        G+PP A + A   P  +       K GA++ 
Sbjct: 534 QDLPPSQVSLPAKALTEDTMSSGDLLAATGDPPAAPRPAFVIPEVRLDSTYSQKAGAEQG 593

Query: 169 PSAPTEST--------SQETPEQSDKQTTP---VQGAKSKQGSLTEL------GFLTKLQ 211
            S   E           +E  E  D+ T+     + +++K+ S+ E       G   ++Q
Sbjct: 594 CSGDEEDAEEAEEVEEGEEGEEDEDEDTSDDNYGERSEAKRSSMIETGQGAEGGLSLRVQ 653

Query: 212 ELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPATMGGMVAQGV---KLGFKGKSGY 268
               +R+  E   L E      +       SD +  A+  GM +      +LG  G S +
Sbjct: 654 NSLRRRTHSEGSLLQEPRGPCFASDTTLHCSDGEGAASTWGMPSPSTLKKELGRNGGSMH 713

Query: 269 KVMSGYSGTSPHEKTSARNHRHYQDTASRLIHNMDL-RTMTQSLVTLAEDNIAFFSSQGP 327
            +   ++G   H K S  +     D ASR   + +L + M   L      N +      P
Sbjct: 714 HLSLFFTG---HRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNES--PGAPP 768

Query: 328 GETAQRLSGVFAGVREQALGLEPALGRLL 356
              A ++   F    E+AL    +L +LL
Sbjct: 769 AGKADKMMKSFKPTSEEALKWGESLEKLL 797



 Score = 34.7 bits (78), Expect = 0.50
 Identities = 37/168 (22%), Positives = 67/168 (39%), Gaps = 24/168 (14%)

Query: 37  PESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQ 96
           P+SK  +    +++    +  L + + P   D+   KEP   Q+    ++ L P K +P 
Sbjct: 395 PDSKMFETEADEKR----EMALEEGKGPGAEDSPPSKEPSPGQELPPGQD-LPPNKDSPS 449

Query: 97  -QSPYIQRVLLTQQEAASQQGPGLGKES-------ITQQEPALRQRHVAQPGPGPGEPPP 148
            Q P   +  L+ +++A+ +G   G ++         Q+ P  +     Q  P   EP P
Sbjct: 450 GQEPAPSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQEPPPAQDLSPCQDLPAGQEPLP 509

Query: 149 AQQE--AESTPAAQAKPGAKREP---------SAPTESTSQETPEQSD 185
            Q     +  PA Q  P     P         S P ++ +++T    D
Sbjct: 510 HQDPLLTKDLPAIQESPTRDLPPCQDLPPSQVSLPAKALTEDTMSSGD 557


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 72/306 (23%), Positives = 107/306 (34%), Gaps = 30/306 (9%)

Query: 34  IAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEEFLAPQKP 93
           + Q + K  +  N ++K    + P    E  A       +E  A   S ++EE +   + 
Sbjct: 666 LQQHKLKMEKERNARRK--KKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEA 723

Query: 94  APQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQQEA 153
               S   + +     EAA   G    K   T             P PGP  PPP    A
Sbjct: 724 TVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADG--------PPPGPPTPPPEDIPA 775

Query: 154 --ESTPAAQA-----KPGAKREPSAPTESTSQETPEQSDKQTTPVQGAKSKQGSLTELGF 206
             E TPA++A      P A   PSAP     +E  E+      PV+  + ++    E   
Sbjct: 776 PTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAE--- 832

Query: 207 LTKLQELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPATMGGMVAQGVKLGFKGKS 266
                EL++     E    SE   ++E     G  ++       G + A+      +G S
Sbjct: 833 -----ELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKK----EGGS 883

Query: 267 GYKVMSGYSGTSPHEKTSARNHRHYQDTASRLIHNMDLRTMTQSLVTLAEDNIAFFSSQG 326
           G    +  SG      +SA       D A     N  L +   SL+T   D  A  S Q 
Sbjct: 884 GRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNR-LLSPRPSLLTPTGDPRANASPQK 942

