Search of human proteins with 212275945

Search of human proteins with 212275945

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|212275945 male-specific lethal 3-like 1 isoform a [Homo
sapiens]
         (521 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|212275945 male-specific lethal 3-like 1 isoform a [Homo sapiens]  1056   0.0  
gi|17975759 male-specific lethal 3-like 1 isoform b [Homo sapiens]    930   0.0  
gi|17975755 male-specific lethal 3-like 1 isoform d [Homo sapiens]    787   0.0  
gi|17975761 male-specific lethal 3-like 1 isoform c [Homo sapiens]    723   0.0  
gi|5803102 MORF-related gene 15 isoform 1 [Homo sapiens]              102   7e-22
gi|45643135 MORF-related gene 15 isoform 2 [Homo sapiens]              85   2e-16
gi|215490049 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490047 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490045 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490043 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490041 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490039 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490037 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490035 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490033 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490031 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490029 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490027 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490025 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490023 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|215490021 mortality factor 4 like 2 [Homo sapiens]                  51   3e-06
gi|6912448 mortality factor 4 like 2 [Homo sapiens]                    51   3e-06
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ...    49   1e-05
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s...    49   1e-05
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa...    49   1e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    47   6e-05
gi|6996928 mortality factor 4 [Homo sapiens]                           45   1e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        45   2e-04
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    45   2e-04
gi|215422388 death-domain associated protein isoform a [Homo sap...    45   2e-04

>gi|212275945 male-specific lethal 3-like 1 isoform a [Homo sapiens]
          Length = 521

 Score = 1056 bits (2732), Expect = 0.0
 Identities = 521/521 (100%), Positives = 521/521 (100%)

Query: 1   MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWN 60
           MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWN
Sbjct: 1   MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWN 60

Query: 61  RSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEE 120
           RSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEE
Sbjct: 61  RSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEE 120

Query: 121 KDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVL 180
           KDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVL
Sbjct: 121 KDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVL 180

Query: 181 KKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANM 240
           KKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANM
Sbjct: 181 KKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANM 240

Query: 241 NVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATS 300
           NVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATS
Sbjct: 241 NVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATS 300

Query: 301 TNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDR 360
           TNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDR
Sbjct: 301 TNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDR 360

Query: 361 LSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGR 420
           LSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGR
Sbjct: 361 LSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGR 420

Query: 421 RTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKAL 480
           RTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKAL
Sbjct: 421 RTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKAL 480

Query: 481 LKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY 521
           LKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY
Sbjct: 481 LKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY 521


>gi|17975759 male-specific lethal 3-like 1 isoform b [Homo sapiens]
          Length = 462

 Score =  930 bits (2404), Expect = 0.0
 Identities = 460/460 (100%), Positives = 460/460 (100%)

Query: 62  SWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEK 121
           SWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEK
Sbjct: 3   SWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEK 62

Query: 122 DENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLK 181
           DENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLK
Sbjct: 63  DENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLK 122

Query: 182 KQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMN 241
           KQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMN
Sbjct: 123 KQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMN 182

Query: 242 VHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATST 301
           VHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATST
Sbjct: 183 VHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATST 242

Query: 302 NRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDRL 361
           NRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDRL
Sbjct: 243 NRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDRL 302

Query: 362 SESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRR 421
           SESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRR
Sbjct: 303 SESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRR 362

Query: 422 TNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALL 481
           TNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALL
Sbjct: 363 TNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALL 422

Query: 482 KHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY 521
           KHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY
Sbjct: 423 KHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY 462


>gi|17975755 male-specific lethal 3-like 1 isoform d [Homo sapiens]
          Length = 416

 Score =  787 bits (2032), Expect = 0.0
 Identities = 390/390 (100%), Positives = 390/390 (100%)

Query: 1   MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWN 60
           MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWN
Sbjct: 1   MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWN 60

Query: 61  RSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEE 120
           RSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEE
Sbjct: 61  RSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEE 120

Query: 121 KDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVL 180
           KDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVL
Sbjct: 121 KDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVL 180

Query: 181 KKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANM 240
           KKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANM
Sbjct: 181 KKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANM 240

Query: 241 NVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATS 300
           NVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATS
Sbjct: 241 NVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKESATS 300

Query: 301 TNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDR 360
           TNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDR
Sbjct: 301 TNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSANCDR 360

