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Search of human proteins with 205360949
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205360949 fatty acid 2-hydroxylase [Homo sapiens]
(372 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205360949 fatty acid 2-hydroxylase [Homo sapiens] 790 0.0
gi|83921614 cytochrome b5 outer mitochondrial membrane precursor... 57 3e-08
gi|41281768 cytochrome b-5 isoform 1 [Homo sapiens] 55 8e-08
gi|4503183 cytochrome b-5 isoform 2 [Homo sapiens] 54 2e-07
gi|214831730 fatty acid desaturase 1 [Homo sapiens] 45 8e-05
gi|74099704 sulfite oxidase [Homo sapiens] 44 3e-04
gi|74099702 sulfite oxidase [Homo sapiens] 44 3e-04
gi|74099694 sulfite oxidase [Homo sapiens] 44 3e-04
gi|13375616 fatty acid desaturase 3 [Homo sapiens] 42 0.001
gi|84875541 cytochrome b5 reductase 4 [Homo sapiens] 40 0.003
gi|4758334 fatty acid desaturase 2 [Homo sapiens] 34 0.19
gi|40255272 xin actin-binding repeat containing 1 [Homo sapiens] 33 0.54
gi|52627217 olfactory receptor, family 2, subfamily AT, member 4... 32 1.2
gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate... 31 1.6
gi|40255060 cytochrome b5 domain containing 1 [Homo sapiens] 31 2.0
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 30 3.5
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 30 3.5
gi|46391075 hypothetical protein LOC79949 [Homo sapiens] 30 4.6
gi|239751570 PREDICTED: hypothetical protein XP_002347902 [Homo ... 29 6.0
gi|239746082 PREDICTED: hypothetical protein XP_002343651 [Homo ... 29 6.0
gi|41393547 neuroblastoma-amplified protein [Homo sapiens] 29 7.8
gi|62865628 sterol-C4-methyl oxidase-like isoform 2 [Homo sapiens] 29 7.8
gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo sapiens] 29 7.8
>gi|205360949 fatty acid 2-hydroxylase [Homo sapiens]
Length = 372
Score = 790 bits (2041), Expect = 0.0
Identities = 372/372 (100%), Positives = 372/372 (100%)
Query: 1 MAPAPPPAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISA 60
MAPAPPPAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISA
Sbjct: 1 MAPAPPPAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISA 60
Query: 61 DLDGPPHRHSANARRWLEQYYVGELRGEQQGSMENEPVALEETQKTDPAMEPRFKVVDWD 120
DLDGPPHRHSANARRWLEQYYVGELRGEQQGSMENEPVALEETQKTDPAMEPRFKVVDWD
Sbjct: 61 DLDGPPHRHSANARRWLEQYYVGELRGEQQGSMENEPVALEETQKTDPAMEPRFKVVDWD 120
Query: 121 KDLVDWRKPLLWQVGHLGEKYDEWVHQPVTRPIRLFHSDLIEGLSKTVWYSVPIIWVPLV 180
KDLVDWRKPLLWQVGHLGEKYDEWVHQPVTRPIRLFHSDLIEGLSKTVWYSVPIIWVPLV
Sbjct: 121 KDLVDWRKPLLWQVGHLGEKYDEWVHQPVTRPIRLFHSDLIEGLSKTVWYSVPIIWVPLV 180
Query: 181 LYLSWSYYRTFAQGNVRLFTSFTTEYTVAVPKSMFPGLFMLGTFLWSLIEYLIHRFLFHM 240
