BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo sapiens] (1015 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 2029 0.0 gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 2014 0.0 gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 1909 0.0 gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 1629 0.0 gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 1629 0.0 gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 1496 0.0 gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 1496 0.0 gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 1496 0.0 gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 1496 0.0 gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 1496 0.0 gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 1496 0.0 gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 1496 0.0 gi|239751049 PREDICTED: similar to ATPase, Ca++ transporting, fa... 936 0.0 gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 442 e-123 gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 442 e-123 gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 441 e-123 gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 431 e-120 gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 404 e-112 gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 344 3e-94 gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 343 4e-94 gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 341 2e-93 gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 333 4e-91 gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 330 5e-90 gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 330 5e-90 gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 330 5e-90 gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 308 1e-83 gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 276 9e-74 gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 271 3e-72 gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 271 3e-72 gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 257 4e-68 >gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo sapiens] Length = 1015 Score = 2029 bits (5257), Expect = 0.0 Identities = 1015/1015 (100%), Positives = 1015/1015 (100%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL Sbjct: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAGESVSVIKHTDPVPDPRAVNQDKKNM 180 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAGESVSVIKHTDPVPDPRAVNQDKKNM Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAGESVSVIKHTDPVPDPRAVNQDKKNM 180 Query: 181 LFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLI 240 LFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLI Sbjct: 181 LFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLI 240 Query: 241 CIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 300 CIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA Sbjct: 241 CIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMA 300 Query: 301 KKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGS 360 KKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGS Sbjct: 301 KKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGS 360 Query: 361 TYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTC 420 TYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTC Sbjct: 361 TYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTC 420 Query: 421 LVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTS 480 LVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTS Sbjct: 421 LVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTS 480 Query: 481 MSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHD 540 MSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHD Sbjct: 481 MSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHD 540 Query: 541 NPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDN 600 NPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDN Sbjct: 541 NPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDN 600 Query: 601 KGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKIV 660 KGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKIV Sbjct: 601 KGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKIV 660 Query: 661 EFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVE 720 EFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVE Sbjct: 661 EFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVE 720 Query: 721 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 780 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG Sbjct: 721 EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALG 780 Query: 781 FNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFY 840 FNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFY Sbjct: 781 FNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFY 840 Query: 841 QLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPW 900 QLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPW Sbjct: 841 QLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPW 900 Query: 901 ENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVA 960 ENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVA Sbjct: 901 ENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVA 960 Query: 961 RNYLEPGKECVQPATKSCSFSACTDGISWPFVLLIMPLVIWVYSTDTNFSDMFWS 1015 RNYLEPGKECVQPATKSCSFSACTDGISWPFVLLIMPLVIWVYSTDTNFSDMFWS Sbjct: 961 RNYLEPGKECVQPATKSCSFSACTDGISWPFVLLIMPLVIWVYSTDTNFSDMFWS 1015 >gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo sapiens] Length = 1042 Score = 2014 bits (5219), Expect = 0.0 Identities = 1015/1042 (97%), Positives = 1015/1042 (97%), Gaps = 27/1042 (2%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL Sbjct: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC Sbjct: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 513 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV Sbjct: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 540 Query: 514 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 573 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD Sbjct: 541 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 600 Query: 574 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL 633 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL Sbjct: 601 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL 660 Query: 634 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG 693 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG Sbjct: 661 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG 720 Query: 694 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 753 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL Sbjct: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 Query: 754 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 813 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG Sbjct: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 Query: 814 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 873 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL Sbjct: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 Query: 874 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 933 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP Sbjct: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 Query: 934 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL 993 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL Sbjct: 961 LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL 1020 Query: 994 LIMPLVIWVYSTDTNFSDMFWS 1015 LIMPLVIWVYSTDTNFSDMFWS Sbjct: 1021 LIMPLVIWVYSTDTNFSDMFWS 1042 >gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo sapiens] Length = 997 Score = 1909 bits (4945), Expect = 0.0 Identities = 966/993 (97%), Positives = 966/993 (97%), Gaps = 27/993 (2%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL Sbjct: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC Sbjct: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 513 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV Sbjct: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 540 Query: 514 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 573 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD Sbjct: 541 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 600 Query: 574 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL 633 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL Sbjct: 601 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL 660 Query: 634 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG 693 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG Sbjct: 661 NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG 720 Query: 694 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 753 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL Sbjct: 721 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 780 Query: 754 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 813 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG Sbjct: 781 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 840 Query: 814 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 873 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL Sbjct: 841 CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL 900 Query: 874 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 933 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP Sbjct: 901 SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP 960 Query: 934 LNVTQWLMVLKISLPVILMDETLKFVARNYLEP 966 LNVTQWLMVLKISLPVILMDETLKFVARNYLEP Sbjct: 961 LNVTQWLMVLKISLPVILMDETLKFVARNYLEP 993 >gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo sapiens] Length = 994 Score = 1629 bits (4219), Expect = 0.0 Identities = 814/993 (81%), Positives = 899/993 (90%), Gaps = 28/993 (2%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH KT EE L +FGV+E+TGL+ +QVK+ E++G NELPAEEGKTL ELVIEQFEDL Sbjct: 1 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+A Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V TGV TEIGKIRD+M Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV Sbjct: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV QYDGLVELATICALC Sbjct: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK Sbjct: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512 KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T Sbjct: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540 Query: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 572 VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YET+LTFVG VGML Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600 