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Search of human proteins with 209447073
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|209447073 synaptotagmin I [Homo sapiens]
(422 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209447073 synaptotagmin I [Homo sapiens] 852 0.0
gi|5032139 synaptotagmin I [Homo sapiens] 852 0.0
gi|209447070 synaptotagmin I [Homo sapiens] 852 0.0
gi|211059429 synaptotagmin II [Homo sapiens] 649 0.0
gi|31543670 synaptotagmin II [Homo sapiens] 649 0.0
gi|92859638 synaptotagmin V [Homo sapiens] 474 e-134
gi|45504376 synaptotagmin VI [Homo sapiens] 298 8e-81
gi|38570146 synaptotagmin VII [Homo sapiens] 290 2e-78
gi|39752671 synaptotagmin X [Homo sapiens] 288 5e-78
gi|28376627 synaptotagmin IX [Homo sapiens] 286 3e-77
gi|94536846 synaptotagmin VIII [Homo sapiens] 283 2e-76
gi|238550198 synaptotagmin III [Homo sapiens] 281 6e-76
gi|238550196 synaptotagmin III [Homo sapiens] 281 6e-76
gi|14150054 synaptotagmin III [Homo sapiens] 281 6e-76
gi|216548478 synaptotagmin XI [Homo sapiens] 230 2e-60
gi|40068038 B/K protein [Homo sapiens] 225 5e-59
gi|24308219 synaptotagmin IV [Homo sapiens] 222 4e-58
gi|6005997 double C2-like domains, beta [Homo sapiens] 184 2e-46
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 177 2e-44
gi|47078261 double C2-like domains, alpha [Homo sapiens] 168 1e-41
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 167 1e-41
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 167 1e-41
gi|29366828 synaptotagmin XII [Homo sapiens] 160 3e-39
gi|24308233 synaptotagmin XIII [Homo sapiens] 150 3e-36
gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 147 1e-35
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 135 9e-32
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 135 9e-32
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 129 7e-30
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] 122 6e-28
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] 122 6e-28
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 852 bits (2201), Expect = 0.0
Identities = 422/422 (100%), Positives = 422/422 (100%)
Query: 1 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60
MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
Sbjct: 1 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60
Query: 61 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120
LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
Sbjct: 61 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120
Query: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
Query: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300
IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
Sbjct: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300
Query: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360
KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
Sbjct: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360
Query: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420
TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
Sbjct: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420
Query: 421 KK 422
KK
Sbjct: 421 KK 422
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 852 bits (2201), Expect = 0.0
Identities = 422/422 (100%), Positives = 422/422 (100%)
Query: 1 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60
MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
Sbjct: 1 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60
Query: 61 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120
LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
Sbjct: 61 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120
Query: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
Query: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300
IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
Sbjct: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300
Query: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360
KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
Sbjct: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360
Query: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420
TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
Sbjct: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420
Query: 421 KK 422
KK
Sbjct: 421 KK 422
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 852 bits (2201), Expect = 0.0
Identities = 422/422 (100%), Positives = 422/422 (100%)
Query: 1 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60
MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
Sbjct: 1 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60
Query: 61 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120
LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
Sbjct: 61 LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120
Query: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
Query: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
Query: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300
IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
Sbjct: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300
Query: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360
KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
Sbjct: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360
Query: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420
TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
Sbjct: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420
Query: 421 KK 422
KK
Sbjct: 421 KK 422
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 649 bits (1674), Expect = 0.0
Identities = 324/424 (76%), Positives = 354/424 (83%), Gaps = 11/424 (2%)
Query: 2 VSESHHEALAAPPVTTVATVLP--SNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPW 59
+ + + E + AP TT + N+TE GE +ED F+KLKEK NE++KIPLPPW
