Search of human proteins with 197927207

Search of human proteins with 197927207

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197927207 crystallin, zeta isoform c [Homo sapiens]
         (192 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197927207 crystallin, zeta isoform c [Homo sapiens]                375   e-104
gi|194239674 crystallin, zeta isoform a [Homo sapiens]                367   e-102
gi|13236495 crystallin, zeta isoform a [Homo sapiens]                 367   e-102
gi|194239676 crystallin, zeta isoform b [Homo sapiens]                286   7e-78
gi|18379349 vesicle amine transport protein 1 [Homo sapiens]           79   3e-15
gi|24308257 vesicle amine transport protein 1 homolog (T. califo...    75   4e-14
gi|41872631 fatty acid synthase [Homo sapiens]                         69   3e-12
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]       69   3e-12
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]       69   3e-12
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]        57   1e-08
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]        57   1e-08
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]        57   1e-08
gi|28557745 zinc binding alcohol dehydrogenase domain containing...    46   2e-05
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa...    44   8e-05
gi|156627571 sorbitol dehydrogenase [Homo sapiens]                     39   0.004
gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens]           33   0.11 
gi|90669511 crystallin, zeta-like 1 [Homo sapiens]                     32   0.43 
gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens]        31   0.57 
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b...    31   0.74 
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a...    31   0.74 
gi|40538880 aquaporin 12A [Homo sapiens]                               30   1.6  
gi|10863929 ribonuclease L [Homo sapiens]                              28   3.7  
gi|7705925 dicarbonyl/L-xylulose reductase [Homo sapiens]              28   4.8  

>gi|197927207 crystallin, zeta isoform c [Homo sapiens]
          Length = 192

 Score =  375 bits (963), Expect = e-104
 Identities = 192/192 (100%), Positives = 192/192 (100%)

Query: 1   MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV 60
           MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV
Sbjct: 1   MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV 60

Query: 61  FNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPR 120
           FNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPR
Sbjct: 61  FNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPR 120

Query: 121 DTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIH 180
           DTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIH
Sbjct: 121 DTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIH 180

Query: 181 GSGATGKMILLL 192
           GSGATGKMILLL
Sbjct: 181 GSGATGKMILLL 192


>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score =  367 bits (943), Expect = e-102
 Identities = 188/190 (98%), Positives = 189/190 (99%)

Query: 3   LLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 62
           L+ SACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN
Sbjct: 140 LIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 199

Query: 63  HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDT 122
           HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDT
Sbjct: 200 HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDT 259

Query: 123 MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS 182
           MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS
Sbjct: 260 MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS 319

Query: 183 GATGKMILLL 192
           GATGKMILLL
Sbjct: 320 GATGKMILLL 329


>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score =  367 bits (943), Expect = e-102
 Identities = 188/190 (98%), Positives = 189/190 (99%)

Query: 3   LLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 62
           L+ SACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN
Sbjct: 140 LIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 199

Query: 63  HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDT 122
           HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDT
Sbjct: 200 HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDT 259

Query: 123 MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS 182
           MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS
Sbjct: 260 MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS 319

Query: 183 GATGKMILLL 192
           GATGKMILLL
Sbjct: 320 GATGKMILLL 329


>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
          Length = 295

 Score =  286 bits (732), Expect = 7e-78
 Identities = 154/190 (81%), Positives = 155/190 (81%), Gaps = 34/190 (17%)

Query: 3   LLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 62
           L+ SACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN
Sbjct: 140 LIHSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 199

Query: 63  HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDT 122
           HREVNYIDKIK                                  VVGSRGTIEINPRDT
Sbjct: 200 HREVNYIDKIK----------------------------------VVGSRGTIEINPRDT 225

Query: 123 MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS 182
           MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS
Sbjct: 226 MAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENIIHGS 285

Query: 183 GATGKMILLL 192
           GATGKMILLL
Sbjct: 286 GATGKMILLL 295


>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
          Length = 393

 Score = 78.6 bits (192), Expect = 3e-15
 Identities = 61/212 (28%), Positives = 102/212 (48%), Gaps = 24/212 (11%)

