Guide to the Human Genome
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Search of human proteins with 211059429

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|211059429 synaptotagmin II [Homo sapiens]
         (419 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|211059429 synaptotagmin II [Homo sapiens]                          854   0.0  
gi|31543670 synaptotagmin II [Homo sapiens]                           854   0.0  
gi|209447073 synaptotagmin I [Homo sapiens]                           649   0.0  
gi|5032139 synaptotagmin I [Homo sapiens]                             649   0.0  
gi|209447070 synaptotagmin I [Homo sapiens]                           649   0.0  
gi|92859638 synaptotagmin V [Homo sapiens]                            481   e-136
gi|45504376 synaptotagmin VI [Homo sapiens]                           295   4e-80
gi|94536846 synaptotagmin VIII [Homo sapiens]                         295   7e-80
gi|38570146 synaptotagmin VII [Homo sapiens]                          294   1e-79
gi|39752671 synaptotagmin X [Homo sapiens]                            285   5e-77
gi|238550198 synaptotagmin III [Homo sapiens]                         283   3e-76
gi|238550196 synaptotagmin III [Homo sapiens]                         283   3e-76
gi|14150054 synaptotagmin III [Homo sapiens]                          283   3e-76
gi|28376627 synaptotagmin IX [Homo sapiens]                           281   8e-76
gi|216548478 synaptotagmin XI [Homo sapiens]                          231   9e-61
gi|24308219 synaptotagmin IV [Homo sapiens]                           227   1e-59
gi|40068038 B/K protein [Homo sapiens]                                222   4e-58
gi|6005997 double C2-like domains, beta [Homo sapiens]                186   3e-47
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                 174   1e-43
gi|47078261 double C2-like domains, alpha [Homo sapiens]              170   2e-42
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            169   6e-42
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             169   6e-42
gi|29366828 synaptotagmin XII [Homo sapiens]                          167   2e-41
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      146   4e-35
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      146   4e-35
gi|24308233 synaptotagmin XIII [Homo sapiens]                         144   1e-34
gi|31881667 synaptotagmin XV isoform b [Homo sapiens]                 144   2e-34
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap...   126   3e-29
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]            124   2e-28
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]            124   2e-28

>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  854 bits (2207), Expect = 0.0
 Identities = 419/419 (100%), Positives = 419/419 (100%)

Query: 1   MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL 60
           MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL
Sbjct: 1   MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL 60

Query: 61  PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA 120
           PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA
Sbjct: 61  PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA 120

Query: 121 ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK 180
           ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK
Sbjct: 121 ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK 180

Query: 181 VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE 240
           VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE
Sbjct: 181 VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE 240

Query: 241 VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM 300
           VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM
Sbjct: 241 VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM 300

Query: 301 DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL 360
           DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL
Sbjct: 301 DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL 360

Query: 361 DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
           DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
Sbjct: 361 DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  854 bits (2207), Expect = 0.0
 Identities = 419/419 (100%), Positives = 419/419 (100%)

Query: 1   MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL 60
           MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL
Sbjct: 1   MRNIFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPL 60

Query: 61  PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA 120
           PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA
Sbjct: 61  PPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKGGQDDDDA 120

Query: 121 ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK 180
           ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK
Sbjct: 121 ETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVK 180

Query: 181 VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE 240
           VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE
Sbjct: 181 VFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGE 240

Query: 241 VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM 300
           VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM
Sbjct: 241 VKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKM 300

Query: 301 DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL 360
           DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL
Sbjct: 301 DVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVL 360

Query: 361 DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
           DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK
Sbjct: 361 DYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  649 bits (1674), Expect = 0.0
 Identities = 324/424 (76%), Positives = 354/424 (83%), Gaps = 11/424 (2%)

Query: 4   IFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPW 63
           + + + E + AP  TT    +    N+TE    GE +ED F+KLKEK  NE++KIPLPPW
Sbjct: 2   VSESHHEALAAPPVTTVATVLP--SNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPW 59

Query: 64  ALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG--------GQ 115
           ALIAIA+VA LL+LTCCFCICKKC  KKK  KK K KG KNA+NMKD+K           
Sbjct: 60  ALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 119

Query: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175
            DDDAETGLT+GE E EE KE E LGKLQ+SLDYDFQ NQL VG++QAAELPALDMGGTS
Sbjct: 120 KDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTS 178

Query: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235
           DPYVKVFLLPDKKKK+ETKVHRKTLNP FNE FTFKVPY ELGGKTLVMA+YDFDRFSKH
Sbjct: 179 DPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKH 238

Query: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295
           DIIGE KVPMNTVD G   EEWRDLQ  EKEE EKLGDIC SLRYVPTAGKLTV ILEAK
Sbjct: 239 DIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298

Query: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355
           NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT+KK TLNPY+NESFSFE+PFEQIQKVQV
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358

Query: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
           VVTVLDYDK+GKN+AIGK+FVG N+TG ELRHWSDMLANPRRPIAQWH+L+ EEEVDA+L
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAML 418

Query: 416 GKNK 419
              K
Sbjct: 419 AVKK 422


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  649 bits (1674), Expect = 0.0
 Identities = 324/424 (76%), Positives = 354/424 (83%), Gaps = 11/424 (2%)

Query: 4   IFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPW 63
           + + + E + AP  TT    +    N+TE    GE +ED F+KLKEK  NE++KIPLPPW
Sbjct: 2   VSESHHEALAAPPVTTVATVLP--SNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPW 59