Query: 327 PGETAQ 332
           P +  Q
Sbjct: 943 PLDLKQ 948



 Score = 32.3 bits (72), Expect = 2.5
 Identities = 37/191 (19%), Positives = 69/191 (36%), Gaps = 43/191 (22%)

Query: 43  QGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQ 102
           +G + QQ+    Q+   QQ+ P    ++ +K+ + ++K A +EE    +KP         
Sbjct: 490 RGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEE----EKP--------- 536

Query: 103 RVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAK 162
                              E    +E  L+++     G    E      +   T  +Q +
Sbjct: 537 -------------------EVENDKEDLLKEKTDDTSGEDNDEKEAVASKGRKTANSQGR 577

Query: 163 PGAKREPSAPTESTSQETPEQSDKQTTPVQGAKSKQGSLTELGFLTKLQELSIQRSALE- 221
              +   S   E+ S+E         TP Q A+     L E    T+ +  + ++  LE 
Sbjct: 578 RKGRITRSMANEANSEEA-------ITPQQSAELASMELNESSRWTEEEMETAKKGLLEH 630

Query: 222 ---WKALSEWV 229
              W A++  V
Sbjct: 631 GRNWSAIARMV 641



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 36/169 (21%), Positives = 64/169 (37%), Gaps = 15/169 (8%)

Query: 26   EPGPEKTPIAQPESKTLQGS-NTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQ----K 80
            E GP K   A+    T +G+   ++K   + R  T + + A  D++S     A +    +
Sbjct: 854  EEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAE 913

Query: 81   SASQEEFLAPQKPA------PQQSPYIQRVLLTQQEAASQQGPGLGKESITQ-QEPALRQ 133
               +   L+P+         P+ +   Q+ L  +Q    Q+   +    +T+  EP    
Sbjct: 914  GGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQ--LKQRAAAIPPIQVTKVHEPPRED 971

Query: 134  RHVAQPGP-GPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETP 181
                +P P  P  P   Q E+++     + P  K    AP      E P
Sbjct: 972  AAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKP 1020



 Score = 30.4 bits (67), Expect = 9.4
 Identities = 64/271 (23%), Positives = 87/271 (32%), Gaps = 43/271 (15%)

Query: 15   PEPHQRPITPLEPGPEKTPIAQPESKTLQ--GSNTQQKPASNQRPLTQQ-ETPA---QHD 68
            P     P  P  P P      QPES   Q  GS+ + K  S   P  ++ E P       
Sbjct: 968  PREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFA 1027

Query: 69   AESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPG----LGKESI 124
            AE+QK P       S   F  P +   + SP+          A S   PG    LG    
Sbjct: 1028 AEAQKLPGDPPCWTSGLPFPVPPREVIKASPH-----APDPSAFSYAPPGHPLPLGLHDT 1082

Query: 125  TQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGA-------------KREPSA 171
                     R V    P    PPP    A+     + + GA                  A
Sbjct: 1083 A--------RPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAKA 1134

Query: 172  PTESTSQETPEQSD-KQTTPVQGAKSKQGSLTELGFLTKLQELSI----QRSALEWKALS 226
            P    +   P   D K+  P  G K +Q  L+  G     + L +    + S L   AL 
Sbjct: 1135 PVGPVTMGLPLPMDPKKLAPFSGVKQEQ--LSPRGQAGPPESLGVPTAQEASVLRGTALG 1192

Query: 227  EWVTDSESESDVGSSSDTDSPATMGGMVAQG 257
                 S ++    +   +DS  T  G +  G
Sbjct: 1193 SVPGGSITKGIPSTRVPSDSAITYRGSITHG 1223


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 45/191 (23%), Positives = 68/191 (35%), Gaps = 19/191 (9%)

Query: 15  PEPHQ-----RPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDA 69
           P PH      +   P  P P   P   P  ++  G++      S + P      P QH  
Sbjct: 624 PSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTG 683