Query: 1   MHLLSSACVKAGESVLVHGASGGVGLAACQIARAY-GLKILGTAGTEEGQKIVLQNGAHE 59
           M L     ++ G SVLVH A+GGVG+AA Q+ R    + + GTA   +  + + +NG   
Sbjct: 178 MVLFDFGNLQPGHSVLVHMAAGGVGMAAVQLCRTVENVTVFGTASASK-HEALKENGVTH 236

Query: 60  VFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINP 119
             ++   +Y+D+IKK +  KG+DI+++ L   + +K  +LL   G+V+  G    +    
Sbjct: 237 PIDYHTTDYVDEIKK-ISPKGVDIVMDPLGGSDTAKGYNLLKPMGKVVTYGMANLLTGPK 295

Query: 120 RDTMA------KESSIIGVTLFSSTK--------------EEFQQYAAALQAGMEIGWLK 159
           R+ MA       + S+  + L  + +              E      A L A    G +K
Sbjct: 296 RNLMALARTWWNQFSVTALQLLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIK 355

Query: 160 PVIGSQYPLEKVAEAHENIIHGSGATGKMILL 191
           P I S +P EKVA+A + +       GK++L+
Sbjct: 356 PHIDSVWPFEKVADAMKQMQEKKN-VGKVLLV 386


>gi|24308257 vesicle amine transport protein 1 homolog (T.
           californica)-like [Homo sapiens]
          Length = 419

 Score = 74.7 bits (182), Expect = 4e-14
 Identities = 66/215 (30%), Positives = 103/215 (47%), Gaps = 35/215 (16%)

Query: 3   LLSSACVKAGESVLVHGASGGVGLAACQIARAY-GLKILGTAGTEEGQKIVLQNGAHEVF 61
           L   A ++ G SVLVH A GGVG A  Q+      + + GTA T + + I  ++    +F
Sbjct: 172 LFEVANLREGMSVLVHSAGGGVGQAVAQLCSTVPNVTVFGTASTFKHEAI--KDSVTHLF 229

Query: 62  NHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTI------ 115
           + R  +Y+ ++K+ +  +G+DI+++ L   N  K LSLL   G  I+ GS   +      
Sbjct: 230 D-RNADYVQEVKR-ISAEGVDIVLDCLCGDNTGKGLSLLKPLGTYILYGSSNMVTGETKS 287

Query: 116 ------------EINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGME---IGW--- 157
                       ++NP     +   I G +L +     F+Q  A L  G+    IG    
Sbjct: 288 FFSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLL---FKQGRAGLIRGVVEKLIGLYNQ 344

Query: 158 --LKPVIGSQYPLEKVAEAHENIIHGSGATGKMIL 190
             +KPV+ S + LE+V EA +  IH  G  GK+IL
Sbjct: 345 KKIKPVVDSLWALEEVKEAMQR-IHDRGNIGKLIL 378


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 49/191 (25%), Positives = 95/191 (49%), Gaps = 10/191 (5%)

Query: 9    VKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVL----QNGAHEVFNHR 64
            V+ GE++L+H  SGGVG AA  IA + G ++  T G+ E +  +     Q  +    N R
Sbjct: 1665 VRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSR 1724

Query: 65   EVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINP--RDT 122
            + ++   +  + G KG+D+++  LA   L   +  L+  GR + +G     + +P     
Sbjct: 1725 DTSFEQHVLWHTGGKGVDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAI 1784

Query: 123  MAKESSIIGVTL---FSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAHENII 179
              K  +  GV L   F+ +  ++++  A +QAG+  G ++P+  + +   +V +A   + 
Sbjct: 1785 FLKNVTFHGVLLDAFFNESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEDAFRYMA 1844

Query: 180  HGSGATGKMIL 190
             G    GK+++
Sbjct: 1845 QGK-HIGKVVV 1854


>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 54/202 (26%), Positives = 101/202 (50%), Gaps = 13/202 (6%)