Query: 64  ALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG--------GQ 115
           ALIAIA+VA LL+LTCCFCICKKC  KKK  KK K KG KNA+NMKD+K           
Sbjct: 60  ALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 119

Query: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175
            DDDAETGLT+GE E EE KE E LGKLQ+SLDYDFQ NQL VG++QAAELPALDMGGTS
Sbjct: 120 KDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTS 178

Query: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235
           DPYVKVFLLPDKKKK+ETKVHRKTLNP FNE FTFKVPY ELGGKTLVMA+YDFDRFSKH
Sbjct: 179 DPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKH 238

Query: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295
           DIIGE KVPMNTVD G   EEWRDLQ  EKEE EKLGDIC SLRYVPTAGKLTV ILEAK
Sbjct: 239 DIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298

Query: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355
           NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT+KK TLNPY+NESFSFE+PFEQIQKVQV
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358

Query: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
           VVTVLDYDK+GKN+AIGK+FVG N+TG ELRHWSDMLANPRRPIAQWH+L+ EEEVDA+L
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAML 418

Query: 416 GKNK 419
              K
Sbjct: 419 AVKK 422


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  649 bits (1674), Expect = 0.0
 Identities = 324/424 (76%), Positives = 354/424 (83%), Gaps = 11/424 (2%)

Query: 4   IFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPW 63
           + + + E + AP  TT    +    N+TE    GE +ED F+KLKEK  NE++KIPLPPW
Sbjct: 2   VSESHHEALAAPPVTTVATVLP--SNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPW 59

Query: 64  ALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG--------GQ 115
           ALIAIA+VA LL+LTCCFCICKKC  KKK  KK K KG KNA+NMKD+K           
Sbjct: 60  ALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 119

Query: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175
            DDDAETGLT+GE E EE KE E LGKLQ+SLDYDFQ NQL VG++QAAELPALDMGGTS
Sbjct: 120 KDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTS 178

Query: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235
           DPYVKVFLLPDKKKK+ETKVHRKTLNP FNE FTFKVPY ELGGKTLVMA+YDFDRFSKH
Sbjct: 179 DPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKH 238

Query: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295
           DIIGE KVPMNTVD G   EEWRDLQ  EKEE EKLGDIC SLRYVPTAGKLTV ILEAK
Sbjct: 239 DIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298

Query: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355
           NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT+KK TLNPY+NESFSFE+PFEQIQKVQV
Sbjct: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358

Query: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
           VVTVLDYDK+GKN+AIGK+FVG N+TG ELRHWSDMLANPRRPIAQWH+L+ EEEVDA+L
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAML 418

Query: 416 GKNK 419
              K
Sbjct: 419 AVKK 422


>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score =  481 bits (1237), Expect = e-136
 Identities = 228/366 (62%), Positives = 293/366 (80%), Gaps = 6/366 (1%)

Query: 53  NEINKIPLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMK 112
           + I+  P+PPWAL  I +V+GLL+ +CCFC+ +K C +++  KK + +   +   +K + 
Sbjct: 20  SRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSC-RRRTGKKSQAQAQVHLQEVKGL- 77

Query: 113 GGQDDDDAETGLTEGE----GEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPA 168
           G    D  +  + E E    G G++  +   LG+LQ+SLDYDFQ+ QL VG+LQA  L A
Sbjct: 78  GQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAA 137

Query: 169 LDMGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYD 228
           LD+GG+SDPYV+V+LLPDK+++YETKVHR+TLNP F ETF FKVPY ELGG+ LVMA+YD
Sbjct: 138 LDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYD 197

Query: 229 FDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLT 288
           FDRFS++D IGEV+VPM++VDLG+P++ WR+LQ   +EE EKLGDIC SLRYVPTAGKLT
Sbjct: 198 FDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLT 257

Query: 289 VCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFE 348
           V +LEAKNLKKMDVGGLSDPYVK+HL+Q GK+++KKKTT+KK TLNPY+NE+FSFE+P +
Sbjct: 258 VIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCD 317

Query: 349 QIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPE 408
           Q+QKVQV +TVLDYDKLGKNEAIG++ VG+ A G  LRHW+DMLANPRRPIAQWHSL+P 
Sbjct: 318 QVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPP 377

Query: 409 EEVDAL 414
           + V  L
Sbjct: 378 DRVRLL 383


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  295 bits (756), Expect = 4e-80
 Identities = 141/280 (50%), Positives = 201/280 (71%), Gaps = 3/280 (1%)

Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
           +GE  + +  ++ GK+ FSL YD++   L V +L+A +LPA D  G+SDPYVK++LLPD+
Sbjct: 133 DGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDR 192

Query: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--M 245
           K K +T+VHRKTLNP F+E F F VPY+EL  + L ++++DFDRFS+HD+IGEV +    
Sbjct: 193 KCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLF 252

Query: 246 NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
              DL +    W+D+Q    E  + LG+I  SL Y+PTAG+LT+ +++ +NLK MD+ G 
Sbjct: 253 EASDLSRETSIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGY 311

Query: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
           SDPYVK+ L+ +G+RLKKKKTT+KK TLNP +NE+  F+IP E + +V ++++V+DYD++
Sbjct: 312 SDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRV 371

Query: 366 GKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
           G NE IG   VG  A G    HW++MLA PR+PIA WHSL
Sbjct: 372 GHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411


>gi|94536846 synaptotagmin VIII [Homo sapiens]
          Length = 401

 Score =  295 bits (754), Expect = 7e-80
 Identities = 157/360 (43%), Positives = 229/360 (63%), Gaps = 21/360 (5%)