Sbjct: 4 IFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPW 63
Query: 60 ALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 119
ALIAIA+VA LL+LTCCFCICKKC KKK KK K KG KNA+NMKD+K
Sbjct: 64 ALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG--------GQ 115
Query: 120 KDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTS 178
DDDAETGLT+GE E EE KE E LGKLQ+SLDYDFQ NQL VG++QAAELPALDMGGTS
Sbjct: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175
Query: 179 DPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKH 238
DPYVKVFLLPDKKKK+ETKVHRKTLNP FNE FTFKVPY ELGGKTLVMA+YDFDRFSKH
Sbjct: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235
Query: 239 DIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
DIIGE KVPMNTVD G EEWRDLQ EKEE EKLGDIC SLRYVPTAGKLTV ILEAK
Sbjct: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295
Query: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT+KK TLNPY+NESFSFE+PFEQIQKVQV
Sbjct: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355
Query: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAML 418
VVTVLDYDK+GKN+AIGK+FVG N+TG ELRHWSDMLANPRRPIAQWH+L+ EEEVDA+L
Sbjct: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
Query: 419 AVKK 422
K
Sbjct: 416 GKNK 419
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 649 bits (1674), Expect = 0.0
Identities = 324/424 (76%), Positives = 354/424 (83%), Gaps = 11/424 (2%)
Query: 2 VSESHHEALAAPPVTTVATVLP--SNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPW 59
+ + + E + AP TT + N+TE GE +ED F+KLKEK NE++KIPLPPW
Sbjct: 4 IFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPW 63
Query: 60 ALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 119
ALIAIA+VA LL+LTCCFCICKKC KKK KK K KG KNA+NMKD+K
Sbjct: 64 ALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG--------GQ 115
Query: 120 KDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTS 178
DDDAETGLT+GE E EE KE E LGKLQ+SLDYDFQ NQL VG++QAAELPALDMGGTS
Sbjct: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175
Query: 179 DPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKH 238
DPYVKVFLLPDKKKK+ETKVHRKTLNP FNE FTFKVPY ELGGKTLVMA+YDFDRFSKH
Sbjct: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235
Query: 239 DIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
DIIGE KVPMNTVD G EEWRDLQ EKEE EKLGDIC SLRYVPTAGKLTV ILEAK
Sbjct: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295
Query: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT+KK TLNPY+NESFSFE+PFEQIQKVQV
Sbjct: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355
Query: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAML 418
VVTVLDYDK+GKN+AIGK+FVG N+TG ELRHWSDMLANPRRPIAQWH+L+ EEEVDA+L
Sbjct: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415
Query: 419 AVKK 422
K
Sbjct: 416 GKNK 419
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 474 bits (1221), Expect = e-134
Identities = 231/387 (59%), Positives = 299/387 (77%), Gaps = 10/387 (2%)
Query: 28 EPASPGEGKEDAFSKLKEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKKCLFKK 87
EP +PG D + + P+PPWAL I +V+ LL+ +CCFC+ +K
Sbjct: 4 EPPTPGPPSPDT-----PPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSC--- 55
Query: 88 KNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQ 147
++ GK+ + +++++VK LG++ D+ + + G ++ + E LG+LQ
Sbjct: 56 -RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE-LGRLQ 113
Query: 148 YSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVF 207
YSLDYDFQ+ QLLVGI+QA L ALD+GG+SDPYV+V+LLPDK++++ETKVHR+TLNP F
Sbjct: 114 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF 173
Query: 208 NEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAE 267
E F FKVPY ELGG+ LVMAVYDFDRFS++D IGE +VPM++VD G + WR+LQ+A
Sbjct: 174 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP 233
Query: 268 KEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKK 327
+EEQEKLGDICFSLRYVPTAGKLTV++LEAKNLKKMDVGGLSDPYVK+HL+Q GK+++KK
Sbjct: 234 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK 293
Query: 328 KTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAE 387
KTTIKKNTLNPYYNE+FSFEVP +Q+QKVQV +TVLDYDK+GKN+AIG+V VG + GA
Sbjct: 294 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG 353
Query: 388 LRHWSDMLANPRRPIAQWHTLQVEEEV 414
LRHW+DMLANPRRPIAQWH+L+ + V
Sbjct: 354 LRHWADMLANPRRPIAQWHSLRPPDRV 380
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 298 bits (762), Expect = 8e-81
Identities = 142/281 (50%), Positives = 202/281 (71%), Gaps = 4/281 (1%)
Query: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
DGE+ + + + GK+ +SL YD++ L+V I++A +LPA D G+SDPYVK++LLPD
Sbjct: 133 DGEDAKS-EATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPD 191
Query: 190 KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP-- 247
+K K +T+VHRKTLNP F+E F F VPY EL + L ++V+DFDRFS+HD+IGE +
Sbjct: 192 RKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNL 251
Query: 248 MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGG 307
D T W+D+Q A E + LG+I FSL Y+PTAG+LT+ +++ +NLK MD+ G
Sbjct: 252 FEASDLSRETSIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITG 310
Query: 308 LSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDK 367
SDPYVK+ L+ +G+RLKKKKTTIKKNTLNP YNE+ F++P E + +V ++++V+DYD+
Sbjct: 311 YSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDR 370
Query: 368 IGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
+G N+ IG VG + G HW++MLA PR+PIA WH+L
Sbjct: 371 VGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 290 bits (742), Expect = 2e-78
Identities = 155/388 (39%), Positives = 232/388 (59%), Gaps = 42/388 (10%)
Query: 61 LIAIAIVAVLLVLTCCFC-ICKKCLFK--------------------KKNKKKGKEKGGK 99
L+ AI+ V L +T C +C C K + KK K G
Sbjct: 18 LLVSAIITVSLSVTVVLCGLCHWCQRKLGKRYKNSLETVGTPDSGRGRSEKKAIKLPAGG 77
Query: 100 NAINMKDVKDLGKTMKDQALKDDDAETGLTD--------------GEEKEEPKE---EEK 142
A+N V G+T D++ + + + ++D G E++E E E
Sbjct: 78 KAVNTAPVP--GQTPHDESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSREN 135
Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 202
LG++Q+S+ Y+FQ + L V I++A ELPA D GTSDP+VK++LLPDKK K ETKV RK
Sbjct: 136 LGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKN 195
Query: 203 LNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWR 261
LNP +NE F F+ PY ++ + L + V D+DRFS++D IGE +P+N VD + W+
Sbjct: 196 LNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWK 255
Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
DL+ + G++ SL Y P+A + V I++A+NLK MD+GG SDPYVK+ LM
Sbjct: 256 DLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKD 314
Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
KR++KKKT K LNP +NESF+F++P E++++ +++TV+D DK+ +ND IGK+++ +
Sbjct: 315 KRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSW 374
Query: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQ 409
S E++HW DM+A PR+P+AQWH L+
Sbjct: 375 KSGPGEVKHWKDMIARPRQPVAQWHQLK 402
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 288 bits (738), Expect = 5e-78
Identities = 139/282 (49%), Positives = 195/282 (69%), Gaps = 6/282 (2%)
Query: 129 TDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP 188
++G + E+ K GKL ++L YD++N L+V II+A +LPA D GTSDPYVK++LLP
Sbjct: 221 SEGNQNEDVKI---CGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLP 277
Query: 189 DKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP- 247
D+KKKF+T+VHRKTLNP+F+E F F V Y +L + L +VYDFDRFS+HD+IGE +
Sbjct: 278 DRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDN 337
Query: 248 -MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVG 306
D W+D+ A E + LG+I FSL Y+PTAG++T+ +++ +NLK MD+
Sbjct: 338 LFEVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDIT 396
Query: 307 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 366
G SDPYVK+ LM G+RLKK+KTT KKNTLNP YNE+ F++P E + +V + + V+DYD
Sbjct: 397 GSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYD 456
Query: 367 KIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
++G N+ IG G ++ G HW++MLA R+PI WH L
Sbjct: 457 RVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPL 498
Score = 77.0 bits (188), Expect = 3e-14
Identities = 40/118 (33%), Positives = 72/118 (61%), Gaps = 2/118 (1%)
Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
D + + E+ + G + F+L+Y L V I++A +L D G SDPYVK++L+ +
Sbjct: 220 DSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPD- 278
Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFV 379
R KK +T + + TLNP ++E+F F V ++Q+ ++ +V D+D+ ++D IG+V +
Sbjct: 279 -RKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL 335
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 286 bits (731), Expect = 3e-77
Identities = 138/267 (51%), Positives = 190/267 (71%), Gaps = 3/267 (1%)
Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
GKL + L YD QL+V I +A LPA D GTSDPYVK++LLPD+K K +TKVHRKTL
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
Query: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP--MNTVDFGHVTEEWR 261
NPVF+E F F VPY++L + L +VYDFDRFS+HD+IG+ V ++ DF W+
Sbjct: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWK 341
Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
D++ + + LG++ FSL Y+PTAG+LT+ I++A+NLK MD+ G SDPYVK+ LM +G
Sbjct: 342 DIEYVTNDNVD-LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400
Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
+RLKK+KT+ K+NTLNP YNE+ F+VP E I ++ + + V+DYD++G N+ IG VG
Sbjct: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460
Query: 382 NSTGAELRHWSDMLANPRRPIAQWHTL 408
+ HWS+ML+ PR+PIA WH+L
Sbjct: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487
Score = 81.3 bits (199), Expect = 2e-15
Identities = 50/125 (40%), Positives = 70/125 (56%), Gaps = 4/125 (3%)
Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
LG+L +SL Y +L + II+A L A+D+ G SDPYVKV L+ D + KK +T R
Sbjct: 353 LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKR 412
Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
TLNPV+NE F VP + L +AV D+DR ++IIG +V G + W
Sbjct: 413 NTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DHW 470
Query: 261 RDLQS 265
++ S
Sbjct: 471 SEMLS 475
Score = 76.3 bits (186), Expect = 5e-14
Identities = 41/120 (34%), Positives = 67/120 (55%), Gaps = 2/120 (1%)
Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
D + + G + F L+Y +L V I +A NL D G SDPYVKI+L+ +
Sbjct: 209 DNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD- 267
Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
R K +T + + TLNP ++E F F VP+ ++ ++ +V D+D+ ++D IG+V V +
Sbjct: 268 -RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDH 326
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 283 bits (725), Expect = 2e-76
Identities = 155/367 (42%), Positives = 226/367 (61%), Gaps = 22/367 (5%)
Query: 55 PLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTM 114
P P WALIA A+ A +L+++C C C + + K + KE G + G T
Sbjct: 45 PWPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSAR-------GTTT 97
Query: 115 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM 174
D D GL + P + ++ G+LQ SL++DF + ++ VG+ QAA+L
Sbjct: 98 THLVQPDVD---GL-----ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146
Query: 175 GGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDR 234
GGT DPY +V + + ETKVHR TL PVF+E F +P +EL G TL + +++F R
Sbjct: 147 GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKR 206
Query: 235 FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVI 294
FS H+ +GE ++P+ TVD HV E W L + E++G++CFSLRYVP++G+LTVV+
Sbjct: 207 FSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVV 266
Query: 295 LEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354
LEA+ L+ GL++PYVK+ LM N ++ KK+KT KK T PY+NE+F+F VPF Q+Q
Sbjct: 267 LEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQ 322
Query: 355 KVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414
V +V+ V D + + +GKV +G ++G L+HW+DMLA+ RRPIAQ H L+ EV