Query: 1   MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV 60
           +HL+ +  V+AG+ VL+H    GVG AA Q+ R  G   L TAG+++  ++  + GA   
Sbjct: 132 LHLVGN--VQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189

Query: 61  FNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINP- 119
           FN+++ ++ +   K+    G+++I++ +      K+++ L+  GR ++ G  G  +IN  
Sbjct: 190 FNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGP 249

Query: 120 --RDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-------LKPVIGSQYPLEK 170
                + K  S+I   L S   +  Q    A    +   +       L PV+   YP+ +
Sbjct: 250 LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTE 309

Query: 171 VAEAHENIIHGSGATGKMILLL 192
           + EAH+  +  +   GK++L L
Sbjct: 310 IQEAHK-YMEANKNIGKIVLEL 330


>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 54/202 (26%), Positives = 101/202 (50%), Gaps = 13/202 (6%)

Query: 1   MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV 60
           +HL+ +  V+AG+ VL+H    GVG AA Q+ R  G   L TAG+++  ++  + GA   
Sbjct: 132 LHLVGN--VQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189

Query: 61  FNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINP- 119
           FN+++ ++ +   K+    G+++I++ +      K+++ L+  GR ++ G  G  +IN  
Sbjct: 190 FNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGP 249

Query: 120 --RDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW-------LKPVIGSQYPLEK 170
                + K  S+I   L S   +  Q    A    +   +       L PV+   YP+ +
Sbjct: 250 LFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTE 309

Query: 171 VAEAHENIIHGSGATGKMILLL 192
           + EAH+  +  +   GK++L L
Sbjct: 310 IQEAHK-YMEANKNIGKIVLEL 330


>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 32/112 (28%), Positives = 56/112 (50%)

Query: 3   LLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 62
           LL    VK GE+V+V+ A+G VG    QIA+  G K++G  G++E    + + G   VFN
Sbjct: 133 LLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLGFDVVFN 192

Query: 63  HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGT 114
           ++ V  +++  K     G D   + +     +  +  +   GR+ + G+  T
Sbjct: 193 YKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIST 244


>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 32/112 (28%), Positives = 56/112 (50%)

Query: 3   LLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 62
           LL    VK GE+V+V+ A+G VG    QIA+  G K++G  G++E    + + G   VFN
Sbjct: 133 LLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLGFDVVFN 192

Query: 63  HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGT 114
           ++ V  +++  K     G D   + +     +  +  +   GR+ + G+  T
Sbjct: 193 YKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIST 244


>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
          Length = 301

 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 32/112 (28%), Positives = 56/112 (50%)

Query: 3   LLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFN 62
           LL    VK GE+V+V+ A+G VG    QIA+  G K++G  G++E    + + G   VFN
Sbjct: 133 LLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVGSDEKVAYLQKLGFDVVFN 192

Query: 63  HREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGT 114
           ++ V  +++  K     G D   + +     +  +  +   GR+ + G+  T
Sbjct: 193 YKTVESLEETLKKASPDGYDCYFDNVGGEFSNTVIGQMKKFGRIAICGAIST 244


>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
           [Homo sapiens]
          Length = 377

 Score = 45.8 bits (107), Expect = 2e-05
 Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 1/99 (1%)

Query: 12  GESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDK 71
           G+ VLV  A+GG G  A Q+++     ++GT  ++E    +   G     N++    +  
Sbjct: 173 GKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYK-TEPVGT 231

Query: 72  IKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVG 110
           + K    +G+D++ E +        +  L+  GR+IV+G
Sbjct: 232 VLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIG 270


>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
           sapiens]
          Length = 396

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 45/195 (23%), Positives = 91/195 (46%), Gaps = 22/195 (11%)

Query: 12  GESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEVFNHREVNYIDK 71
           G+ VL+ GASGGVG  A Q+ +A+   +     +++  ++V + GA +V +++  +  ++
Sbjct: 205 GKRVLILGASGGVGTFAIQVMKAWDAHVTAVC-SQDASELVRKLGADDVIDYKSGSVEEQ 263

