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Search of human proteins with 20270363
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20270363 family with sequence similarity 3, member D [Homo
sapiens]
(224 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20270363 family with sequence similarity 3, member D [Homo sa... 460 e-130
gi|13324682 family 3, member A protein [Homo sapiens] 254 5e-68
gi|91807125 family with sequence similarity 3, member C precurso... 239 1e-63
gi|7661714 family with sequence similarity 3, member C precursor... 239 1e-63
gi|46255030 family with sequence similarity 3, member B isoform ... 134 6e-32
gi|46255032 family with sequence similarity 3, member B isoform ... 133 1e-31
gi|210147552 O-linked mannose beta1,2-N-acetylglucosaminyltransf... 61 9e-10
gi|38638698 KIAA1199 [Homo sapiens] 55 6e-08
gi|209447096 transmembrane protein 2 isoform b [Homo sapiens] 44 1e-04
gi|7019555 transmembrane protein 2 isoform a [Homo sapiens] 44 1e-04
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 29 3.7
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 29 3.7
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 29 3.7
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 29 3.7
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 28 6.3
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 28 6.3
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 28 6.3
gi|27262622 neuron navigator 1 [Homo sapiens] 28 6.3
gi|5174457 kinetochore associated 2 [Homo sapiens] 28 8.3
>gi|20270363 family with sequence similarity 3, member D [Homo
sapiens]
Length = 224
Score = 460 bits (1183), Expect = e-130
Identities = 224/224 (100%), Positives = 224/224 (100%)
Query: 1 MRVSGVLRLLALIFAIVTTWMFIRSYMSFSMKTIRLPRWLAASPTKEIQVKKYKCGLIKP 60
MRVSGVLRLLALIFAIVTTWMFIRSYMSFSMKTIRLPRWLAASPTKEIQVKKYKCGLIKP
Sbjct: 1 MRVSGVLRLLALIFAIVTTWMFIRSYMSFSMKTIRLPRWLAASPTKEIQVKKYKCGLIKP 60
Query: 61 CPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNVGRGLNIALVNGTTGAVLGQKAFD 120
CPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNVGRGLNIALVNGTTGAVLGQKAFD
Sbjct: 61 CPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNVGRGLNIALVNGTTGAVLGQKAFD 120
Query: 121 MYSGDVMHLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYAKQLGFRDSWV 180
MYSGDVMHLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYAKQLGFRDSWV
Sbjct: 121 MYSGDVMHLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYAKQLGFRDSWV 180
Query: 181 FIGAKDLRGKSPFEQFLKNSPDTNKYEGWPELLEMEGCMPPKPF 224
FIGAKDLRGKSPFEQFLKNSPDTNKYEGWPELLEMEGCMPPKPF
Sbjct: 181 FIGAKDLRGKSPFEQFLKNSPDTNKYEGWPELLEMEGCMPPKPF 224
>gi|13324682 family 3, member A protein [Homo sapiens]
Length = 230
Score = 254 bits (648), Expect = 5e-68
Identities = 121/224 (54%), Positives = 164/224 (73%), Gaps = 4/224 (1%)
Query: 1 MRVSGVLRLLALIFAIVTTWMFIRSYMSFSMKTIRLPRWLAASPTKEI----QVKKYKCG 56
MR++G LR++ L+ ++ TW+ + + + L SP + + +KYKCG
Sbjct: 1 MRLAGPLRIVVLVVSVGVTWIVVSILLGGPGSGFPRIQQLFTSPESSVTAAPRARKYKCG 60
Query: 57 LIKPCPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNVGRGLNIALVNGTTGAVLGQ 116