Query: 70  ESQKEPRA-------QQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKE 122
           +   +P A       ++ S+S     AP  P PQ  P  Q   L   +  SQ  P     
Sbjct: 684 QPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQ--PPTQATPLMHTKPNSQGPP--NPM 739

Query: 123 SITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKRE---PSAPTESTSQE 179
           ++  +    +  H     P P   PP  ++  S PA Q   G   E   P A T    + 
Sbjct: 740 ALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRP 799

Query: 180 TPEQSDKQTTP 190
            P+  ++ + P
Sbjct: 800 VPKPRNRPSVP 810



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 42/186 (22%), Positives = 63/186 (33%), Gaps = 32/186 (17%)

Query: 6   KSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPA 65
           K +S +   P P     T +  GPE  P    +S   + S+      S+   L Q  +P 
Sbjct: 517 KHISPAFQPPLPPTDGSTVVPAGPEPPP----QSSRAESSSGGGTVPSSAGILEQGPSPG 572

Query: 66  QHDAESQKEP--RAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKES 123
                  K+P   A          +A  +  PQ +    ++ + Q   A+   P   + +
Sbjct: 573 DGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRA 632

Query: 124 ITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQ 183
           + +  PA          P PG PPP        P  Q+  G           TSQ  P  
Sbjct: 633 VKKPAPA---------PPKPGNPPPGH------PGGQSSSG-----------TSQHPPSL 666

Query: 184 SDKQTT 189
           S K  T
Sbjct: 667 SPKPPT 672


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 45/191 (23%), Positives = 68/191 (35%), Gaps = 19/191 (9%)

Query: 15  PEPHQ-----RPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDA 69
           P PH      +   P  P P   P   P  ++  G++      S + P      P QH  
Sbjct: 546 PSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTG 605

Query: 70  ESQKEPRA-------QQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKE 122
           +   +P A       ++ S+S     AP  P PQ  P  Q   L   +  SQ  P     
Sbjct: 606 QPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQ--PPTQATPLMHTKPNSQGPP--NPM 661

Query: 123 SITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKRE---PSAPTESTSQE 179
           ++  +    +  H     P P   PP  ++  S PA Q   G   E   P A T    + 
Sbjct: 662 ALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRP 721

Query: 180 TPEQSDKQTTP 190
            P+  ++ + P
Sbjct: 722 VPKPRNRPSVP 732


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 46/166 (27%), Positives = 61/166 (36%), Gaps = 15/166 (9%)

Query: 17  PHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPR 76
           P   P+TPLEP  +   +  PE +T   S    KPAS   P   +  P     ESQK   
Sbjct: 146 PKPTPLTPLEP-QKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPV---CESQKLAP 201

Query: 77  AQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPG-LGKESITQQEPALRQRH 135
                        PQKPAP     ++  L   +       P  LG  S +  E  +    
Sbjct: 202 VPSPE--------PQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAAS 253

Query: 136 VAQPGPGPGEPPPAQQEAESTPAAQAKPGAKR--EPSAPTESTSQE 179
               GP P   P +++ A +T     KP      EP  P  + S E
Sbjct: 254 PEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPE 299



 Score = 37.0 bits (84), Expect = 0.10
 Identities = 45/193 (23%), Positives = 70/193 (36%), Gaps = 28/193 (14%)

Query: 6   KSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPA 65
           +SV  +   P+P ++   P   GP     + PES  L  S     P+    P +++    
Sbjct: 216 ESVKATLSNPKPQKQSHFPETLGPPSA--SSPESPVLAASPEPWGPSPAASPESRKSART 273

Query: 66  QHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGP-------- 117
                +  EPR    S S E    P KP P  SP  +R        + + GP        
Sbjct: 274 -----TSPEPRKPSPSESPE----PWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWK 324

Query: 118 -----GLGKESITQQEPALRQ---RHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREP 169
                  G     +  P++     + +    PGP +P P+   A S  ++   P + + P
Sbjct: 325 SNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSA-SWKSSSVSPSSWKSP 383