Query: 361 LSESSASPQPKRRQQDTSASMPKLFLHLEK 390
           LSESSASPQPKRRQQDTSASMPKLFLHLEK
Sbjct: 361 LSESSASPQPKRRQQDTSASMPKLFLHLEK 390


>gi|17975761 male-specific lethal 3-like 1 isoform c [Homo sapiens]
          Length = 355

 Score =  723 bits (1865), Expect = 0.0
 Identities = 355/355 (100%), Positives = 355/355 (100%)

Query: 167 MEERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSAN 226
           MEERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSAN
Sbjct: 1   MEERTITIEIPEVLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSAN 60

Query: 227 ERPRHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVT 286
           ERPRHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVT
Sbjct: 61  ERPRHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVT 120

Query: 287 SSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQ 346
           SSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQ
Sbjct: 121 SSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQ 180

Query: 347 SLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTP 406
           SLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTP
Sbjct: 181 SLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTP 240

Query: 407 SKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEI 466
           SKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEI
Sbjct: 241 SKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPPSYIYGAQHLLRLFVKLPEI 300

Query: 467 LGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY 521
           LGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY
Sbjct: 301 LGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAYVAACEAHYSTKNPRAIY 355


>gi|5803102 MORF-related gene 15 isoform 1 [Homo sapiens]
          Length = 323

 Score =  102 bits (255), Expect = 7e-22
 Identities = 84/302 (27%), Positives = 131/302 (43%), Gaps = 52/302 (17%)

Query: 1   MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWN 60
           M+  +  K KF  GE+VLCF        +LY+AK V V + KD++ +    Y IH++GWN
Sbjct: 1   MAPKQDPKPKFQEGERVLCFH-----GPLLYEAKCVKVAI-KDKQVK----YFIHYSGWN 50

Query: 61  RSWDRWAAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPG-VDSVLKGLPTE 119
           ++WD W  E  VL+  D N + QR+L +   A        K R   PG   S L+    E
Sbjct: 51  KNWDEWVPESRVLKYVDTNLQKQRELQK---ANQEQYAEGKMRGAAPGKKTSGLQQKNVE 107

Query: 120 EKDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPE 178
            K + ++     + D         SE      K   + +P ++       R  + ++IPE
Sbjct: 108 VKTKKNKQKTPGNGDGGST-----SETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPE 162

Query: 179 VLKKQLEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHA 238
            LK  L DD   I R+K+L  LP + N+ +ILE Y                         
Sbjct: 163 ELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDY------------------------- 197

Query: 239 NMNVHYIPAEKNVD----LCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPI 294
               +Y  +  N D       E+V G++  F+  L   LLY +E+ QY ++ +     P+
Sbjct: 198 ---ANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPM 254

Query: 295 KE 296
            +
Sbjct: 255 SQ 256



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 31/72 (43%), Positives = 40/72 (55%), Gaps = 2/72 (2%)

Query: 442 DQPPPP-SYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFP 500
           D P  P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F 
Sbjct: 248 DHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFS 307

Query: 501 ESAY-VAACEAH 511
            S Y VA  E H
Sbjct: 308 ASDYEVAPPEYH 319


>gi|45643135 MORF-related gene 15 isoform 2 [Homo sapiens]
          Length = 362

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 85/341 (24%), Positives = 131/341 (38%), Gaps = 91/341 (26%)

Query: 1   MSASEGMKFKFHSGEKVLCFEPDPTKARVLYDAKIVDVIVGKDEKGRKIPEYLIHFNGWN 60
           M+  +  K KF  GE+VLCF        +LY+AK V V + KD++ +    Y IH++GWN
Sbjct: 1   MAPKQDPKPKFQEGERVLCFH-----GPLLYEAKCVKVAI-KDKQVK----YFIHYSGWN 50

Query: 61  R---------------------------------------SWDRWAAEDHVLRDTDENRR 81
           +                                       SWD W  E  VL+  D N +
Sbjct: 51  KKSAVRPRRSEKSLKTHEDIVALFPVPEGAPSVHHPLLTSSWDEWVPESRVLKYVDTNLQ 110

Query: 82  LQRKLARKAVARLRSTGRKKKRCRLPGVD-SVLKGLPTEEKDENDENSLSSSSDCSENKD 140
            QR+L +   A        K R   PG   S L+    E K + ++     + D      
Sbjct: 111 KQRELQK---ANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGST-- 165

Query: 141 EEISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQLEDDCYYINRRKRLVK 199
              SE      K   + +P ++       R  + ++IPE LK  L DD   I R+K+L  
Sbjct: 166 ---SETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFY 222