Query: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 632 DPPR EV S++LCR AGIRVIMITGDNKGTA+AICRRIGIFG++E+V +A+TGREFD+ Sbjct: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660 Query: 633 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 692 L + QR+AC A CFARVEPSHKSKIVE+LQS+DEITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 693 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 752 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA Sbjct: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780 Query: 753 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 812 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++PPR+PKEPLISGWLFFRY+AI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840 Query: 813 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 872 G YVGAATVGAAAWWF+ A+ GP V++ QL+HF+QC EDN FEG+DC +FE+P PMTMA Sbjct: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900 Query: 873 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 932 LSVLVTIEMCNALNSLSENQSLLRMPPW NIWL+GSICLSMSLHFLILYV+PLP+IF++ Sbjct: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960 Query: 933 PLNVTQWLMVLKISLPVILMDETLKFVARNYLE 965 L++TQWLMVLKISLPVI +DE LKFVARNYLE Sbjct: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLE 993 >gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo sapiens] Length = 1001 Score = 1629 bits (4219), Expect = 0.0 Identities = 814/993 (81%), Positives = 899/993 (90%), Gaps = 28/993 (2%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH KT EE L +FGV+E+TGL+ +QVK+ E++G NELPAEEGKTL ELVIEQFEDL Sbjct: 1 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK Sbjct: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+A Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V TGV TEIGKIRD+M Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV Sbjct: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV QYDGLVELATICALC Sbjct: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK Sbjct: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512 KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T Sbjct: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540 Query: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 572 VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YET+LTFVG VGML Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600 Query: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 632 DPPR EV S++LCR AGIRVIMITGDNKGTA+AICRRIGIFG++E+V +A+TGREFD+ Sbjct: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660 Query: 633 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 692 L + QR+AC A CFARVEPSHKSKIVE+LQS+DEITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 693 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 752 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA Sbjct: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780 Query: 753 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 812 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++PPR+PKEPLISGWLFFRY+AI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840 Query: 813 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 872 G YVGAATVGAAAWWF+ A+ GP V++ QL+HF+QC EDN FEG+DC +FE+P PMTMA Sbjct: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900 Query: 873 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 932 LSVLVTIEMCNALNSLSENQSLLRMPPW NIWL+GSICLSMSLHFLILYV+PLP+IF++ Sbjct: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960 Query: 933 PLNVTQWLMVLKISLPVILMDETLKFVARNYLE 965 L++TQWLMVLKISLPVI +DE LKFVARNYLE Sbjct: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLE 993 >gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 1496 bits (3874), Expect = 0.0 Identities = 745/1001 (74%), Positives = 850/1001 (84%), Gaps = 31/1001 (3%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+A Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 572 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 632 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 633 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 692 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 693 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 752 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 753 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 812 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 813 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 872 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 873 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 932 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 933 PLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 973 PL+ QW++VL+ISLPVIL+DE LK+++RN++ C+ P Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHMH---ACLYP 998 >gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 1496 bits (3874), Expect = 0.0 Identities = 745/1001 (74%), Positives = 850/1001 (84%), Gaps = 31/1001 (3%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+A Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 572 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 632 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 633 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 692 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 693 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 752 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 753 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 812 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 813 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 872 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 873 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 932 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 933 PLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 973 PL+ QW++VL+ISLPVIL+DE LK+++RN++ C+ P Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHMH---ACLYP 998 >gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo sapiens] Length = 1043 Score = 1496 bits (3874), Expect = 0.0 Identities = 745/1001 (74%), Positives = 850/1001 (84%), Gaps = 31/1001 (3%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+A Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 572 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 632 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 633 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 692 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 693 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 752 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 753 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 812 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 813 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 872 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 873 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 932 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 933 PLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 973 PL+ QW++VL+ISLPVIL+DE LK+++RN++ C+ P Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHMH---ACLYP 998 >gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo sapiens] Length = 1044 Score = 1496 bits (3874), Expect = 0.0 Identities = 745/1001 (74%), Positives = 850/1001 (84%), Gaps = 31/1001 (3%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+A Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 572 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 632 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 633 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 692 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 693 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 752 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 753 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 812 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 813 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 872 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 873 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 932 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 933 PLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 973 PL+ QW++VL+ISLPVIL+DE LK+++RN++ C+ P Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHMH---ACLYP 998 >gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo sapiens] Length = 1052 Score = 1496 bits (3874), Expect = 0.0 Identities = 745/1001 (74%), Positives = 850/1001 (84%), Gaps = 31/1001 (3%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+A Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 572 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 632 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 633 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 692 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 693 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 752 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 753 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 812 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 813 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 872 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 873 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 932 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 933 PLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQP 973 PL+ QW++VL+ISLPVIL+DE LK+++RN++ C+ P Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHMH---ACLYP 998 >gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo sapiens] Length = 999 Score = 1496 bits (3873), Expect = 0.0 Identities = 743/992 (74%), Positives = 847/992 (85%), Gaps = 28/992 (2%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+A Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 572 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 632 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 633 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 692 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 693 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 752 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 753 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 812 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 813 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 872 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 873 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 932 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 933 PLNVTQWLMVLKISLPVILMDETLKFVARNYL 964 PL+ QW++VL+ISLPVIL+DE LK+++RN++ Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992 >gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo sapiens] Length = 998 Score = 1496 bits (3873), Expect = 0.0 Identities = 743/992 (74%), Positives = 847/992 (85%), Gaps = 28/992 (2%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH +VL HF V GLS QV +ER+G NELP+EEGK+L ELV+EQFEDL Sbjct: 1 MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LILVANAIVGVWQERNAE+AIEALK Sbjct: 61 LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKV R DRK VQRI+A+DIVPGDIVE+A Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSV KHT+ +PDPRAVNQDKKNMLFSGTNI +GKA+GV VATG++TE+GKIR +M Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 A E ERTPLQ+KLDEFG QLS IS+IC+AVW+INIGHF DP HGGSW+RGA+YYFKIAV Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVCRMF++ + +C L+EFTI+G+TY P GEV + D+PV C Q+DGLVELATICALC Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDT+L+ LS++ERA ACN+VIKQLM+ Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512 KEFTLEFSRDRKSMSVYCTP +P T SKMFVKGAPE VI+RC+ +RVGS P+T Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540 Query: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 572 +++I++ IR+WGSGSDTLRCLALAT D P R+E+M L+D + F++YET+LTFVGCVGML Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600 Query: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 632 DPPR EVA+ + C QAGIRV+MITGDNKGTAVAICRR+GIFG EDV KA+TGREFD+ Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660 Query: 633 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 692 L+P QR AC ARCFARVEP+HKS+IVE LQSF+EITAMTGDGVNDAPALKKAEIGIAM Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720 Query: 693 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 752 GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780 Query: 753 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 812 LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM K PR+P+E LISGWLFFRYLAI Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840 Query: 813 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 872 G YVG ATV AA WWF+ GP ++FYQL +FL+C EDNP F G+DC +FES +P TMA Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900 Query: 873 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 932 LSVLVTIEMCNALNS+SENQSLLRMPPW N WL+ ++ +SM+LHFLIL V PLPLIFQ+T Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960 Query: 933 PLNVTQWLMVLKISLPVILMDETLKFVARNYL 964 PL+ QW++VL+ISLPVIL+DE LK+++RN++ Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992 >gi|239751049 PREDICTED: similar to ATPase, Ca++ transporting, fast twitch 1 [Homo sapiens] Length = 879 Score = 936 bits (2420), Expect = 0.0 Identities = 473/590 (80%), Positives = 524/590 (88%), Gaps = 28/590 (4%) Query: 1 MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 ME AH KT EE L +FGV+E+TGL+ +QVK+ E++G NELPAEEGKTL ELVIEQFEDL Sbjct: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK Sbjct: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154 EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+A Sbjct: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435 Query: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213 GESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V TGV TEIGKIRD+M Sbjct: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495 Query: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273 ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV Sbjct: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555 Query: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ Sbjct: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615 Query: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV QYDGLVELATICALC Sbjct: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675 Query: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453 NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK Sbjct: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735 Query: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512 KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T Sbjct: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795 Query: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN 562 VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YE + Sbjct: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYEVS 845 >gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens] Length = 949 Score = 442 bits (1136), Expect = e-123 Identities = 326/1004 (32%), Positives = 494/1004 (49%), Gaps = 150/1004 (14%) Query: 9 VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68 V EV + GL+ +V + G NE E + L + I QF++ L+ +LL + Sbjct: 31 VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90 Query: 69 ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128 A IS ++ F++ V V +LI+V A V QE +E ++E L + P Sbjct: 91 AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140 Query: 129 VYRQDRKSVQRIKAKDIVPGDIV------------------EIAGESVSVIKHTDP---- 166 R+ + ++ A+D+VPGD V +++ + S+ T P Sbjct: 141 CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKV 198 Query: 167 -VPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPL 222 P P A N D + N+ F GT + GKA GVV+ TG N+E G++ M A E +TPL Sbjct: 199 TAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPL 258 Query: 223 QQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278 Q+ +D G+QLS +I +I + W++ + + F I+V+LAVA Sbjct: 259 QKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVA 304 Query: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338 AIPEGLP V+T LALG RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V Sbjct: 305 AIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTH 364 Query: 339 MFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSAL 398 +F D + + +TG Y GEV D V+ + + +CND+ + Sbjct: 365 IFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVI 416 Query: 399 DYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTL 458 N +G+ TE AL L KM L GL + + K E+ Sbjct: 417 RNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKAEYP- 453 Query: 459 EFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIM 518 FS ++K M+V C ++ + F+KGA E VI CT + + +T +Q+ + Sbjct: 454 -FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--QQRDV 509 Query: 519 SVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIE 578 + GS LR LALA+ LTF+G VG++DPPR Sbjct: 510 YQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDPPRTG 551 Query: 579 VASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQ 638 V +V +G+ + MITGD++ TAVAI R+G++ + TS++ +G E D ++ Sbjct: 552 VKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMDVQQL 607 Query: 639 RDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTA 697 F R P HK KI++ LQ + AMTGDGVNDA ALK A+IG+AMG +GT Sbjct: 608 SQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTD 667 Query: 698 VAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPE 757 V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++ + I L + FP Sbjct: 668 VCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPN 727 Query: 758 ALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVG 817 L +Q+LW+N++ DG PA +LG P D D++ KPPRN K+ +++ L + L + Sbjct: 728 PLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIV 787 Query: 818 AATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLV 877 T L F + DN +P TM + V Sbjct: 788 CGT---------------------LFVFWRELRDN----------VITPRDTTMTFTCFV 816 Query: 878 TIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVT 937 +M NAL+S S+ +S+ + N ++ S+ L++Y PL +FQ L++ Sbjct: 817 FFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSIL 876 Query: 938 QWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFS 981 L +L ++ V ++ E +K V R+ +E +Q S S S Sbjct: 877 DLLFLLGLTSSVCIVAEIIKKVERS-----REKIQKHVSSTSSS 915 >gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens] Length = 919 Score = 442 bits (1136), Expect = e-123 Identities = 326/1004 (32%), Positives = 494/1004 (49%), Gaps = 150/1004 (14%) Query: 9 VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68 V EV + GL+ +V + G NE E + L + I QF++ L+ +LL + Sbjct: 31 VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90 Query: 69 ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128 A IS ++ F++ V V +LI+V A V QE +E ++E L + P Sbjct: 91 AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140 Query: 129 VYRQDRKSVQRIKAKDIVPGDIV------------------EIAGESVSVIKHTDP---- 166 R+ + ++ A+D+VPGD V +++ + S+ T P Sbjct: 141 CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKV 198 Query: 167 -VPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPL 222 P P A N D + N+ F GT + GKA GVV+ TG N+E G++ M A E +TPL Sbjct: 199 TAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPL 258 Query: 223 QQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278 Q+ +D G+QLS +I +I + W++ + + F I+V+LAVA Sbjct: 259 QKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVA 304 Query: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338 AIPEGLP V+T LALG RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V Sbjct: 305 AIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTH 364 Query: 339 MFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSAL 398 +F D + + +TG Y GEV D V+ + + +CND+ + Sbjct: 365 IFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVI 416 Query: 399 DYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTL 458 N +G+ TE AL L KM L GL + + K E+ Sbjct: 417 RNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKAEYP- 453 Query: 459 EFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIM 518 FS ++K M+V C ++ + F+KGA E VI CT + + +T +Q+ + Sbjct: 454 -FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--QQRDV 509 Query: 519 SVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIE 578 + GS LR LALA+ LTF+G VG++DPPR Sbjct: 510 YQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDPPRTG 551 Query: 579 VASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQ 638 V +V +G+ + MITGD++ TAVAI R+G++ + TS++ +G E D ++ Sbjct: 552 VKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMDVQQL 607 Query: 639 RDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTA 697 F R P HK KI++ LQ + AMTGDGVNDA ALK A+IG+AMG +GT Sbjct: 608 SQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTD 667 Query: 698 VAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPE 757 V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++ + I L + FP Sbjct: 668 VCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPN 727 Query: 758 ALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVG 817 L +Q+LW+N++ DG PA +LG P D D++ KPPRN K+ +++ L + L + Sbjct: 728 PLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIV 787 