Query: 59  PLPPWALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGK---GMKNAMNMKDMKGGQ 115
           P P WALIA A+ AG+LL++C   +C  CCC ++  KK + K   G+ +A         Q
Sbjct: 45  PWPRWALIAGALAAGVLLVSCL--LCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQ 102

Query: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175
            D D   GL    G+ ++       G+LQ SL++DF + ++ VG+ QAA+L     GGT 
Sbjct: 103 PDVD---GLESSPGDAQQ------WGRLQLSLEFDFGSQEIRVGLRQAADLRP---GGTV 150

Query: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235
           DPY +V +      ++ETKVHR TL P F+ET  F +P  EL G TL + +++F RFS H
Sbjct: 151 DPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGH 210

Query: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295
           + +GE+++P+ TVDL   +E W  L      +PE++G++C SLRYVP++G+LTV +LEA+
Sbjct: 211 EPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEAR 270

Query: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355
            L+     GL++PYVK+ LM N ++ KK+KT  KK T  PYFNE+F+F +PF Q+Q V +
Sbjct: 271 GLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDL 326

Query: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
           V+ V D     + E +GK+ +G+ A+G  L+HW+DMLA+ RRPIAQ H L+P  EVD +L
Sbjct: 327 VLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRML 386


>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  294 bits (752), Expect = 1e-79
 Identities = 141/280 (50%), Positives = 200/280 (71%), Gaps = 2/280 (0%)

Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
           E E  E    ENLG++QFS+ Y+FQ + LTV +++A ELPA D  GTSDP+VK++LLPDK
Sbjct: 124 EDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDK 183

Query: 188 KKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246
           K K ETKV RK LNP +NETF F+  PY+++  + L + + D+DRFS++D IGEV +P+N
Sbjct: 184 KHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLN 243

Query: 247 TVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLS 306
            VDL Q    W+DL+        + G++  SL Y P+A  + V I++A+NLK MD+GG S
Sbjct: 244 KVDLTQMQTFWKDLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTS 302

Query: 307 DPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLG 366
           DPYVK+ LM   KR++KKKT   K+ LNP FNESF+F+IP E++++  +++TV+D DKL 
Sbjct: 303 DPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLS 362

Query: 367 KNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLK 406
           +N+ IGKI++   +   E++HW DM+A PR+P+AQWH LK
Sbjct: 363 RNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLK 402


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  285 bits (729), Expect = 5e-77
 Identities = 136/280 (48%), Positives = 193/280 (68%), Gaps = 3/280 (1%)

Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
           + EG + ++ +  GKL F+L YD++   L V +++A +LPA D  GTSDPYVK++LLPD+
Sbjct: 220 DSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDR 279

Query: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--M 245
           KKK++T+VHRKTLNP F+ETF F V Y +L  + L  ++YDFDRFS+HD+IGEV +    
Sbjct: 280 KKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLF 339

Query: 246 NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
              DL +    W+D+     E  + LG+I  SL Y+PTAG++T+ +++ +NLK MD+ G 
Sbjct: 340 EVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGS 398

Query: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
           SDPYVK+ LM  G+RLKK+KTT KK TLNP +NE+  F+IP E + +V + + V+DYD++
Sbjct: 399 SDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRV 458

Query: 366 GKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
           G NE IG    G +A G    HW++MLA  R+PI  WH L
Sbjct: 459 GHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPL 498


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  283 bits (723), Expect = 3e-76
 Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 7/297 (2%)

Query: 127 GEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD 186
           G G GE        G++ F+L Y + ++QL V +LQA +LPA D  G SDPYVK++LLPD
Sbjct: 288 GPGSGEAGTGAP-CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD 346

Query: 187 KKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246
           +KKK++TKVHRKTLNP FNETF F VP  EL  + L  ++YDFDRFS+HD+IG+V V  N
Sbjct: 347 RKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDN 405

Query: 247 TVDLG-QPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVG 303
            ++L  QP +   WRD+  G  E+ + LG++  SL Y+PTAG+LTV I++A NLK MD+ 
Sbjct: 406 LLELAEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464

Query: 304 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
           G SDPYVK  L+  G+RLKK+KT++KK TLNP +NE+  F++  E ++ V + + V+DYD
Sbjct: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524

Query: 364 KLGKNEAIGKIFVGSNATGTELR-HWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
            +G NE IG   VG +A     R HW++MLANPR+P+  WH L  E+ V +    +K
Sbjct: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSK 581


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  283 bits (723), Expect = 3e-76
 Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 7/297 (2%)

Query: 127 GEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD 186
           G G GE        G++ F+L Y + ++QL V +LQA +LPA D  G SDPYVK++LLPD
Sbjct: 288 GPGSGEAGTGAP-CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD 346

Query: 187 KKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246
           +KKK++TKVHRKTLNP FNETF F VP  EL  + L  ++YDFDRFS+HD+IG+V V  N
Sbjct: 347 RKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDN 405

Query: 247 TVDLG-QPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVG 303
            ++L  QP +   WRD+  G  E+ + LG++  SL Y+PTAG+LTV I++A NLK MD+ 
Sbjct: 406 LLELAEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464

Query: 304 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
           G SDPYVK  L+  G+RLKK+KT++KK TLNP +NE+  F++  E ++ V + + V+DYD
Sbjct: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524

Query: 364 KLGKNEAIGKIFVGSNATGTELR-HWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
            +G NE IG   VG +A     R HW++MLANPR+P+  WH L  E+ V +    +K
Sbjct: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSK 581