Query: 200 LPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVHYIPAEKNVD----LCK 255
           LP + N+ +ILE Y                             +Y  +  N D       
Sbjct: 223 LPAKKNVDSILEDY----------------------------ANYKKSRGNTDNKEYAVN 254

Query: 256 EMVDGLRITFDYTLPLVLLYPYEQAQYKKVTSSKFFLPIKE 296
           E+V G++  F+  L   LLY +E+ QY ++ +     P+ +
Sbjct: 255 EVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQ 295



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 31/72 (43%), Positives = 40/72 (55%), Gaps = 2/72 (2%)

Query: 442 DQPPPP-SYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFP 500
           D P  P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F 
Sbjct: 287 DHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFS 346

Query: 501 ESAY-VAACEAH 511
            S Y VA  E H
Sbjct: 347 ASDYEVAPPEYH 358


>gi|215490049 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490047 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490045 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490043 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490041 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490039 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490037 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490035 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490033 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490031 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490029 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490027 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490025 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490023 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|215490021 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|6912448 mortality factor 4 like 2 [Homo sapiens]
          Length = 288

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/67 (43%), Positives = 39/67 (58%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YGA HLLRLFV++  +L      EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 218 PMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYK 277

Query: 505 VAACEAH 511
           VA+ E H
Sbjct: 278 VASAEYH 284



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 48/222 (21%), Positives = 86/222 (38%), Gaps = 30/222 (13%)

Query: 67  AAEDHVLRDTDENRRLQRKLARKAVARLRSTGRKKKRCRLPGVDSVLKGLPTEEKDENDE 126
           A E++  + T  N  +QR   R A +  ++ G ++K    P +     G   E       
Sbjct: 16  AEEENFKKPTRSN--MQRSKMRGASSGKKTAGPQQKNLE-PALPGRWGGRSAENPPSGSV 72

Query: 127 NSLSSSSDCSENKDE--EISEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQ 183
                +   +    +    SE      K   + +P +++    + R  + ++IPE LK  
Sbjct: 73  RKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARADPTVESEEAFKNRMEVKVKIPEELKPW 132

Query: 184 LEDDCYYINRRKRLVKLPCQTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVH 243
           L +D   + R+K+L +LP + N+  ILE Y                        AN    
Sbjct: 133 LVEDWDLVTRQKQLFQLPAKKNVDAILEEY------------------------ANCKKS 168

Query: 244 YIPAEKNVDLCKEMVDGLRITFDYTLPLVLLYPYEQAQYKKV 285
               +       E+V G++  F+  L   LLY +E+ QY ++
Sbjct: 169 QGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEI 210


>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
           sapiens]
          Length = 1188

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 16/175 (9%)

Query: 25  TKARVLYDAKIVDVIVGKDEKGRKIPE----YLIHFNGWNRSWDRWAAEDHVLRDTDEN- 79
           TK +V Y       I     K  +I +    YL+H+ GWN  +D W   D ++   D+  
Sbjct: 577 TKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGG 636

Query: 80  -RRLQRKLARKAVARLRSTGR-----KKKRCRLPGVDSVLKGLPTE-EKDENDENSLSSS 132
            ++ Q+K A+      +   R     K KR R P   ++   +P    K  N E    S 
Sbjct: 637 PKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSC 696

Query: 133 SDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLKKQLEDD 187
           S  S+++ E+  E++ I E+  +K+  EL+    + +  +  E P++    L+++
Sbjct: 697 S--SDSETEDALEKNLINEELSLKD--ELEKNENLNDDKLDEENPKISAHILKEN 747


>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
           sapiens]
          Length = 1203

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 16/175 (9%)

Query: 25  TKARVLYDAKIVDVIVGKDEKGRKIPE----YLIHFNGWNRSWDRWAAEDHVLRDTDEN- 79
           TK +V Y       I     K  +I +    YL+H+ GWN  +D W   D ++   D+  
Sbjct: 577 TKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGG 636

Query: 80  -RRLQRKLARKAVARLRSTGR-----KKKRCRLPGVDSVLKGLPTE-EKDENDENSLSSS 132
            ++ Q+K A+      +   R     K KR R P   ++   +P    K  N E    S 
Sbjct: 637 PKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSC 696

Query: 133 SDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLKKQLEDD 187
           S  S+++ E+  E++ I E+  +K+  EL+    + +  +  E P++    L+++
Sbjct: 697 S--SDSETEDALEKNLINEELSLKD--ELEKNENLNDDKLDEENPKISAHILKEN 747


>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
           sapiens]
          Length = 1257

