Guide to the Human Genome
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Search of human proteins with 209447070

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|209447070 synaptotagmin I [Homo sapiens]
         (422 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|209447073 synaptotagmin I [Homo sapiens]                           852   0.0  
gi|5032139 synaptotagmin I [Homo sapiens]                             852   0.0  
gi|209447070 synaptotagmin I [Homo sapiens]                           852   0.0  
gi|211059429 synaptotagmin II [Homo sapiens]                          649   0.0  
gi|31543670 synaptotagmin II [Homo sapiens]                           649   0.0  
gi|92859638 synaptotagmin V [Homo sapiens]                            474   e-134
gi|45504376 synaptotagmin VI [Homo sapiens]                           298   8e-81
gi|38570146 synaptotagmin VII [Homo sapiens]                          290   2e-78
gi|39752671 synaptotagmin X [Homo sapiens]                            288   5e-78
gi|28376627 synaptotagmin IX [Homo sapiens]                           286   3e-77
gi|94536846 synaptotagmin VIII [Homo sapiens]                         283   2e-76
gi|238550198 synaptotagmin III [Homo sapiens]                         281   6e-76
gi|238550196 synaptotagmin III [Homo sapiens]                         281   6e-76
gi|14150054 synaptotagmin III [Homo sapiens]                          281   6e-76
gi|216548478 synaptotagmin XI [Homo sapiens]                          230   2e-60
gi|40068038 B/K protein [Homo sapiens]                                225   5e-59
gi|24308219 synaptotagmin IV [Homo sapiens]                           222   4e-58
gi|6005997 double C2-like domains, beta [Homo sapiens]                184   2e-46
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                 177   2e-44
gi|47078261 double C2-like domains, alpha [Homo sapiens]              168   1e-41
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            167   1e-41
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             167   1e-41
gi|29366828 synaptotagmin XII [Homo sapiens]                          160   3e-39
gi|24308233 synaptotagmin XIII [Homo sapiens]                         150   3e-36
gi|31881667 synaptotagmin XV isoform b [Homo sapiens]                 147   1e-35
gi|193804862 synaptotagmin-like 4 [Homo sapiens]                      135   9e-32
gi|193804860 synaptotagmin-like 4 [Homo sapiens]                      135   9e-32
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap...   129   7e-30
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]               122   6e-28
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]               122   6e-28

>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  852 bits (2201), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60
           MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
Sbjct: 1   MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60

Query: 61  LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120
           LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
Sbjct: 61  LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120

Query: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
           DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180

Query: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
           YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240

Query: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300
           IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
Sbjct: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300

Query: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360
           KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
Sbjct: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360

Query: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420
           TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
Sbjct: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420

Query: 421 KK 422
           KK
Sbjct: 421 KK 422


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  852 bits (2201), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60
           MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
Sbjct: 1   MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60

Query: 61  LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120
           LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
Sbjct: 61  LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120

Query: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
           DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180

Query: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
           YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240

Query: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300
           IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
Sbjct: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300

Query: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360
           KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
Sbjct: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360

Query: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420
           TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
Sbjct: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420

Query: 421 KK 422
           KK
Sbjct: 421 KK 422


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  852 bits (2201), Expect = 0.0
 Identities = 422/422 (100%), Positives = 422/422 (100%)

Query: 1   MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60
           MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA
Sbjct: 1   MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 60

Query: 61  LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120
           LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK
Sbjct: 61  LIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALK 120

Query: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
           DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP
Sbjct: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180

Query: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
           YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI
Sbjct: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240

Query: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300
           IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL
Sbjct: 241 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 300

Query: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360
           KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV
Sbjct: 301 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 360

Query: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420
           TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV
Sbjct: 361 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 420

Query: 421 KK 422
           KK
Sbjct: 421 KK 422


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  649 bits (1674), Expect = 0.0
 Identities = 324/424 (76%), Positives = 354/424 (83%), Gaps = 11/424 (2%)

Query: 2   VSESHHEALAAPPVTTVATVLP--SNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPW 59
           + + + E + AP  TT    +    N+TE    GE +ED F+KLKEK  NE++KIPLPPW
Sbjct: 4   IFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPW 63

Query: 60  ALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 119
           ALIAIA+VA LL+LTCCFCICKKC  KKK  KK K KG KNA+NMKD+K           
Sbjct: 64  ALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG--------GQ 115

Query: 120 KDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTS 178
            DDDAETGLT+GE E EE KE E LGKLQ+SLDYDFQ NQL VG++QAAELPALDMGGTS
Sbjct: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175

Query: 179 DPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKH 238
           DPYVKVFLLPDKKKK+ETKVHRKTLNP FNE FTFKVPY ELGGKTLVMA+YDFDRFSKH
Sbjct: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235

Query: 239 DIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
           DIIGE KVPMNTVD G   EEWRDLQ  EKEE EKLGDIC SLRYVPTAGKLTV ILEAK
Sbjct: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295

Query: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
           NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT+KK TLNPY+NESFSFE+PFEQIQKVQV
Sbjct: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355

Query: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAML 418
           VVTVLDYDK+GKN+AIGK+FVG N+TG ELRHWSDMLANPRRPIAQWH+L+ EEEVDA+L
Sbjct: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415

Query: 419 AVKK 422
              K
Sbjct: 416 GKNK 419


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  649 bits (1674), Expect = 0.0
 Identities = 324/424 (76%), Positives = 354/424 (83%), Gaps = 11/424 (2%)

Query: 2   VSESHHEALAAPPVTTVATVLP--SNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPW 59
           + + + E + AP  TT    +    N+TE    GE +ED F+KLKEK  NE++KIPLPPW
Sbjct: 4   IFKRNQEPIVAPATTTATMPIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPW 63

Query: 60  ALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 119
           ALIAIA+VA LL+LTCCFCICKKC  KKK  KK K KG KNA+NMKD+K           
Sbjct: 64  ALIAIAVVAGLLLLTCCFCICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG--------GQ 115

