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Search of human proteins with 21245124
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21245124 adenosine deaminase domain containing 1
(testis-specific) isoform 1 [Homo sapiens]
(576 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21245124 adenosine deaminase domain containing 1 (testis-spec... 1147 0.0
gi|226529650 adenosine deaminase domain containing 1 (testis-spe... 1115 0.0
gi|226530771 adenosine deaminase domain containing 1 (testis-spe... 1109 0.0
gi|223972690 adenosine deaminase domain containing 2 isoform 2 [... 189 8e-48
gi|223972688 adenosine deaminase domain containing 2 isoform 1 [... 187 3e-47
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 160 4e-39
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 158 1e-38
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 147 3e-35
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 147 3e-35
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 138 2e-32
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 136 5e-32
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 136 5e-32
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 134 2e-31
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 132 1e-30
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens] 55 1e-07
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 42 0.002
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 42 0.002
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 42 0.002
gi|7657625 staufen homolog 2 [Homo sapiens] 40 0.004
gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens] 36 0.11
gi|82659089 staufen isoform a [Homo sapiens] 35 0.14
gi|82659087 staufen isoform b [Homo sapiens] 35 0.14
gi|82659085 staufen isoform a [Homo sapiens] 35 0.14
gi|82659083 staufen isoform a [Homo sapiens] 35 0.14
gi|82659091 staufen isoform c [Homo sapiens] 33 0.71
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 32 1.6
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 32 1.6
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 32 1.6
gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens] 32 1.6
gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens] 32 2.1
>gi|21245124 adenosine deaminase domain containing 1
(testis-specific) isoform 1 [Homo sapiens]
Length = 576
Score = 1147 bits (2966), Expect = 0.0
Identities = 576/576 (100%), Positives = 576/576 (100%)
Query: 1 MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF 60
MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF
Sbjct: 1 MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF 60
Query: 61 PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT 120
PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT
Sbjct: 61 PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT 120
Query: 121 GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP 180
GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP
Sbjct: 121 GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP 180
Query: 181 FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE 240
FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE
Sbjct: 181 FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE 240
Query: 241 RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMM 300
RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMM
Sbjct: 241 RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMM 300
Query: 301 EKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHV 360
EKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHV
Sbjct: 301 EKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHV 360
Query: 361 AVEGKIYLTVYCPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGN 420
AVEGKIYLTVYCPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGN
Sbjct: 361 AVEGKIYLTVYCPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGN 420
Query: 421 CSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD 480
CSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD
Sbjct: 421 CSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD 480
Query: 481 VSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKC 540
VSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKC
Sbjct: 481 VSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKC 540
Query: 541 MSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM 576
MSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM
Sbjct: 541 MSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM 576
>gi|226529650 adenosine deaminase domain containing 1
(testis-specific) isoform 2 [Homo sapiens]
Length = 565
Score = 1115 bits (2884), Expect = 0.0
Identities = 565/576 (98%), Positives = 565/576 (98%), Gaps = 11/576 (1%)
Query: 1 MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF 60
MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF
Sbjct: 1 MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF 60
Query: 61 PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT 120
PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT
Sbjct: 61 PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT 120
Query: 121 GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP 180
GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP
Sbjct: 121 GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP 180
Query: 181 FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE 240
FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE
Sbjct: 181 FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE 240
Query: 241 RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMM 300
RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLL SKNPAMM
Sbjct: 241 RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLL-----------SKNPAMM 289
Query: 301 EKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHV 360
EKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHV
Sbjct: 290 EKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHV 349
Query: 361 AVEGKIYLTVYCPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGN 420
AVEGKIYLTVYCPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGN
Sbjct: 350 AVEGKIYLTVYCPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGN 409
Query: 421 CSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD 480
CSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD
Sbjct: 410 CSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD 469
Query: 481 VSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKC 540
VSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKC
Sbjct: 470 VSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKC 529
Query: 541 MSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM 576
MSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM
Sbjct: 530 MSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM 565
>gi|226530771 adenosine deaminase domain containing 1
(testis-specific) isoform 3 [Homo sapiens]
Length = 558
Score = 1109 bits (2868), Expect = 0.0
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 19 MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP 78
MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP
Sbjct: 1 MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP 60
Query: 79 PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ 138
PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ
Sbjct: 61 PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ 120
Query: 139 YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH 198
YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH
Sbjct: 121 YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH 180
Query: 199 YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS 258
YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS
Sbjct: 181 YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS 240
Query: 259 QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ 318
QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ
Sbjct: 241 QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ 300
Query: 319 NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN 378
NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN
Sbjct: 301 NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN 360
Query: 379 RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA 438
RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA
Sbjct: 361 RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA 420
Query: 439 LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP 498
LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP
Sbjct: 421 LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP 480
Query: 499 FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ 558
FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ
Sbjct: 481 FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ 540
Query: 559 HGYGSWIVKSPCIEQFNM 576
HGYGSWIVKSPCIEQFNM
Sbjct: 541 HGYGSWIVKSPCIEQFNM 558
>gi|223972690 adenosine deaminase domain containing 2 isoform 2
[Homo sapiens]
Length = 583
Score = 189 bits (479), Expect = 8e-48
Identities = 155/468 (33%), Positives = 236/468 (50%), Gaps = 44/468 (9%)
Query: 125 GPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPEPRILETSGPPPF 181
GP F F A +DG+ G +K E++ AA AL + QL+ PE +TS PP
Sbjct: 140 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESP--QTSSRPP- 196
Query: 182 PAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIER 241
L+ L+ + + +E R + +V F+ L+ RS Y ++A I+ER
Sbjct: 197 ------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWACKGTVAGVILER 244
Query: 242 ----AGQH-----EVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLF 292
A H ++VA+GTG + ++ G+ LHD H +V ARR+LLR+ +RQLLL
Sbjct: 245 EIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLA 304
Query: 293 YSKNPAMMEKSIFCTEP-TSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE 351
P E+S+ +P TLK + + LY++ PKG+A+ + L P S
Sbjct: 305 TQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAAR---DIYLPPTSEGGLP 361
Query: 352 ANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVY 410
+ + L V G++ Y P + +S+SDKL RW VLG+ GALL+H + P+Y
Sbjct: 362 HSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLY 421
Query: 411 ISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 468
+S+++ D +C D L AI R +D L LP Y+ H+ P P + +
Sbjct: 422 STSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPD 480
Query: 469 -YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKE-AK 526
+ LSLNW+ GD +E+VD +G++ + + + SRLCKA+ L F+ A+ K
Sbjct: 481 TCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGPPSRLCKASFLRAFHQAARAVGK 536
Query: 527 KELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 574
LL TY AAK + YQEA+ +L L Q G G+W K P + +F
Sbjct: 537 PYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAWPSK-PLVGKF 581