L +PCP + AF++ SGAANV+GP +C ED+M+MS VK+NVGRGLNIALVNG +G ++
Sbjct: 61 LPQPCPEEHLAFRVVSGAANVIGPKICLEDKMLMSSVKDNVGRGLNIALVNGVSGELIEA 120
Query: 117 KAFDMYSGDVMHLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYAKQLGFR 176
+AFDM++GDV L+KF++ + G LV VASYDDP TKMN+E+RKLFS+LGS AK+L FR
Sbjct: 121 RAFDMWAGDVNDLLKFIRPLHEGTLVFVASYDDPATKMNEETRKLFSELGSRNAKELAFR 180
Query: 177 DSWVFIGAKDLRGKSPFEQFLKNSPDTNKYEGWPELLEMEGCMP 220
DSWVF+GAK ++ KSPFEQ +KNS +NKYEG PE LEMEGC+P
Sbjct: 181 DSWVFVGAKGVQNKSPFEQHVKNSKHSNKYEGCPEALEMEGCIP 224
>gi|91807125 family with sequence similarity 3, member C precursor
[Homo sapiens]
Length = 227
Score = 239 bits (610), Expect = 1e-63
Identities = 114/225 (50%), Positives = 151/225 (67%), Gaps = 3/225 (1%)
Query: 1 MRVSGVLRLLALIFAIVTTWMFIRSYMSFSMKTIR---LPRWLAASPTKEIQVKKYKCGL 57
MRV+G +L+ + + T+ I M R + + + +YKCG+
Sbjct: 1 MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAARSTKPPRYKCGI 60
Query: 58 IKPCPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNVGRGLNIALVNGTTGAVLGQK 117
K CP +FAFK+ SGAANVVGP +C ED ++MS VKNNVGRG+N+AL NG TG VL K
Sbjct: 61 SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK 120
Query: 118 AFDMYSGDVMHLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYAKQLGFRD 177
FDM+ GDV ++FLK I G +VL+ +YDD TK+NDE+R+L +DLGS+ LGFRD
Sbjct: 121 YFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFRD 180
Query: 178 SWVFIGAKDLRGKSPFEQFLKNSPDTNKYEGWPELLEMEGCMPPK 222
+WVF G K ++ KSPFEQ +KN+ DTNKYEGWPE++EMEGC+P K
Sbjct: 181 NWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQK 225
>gi|7661714 family with sequence similarity 3, member C precursor
[Homo sapiens]
Length = 227
Score = 239 bits (610), Expect = 1e-63
Identities = 114/225 (50%), Positives = 151/225 (67%), Gaps = 3/225 (1%)
Query: 1 MRVSGVLRLLALIFAIVTTWMFIRSYMSFSMKTIR---LPRWLAASPTKEIQVKKYKCGL 57
MRV+G +L+ + + T+ I M R + + + +YKCG+
Sbjct: 1 MRVAGAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAARSTKPPRYKCGI 60
Query: 58 IKPCPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNVGRGLNIALVNGTTGAVLGQK 117
K CP +FAFK+ SGAANVVGP +C ED ++MS VKNNVGRG+N+AL NG TG VL K
Sbjct: 61 SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK 120
Query: 118 AFDMYSGDVMHLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYAKQLGFRD 177
FDM+ GDV ++FLK I G +VL+ +YDD TK+NDE+R+L +DLGS+ LGFRD
Sbjct: 121 YFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFRD 180
Query: 178 SWVFIGAKDLRGKSPFEQFLKNSPDTNKYEGWPELLEMEGCMPPK 222
+WVF G K ++ KSPFEQ +KN+ DTNKYEGWPE++EMEGC+P K
Sbjct: 181 NWVFCGGKGIKTKSPFEQHIKNNKDTNKYEGWPEVVEMEGCIPQK 225
>gi|46255030 family with sequence similarity 3, member B isoform a
[Homo sapiens]
Length = 235
Score = 134 bits (337), Expect = 6e-32
Identities = 75/228 (32%), Positives = 124/228 (54%), Gaps = 15/228 (6%)
Query: 5 GVLRLLALIFAIVTTW--------MFIRSYMSFSMKTIRLPRWLAASPTKEIQV-KKYKC 55
G+L+++ ++FA + W + + +S + +IR + P + V K+ KC
Sbjct: 7 GLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRS---IGERPVLKAPVPKRQKC 63
Query: 56 GLIKPCPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNVGRGLNIALVNGTTGAVLG 115