Query: 170 SAPTESTSQETPE 182
            A  ES     PE
Sbjct: 384 PASPESWKSGPPE 396



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 44/182 (24%), Positives = 68/182 (37%), Gaps = 21/182 (11%)

Query: 5   SKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETP 64
           SK  S   W  +P  +     E  P K+P   PE + +  ++ + K      P    ET 
Sbjct: 83  SKHASPDKWNDKPKNQ--LNKETDPVKSP-PLPEHQKIPCNSAEPKSI----PALSMETQ 135

Query: 65  AQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEA--ASQQGPGLGKE 122
                 S + P+    +      L PQKP    SP +Q  L + + +  AS   P   K 
Sbjct: 136 KLGSVLSPESPKPTPLTP-----LEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKS 190

Query: 123 SITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKR---EPSAPTESTSQE 179
               +     Q+    P P P +P P   E+     +  KP  +    E   P  ++S E
Sbjct: 191 VPVCES----QKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPE 246

Query: 180 TP 181
           +P
Sbjct: 247 SP 248


>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1
           [Homo sapiens]
          Length = 898

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 51/185 (27%), Positives = 76/185 (41%), Gaps = 13/185 (7%)

Query: 15  PEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKE 74
           PE    P  P +   EK   A PE +  + S    K   +    T++E P Q   ++Q +
Sbjct: 226 PEDQDLPPCPEDIAKEKRTPA-PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQ 284

Query: 75  PRAQQKSASQEEFLAPQKPAPQQSPYIQ-RVLLTQQEAASQQGPGLGKESITQQEPALRQ 133
            R      +Q   L P+    Q  P  Q RVL  Q +  SQ  P +   + TQ +P L++
Sbjct: 285 ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI-PSTDTQVQPKLQK 343

Query: 134 RHVAQPGP------GPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQ 187
           +   Q  P           P  QQEAE  P  Q +P  + +P A ++   Q   +Q  + 
Sbjct: 344 QAQTQTSPEHLVLQQKQVQPQLQQEAE--PQKQVQP--QVQPQAHSQGPRQVQLQQEAEP 399

Query: 188 TTPVQ 192
              VQ
Sbjct: 400 LKQVQ 404



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 40/150 (26%), Positives = 58/150 (38%), Gaps = 14/150 (9%)

Query: 23  TPLEPGPEKTPIAQ--PESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQK 80
           T ++P  +K    Q  PE   LQ    Q        P  QQE   Q   + Q +P+A  +
Sbjct: 335 TQVQPKLQKQAQTQTSPEHLVLQQKQVQ--------PQLQQEAEPQKQVQPQVQPQAHSQ 386

Query: 81  SASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPG 140
              Q +     +P  Q  P +Q    +Q     Q    L K+  TQ  P +  +  AQP 
Sbjct: 387 GPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQL--QLQKQVQTQTYPQVHTQ--AQPS 442

Query: 141 PGPGEPPPAQQEAESTPAAQAKPGAKREPS 170
             P E PPAQ   +       +P  + + S
Sbjct: 443 VQPQEHPPAQVSVQPPEQTHEQPHTQPQVS 472



 Score = 31.2 bits (69), Expect = 5.5
 Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 1/95 (1%)

Query: 828 LNSFLELSGRKSQKMSEPIAEPMRRSVSEAALAQPQGPLGTDSLKNLTLRDLSLRGNS-E 886
           L  F   + R+S     P+  PM  S    +   PQ    T S      +D S +    E
Sbjct: 147 LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVE 206

Query: 887 TSSDTPEMSLSAETLSPSTPSDVNFLLPPEDAGEE 921
             SD PE S  A      TP D +    PED  +E
Sbjct: 207 DKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKE 241


>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
           [Homo sapiens]
          Length = 898

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 51/185 (27%), Positives = 76/185 (41%), Gaps = 13/185 (7%)

Query: 15  PEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKE 74
           PE    P  P +   EK   A PE +  + S    K   +    T++E P Q   ++Q +
Sbjct: 226 PEDQDLPPCPEDIAKEKRTPA-PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQ 284