>gi|223972688 adenosine deaminase domain containing 2 isoform 1
[Homo sapiens]
Length = 665
Score = 187 bits (474), Expect = 3e-47
Identities = 153/490 (31%), Positives = 240/490 (48%), Gaps = 54/490 (11%)
Query: 113 DLKETVTTGNVMGPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPE 169
+++ + +GP F F A +DG+ G +K E++ AA AL + QL+ PE
Sbjct: 200 EMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPE 259
Query: 170 PRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLK 229
+TS PP L+ L+ + + +E R + +V F+ L+ RS Y
Sbjct: 260 SP--QTSSRPP-------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWA 304
Query: 230 YSSSLAAFIIERAGQ-------------------HEVVAIGTGEYNYSQDIKPDGRVLHD 270
++A I+ER +++VA+GTG + ++ G+ LHD
Sbjct: 305 CKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHD 364
Query: 271 THAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEP-TSNLLTLKQNINICLYMNQL 329
H +V ARR+LLR+ +RQLLL P E+S+ +P TLK + + LY++
Sbjct: 365 CHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNT 424
Query: 330 PKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDK 388
PKG+A+ + L P S + + L V G++ Y P + +S+SDK
Sbjct: 425 PKGAAR---DIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDK 481
Query: 389 LTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMF 446
L RW VLG+ GALL+H + P+Y +S+++ D +C D L AI R +D L LP
Sbjct: 482 LARWAVLGLGGALLAHLVSPLYSTSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540
Query: 447 YLVNRPHISLVPSAYPLQMNLE-YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSM 505
Y+ H+ P P + + + LSLNW+ GD +E+VD +G++ + + +
Sbjct: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGP 596
Query: 506 ASRLCKAAMLSRFNLLAKE-AKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSW 564
SRLCKA+ L F+ A+ K LL TY AAK + YQEA+ +L L Q G G+W
Sbjct: 597 PSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAW 654
Query: 565 IVKSPCIEQF 574
K P + +F
Sbjct: 655 PSK-PLVGKF 663
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 160 bits (404), Expect = 4e-39
Identities = 157/527 (29%), Positives = 245/527 (46%), Gaps = 75/527 (14%)
Query: 75 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 134
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
Query: 135 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 194
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
Query: 195 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 251
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
Query: 252 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPT 310
TG + + D G L+D HA + +RRSLLR+ Y QL L Y N ++SIF
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLEL-YLNNKDDQKRSIFQKSER 431
Query: 311 SNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE---------ANEELCLHV- 360
LK+N+ LY++ P G A+I S PH E A +L +
Sbjct: 432 GGF-RLKENVQFHLYISTSPCGDARIFS-----PHEPILEEPADRHPNRKARGQLRTKIE 485
Query: 361 AVEGKIYLTVYCPK---DGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSI 414
+ EG I + DGV R+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI
Sbjct: 486 SGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSI 545
Query: 415 LIGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSL 474
++G D L A+ QR+ + LP Y +N+P +S + +A Q F S+
Sbjct: 546 ILGSLYHGD--HLSRAMYQRISN--IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SV 600
Query: 475 NWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-- 532
NW GD ++E+++ +G K + ASRLCK A+ R+ + + LL +
Sbjct: 601 NWTVGDSAIEVINATTG--------KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKI 652
Query: 533 ---GTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM 576
YH +K + YQ AK +L + + G G+W+ K +QF++
Sbjct: 653 TKPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSL 699
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 158 bits (400), Expect = 1e-38
Identities = 141/470 (30%), Positives = 219/470 (46%), Gaps = 63/470 (13%)
Query: 128 FAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVV 187
F VDG ++ G G++KK +R AA+ AL EL + P G P A
Sbjct: 306 FVMAVSVDGRTFE-GSGRSKKLARGQAAQAALQELFDIQMP--------GHAPGRARRTP 356
Query: 188 LSELAYVSKVHYEGRHIQYA-KISQIVKERFNQLISNRSEYLKYSSSLAAFIIER---AG 243
+ + ++A ISQ+V ++F ++ ++ + +LA ++ + A
Sbjct: 357 MPQ--------------EFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDAR 402
Query: 244 QHEVVAIGTGEYNYS-QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEK 302
Q +VVA+ +G S + + G V++D HA V ARR+ L + Y QL L SK E+
Sbjct: 403 QAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSER 462
Query: 303 SIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKS------QLRLNPHSISAFEANEEL 356
SIF L++NI LY++ P G A++ S L + H + F +
Sbjct: 463 SIFVRLKEGGY-RLRENILFHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRT 521
Query: 357 CLH-----VAVEGKIYLTVYCPKDGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQP 408
+ V V G + + DGV ++ +MS +DK+ RW VLG+QGALLSHF++P
Sbjct: 522 KIESGEGTVPVRGPSAVQTW---DGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEP 578
Query: 409 VYISSILIGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 468
VY+ SI++ G+ T L + R++ +LP Y NRP +S V A Q
Sbjct: 579 VYLQSIVV--GSLHHTGHLARVMSHRMEG--VGQLPASYRHNRPLLSGVSDAEARQPGKS 634
Query: 469 YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKE 528
F S+NW G LEI++ +G+ + P SRLCK + +R+ L
Sbjct: 635 PPF-SMNWVVGSADLEIINATTGRRSCGGP--------SRLCKHVLSARWARLYGRLSTR 685
