Guide to the Human Genome
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Search of human proteins with 20070252

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20070252 interleukin 1 family, member 8 isoform 1 [Homo
sapiens]
         (164 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20070252 interleukin 1 family, member 8 isoform 1 [Homo sapiens]   343   3e-95
gi|27894313 interleukin 1 family, member 8 isoform 2 [Homo sapiens]   178   2e-45
gi|7657092 interleukin 1 family, member 6 (epsilon) [Homo sapiens]     82   2e-16
gi|9665234 interleukin 1 family, member 9 [Homo sapiens]               79   2e-15
gi|27894296 interleukin 1 family, member 7 isoform 2 [Homo sapiens]    49   2e-06
gi|20127524 interleukin 1 family, member 7 isoform 1 proprotein ...    49   2e-06
gi|27894302 interleukin 1 family, member 7 isoform 5 [Homo sapiens]    49   2e-06
gi|27894300 interleukin 1 family, member 7 isoform 4 [Homo sapiens]    32   0.32 
gi|27894298 interleukin 1 family, member 7 isoform 3 [Homo sapiens]    32   0.32 
gi|27894307 interleukin 1 family, member 10 [Homo sapiens]             30   0.72 
gi|27894304 interleukin 1 family, member 10 [Homo sapiens]             30   0.72 
gi|10835145 interleukin 1, beta proprotein [Homo sapiens]              29   1.6  
gi|76096366 phospholipase B1 [Homo sapiens]                            29   2.1  
gi|41462397 RAN guanine nucleotide release factor [Homo sapiens]       29   2.1  

>gi|20070252 interleukin 1 family, member 8 isoform 1 [Homo sapiens]
          Length = 164

 Score =  343 bits (881), Expect = 3e-95
 Identities = 164/164 (100%), Positives = 164/164 (100%)

Query: 1   MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGN 60
           MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGN
Sbjct: 1   MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGN 60

Query: 61  MVYLGIKGKDLCLFCAEIQGKPTLQLKLQGSQDNIGKDTCWKLVGIHTCINLDVRESCFM 120
           MVYLGIKGKDLCLFCAEIQGKPTLQLKLQGSQDNIGKDTCWKLVGIHTCINLDVRESCFM
Sbjct: 61  MVYLGIKGKDLCLFCAEIQGKPTLQLKLQGSQDNIGKDTCWKLVGIHTCINLDVRESCFM 120

Query: 121 GTLDQWGIGVGRKKWKSSFQHHHLRKKDKDFSSMRTNIGMPGRM 164
           GTLDQWGIGVGRKKWKSSFQHHHLRKKDKDFSSMRTNIGMPGRM
Sbjct: 121 GTLDQWGIGVGRKKWKSSFQHHHLRKKDKDFSSMRTNIGMPGRM 164


>gi|27894313 interleukin 1 family, member 8 isoform 2 [Homo
          sapiens]
          Length = 157

 Score =  178 bits (452), Expect = 2e-45
 Identities = 88/93 (94%), Positives = 89/93 (95%)

Query: 1  MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGN 60
          MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGN
Sbjct: 1  MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGN 60

Query: 61 MVYLGIKGKDLCLFCAEIQGKPTLQLKLQGSQD 93
          MVYLGIKGKDLCLFCAEIQGKPTLQLK +   D
Sbjct: 61 MVYLGIKGKDLCLFCAEIQGKPTLQLKEKNIMD 93


>gi|7657092 interleukin 1 family, member 6 (epsilon) [Homo
          sapiens]
          Length = 158

 Score = 82.4 bits (202), Expect = 2e-16
 Identities = 38/85 (44%), Positives = 55/85 (64%)

Query: 9  PKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGNMVYLGIKG 68
          P+  +I+D    VWVL   +LIA P    + PVT+ LI+CR  E  +K++GN +YLG+ G
Sbjct: 10 PQQGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNG 69

Query: 69 KDLCLFCAEIQGKPTLQLKLQGSQD 93
           +LCL CA++  +PTLQLK +   D
Sbjct: 70 LNLCLMCAKVGDQPTLQLKEKDIMD 94


>gi|9665234 interleukin 1 family, member 9 [Homo sapiens]
          Length = 169

 Score = 78.6 bits (192), Expect = 2e-15
 Identities = 37/94 (39%), Positives = 57/94 (60%)

Query: 4   QREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGNMVY 63
           Q    P +  I D  Q VW L G +L+A P S S+ PVT+ +I C+  E  ++ +G+ +Y
Sbjct: 17  QSMCKPITGTINDLNQQVWTLQGQNLVAVPRSDSVTPVTVAVITCKYPEALEQGRGDPIY 76

Query: 64  LGIKGKDLCLFCAEIQGKPTLQLKLQGSQDNIGK 97
           LGI+  ++CL+C ++  +PTLQLK Q   D  G+
Sbjct: 77  LGIQNPEMCLYCEKVGEQPTLQLKEQKIMDLYGQ 110


>gi|27894296 interleukin 1 family, member 7 isoform 2 [Homo sapiens]
          Length = 197

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 3/81 (3%)

Query: 9   PKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGNMVYLGIKG 68
           PK ++I D    V VL   +LIA P    I+P     +A      +  EKG+ + LG+  
Sbjct: 36  PKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALA-SSLSSASAEKGSPILLGVSK 94