Query: 120 KDDDAETGLTDGE-EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTS 178
            DDDAETGLT+GE E EE KE E LGKLQ+SLDYDFQ NQL VG++QAAELPALDMGGTS
Sbjct: 116 DDDDAETGLTEGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTS 175

Query: 179 DPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKH 238
           DPYVKVFLLPDKKKK+ETKVHRKTLNP FNE FTFKVPY ELGGKTLVMA+YDFDRFSKH
Sbjct: 176 DPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKH 235

Query: 239 DIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
           DIIGE KVPMNTVD G   EEWRDLQ  EKEE EKLGDIC SLRYVPTAGKLTV ILEAK
Sbjct: 236 DIIGEVKVPMNTVDLGQPIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAK 295

Query: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
           NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTT+KK TLNPY+NESFSFE+PFEQIQKVQV
Sbjct: 296 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQV 355

Query: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAML 418
           VVTVLDYDK+GKN+AIGK+FVG N+TG ELRHWSDMLANPRRPIAQWH+L+ EEEVDA+L
Sbjct: 356 VVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALL 415

Query: 419 AVKK 422
              K
Sbjct: 416 GKNK 419


>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score =  474 bits (1221), Expect = e-134
 Identities = 231/387 (59%), Positives = 299/387 (77%), Gaps = 10/387 (2%)

Query: 28  EPASPGEGKEDAFSKLKEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKKCLFKK 87
           EP +PG    D          + +   P+PPWAL  I +V+ LL+ +CCFC+ +K     
Sbjct: 4   EPPTPGPPSPDT-----PPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSC--- 55

Query: 88  KNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQ 147
             ++ GK+   +  +++++VK LG++  D+   + +       G  ++   + E LG+LQ
Sbjct: 56  -RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHE-LGRLQ 113

Query: 148 YSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVF 207
           YSLDYDFQ+ QLLVGI+QA  L ALD+GG+SDPYV+V+LLPDK++++ETKVHR+TLNP F
Sbjct: 114 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF 173

Query: 208 NEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAE 267
            E F FKVPY ELGG+ LVMAVYDFDRFS++D IGE +VPM++VD G   + WR+LQ+A 
Sbjct: 174 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP 233

Query: 268 KEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKK 327
           +EEQEKLGDICFSLRYVPTAGKLTV++LEAKNLKKMDVGGLSDPYVK+HL+Q GK+++KK
Sbjct: 234 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK 293

Query: 328 KTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAE 387
           KTTIKKNTLNPYYNE+FSFEVP +Q+QKVQV +TVLDYDK+GKN+AIG+V VG  + GA 
Sbjct: 294 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG 353

Query: 388 LRHWSDMLANPRRPIAQWHTLQVEEEV 414
           LRHW+DMLANPRRPIAQWH+L+  + V
Sbjct: 354 LRHWADMLANPRRPIAQWHSLRPPDRV 380


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  298 bits (762), Expect = 8e-81
 Identities = 142/281 (50%), Positives = 202/281 (71%), Gaps = 4/281 (1%)

Query: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
           DGE+ +  +  +  GK+ +SL YD++   L+V I++A +LPA D  G+SDPYVK++LLPD
Sbjct: 133 DGEDAKS-EATKSCGKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPD 191

Query: 190 KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP-- 247
           +K K +T+VHRKTLNP F+E F F VPY EL  + L ++V+DFDRFS+HD+IGE  +   
Sbjct: 192 RKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNL 251

Query: 248 MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGG 307
               D    T  W+D+Q A  E  + LG+I FSL Y+PTAG+LT+ +++ +NLK MD+ G
Sbjct: 252 FEASDLSRETSIWKDIQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITG 310

Query: 308 LSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDK 367
            SDPYVK+ L+ +G+RLKKKKTTIKKNTLNP YNE+  F++P E + +V ++++V+DYD+
Sbjct: 311 YSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDR 370

Query: 368 IGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
           +G N+ IG   VG  + G    HW++MLA PR+PIA WH+L
Sbjct: 371 VGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411


>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  290 bits (742), Expect = 2e-78
 Identities = 155/388 (39%), Positives = 232/388 (59%), Gaps = 42/388 (10%)

Query: 61  LIAIAIVAVLLVLTCCFC-ICKKCLFK--------------------KKNKKKGKEKGGK 99
           L+  AI+ V L +T   C +C  C  K                    +  KK  K   G 
Sbjct: 18  LLVSAIITVSLSVTVVLCGLCHWCQRKLGKRYKNSLETVGTPDSGRGRSEKKAIKLPAGG 77

Query: 100 NAINMKDVKDLGKTMKDQALKDDDAETGLTD--------------GEEKEEPKE---EEK 142
            A+N   V   G+T  D++ +  +  + ++D              G E++E  E    E 
Sbjct: 78  KAVNTAPVP--GQTPHDESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEEDEAHEGCSREN 135

Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 202
           LG++Q+S+ Y+FQ + L V I++A ELPA D  GTSDP+VK++LLPDKK K ETKV RK 
Sbjct: 136 LGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKN 195

Query: 203 LNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWR 261
           LNP +NE F F+  PY ++  + L + V D+DRFS++D IGE  +P+N VD   +   W+
Sbjct: 196 LNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWK 255

Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
           DL+        + G++  SL Y P+A  + V I++A+NLK MD+GG SDPYVK+ LM   
Sbjct: 256 DLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKD 314

Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
           KR++KKKT   K  LNP +NESF+F++P E++++  +++TV+D DK+ +ND IGK+++ +
Sbjct: 315 KRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSW 374

Query: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQ 409
            S   E++HW DM+A PR+P+AQWH L+
Sbjct: 375 KSGPGEVKHWKDMIARPRQPVAQWHQLK 402