Query: 75  PRAQQKSASQEEFLAPQKPAPQQSPYIQ-RVLLTQQEAASQQGPGLGKESITQQEPALRQ 133
            R      +Q   L P+    Q  P  Q RVL  Q +  SQ  P +   + TQ +P L++
Sbjct: 285 ARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI-PSTDTQVQPKLQK 343

Query: 134 RHVAQPGP------GPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQ 187
           +   Q  P           P  QQEAE  P  Q +P  + +P A ++   Q   +Q  + 
Sbjct: 344 QAQTQTSPEHLVLQQKQVQPQLQQEAE--PQKQVQP--QVQPQAHSQGPRQVQLQQEAEP 399

Query: 188 TTPVQ 192
              VQ
Sbjct: 400 LKQVQ 404



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 40/150 (26%), Positives = 58/150 (38%), Gaps = 14/150 (9%)

Query: 23  TPLEPGPEKTPIAQ--PESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQK 80
           T ++P  +K    Q  PE   LQ    Q        P  QQE   Q   + Q +P+A  +
Sbjct: 335 TQVQPKLQKQAQTQTSPEHLVLQQKQVQ--------PQLQQEAEPQKQVQPQVQPQAHSQ 386

Query: 81  SASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPG 140
              Q +     +P  Q  P +Q    +Q     Q    L K+  TQ  P +  +  AQP 
Sbjct: 387 GPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQL--QLQKQVQTQTYPQVHTQ--AQPS 442

Query: 141 PGPGEPPPAQQEAESTPAAQAKPGAKREPS 170
             P E PPAQ   +       +P  + + S
Sbjct: 443 VQPQEHPPAQVSVQPPEQTHEQPHTQPQVS 472



 Score = 31.2 bits (69), Expect = 5.5
 Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 1/95 (1%)

Query: 828 LNSFLELSGRKSQKMSEPIAEPMRRSVSEAALAQPQGPLGTDSLKNLTLRDLSLRGNS-E 886
           L  F   + R+S     P+  PM  S    +   PQ    T S      +D S +    E
Sbjct: 147 LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVE 206

Query: 887 TSSDTPEMSLSAETLSPSTPSDVNFLLPPEDAGEE 921
             SD PE S  A      TP D +    PED  +E
Sbjct: 207 DKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKE 241


>gi|226423952 arylacetamide deacetylase-like 1 isoform c [Homo
            sapiens]
          Length = 275

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 1/87 (1%)

Query: 939  AAFPEGFHPRRSSQGATQMPLYSSPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLD 998
            A+F + + P   + G  ++ +   P + +   +PL+A  ++L+ LP  +I+ C  D + D
Sbjct: 161  ASFTKNYKPVVQTTGNARI-VQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRD 219

Query: 999  DSVMLARRLRNLGQPVTLRVVEDLPHG 1025
            D +M A+RL + G  VTL   ED  HG
Sbjct: 220  DGIMYAKRLESAGVEVTLDHFEDGFHG 246



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 18/123 (14%)

Query: 671 AQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCALLGSTGE--RICLAGDSAGG 728
           A+EL A I+SI+Y L P+  FP  + +   A  + +K   L     +  RIC++GDSAGG
Sbjct: 2   AEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGG 61

Query: 729 NLCFTVALRAAAYGVRVPDGI---------MAAYPATMLQPAASPSRLLSLMDPLLPLSV 779
           NL       AAA G +                 YP        +PS   ++  P+LP  V
Sbjct: 62  NL-------AAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYV 114

Query: 780 LSK 782
           + K
Sbjct: 115 MVK 117


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,532,896
Number of Sequences: 37866
Number of extensions: 2352640
Number of successful extensions: 21951
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 960
Number of HSP's that attempted gapping in prelim test: 15764
Number of HSP's gapped (non-prelim): 5286
length of query: 1076
length of database: 18,247,518
effective HSP length: 113
effective length of query: 963
effective length of database: 13,968,660
effective search space: 13451819580
effective search space used: 13451819580
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.