Query: 818 AATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLV 877 T L F + DN +P TM + V Sbjct: 788 CGT---------------------LFVFWRELRDN----------VITPRDTTMTFTCFV 816 Query: 878 TIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVT 937 +M NAL+S S+ +S+ + N ++ S+ L++Y PL +FQ L++ Sbjct: 817 FFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSIL 876 Query: 938 QWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFS 981 L +L ++ V ++ E +K V R+ +E +Q S S S Sbjct: 877 DLLFLLGLTSSVCIVAEIIKKVERS-----REKIQKHVSSTSSS 915 >gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens] Length = 939 Score = 441 bits (1134), Expect = e-123 Identities = 321/985 (32%), Positives = 487/985 (49%), Gaps = 145/985 (14%) Query: 9 VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68 V EV + GL+ +V + G NE E + L + I QF++ L+ +LL + Sbjct: 31 VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90 Query: 69 ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128 A IS ++ F++ V V +LI+V A V QE +E ++E L + P Sbjct: 91 AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140 Query: 129 VYRQDRKSVQRIKAKDIVPGDIV------------------EIAGESVSVIKHTDP---- 166 R+ + ++ A+D+VPGD V +++ + S+ T P Sbjct: 141 CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKV 198 Query: 167 -VPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPL 222 P P A N D + N+ F GT + GKA GVV+ TG N+E G++ M A E +TPL Sbjct: 199 TAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPL 258 Query: 223 QQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278 Q+ +D G+QLS +I +I + W++ + + F I+V+LAVA Sbjct: 259 QKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVA 304 Query: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338 AIPEGLP V+T LALG RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V Sbjct: 305 AIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTH 364 Query: 339 MFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSAL 398 +F D + + +TG Y GEV D V+ + + +CND+ + Sbjct: 365 IFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVI 416 Query: 399 DYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTL 458 N +G+ TE AL L KM L GL + + K E+ Sbjct: 417 RNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKAEYP- 453 Query: 459 EFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIM 518 FS ++K M+V C ++ + F+KGA E VI CT + + +T +Q+ + Sbjct: 454 -FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--QQRDV 509 Query: 519 SVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIE 578 + GS LR LALA+ LTF+G VG++DPPR Sbjct: 510 YQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDPPRTG 551 Query: 579 VASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQ 638 V +V +G+ + MITGD++ TAVAI R+G++ + TS++ +G E D ++ Sbjct: 552 VKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMDVQQL 607 Query: 639 RDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTA 697 F R P HK KI++ LQ + AMTGDGVNDA ALK A+IG+AMG +GT Sbjct: 608 SQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTD 667 Query: 698 VAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPE 757 V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++ + I L + FP Sbjct: 668 VCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPN 727 Query: 758 ALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVG 817 L +Q+LW+N++ DG PA +LG P D D++ KPPRN K+ +++ L + L + Sbjct: 728 PLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIV 787 Query: 818 AATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLV 877 T L F + DN +P TM + V Sbjct: 788 CGT---------------------LFVFWRELRDN----------VITPRDTTMTFTCFV 816 Query: 878 TIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVT 937 +M NAL+S S+ +S+ + N ++ S+ L++Y PL +FQ L++ Sbjct: 817 FFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSIL 876 Query: 938 QWLMVLKISLPVILMDETLKFVARN 962 L +L ++ V ++ E +K V R+ Sbjct: 877 DLLFLLGLTSSVCIVAEIIKKVERS 901 >gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens] Length = 888 Score = 431 bits (1109), Expect = e-120 Identities = 314/959 (32%), Positives = 473/959 (49%), Gaps = 145/959 (15%) Query: 9 VEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLA 68 V EV + GL+ +V + G NE E + L + I QF++ L+ +LL + Sbjct: 31 VSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLAS 90 Query: 69 ACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK 128 A IS ++ F++ V V +LI+V A V QE +E ++E L + P Sbjct: 91 AVISVLMHQFDDA-------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECH 140 Query: 129 VYRQDRKSVQRIKAKDIVPGDIV------------------EIAGESVSVIKHTDP---- 166 R+ + ++ A+D+VPGD V +++ + S+ T P Sbjct: 141 CVREGK--LEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKV 198 Query: 167 -VPDPRAVNQD---KKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPL 222 P P A N D + N+ F GT + GKA GVV+ TG N+E G++ M A E +TPL Sbjct: 199 TAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPL 258 Query: 223 QQKLDEFGEQLS----KVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278 Q+ +D G+QLS +I +I + W++ + + F I+V+LAVA Sbjct: 259 QKSMDLLGKQLSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVA 304 Query: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338 AIPEGLP V+T LALG RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V Sbjct: 305 AIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTH 364 Query: 339 MFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSAL 398 +F D + + +TG Y GEV D V+ + + +CND+ + Sbjct: 365 IFTSDGLHAE--------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVI 416 Query: 399 DYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTL 458 N +G+ TE AL L KM L GL + + K E+ Sbjct: 417 RNNTL------MGKPTEGALIALAMKMG-----LDGLQQ-----------DYIRKAEYP- 453 Query: 459 EFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIM 518 FS ++K M+V C ++ + F+KGA E VI CT + + +T +Q+ + Sbjct: 454 -FSSEQKWMAVKCV-HRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQ--QQRDV 509 Query: 519 SVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIE 578 + GS LR LALA+ LTF+G VG++DPPR Sbjct: 510 YQQEKARMGSAGLRVLALASGPEL------------------GQLTFLGLVGIIDPPRTG 551 Query: 579 VASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQ 638 V +V +G+ + MITGD++ TAVAI R+G++ + TS++ +G E D ++ Sbjct: 552 VKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSK----TSQSVSGEEIDAMDVQQL 607 Query: 639 RDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTA 697 F R P HK KI++ LQ + AMTGDGVNDA ALK A+IG+AMG +GT Sbjct: 608 SQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTD 667 Query: 698 VAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPE 757 V K A++M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++ + I L + FP Sbjct: 668 VCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPN 727 Query: 758 ALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVG 817 L +Q+LW+N++ DG PA +LG P D D++ KPPRN K+ +++ L + L + Sbjct: 728 PLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIV 787 Query: 818 AATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLV 877 T L F + DN +P TM + V Sbjct: 788 CGT---------------------LFVFWRELRDN----------VITPRDTTMTFTCFV 816 Query: 878 TIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNV 936 +M NAL+S S+ +S+ + N ++ S+ L++Y PL +FQ L++ Sbjct: 817 FFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSI 875 >gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo sapiens] Length = 946 Score = 404 bits (1037), Expect = e-112 Identities = 307/993 (30%), Positives = 484/993 (48%), Gaps = 141/993 (14%) Query: 10 EEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAA 69 E++ F V+ TGLS V + + G NE A+ + + + ++QF++ L+ +LL +A Sbjct: 63 EDLARAFCVDLHTGLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLLLGSA 122 Query: 70 CISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKV 129 +S + +E+ TA +L++V A + QE +E ++E L + P Sbjct: 123 LVSVLTKEYEDAVSIATA-------VLVVVTVAFI---QEYRSEKSLEELTKMVPPECNC 172 Query: 130 YRQDRKSVQRIKAKDIVPGDIVEIA-----GESVSVIKHTDPVPDPRAVNQDKK------ 178 R+ + +Q + A+++VPGD+V ++ + + + TD + D + + + Sbjct: 173 LREGK--LQHLLARELVPGDVVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTD 230 Query: 179 -------------NMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQK 225 N++F GT + G+ GVV+ TG +++ G++ M A E +TPLQ+ Sbjct: 231 SPLTGGGDLTTLSNIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPLQKS 290 Query: 226 LDEFGEQLSK----VISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIP 281 +D G+QL+ +I LI + W S + + F I V+LAVAAIP Sbjct: 291 MDRLGKQLTLFSFGIIGLIMLIGW--------------SQGKQLLSMFTIGVSLAVAAIP 336 Query: 282 EGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFI 341 EGLP V+ L LG RMAKK IV+ LP VETLGC SV+CSDKTGTLT N+M+V ++ Sbjct: 337 EGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVT 396 Query: 342 LDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYN 401 D + + + P EV K+ V+ + LVE + N++ + N Sbjct: 397 SDGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGK---LVEAGCVA---NNAVIRKN 450 Query: 402 EAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFS 461 +G+ TE AL L KM++ D + NS I+ KKE + FS Sbjct: 451 AV------MGQPTEGALMALAMKMDLSDIK-------------NSYIR---KKE--IPFS 486 Query: 462 RDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVI 521 ++K M+V C+ + + F+KGA E VI CT G +P+T +Q+ + Sbjct: 487 SEQKWMAVKCSLKTEDQEDI--YFMKGALEEVIRYCTMYNNGGIPLPLTP--QQRSFCLQ 542 Query: 522 REWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVAS 581 E GS LR LALA+ R LTF+G VG++DPPR+ V Sbjct: 543 EEKRMGSLGLRVLALASGPELGR------------------LTFLGLVGIIDPPRVGVKE 584 Query: 582 SVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDA 641 +V++ ++G+ V MITGD TA+AI R IG+ +A +G E D + D Sbjct: 585 AVQVLSESGVSVKMITGDALETALAIGRNIGLCNGK----LQAMSGEEVDSVEKGELADR 640 Query: 642 CLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAK 700 F R P HK KI++ LQ I AMTGDGVNDA ALK A+IGIAMG +GT V+K Sbjct: 641 VGKVSVFFRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSK 700 Query: 701 TASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALI 760 A+ M+L DD+FS I+ AVEEG+ I+ N+K F+R+ +S+++ + I L+ P L Sbjct: 701 EAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLN 760 Query: 761 PVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAAT 820 +Q+LW+N++ DG PA +LG P D D +PPR+ ++ ++S L + L + + T Sbjct: 761 AMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSAAIIISGT 820 Query: 821 VGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIE 880 + F+ KE D +P TM + V + Sbjct: 821 L-----------------------FIFWKEMPEDRA-------STPRTTTMTFTCFVFFD 850 Query: 881 MCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWL 940 + NAL S+ + + + N + S+ S+ ++Y+ PL +FQ L L Sbjct: 851 LFNALTCRSQTKLIFEIGFLRNHMFLYSVLGSILGQLAVIYIPPLQRVFQTENLGALDLL 910 Query: 941 MVLKISLPVILMDETLKFVARNYLEPGKECVQP 973 + ++ V ++ E LK + P + + P Sbjct: 911 FLTGLASSVFILSELLKLCEKYCCSPKRVQMHP 943 >gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] Length = 1035 Score = 344 bits (882), Expect = 3e-94 Identities = 290/1024 (28%), Positives = 468/1024 (45%), Gaps = 119/1024 (11%) Query: 3 NAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLV 62 N H +V E+ + + + GLS +L R G N L G Q L Sbjct: 53 NDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQ 112 Query: 63 RILLLAACISFVLAWFEEGEETITAFVEPFV---ILLILVANAIVGVWQERNAENAIEAL 119 ++ +AA I + + E +T ++ ++ ++V G +QE + N I + Sbjct: 113 CLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASF 172 Query: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVI 161 K P+ V R K +I A +V GD+VE+ G ++ S+ Sbjct: 173 KNLVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGCKVDNSSLT 230 Query: 162 KHTDP-VPDPRAVNQ---DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQ 217 ++P P ++ + +N+ F T G G+VV TG T IG+I E Sbjct: 231 GESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASGVEN 290 Query: 218 ERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAV 277 E+TP+ +++ F + ++ + L +I+ + G +++R +++ +A+ V Sbjct: 291 EKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MAIVV 340 Query: 278 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 337 A +PEGL A +T CL+L +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M+V Sbjct: 341 AYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVS 400 Query: 338 RMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 397 ++ + + + ++ +G T+ E + L + LCN +A Sbjct: 401 HLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALCRVLTLCNRAA 443 Query: 398 LDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 454 + K +G+A+ETAL LK S++ NA + K Sbjct: 444 FKSGQDAVPVPKRIVIGDASETAL-------------LK-FSELTLGNAMG--YRDRFPK 487 Query: 455 EFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 514 + F+ K T P R + +KGAPE V++RC+ I + ++P+ + Sbjct: 488 VCEIPFNSTNKFQLSIHTLEDP-RDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWR 546 Query: 515 QKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 573 + + G G L L ++ ++ NF + L F G V M+D Sbjct: 547 EAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAFDVEAMNF--PSSGLCFAGLVSMID 604 Query: 574 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----EDVTSK------ 623 PPR V +V CR AGIRVIM+TGD+ TA AI +GI + ED+ ++ Sbjct: 605 PPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVD 664 Query: 624 ----------AFTGREFDELNPSAQRDACLN--ARCFARVEPSHKSKIVEFLQSFDEITA 671 G + +++PS +A FAR P K IVE Q I A Sbjct: 665 QVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVA 724 Query: 672 MTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK 730 +TGDGVND+PALKKA+IG+AMG +G+ AK A++M+L DDNF++IV VE+GR I++N+K Sbjct: 725 VTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLK 784 Query: 731 QFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMN 790 + I Y ++ N+ E+ + + P L + +L++ L TD P+ +L + + DIM+ Sbjct: 785 KSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMH 844 Query: 791 KPPRNPK------EPLISGWLFFRYLAIGCYVGAA---TVGAAAWWFIAADGGPRVSFYQ 841 PRNPK EPL + + +F+ AI + G T A WF G R + Sbjct: 845 LRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWE- 902 Query: 842 LSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSV-LVTIEMCNALNSL---SENQSLLRM 897 H LQ D D G + + Y +V ++IE+C + L + S + Sbjct: 903 -DHHLQ---DLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQ 958 Query: 898 PPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLK 957 + N LV +I + + + Y +P IF P+ WL+ L + + + DE K Sbjct: 959 GFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRK 1018 Query: 958 FVAR 961 R Sbjct: 1019 LGVR 1022 >gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens] Length = 1029 Score = 343 bits (881), Expect = 4e-94 Identities = 290/1026 (28%), Positives = 473/1026 (46%), Gaps = 126/1026 (12%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELP----AEEGKTLLELVIEQFEDL 60 H T+EE+ + V+ + G S ++ K++ R G N + E + + F L Sbjct: 52 HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111 Query: 61 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 L +L + +F E E T V+ ++++ +QE + +E+ K Sbjct: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVIK 162 P+ V R K +I +++V GD+VEI G ++ S+ Sbjct: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTG 228 Query: 163 HTDPV---PDPRAVNQ-DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 218 ++P PD N + +N+ F TN G A G+V+ATG +T +G+I Sbjct: 229 ESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVG 288 Query: 219 RTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278 +TP+ +++ F ++ V + + + +++ + G W+ I+ + + VA Sbjct: 289 QTPIAAEIEHFIHLITVVAVFLGVTFFALSL------LLGYGWLEAIIFL----IGIIVA 338 Query: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338 +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V Sbjct: 339 NVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAH 398 Query: 339 M-FILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 397 M F + E DT TG T+ D LA I LCN + Sbjct: 399 MWFDMTVYEADTTEEQ----TGKTFTKSS--------------DTWFMLARIAGLCNRAD 440 Query: 398 LDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 454 N+ K G+A+E+AL L IE++ + + +++ K Sbjct: 441 FKANQEILPIAKRATTGDASESAL----------------LKFIEQSYSSVAEMREKNPK 484 Query: 455 EFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 513 + F+ K MS++ + S+T + + +KGAPE +++ C+ + + M + Sbjct: 485 VAEIPFNSTNKYQMSIHLREDS-SQTHV--LMMKGAPERILEFCSTFLLNGQEYSMNDEM 541 Query: 514 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD 573 K+ + E G + + + + D NF NL FVG + M+D Sbjct: 542 KEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDEINFPM--DNLCFVGLISMID 599 Query: 574 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT------- 626 PPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + + Sbjct: 600 PPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVAARLKIPIS 659 Query: 627 -------------GREFDELNPSAQRDACLNAR---CFARVEPSHKSKIVEFLQSFDEIT 670 G E ++ S Q D L FAR P K IVE Q + Sbjct: 660 KVDASAAKAIVVHGAELKDIQ-SKQLDQILQNHPEIVFARTSPQQKLIIVEGCQRLGAVV 718 Query: 671 AMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNM 729 A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEGR I++N+ Sbjct: 719 AVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNL 778 Query: 730 KQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM 789 K+ I Y ++SN+ E+ + LG P L + +L ++L TD +PA +L + + DIM Sbjct: 779 KKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIM 838 Query: 790 NKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPR------VSFYQ 841 + PRNPK + L++ L Y IG A G ++ I A+ G R + + Sbjct: 839 KRLPRNPKTDNLVNHRLIGMAYGQIGMI--QALAGFFTYFVILAENGFRPVDLLGIRLHW 896 Query: 842 LSHFLQCKEDNP----DFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRM 897 +L ED+ +E F T +V ++ + + S + SL + Sbjct: 897 EDKYLNDLEDSYGQQWTYEQRKVVEFTC---QTAFFVTIVVVQWADLIISKTRRNSLFQQ 953 Query: 898 PPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLK 957 + + G + ++ FL Y + + ++ PL +T WL + S+ + + DE K Sbjct: 954 GMRNKVLIFGILEETLLAAFL-SYTPGMDVALRMYPLKITWWLCAIPYSILIFVYDEIRK 1012 Query: 958 FVARNY 963 + R + Sbjct: 1013 LLIRQH 1018 >gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] Length = 1020 Score = 341 bits (874), Expect = 2e-93 Identities = 284/1022 (27%), Positives = 479/1022 (46%), Gaps = 117/1022 (11%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 H +++E+ + V+ S GL+ ++ + + R G N L P ++ + F + Sbjct: 42 HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 100 Query: 64 ILLLAACISFVLAWFE---EGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120 +L + A + F+ + E E + V+ +++ +QE + +++ K Sbjct: 101 LLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFK 160 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVIK 162 P+ V R+ K +I A+++V GD+VE+ G ++ S+ Sbjct: 161 NMVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTG 218 Query: 163 HTDP-VPDPRAVNQ---DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 218 ++P P ++ + +N+ F TN G A G+V+ATG T +G+I E Sbjct: 219 ESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVG 278 Query: 219 RTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278 RTP+ +++ F + ++ V + ++ +++++ + G SW+ I+ + + VA Sbjct: 279 RTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IGIIVA 328 Query: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338 +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V Sbjct: 329 NVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAH 388 Query: 339 MFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 397 M+ +++ E DT +G+T+ DK + L +A +C A Sbjct: 389 MWFDNQIHEADTTEDQ----SGATF---------DK--RSPTWTALSRIAGLCNRAVFKA 433 Query: 398 LDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFT 457 N + + G+A+E+AL +E +C SV K + Sbjct: 434 GQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRNPKV 475 Query: 458 LEF---SRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVK 514 E S ++ +S++ + P + +KGAPE ++DRC+ I V ++P+ ++ Sbjct: 476 AEIPFNSTNKYQLSIHEREDSPQS---HVLVMKGAPERILDRCSTILVQGKEIPLDKEMQ 532 Query: 515 QKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN-LTFVGCVGMLD 573 + E G + R L + P + + + + + T L FVG + M+D Sbjct: 533 DAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMID 590 Query: 574 PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK--AFTGREFD 631 PPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + A Sbjct: 591 PPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMS 650 Query: 632 ELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVEFLQSFDEITA 671 ++NP S Q D L FAR P K IVE Q I A Sbjct: 651 QVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVA 710 Query: 672 MTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK 730 +TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV VEEGR I++N+K Sbjct: 711 VTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLK 770 Query: 731 QFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMN 790 + I Y ++SN+ E+ L P L V +L ++L TD +PA +L + + DIM Sbjct: 771 KSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMK 830 Query: 791 KPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGG---PRVSFYQLSHF 845 + PRN + + L++ L Y IG A G ++ I A+ G R+ +L Sbjct: 831 RQPRNSQTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENGFLPSRLLGIRLDWD 888 Query: 846 LQCKEDNPDFEGVDCAIFESPYP----MTMALSVLVTIEMCNALNSLSENQSLLRMPPWE 901 + D D G + + T + +V ++ + + + S+ + + Sbjct: 889 DRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQ-GMK 