Sbjct: 323 NVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREV 382
Query: 415 DAMLAVK 421
D MLA++
Sbjct: 383 DRMLALQ 389
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 281 bits (720), Expect = 6e-76
Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)
Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
G++ ++L Y + ++QL+V I+QA +LPA D G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
Query: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260
NPVFNE F F VP +EL + L +VYDFDRFS+HD+IG+ V N ++ + W
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419
Query: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320
RD+ E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK L+
Sbjct: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478
Query: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380
G+RLKK+KT+IKKNTLNP YNE+ F+V E ++ V + + V+DYD IG N+ IG VG
Sbjct: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
Query: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414
++ R HW++MLANPR+P+ WH L E+ V
Sbjct: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573
Score = 79.7 bits (195), Expect = 5e-15
Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)
Query: 29 PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82
PA G D + K+ K+KF ++H+ L P L L +K
Sbjct: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381
Query: 83 CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142
F + + + + ++ +L + D+ L D E G E+
Sbjct: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431
Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
LG+L +SL Y +L V II+A+ L A+D+ G SDPYVK L+ + + KK +T + +
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491
Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
TLNP +NE F V + L +AV D+D +++IG +V + D H E W
Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550
Query: 261 RDLQSAEKEEQE 272
++ + ++ E
Sbjct: 551 AEMLANPRKPVE 562
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 281 bits (720), Expect = 6e-76
Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)
Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
G++ ++L Y + ++QL+V I+QA +LPA D G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
Query: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260
NPVFNE F F VP +EL + L +VYDFDRFS+HD+IG+ V N ++ + W
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419
Query: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320
RD+ E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK L+
Sbjct: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478
Query: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380
G+RLKK+KT+IKKNTLNP YNE+ F+V E ++ V + + V+DYD IG N+ IG VG
Sbjct: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
Query: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414
++ R HW++MLANPR+P+ WH L E+ V
Sbjct: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573
Score = 79.7 bits (195), Expect = 5e-15
Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)
Query: 29 PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82
PA G D + K+ K+KF ++H+ L P L L +K
Sbjct: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381
Query: 83 CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142
F + + + + ++ +L + D+ L D E G E+
Sbjct: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431
Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
LG+L +SL Y +L V II+A+ L A+D+ G SDPYVK L+ + + KK +T + +
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491
Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
TLNP +NE F V + L +AV D+D +++IG +V + D H E W
Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550
Query: 261 RDLQSAEKEEQE 272
++ + ++ E
Sbjct: 551 AEMLANPRKPVE 562
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 281 bits (720), Expect = 6e-76
Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)
Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
G++ ++L Y + ++QL+V I+QA +LPA D G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360
Query: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260
NPVFNE F F VP +EL + L +VYDFDRFS+HD+IG+ V N ++ + W
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419
Query: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320
RD+ E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK L+
Sbjct: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478
Query: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380
G+RLKK+KT+IKKNTLNP YNE+ F+V E ++ V + + V+DYD IG N+ IG VG
Sbjct: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
Query: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414
++ R HW++MLANPR+P+ WH L E+ V
Sbjct: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573
Score = 79.7 bits (195), Expect = 5e-15
Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)
Query: 29 PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82
PA G D + K+ K+KF ++H+ L P L L +K
Sbjct: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381
Query: 83 CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142
F + + + + ++ +L + D+ L D E G E+
Sbjct: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431
Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
LG+L +SL Y +L V II+A+ L A+D+ G SDPYVK L+ + + KK +T + +
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491
Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
TLNP +NE F V + L +AV D+D +++IG +V + D H E W
Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550
Query: 261 RDLQSAEKEEQE 272
++ + ++ E
Sbjct: 551 AEMLANPRKPVE 562
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 230 bits (586), Expect = 2e-60
Identities = 136/358 (37%), Positives = 210/358 (58%), Gaps = 31/358 (8%)
Query: 81 KKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ--------------ALKDDDAE- 125
KK + K + K G + G + D + G +D+ +K D E
Sbjct: 72 KKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEE 131