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  288 bits (738), Expect = 5e-78
 Identities = 139/282 (49%), Positives = 195/282 (69%), Gaps = 6/282 (2%)

Query: 129 TDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP 188
           ++G + E+ K     GKL ++L YD++N  L+V II+A +LPA D  GTSDPYVK++LLP
Sbjct: 221 SEGNQNEDVKI---CGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLP 277

Query: 189 DKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP- 247
           D+KKKF+T+VHRKTLNP+F+E F F V Y +L  + L  +VYDFDRFS+HD+IGE  +  
Sbjct: 278 DRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDN 337

Query: 248 -MNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVG 306
                D       W+D+  A  E  + LG+I FSL Y+PTAG++T+ +++ +NLK MD+ 
Sbjct: 338 LFEVSDLSREATVWKDIHCATTESID-LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDIT 396

Query: 307 GLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYD 366
           G SDPYVK+ LM  G+RLKK+KTT KKNTLNP YNE+  F++P E + +V + + V+DYD
Sbjct: 397 GSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYD 456

Query: 367 KIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
           ++G N+ IG    G ++ G    HW++MLA  R+PI  WH L
Sbjct: 457 RVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWHPL 498



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 40/118 (33%), Positives = 72/118 (61%), Gaps = 2/118 (1%)

Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
           D +  + E+ +  G + F+L+Y      L V I++A +L   D  G SDPYVK++L+ + 
Sbjct: 220 DSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPD- 278

Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFV 379
            R KK +T + + TLNP ++E+F F V ++Q+   ++  +V D+D+  ++D IG+V +
Sbjct: 279 -RKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL 335


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score =  286 bits (731), Expect = 3e-77
 Identities = 138/267 (51%), Positives = 190/267 (71%), Gaps = 3/267 (1%)

Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
           GKL + L YD    QL+V I +A  LPA D  GTSDPYVK++LLPD+K K +TKVHRKTL
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281

Query: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP--MNTVDFGHVTEEWR 261
           NPVF+E F F VPY++L  + L  +VYDFDRFS+HD+IG+  V   ++  DF      W+
Sbjct: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWK 341

Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
           D++    +  + LG++ FSL Y+PTAG+LT+ I++A+NLK MD+ G SDPYVK+ LM +G
Sbjct: 342 DIEYVTNDNVD-LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400

Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
           +RLKK+KT+ K+NTLNP YNE+  F+VP E I ++ + + V+DYD++G N+ IG   VG 
Sbjct: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460

Query: 382 NSTGAELRHWSDMLANPRRPIAQWHTL 408
            +      HWS+ML+ PR+PIA WH+L
Sbjct: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 50/125 (40%), Positives = 70/125 (56%), Gaps = 4/125 (3%)

Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
           LG+L +SL Y     +L + II+A  L A+D+ G SDPYVKV L+ D  + KK +T   R
Sbjct: 353 LGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKR 412

Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
            TLNPV+NE   F VP   +    L +AV D+DR   ++IIG  +V       G   + W
Sbjct: 413 NTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGR--DHW 470

Query: 261 RDLQS 265
            ++ S
Sbjct: 471 SEMLS 475



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 41/120 (34%), Positives = 67/120 (55%), Gaps = 2/120 (1%)

Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
           D     +   +  G + F L+Y     +L V I +A NL   D  G SDPYVKI+L+ + 
Sbjct: 209 DNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD- 267

Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
            R  K +T + + TLNP ++E F F VP+  ++  ++  +V D+D+  ++D IG+V V +
Sbjct: 268 -RKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDH 326


>gi|94536846 synaptotagmin VIII [Homo sapiens]
          Length = 401

 Score =  283 bits (725), Expect = 2e-76
 Identities = 155/367 (42%), Positives = 226/367 (61%), Gaps = 22/367 (5%)

Query: 55  PLPPWALIAIAIVAVLLVLTCCFCICKKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTM 114
           P P WALIA A+ A +L+++C  C    C  + + K + KE  G  +         G T 
Sbjct: 45  PWPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSAR-------GTTT 97

Query: 115 KDQALKDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDM 174
                 D D   GL     +  P + ++ G+LQ SL++DF + ++ VG+ QAA+L     
Sbjct: 98  THLVQPDVD---GL-----ESSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADLRP--- 146

Query: 175 GGTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDR 234
           GGT DPY +V +      + ETKVHR TL PVF+E   F +P +EL G TL + +++F R
Sbjct: 147 GGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKR 206

Query: 235 FSKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVI 294
           FS H+ +GE ++P+ TVD  HV E W  L      + E++G++CFSLRYVP++G+LTVV+
Sbjct: 207 FSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVV 266

Query: 295 LEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQ 354
           LEA+ L+     GL++PYVK+ LM N ++ KK+KT  KK T  PY+NE+F+F VPF Q+Q
Sbjct: 267 LEARGLRP----GLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQ 322

Query: 355 KVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414
            V +V+ V D     + + +GKV +G  ++G  L+HW+DMLA+ RRPIAQ H L+   EV
Sbjct: 323 NVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREV 382

Query: 415 DAMLAVK 421
           D MLA++
Sbjct: 383 DRMLALQ 389


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  281 bits (720), Expect = 6e-76
 Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)

Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
           G++ ++L Y + ++QL+V I+QA +LPA D  G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360

Query: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260
           NPVFNE F F VP +EL  + L  +VYDFDRFS+HD+IG+  V  N ++      +   W
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419

Query: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320
           RD+     E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK  L+  
Sbjct: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478

Query: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380
           G+RLKK+KT+IKKNTLNP YNE+  F+V  E ++ V + + V+DYD IG N+ IG   VG
Sbjct: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538

Query: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414
            ++     R HW++MLANPR+P+  WH L  E+ V
Sbjct: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573



 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)

Query: 29  PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82
           PA    G  D + K+      K+KF  ++H+  L P           L  L       +K
Sbjct: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381

