Guide to the Human Genome
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Search of human proteins with 20127454

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20127454 5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase/IMP cyclohydrolase [Homo sapiens]
         (592 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20127454 5-aminoimidazole-4-carboxamide ribonucleotide formyl...  1168   0.0  
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]                  34   0.43 
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma...    30   4.8  
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ...    30   4.8  
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ...    30   4.8  
gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo ...    30   4.8  
gi|21703346 spartin [Homo sapiens]                                     30   6.2  
gi|214830187 spartin [Homo sapiens]                                    30   6.2  
gi|214830109 spartin [Homo sapiens]                                    30   6.2  
gi|214830079 spartin [Homo sapiens]                                    30   6.2  
gi|33859670 leucine-rich repeats and calponin homology (CH) doma...    30   6.2  
gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]       30   8.2  
gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]       30   8.2  
gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]       30   8.2  
gi|59939900 opioid binding protein/cell adhesion molecule-like i...    30   8.2  
gi|4505505 opioid binding protein/cell adhesion molecule-like is...    30   8.2  

>gi|20127454 5-aminoimidazole-4-carboxamide ribonucleotide
           formyltransferase/IMP cyclohydrolase [Homo sapiens]
          Length = 592

 Score = 1168 bits (3021), Expect = 0.0
 Identities = 592/592 (100%), Positives = 592/592 (100%)

Query: 1   MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM 60
           MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
Sbjct: 1   MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM 60

Query: 61  LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA 120
           LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA
Sbjct: 61  LGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEA 120

Query: 121 VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFT 180
           VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFT
Sbjct: 121 VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFT 180

Query: 181 HTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINL 240
           HTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINL
Sbjct: 181 HTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINL 240

Query: 241 CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS 300
           CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
Sbjct: 241 CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS 300

Query: 301 AAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNG 360
           AAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNG
Sbjct: 301 AAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNG 360

Query: 361 NYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIV 420
           NYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIV
Sbjct: 361 NYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIV 420

Query: 421 ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT 480
           ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
Sbjct: 421 ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT 480

Query: 481 GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDA 540
           GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDA
Sbjct: 481 GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDA 540

Query: 541 FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH 592
           FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
Sbjct: 541 FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH 592


>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
          Length = 819

 Score = 33.9 bits (76), Expect = 0.43
 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 22/108 (20%)

Query: 205 PLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALG------ 258
           P+RY + PH  P + +++QP+   T+   AP    L     AW  +  L   LG      
Sbjct: 407 PIRYSILPHSDPERCFSIQPE-EGTIHTAAP----LDREARAWHNLTVLATELGWSWGPE 461

Query: 259 ---IP-------AAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTL 296
              +P       A A+    SP G+AVGIP  +  A+   V    +TL
Sbjct: 462 RGWVPLLVAEWSAPAAPPQRSPVGSAVGIP-QDSSAQASRVQVAIQTL 508


>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
           isoform 2 [Homo sapiens]
          Length = 527

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 27/111 (24%), Positives = 51/111 (45%), Gaps = 6/111 (5%)

Query: 92  DFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHA---RVTVVCEP 148
           +F++ R  +    P        G   +  + +   GGV   ++++  H    + TVV   
Sbjct: 313 NFSVGRQSSAPASPAASAAGLAGQAAKSLLNKKSDGGVKKRKSSSSVHLMEPQTTVVHNA 372

Query: 149 EDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSK 199
            D +  STE  ++ ++D  L+ R+Q  +K    T Q  EAI++   + Y+K
Sbjct: 373 TDGIKGSTESCNTTTEDEDLKVRKQEIIKI---TEQLIEAINNGDFEAYTK 420


>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
           sapiens]
          Length = 788

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 16/77 (20%)

Query: 135 AAKNHARV-TVVCEPEDYVVVSTEMQSS--------ESKDTSL-ETRRQLALKAFTHTAQ 184
           AA+ H ++  V  E E+YV    E QS         E+ D  L ET  QL L A+ + +Q
Sbjct: 541 AAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGL-AYGYNSQ 599