Query: 126 -----TGLTDGEEK----EEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALD-MG 175
T LT GE K P+E+ LG L +S+DY+F L+V I +A LP +D
Sbjct: 132 LRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQT 191
Query: 176 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDR 234
SDPY+K+ +LPDK+ + +T+V RKTL+PVF+E FTF +PYS+L L V FDR
Sbjct: 192 QGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDR 251
Query: 235 FSKHDIIGEFKVPMNTVD--FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV 292
FS+ D+IGE VP+ VD G V + RD+ ++ G++ SL Y P A ++TV
Sbjct: 252 FSRDDVIGEVMVPLAGVDPSTGKV-QLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTV 310
Query: 293 VILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFE 351
V+L+A++L KMD+ GLS +PYVK+++ KR+ KKKT +KK TLNP +NESF +++P +
Sbjct: 311 VVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTD 370
Query: 352 QIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNS-TGAELRHWSDMLANPRRPIAQWHTL 408
+ + + V+D+D+ KN+ +G++ +G +S T + HW ++ +PR+P+A+WH+L
Sbjct: 371 LLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 225 bits (574), Expect = 5e-59
Identities = 121/301 (40%), Positives = 183/301 (60%), Gaps = 9/301 (2%)
Query: 123 DAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPA-LDMGGT---- 177
D+ + D EE + +LG L +S YD +N L V +I+A +LP + G+
Sbjct: 165 DSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDM 224
Query: 178 --SDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 235
S+PYVK+ LLPD+K +T V RKT PVF E++TF++P+ E +TL++ V DFD+F
Sbjct: 225 AHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKF 284
Query: 236 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL 295
S+H +IG+ VP+ VD W+ L + + E E LG++ SL Y+P+AG+L V ++
Sbjct: 285 SRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNYLPSAGRLNVDVI 343
Query: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQK 355
AK L + DV SDP+VKI L+ K +K KKT+ + T++P+YNESFSF+VP E+++
Sbjct: 344 RAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELEN 403
Query: 356 VQVVVTVLDYDKIGKNDAIGKVFVG-YNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414
+V TV ++ ND IG++ +G Y+S +E HW ML R + QWH+L+ E
Sbjct: 404 ASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAEC 463
Query: 415 D 415
D
Sbjct: 464 D 464
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 222 bits (566), Expect = 4e-58
Identities = 126/327 (38%), Positives = 193/327 (59%), Gaps = 12/327 (3%)
Query: 85 FKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLG 144
F K N K G +NA ++ +++ ++LK + T LT E+ +EKLG
Sbjct: 105 FPKTNLKPGSPSDLENATPKLFLEGEKESVSPESLK---SSTSLTSEEK------QEKLG 155
Query: 145 KLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
L +SL+Y+F+ +V I +A LPA+D TSDPY+K+ +LP+KK K +T+V RKTL
Sbjct: 156 TLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTL 215
Query: 204 NPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW-R 261
+P F+E FTF +PY+++ L + FDRFS+ DIIGE +P++ ++ R
Sbjct: 216 DPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNR 275
Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
++ + G++ SL Y T LTVV+L+A++L K DV GLSDPYVK++L
Sbjct: 276 EIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAK 335
Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
KR+ KKKT +KK T N +NE F F++P E ++ + V VLD ++ +N+ IG++ +G
Sbjct: 336 KRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGA 395
Query: 382 NSTGAELRHWSDMLANPRRPIAQWHTL 408
+ G HW ++ PRR IA+WH L
Sbjct: 396 AAEGTGGEHWKEICDYPRRQIAKWHVL 422
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 184 bits (466), Expect = 2e-46
Identities = 110/278 (39%), Positives = 151/278 (54%), Gaps = 9/278 (3%)
Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP--DKKKKFETKVHR 200
LG L +SL YD +NN L I +A L +D G +DPYVK+ LLP K K TK R
Sbjct: 127 LGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLR 186
Query: 201 KTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPM------NTVDF 253
TLNP +NE T+ + ++ KTL ++V D D+F ++ IGE +VP+ +T F
Sbjct: 187 NTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTF 246
Query: 254 GHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYV 313
E+ + E + E+ G I SL+Y L V I+ +L MD G SDPYV
Sbjct: 247 NICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYV 306
Query: 314 KIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDA 373
K +L + + K KT +KK TLNP +NE F +E+ + K + VTV DYD ND
Sbjct: 307 KTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDF 366
Query: 374 IGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVE 411
IG V +G ++ G L+HW D L N + I +WHTL E
Sbjct: 367 IGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSE 404
Score = 100 bits (250), Expect = 2e-21
Identities = 51/112 (45%), Positives = 72/112 (64%), Gaps = 2/112 (1%)
Query: 133 EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP--DK 190
+K E K E+ G++ SL Y Q LLVGI++ A L A+D G SDPYVK +L P DK
Sbjct: 257 DKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDK 316
Query: 191 KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIG 242
K K +T V +KTLNP FNE+F +++ + +L K+L + V+D+D +D IG
Sbjct: 317 KSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIG 368
Score = 77.8 bits (190), Expect = 2e-14
Identities = 48/165 (29%), Positives = 81/165 (49%), Gaps = 1/165 (0%)
Query: 258 EEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHL 317
E+ D E ++ LG + FSL Y L I +AK LK MD GL+DPYVK+HL
Sbjct: 111 EDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHL 170
Query: 318 MQNGKRLKKKKTTIKKNTLNPYYNESFS-FEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 376
+ + K +T +NTLNP +NE+ + + + E + + + ++V D DK N+ IG+
Sbjct: 171 LPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGE 230
Query: 377 VFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVK 421
V ++ + P+ + +EE ++++K
Sbjct: 231 TRVPLKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLK 275
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 177 bits (449), Expect = 2e-44