LYLSWSYYRTFAQGNVRLFTSFTTEYTVAVPKSMFPGLFMLGTFLWSLIEYLIHRFLFHM
Sbjct: 181 LYLSWSYYRTFAQGNVRLFTSFTTEYTVAVPKSMFPGLFMLGTFLWSLIEYLIHRFLFHM 240
Query: 241 KPPSDSYYLIMLHFVMHGQHHKAPFDGSRLVFPPVPASLVIGVFYLCMQLILPEAVGGTV 300
KPPSDSYYLIMLHFVMHGQHHKAPFDGSRLVFPPVPASLVIGVFYLCMQLILPEAVGGTV
Sbjct: 241 KPPSDSYYLIMLHFVMHGQHHKAPFDGSRLVFPPVPASLVIGVFYLCMQLILPEAVGGTV 300
Query: 301 FAGGLLGYVLYDMTHYYLHFGSPHKGSYLYSLKAHHVKHHFAHQKSGFGISTKLWDYCFH 360
FAGGLLGYVLYDMTHYYLHFGSPHKGSYLYSLKAHHVKHHFAHQKSGFGISTKLWDYCFH
Sbjct: 301 FAGGLLGYVLYDMTHYYLHFGSPHKGSYLYSLKAHHVKHHFAHQKSGFGISTKLWDYCFH 360
Query: 361 TLTPEKPHLKTQ 372
TLTPEKPHLKTQ
Sbjct: 361 TLTPEKPHLKTQ 372
>gi|83921614 cytochrome b5 outer mitochondrial membrane precursor
[Homo sapiens]
Length = 150
Score = 56.6 bits (135), Expect = 3e-08
Identities = 27/71 (38%), Positives = 44/71 (61%), Gaps = 2/71 (2%)
Query: 15 EVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHSANAR 74
EV +R + W+ R+YD++ F+ HPGGE++L +AG D S + HS++AR
Sbjct: 31 EVAKRNSLKELWLVIHGRVYDVTRFLNEHPGGEEVLLEQAGVDASESFEDV--GHSSDAR 88
Query: 75 RWLEQYYVGEL 85
L+QYY+G++
Sbjct: 89 EMLKQYYIGDI 99
>gi|41281768 cytochrome b-5 isoform 1 [Homo sapiens]
Length = 134
Score = 55.5 bits (132), Expect = 8e-08
Identities = 27/93 (29%), Positives = 51/93 (54%), Gaps = 2/93 (2%)
Query: 11 FSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHS 70
++ E+Q+ + + W+ ++YDL+ F+ HPGGE++LR +AG D + + + HS
Sbjct: 12 YTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDV--GHS 69
Query: 71 ANARRWLEQYYVGELRGEQQGSMENEPVALEET 103
+AR + + +GEL + + + P L T
Sbjct: 70 TDAREMSKTFIIGELHPDDRPKLNKPPETLITT 102
>gi|4503183 cytochrome b-5 isoform 2 [Homo sapiens]
Length = 98
Score = 54.3 bits (129), Expect = 2e-07
Identities = 25/87 (28%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Query: 11 FSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHS 70
++ E+Q+ + + W+ ++YDL+ F+ HPGGE++LR +AG D + + + HS
Sbjct: 12 YTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDV--GHS 69
Query: 71 ANARRWLEQYYVGELRGEQQGSMENEP 97
+AR + + +GEL + + + P
Sbjct: 70 TDAREMSKTFIIGELHPDDRPKLNKPP 96
>gi|214831730 fatty acid desaturase 1 [Homo sapiens]
Length = 501
Score = 45.4 bits (106), Expect = 8e-05
Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 10/98 (10%)
Query: 1 MAPAP---------PPAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLR 51
MAP P P F+ EV +R W+ ++Y++S F R HPGG +++
Sbjct: 58 MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVIS 117
Query: 52 ARAGQDISADLDGPPHRHSANARRWLEQYYVGELRGEQ 89
AGQD + D H + ++++ +GEL EQ
Sbjct: 118 HYAGQD-ATDPFVAFHINKGLVKKYMNSLLIGELSPEQ 154
>gi|74099704 sulfite oxidase [Homo sapiens]
Length = 545