Query: 83  CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142
             F   +  +         + + ++ +L +   D+ L  D  E G           E+  
Sbjct: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431

Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
           LG+L +SL Y     +L V II+A+ L A+D+ G SDPYVK  L+ +  + KK +T + +
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491

Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
            TLNP +NE   F V    +    L +AV D+D    +++IG  +V  +  D  H  E W
Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550

Query: 261 RDLQSAEKEEQE 272
            ++ +  ++  E
Sbjct: 551 AEMLANPRKPVE 562


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  281 bits (720), Expect = 6e-76
 Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)

Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
           G++ ++L Y + ++QL+V I+QA +LPA D  G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360

Query: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260
           NPVFNE F F VP +EL  + L  +VYDFDRFS+HD+IG+  V  N ++      +   W
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419

Query: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320
           RD+     E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK  L+  
Sbjct: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478

Query: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380
           G+RLKK+KT+IKKNTLNP YNE+  F+V  E ++ V + + V+DYD IG N+ IG   VG
Sbjct: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538

Query: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414
            ++     R HW++MLANPR+P+  WH L  E+ V
Sbjct: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573



 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)

Query: 29  PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82
           PA    G  D + K+      K+KF  ++H+  L P           L  L       +K
Sbjct: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381

Query: 83  CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142
             F   +  +         + + ++ +L +   D+ L  D  E G           E+  
Sbjct: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431

Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
           LG+L +SL Y     +L V II+A+ L A+D+ G SDPYVK  L+ +  + KK +T + +
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491

Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
            TLNP +NE   F V    +    L +AV D+D    +++IG  +V  +  D  H  E W
Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550

Query: 261 RDLQSAEKEEQE 272
            ++ +  ++  E
Sbjct: 551 AEMLANPRKPVE 562


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  281 bits (720), Expect = 6e-76
 Identities = 143/275 (52%), Positives = 195/275 (70%), Gaps = 6/275 (2%)

Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
           G++ ++L Y + ++QL+V I+QA +LPA D  G SDPYVK++LLPD+KKKF+TKVHRKTL
Sbjct: 301 GRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTL 360

Query: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEE---W 260
           NPVFNE F F VP +EL  + L  +VYDFDRFS+HD+IG+  V  N ++      +   W
Sbjct: 361 NPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV-VLDNLLELAEQPPDRPLW 419

Query: 261 RDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQN 320
           RD+     E+ + LG++ FSL Y+PTAG+LTV I++A NLK MD+ G SDPYVK  L+  
Sbjct: 420 RDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISE 478

Query: 321 GKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVG 380
           G+RLKK+KT+IKKNTLNP YNE+  F+V  E ++ V + + V+DYD IG N+ IG   VG
Sbjct: 479 GRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538

Query: 381 YNSTGAELR-HWSDMLANPRRPIAQWHTLQVEEEV 414
            ++     R HW++MLANPR+P+  WH L  E+ V
Sbjct: 539 PDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTV 573



 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 68/252 (26%), Positives = 112/252 (44%), Gaps = 24/252 (9%)

Query: 29  PASPGEGKEDAFSKL------KEKFMNELHKIPLPPWALIAIAIVAVLLVLTCCFCICKK 82
           PA    G  D + K+      K+KF  ++H+  L P           L  L       +K
Sbjct: 327 PAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLAELAQ-----RK 381

Query: 83  CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEK 142
             F   +  +         + + ++ +L +   D+ L  D  E G           E+  
Sbjct: 382 LHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDRPLWRDIVEGG----------SEKAD 431

Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD--KKKKFETKVHR 200
           LG+L +SL Y     +L V II+A+ L A+D+ G SDPYVK  L+ +  + KK +T + +
Sbjct: 432 LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKK 491

Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
            TLNP +NE   F V    +    L +AV D+D    +++IG  +V  +  D  H  E W
Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAAD-PHGREHW 550

Query: 261 RDLQSAEKEEQE 272
            ++ +  ++  E
Sbjct: 551 AEMLANPRKPVE 562


>gi|216548478 synaptotagmin XI [Homo sapiens]
          Length = 431

 Score =  230 bits (586), Expect = 2e-60
 Identities = 136/358 (37%), Positives = 210/358 (58%), Gaps = 31/358 (8%)

Query: 81  KKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ--------------ALKDDDAE- 125
           KK + K +  K G  + G     + D  + G   +D+               +K D  E 
Sbjct: 72  KKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEE 131

Query: 126 -----TGLTDGEEK----EEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALD-MG 175
                T LT GE K      P+E+  LG L +S+DY+F    L+V I +A  LP +D   
Sbjct: 132 LRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQT 191

Query: 176 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDR 234
             SDPY+K+ +LPDK+ + +T+V RKTL+PVF+E FTF  +PYS+L    L   V  FDR
Sbjct: 192 QGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDR 251

Query: 235 FSKHDIIGEFKVPMNTVD--FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV 292
           FS+ D+IGE  VP+  VD   G V +  RD+     ++    G++  SL Y P A ++TV
Sbjct: 252 FSRDDVIGEVMVPLAGVDPSTGKV-QLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTV 310

Query: 293 VILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFE 351
           V+L+A++L KMD+ GLS +PYVK+++    KR+ KKKT +KK TLNP +NESF +++P +
Sbjct: 311 VVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTD 370

Query: 352 QIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNS-TGAELRHWSDMLANPRRPIAQWHTL 408
            +  + +   V+D+D+  KN+ +G++ +G +S T +   HW ++  +PR+P+A+WH+L
Sbjct: 371 LLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428


>gi|40068038 B/K protein [Homo sapiens]
          Length = 474

 Score =  225 bits (574), Expect = 5e-59
 Identities = 121/301 (40%), Positives = 183/301 (60%), Gaps = 9/301 (2%)

Query: 123 DAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPA-LDMGGT---- 177
           D+ +   D    EE   + +LG L +S  YD  +N L V +I+A +LP  +   G+    
Sbjct: 165 DSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDM 224