Query: 529 LLEAG----TYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 574
G Y AK + +YQ K +L Q+ G G+W+ K P +QF
Sbjct: 686 TPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQF 735
Score = 38.9 bits (89), Expect = 0.013
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 85 EFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLG 144
+ + K + P +AL Q ++ R L + TG V P FA V+G+ ++ G G
Sbjct: 114 QLVWKKLSWSVAPKNALVQLHEL-RPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFE-GTG 171
Query: 145 QNKKESRSNAAKLALDELLQLDEPEPRILETSGPP 179
KK+++ AA+LAL +Q L G P
Sbjct: 172 PTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGP 206
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 147 bits (371), Expect = 3e-35
Identities = 155/562 (27%), Positives = 243/562 (43%), Gaps = 105/562 (18%)
Query: 75 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 134
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
Query: 135 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 194
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
Query: 195 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 251
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
Query: 252 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPT 310
TG + + D G L+D HA + +RRSLLR+ Y QL L Y N ++SIF
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLEL-YLNNKDDQKRSIFQKSER 431
Query: 311 SNLLTLKQNINICLYMNQLP-----------------------------KGSAQIKSQLR 341
LK+N+ LY++ P GS Q +
Sbjct: 432 GGF-RLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGL 490
Query: 342 LNPHSISAFEA---NEELCLHVAVEGKIYLTVYCPK----------------DGV---NR 379
L+ S S F+ E H + + L DGV R
Sbjct: 491 LSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGER 550
Query: 380 ISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDAL 439
+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI++G D L A+ QR+ +
Sbjct: 551 LLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGD--HLSRAMYQRISN-- 606
Query: 440 TSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSPF 499
LP Y +N+P +S + +A Q F S+NW GD ++E+++ +G
Sbjct: 607 IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVNWTVGDSAIEVINATTG-------- 657
Query: 500 KSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-----GTYHAAKCMSASYQEAKCKLKS 554
K + ASRLCK A+ R+ + + LL + YH +K + YQ AK +L +
Sbjct: 658 KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFT 717
Query: 555 YLQQHGYGSWIVKSPCIEQFNM 576
+ G G+W+ K +QF++
Sbjct: 718 AFIKAGLGAWVEKPTEQDQFSL 739
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 147 bits (370), Expect = 3e-35
Identities = 150/500 (30%), Positives = 230/500 (46%), Gaps = 75/500 (15%)
Query: 75 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 134
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
Query: 135 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 194
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
Query: 195 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 251
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
Query: 252 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPT 310
TG + + D G L+D HA + +RRSLLR+ Y QL L Y N ++SIF
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLEL-YLNNKDDQKRSIFQKSER 431
Query: 311 SNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE---------ANEELCLHV- 360
LK+N+ LY++ P G A+I S PH E A +L +
Sbjct: 432 GGF-RLKENVQFHLYISTSPCGDARIFS-----PHEPILEEPADRHPNRKARGQLRTKIE 485
Query: 361 AVEGKIYLTVYCPK---DGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSI 414
+ EG I + DGV R+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI
Sbjct: 486 SGEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSI 545
Query: 415 LIGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSL 474
++G D L A+ QR+ + LP Y +N+P +S + +A Q F S+
Sbjct: 546 ILGSLYHGD--HLSRAMYQRISN--IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SV 600
Query: 475 NWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-- 532
NW GD ++E+++ +G K + ASRLCK A+ R+ + + LL +
Sbjct: 601 NWTVGDSAIEVINATTG--------KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKI 652
Query: 533 ---GTYHAAKCMSASYQEAK 549
YH +K + YQ AK
Sbjct: 653 TKPNVYHESKLAAKEYQAAK 672
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 138 bits (347), Expect = 2e-32
Identities = 140/539 (25%), Positives = 238/539 (44%), Gaps = 62/539 (11%)
Query: 54 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 687 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742
Query: 113 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
+ K +G P F + A V G + +KK+ + AA AL L+ +E
Sbjct: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEK---- 798
Query: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSS 232
AE + +EL ++ +I+ + FN L ++ L
Sbjct: 799 ----------AERMGFTELPLTGSTFHD-------QIAMLSHRCFNTLTNSFQPSLLGRK 841
Query: 233 SLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLRYFYRQL 289
LAA I+++ + VV++GTG D + G ++D HA + +RR +R+ Y +L
Sbjct: 842 ILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSEL 901
Query: 290 LLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI-------KSQLRL 342
+ + S+ + SIF L +K+ ++ LY++ P G + ++
Sbjct: 902 MKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMEST 958
Query: 343 NPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSDKLTRWE 393
FE ++ L VE G I + + DG+ R+ +MS SDK+ RW
Sbjct: 959 ESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWN 1018