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 43/175 (24%), Positives = 78/175 (44%), Gaps = 16/175 (9%)

Query: 25  TKARVLYDAKIVDVIVGKDEKGRKIPE----YLIHFNGWNRSWDRWAAEDHVLRDTDEN- 79
           TK +V Y       I     K  +I +    YL+H+ GWN  +D W   D ++   D+  
Sbjct: 577 TKVKVKYGRGKTQKIYEASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGG 636

Query: 80  -RRLQRKLARKAVARLRSTGR-----KKKRCRLPGVDSVLKGLPTE-EKDENDENSLSSS 132
            ++ Q+K A+      +   R     K KR R P   ++   +P    K  N E    S 
Sbjct: 637 PKKKQKKKAKNKEDSEKDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSC 696

Query: 133 SDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLKKQLEDD 187
           S  S+++ E+  E++ I E+  +K+  EL+    + +  +  E P++    L+++
Sbjct: 697 S--SDSETEDALEKNLINEELSLKD--ELEKNENLNDDKLDEENPKISAHILKEN 747


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 30/162 (18%)

Query: 306  EELSPSPPLLNPSTPQ-------STESQPTTG------EPATPKRRKAE------PEALQ 346
            EE +P PP L P+ P          E +P  G      EP T + R A+      PEAL 
Sbjct: 973  EEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032

Query: 347  SLRRSTRHSANCDRLSES-SASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLT 405
            S           +R  ES +A P P+   ++  ++ P L   LE++T   S    P P T
Sbjct: 1033 S-------QGEVEREGESPAAGPPPQELVEEEPSAPPTL---LEEETEDGSDKVQPPPET 1082

Query: 406  PSKEGSAVFAGFEGRRTNEINEVLSWKLVPDNYPPGDQPPPP 447
            P++E        E  +  E ++  +      + PP D+ PPP
Sbjct: 1083 PAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPP 1124



 Score = 33.9 bits (76), Expect = 0.37
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 119 EEKDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPE 178
           EE++E +E       +  E +D E  EE D EE  E +EE E +   E EE    +E  E
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFE-EEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946

Query: 179 VLKKQLEDD 187
             + + E++
Sbjct: 947 EEEDEEEEE 955



 Score = 33.1 bits (74), Expect = 0.63
 Identities = 22/62 (35%), Positives = 32/62 (51%), Gaps = 2/62 (3%)

Query: 119 EEKDENDENSL-SSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIP 177
           EE++E +E        D  E  +EE  EE + EE+ E +EE EL+   E E+     E+ 
Sbjct: 900 EEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFE-EEEGELEEEEEEEDEEEEEELE 958

Query: 178 EV 179
           EV
Sbjct: 959 EV 960



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 16/52 (30%), Positives = 30/52 (57%), Gaps = 1/52 (1%)

Query: 119 EEKDENDENSLSSSSDCSENKDEEISEES-DIEEKTEVKEEPELQTRREMEE 169
           EE++E++E       +  E  +EE  EE  ++EE+ E ++E E +   E+E+
Sbjct: 911 EEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 21/69 (30%), Positives = 33/69 (47%)

Query: 115 GLPTEEKDENDENSLSSSSDCSENKDEEISEESDIEEKTEVKEEPELQTRREMEERTITI 174
           G P  E+D    N  SS  +  E ++EE  EE + EE+ + +EE E +     EE     
Sbjct: 870 GPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE 929

Query: 175 EIPEVLKKQ 183
           E  E  +++
Sbjct: 930 EFEEEFEEE 938



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 16/50 (32%), Positives = 26/50 (52%)

Query: 138 NKDEEISEESDIEEKTEVKEEPELQTRREMEERTITIEIPEVLKKQLEDD 187
           + DEE  EE + EE+ E +EE E     E E+     E  E  +++ E++
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934


>gi|6996928 mortality factor 4 [Homo sapiens]
          Length = 235

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 25/143 (17%)

Query: 144 SEESDIEEKTEVKEEPELQTRREMEERT-ITIEIPEVLKKQLEDDCYYINRRKRLVKLPC 202
           SE      K   + +P ++       R  + ++IPE LK  L DD   I R+K+L  LP 
Sbjct: 39  SETPQPPRKKRAQVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPA 98

Query: 203 QTNIITILESYVKHFAINAAFSANERPRHHHVMPHANMNVHYIPAEKNVDLCKEMVDGLR 262
           + N+ +ILE Y           AN +  H +              +       E+V G++
Sbjct: 99  EKNVDSILEDY-----------ANYKKSHGN-------------TDNKEYAVNEVVAGIK 134