Query: 185 YDEAISDYFRKQYSKGV 201
           YDEA++     Q+SK +
Sbjct: 600 YDEAVA-----QFSKSI 611


>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
           sapiens]
          Length = 790

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 16/77 (20%)

Query: 135 AAKNHARV-TVVCEPEDYVVVSTEMQSS--------ESKDTSL-ETRRQLALKAFTHTAQ 184
           AA+ H ++  V  E E+YV    E QS         E+ D  L ET  QL L A+ + +Q
Sbjct: 543 AAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGL-AYGYNSQ 601

Query: 185 YDEAISDYFRKQYSKGV 201
           YDEA++     Q+SK +
Sbjct: 602 YDEAVA-----QFSKSI 613


>gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo
           sapiens]
          Length = 449

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 28/77 (36%), Positives = 40/77 (51%), Gaps = 16/77 (20%)

Query: 135 AAKNHARV-TVVCEPEDYVVVSTEMQSS--------ESKDTSL-ETRRQLALKAFTHTAQ 184
           AA+ H ++  V  E E+YV    E QS         E+ D  L ET  QL L A+ + +Q
Sbjct: 202 AAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGL-AYGYNSQ 260

Query: 185 YDEAISDYFRKQYSKGV 201
           YDEA++     Q+SK +
Sbjct: 261 YDEAVA-----QFSKSI 272


>gi|21703346 spartin [Homo sapiens]
          Length = 666

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 21/57 (36%), Positives = 28/57 (49%), Gaps = 5/57 (8%)

Query: 229 TVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASF---KHVSPAGAAVGIPLSED 282
           TVLN  PGF+ +CD L  + LV +    L   A A       +  AG  VG+ LS +
Sbjct: 260 TVLNRPPGFLQVCDWL--YPLVPDRSPVLKCTAGAYMFPDTMLQAAGCFVGVVLSSE 314


>gi|214830187 spartin [Homo sapiens]
          Length = 666

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 21/57 (36%), Positives = 28/57 (49%), Gaps = 5/57 (8%)

Query: 229 TVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASF---KHVSPAGAAVGIPLSED 282
           TVLN  PGF+ +CD L  + LV +    L   A A       +  AG  VG+ LS +
Sbjct: 260 TVLNRPPGFLQVCDWL--YPLVPDRSPVLKCTAGAYMFPDTMLQAAGCFVGVVLSSE 314


>gi|214830109 spartin [Homo sapiens]
          Length = 666

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 21/57 (36%), Positives = 28/57 (49%), Gaps = 5/57 (8%)

Query: 229 TVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASF---KHVSPAGAAVGIPLSED 282
           TVLN  PGF+ +CD L  + LV +    L   A A       +  AG  VG+ LS +
Sbjct: 260 TVLNRPPGFLQVCDWL--YPLVPDRSPVLKCTAGAYMFPDTMLQAAGCFVGVVLSSE 314


>gi|214830079 spartin [Homo sapiens]
          Length = 666

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 21/57 (36%), Positives = 28/57 (49%), Gaps = 5/57 (8%)

Query: 229 TVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASF---KHVSPAGAAVGIPLSED 282
           TVLN  PGF+ +CD L  + LV +    L   A A       +  AG  VG+ LS +
Sbjct: 260 TVLNRPPGFLQVCDWL--YPLVPDRSPVLKCTAGAYMFPDTMLQAAGCFVGVVLSSE 314


>gi|33859670 leucine-rich repeats and calponin homology (CH) domain
           containing 1 [Homo sapiens]
          Length = 728

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 50/208 (24%), Positives = 76/208 (36%), Gaps = 23/208 (11%)

Query: 362 YCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVA 421
           Y  +Q  Q    D   + T+   HL Q   +G  D    S V + N D   SA       
Sbjct: 286 YLSIQACQIKTADSLYLHTMERPHLHQHVEDGKKDSD--SGVGSDNGDKRLSATEPSDED 343