Query: 394 VLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKLPMFYLV 449
VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L ++V
Sbjct: 1019 VLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGLRHPFIV 1075
Query: 450 NRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSGMSMASR 508
N P + V + + + K S+NW D LEI+DG G + + SR
Sbjct: 1076 NHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGPRNELSR 1129
Query: 509 LCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVK 567
+ K + F L + L +Y AK + Y+ AK K L+ GYG+WI K
Sbjct: 1130 VSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISK 1188
Score = 33.9 bits (76), Expect = 0.42
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
Query: 156 KLALDELLQ 164
A+ LL+
Sbjct: 563 MKAMTILLE 571
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 136 bits (343), Expect = 5e-32
Identities = 144/545 (26%), Positives = 243/545 (44%), Gaps = 48/545 (8%)
Query: 54 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 392 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 447
Query: 113 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
+ K +G P F + A V G + +KK+ + AA AL L+ +E R+
Sbjct: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507
Query: 173 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 226
T P A ++LS A + G + +I+ + FN L ++
Sbjct: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 566
Query: 227 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLR 283
L LAA I+++ + VV++GTG D + G ++D HA + +RR +R
Sbjct: 567 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 626
Query: 284 YFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI------- 336
+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G +
Sbjct: 627 FLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 683
Query: 337 KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSD 387
++ FE ++ L VE G I + + DG+ R+ +MS SD
Sbjct: 684 RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 743
Query: 388 KLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKL 443
K+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L
Sbjct: 744 KILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGL 800
Query: 444 PMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSG 502
++VN P + V + + + K S+NW D LEI+DG G +
Sbjct: 801 RHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGP 854
Query: 503 MSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYG 562
+ SR+ K + F L + L +Y AK + Y+ AK K L+ GYG
Sbjct: 855 RNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYG 914
Query: 563 SWIVK 567
+WI K
Sbjct: 915 NWISK 919
Score = 33.9 bits (76), Expect = 0.42
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 208 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 267
Query: 156 KLALDELLQ 164
A+ LL+
Sbjct: 268 MKAMTILLE 276
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 136 bits (343), Expect = 5e-32
Identities = 144/545 (26%), Positives = 243/545 (44%), Gaps = 48/545 (8%)
Query: 54 TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
+ + N PE ++S++L ++ + + P K+ K +++Y NPV L ++A+
Sbjct: 687 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742
Query: 113 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
+ K +G P F + A V G + +KK+ + AA AL L+ +E R+
Sbjct: 743 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802
Query: 173 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 226
T P A ++LS A + G + +I+ + FN L ++
Sbjct: 803 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 861
Query: 227 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLR 283
L LAA I+++ + VV++GTG D + G ++D HA + +RR +R
Sbjct: 862 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 921
Query: 284 YFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI------- 336
+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G +
Sbjct: 922 FLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSD 978
Query: 337 KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSD 387
++ FE ++ L VE G I + + DG+ R+ +MS SD
Sbjct: 979 RAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSD 1038
Query: 388 KLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKL 443
K+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + + R A L
Sbjct: 1039 KILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGL 1095
Query: 444 PMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSG 502
++VN P + V + + + K S+NW D LEI+DG G +
Sbjct: 1096 RHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGP 1149
Query: 503 MSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYG 562
+ SR+ K + F L + L +Y AK + Y+ AK K L+ GYG
Sbjct: 1150 RNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYG 1209
Query: 563 SWIVK 567
+WI K
Sbjct: 1210 NWISK 1214
Score = 33.9 bits (76), Expect = 0.42
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
Query: 156 KLALDELLQ 164
A+ LL+
Sbjct: 563 MKAMTILLE 571
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 134 bits (337), Expect = 2e-31
Identities = 148/535 (27%), Positives = 228/535 (42%), Gaps = 105/535 (19%)
Query: 75 PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 134
PVLPP P G+ NPV L++ R L +G F VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269
Query: 135 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 194
DG Q+ G G+NKK +++ AA+ AL + L + +T P P+E + L ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319