Identities = 102/292 (34%), Positives = 162/292 (55%), Gaps = 16/292 (5%)
Query: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
+D +ET DG LG+L +S++Y+ + +LLVG+I+A L A T P
Sbjct: 136 EDKSETDFPDG----------CLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSP 183
Query: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
VK++LLPD+++ ++K RKT NP F+E F F+V + + L +VY DR KH +
Sbjct: 184 LVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243
Query: 241 IGEFKVPM-NTVDFGHVTEE-WRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
+G+ P+ N G WRDL++ E + GD+ F L Y +LTVV+L AK
Sbjct: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAK 303
Query: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
L+ + G+ +VK+ LM + K +K KKT+ ++NP YNE+FSF+ ++ +
Sbjct: 304 GLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASL 363
Query: 359 VVTVLDYDKIGKNDAIGKVFVG--YNSTGAELRHWSDMLANPRRPIAQWHTL 408
+TV+ + K+ +G+V VG + G EL HW +ML+ P+ + +WH L
Sbjct: 364 SLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 5/151 (3%)
Query: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
+ E E P E G LQ+ L Y+ ++L V +++A L + G +VKV L+
Sbjct: 269 EAESLEPPSE---FGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325
Query: 190 KK--KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP 247
K K +T ++NPV+NE F+FK +EL +L + V K +G V
Sbjct: 326 NKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVG 385
Query: 248 MNTVDFGHVTEEWRDLQSAEKEEQEKLGDIC 278
G E W ++ S KE ++ +C
Sbjct: 386 PYMYTRGRELEHWDEMLSKPKELVKRWHALC 416
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 168 bits (425), Expect = 1e-41
Identities = 112/315 (35%), Positives = 157/315 (49%), Gaps = 33/315 (10%)
Query: 130 DGEEKEEPKEEEK--LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLL 187
DG E + ++ LG L++ L YD + L I++A L +D G +DPYVK+ LL
Sbjct: 75 DGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLL 134
Query: 188 PD--KKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEF 244
P K K +TK R TLNPV+NE T+ + ++ K L +AV D D+ S ++ IGE
Sbjct: 135 PGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEI 194
Query: 245 KVPMNTVD------FGHVTEEW--------------------RDLQSAEKEEQ--EKLGD 276
+VP+ + F E ++L+ AE+ + E+ G
Sbjct: 195 RVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGR 254
Query: 277 ICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL 336
I SL Y L V IL +L MDV G SDPYVK +L + + K KT +KK TL
Sbjct: 255 ILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTL 314
Query: 337 NPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLA 396
NP +NE F +E+ + + VTV DYD ND IG V +G + G +HWSD L
Sbjct: 315 NPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQ 374
Query: 397 NPRRPIAQWHTLQVE 411
P + +WHTL E
Sbjct: 375 QPDAALERWHTLTSE 389
Score = 96.7 bits (239), Expect = 4e-20
Identities = 59/153 (38%), Positives = 83/153 (54%), Gaps = 6/153 (3%)
Query: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP--DKKKKFETKV 198
E+ G++ SL Y + LLVGI++ A L A+D+ G SDPYVK +L P DKK K +T V
Sbjct: 250 EERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCV 309
Query: 199 HRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTE 258
+KTLNP FNE+F +++ S L KTL + V+D+D +D IG V + G +
Sbjct: 310 KKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIG--GVSLGPGARGEARK 367
Query: 259 EWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLT 291
W D E+ + L P AG L+
Sbjct: 368 HWSDCLQQPDAALERWHTLTSEL--PPAAGALS 398
Score = 81.3 bits (199), Expect = 2e-15
Identities = 44/123 (35%), Positives = 69/123 (56%), Gaps = 1/123 (0%)
Query: 258 EEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHL 317
E+ ++ S + ++ LG + F L Y + L IL AK LK MD GL+DPYVK+HL
Sbjct: 74 EDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHL 133
Query: 318 MQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVTVLDYDKIGKNDAIGK 376
+ + K KT ++NTLNP +NE ++ + + I + + V D DK+ N+ IG+
Sbjct: 134 LPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGE 193
Query: 377 VFV 379
+ V
Sbjct: 194 IRV 196
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 167 bits (424), Expect = 1e-41
Identities = 111/320 (34%), Positives = 159/320 (49%), Gaps = 38/320 (11%)
Query: 132 EEKEEPK-----EEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFL 186
EE+EE E LG L++SL YD N+ L II+A L +D G +DPYVK+ L
Sbjct: 377 EEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHL 436
Query: 187 LP--DKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGE 243
LP K K TK R T NP++NE + + ++ KTL ++V D D+F ++ IGE
Sbjct: 437 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 496
Query: 244 FK---------------------VPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDI----- 277
+ +PM T R + E+E+ E++GDI
Sbjct: 497 TRFSLKKLKPNQRKNFNICLERVIPMKRAG---TTGSARGMALYEEEQVERVGDIEERGK 553
Query: 278 -CFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL 336
SL Y G L V I+ +L MD G SDP+VK+ L + + K KT IKK TL
Sbjct: 554 ILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTL 613
Query: 337 NPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLA 396
NP +NE F +++ + K + ++V DYD ND IG +G ++ G L+HW + L
Sbjct: 614 NPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLK 673
Query: 397 NPRRPIAQWHTLQVEEEVDA 416
N + I +WH LQ E V +
Sbjct: 674 NKDKKIERWHQLQNENHVSS 693
Score = 95.5 bits (236), Expect = 8e-20
Identities = 50/117 (42%), Positives = 76/117 (64%), Gaps = 2/117 (1%)
Query: 128 LTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLL 187
L + E+ E + E+ GK+ SL Y Q L+VGII+ L A+D G SDP+VK++L
Sbjct: 536 LYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLK 595
Query: 188 PD--KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIG 242
PD KK K +T++ +KTLNP FNE+F + + +S+L K+L ++V+D+D +D IG
Sbjct: 596 PDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 652
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 167 bits (424), Expect = 1e-41
Identities = 111/320 (34%), Positives = 159/320 (49%), Gaps = 38/320 (11%)
