Guide to the Human Genome
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Search of human proteins with 20336251

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20336251 palmitoyl-protein thioesterase 2 isoform b
precursor [Homo sapiens]
         (308 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20336251 palmitoyl-protein thioesterase 2 isoform b precursor...   649   0.0  
gi|18677774 palmitoyl-protein thioesterase 2 isoform a precursor...   636   0.0  
gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor ...    79   7e-15
gi|217272890 palmitoyl-protein thioesterase 1 isoform 2 precurso...    65   6e-11
gi|21618344 signal transducer and activator of transcription 5B ...    31   1.2  
gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precurs...    29   4.6  
gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs...    29   4.6  
gi|33942072 trinucleotide repeat containing 5 [Homo sapiens]           29   4.6  
gi|134031945 SCO-spondin [Homo sapiens]                                29   6.0  
gi|242117946 hypothetical protein LOC57579 isoform c [Homo sapiens]    28   7.9  
gi|157671939 hypothetical protein LOC57579 isoform b [Homo sapiens]    28   7.9  
gi|157671937 hypothetical protein LOC57579 isoform a [Homo sapiens]    28   7.9  
gi|46240862 GPI deacylase [Homo sapiens]                               28   7.9  

>gi|20336251 palmitoyl-protein thioesterase 2 isoform b precursor
           [Homo sapiens]
          Length = 308

 Score =  649 bits (1674), Expect = 0.0
 Identities = 308/308 (100%), Positives = 308/308 (100%)

Query: 1   MKSCGSMLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRH 60
           MKSCGSMLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRH
Sbjct: 1   MKSCGSMLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRH 60

Query: 61  LLEYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGG 120
           LLEYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGG
Sbjct: 61  LLEYINETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGG 120

Query: 121 LVCRALLSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFS 180
           LVCRALLSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFS
Sbjct: 121 LVCRALLSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFS 180

Query: 181 ICNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPW 240
           ICNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPW
Sbjct: 181 ICNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPW 240

Query: 241 QSSFFGFYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYE 300
           QSSFFGFYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYE
Sbjct: 241 QSSFFGFYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYE 300

Query: 301 TCIEPWLS 308
           TCIEPWLS
Sbjct: 301 TCIEPWLS 308


>gi|18677774 palmitoyl-protein thioesterase 2 isoform a precursor
           [Homo sapiens]
          Length = 302

 Score =  636 bits (1641), Expect = 0.0
 Identities = 302/302 (100%), Positives = 302/302 (100%)

Query: 7   MLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYIN 66
           MLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYIN
Sbjct: 1   MLGLWGQRLPAAWVLLLLPFLPLLLLAAPAPHRASYKPVIVVHGLFDSSYSFRHLLEYIN 60

Query: 67  ETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRAL 126
           ETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRAL
Sbjct: 61  ETHPGTVVTVLDLFDGRESLRPLWEQVQGFREAVVPIMAKAPQGVHLICYSQGGLVCRAL 120

Query: 127 LSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWH 186
           LSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWH
Sbjct: 121 LSVMDDHNVDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYWH 180

Query: 187 DPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFG 246
           DPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFG
Sbjct: 181 DPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGGPDDGVITPWQSSFFG 240

Query: 247 FYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYETCIEPW 306
           FYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYETCIEPW
Sbjct: 241 FYDANETVLEMEEQLVYLRDSFGLKTLLARGAIVRCPMAGISHTAWHSNRTLYETCIEPW 300

Query: 307 LS 308
           LS
Sbjct: 301 LS 302


>gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor
           [Homo sapiens]
          Length = 306

 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 81/292 (27%), Positives = 131/292 (44%), Gaps = 41/292 (14%)

Query: 16  PAAWVLLLLPFLP-------LLLLAAPAPHRASYKPVIVVHGLFDSS---YSFRHLLEYI 65
           P    LL +  LP       L  L  PAP      P+++ HG+ DS     S   + + +
Sbjct: 4   PGCLWLLAVALLPWTCASRALQHLDPPAP-----LPLVIWHGMGDSCCNPLSMGAIKKMV 58