Query: 195 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 251
+V + +S++V +F L N S LA ++ +V+++
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372
Query: 252 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPT 310
TG + + D G L+D HA + +RRSLLR+ Y QL L Y N ++SIF
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLEL-YLNNKDDQKRSIFQKSER 431
Query: 311 SNLLTLKQNINICLYMNQLP-----------------------------KGSAQIKSQLR 341
LK+N+ LY++ P GS Q +
Sbjct: 432 GGF-RLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGL 490
Query: 342 LNPHSISAFEA---NEELCLHVAVEGKIYLTVYCPK----------------DGV---NR 379
L+ S S F+ E H + + L DGV R
Sbjct: 491 LSDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGER 550
Query: 380 ISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDAL 439
+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI++G D L A+ QR+ +
Sbjct: 551 LLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGD--HLSRAMYQRISN-- 606
Query: 440 TSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSPF 499
LP Y +N+P +S + +A Q F S+NW GD ++E+++ +G
Sbjct: 607 IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVNWTVGDSAIEVINATTG-------- 657
Query: 500 KSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-----GTYHAAKCMSASYQEAK 549
K + ASRLCK A+ R+ + + LL + YH +K + YQ AK
Sbjct: 658 KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 132 bits (331), Expect = 1e-30
Identities = 131/496 (26%), Positives = 215/496 (43%), Gaps = 57/496 (11%)
Query: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
NPV L ++A+ + K +G P F + A V G + +KK+ + AA
Sbjct: 707 NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 766
Query: 156 KLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKE 215
AL L+ +E AE + +EL ++ +I+ +
Sbjct: 767 DAALRVLIGENEK--------------AERMGFTELPLTGSTFHD-------QIAMLSHR 805
Query: 216 RFNQLISNRSEYLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTH 272
FN L ++ L LAA I+++ + VV++GTG D + G ++D H
Sbjct: 806 CFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCH 865
Query: 273 AVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKG 332
A + +RR +R+ Y +L+ + S+ + SIF L +K+ ++ LY++ P G
Sbjct: 866 AEIISRRGFIRFLYSELMKYNSQTA---KDSIFEPAKGGEKLQIKKTVSFHLYISTAPCG 922
Query: 333 SAQI-------KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN- 378
+ ++ FE ++ L VE G I + + DG+
Sbjct: 923 DGALFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRL 982
Query: 379 --RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIK 432
R+ +MS SDK+ RW VLG+QGALL+HF+QP+Y+ S+ +G G+ TR + +
Sbjct: 983 GERLRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV- 1039
Query: 433 QRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSG 491
R A L ++VN P + V + + + K S+NW D LEI+DG G
Sbjct: 1040 TRDGSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRG 1099
Query: 492 KITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCK 551
+ + SR+ K + F L + L +Y AK + Y+ AK
Sbjct: 1100 TV------DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNY 1153
Query: 552 LKSYLQQHGYGSWIVK 567
K L+ GYG+WI K
Sbjct: 1154 FKKGLKDMGYGNWISK 1169
Score = 33.9 bits (76), Expect = 0.42
Identities = 19/69 (27%), Positives = 34/69 (49%)
Query: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
NP+S L ++AQ + +G P F F V++G ++ +KK ++ +AA
Sbjct: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562
Query: 156 KLALDELLQ 164
A+ LL+
Sbjct: 563 MKAMTILLE 571
>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
Length = 502
Score = 55.5 bits (132), Expect = 1e-07
Identities = 56/220 (25%), Positives = 93/220 (42%), Gaps = 33/220 (15%)
Query: 378 NRISSMSSSDKLTRWEVLGVQGALLSHFI-QPVYISSILIGD-------------GNCSD 423
+R SMS SDK+ RW VLG QGALL H + +P+Y+S+++IG G C +
Sbjct: 292 DRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGRCQN 351
Query: 424 TRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSL 483
L + L S L L + ++ L +++W+ V
Sbjct: 352 VSALPKGFGVQELKILQSDL----LFEQSRSAVQAKRADSPGRLVPCGAAISWSA--VPE 405
Query: 484 EIVDGLSGKITESSPFKS--GMSMASRLCKAAMLSRFNLLAKEAKKE-------LLEAGT 534
+ +D + + + K+ + S++ K + F L ++ + + T
Sbjct: 406 QPLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLSRIARDKWPHSLRVQKLDT 465
Query: 535 YHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 574
Y K ++SYQEA S L++ +GSWI P QF
Sbjct: 466 YQEYKEAASSYQEA----WSTLRKQVFGSWIRNPPDYHQF 501
Score = 46.6 bits (109), Expect = 6e-05
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 5/92 (5%)
Query: 246 EVVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSI 304
E+V++GTG Q ++ +G +L+D+HA V ARRS RY QL L + E SI
Sbjct: 60 EIVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQL----AATLKEDSI 115
Query: 305 FCTEPTSNLLTLKQNINICLYMNQLPKGSAQI 336
F + L++++ + + P G A I
Sbjct: 116 FVPGTQKGVWKLRRDLIFVFFSSHTPCGDASI 147
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/62 (35%), Positives = 37/62 (59%)
Query: 101 LHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALD 160
L+ + Q Q V L +E +G F F ++DG ++ G G++KKE+++ AAKLA++
Sbjct: 14 LNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73
Query: 161 EL 162
L
Sbjct: 74 IL 75
Score = 30.0 bits (66), Expect = 6.0
Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPY-FAFCAVVDGIQYKTGLGQNKKESRSNA 154
N + +++ AQ +R+ ++ ++ + V GP F + + +Y G G K+E++ A
Sbjct: 100 NYIGLINRIAQKKRLTVNYEQCAS--GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLA 157