Query: 132 EEKEEPK-----EEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFL 186
EE+EE E LG L++SL YD N+ L II+A L +D G +DPYVK+ L
Sbjct: 373 EEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHL 432
Query: 187 LP--DKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGE 243
LP K K TK R T NP++NE + + ++ KTL ++V D D+F ++ IGE
Sbjct: 433 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 492
Query: 244 FK---------------------VPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDI----- 277
+ +PM T R + E+E+ E++GDI
Sbjct: 493 TRFSLKKLKPNQRKNFNICLERVIPMKRAG---TTGSARGMALYEEEQVERVGDIEERGK 549
Query: 278 -CFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL 336
SL Y G L V I+ +L MD G SDP+VK+ L + + K KT IKK TL
Sbjct: 550 ILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTL 609
Query: 337 NPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLA 396
NP +NE F +++ + K + ++V DYD ND IG +G ++ G L+HW + L
Sbjct: 610 NPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLK 669
Query: 397 NPRRPIAQWHTLQVEEEVDA 416
N + I +WH LQ E V +
Sbjct: 670 NKDKKIERWHQLQNENHVSS 689
Score = 95.5 bits (236), Expect = 8e-20
Identities = 50/117 (42%), Positives = 76/117 (64%), Gaps = 2/117 (1%)
Query: 128 LTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLL 187
L + E+ E + E+ GK+ SL Y Q L+VGII+ L A+D G SDP+VK++L
Sbjct: 532 LYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLK 591
Query: 188 PD--KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIG 242
PD KK K +T++ +KTLNP FNE+F + + +S+L K+L ++V+D+D +D IG
Sbjct: 592 PDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 648
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 160 bits (404), Expect = 3e-39
Identities = 84/268 (31%), Positives = 157/268 (58%), Gaps = 2/268 (0%)
Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 202
LG+++ S++YD ++ L V ++Q +L + +++V LLPD++ +++ R
Sbjct: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212
Query: 203 LNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFG-HVTEEWR 261
+ F+E+F+ + + L K+L +V+ D ++ G ++ ++ +D W
Sbjct: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272
Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
LQ K + +G+I SL Y+PTA +LTVV+++AKNL + +DP+VK++L+Q+G
Sbjct: 273 YLQDQNKAA-DAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331
Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
+++ KKKT +K++ NP +NE+ F VP +Q + + VTV + G+ D +G V +G
Sbjct: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391
Query: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQ 409
+++G HW+ MLA RRP++ WH ++
Sbjct: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419
Score = 56.6 bits (135), Expect = 4e-08
Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 4/132 (3%)
Query: 134 KEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKK- 192
+++ K + +G++ SL Y +L V +++A L + T+DP+VKV+LL D +K
Sbjct: 275 QDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKM 334
Query: 193 -KFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV 251
K +T V R NPVFNE F VP L +L + V + + D +G + +
Sbjct: 335 SKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSAS 394
Query: 252 DFGHVTEEWRDL 263
G T W +
Sbjct: 395 GMG--TTHWNQM 404
>gi|24308233 synaptotagmin XIII [Homo sapiens]
Length = 426
Score = 150 bits (378), Expect = 3e-36
Identities = 87/269 (32%), Positives = 143/269 (53%), Gaps = 6/269 (2%)
Query: 145 KLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKK-KFETKVHRKTL 203
KL Y LDYD Q +L V ++A + G D YV+ + + +T + ++ L
Sbjct: 161 KLHYCLDYDCQKAELFVTRLEAV---TSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQL 217
Query: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDL 263
+ + E + EL TL + + DRFS+H + GE ++ ++ +W +L
Sbjct: 218 HTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGEL 277
Query: 264 QSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGL--SDPYVKIHLMQNG 321
+++ KE G++ S+ Y+P A +L VV+++AKNL L D VK+ L
Sbjct: 278 KTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQA 337
Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
++LKKK+T K+ +NP +NE FE+P + +Q V + VL D G++ A+G +G
Sbjct: 338 RKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGL 397
Query: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQV 410
+++G+E HW +ML NPRR IA WH L +
Sbjct: 398 HTSGSERSHWEEMLKNPRRQIAMWHQLHL 426
>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
Length = 390
Score = 147 bits (372), Expect = 1e-35
Identities = 89/267 (33%), Positives = 146/267 (54%), Gaps = 14/267 (5%)
Query: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
+D +ET DG LG+L +S++Y+ + +LLVG+I+A L A T P
Sbjct: 136 EDKSETDFPDG----------CLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSP 183
Query: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
VK++LLPD+++ ++K RKT NP F+E F F+V + + L +VY DR KH +
Sbjct: 184 LVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243
Query: 241 IGEFKVPM-NTVDFGHVTEE-WRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
+G+ P+ N G WRDL++ E + GD+ F L Y +LTVV+L AK
Sbjct: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAK 303
Query: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
L+ + G+ +VK+ LM + K +K KKT+ ++NP YNE+FSF+ ++ +
Sbjct: 304 GLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASL 363
Query: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTG 385
+TV+ + K ++F+ + ++G
Sbjct: 364 SLTVVQNMEGDKQATTVELFLFHLTSG 390
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 135 bits (339), Expect = 9e-32
Identities = 89/293 (30%), Positives = 145/293 (49%), Gaps = 38/293 (12%)
Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETKVHR 200
G++ +SL Y+ Q L+V + + +L D S+PYVK +LLPDK + K +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
T+NP+++E +++P S L +TL +V+ RF ++ +GE ++ M++ +
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
Query: 261 RDLQSAEKEEQ-----EKLGDICFSLRYVPTA----------------GKLTVVILEAKN 299