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  283 bits (723), Expect = 3e-76
 Identities = 148/297 (49%), Positives = 203/297 (68%), Gaps = 7/297 (2%)

Query: 127 GEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD 186
           G G GE        G++ F+L Y + ++QL V +LQA +LPA D  G SDPYVK++LLPD
Sbjct: 288 GPGSGEAGTGAP-CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPD 346

Query: 187 KKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMN 246
           +KKK++TKVHRKTLNP FNETF F VP  EL  + L  ++YDFDRFS+HD+IG+V V  N
Sbjct: 347 RKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDN 405

Query: 247 TVDLG-QPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVG 303
            ++L  QP +   WRD+  G  E+ + LG++  SL Y+PTAG+LTV I++A NLK MD+ 
Sbjct: 406 LLELAEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLT 464

Query: 304 GLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYD 363
           G SDPYVK  L+  G+RLKK+KT++KK TLNP +NE+  F++  E ++ V + + V+DYD
Sbjct: 465 GFSDPYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYD 524

Query: 364 KLGKNEAIGKIFVGSNATGTELR-HWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 419
            +G NE IG   VG +A     R HW++MLANPR+P+  WH L  E+ V +    +K
Sbjct: 525 CIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSK 581


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  281 bits (719), Expect = 8e-76
 Identities = 135/267 (50%), Positives = 188/267 (70%), Gaps = 3/267 (1%)

Query: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKTL 200
           GKL F L YD    QL V + +A  LPA D  GTSDPYVK++LLPD+K K++TKVHRKTL
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281

Query: 201 NPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP--MNTVDLGQPIEEWR 258
           NP F+E F F VPY +L  + L  ++YDFDRFS+HD+IG+V V   ++  D  +    W+
Sbjct: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWK 341

Query: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318
           D++    +  + LG++  SL Y+PTAG+LT+ I++A+NLK MD+ G SDPYVK+ LM +G
Sbjct: 342 DIEYVTNDNVD-LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400

Query: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378
           +RLKK+KT+ K+ TLNP +NE+  F++P E I ++ + + V+DYD++G NE IG   VG+
Sbjct: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460

Query: 379 NATGTELRHWSDMLANPRRPIAQWHSL 405
            A      HWS+ML+ PR+PIA WHSL
Sbjct: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 49/124 (39%), Positives = 74/124 (59%), Gaps = 4/124 (3%)

Query: 139 NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD--KKKKYETKVH 196
           +LG+L FSL Y   A +LT+ +++A  L A+D+ G SDPYVKV L+ D  + KK +T   
Sbjct: 352 DLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTK 411

Query: 197 RKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE 256
           R TLNP +NE   F VP + +    L +A+ D+DR   ++IIG  +V      LG+  + 
Sbjct: 412 RNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DH 469

Query: 257 WRDL 260
           W ++
Sbjct: 470 WSEM 473



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 46/141 (32%), Positives = 74/141 (52%), Gaps = 11/141 (7%)

Query: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318
           D   G +   +  G +   L+Y     +L V I +A NL   D  G SDPYVKI+L+ + 
Sbjct: 209 DNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD- 267

Query: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378
            R  K +T V +KTLNP F+E F F +P+  ++  ++  +V D+D+  +++ IG++ V  
Sbjct: 268 -RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVD- 325

Query: 379 NATGTELRHWSDMLANPRRPI 399
                   H+ D+   PR  I
Sbjct: 326 --------HFLDLADFPRECI 338


>gi|216548478 synaptotagmin XI [Homo sapiens]
          Length = 431

 Score =  231 bits (589), Expect = 9e-61
 Identities = 125/303 (41%), Positives = 190/303 (62%), Gaps = 8/303 (2%)

Query: 111 MKGGQDDDDAETGLTEGEGEGEEEKEPEN---LGKLQFSLDYDFQANQLTVGVLQAAELP 167
           M  G++     T LT GE +      PE    LG L FS+DY+F    L V + +A  LP
Sbjct: 126 MDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLP 185

Query: 168 ALD-MGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMA 225
            +D     SDPY+K+ +LPDK+ + +T+V RKTL+P F+ETFTF  +PY +L    L   
Sbjct: 186 VMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFL 245

Query: 226 IYDFDRFSKHDIIGEVKVPMNTVDLGQ-PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTA 284
           +  FDRFS+ D+IGEV VP+  VD     ++  RD+     ++    G++  SL Y P A
Sbjct: 246 VLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVA 305

Query: 285 GKLTVCILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSF 343
            ++TV +L+A++L KMD+ GLS +PYVK+++    KR+ KKKT VKK TLNP FNESF +
Sbjct: 306 QRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIY 365

Query: 344 EIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNA-TGTELRHWSDMLANPRRPIAQW 402
           +IP + +  + +   V+D+D+  KNE +G++ +G+++ T +   HW ++  +PR+P+A+W
Sbjct: 366 DIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKW 425

Query: 403 HSL 405
           HSL
Sbjct: 426 HSL 428


>gi|24308219 synaptotagmin IV [Homo sapiens]
          Length = 425

 Score =  227 bits (579), Expect = 1e-59
 Identities = 127/295 (43%), Positives = 182/295 (61%), Gaps = 4/295 (1%)

Query: 114 GQDDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALD-MG 172
           G+ +  +   L        EEK+ E LG L FSL+Y+F+     V + +A  LPA+D   
Sbjct: 129 GEKESVSPESLKSSTSLTSEEKQ-EKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187