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 26 WVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHSANARRWLEQYYVGEL 85
WV G+ ++D++ FV HPGG L AG + + ++ R L QY +GEL
Sbjct: 101 WVTLGSEVFDVTEFVDLHPGGPSKLMLAAGGPLEPFWALYAVHNQSHVRELLAQYKIGEL 160
Query: 86 RGEQQGSMENEPVALEETQKTDPAMEPRFKV 116
E + + V + DP P KV
Sbjct: 161 NPEDKVA---PTVETSDPYADDPVRHPALKV 188
>gi|74099702 sulfite oxidase [Homo sapiens]
Length = 545
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 26 WVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHSANARRWLEQYYVGEL 85
WV G+ ++D++ FV HPGG L AG + + ++ R L QY +GEL
Sbjct: 101 WVTLGSEVFDVTEFVDLHPGGPSKLMLAAGGPLEPFWALYAVHNQSHVRELLAQYKIGEL 160
Query: 86 RGEQQGSMENEPVALEETQKTDPAMEPRFKV 116
E + + V + DP P KV
Sbjct: 161 NPEDKVA---PTVETSDPYADDPVRHPALKV 188
>gi|74099694 sulfite oxidase [Homo sapiens]
Length = 545
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 3/91 (3%)
Query: 26 WVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHSANARRWLEQYYVGEL 85
WV G+ ++D++ FV HPGG L AG + + ++ R L QY +GEL
Sbjct: 101 WVTLGSEVFDVTEFVDLHPGGPSKLMLAAGGPLEPFWALYAVHNQSHVRELLAQYKIGEL 160
Query: 86 RGEQQGSMENEPVALEETQKTDPAMEPRFKV 116
E + + V + DP P KV
Sbjct: 161 NPEDKVA---PTVETSDPYADDPVRHPALKV 188
>gi|13375616 fatty acid desaturase 3 [Homo sapiens]
Length = 445
Score = 41.6 bits (96), Expect = 0.001
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
Query: 3 PAPP--PAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISA 60
PA P P +F +++ G W+ R+YD+S + + HPGG +L+ +D +
Sbjct: 13 PAQPGAPLPTFCWEQIRAHDQPGDKWLVIERRVYDISRWAQRHPGGSRLIGHHGAED-AT 71
Query: 61 DLDGPPHRHSANARRWLEQYYVGELRGEQ 89
D H+ R++L+ +GEL E+
Sbjct: 72 DAFRAFHQDLNFVRKFLQPLLIGELAPEE 100
>gi|84875541 cytochrome b5 reductase 4 [Homo sapiens]
Length = 521
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/108 (27%), Positives = 47/108 (43%), Gaps = 14/108 (12%)
Query: 15 EVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHSANAR 74
E+++ CW+ +Y++S ++ +HPGGE L AG D + D
Sbjct: 61 ELKKHNKKDDCWICIRGFVYNVSPYMEYHPGGEDELMRAAGSDGTELFD--------QVH 112
Query: 75 RWLEQYYVGELRGEQQGSMENEPVAL----EETQKTDPAMEPRFKVVD 118
RW+ Y L+ G M +P L EE +K M P+ +V D
Sbjct: 113 RWVN--YESMLKECLVGRMAIKPAVLKDYREEEKKVLNGMLPKSQVTD 158
>gi|4758334 fatty acid desaturase 2 [Homo sapiens]
Length = 444
Score = 34.3 bits (77), Expect = 0.19
Identities = 20/80 (25%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 10 SFSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRH 69
+FS E+Q+ W+ ++Y+++ + HPGG++++ AG+D + D H
Sbjct: 20 TFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVIGHYAGED-ATDAFRAFHPD 78
Query: 70 SANARRWLEQYYVGELRGEQ 89
++L+ +GEL E+
Sbjct: 79 LEFVGKFLKPLLIGELAPEE 98