L E G++ SL+Y+P + G+L V I EAKN
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
Query: 300 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQV 358
L GG SD +VK +L+ + K+KT + K TLNP+YN +F + V E +Q + +
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
Query: 359 VVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSDMLANP 398
+TV D + + ND +G V +G +STG E+ W M P
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 135 bits (339), Expect = 9e-32
Identities = 89/293 (30%), Positives = 145/293 (49%), Gaps = 38/293 (12%)
Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETKVHR 200
G++ +SL Y+ Q L+V + + +L D S+PYVK +LLPDK + K +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
T+NP+++E +++P S L +TL +V+ RF ++ +GE ++ M++ +
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
Query: 261 RDLQSAEKEEQ-----EKLGDICFSLRYVPTA----------------GKLTVVILEAKN 299
L E G++ SL+Y+P + G+L V I EAKN
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
Query: 300 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQV 358
L GG SD +VK +L+ + K+KT + K TLNP+YN +F + V E +Q + +
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
Query: 359 VVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSDMLANP 398
+TV D + + ND +G V +G +STG E+ W M P
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650
>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
sapiens]
Length = 431
Score = 129 bits (323), Expect = 7e-30
Identities = 94/298 (31%), Positives = 144/298 (48%), Gaps = 20/298 (6%)
Query: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
D E + + + LG L+++L ++ N+ L +A L L G++D YVK LLP
Sbjct: 126 DPEPEGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPL-ASGSADAYVKANLLPG 184
Query: 190 KKKKFETKVH--RKTLNPVFNEQFTF----------KVPYSELGGKTLVMAVYDF-DRFS 236
K + + H R T PV+ E T+ K S+LGG V R
Sbjct: 185 ASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQRQW 244
Query: 237 KHDIIGEFKVPM-----NTVDFGHVTEEWRDLQSAEKEEQ-EKLGDICFSLRYVPTAGKL 290
+ +GE +VP+ N + E R L+ E E E+ G + SL Y G L
Sbjct: 245 QAPSLGELRVPLRKLVPNRARSFDICLEKRRLEEVETEVAWEECGHVLLSLCYSSQQGGL 304
Query: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF 350
V +L +L MD G SDP+V++ L N + K KT++ + TLNP +NE F + P
Sbjct: 305 LVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPR 364
Query: 351 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
E++ + ++V+V DYD +D IG V +G +++G LRHW + L + + WH L
Sbjct: 365 EELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHWLECLGHSDHRLKLWHPL 422
>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
Length = 600
Score = 122 bits (306), Expect = 6e-28
Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%)
Query: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195
+P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ +
Sbjct: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
Query: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244
T + R PVF E F F SE+ G V +Y R K I+GE
Sbjct: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
Query: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290
K+ + + D Q + E E + +I L Y T G+L
Sbjct: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
Query: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349
+ +++ + K + + YVK+ L+ + G+ + K KT+I++ NP Y E+F F+V
Sbjct: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537
Query: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408
Q+ V ++++V + + + + IG + +G NS+G EL HW++M + + + +WH L
Sbjct: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Query: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183
+E ++ + E + ++ L Y+ +L +I+ + L + YVK
Sbjct: 442 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 501
Query: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
+ LL + K +T + R NPV+ E F F+V +L TL+++VY+ + ++
Sbjct: 502 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 561
Query: 241 IGEFKVPMNT---VDFGHVTE 258
IG + +N+ + H TE
Sbjct: 562 IGWISLGLNSSGEEELNHWTE 582
>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
Length = 555
Score = 122 bits (306), Expect = 6e-28
Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%)
Query: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195
+P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ +
Sbjct: 254 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 313
Query: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244
T + R PVF E F F SE+ G V +Y R K I+GE
Sbjct: 314 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 372
Query: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290
K+ + + D Q + E E + +I L Y T G+L
Sbjct: 373 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 432
Query: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349
+ +++ + K + + YVK+ L+ + G+ + K KT+I++ NP Y E+F F+V
Sbjct: 433 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 492
Query: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408
Q+ V ++++V + + + + IG + +G NS+G EL HW++M + + + +WH L
Sbjct: 493 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%)
Query: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183
+E ++ + E + ++ L Y+ +L +I+ + L + YVK
Sbjct: 397 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 456
Query: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
+ LL + K +T + R NPV+ E F F+V +L TL+++VY+ + ++
Sbjct: 457 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 516
Query: 241 IGEFKVPMNT---VDFGHVTE 258
IG + +N+ + H TE
Sbjct: 517 IGWISLGLNSSGEEELNHWTE 537
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,435,738
Number of Sequences: 37866
Number of extensions: 764162
Number of successful extensions: 5300
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 152
Number of HSP's successfully gapped in prelim test: 103
Number of HSP's that attempted gapping in prelim test: 4168
Number of HSP's gapped (non-prelim): 754
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.