Query: 173 GTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDR 231
            TSDPY+K+ +LP+KK K +T+V RKTL+PAF+ETFTF  +PY ++    L   I  FDR
Sbjct: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247

Query: 232 FSKHDIIGEVKVPMNTVDLGQ-PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVC 290
           FS+ DIIGEV +P++ ++L +  +   R++      +    G++  SL Y  T   LTV 
Sbjct: 248 FSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVV 307

Query: 291 ILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQI 350
           +L+A++L K DV GLSDPYVK++L    KR+ KKKT VKK T N  FNE F F+IP E +
Sbjct: 308 VLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGL 367

Query: 351 QKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
           + + V   VLD ++  +NE IG++ +G+ A GT   HW ++   PRR IA+WH L
Sbjct: 368 EDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422


>gi|40068038 B/K protein [Homo sapiens]
          Length = 474

 Score =  222 bits (566), Expect = 4e-58
 Identities = 119/289 (41%), Positives = 177/289 (61%), Gaps = 9/289 (3%)

Query: 132 EEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPA-LDMGGT------SDPYVKVFLL 184
           EE      LG L FS  YD   N LTV V++A +LP  +   G+      S+PYVK+ LL
Sbjct: 177 EEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLL 236

Query: 185 PDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP 244
           PD+K   +T V RKT  P F E +TF++P+ E   +TL++ + DFD+FS+H +IG+V VP
Sbjct: 237 PDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVP 296

Query: 245 MNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGG 304
           +  VDL +    W+ L    + E E LG++  SL Y+P+AG+L V ++ AK L + DV  
Sbjct: 297 LCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQ 355

Query: 305 LSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDK 364
            SDP+VKI L+   K +K KKT+  + T++P++NESFSF++P E+++   +V TV  ++ 
Sbjct: 356 GSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNM 415

Query: 365 LGKNEAIGKIFVGSNATG-TELRHWSDMLANPRRPIAQWHSLKPEEEVD 412
              N+ IG+I +G  ++G +E  HW  ML   R  + QWHSL+   E D
Sbjct: 416 KSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAECD 464


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  186 bits (473), Expect = 3e-47
 Identities = 113/292 (38%), Positives = 159/292 (54%), Gaps = 9/292 (3%)

Query: 126 EGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP 185
           E + +G E  +   LG L FSL YD + N L   + +A  L  +D  G +DPYVK+ LLP
Sbjct: 113 EPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLP 172

Query: 186 --DKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVK 242
              K  K  TK  R TLNP +NET T+  +  +++  KTL +++ D D+F  ++ IGE +
Sbjct: 173 GASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETR 232

Query: 243 VPM------NTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKN 296
           VP+      +T      +E+   +   E +  E+ G I  SL+Y      L V I+   +
Sbjct: 233 VPLKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAH 292

Query: 297 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVV 356
           L  MD  G SDPYVK +L  +  +  K KT VKKKTLNP FNE F +EI    + K  + 
Sbjct: 293 LAAMDANGYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLE 352

Query: 357 VTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPE 408
           VTV DYD    N+ IG + +G +A G  L+HW D L N  + I +WH+L  E
Sbjct: 353 VTVWDYDIGKSNDFIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSE 404



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 45/123 (36%), Positives = 67/123 (54%), Gaps = 1/123 (0%)

Query: 252 QPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVK 311
           +P E+  D  G E ++   LG +  SL Y      L   I +AK LK MD  GL+DPYVK
Sbjct: 108 KPPEDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVK 167

Query: 312 IHLMQNGKRLKKKKTTVKKKTLNPYFNESFS-FEIPFEQIQKVQVVVTVLDYDKLGKNEA 370
           +HL+    +  K +T   + TLNP +NE+ + + I  E + +  + ++V D DK   NE 
Sbjct: 168 LHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEF 227

Query: 371 IGK 373
           IG+
Sbjct: 228 IGE 230


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score =  174 bits (442), Expect = 1e-43
 Identities = 95/282 (33%), Positives = 159/282 (56%), Gaps = 6/282 (2%)

Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
           E + E +     LG+L FS++Y+ +A +L VG+++A  L A     T  P VK++LLPD+
Sbjct: 136 EDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSPLVKLYLLPDE 193

Query: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
           ++  ++K  RKT NP F+E F F+V  + +  + L  ++Y  DR  KH ++G+V  P+  
Sbjct: 194 RRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN 253

Query: 248 VDLGQPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
             L        WRDL+    E P + GD+   L Y     +LTV +L AK L+  +  G+
Sbjct: 254 ETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGI 313

Query: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
              +VK+ LM + K +K KKT+    ++NP +NE+FSF+    ++    + +TV+   + 
Sbjct: 314 VSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEG 373

Query: 366 GKNEAIGKIFVG--SNATGTELRHWSDMLANPRRPIAQWHSL 405
            K++ +G++ VG      G EL HW +ML+ P+  + +WH+L
Sbjct: 374 DKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 45/148 (30%), Positives = 69/148 (46%), Gaps = 2/148 (1%)

Query: 130 EGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKK- 188
           E E  + P   G LQF L Y+   ++LTV VL+A  L   +  G    +VKV L+   K 
Sbjct: 269 EAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNHNKF 328

Query: 189 -KKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
            K  +T     ++NP +NETF+FK    EL   +L + +       K   +G V V    
Sbjct: 329 VKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYM 388