Query: 178 --SDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRF 235
             S+PYVK+ LLPD+K   +T V RKT  PVF E++TF++P+ E   +TL++ V DFD+F
Sbjct: 225 AHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKF 284

Query: 236 SKHDIIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVIL 295
           S+H +IG+  VP+  VD       W+ L  + + E E LG++  SL Y+P+AG+L V ++
Sbjct: 285 SRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVE-LGELLLSLNYLPSAGRLNVDVI 343

Query: 296 EAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQK 355
            AK L + DV   SDP+VKI L+   K +K KKT+  + T++P+YNESFSF+VP E+++ 
Sbjct: 344 RAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELEN 403

Query: 356 VQVVVTVLDYDKIGKNDAIGKVFVG-YNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEV 414
             +V TV  ++    ND IG++ +G Y+S  +E  HW  ML   R  + QWH+L+   E 
Sbjct: 404 ASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSLRSRAEC 463

Query: 415 D 415
           D
Sbjct: 464 D 464


>gi|24308219 synaptotagmin IV [Homo sapiens]
          Length = 425

 Score =  222 bits (566), Expect = 4e-58
 Identities = 126/327 (38%), Positives = 193/327 (59%), Gaps = 12/327 (3%)

Query: 85  FKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQALKDDDAETGLTDGEEKEEPKEEEKLG 144
           F K N K G     +NA     ++   +++  ++LK   + T LT  E+      +EKLG
Sbjct: 105 FPKTNLKPGSPSDLENATPKLFLEGEKESVSPESLK---SSTSLTSEEK------QEKLG 155

Query: 145 KLQYSLDYDFQNNQLLVGIIQAAELPALD-MGGTSDPYVKVFLLPDKKKKFETKVHRKTL 203
            L +SL+Y+F+    +V I +A  LPA+D    TSDPY+K+ +LP+KK K +T+V RKTL
Sbjct: 156 TLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTL 215

Query: 204 NPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW-R 261
           +P F+E FTF  +PY+++    L   +  FDRFS+ DIIGE  +P++ ++         R
Sbjct: 216 DPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNR 275

Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
           ++      +    G++  SL Y  T   LTVV+L+A++L K DV GLSDPYVK++L    
Sbjct: 276 EIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAK 335

Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
           KR+ KKKT +KK T N  +NE F F++P E ++ + V   VLD ++  +N+ IG++ +G 
Sbjct: 336 KRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGA 395

Query: 382 NSTGAELRHWSDMLANPRRPIAQWHTL 408
            + G    HW ++   PRR IA+WH L
Sbjct: 396 AAEGTGGEHWKEICDYPRRQIAKWHVL 422


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score =  184 bits (466), Expect = 2e-46
 Identities = 110/278 (39%), Positives = 151/278 (54%), Gaps = 9/278 (3%)

Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP--DKKKKFETKVHR 200
           LG L +SL YD +NN L   I +A  L  +D  G +DPYVK+ LLP   K  K  TK  R
Sbjct: 127 LGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLR 186

Query: 201 KTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPM------NTVDF 253
            TLNP +NE  T+  +   ++  KTL ++V D D+F  ++ IGE +VP+      +T  F
Sbjct: 187 NTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTF 246

Query: 254 GHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYV 313
               E+   +   E +  E+ G I  SL+Y      L V I+   +L  MD  G SDPYV
Sbjct: 247 NICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYV 306

Query: 314 KIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDA 373
           K +L  +  +  K KT +KK TLNP +NE F +E+    + K  + VTV DYD    ND 
Sbjct: 307 KTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDF 366

Query: 374 IGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVE 411
           IG V +G ++ G  L+HW D L N  + I +WHTL  E
Sbjct: 367 IGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTLTSE 404



 Score =  100 bits (250), Expect = 2e-21
 Identities = 51/112 (45%), Positives = 72/112 (64%), Gaps = 2/112 (1%)

Query: 133 EKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP--DK 190
           +K E K  E+ G++  SL Y  Q   LLVGI++ A L A+D  G SDPYVK +L P  DK
Sbjct: 257 DKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDK 316

Query: 191 KKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIG 242
           K K +T V +KTLNP FNE+F +++ + +L  K+L + V+D+D    +D IG
Sbjct: 317 KSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIG 368



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 48/165 (29%), Positives = 81/165 (49%), Gaps = 1/165 (0%)

Query: 258 EEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHL 317
           E+  D    E ++   LG + FSL Y      L   I +AK LK MD  GL+DPYVK+HL
Sbjct: 111 EDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHL 170

Query: 318 MQNGKRLKKKKTTIKKNTLNPYYNESFS-FEVPFEQIQKVQVVVTVLDYDKIGKNDAIGK 376
           +    +  K +T   +NTLNP +NE+ + + +  E + +  + ++V D DK   N+ IG+
Sbjct: 171 LPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGE 230

Query: 377 VFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAVK 421
             V             ++    + P+ +     +EE    ++++K
Sbjct: 231 TRVPLKKLKPNHTKTFNICLEKQLPVDKTEDKSLEERGRILISLK 275


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score =  177 bits (449), Expect = 2e-44
 Identities = 102/292 (34%), Positives = 162/292 (55%), Gaps = 16/292 (5%)

Query: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
           +D +ET   DG           LG+L +S++Y+ +  +LLVG+I+A  L A     T  P
Sbjct: 136 EDKSETDFPDG----------CLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSP 183

Query: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
            VK++LLPD+++  ++K  RKT NP F+E F F+V    +  + L  +VY  DR  KH +
Sbjct: 184 LVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243

Query: 241 IGEFKVPM-NTVDFGHVTEE-WRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
           +G+   P+ N    G      WRDL++   E   + GD+ F L Y     +LTVV+L AK
Sbjct: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAK 303