>gi|40255272 xin actin-binding repeat containing 1 [Homo sapiens]
Length = 1843
Score = 32.7 bits (73), Expect = 0.54
Identities = 28/111 (25%), Positives = 41/111 (36%), Gaps = 15/111 (13%)
Query: 3 PAPPPAASFSPSEVQRRLAAGACWVRRGARLYDLSSFVRH-HPGGEQLLRARAGQDISAD 61
P PPP SFS QR+ + +L RH HP + L +D++
Sbjct: 34 PLPPPKESFSKFHQQRQAS-------------ELRRLYRHIHPELRKNLAEAVAEDLAEV 80
Query: 62 LDG-PPHRHSANARRWLEQYYVGELRGEQQGSMENEPVALEETQKTDPAME 111
L P RW+ + + + GE + EPV + Q T E
Sbjct: 81 LGSEEPTEGDVQCMRWIFENWRLDAIGEHERPAAKEPVLCGDVQATSRKFE 131
>gi|52627217 olfactory receptor, family 2, subfamily AT, member 4
[Homo sapiens]
Length = 320
Score = 31.6 bits (70), Expect = 1.2
Identities = 25/110 (22%), Positives = 47/110 (42%), Gaps = 13/110 (11%)
Query: 207 TVAVPKSMFPGLFMLGTFLWSLIEYLIHRFLFHMKPPSDSYYLIMLHF-----VMHGQHH 261
T VPK + LF+LG S L+ +LF S+++ L+++ + + H H+
Sbjct: 80 TTTVPKML--SLFLLGDRFLSFSSCLLQMYLFQSFTCSEAFILVVMAYDRYVAICHPLHY 137
Query: 262 KAPFDGSRLVFPPVPASLVIGVFYLCMQLILPEAVGGTVFAGGLLGYVLY 311
L+ P A+L + + L +P V + A + Y+ +
Sbjct: 138 PV------LMNPQTNATLAASAWLTALLLPIPAVVRTSQMAYNSIAYIYH 181
>gi|62988346 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
[Homo sapiens]
Length = 1043
Score = 31.2 bits (69), Expect = 1.6
Identities = 26/73 (35%), Positives = 32/73 (43%), Gaps = 15/73 (20%)
Query: 3 PAPPPAASFSPSEVQ---RRLAAGA-----CWVRRGARLYDLSSFVRHHPGGEQLLRARA 54
PA P + P E+Q RR+ VRRG L L RH P +LL+ARA
Sbjct: 970 PAARPTGAPQPGELQELERRIEVARERLRQALVRRGQLLAQLGDSARHRP--RRLLQARA 1027
Query: 55 GQDISADLDGPPH 67
A + PPH
Sbjct: 1028 -----APAEAPPH 1035
>gi|40255060 cytochrome b5 domain containing 1 [Homo sapiens]
Length = 228
Score = 30.8 bits (68), Expect = 2.0
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 2/51 (3%)
Query: 11 FSPSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQL--LRARAGQDIS 59
F+P+EV + WV R+YDL+S + + G L + AGQDIS
Sbjct: 20 FTPAEVAQHNRPEDLWVSYLGRVYDLTSLAQEYKGNLLLKPIVEVAGQDIS 70
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 30.0 bits (66), Expect = 3.5
Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 10/85 (11%)
Query: 41 RHHPGGEQLLRARAGQDISADLDGPPH---RHSANARRWLEQYYVGELRGEQQG-SMENE 96
RH GG R + S DG H RH +A R GE RG G + E+
Sbjct: 833 RHGDGGRHGDGYRHPESSSRHTDGHRHGENRHGGSAGRH------GENRGANDGRNGESR 886
Query: 97 PVALEETQKTDPAMEPRFKVVDWDK 121
A K +P MEP+ DK
Sbjct: 887 KEAFNRESKMEPKMEPKVDSSKMDK 911
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 30.0 bits (66), Expect = 3.5
Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 10/85 (11%)
Query: 41 RHHPGGEQLLRARAGQDISADLDGPPH---RHSANARRWLEQYYVGELRGEQQG-SMENE 96
RH GG R + S DG H RH +A R GE RG G + E+
Sbjct: 833 RHGDGGRHGDGYRHPESSSRHTDGHRHGENRHGGSAGRH------GENRGANDGRNGESR 886