Query: 248 VDLGQPIEEWRDLQGGEKEEPEKLGDIC 275
              G+ +E W ++    KE  ++   +C
Sbjct: 389 YTRGRELEHWDEMLSKPKELVKRWHALC 416


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score =  170 bits (431), Expect = 2e-42
 Identities = 113/312 (36%), Positives = 154/312 (49%), Gaps = 31/312 (9%)

Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPD- 186
           E +  +  +   LG L+F L YD  +  L   +L+A  L  +D  G +DPYVK+ LLP  
Sbjct: 78  EVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGA 137

Query: 187 -KKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVP 244
            K  K +TK  R TLNP +NE  T+  +   ++  K L +A+ D D+ S ++ IGE++VP
Sbjct: 138 CKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVP 197

Query: 245 M----------------NTVDLGQPIEEWRDLQG-----GEKEEP-------EKLGDICT 276
           +                  V L  P      L+G      E E+        E+ G I  
Sbjct: 198 LRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILL 257

Query: 277 SLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPY 336
           SL Y      L V IL   +L  MDV G SDPYVK +L  +  +  K KT VKKKTLNP 
Sbjct: 258 SLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPE 317

Query: 337 FNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPR 396
           FNE F +EI    +    + VTV DYD    N+ IG + +G  A G   +HWSD L  P 
Sbjct: 318 FNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPD 377

Query: 397 RPIAQWHSLKPE 408
             + +WH+L  E
Sbjct: 378 AALERWHTLTSE 389



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 45/123 (36%), Positives = 66/123 (53%), Gaps = 1/123 (0%)

Query: 255 EEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHL 314
           E+  ++   + ++   LG +   L Y   +  L   IL AK LK MD  GL+DPYVK+HL
Sbjct: 74  EDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHL 133

Query: 315 MQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLDYDKLGKNEAIGK 373
           +    +  K KT  ++ TLNP +NE  ++  I  + I    + + V D DKL  NE IG+
Sbjct: 134 LPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGE 193

Query: 374 IFV 376
           I V
Sbjct: 194 IRV 196


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  169 bits (427), Expect = 6e-42
 Identities = 107/315 (33%), Positives = 160/315 (50%), Gaps = 27/315 (8%)

Query: 126 EGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP 185
           E E    +  E   LG L+FSL YD   + L   +++A  L  +D  G +DPYVK+ LLP
Sbjct: 379 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP 438

Query: 186 --DKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVK 242
              K  K  TK  R T NP +NET  +  +  +++  KTL +++ D D+F  ++ IGE +
Sbjct: 439 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR 498

Query: 243 VPMNTVDLGQ------------PIEEW------RDLQGGEKEEPEKLGDI------CTSL 278
             +  +   Q            P++        R +   E+E+ E++GDI        SL
Sbjct: 499 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL 558

Query: 279 RYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFN 338
            Y    G L V I+   +L  MD  G SDP+VK+ L  +  +  K KT +KKKTLNP FN
Sbjct: 559 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN 618

Query: 339 ESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRP 398
           E F ++I    + K  + ++V DYD    N+ IG   +G +A G  L+HW + L N  + 
Sbjct: 619 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK 678

Query: 399 IAQWHSLKPEEEVDA 413
           I +WH L+ E  V +
Sbjct: 679 IERWHQLQNENHVSS 693



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 45/122 (36%), Positives = 66/122 (54%), Gaps = 1/122 (0%)

Query: 253 PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKI 312
           P EE  +    + +E   LG +  SL Y      L   I++AK LK MD  GL+DPYVK+
Sbjct: 375 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 434

Query: 313 HLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLDYDKLGKNEAI 371
           HL+    +  K +T   + T NP +NE+  +  I  E +Q+  + ++V D DK G NE I
Sbjct: 435 HLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFI 494

Query: 372 GK 373
           G+
Sbjct: 495 GE 496


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  169 bits (427), Expect = 6e-42
 Identities = 107/315 (33%), Positives = 160/315 (50%), Gaps = 27/315 (8%)

Query: 126 EGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP 185
           E E    +  E   LG L+FSL YD   + L   +++A  L  +D  G +DPYVK+ LLP
Sbjct: 375 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP 434

Query: 186 --DKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVK 242
              K  K  TK  R T NP +NET  +  +  +++  KTL +++ D D+F  ++ IGE +
Sbjct: 435 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR 494

Query: 243 VPMNTVDLGQ------------PIEEW------RDLQGGEKEEPEKLGDI------CTSL 278
             +  +   Q            P++        R +   E+E+ E++GDI        SL
Sbjct: 495 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL 554

Query: 279 RYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFN 338
            Y    G L V I+   +L  MD  G SDP+VK+ L  +  +  K KT +KKKTLNP FN
Sbjct: 555 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN 614

Query: 339 ESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRP 398
           E F ++I    + K  + ++V DYD    N+ IG   +G +A G  L+HW + L N  + 
Sbjct: 615 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK 674

Query: 399 IAQWHSLKPEEEVDA 413
           I +WH L+ E  V +
Sbjct: 675 IERWHQLQNENHVSS 689



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 45/122 (36%), Positives = 66/122 (54%), Gaps = 1/122 (0%)

Query: 253 PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKI 312
           P EE  +    + +E   LG +  SL Y      L   I++AK LK MD  GL+DPYVK+
Sbjct: 371 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 430

Query: 313 HLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLDYDKLGKNEAI 371
           HL+    +  K +T   + T NP +NE+  +  I  E +Q+  + ++V D DK G NE I
Sbjct: 431 HLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFI 490