Query: 263 ITFDYTLPLVLLYPYEQAQYKKV 285
             F+  L   LL  +E+ QY ++
Sbjct: 135 EYFNLMLGTQLLNKFERPQYAEI 157



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)

Query: 446 PPSYIYGAQHLLRLFVKLPEILGKMSFSEKNLKALLKHFDLFLRFLAEYHDDFFPESAY- 504
           P S +YG  HLLRL V++  +L     +EK+L  LL +   FL++LA+     F  S Y 
Sbjct: 165 PMSQVYGVPHLLRLSVQIGAMLAYTPLNEKSLALLLNYLHDFLKYLAKNSATLFSASDYE 224

Query: 505 VAACEAH 511
           VA  E H
Sbjct: 225 VALPEYH 231


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 5/116 (4%)

Query: 293 PIKESATSTNRSQEELSPSPPLLNPSTPQ--STESQPTTGEPATPKRR---KAEPEALQS 347
           P ++S T + +S    SP P + + + P+  S  S     +  TP+RR   ++ P+    
Sbjct: 823 PKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELK 882

Query: 348 LRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIP 403
            R  +RHS +        +S  P++    +S+  PK+   +  +   HS SSSP P
Sbjct: 883 SRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSP 938



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 7/117 (5%)

Query: 299  TSTNRSQEELSPSPPLLNPSTPQ-STESQPTTGEPATPKRRKAEPEALQSLRRSTRHSAN 357
            TS  RS+   SP+P   + S    +T  +  +  P   +RR     +  S RRS   ++ 
Sbjct: 1847 TSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSV 1906

Query: 358  CDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPV---HSRSSSPIPLTPSKEGS 411
              R S S ASP  +RR +  S + P        +TP     SRS +P P+T  +  S
Sbjct: 1907 TRRRSRSRASPVSRRRSR--SRTPPVTRRRSRSRTPTTRRRSRSRTP-PVTRRRSRS 1960



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 5/112 (4%)

Query: 297  SATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEP-EALQSLRRSTRHS 355
            S++S++ S    S SP    P  PQ+     +  +P   +RR   P + + SLR S   S
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPG-PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLS 2692

Query: 356  ANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSR---SSSPIPL 404
             +       S  P P+ +Q  +S    +     + ++P H R   + SP P+
Sbjct: 2693 YSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPM 2744



 Score = 33.1 bits (74), Expect = 0.63
 Identities = 28/112 (25%), Positives = 44/112 (39%), Gaps = 8/112 (7%)

Query: 297  SATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSA 356
            S T T R +   S +PP+    +   T        P T +R ++    +   R  +R S 
Sbjct: 1937 SRTPTTRRRSR-SRTPPVTRRRSRSRTP-------PVTRRRSRSRTSPITRRRSRSRTSP 1988

Query: 357  NCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSK 408
               R S S  SP  +RR +  ++ + +          +  RS S  PL P K
Sbjct: 1989 VTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRK 2040



 Score = 32.7 bits (73), Expect = 0.83
 Identities = 35/135 (25%), Positives = 60/135 (44%), Gaps = 24/135 (17%)

Query: 297 SATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEALQSLRRSTRHSA 356
           S +S+ R  +  +      + S+P+  +S+ ++    +    +++ ++  SLRRS   S+
Sbjct: 724 SGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSS 783

Query: 357 NCDRLSES-------SASPQPK-------RRQQDTSASMPKLFLHLEKKTPVHS--RSSS 400
            C +           S S QPK       RR + +S+  PK     + KTP      SSS
Sbjct: 784 PCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPK----QKSKTPSRQSHSSSS 839

Query: 401 PIPL----TPSKEGS 411
           P P     TP ++GS
Sbjct: 840 PHPKVKSGTPPRQGS 854



 Score = 32.7 bits (73), Expect = 0.83
 Identities = 38/132 (28%), Positives = 56/132 (42%), Gaps = 18/132 (13%)

Query: 286  TSSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTGEPATPKRRKAEPEAL 345
            +SSK   P  E ++ST     E SP  P  + +  + + S P   EP T  R      + 
Sbjct: 1640 SSSKGRGPSPEGSSST-----ESSPEHPPKSRTARRGSRSSP---EPKTKSRTPPRRRSS 1691