Query: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
            L+  +  G+   +VK+ LM + K +K KKT+    ++NP YNE+FSF+    ++    +
Sbjct: 304 GLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASL 363

Query: 359 VVTVLDYDKIGKNDAIGKVFVG--YNSTGAELRHWSDMLANPRRPIAQWHTL 408
            +TV+   +  K+  +G+V VG    + G EL HW +ML+ P+  + +WH L
Sbjct: 364 SLTVVQNMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 5/151 (3%)

Query: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
           + E  E P E    G LQ+ L Y+   ++L V +++A  L   +  G    +VKV L+  
Sbjct: 269 EAESLEPPSE---FGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIVSVFVKVSLMNH 325

Query: 190 KK--KKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVP 247
            K  K  +T     ++NPV+NE F+FK   +EL   +L + V       K   +G   V 
Sbjct: 326 NKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVG 385

Query: 248 MNTVDFGHVTEEWRDLQSAEKEEQEKLGDIC 278
                 G   E W ++ S  KE  ++   +C
Sbjct: 386 PYMYTRGRELEHWDEMLSKPKELVKRWHALC 416


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score =  168 bits (425), Expect = 1e-41
 Identities = 112/315 (35%), Positives = 157/315 (49%), Gaps = 33/315 (10%)

Query: 130 DGEEKEEPKEEEK--LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLL 187
           DG E +    ++   LG L++ L YD  +  L   I++A  L  +D  G +DPYVK+ LL
Sbjct: 75  DGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLL 134

Query: 188 PD--KKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGEF 244
           P   K  K +TK  R TLNPV+NE  T+  +   ++  K L +AV D D+ S ++ IGE 
Sbjct: 135 PGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEI 194

Query: 245 KVPMNTVD------FGHVTEEW--------------------RDLQSAEKEEQ--EKLGD 276
           +VP+  +       F    E                      ++L+ AE+ +   E+ G 
Sbjct: 195 RVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGR 254

Query: 277 ICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL 336
           I  SL Y      L V IL   +L  MDV G SDPYVK +L  +  +  K KT +KK TL
Sbjct: 255 ILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTL 314

Query: 337 NPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLA 396
           NP +NE F +E+    +    + VTV DYD    ND IG V +G  + G   +HWSD L 
Sbjct: 315 NPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQ 374

Query: 397 NPRRPIAQWHTLQVE 411
            P   + +WHTL  E
Sbjct: 375 QPDAALERWHTLTSE 389



 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 59/153 (38%), Positives = 83/153 (54%), Gaps = 6/153 (3%)

Query: 141 EKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLP--DKKKKFETKV 198
           E+ G++  SL Y  +   LLVGI++ A L A+D+ G SDPYVK +L P  DKK K +T V
Sbjct: 250 EERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCV 309

Query: 199 HRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTE 258
            +KTLNP FNE+F +++  S L  KTL + V+D+D    +D IG   V +     G   +
Sbjct: 310 KKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIG--GVSLGPGARGEARK 367

Query: 259 EWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLT 291
            W D         E+   +   L   P AG L+
Sbjct: 368 HWSDCLQQPDAALERWHTLTSEL--PPAAGALS 398



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 44/123 (35%), Positives = 69/123 (56%), Gaps = 1/123 (0%)

Query: 258 EEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHL 317
           E+  ++ S + ++   LG + F L Y   +  L   IL AK LK MD  GL+DPYVK+HL
Sbjct: 74  EDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHL 133

Query: 318 MQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQVVVTVLDYDKIGKNDAIGK 376
           +    +  K KT  ++NTLNP +NE  ++  +  + I    + + V D DK+  N+ IG+
Sbjct: 134 LPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGE 193

Query: 377 VFV 379
           + V
Sbjct: 194 IRV 196


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  167 bits (424), Expect = 1e-41
 Identities = 111/320 (34%), Positives = 159/320 (49%), Gaps = 38/320 (11%)

Query: 132 EEKEEPK-----EEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFL 186
           EE+EE       E   LG L++SL YD  N+ L   II+A  L  +D  G +DPYVK+ L
Sbjct: 377 EEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHL 436

Query: 187 LP--DKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGE 243
           LP   K  K  TK  R T NP++NE   +  +   ++  KTL ++V D D+F  ++ IGE
Sbjct: 437 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 496

Query: 244 FK---------------------VPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDI----- 277
            +                     +PM        T   R +   E+E+ E++GDI     
Sbjct: 497 TRFSLKKLKPNQRKNFNICLERVIPMKRAG---TTGSARGMALYEEEQVERVGDIEERGK 553

Query: 278 -CFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL 336
              SL Y    G L V I+   +L  MD  G SDP+VK+ L  +  +  K KT IKK TL
Sbjct: 554 ILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTL 613

Query: 337 NPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLA 396
           NP +NE F +++    + K  + ++V DYD    ND IG   +G ++ G  L+HW + L 
Sbjct: 614 NPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLK 673

Query: 397 NPRRPIAQWHTLQVEEEVDA 416
           N  + I +WH LQ E  V +
Sbjct: 674 NKDKKIERWHQLQNENHVSS 693



 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 50/117 (42%), Positives = 76/117 (64%), Gaps = 2/117 (1%)

Query: 128 LTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLL 187
           L + E+ E   + E+ GK+  SL Y  Q   L+VGII+   L A+D  G SDP+VK++L 
Sbjct: 536 LYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLK 595

Query: 188 PD--KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIG 242
           PD  KK K +T++ +KTLNP FNE+F + + +S+L  K+L ++V+D+D    +D IG
Sbjct: 596 PDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 652


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  167 bits (424), Expect = 1e-41
 Identities = 111/320 (34%), Positives = 159/320 (49%), Gaps = 38/320 (11%)

Query: 132 EEKEEPK-----EEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFL 186
           EE+EE       E   LG L++SL YD  N+ L   II+A  L  +D  G +DPYVK+ L
Sbjct: 373 EEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHL 432