Query: 372 GK 373
           G+
Sbjct: 491 GE 492


>gi|29366828 synaptotagmin XII [Homo sapiens]
          Length = 421

 Score =  167 bits (422), Expect = 2e-41
 Identities = 87/268 (32%), Positives = 158/268 (58%), Gaps = 2/268 (0%)

Query: 140 LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKT 199
           LG+++ S++YD  ++ L V V+Q  +L   +       +++V LLPD++    +++ R  
Sbjct: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212

Query: 200 LNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLG-QPIEEWR 258
            +  F+E F+  +    L  K+L  +++  D   ++   G V++ ++ +DL  QP   W 
Sbjct: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272

Query: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318
            LQ   K   + +G+I  SL Y+PTA +LTV +++AKNL   +    +DP+VK++L+Q+G
Sbjct: 273 YLQDQNKAA-DAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331

Query: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378
           +++ KKKT VK+   NP FNE+  F +P   +Q + + VTV +    G+ + +G + +G 
Sbjct: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391

Query: 379 NATGTELRHWSDMLANPRRPIAQWHSLK 406
           +A+G    HW+ MLA  RRP++ WH+++
Sbjct: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 2/122 (1%)

Query: 132 EEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKK-- 189
           ++ K  + +G++  SL Y   A +LTV V++A  L   +   T+DP+VKV+LL D +K  
Sbjct: 276 DQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMS 335

Query: 190 KYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVD 249
           K +T V R   NP FNE   F VP   L   +L + + +     + D +G V +  +   
Sbjct: 336 KKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASG 395

Query: 250 LG 251
           +G
Sbjct: 396 MG 397


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  146 bits (368), Expect = 4e-35
 Identities = 89/277 (32%), Positives = 147/277 (53%), Gaps = 27/277 (9%)

Query: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197
           G++ FSL Y+ Q   L V V +  +L   D     S+PYVK +LLPDK +  K +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257
            T+NP ++ET  +++P   L  +TL  +++   RF ++  +GE ++ M++  L + ++  
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477

Query: 258 RDLQGGEKEE-----PEKLGDICTSLRYVPTA----------------GKLTVCILEAKN 296
             L G    E     P   G++  SL+Y+P +                G+L V I EAKN
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 297 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQV 355
           L     GG SD +VK +L+    +  K+KT V KKTLNP++N +F +  +  E +Q + +
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 356 VVTVLDYDKLGKNEAIG--KIFVGSNATGTELRHWSD 390
            +TV D + L  N+ +G  ++ VG+  +  E+  W D
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMD 634



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 3/116 (2%)

Query: 152 QANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP--DKKKKYETKVHRKTLNPAFNETFT 209
           +  +L V + +A  L A   GGTSD +VK +LLP  +K  K +T V +KTLNP +N TF 
Sbjct: 524 EGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFV 583

Query: 210 FK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 264
           +  V  ++L    L + ++D +  + +D +G V++ + T      + +W D  G E
Sbjct: 584 YNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEE 639


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  146 bits (368), Expect = 4e-35
 Identities = 89/277 (32%), Positives = 147/277 (53%), Gaps = 27/277 (9%)

Query: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197
           G++ FSL Y+ Q   L V V +  +L   D     S+PYVK +LLPDK +  K +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257
            T+NP ++ET  +++P   L  +TL  +++   RF ++  +GE ++ M++  L + ++  
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477

Query: 258 RDLQGGEKEE-----PEKLGDICTSLRYVPTA----------------GKLTVCILEAKN 296
             L G    E     P   G++  SL+Y+P +                G+L V I EAKN
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 297 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQV 355
           L     GG SD +VK +L+    +  K+KT V KKTLNP++N +F +  +  E +Q + +
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 356 VVTVLDYDKLGKNEAIG--KIFVGSNATGTELRHWSD 390
            +TV D + L  N+ +G  ++ VG+  +  E+  W D
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMD 634



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 3/116 (2%)

Query: 152 QANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP--DKKKKYETKVHRKTLNPAFNETFT 209
           +  +L V + +A  L A   GGTSD +VK +LLP  +K  K +T V +KTLNP +N TF 
Sbjct: 524 EGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFV 583

Query: 210 FK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 264
           +  V  ++L    L + ++D +  + +D +G V++ + T      + +W D  G E
Sbjct: 584 YNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEE 639


>gi|24308233 synaptotagmin XIII [Homo sapiens]
          Length = 426

 Score =  144 bits (364), Expect = 1e-34
 Identities = 86/267 (32%), Positives = 140/267 (52%), Gaps = 6/267 (2%)

Query: 142 KLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKK-KYETKVHRKTL 200
           KL + LDYD Q  +L V  L+A      +  G  D YV+  +       + +T + ++ L
Sbjct: 161 KLHYCLDYDCQKAELFVTRLEAV---TSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQL 217

Query: 201 NPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDL 260
           +  + E     +  +EL   TL + +   DRFS+H + GE+++ ++   +     +W +L
Sbjct: 218 HTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGEL 277

Query: 261 QGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL--SDPYVKIHLMQNG 318
           +   KE     G++  S+ Y+P A +L V +++AKNL       L   D  VK+ L    
Sbjct: 278 KTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQA 337

Query: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378
           ++LKKK+T   K  +NP +NE   FE+P + +Q   V + VL  D  G++ A+G   +G 
Sbjct: 338 RKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGL 397