Query: 155 AKLALDELL 163
AKLA ++L
Sbjct: 158 AKLAYLQIL 166
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/62 (35%), Positives = 37/62 (59%)
Query: 101 LHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALD 160
L+ + Q Q V L +E +G F F ++DG ++ G G++KKE+++ AAKLA++
Sbjct: 14 LNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73
Query: 161 EL 162
L
Sbjct: 74 IL 75
Score = 30.0 bits (66), Expect = 6.0
Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPY-FAFCAVVDGIQYKTGLGQNKKESRSNA 154
N + +++ AQ +R+ ++ ++ + V GP F + + +Y G G K+E++ A
Sbjct: 100 NYIGLINRIAQKKRLTVNYEQCAS--GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLA 157
Query: 155 AKLALDELL 163
AKLA ++L
Sbjct: 158 AKLAYLQIL 166
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/62 (35%), Positives = 37/62 (59%)
Query: 101 LHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALD 160
L+ + Q Q V L +E +G F F ++DG ++ G G++KKE+++ AAKLA++
Sbjct: 14 LNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73
Query: 161 EL 162
L
Sbjct: 74 IL 75
Score = 30.0 bits (66), Expect = 6.0
Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 3/69 (4%)
Query: 96 NPVSALHQFAQMQRVQLDLKETVTTGNVMGPY-FAFCAVVDGIQYKTGLGQNKKESRSNA 154
N + +++ AQ +R+ ++ ++ + V GP F + + +Y G G K+E++ A
Sbjct: 100 NYIGLINRIAQKKRLTVNYEQCAS--GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLA 157
Query: 155 AKLALDELL 163
AKLA ++L
Sbjct: 158 AKLAYLQIL 166
>gi|7657625 staufen homolog 2 [Homo sapiens]
Length = 479
Score = 40.4 bits (93), Expect = 0.004
Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 16 FAQMLKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPEP 63
F LK+N+PV P K+ T +S+E G SK SK T E
Sbjct: 181 FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL 240
Query: 64 LLSKNLSSISNPVLPPKKIPKEFIM---KYKRGEINPVSALHQFAQMQRVQLDLKETVTT 120
L + P L KK PK + +Y +G +NP+S L Q Q ++ + ++
Sbjct: 241 KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQG-MNPISRLAQIQQAKKEKEPDYVLLSE 299
Query: 121 GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDEL 162
+ V G + TG G NKK ++ NAA+ L +L
Sbjct: 300 RGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQL 341
>gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens]
Length = 1066
Score = 35.8 bits (81), Expect = 0.11
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 15/110 (13%)
Query: 8 FQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSK 67
F++++ P Q+L++ P TK T P+ S++ TQ F +
Sbjct: 324 FKTAKEPIVVQVLRRT----PRTKMFTPPSE--------SQLVDTGTQTDITFEHIMALT 371
Query: 68 NLSSISNPVLPPKKIPKEFIMKYKRGEINP-VSALHQFAQMQRVQLDLKE 116
+SS S PVL P +P+E ++ + N + +HQ +M R +L+L+E
Sbjct: 372 KMSSPSPPVLDPYLLPEEHPSAHEYYDPNDYIGDIHQ--EMDREELELEE 419
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 35.4 bits (80), Expect = 0.14
Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 41/214 (19%)
Query: 16 FAQMLKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE- 62
F LK+NLPV P K T + E G SK SK E
Sbjct: 109 FEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL 168
Query: 63 ----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLD 113
PL + + + P++ P+ P+ Y +G INP+S L Q Q ++ + +
Sbjct: 169 KKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKE 221
Query: 114 LKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
+ T+ T + F V G G G NKK ++ NAA+ L+ I
Sbjct: 222 PEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------I 270
Query: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 206
L P P +P + SE K +GR + +
Sbjct: 271 LGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 304
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 35.4 bits (80), Expect = 0.14
Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 41/214 (19%)
Query: 16 FAQMLKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE- 62
F LK+NLPV P K T + E G SK SK E
Sbjct: 190 FEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL 249
Query: 63 ----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLD 113
PL + + + P++ P+ P+ Y +G INP+S L Q Q ++ + +
Sbjct: 250 KKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKE 302
Query: 114 LKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
+ T+ T + F V G G G NKK ++ NAA+ L+ I
Sbjct: 303 PEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------I 351
Query: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 206
L P P +P + SE K +GR + +
Sbjct: 352 LGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 385
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 35.4 bits (80), Expect = 0.14
Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 41/214 (19%)
Query: 16 FAQMLKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE- 62
F LK+NLPV P K T + E G SK SK E
Sbjct: 109 FEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL 168
Query: 63 ----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLD 113
PL + + + P++ P+ P+ Y +G INP+S L Q Q ++ + +
Sbjct: 169 KKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKE 221
Query: 114 LKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
+ T+ T + F V G G G NKK ++ NAA+ L+ I
Sbjct: 222 PEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------I 270
Query: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 206
L P P +P + SE K +GR + +
Sbjct: 271 LGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 304
>gi|82659083 staufen isoform a [Homo sapiens]
Length = 496