Query: 66  NETHPGTVVTVLDLFDGRESLRPL----WEQVQGFREAVVPIMAKAP---QGVHLICYSQ 118
            +  PG  V  L++  G+  +  +    +  V      V   +AK P   QG + + +SQ
Sbjct: 59  EKKIPGIYVLSLEI--GKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQ 116

Query: 119 GGLVCRALLSVMDDHNVDSFISLSSPQMGQYG------DTDYLKWLFPTSMRSNLYRICY 172
           GG   RA+        + + IS+     G +G      ++ ++       +R  L    Y
Sbjct: 117 GGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHIC----DFIRKTLNAGAY 172

Query: 173 SPWGQEFSI-CNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGG 231
           S   QE  +   YWHDP  +D+Y N S FLA IN ER    +  ++KN + +   V++  
Sbjct: 173 SKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES--YKKNLMALKKFVMVKF 230

Query: 232 PDDGVITPWQSSFFGFY---DANETVLEMEEQLVYLRDSFGLKTLLARGAIV 280
            +D ++ P  S +FGFY    A ET+  ++E  +Y +D  GLK +   G +V
Sbjct: 231 LNDSIVDPVDSEWFGFYRSGQAKETI-PLQETSLYTQDRLGLKEMDNAGQLV 281


>gi|217272890 palmitoyl-protein thioesterase 1 isoform 2 precursor
           [Homo sapiens]
          Length = 203

 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 43/122 (35%), Positives = 65/122 (53%), Gaps = 7/122 (5%)

Query: 163 MRSNLYRICYSPWGQEFSI-CNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFL 221
           +R  L    YS   QE  +   YWHDP  +D+Y N S FLA IN ER    +  ++KN +
Sbjct: 60  IRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES--YKKNLM 117

Query: 222 RVGHLVLIGGPDDGVITPWQSSFFGFY---DANETVLEMEEQLVYLRDSFGLKTLLARGA 278
            +   V++   +D ++ P  S +FGFY    A ET+  ++E  +Y +D  GLK +   G 
Sbjct: 118 ALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETI-PLQETSLYTQDRLGLKEMDNAGQ 176

Query: 279 IV 280
           +V
Sbjct: 177 LV 178


>gi|21618344 signal transducer and activator of transcription 5B
           [Homo sapiens]
          Length = 787

 Score = 31.2 bits (69), Expect = 1.2
 Identities = 39/160 (24%), Positives = 65/160 (40%), Gaps = 35/160 (21%)

Query: 45  VIVVHGLFDSSYSFRHLLEYIN----------ETHPGTVVTVLDLFDG-----RESLRPL 89
           V +   LF++S S  HL +Y            E  PG   T    FDG     ++ L+P 
Sbjct: 531 VFLAQKLFNNSSS--HLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPH 588

Query: 90  WEQ--VQGF--REAVVPIMAKAPQGVHLICYSQ---GGLVC--------RALLSVMDDHN 134
           W    + GF  ++    ++   P G  L+ +S    GG+          R   ++M    
Sbjct: 589 WNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTT 648

Query: 135 VDSFISLSSPQMGQYGDTDYLKWLFPTSMRSNLYRICYSP 174
            D  I   + ++G   D +YL ++FP   +  +Y   Y+P
Sbjct: 649 RDFSIRSLADRLG---DLNYLIYVFPDRPKDEVYSKYYTP 685


>gi|14277685 protocadherin gamma subfamily C, 5 isoform 2 precursor
           [Homo sapiens]
          Length = 878

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 119 GGLVCRALLSVMDDHNVDSFISLSSP--QMGQYGDTDYLK-WLFPTSMRSNLYRICYSP 174
           GG  CR   S   D     F   SSP  Q+   G   Y++  L PT  +S+ YR C+SP
Sbjct: 727 GGQCCRRQDSPSPD-----FYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780


>gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor
           [Homo sapiens]
          Length = 944

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 119 GGLVCRALLSVMDDHNVDSFISLSSP--QMGQYGDTDYLK-WLFPTSMRSNLYRICYSP 174
           GG  CR   S   D     F   SSP  Q+   G   Y++  L PT  +S+ YR C+SP
Sbjct: 727 GGQCCRRQDSPSPD-----FYKQSSPNLQVSSDGTLKYMEVTLRPTDSQSHCYRTCFSP 780