Query: 97 PVALEETQKTDPAMEPRFKVVDWDK 121
A K +P MEP+ DK
Sbjct: 887 KEAFNRESKMEPKMEPKVDSSKMDK 911
>gi|46391075 hypothetical protein LOC79949 [Homo sapiens]
Length = 363
Score = 29.6 bits (65), Expect = 4.6
Identities = 14/43 (32%), Positives = 21/43 (48%)
Query: 77 LEQYYVGELRGEQQGSMENEPVALEETQKTDPAMEPRFKVVDW 119
+E Y+ E E S + EP L ETQ D ++ + +DW
Sbjct: 257 MESYFFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDW 299
>gi|239751570 PREDICTED: hypothetical protein XP_002347902 [Homo
sapiens]
Length = 168
Score = 29.3 bits (64), Expect = 6.0
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 16 VQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHSANARR 75
++ R + GAC R A + ++ R PG L+RA A S D PPH RR
Sbjct: 51 IRERRSEGACENRPSAAVPLVTRGGRAAPGPPSLVRAEA---TSGSRDAPPHAFVQLGRR 107
Query: 76 WLEQ 79
L +
Sbjct: 108 CLSR 111
>gi|239746082 PREDICTED: hypothetical protein XP_002343651 [Homo
sapiens]
Length = 168
Score = 29.3 bits (64), Expect = 6.0
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 3/64 (4%)
Query: 16 VQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRARAGQDISADLDGPPHRHSANARR 75
++ R + GAC R A + ++ R PG L+RA A S D PPH RR
Sbjct: 51 IRERRSEGACENRPSAAVPLVTRGGRAAPGPPSLVRAEA---TSGSRDAPPHAFVQLGRR 107
Query: 76 WLEQ 79
L +
Sbjct: 108 CLSR 111
>gi|41393547 neuroblastoma-amplified protein [Homo sapiens]
Length = 2371
Score = 28.9 bits (63), Expect = 7.8
Identities = 20/65 (30%), Positives = 31/65 (47%), Gaps = 3/65 (4%)
Query: 13 PSEVQRRLAAGACWVRRGARLYDLSSFVRHHPGGEQLLRA-RAGQDISADLDGPPHRHSA 71
PS ++ LAA + + LY +F HH GGE + + + + D G P +SA
Sbjct: 1347 PSSIELLLAASSSL--QTEILYQRVNFQIHHEGGENISASPLTSKAVQEDEVGVPGSNSA 1404
Query: 72 NARRW 76
+ RW
Sbjct: 1405 DLLRW 1409
>gi|62865628 sterol-C4-methyl oxidase-like isoform 2 [Homo sapiens]
Length = 162
Score = 28.9 bits (63), Expect = 7.8
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 309 VLYDMTHYYLHFGSPHKGSYLYSLKAHH 336
V+ D HY+LH HK Y Y K HH
Sbjct: 16 VIEDTWHYFLHRLLHHKRIYKYIHKVHH 43
>gi|5803157 sterol-C4-methyl oxidase-like isoform 1 [Homo sapiens]
Length = 293
Score = 28.9 bits (63), Expect = 7.8
Identities = 13/28 (46%), Positives = 15/28 (53%)
Query: 309 VLYDMTHYYLHFGSPHKGSYLYSLKAHH 336
V+ D HY+LH HK Y Y K HH
Sbjct: 147 VIEDTWHYFLHRLLHHKRIYKYIHKVHH 174
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.140 0.463
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,987,461
Number of Sequences: 37866
Number of extensions: 819409
Number of successful extensions: 2403
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2381
Number of HSP's gapped (non-prelim): 24
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.