PCP++ +A+++ SG +CFED ++M NV RG+NIA+VN TG V
Sbjct: 64 DHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTA 123
Query: 116 QKAFDMYSGDVM-HLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYAKQLG 174
+ FDMY GD + KF++ +L+ + +YDD T++N++++ LGS + +
Sbjct: 124 TRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMK 183
Query: 175 FRDSWVFIGAKDLRGKSPFEQFLKNSPD--TNKYEGWPELLEMEGCMP 220
FR SWVFI AK L S ++ N D N+Y GWP +++EGC+P
Sbjct: 184 FRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIP 231
>gi|46255032 family with sequence similarity 3, member B isoform b
[Homo sapiens]
Length = 187
Score = 133 bits (334), Expect = 1e-31
Identities = 69/186 (37%), Positives = 105/186 (56%), Gaps = 7/186 (3%)
Query: 38 RWLAASPTKEIQVKKYKCGLIKPCPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNV 97
R LA +P K+ KC PCP++ +A+++ SG +CFED ++M NV
Sbjct: 2 RPLAGAPVP----KRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNV 57
Query: 98 GRGLNIALVNGTTGAVLGQKAFDMYSGDVM-HLVKFLKEIPGGALVLVASYDDPGTKMND 156
RG+NIA+VN TG V + FDMY GD + KF++ +L+ + +YDD T++N+
Sbjct: 58 ARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNN 117
Query: 157 ESRKLFSDLGSSYAKQLGFRDSWVFIGAKDLRGKSPFEQFLKNSPD--TNKYEGWPELLE 214
+++ LGS + + FR SWVFI AK L S ++ N D N+Y GWP ++
Sbjct: 118 DAKNAIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQ 177
Query: 215 MEGCMP 220
+EGC+P
Sbjct: 178 IEGCIP 183
>gi|210147552 O-linked mannose
beta1,2-N-acetylglucosaminyltransferase [Homo sapiens]
Length = 660
Score = 60.8 bits (146), Expect = 9e-10
Identities = 37/120 (30%), Positives = 63/120 (52%), Gaps = 5/120 (4%)
Query: 98 GRGLNIALVNGTTGAVLGQKAFDMYSG-DVMHLVKFLKEIPGGALVLVASYDDPGTKMND 156
GRG+++ ++N TG V+ ++ FD YS + +V FL + G +++ D+ + D
Sbjct: 128 GRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGRVLICTVKDEGSFHLKD 187
Query: 157 ESRKLFSDLGSSYAKQLGFRDSWVFIGAKDLRGKSPFEQFLKNSPDTNKYEGWPELLEME 216
++ L LGS LG+RD+W F+G K G F + SP + + G P LL+ +
Sbjct: 188 TAKALLRSLGSQAGPALGWRDTWAFVGRK---GGPVFGEKHSKSPALSSW-GDPVLLKTD 243
>gi|38638698 KIAA1199 [Homo sapiens]
Length = 1361
Score = 54.7 bits (130), Expect = 6e-08
Identities = 28/89 (31%), Positives = 48/89 (53%), Gaps = 2/89 (2%)
Query: 99 RGLNIALVNGTTGAVLGQKAFDMYSG--DVMHLVKFLKEIPGGALVLVASYDDPGTKMND 156
RG+ + +++ +G V+ FD Y + LV++L +P G ++ VA D+ ++D
Sbjct: 187 RGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDD 246
Query: 157 ESRKLFSDLGSSYAKQLGFRDSWVFIGAK 185
+RK + LGS + LGFR W F+ K
Sbjct: 247 MARKAMTKLGSKHFLHLGFRHPWSFLTVK 275
>gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]
Length = 1320
Score = 43.5 bits (101), Expect = 1e-04
Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 94 KNNVGRGLNIALVNGTTGAVLGQKAFDM--YSGDVMHLVKFLKEIPGGALVLVASYDDPG 151
+ + RGLN+ +++ T +L + FD Y + L +FL+ G +V +A D
Sbjct: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
Query: 152 TKMNDESRKLFSD-LGSSYAKQLGFRDSWVFIGAKD 186
+ + ++ + LGS + LG+R +W +G D
Sbjct: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVID 355
>gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]