Query: 379 NATGTELRHWSDMLANPRRPIAQWHSL 405
           + +G+E  HW +ML NPRR IA WH L
Sbjct: 398 HTSGSERSHWEEMLKNPRRQIAMWHQL 424


>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
          Length = 390

 Score =  144 bits (362), Expect = 2e-34
 Identities = 82/251 (32%), Positives = 138/251 (54%), Gaps = 4/251 (1%)

Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
           E + E +     LG+L FS++Y+ +A +L VG+++A  L A     T  P VK++LLPD+
Sbjct: 136 EDKSETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSPLVKLYLLPDE 193

Query: 188 KKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNT 247
           ++  ++K  RKT NP F+E F F+V  + +  + L  ++Y  DR  KH ++G+V  P+  
Sbjct: 194 RRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN 253

Query: 248 VDLGQPIEE--WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGL 305
             L        WRDL+    E P + GD+   L Y     +LTV +L AK L+  +  G+
Sbjct: 254 ETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGI 313

Query: 306 SDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKL 365
              +VK+ LM + K +K KKT+    ++NP +NE+FSF+    ++    + +TV+   + 
Sbjct: 314 VSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEG 373

Query: 366 GKNEAIGKIFV 376
            K     ++F+
Sbjct: 374 DKQATTVELFL 384


>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
           sapiens]
          Length = 431

 Score =  126 bits (317), Expect = 3e-29
 Identities = 96/297 (32%), Positives = 146/297 (49%), Gaps = 21/297 (7%)

Query: 128 EGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDK 187
           E EG+ + +   LG L+F+L ++   + L     +A  L  L   G++D YVK  LLP  
Sbjct: 128 EPEGDSD-DSTALGTLEFTLLFEADNSALHCTAHRAKGLKPL-ASGSADAYVKANLLPGA 185

Query: 188 KKKYETKVH--RKTLNPAFNETFTF----------KVPYQELGGKTLVMAIYDF-DRFSK 234
            K  + + H  R T  P + ET T+          K    +LGG   V        R  +
Sbjct: 186 SKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQRQWQ 245

Query: 235 HDIIGEVKVPMNTVDLGQPIE-----EWRDLQGGEKEEP-EKLGDICTSLRYVPTAGKLT 288
              +GE++VP+  +   +        E R L+  E E   E+ G +  SL Y    G L 
Sbjct: 246 APSLGELRVPLRKLVPNRARSFDICLEKRRLEEVETEVAWEECGHVLLSLCYSSQQGGLL 305

Query: 289 VCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFE 348
           V +L   +L  MD  G SDP+V++ L  N  +  K KT+V +KTLNP FNE F +  P E
Sbjct: 306 VGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPRE 365

Query: 349 QIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSL 405
           ++ +  ++V+V DYD    ++ IG + +GS+A+G  LRHW + L +    +  WH L
Sbjct: 366 ELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHWLECLGHSDHRLKLWHPL 422


>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
          Length = 730

 Score =  124 bits (310), Expect = 2e-28
 Identities = 89/308 (28%), Positives = 146/308 (47%), Gaps = 51/308 (16%)

Query: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALD-MGGTSDPYVKVFLLPDKKK--KYETKVHR 197
           G++   + Y ++   L + V     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 408 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 467

Query: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257
            T NP FNET  + + + +L  +TL ++++ +DRF ++  +GEV++P ++ +   P +EW
Sbjct: 468 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 526

Query: 258 RDLQGGEKEEP----EKLGDICTSLRYVP-----------------------------TA 284
             LQ   +  P    +  G++   LRY+P                             + 
Sbjct: 527 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 586

Query: 285 GKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE 344
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT V KK++NP +N +F F 
Sbjct: 587 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 646

Query: 345 -IPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS-------------NATGTELRHWSD 390
            I  + I+ V + +T+ D +    N  +G + + S             ++ G E R W  
Sbjct: 647 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 706

Query: 391 MLANPRRP 398
           M  NP  P
Sbjct: 707 MANNPGTP 714


>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
          Length = 752

 Score =  124 bits (310), Expect = 2e-28
 Identities = 89/308 (28%), Positives = 146/308 (47%), Gaps = 51/308 (16%)

Query: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALD-MGGTSDPYVKVFLLPDKKK--KYETKVHR 197
           G++   + Y ++   L + V     L   D     +D YVK +LLPDK +  K +TK+  
Sbjct: 430 GEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRT 489

Query: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257
            T NP FNET  + + + +L  +TL ++++ +DRF ++  +GEV++P ++ +   P +EW
Sbjct: 490 GT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEW 548

Query: 258 RDLQGGEKEEP----EKLGDICTSLRYVP-----------------------------TA 284
             LQ   +  P    +  G++   LRY+P                             + 
Sbjct: 549 FVLQPKVEFAPDIGLQYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISG 608

Query: 285 GKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE 344
           G L V I EAKNL  +  GG SD +VK +L+ +  +  K KT V KK++NP +N +F F 
Sbjct: 609 GILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFS 668

Query: 345 -IPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS-------------NATGTELRHWSD 390
            I  + I+ V + +T+ D +    N  +G + + S             ++ G E R W  
Sbjct: 669 GIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQK 728

Query: 391 MLANPRRP 398
           M  NP  P
Sbjct: 729 MANNPGTP 736


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.135    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,944,086
Number of Sequences: 37866
Number of extensions: 804359
Number of successful extensions: 4109
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 2997
Number of HSP's gapped (non-prelim): 660
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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