>gi|33942072 trinucleotide repeat containing 5 [Homo sapiens]
          Length = 278

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 15/22 (68%), Positives = 16/22 (72%)

Query: 16 PAAWVLLLLPFLPLLLLAAPAP 37
          PA+  LLLLP L LLLL  PAP
Sbjct: 7  PASRCLLLLPLLLLLLLLLPAP 28


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score = 28.9 bits (63), Expect = 6.0
 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 21/92 (22%)

Query: 149  YGDTDYLKWLFPTSMRSNLYRICYSPWGQEFSICNYW-HDPHHDDLYLNASSFLALINGE 207
            + D D   W F   +++   R+              W HD HH D+ L       L+  E
Sbjct: 2184 WDDLDPAVWTFGRMVQARFVRV--------------WPHDVHHSDVPLQVE----LLGCE 2225

Query: 208  RDHPNATVWRKNFLRV--GHLVLIGGPDDGVI 237
               P A +     LR   G  VL GGP DGV+
Sbjct: 2226 PGSPPAPLCPGVGLRCASGECVLRGGPCDGVL 2257


>gi|242117946 hypothetical protein LOC57579 isoform c [Homo sapiens]
          Length = 1515

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 18/116 (15%)

Query: 45   VIVVHGLFDSSYSFRHLLEYINETHPGTVVTVL-------DLFDGRESL--RPLWEQVQG 95
            ++ VHGL  +S   R +  YI    PG  +  L       D F   +S+  R L E +Q 
Sbjct: 1251 IVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQ- 1309

Query: 96   FREAVVPIMAKAPQGVHLICYSQGGLVCRALLS----VMDDHNVDSFISLSSPQMG 147
                 + I +     +  I +S G L+ R++L+        + + +F+SLS P +G
Sbjct: 1310 ----YIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLNKLHTFLSLSGPHLG 1361


>gi|157671939 hypothetical protein LOC57579 isoform b [Homo sapiens]
          Length = 1302

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 18/116 (15%)

Query: 45   VIVVHGLFDSSYSFRHLLEYINETHPGTVVTVL-------DLFDGRESL--RPLWEQVQG 95
            ++ VHGL  +S   R +  YI    PG  +  L       D F   +S+  R L E +Q 
Sbjct: 1038 IVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQ- 1096

Query: 96   FREAVVPIMAKAPQGVHLICYSQGGLVCRALLS----VMDDHNVDSFISLSSPQMG 147
                 + I +     +  I +S G L+ R++L+        + + +F+SLS P +G
Sbjct: 1097 ----YIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLNKLHTFLSLSGPHLG 1148


>gi|157671937 hypothetical protein LOC57579 isoform a [Homo sapiens]
          Length = 1319

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 18/116 (15%)

Query: 45   VIVVHGLFDSSYSFRHLLEYINETHPGTVVTVL-------DLFDGRESL--RPLWEQVQG 95
            ++ VHGL  +S   R +  YI    PG  +  L       D F   +S+  R L E +Q 
Sbjct: 1055 IVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQ- 1113

Query: 96   FREAVVPIMAKAPQGVHLICYSQGGLVCRALLS----VMDDHNVDSFISLSSPQMG 147
                 + I +     +  I +S G L+ R++L+        + + +F+SLS P +G
Sbjct: 1114 ----YIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLNKLHTFLSLSGPHLG 1165


>gi|46240862 GPI deacylase [Homo sapiens]
          Length = 922

 Score = 28.5 bits (62), Expect = 7.9
 Identities = 13/23 (56%), Positives = 18/23 (78%)

Query: 107 APQGVHLICYSQGGLVCRALLSV 129
           AP+ V +I +S GGLV RALL++
Sbjct: 164 APKSVAIIGHSMGGLVARALLTL 186


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.462 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,759,171
Number of Sequences: 37866
Number of extensions: 569951
Number of successful extensions: 1453
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1444
Number of HSP's gapped (non-prelim): 15
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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