Query: 72  IKKYVGEKGIDIIIEML--ANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMAKESSI 129
           +K     K  D I++ +  +    + D      G   + + +   + ++ R  +A     
Sbjct: 264 LKSL---KPFDFILDNVGGSTETWAPDFLKKWSGATYVTLVTPFLLNMD-RLGIADGMLQ 319

Query: 130 IGVTLFSSTKEEF-----QQYAAALQAG---------MEIGWLKPVIGSQYPLEKVAEAH 175
            GVT+ S   + F      ++A  + +G         ++ G ++PVI   +P  KV EA 
Sbjct: 320 TGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAF 379

Query: 176 ENIIHGSGATGKMIL 190
             +  G  A GK ++
Sbjct: 380 LKVERGH-ARGKTVI 393


>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
          Length = 357

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 47/188 (25%), Positives = 82/188 (43%), Gaps = 11/188 (5%)

Query: 1   MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGL-KILGTAGTEEGQKIVLQNGAHE 59
           +H      V  G  VLV GA G +G+    +A+A G  +++ T  +        + GA  
Sbjct: 162 IHACRRGGVTLGHKVLVCGA-GPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADL 220

Query: 60  VFNHREVNYIDKIKKYVGEKGI--DIIIEML-ANVNLSKDLSLLSHGGRVIVVGSRGTIE 116
           V    + +  +  +K  G+ G   ++ IE   A  ++   +     GG +++VG    + 
Sbjct: 221 VLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGNLVLVGLGSEMT 280

Query: 117 INPRDTMA-KESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPLEKVAEAH 175
             P    A +E  I GV  + +T       A ++ A   +  +KP++  ++PLEK  EA 
Sbjct: 281 TVPLLHAAIREVDIKGVFRYCNT----WPVAISMLASKSVN-VKPLVTHRFPLEKALEAF 335

Query: 176 ENIIHGSG 183
           E    G G
Sbjct: 336 ETFKKGLG 343


>gi|40807363 epidermal retinal dehydrogenase 2 [Homo sapiens]
          Length = 309

 Score = 33.5 bits (75), Expect = 0.11
 Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 12/83 (14%)

Query: 11  AGESVLVHGASGGVG-LAACQIARAYGLKIL---GTAGTEEGQKIVLQNGAHEVF----- 61
           AGE VL+ GA  G+G L A Q AR   + +L      G EE  K+  + GA  V      
Sbjct: 39  AGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCD 98

Query: 62  -NHREVNY--IDKIKKYVGEKGI 81
            + +E  Y   D++KK VG+  I
Sbjct: 99  CSQKEGVYRVADQVKKEVGDVSI 121


>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
          Length = 349

 Score = 31.6 bits (70), Expect = 0.43
 Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 17/121 (14%)

Query: 1   MHLLSSACVKAGESVLVHGASGGVGLAACQIARAYGLKILGTAGTEEGQKIVLQNGAHEV 60
           +H LS   +  G+SVL+   +   G  A Q+A   G K++ TA + E  K  L+     +
Sbjct: 136 LHYLSH--LSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLE-DKQCLERFRPPI 192

Query: 61  -----FNHREVNYIDKIKKYVGEKGIDIIIEMLANVNL-SKD------LSLLSHGGRVIV 108
                 ++ +V+  +   +  G  G+DI+++  A V L SKD      L LL H   +I 
Sbjct: 193 ARVIDVSNGKVHVAESCLEETGGLGVDIVLD--AGVRLYSKDDEPAVKLQLLPHKHDIIT 250

Query: 109 V 109
           +
Sbjct: 251 L 251


>gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens]
          Length = 260

 Score = 31.2 bits (69), Expect = 0.57
 Identities = 15/30 (50%), Positives = 19/30 (63%)

Query: 16 LVHGASGGVGLAACQIARAYGLKILGTAGT 45
          LV GASGG+G A  +     GLK++G A T
Sbjct: 15 LVTGASGGIGAAVARALVQQGLKVVGCART 44


>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
           [Homo sapiens]
          Length = 297