Length = 1383
Score = 43.5 bits (101), Expect = 1e-04
Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 94 KNNVGRGLNIALVNGTTGAVLGQKAFDM--YSGDVMHLVKFLKEIPGGALVLVASYDDPG 151
+ + RGLN+ +++ T +L + FD Y + L +FL+ G +V +A D
Sbjct: 260 EKDFSRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAA 319
Query: 152 TKMNDESRKLFSD-LGSSYAKQLGFRDSWVFIGAKD 186
+ + ++ + LGS + LG+R +W +G D
Sbjct: 320 KSLLQGTIQMIQERLGSELIQGLGYRQAWALVGVID 355
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 28.9 bits (63), Expect = 3.7
Identities = 10/24 (41%), Positives = 15/24 (62%)
Query: 195 QFLKNSPDTNKYEGWPELLEMEGC 218
+ L N P+ K +GW + +MEGC
Sbjct: 1073 KILHNDPEVEKKQGWTTVGDMEGC 1096
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 28.9 bits (63), Expect = 3.7
Identities = 10/24 (41%), Positives = 15/24 (62%)
Query: 195 QFLKNSPDTNKYEGWPELLEMEGC 218
+ L N P+ K +GW + +MEGC
Sbjct: 1064 KILHNDPEVEKKQGWTTVGDMEGC 1087
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 28.9 bits (63), Expect = 3.7
Identities = 10/24 (41%), Positives = 15/24 (62%)
Query: 195 QFLKNSPDTNKYEGWPELLEMEGC 218
+ L N P+ K +GW + +MEGC
Sbjct: 1093 KILHNDPEVEKKQGWTTVGDMEGC 1116
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 28.9 bits (63), Expect = 3.7
Identities = 10/24 (41%), Positives = 15/24 (62%)
Query: 195 QFLKNSPDTNKYEGWPELLEMEGC 218
+ L N P+ K +GW + +MEGC
Sbjct: 1056 KILHNDPEVEKKQGWTTVGDMEGC 1079
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 28.1 bits (61), Expect = 6.3
Identities = 9/25 (36%), Positives = 16/25 (64%)
Query: 195 QFLKNSPDTNKYEGWPELLEMEGCM 219
+ L N P+ K +GW + ++EGC+
Sbjct: 973 KILHNDPEVEKKQGWTTVGDLEGCV 997
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 28.1 bits (61), Expect = 6.3
Identities = 9/25 (36%), Positives = 16/25 (64%)
Query: 195 QFLKNSPDTNKYEGWPELLEMEGCM 219
+ L N P+ K +GW + ++EGC+
Sbjct: 919 KILHNDPEVEKKQGWTTVGDLEGCV 943
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 28.1 bits (61), Expect = 6.3
Identities = 9/25 (36%), Positives = 16/25 (64%)
Query: 195 QFLKNSPDTNKYEGWPELLEMEGCM 219
+ L N P+ K +GW + ++EGC+
Sbjct: 1081 KILHNDPEVEKKQGWTTVGDLEGCV 1105
>gi|27262622 neuron navigator 1 [Homo sapiens]
Length = 1874
Score = 28.1 bits (61), Expect = 6.3
Identities = 17/55 (30%), Positives = 27/55 (49%), Gaps = 1/55 (1%)
Query: 116 QKAFDMYSGDVMHLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYA 170
+ AF++YSG M L E P G ++ S+ DP ++ L S S+Y+
Sbjct: 1019 EAAFELYSGSQMGSTLSLAERPKG-MIRSGSFRDPTDDVHGSVLSLASSASSTYS 1072
>gi|5174457 kinetochore associated 2 [Homo sapiens]
Length = 642
Score = 27.7 bits (60), Expect = 8.3
Identities = 12/28 (42%), Positives = 17/28 (60%)
Query: 143 LVASYDDPGTKMNDESRKLFSDLGSSYA 170
L SY+ P TK +E ++F DLG +A
Sbjct: 136 LCPSYELPDTKFEEEVPRIFKDLGYPFA 163
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,888,817
Number of Sequences: 37866
Number of extensions: 387494
Number of successful extensions: 622
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 598
Number of HSP's gapped (non-prelim): 19
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.