Query: 69  KDLCLFCAEIQGK--PTLQLK 87
            + CL+C + +G+  P+LQLK
Sbjct: 95  GEFCLYCDKDKGQSHPSLQLK 115


>gi|20127524 interleukin 1 family, member 7 isoform 1 proprotein
           [Homo sapiens]
          Length = 218

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 3/81 (3%)

Query: 9   PKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGNMVYLGIKG 68
           PK ++I D    V VL   +LIA P    I+P     +A      +  EKG+ + LG+  
Sbjct: 57  PKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALA-SSLSSASAEKGSPILLGVSK 115

Query: 69  KDLCLFCAEIQGK--PTLQLK 87
            + CL+C + +G+  P+LQLK
Sbjct: 116 GEFCLYCDKDKGQSHPSLQLK 136


>gi|27894302 interleukin 1 family, member 7 isoform 5 [Homo sapiens]
          Length = 192

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 3/81 (3%)

Query: 9   PKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGNMVYLGIKG 68
           PK ++I D    V VL   +LIA P    I+P     +A      +  EKG+ + LG+  
Sbjct: 31  PKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALA-SSLSSASAEKGSPILLGVSK 89

Query: 69  KDLCLFCAEIQGK--PTLQLK 87
            + CL+C + +G+  P+LQLK
Sbjct: 90  GEFCLYCDKDKGQSHPSLQLK 110


>gi|27894300 interleukin 1 family, member 7 isoform 4 [Homo
          sapiens]
          Length = 178

 Score = 31.6 bits (70), Expect = 0.32
 Identities = 14/33 (42%), Positives = 23/33 (69%), Gaps = 2/33 (6%)

Query: 57 EKGNMVYLGIKGKDLCLFCAEIQGK--PTLQLK 87
          EKG+ + LG+   + CL+C + +G+  P+LQLK
Sbjct: 64 EKGSPILLGVSKGEFCLYCDKDKGQSHPSLQLK 96


>gi|27894298 interleukin 1 family, member 7 isoform 3 [Homo
          sapiens]
          Length = 157

 Score = 31.6 bits (70), Expect = 0.32
 Identities = 14/33 (42%), Positives = 23/33 (69%), Gaps = 2/33 (6%)

Query: 57 EKGNMVYLGIKGKDLCLFCAEIQGK--PTLQLK 87
          EKG+ + LG+   + CL+C + +G+  P+LQLK
Sbjct: 43 EKGSPILLGVSKGEFCLYCDKDKGQSHPSLQLK 75


>gi|27894307 interleukin 1 family, member 10 [Homo sapiens]
          Length = 152

 Score = 30.4 bits (67), Expect = 0.72
 Identities = 12/26 (46%), Positives = 18/26 (69%)

Query: 62 VYLGIKGKDLCLFCAEIQGKPTLQLK 87
          ++LGI+G   CL C E +  P+LQL+
Sbjct: 57 IFLGIQGGSRCLACVETEEGPSLQLE 82


>gi|27894304 interleukin 1 family, member 10 [Homo sapiens]
          Length = 152

 Score = 30.4 bits (67), Expect = 0.72
 Identities = 12/26 (46%), Positives = 18/26 (69%)

Query: 62 VYLGIKGKDLCLFCAEIQGKPTLQLK 87
          ++LGI+G   CL C E +  P+LQL+
Sbjct: 57 IFLGIQGGSRCLACVETEEGPSLQLE 82


>gi|10835145 interleukin 1, beta proprotein [Homo sapiens]
          Length = 269

 Score = 29.3 bits (64), Expect = 1.6
 Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 6/77 (7%)

Query: 14  IRDSRQMVWVLSGNSLIAAPLSRSI---KPVTLHLIACRDTEFSDKEKGNMVYLGIKGKD 70
           +RDS+Q   V+SG   + A   +     + V   +   +  E +DK     V LG+K K+
Sbjct: 126 LRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIP---VALGLKEKN 182

Query: 71  LCLFCAEIQGKPTLQLK 87
           L L C     KPTLQL+
Sbjct: 183 LYLSCVLKDDKPTLQLE 199


>gi|76096366 phospholipase B1 [Homo sapiens]
          Length = 1458

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 17/48 (35%), Positives = 23/48 (47%), Gaps = 5/48 (10%)

Query: 50  DTEFSDKEKGNMVYLGIKGKDLCLFCAEIQGKPTLQLKLQGSQDNIGK 97
           DT    +E   ++ L I G DLC FC ++     +    Q   DNIGK
Sbjct: 494 DTRIHFQEDWKIITLFIGGNDLCDFCNDL-----VHYSPQNFTDNIGK 536


>gi|41462397 RAN guanine nucleotide release factor [Homo sapiens]
          Length = 186

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 15/35 (42%), Positives = 19/35 (54%)

Query: 10  KSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLH 44
           ++ A+R   Q  WVLSG   IA    +  K VTLH
Sbjct: 91  ENLALRGRCQEAWVLSGKQQIAKENQQVAKDVTLH 125


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,563,709
Number of Sequences: 37866
Number of extensions: 282419
Number of successful extensions: 417
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 401
Number of HSP's gapped (non-prelim): 17
length of query: 164
length of database: 18,247,518
effective HSP length: 94
effective length of query: 70
effective length of database: 14,688,114
effective search space: 1028167980
effective search space used: 1028167980
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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