Query: 346  QSLRRSTRHSANCDRLSESSASPQ-----PKRRQQDTSASMPKLFLHLEKKTPVHSR--S 398
            +S    TR +    R   +S+SP+     P R ++  S S P+     EK      R  +
Sbjct: 1692 RSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPE---PAEKSRSSRRRRSA 1748

Query: 399  SSPIPLTPSKEG 410
            SSP   T S+ G
Sbjct: 1749 SSPRTKTTSRRG 1760



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 34/140 (24%), Positives = 51/140 (36%), Gaps = 5/140 (3%)

Query: 271  LVLLYPYEQAQYKKVTSSKFFLPIKESATSTNRSQEELSPSPPLLNPSTPQSTESQPTTG 330
            L  L P ++ +    +SS        S++S++ S    S S    + S   S   QP   
Sbjct: 2521 LAALQPAKERRSSSSSSSS-----SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA 2575

Query: 331  EPATPKRRKAEPEALQSLRRSTRHSANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEK 390
                P    A  EA++  R      A   R S SS+S         +S+S          
Sbjct: 2576 LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635

Query: 391  KTPVHSRSSSPIPLTPSKEG 410
             +   S SSS    +P+K G
Sbjct: 2636 SSSSSSSSSSSSSPSPAKPG 2655



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 30/141 (21%), Positives = 52/141 (36%), Gaps = 5/141 (3%)

Query: 316 NPSTPQSTESQPTTGEPATPK-RRKAEPEALQSLRRSTRHSANCDRLSESSASPQPKRRQ 374
           +P++ +  E      EP T   +R + PE       S     + D+  +S+  P P   +
Sbjct: 297 SPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPER 356

Query: 375 QDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKEGSAVFAGFEGRRTNEINEVLSWKLV 434
             T    P     L ++   H  S  P+  TP  +   V    E   T + +   S + +
Sbjct: 357 SSTGPEPPAPTPLLAER---HGGSPQPLATTPLSQ-EPVNPPSEASPTRDRSPPKSPEKL 412

Query: 435 PDNYPPGDQPPPPSYIYGAQH 455
           P +      PP P     ++H
Sbjct: 413 PQSSSSESSPPSPQPTKVSRH 433



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 9/114 (7%)

Query: 297  SATSTNRSQEELSPSPPLLNPSTPQSTESQPTTG-EPATPKRRKAEPEALQSLRRSTRHS 355
            S++S+  S  +   S   + P         PT   + A  + R  EP   +  RRS+  S
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSS 2611

Query: 356  ANCDRLSESSASPQPKRRQQDTSASMPKLFLHLEKKTPVHSRSSSPIPLTPSKE 409
            ++    S SS+S         +S+S           +   S SSSP P  P  +
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSS--------SSSSSSSSSSSSPSPAKPGPQ 2657


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 41/115 (35%), Positives = 53/115 (46%), Gaps = 12/115 (10%)

Query: 67  AAEDHVL-RDTDENR-----RLQRKLARKAVARLRSTG--RKKKRCRLPGVDSVLKGLPT 118
           A  D VL R   ENR     RL   +++ A+ + +S    RKK+R RL G  S     P 
Sbjct: 351 ALSDPVLARRLRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPE 410

Query: 119 EEKDENDENSLSSSSDCSE----NKDEEISEESDIEEKTEVKEEPELQTRREMEE 169
              D  +  S  +S  C        D+E  EESD EE+ E +EE E  T  E EE
Sbjct: 411 ASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEE 465


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 41/115 (35%), Positives = 53/115 (46%), Gaps = 12/115 (10%)

Query: 67  AAEDHVL-RDTDENR-----RLQRKLARKAVARLRSTG--RKKKRCRLPGVDSVLKGLPT 118
           A  D VL R   ENR     RL   +++ A+ + +S    RKK+R RL G  S     P 
Sbjct: 351 ALSDPVLARRLRENRSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPE 410

Query: 119 EEKDENDENSLSSSSDCSE----NKDEEISEESDIEEKTEVKEEPELQTRREMEE 169
              D  +  S  +S  C        D+E  EESD EE+ E +EE E  T  E EE
Sbjct: 411 ASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEE 465


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,338,135
Number of Sequences: 37866
Number of extensions: 1162829
Number of successful extensions: 10973
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 180
Number of HSP's successfully gapped in prelim test: 440
Number of HSP's that attempted gapping in prelim test: 7953
Number of HSP's gapped (non-prelim): 2458
length of query: 521
length of database: 18,247,518
effective HSP length: 107
effective length of query: 414
effective length of database: 14,195,856
effective search space: 5877084384
effective search space used: 5877084384
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.