 Score = 30.8 bits (68), Expect = 0.74
 Identities = 29/130 (22%), Positives = 56/130 (43%), Gaps = 15/130 (11%)

Query: 9   VKAGESVLVHGASGGVGLAACQIARAYGLKILGTA-GTEEGQKI---VLQNGAHEVFNHR 64
           ++ G+SV+ + ++ GVG A  QIA A GL+ +       + QK+   +   GA  V    
Sbjct: 105 LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE 164

Query: 65  EVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMA 124
           E+   +    +       + +  +   + ++ L  L+ GG ++  G            MA
Sbjct: 165 ELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGG-----------MA 213

Query: 125 KESSIIGVTL 134
           K+  +  V+L
Sbjct: 214 KQPVVASVSL 223


>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
           [Homo sapiens]
          Length = 373

 Score = 30.8 bits (68), Expect = 0.74
 Identities = 29/130 (22%), Positives = 56/130 (43%), Gaps = 15/130 (11%)

Query: 9   VKAGESVLVHGASGGVGLAACQIARAYGLKILGTA-GTEEGQKI---VLQNGAHEVFNHR 64
           ++ G+SV+ + ++ GVG A  QIA A GL+ +       + QK+   +   GA  V    
Sbjct: 181 LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE 240

Query: 65  EVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVVGSRGTIEINPRDTMA 124
           E+   +    +       + +  +   + ++ L  L+ GG ++  G            MA
Sbjct: 241 ELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGG-----------MA 289

Query: 125 KESSIIGVTL 134
           K+  +  V+L
Sbjct: 290 KQPVVASVSL 299


>gi|40538880 aquaporin 12A [Homo sapiens]
          Length = 295

 Score = 29.6 bits (65), Expect = 1.6
 Identities = 26/108 (24%), Positives = 50/108 (46%), Gaps = 12/108 (11%)

Query: 50  KIVLQNGAHEVFNHREVNYIDKIKKYVGEKGIDIIIEMLANVNLSKDLSLLSHGGRVIVV 109
           K +L  GA+EVF    +  + ++  + G+ G D+++ +L        L  L+HG  V + 
Sbjct: 26  KALLPVGAYEVFAREAMRTLVELGPWAGDFGPDLLLTLLF-------LLFLAHG--VTLD 76

Query: 110 GSRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGW 157
           G+     ++ ++ +  E S+ G  L  + +    Q A  L   M + W
Sbjct: 77  GASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTL---MRLCW 121


>gi|10863929 ribonuclease L [Homo sapiens]
          Length = 741

 Score = 28.5 bits (62), Expect = 3.7
 Identities = 33/115 (28%), Positives = 46/115 (40%), Gaps = 26/115 (22%)

Query: 25  GLAACQIARAYG----LKILGTAG--------TEEGQKIVLQNGAHEVFNHREVNYIDKI 72
           G  A   A  YG    LK L   G        T+E Q+ + + GA  + +  E  +++ +
Sbjct: 125 GFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVL 184

Query: 73  KKYVGEKGIDIII------EMLANVNLSKDLS--------LLSHGGRVIVVGSRG 113
           K  + E G D+          L +  LS D S        LL HG  V V G RG
Sbjct: 185 KILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERG 239


>gi|7705925 dicarbonyl/L-xylulose reductase [Homo sapiens]
          Length = 244

 Score = 28.1 bits (61), Expect = 4.8
 Identities = 13/36 (36%), Positives = 19/36 (52%)

Query: 11 AGESVLVHGASGGVGLAACQIARAYGLKILGTAGTE 46
          AG  VLV GA  G+G    Q   A G +++  + T+
Sbjct: 6  AGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQ 41


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,309,973
Number of Sequences: 37866
Number of extensions: 240660
Number of successful extensions: 567
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 539
Number of HSP's gapped (non-prelim): 25
length of query: 192
length of database: 18,247,518
effective HSP length: 97
effective length of query: 95
effective length of database: 14,574,516
effective search space: 1384579020
effective search space used: 1384579020
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.