947 Query: 902 NIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVAR 961 N L+ + +L + Y + + ++ PL VT W SL + + DE K + R Sbjct: 948 NKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILR 1007 Query: 962 NY 963 Y Sbjct: 1008 RY 1009 >gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] Length = 1013 Score = 333 bits (855), Expect = 4e-91 Identities = 256/854 (29%), Positives = 422/854 (49%), Gaps = 118/854 (13%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 H +VEEV + + GL+ + +++ R G N L P ++ + F + Sbjct: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 92 Query: 64 ILLLAACISFVLAWFEEGEETITAFVEPF---VILLILVANAIVGVWQERNAENAIEALK 120 +L + A + F+ + G E + + V+ +++ +QE + +E+ K Sbjct: 93 LLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFK 152 Query: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVIK 162 P+ V R+ K ++ A+++V GD+VEI G ++ S+ Sbjct: 153 NMVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTG 210 Query: 163 HTDPV---PDPRAVNQ-DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 218 ++P PD N + +N+ F TN G A GVVVATG T +G+I E Sbjct: 211 ESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVG 270 Query: 219 RTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278 +TP+ +++ F + ++ V + ++ +I+++ + G +W+ I+ + + VA Sbjct: 271 KTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IGIIVA 320 Query: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338 +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V Sbjct: 321 NVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAH 380 Query: 339 MFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 397 M+ +++ E DT +G+++ DK + H + V L+ I LCN + Sbjct: 381 MWFDNQIHEADTTEDQ----SGTSF---------DK--SSHTW---VALSHIAGLCNRAV 422 Query: 398 LDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 454 + K G+A+E+AL L IE ++ ++++ KK Sbjct: 423 FKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLMRERNKK 466 Query: 455 EFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 513 + F+ K +S++ T + + + +KGAPE ++DRC+ I + + P+ + Sbjct: 467 VAEIPFNSTNKYQLSIHETEDPNDNRYL--LVMKGAPERILDRCSTILLQGKEQPLDEEM 524 Query: 514 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYET-NLTFVGCVGML 572 K+ + E G + R L + P + + + + T NL FVG + M+ Sbjct: 525 KEAFQNAYLELGGLGE--RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMI 582 Query: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----EDVTS------ 622 DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + ED+ + Sbjct: 583 DPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPV 642 Query: 623 ------------------KAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQ 664 K FT + DE+ + FAR P K IVE Q Sbjct: 643 SQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIV------FARTSPQQKLIIVEGCQ 696 Query: 665 SFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGR 723 I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV VEEGR Sbjct: 697 RQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGR 756 Query: 724 AIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNP 783 I++N+K+ I Y ++SN+ E+ L P L + +L ++L TD +PA +L + Sbjct: 757 LIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEA 816 Query: 784 PDLDIMNKPPRNPK 797 + DIM + PRNP+ Sbjct: 817 AESDIMKRQPRNPR 830 >gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens] Length = 1023 Score = 330 bits (845), Expect = 5e-90 Identities = 288/1031 (27%), Positives = 468/1031 (45%), Gaps = 138/1031 (13%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 H +++E+ +G + S GL+ + ++ R G N L P ++ + F + Sbjct: 44 HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSM- 102 Query: 64 ILLLAACISF----VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEAL 119 +L + A + F + A EE + ++ V+ +++ +QE + +E+ Sbjct: 103 LLWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESF 161 Query: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVI 161 K P+ V R K I A+++V GD+VE+ G ++ S+ Sbjct: 162 KNMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLT 219 Query: 162 KHTDP-VPDPRAVNQ---DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQ 217 ++P P N+ + +N+ F TN G A G+VV TG T +G+I E Sbjct: 220 GESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEG 279 Query: 218 ERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAV 277 +TP+ +++ F ++ V + ++ +I+++ + +W+ I+ + + V Sbjct: 280 GQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL----IGIIV 329 Query: 278 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 337 A +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V Sbjct: 330 ANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVA 389 Query: 338 RMFILDRV-EGDTCSLNE---FTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 M+ +++ E DT F T +T+ + L+ I LC Sbjct: 390 HMWFDNQIHEADTTENQSGVSFDKTSATW---------------------LALSRIAGLC 428 Query: 394 NDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSV--I 448 N + N+ K G+A+E+AL +E C SV + Sbjct: 429 NRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVKEM 470 Query: 449 KQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKV 507 ++ K + F+ K +S++ PN + + +KGAPE ++DRC+ I + + Sbjct: 471 RERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL--LVMKGAPERILDRCSSILLHGKEQ 528 Query: 508 PMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFV 566 P+ +K + E G G L L D D NF NL FV Sbjct: 529 PLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPI--DNLCFV 586 Query: 567 GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK--A 624 G + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + A Sbjct: 587 GLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 646 Query: 625 FTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVEFLQ 664 ++NP S Q D L FAR P K IVE Q Sbjct: 647 RLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQ 706 Query: 665 SFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGR 723 I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV VEEGR Sbjct: 707 RQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGR 766 Query: 724 AIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNP 783 I++N+K+ I Y ++SN+ E+ + P L V +L ++L TD +PA +L + Sbjct: 767 LIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQ 826 Query: 784 PDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQ 841 + DIM + PRNPK + L++ L Y IG A G ++ I A+ G + Sbjct: 827 AESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENG-----FL 879 Query: 842 LSHFLQCKEDNPD--FEGVDCAIFES---------PYPMTMALSVLVTIEMCNALNSLSE 890 H L + D D V+ + + + A V + + L Sbjct: 880 PIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKT 939 Query: 891 NQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVI 950 ++ + +N L+ + +L + Y + + ++ PL T W SL + Sbjct: 940 RRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIF 999 Query: 951 LMDETLKFVAR 961 + DE K + R Sbjct: 1000 VYDEVRKLIIR 1010 >gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens] Length = 992 Score = 330 bits (845), Expect = 5e-90 Identities = 288/1031 (27%), Positives = 468/1031 (45%), Gaps = 138/1031 (13%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 H +++E+ +G + S GL+ + ++ R G N L P ++ + F + Sbjct: 13 HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSM- 71 Query: 64 ILLLAACISF----VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEAL 119 +L + A + F + A EE + ++ V+ +++ +QE + +E+ Sbjct: 72 LLWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESF 130 Query: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVI 161 K P+ V R K I A+++V GD+VE+ G ++ S+ Sbjct: 131 KNMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLT 188 Query: 162 KHTDP-VPDPRAVNQ---DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQ 217 ++P P N+ + +N+ F TN G A G+VV TG T +G+I E Sbjct: 189 GESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEG 248 Query: 218 ERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAV 277 +TP+ +++ F ++ V + ++ +I+++ + +W+ I+ + + V Sbjct: 249 GQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL----IGIIV 298 Query: 278 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 337 A +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V Sbjct: 299 ANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVA 358 Query: 338 RMFILDRV-EGDTCSLNE---FTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 M+ +++ E DT F T +T+ + L+ I LC Sbjct: 359 HMWFDNQIHEADTTENQSGVSFDKTSATW---------------------LALSRIAGLC 397 Query: 394 NDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSV--I 448 N + N+ K G+A+E+AL +E C SV + Sbjct: 398 NRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVKEM 439 Query: 449 KQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKV 507 ++ K + F+ K +S++ PN + + +KGAPE ++DRC+ I + + Sbjct: 440 RERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL--LVMKGAPERILDRCSSILLHGKEQ 497 Query: 508 PMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFV 566 P+ +K + E G G L L D D NF NL FV Sbjct: 498 PLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPI--DNLCFV 555 Query: 567 GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK--A 624 G + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + A Sbjct: 556 GLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 615 Query: 625 FTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVEFLQ 664 ++NP S Q D L FAR P K IVE Q Sbjct: 616 RLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQ 675 Query: 665 SFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGR 723 I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV VEEGR Sbjct: 676 RQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGR 735 Query: 724 AIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNP 783 I++N+K+ I Y ++SN+ E+ + P L V +L ++L TD +PA +L + Sbjct: 736 LIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQ 795 Query: 784 PDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQ 841 + DIM + PRNPK + L++ L Y IG A G ++ I A+ G + Sbjct: 796 AESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENG-----FL 848 Query: 842 LSHFLQCKEDNPD--FEGVDCAIFES---------PYPMTMALSVLVTIEMCNALNSLSE 890 H L + D D V+ + + + A V + + L Sbjct: 849 PIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKT 908 Query: 891 NQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVI 950 ++ + +N L+ + +L + Y + + ++ PL T W SL + Sbjct: 909 RRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIF 968 Query: 951 LMDETLKFVAR 961 + DE K + R Sbjct: 969 VYDEVRKLIIR 979 >gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] Length = 1023 Score = 330 bits (845), Expect = 5e-90 Identities = 288/1031 (27%), Positives = 468/1031 (45%), Gaps = 138/1031 (13%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 H +++E+ +G + S GL+ + ++ R G N L P ++ + F + Sbjct: 44 HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSM- 102 Query: 64 ILLLAACISF----VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEAL 119 +L + A + F + A EE + ++ V+ +++ +QE + +E+ Sbjct: 103 LLWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESF 161 Query: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVI 161 K P+ V R K I A+++V GD+VE+ G ++ S+ Sbjct: 162 KNMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLT 219 Query: 162 KHTDP-VPDPRAVNQ---DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQ 217 ++P P N+ + +N+ F TN G A G+VV TG T +G+I E Sbjct: 220 GESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEG 279 Query: 218 ERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAV 277 +TP+ +++ F ++ V + ++ +I+++ + +W+ I+ + + V Sbjct: 280 GQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL----IGIIV 329 Query: 278 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 337 A +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V Sbjct: 330 ANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVA 389 Query: 338 RMFILDRV-EGDTCSLNE---FTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393 M+ +++ E DT F T +T+ + L+ I LC Sbjct: 390 HMWFDNQIHEADTTENQSGVSFDKTSATW---------------------LALSRIAGLC 428 Query: 394 NDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSV--I 448 N + N+ K G+A+E+AL +E C SV + Sbjct: 429 NRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVKEM 470 Query: 449 KQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKV 507 ++ K + F+ K +S++ PN + + +KGAPE ++DRC+ I + + Sbjct: 471 RERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL--LVMKGAPERILDRCSSILLHGKEQ 528 Query: 508 PMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFV 566 P+ +K + E G G L L D D NF NL FV Sbjct: 529 PLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPI--DNLCFV 586 Query: 567 GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK--A 624 G + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + + A Sbjct: 587 GLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 646 Query: 625 FTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVEFLQ 664 ++NP S Q D L FAR P K IVE Q Sbjct: 647 RLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQ 706 Query: 665 SFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGR 723 I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV VEEGR Sbjct: 707 RQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGR 766 Query: 724 AIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNP 783 I++N+K+ I Y ++SN+ E+ + P L V +L ++L TD +PA +L + Sbjct: 767 LIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQ 826 Query: 784 PDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQ 841 + DIM + PRNPK + L++ L Y IG A G ++ I A+ G + Sbjct: 827 AESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENG-----FL 879 Query: 842 LSHFLQCKEDNPD--FEGVDCAIFES---------PYPMTMALSVLVTIEMCNALNSLSE 890 H L + D D V+ + + + A V + + L Sbjct: 880 PIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKT 939 Query: 891 NQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVI 950 ++ + +N L+ + +L + Y + + ++ PL T W SL + Sbjct: 940 RRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIF 999 Query: 951 LMDETLKFVAR 961 + DE K + R Sbjct: 1000 VYDEVRKLIIR 1010 >gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] Length = 1039 Score = 308 bits (790), Expect = 1e-83 Identities = 249/868 (28%), Positives = 410/868 (47%), Gaps = 112/868 (12%) Query: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFE--DLL 61 H + E+ +G + GLS + +L R G N L P ++ +++ + + +L Sbjct: 59 HKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSIL 118 Query: 62 VRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKE 121 + + I++ + + + ++ V+ L+++ I +QE + N + + + Sbjct: 119 LWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNK 178 Query: 122 YEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVIKH 163 P+ V R K I ++ +V GDIVE+ G ++ S+ Sbjct: 179 MIPQQALVIRDSEKKT--IPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGE 236 Query: 164 TDPVPDPRAVNQDK----KNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQER 219 ++P P + KN+ F T G G+V+ TG T IG I E+ Sbjct: 237 SEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEK 296 Query: 220 TPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAA 279 TP+ +++ F ++ V I I +II + + ++ G I VA Sbjct: 297 TPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGII----------VAN 346 Query: 280 IPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRM 339 +PEGL A +T L+L +RMAKKN +V++L +VETLG TS+ICSDKTGTLT N+M+V + Sbjct: 347 VPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHL 406 Query: 340 FILDRV----EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCND 395 + +++ + S F + T+A L+ I LCN Sbjct: 407 WFDNQIFVADTSEDHSNQVFDQSSRTWA---------------------SLSKIITLCNR 445 Query: 396 SALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLM 452 + + K +G+A+ETAL E + L + +I + N Sbjct: 446 AEFKPGQENVPIMKKAVIGDASETALLKFSEVI------LGDVMEIRKRN---------- 489 Query: 453 KKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTS 511 +K + F+ K +S++ + + + M +KGAPE ++++C+ I + + P+ Sbjct: 490 RKVAEIPFNSTNKFQLSIHEMDDPHGKRFL--MVMKGAPERILEKCSTIMINGEEHPLDK 547 Query: 512 GVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVG 570 + + E G G L L + D+ NF +NL FVG + Sbjct: 548 STAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPT--SNLCFVGLLS 605 Query: 571 MLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDE------------ 618 M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + Sbjct: 606 MIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNI 665 Query: 619 --------DVTSKAFTGREFDELNPSAQRDACLNAR--CFARVEPSHKSKIVEFLQSFDE 668 D + TG E +++ + N + FAR P K IVE Q D Sbjct: 666 AVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDA 725 Query: 669 ITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYN 727 + A+TGDGVND+PALKKA+IGIAMG +G+ AK A++MVL DDNF++IV VEEGR I++ Sbjct: 726 VVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFD 785 Query: 728 NMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLD 787 N+K+ I Y ++ N+ E+ + +G P + + +L+++L TD +P+ AL + + D Sbjct: 786 NLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESD 845 Query: 788 IMNKPPRNP-KEPLISGWL-FFRYLAIG 813 IMN+ PR+ K+ L++ L + YL IG Sbjct: 846 IMNRKPRHKNKDRLVNQPLAVYSYLHIG 873 >gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens] Length = 1198 Score = 276 bits (705), Expect = 9e-74 Identities = 256/890 (28%), Positives = 401/890 (45%), Gaps = 151/890 (16%) Query: 29 VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF---------- 78 ++K K+ +G N +P ++ KT L+LV E +D+ + IL +AA IS L+++ Sbjct: 75 LEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGC 134 Query: 79 -------EEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYR 131 E+ E ++E ILL ++ +V + + + E L+ + K Sbjct: 135 ATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 194 Query: 132 QDRKSVQRIKAKDIVPGDIVEIA-GESVSV----IKHTDPVPDPRAV---------NQDK 177 V +I +IV GDI ++ G+ + I+ D D ++ + DK Sbjct: 195 VRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDK 254 Query: 178 KNMLFSGTNIAAGKAMGVVVATGVNTEIG--------------------KIRDEMVATE- 216 ML SGT++ G +V A GVN++ G K +D A E Sbjct: 255 DPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEM 314 Query: 217 ---------------------QERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHF 252 +E++ LQ KL + Q+ K V+S I + + ++ Sbjct: 315 QPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVD 374 Query: 253 NDPVHGGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNA 304 V+ W ++ + +F I V + V A+PEGLP +T LA ++M K N Sbjct: 375 TFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNN 434 Query: 305 IVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAP 364 +VR L + ET+G + ICSDKTGTLTTN+M+V + ++ Sbjct: 435 LVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV----------------------- 471 Query: 365 IGEVHKDDKP----VNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTC 420 G+VH + P +N + L+ I + L + + +VG TE L Sbjct: 472 -GDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLG 530 Query: 421 LVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRT 479 V + K + + + ++ + K +T F+ RKSMS V P++ R Sbjct: 531 FVLDL-----------KQDYEPVRSQMPEEKLYKVYT--FNSVRKSMSTVIKLPDESFR- 576 Query: 480 SMSKMFVKGAPEGVIDRCTHIR--VGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALA 537 M+ KGA E V+ +C I G +V + + VI D LR + +A Sbjct: 577 ----MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMAC--DGLRTICVA 630 Query: 538 THDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMIT 597 D P E D+ N I E LT + VG+ DP R EV +++ C++AGI V M+T Sbjct: 631 YRDFPSSPEPDW--DNENDILNE--LTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVT 686 Query: 598 GDNKGTAVAICRRIGIFGQDED---VTSKAFTGR---EFDELNPSAQRDACLNARCFARV 651 GDN TA AI + GI ED + K F R E E+ R AR Sbjct: 687 GDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARS 746 Query: 652 EPSHKSKIVEFLQSFD-----EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEM 705 P+ K +V+ + ++ A+TGDG ND PALKKA++G AMG +GT VAK AS++ Sbjct: 747 SPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDI 806 Query: 706 VLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLL 765 +L DDNFS+IV AV GR +Y+++ +F+++ ++ NV V+ F A + L VQ+L Sbjct: 807 ILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQML 866 Query: 766 WVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCY 815 WVNL+ D + AL PP ++ + P +PLIS + L Y Sbjct: 867 WVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 916 >gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sapiens] Length = 1170 Score = 271 bits (692), Expect = 3e-72 Identities = 287/1095 (26%), Positives = 467/1095 (42%), Gaps = 194/1095 (17%) Query: 3 NAHTKTVEEVLGHFGVNESTGLSLE--QVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 N H V+ + + GLS ++K ++ +G N +P ++ KT LELV E +D+ Sbjct: 45 NVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDV 104 Query: 61 LVRILLLAACISFVLAWF-----------------EEGEETITAFVEPFVILLILVANAI 103 + IL +AA IS VL+++ E+ E ++E IL ++ + Sbjct: 105 TLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVL 164 Query: 104 VGVWQERNAENAIEALK-EYEPEMGKVYRQDRKSVQ------------RIKAKDIVPGDI 150 V + + + E L+ E E ++ + +Q ++K D++P D Sbjct: 165 VTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG 224 Query: 151 VEIAGESVSVIKHT-DPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATG--------- 200 + I G + + + + D + DK ML SGT++ G VV A G Sbjct: 225 ILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIL 284 Query: 201 -----------------------------------------VNTEIG-----KIRDEMVA 214 +N++ G K + + Sbjct: 285 TLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKV 344 Query: 215 TEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVHGGSW--------IR 263 ++E++ LQ KL Q+ K ++S + + + I+ N ++ W I+ Sbjct: 345 PKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQ 404 Query: 264 GAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICS 323 + +F I + + V A+PEGLP +T LA ++M K N +VR L + ET+G + ICS Sbjct: 405 YFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICS 464 Query: 324 DKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNC----HQ 379 DKTGTLT N+M+V + +I G +H P Sbjct: 465 DKTGTLTMNRMTVVQAYI------------------------GGIHYRQIPSPDVFLPKV 500 Query: 380 YDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIE 439 D +V +I + L + G+ +VG TE AL V T+LK + Sbjct: 501 LDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAV 553 Query: 440 RANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKMFVKGAPEGVIDRCT 498 R N V ++ + K +T F+ RKSMS V PN R M+ KGA E ++ +C Sbjct: 554 R----NEVPEEKLYKVYT--FNSVRKSMSTVIRNPNGGFR-----MYSKGASEIILRKCN 602 Query: 499 HI--RVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANF 556 I R G VP + + ++ + E D LR + +A D D+ N Sbjct: 603 RILDRKGEA-VPFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSW---DNENE 657 Query: 557 IKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQ 616 I T LT + VG+ DP R EV ++ C+QAGI V M+TGDN TA AI + GI Sbjct: 658 IL--TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTP 715 Query: 617 DEDVTSKAFTGREFDELNPSAQRDA--------CLNARCFARVEPSHKSKIVEFL----- 663 +D G+EF+ L + + + R AR P+ K +V+ + Sbjct: 716 GDDFL--CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTV 773 Query: 664 QSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEG 722 ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV G Sbjct: 774 GEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWG 833 Query: 723 RAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFN 782 R +Y+++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D + AL Sbjct: 834 RNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATE 893 Query: 783 PPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQL 842 PP ++ + P +PLIS + L Y FI G + F+ + Sbjct: 894 PPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVI-------FILVFAGEK--FFDI 944 Query: 843 SHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLS-ENQSLLRMPPWE 901 + +P + T+ + V +++ N +NS + + + Sbjct: 945 DSGRKAPLHSPPSQ-----------HYTIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYR 993 Query: 902 NIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVAR 961 NI + + I+ P F T L+++QWL L I + +L + + + Sbjct: 994 NIIFCSVVLGTFICQIFIVEFGGKP--FSCTSLSLSQWLWCLFIGIGELLWGQFISAIPT 1051 Query: 962 NYLEPGKECVQPATK 976 L+ KE TK Sbjct: 1052 RSLKFLKEAGHGTTK 1066 >gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sapiens] Length = 1205 Score = 271 bits (692), Expect = 3e-72 Identities = 287/1095 (26%), Positives = 467/1095 (42%), Gaps = 194/1095 (17%) Query: 3 NAHTKTVEEVLGHFGVNESTGLSLE--QVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 N H V+ + + GLS ++K ++ +G N +P ++ KT LELV E +D+ Sbjct: 45 NVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDV 104 Query: 61 LVRILLLAACISFVLAWF-----------------EEGEETITAFVEPFVILLILVANAI 103 + IL +AA IS VL+++ E+ E ++E IL ++ + Sbjct: 105 TLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVL 164 Query: 104 VGVWQERNAENAIEALK-EYEPEMGKVYRQDRKSVQ------------RIKAKDIVPGDI 150 V + + + E L+ E E ++ + +Q ++K D++P D Sbjct: 165 VTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG 224 Query: 151 VEIAGESVSVIKHT-DPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATG--------- 200 + I G + + + + D + DK ML SGT++ G VV A G Sbjct: 225 ILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIL 284 Query: 201 -----------------------------------------VNTEIG-----KIRDEMVA 214 +N++ G K + + Sbjct: 285 TLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKV 344 Query: 215 TEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVHGGSW--------IR 263 ++E++ LQ KL Q+ K ++S + + + I+ N ++ W I+ Sbjct: 345 PKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQ 404 Query: 264 GAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICS 323 + +F I + + V A+PEGLP +T LA ++M K N +VR L + ET+G + ICS Sbjct: 405 YFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICS 464 Query: 324 DKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNC----HQ 379 DKTGTLT N+M+V + +I G +H P Sbjct: 465 DKTGTLTMNRMTVVQAYI------------------------GGIHYRQIPSPDVFLPKV 500 Query: 380 YDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIE 439 D +V +I + L + G+ +VG TE AL V T+LK + Sbjct: 501 LDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAV 553 Query: 440 RANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKMFVKGAPEGVIDRCT 498 R N V ++ + K +T F+ RKSMS V PN R M+ KGA E ++ +C Sbjct: 554 R----NEVPEEKLYKVYT--FNSVRKSMSTVIRNPNGGFR-----MYSKGASEIILRKCN 602 Query: 499 HI--RVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANF 556 I R G VP + + ++ + E D LR + +A D D+ N Sbjct: 603 RILDRKGEA-VPFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSW---DNENE 657 Query: 557 IKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQ 616 I T LT + VG+ DP R EV ++ C+QAGI V M+TGDN TA AI + GI Sbjct: 658 IL--TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTP 715 Query: 617 DEDVTSKAFTGREFDELNPSAQRDA--------CLNARCFARVEPSHKSKIVEFL----- 663 +D G+EF+ L + + + R AR P+ K +V+ + Sbjct: 716 GDDFL--CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTV 773 Query: 664 QSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEG 722 ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV G Sbjct: 774 GEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWG 833 Query: 723 RAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFN 782 R +Y+++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D + AL Sbjct: 834 RNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATE 893 Query: 783 PPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQL 842 PP ++ + P +PLIS + L Y FI G + F+ + Sbjct: 894 PPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVI-------FILVFAGEK--FFDI 944 Query: 843 SHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLS-ENQSLLRMPPWE 901 + +P + T+ + V +++ N +NS + + + Sbjct: 945 DSGRKAPLHSPPSQ-----------HYTIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYR 993 Query: 902 NIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVAR 961 NI + + I+ P F T L+++QWL L I + +L + + + Sbjct: 994 NIIFCSVVLGTFICQIFIVEFGGKP--FSCTSLSLSQWLWCLFIGIGELLWGQFISAIPT 1051 Query: 962 NYLEPGKECVQPATK 976 L+ KE TK Sbjct: 1052 RSLKFLKEAGHGTTK 1066 >gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sapiens] Length = 1220 Score = 257 bits (656), Expect = 4e-68 Identities = 252/902 (27%), Positives = 397/902 (44%), Gaps = 159/902 (17%) Query: 29 VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF----EEGE-- 82 ++K ++ +G N +P ++ KT L+LV E +D+ + IL +AA +S L+++ EE E Sbjct: 78 LEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEAC 137 Query: 83 -----------ETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGK--V 129 E ++E ILL ++ +V + + + E L+ + K V Sbjct: 138 GNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 197 Query: 130 YRQDRK-----------SVQRIKAKDIVPGDIVEIAGESVSVIKHT-DPVPDPRAVNQDK 177 R + + ++K D++P D V I + + + + D + DK Sbjct: 198 IRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADK 257 Query: 178 KNMLFSGTNIAAGK------AMGVVVATGVNTEI-------------------------- 205 ML SGT++ G A+GV TG+ + Sbjct: 258 DPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQ 317 Query: 206 --GKIRDEMVATE------------------------QERTPLQQKLDEFGEQLSK---V 236 K +D VA E +E++ LQ KL + Q+ K V Sbjct: 318 TKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLV 377 Query: 237 ISLICIAVWIINIGHFNDPVHGGSWIRGA--------IYYFKIAVALAVAAIPEGLPAVI 288 +S I + + ++ V G +W+ + +F I V + V A+PEGLP + Sbjct: 378 MSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAV 437 Query: 289 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGD 348 T LA ++M K N +VR L + ET+G + ICSDKTGTLTTN+M+V + ++ GD Sbjct: 438 TISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYL-----GD 492 Query: 349 TCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYE 408 T E + I D LV +I + L + + Sbjct: 493 T-HYKEIPAPSALTPKI--------------LDLLVHAISINSAYTTKILPPEKEGALPR 537 Query: 409 KVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS 468 +VG TE AL V + K + + + + K +T F+ RKSMS Sbjct: 538 QVGNKTECALLGFVLDL-----------KRDFQPVREQIPEDKLYKVYT--FNSVRKSMS 584 Query: 469 -VYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHI--RVGSTKVPMTSGVKQKIMSVIREWG 525 V P+ R +F KGA E ++ +CT+I G + + +I Sbjct: 585 TVIRMPDGGFR-----LFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMA 639 Query: 526 SGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKL 585 D LR + +A D +E D N + +LT + VG+ DP R EV +++ Sbjct: 640 C--DGLRTICIAYRDFSAGQEP----DWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRK 693 Query: 586 CRQAGIRVIMITGDNKGTAVAICRRIGIFGQDED---VTSKAFTGR---EFDELNPSAQR 639 C++AGI V M+TGDN TA AI + GI ED + K F R E E+ Sbjct: 694 CQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLD 753 Query: 640 DACLNARCFARVEPSHKSKIVEFLQSFD-----EITAMTGDGVNDAPALKKAEIGIAMG- 693 R AR P+ K +V+ + ++ A+TGDG ND PALKKA++G AMG Sbjct: 754 KVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGI 813 Query: 694 SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL 753 +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++ NV V+ F A + Sbjct: 814 AGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACI 873 Query: 754 GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG 813 L VQ+LWVNL+ D + AL PP ++ + P +PLIS + L Sbjct: 874 TQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHA 933 Query: 814 CY 815 Y Sbjct: 934 VY 935 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.135 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,346,801 Number of Sequences: 37866 Number of extensions: 1632956 Number of successful extensions: 4094 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 59 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 3799 Number of HSP's gapped (non-prelim): 140 length of query: 1015 length of database: 18,247,518 effective HSP length: 112 effective length of query: 903 effective length of database: 14,006,526 effective search space: 12647892978 effective search space used: 12647892978 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.