Query: 187 LP--DKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGE 243
           LP   K  K  TK  R T NP++NE   +  +   ++  KTL ++V D D+F  ++ IGE
Sbjct: 433 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 492

Query: 244 FK---------------------VPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDI----- 277
            +                     +PM        T   R +   E+E+ E++GDI     
Sbjct: 493 TRFSLKKLKPNQRKNFNICLERVIPMKRAG---TTGSARGMALYEEEQVERVGDIEERGK 549

Query: 278 -CFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL 336
              SL Y    G L V I+   +L  MD  G SDP+VK+ L  +  +  K KT IKK TL
Sbjct: 550 ILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTL 609

Query: 337 NPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLA 396
           NP +NE F +++    + K  + ++V DYD    ND IG   +G ++ G  L+HW + L 
Sbjct: 610 NPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLK 669

Query: 397 NPRRPIAQWHTLQVEEEVDA 416
           N  + I +WH LQ E  V +
Sbjct: 670 NKDKKIERWHQLQNENHVSS 689



 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 50/117 (42%), Positives = 76/117 (64%), Gaps = 2/117 (1%)

Query: 128 LTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLL 187
           L + E+ E   + E+ GK+  SL Y  Q   L+VGII+   L A+D  G SDP+VK++L 
Sbjct: 532 LYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLK 591

Query: 188 PD--KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIG 242
           PD  KK K +T++ +KTLNP FNE+F + + +S+L  K+L ++V+D+D    +D IG
Sbjct: 592 PDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 648


>gi|29366828 synaptotagmin XII [Homo sapiens]
          Length = 421

 Score =  160 bits (404), Expect = 3e-39
 Identities = 84/268 (31%), Positives = 157/268 (58%), Gaps = 2/268 (0%)

Query: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 202
           LG+++ S++YD  ++ L V ++Q  +L   +       +++V LLPD++    +++ R  
Sbjct: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212

Query: 203 LNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFG-HVTEEWR 261
            +  F+E+F+  +  + L  K+L  +V+  D   ++   G  ++ ++ +D        W 
Sbjct: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272

Query: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321
            LQ   K   + +G+I  SL Y+PTA +LTVV+++AKNL   +    +DP+VK++L+Q+G
Sbjct: 273 YLQDQNKAA-DAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331

Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
           +++ KKKT +K++  NP +NE+  F VP   +Q + + VTV +    G+ D +G V +G 
Sbjct: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391

Query: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQ 409
           +++G    HW+ MLA  RRP++ WH ++
Sbjct: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 4/132 (3%)

Query: 134 KEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKK- 192
           +++ K  + +G++  SL Y     +L V +++A  L   +   T+DP+VKV+LL D +K 
Sbjct: 275 QDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKM 334

Query: 193 -KFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV 251
            K +T V R   NPVFNE   F VP   L   +L + V +     + D +G   +  +  
Sbjct: 335 SKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSAS 394

Query: 252 DFGHVTEEWRDL 263
             G  T  W  +
Sbjct: 395 GMG--TTHWNQM 404


>gi|24308233 synaptotagmin XIII [Homo sapiens]
          Length = 426

 Score =  150 bits (378), Expect = 3e-36
 Identities = 87/269 (32%), Positives = 143/269 (53%), Gaps = 6/269 (2%)

Query: 145 KLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKK-KFETKVHRKTL 203
           KL Y LDYD Q  +L V  ++A      +  G  D YV+  +       + +T + ++ L
Sbjct: 161 KLHYCLDYDCQKAELFVTRLEAV---TSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQL 217

Query: 204 NPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEWRDL 263
           +  + E     +   EL   TL + +   DRFS+H + GE ++ ++         +W +L
Sbjct: 218 HTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGEL 277

Query: 264 QSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGL--SDPYVKIHLMQNG 321
           +++ KE     G++  S+ Y+P A +L VV+++AKNL       L   D  VK+ L    
Sbjct: 278 KTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQA 337

Query: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381
           ++LKKK+T   K+ +NP +NE   FE+P + +Q   V + VL  D  G++ A+G   +G 
Sbjct: 338 RKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGL 397

Query: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQV 410
           +++G+E  HW +ML NPRR IA WH L +
Sbjct: 398 HTSGSERSHWEEMLKNPRRQIAMWHQLHL 426


>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
          Length = 390

 Score =  147 bits (372), Expect = 1e-35
 Identities = 89/267 (33%), Positives = 146/267 (54%), Gaps = 14/267 (5%)

Query: 121 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 180
           +D +ET   DG           LG+L +S++Y+ +  +LLVG+I+A  L A     T  P
Sbjct: 136 EDKSETDFPDG----------CLGRLWFSVEYEQEAERLLVGLIKAQHLQA--PSETCSP 183

Query: 181 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
            VK++LLPD+++  ++K  RKT NP F+E F F+V    +  + L  +VY  DR  KH +
Sbjct: 184 LVKLYLLPDERRFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQL 243

Query: 241 IGEFKVPM-NTVDFGHVTEE-WRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAK 298
           +G+   P+ N    G      WRDL++   E   + GD+ F L Y     +LTVV+L AK
Sbjct: 244 LGQVLFPLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAK 303

Query: 299 NLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQV 358
            L+  +  G+   +VK+ LM + K +K KKT+    ++NP YNE+FSF+    ++    +
Sbjct: 304 GLRLQEDRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASL 363

Query: 359 VVTVLDYDKIGKNDAIGKVFVGYNSTG 385
            +TV+   +  K     ++F+ + ++G
Sbjct: 364 SLTVVQNMEGDKQATTVELFLFHLTSG 390


>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  135 bits (339), Expect = 9e-32
 Identities = 89/293 (30%), Positives = 145/293 (49%), Gaps = 38/293 (12%)

Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETKVHR 200
           G++ +SL Y+ Q   L+V + +  +L   D     S+PYVK +LLPDK +  K +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
            T+NP+++E   +++P S L  +TL  +V+   RF ++  +GE ++ M++       +  
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477

Query: 261 RDLQSAEKEEQ-----EKLGDICFSLRYVPTA----------------GKLTVVILEAKN 299
             L      E         G++  SL+Y+P +                G+L V I EAKN
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 300 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQV 358
           L     GG SD +VK +L+    +  K+KT + K TLNP+YN +F +  V  E +Q + +
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 359 VVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSDMLANP 398
            +TV D + +  ND +G V +G              +STG E+  W  M   P
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650


>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
          Length = 671

 Score =  135 bits (339), Expect = 9e-32
 Identities = 89/293 (30%), Positives = 145/293 (49%), Gaps = 38/293 (12%)

Query: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETKVHR 200
           G++ +SL Y+ Q   L+V + +  +L   D     S+PYVK +LLPDK +  K +T + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417

Query: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
            T+NP+++E   +++P S L  +TL  +V+   RF ++  +GE ++ M++       +  
Sbjct: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477

Query: 261 RDLQSAEKEEQ-----EKLGDICFSLRYVPTA----------------GKLTVVILEAKN 299
             L      E         G++  SL+Y+P +                G+L V I EAKN
Sbjct: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537

Query: 300 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQV 358
           L     GG SD +VK +L+    +  K+KT + K TLNP+YN +F +  V  E +Q + +
Sbjct: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597

Query: 359 VVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSDMLANP 398
            +TV D + +  ND +G V +G              +STG E+  W  M   P
Sbjct: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650


>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
           sapiens]
          Length = 431

 Score =  129 bits (323), Expect = 7e-30
 Identities = 94/298 (31%), Positives = 144/298 (48%), Gaps = 20/298 (6%)

Query: 130 DGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPD 189
           D E + +  +   LG L+++L ++  N+ L     +A  L  L   G++D YVK  LLP 
Sbjct: 126 DPEPEGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPL-ASGSADAYVKANLLPG 184

Query: 190 KKKKFETKVH--RKTLNPVFNEQFTF----------KVPYSELGGKTLVMAVYDF-DRFS 236
             K  + + H  R T  PV+ E  T+          K   S+LGG   V        R  
Sbjct: 185 ASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQRQW 244

Query: 237 KHDIIGEFKVPM-----NTVDFGHVTEEWRDLQSAEKEEQ-EKLGDICFSLRYVPTAGKL 290
           +   +GE +VP+     N      +  E R L+  E E   E+ G +  SL Y    G L
Sbjct: 245 QAPSLGELRVPLRKLVPNRARSFDICLEKRRLEEVETEVAWEECGHVLLSLCYSSQQGGL 304

Query: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPF 350
            V +L   +L  MD  G SDP+V++ L  N  +  K KT++ + TLNP +NE F +  P 
Sbjct: 305 LVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPR 364

Query: 351 EQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTL 408
           E++ +  ++V+V DYD    +D IG V +G +++G  LRHW + L +    +  WH L
Sbjct: 365 EELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHWLECLGHSDHRLKLWHPL 422


>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
          Length = 600

 Score =  122 bits (306), Expect = 6e-28
 Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%)

Query: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195
           +P+ E K G L  + DYD Q  +LLV +    ++P  +  G +   V + LLP KK++ +
Sbjct: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358

Query: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244
           T + R    PVF E F F    SE+ G   V   +Y   R  K  I+GE           
Sbjct: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417

Query: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290
            K+ +  +          D Q +  E             E   + +I   L Y  T G+L
Sbjct: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477

Query: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349
           +  +++  + K +      + YVK+ L+ + G+ + K KT+I++   NP Y E+F F+V 
Sbjct: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537

Query: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408
             Q+  V ++++V +   + + + IG + +G NS+G  EL HW++M  +  + + +WH L
Sbjct: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%)

Query: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183
           +E   ++     +  E   + ++   L Y+    +L   +I+ +    L      + YVK
Sbjct: 442 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 501

Query: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
           + LL     +  K +T + R   NPV+ E F F+V   +L   TL+++VY+     + ++
Sbjct: 502 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 561

Query: 241 IGEFKVPMNT---VDFGHVTE 258
           IG   + +N+    +  H TE
Sbjct: 562 IGWISLGLNSSGEEELNHWTE 582


>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
          Length = 555

 Score =  122 bits (306), Expect = 6e-28
 Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%)

Query: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195
           +P+ E K G L  + DYD Q  +LLV +    ++P  +  G +   V + LLP KK++ +
Sbjct: 254 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 313

Query: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244
           T + R    PVF E F F    SE+ G   V   +Y   R  K  I+GE           
Sbjct: 314 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 372

Query: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290
            K+ +  +          D Q +  E             E   + +I   L Y  T G+L
Sbjct: 373 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 432

Query: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349
           +  +++  + K +      + YVK+ L+ + G+ + K KT+I++   NP Y E+F F+V 
Sbjct: 433 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 492

Query: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408
             Q+  V ++++V +   + + + IG + +G NS+G  EL HW++M  +  + + +WH L
Sbjct: 493 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%)

Query: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183
           +E   ++     +  E   + ++   L Y+    +L   +I+ +    L      + YVK
Sbjct: 397 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 456

Query: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240
           + LL     +  K +T + R   NPV+ E F F+V   +L   TL+++VY+     + ++
Sbjct: 457 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 516

Query: 241 IGEFKVPMNT---VDFGHVTE 258
           IG   + +N+    +  H TE
Sbjct: 517 IGWISLGLNSSGEEELNHWTE 537


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,435,738
Number of Sequences: 37866
Number of extensions: 764162
Number of successful extensions: 5300
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 152
Number of HSP's successfully gapped in prelim test: 103
Number of HSP's that attempted gapping in prelim test: 4168
Number of HSP's gapped (non-prelim): 754
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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