Query: 422 TIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWW-LRHHPQVLSMKFKT 480
           T+++    SN +   +  Q+I           C RL+  K  +    +  P +L     +
Sbjct: 344 TVSLNVPMSNIM---EEEQII-------KEDSCHRLSPVKGEFHQEFQPEPSLLGDSTNS 393

Query: 481 GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDA 540
           G +R       DQ+     G   + + +KA  E+  ELL   E   W    TE  ISS  
Sbjct: 394 GEER-------DQFTDRADGLHSEFMNYKARAEDCEELLRIEEDVHW---QTEGIISSSK 443

Query: 541 FFPFRDNVDRAKRSGVAYIAAPSGSAAD 568
                  +    R  V  +  P+G + D
Sbjct: 444 DQDMDIAMIEQLREAVDLLQDPNGLSTD 471


>gi|169167742 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 494

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 78  ARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAK 137
           A ++PE   +       L+R    N    ++T+   GV+VEEA ++ D  G T L  A  
Sbjct: 72  AESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEA-QETDRNGRTGLIVAC- 129

Query: 138 NHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQ 173
            H  V  V    +   V    Q SE  +T+L T  Q
Sbjct: 130 YHGFVDTVVALAECPHVDVNWQDSEG-NTALITAAQ 164


>gi|113416996 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 1006

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 78  ARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAK 137
           A ++PE   +       L+R    N    ++T+   GV+VEEA ++ D  G T L  A  
Sbjct: 584 AESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEA-QETDRNGRTGLIVAC- 641

Query: 138 NHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQ 173
            H  V  V    +   V    Q SE  +T+L T  Q
Sbjct: 642 YHGFVDTVVALAECPHVDVNWQDSEG-NTALITAAQ 676


>gi|239742483 PREDICTED: ankyrin repeat domain 33B [Homo sapiens]
          Length = 494

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 78  ARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAK 137
           A ++PE   +       L+R    N    ++T+   GV+VEEA ++ D  G T L  A  
Sbjct: 72  AESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEA-QETDRNGRTGLIVAC- 129

Query: 138 NHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQ 173
            H  V  V    +   V    Q SE  +T+L T  Q
Sbjct: 130 YHGFVDTVVALAECPHVDVNWQDSEG-NTALITAAQ 164


>gi|59939900 opioid binding protein/cell adhesion molecule-like
           isoform b preproprotein [Homo sapiens]
          Length = 338

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 24/109 (22%), Positives = 38/109 (34%), Gaps = 9/109 (8%)

Query: 385 HLSQKRNNGVVDKSLFSNVVTKNKDLPE----SALRDLIVATIAVKYTQSNSVCYAKNGQ 440
           HLS K   G V +  +  +    +D       SAL D+    +       N   Y    +
Sbjct: 164 HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAK 223

Query: 441 VIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISN 489
             G+  GQ+  + C   A   A + W +        +  TG+    I N
Sbjct: 224 NTGVSVGQKGILSCEASAVPMAEFQWFKE-----ETRLATGLDGMRIEN 267


>gi|4505505 opioid binding protein/cell adhesion molecule-like
           isoform a preproprotein [Homo sapiens]
          Length = 345

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 24/109 (22%), Positives = 38/109 (34%), Gaps = 9/109 (8%)

Query: 385 HLSQKRNNGVVDKSLFSNVVTKNKDLPE----SALRDLIVATIAVKYTQSNSVCYAKNGQ 440
           HLS K   G V +  +  +    +D       SAL D+    +       N   Y    +
Sbjct: 171 HLSVKEGQGFVSEDEYLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPPYISKAK 230

Query: 441 VIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISN 489
             G+  GQ+  + C   A   A + W +        +  TG+    I N
Sbjct: 231 NTGVSVGQKGILSCEASAVPMAEFQWFKE-----ETRLATGLDGMRIEN 274


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,751,749
Number of Sequences: 37866
Number of extensions: 877243
Number of successful extensions: 2173
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2164
Number of HSP's gapped (non-prelim): 25
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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