Score = 35.4 bits (80), Expect = 0.14
Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 41/214 (19%)
Query: 16 FAQMLKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE- 62
F LK+NLPV P K T + E G SK SK E
Sbjct: 109 FEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL 168
Query: 63 ----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLD 113
PL + + + P++ P+ P+ Y +G INP+S L Q Q ++ + +
Sbjct: 169 KKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKE 221
Query: 114 LKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
+ T+ T + F V G G G NKK ++ NAA+ L+ I
Sbjct: 222 PEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------I 270
Query: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 206
L P P +P + SE K +GR + +
Sbjct: 271 LGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 304
>gi|82659091 staufen isoform c [Homo sapiens]
Length = 502
Score = 33.1 bits (74), Expect = 0.71
Identities = 55/220 (25%), Positives = 82/220 (37%), Gaps = 47/220 (21%)
Query: 16 FAQMLKKNLPVQ---------------PATKTITTPTG---WSSESYGLSKMASKVTQVT 57
F LK+NLPV P K T + E G SK SK
Sbjct: 109 FEIALKRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAI 168
Query: 58 GNFPE-----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQM 107
E PL + + + P++ P+ P+ Y +G INP+S L Q Q
Sbjct: 169 AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQA 222
Query: 108 QRVQLDLKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLD 166
++ + + + T+ T + F V G G G NKK ++ NAA+ L+
Sbjct: 223 KK-EKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE------ 275
Query: 167 EPEPRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 206
IL P P +P + SE K +GR + +
Sbjct: 276 -----ILGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 310
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 32.0 bits (71), Expect = 1.6
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 16/175 (9%)
Query: 21 KKNLPVQPATKTITT---PTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVL 77
KK + A K + PTG + +++ T+ P S +
Sbjct: 450 KKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAF 509
Query: 78 PPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGI 137
P ++ + K G+ NPV L++ +R L + TG F VDG
Sbjct: 510 PSDATAEQGPILTKHGK-NPVMELNE----KRRGLKYELISETGGSHDKRFVMEVEVDGQ 564
Query: 138 QYKTGLGQNKKESRSNAAKLALDEL-------LQLDEPEPRILETSGPPPFPAEP 185
+++ G G NKK +++ AA AL++L L ++ + + G P F A+P
Sbjct: 565 KFQ-GAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKP 618
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 32.0 bits (71), Expect = 1.6
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 16/175 (9%)
Query: 21 KKNLPVQPATKTITT---PTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVL 77
KK + A K + PTG + +++ T+ P S +
Sbjct: 450 KKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAF 509
Query: 78 PPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGI 137
P ++ + K G+ NPV L++ +R L + TG F VDG
Sbjct: 510 PSDATAEQGPILTKHGK-NPVMELNE----KRRGLKYELISETGGSHDKRFVMEVEVDGQ 564
Query: 138 QYKTGLGQNKKESRSNAAKLALDEL-------LQLDEPEPRILETSGPPPFPAEP 185
+++ G G NKK +++ AA AL++L L ++ + + G P F A+P
Sbjct: 565 KFQ-GAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKP 618
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 32.0 bits (71), Expect = 1.6
Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 16/175 (9%)
Query: 21 KKNLPVQPATKTITT---PTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVL 77
KK + A K + PTG + +++ T+ P S +
Sbjct: 450 KKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAF 509
Query: 78 PPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGI 137
P ++ + K G+ NPV L++ +R L + TG F VDG
Sbjct: 510 PSDATAEQGPILTKHGK-NPVMELNE----KRRGLKYELISETGGSHDKRFVMEVEVDGQ 564
Query: 138 QYKTGLGQNKKESRSNAAKLALDEL-------LQLDEPEPRILETSGPPPFPAEP 185
+++ G G NKK +++ AA AL++L L ++ + + G P F A+P
Sbjct: 565 KFQ-GAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKP 618
>gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens]
Length = 1042
Score = 32.0 bits (71), Expect = 1.6
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 174 ETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVK------ERFNQLISNRSEY 227
+ G P A V L+EL + HY G Y I + +K E +LI N+S +
Sbjct: 363 KNDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQSAW 422
Query: 228 LKYSSSLAAFIIERAGQHEVVAIG 251
S+SLA+ + +G+ E G
Sbjct: 423 TSQSNSLASCLSRLSGKSETGKTG 446
>gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens]
Length = 1726
Score = 31.6 bits (70), Expect = 2.1
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 4/69 (5%)
Query: 25 PVQPAT-KTITTPTGWSSESYGLSKMASKVTQVTGNFPEPL---LSKNLSSISNPVLPPK 80
P PA K +TTPT + +++ K Q TG L L + S++N PK
Sbjct: 518 PTNPAAQKALTTPTHYKLTPRPATRVRPKALQTTGTAKSHLFDGLDDDEPSLANGAFMPK 577
Query: 81 KIPKEFIMK 89
K K+ ++K
Sbjct: 578 KSIKKLVLK 586
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,292,717
Number of Sequences: 37866
Number of extensions: 929019
Number of successful extensions: 2417
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 2330
Number of HSP's gapped (non-prelim): 67
length of query: 576
length of database: 18,247,518
effective HSP length: 108
effective length of query: 468
effective length of database: 14,157,990
effective search space: 6625939320
effective search space used: 6625939320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.