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Search of human proteins with 19718780
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19718780 semaphorin 6B precursor [Homo sapiens]
(888 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19718780 semaphorin 6B precursor [Homo sapiens] 1830 0.0
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 733 0.0
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 638 0.0
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 632 0.0
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 631 0.0
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 611 e-175
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 608 e-174
gi|16306552 semaphorin Y [Homo sapiens] 550 e-156
gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] 523 e-148
gi|147904700 semaphorin 5A [Homo sapiens] 302 8e-82
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 289 9e-78
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 266 8e-71
gi|39777610 semaphorin 4B precursor [Homo sapiens] 263 7e-70
gi|39777608 semaphorin 4B precursor [Homo sapiens] 263 7e-70
gi|5174673 semaphorin 3A precursor [Homo sapiens] 263 7e-70
gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] 261 2e-69
gi|6912650 semaphorin 3E [Homo sapiens] 256 9e-68
gi|9910362 semaphorin sem2 [Homo sapiens] 246 7e-65
gi|41406086 semaphorin 3D [Homo sapiens] 246 9e-65
gi|21361914 semaphorin B [Homo sapiens] 241 3e-63
gi|5454048 semaphorin 3C [Homo sapiens] 240 4e-63
gi|188497703 semaphorin 3F [Homo sapiens] 237 4e-62
gi|157388902 semaphorin 4C [Homo sapiens] 236 5e-62
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 234 2e-61
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 234 2e-61
gi|19923279 semaphorin W [Homo sapiens] 234 3e-61
gi|28872814 semaphorin 4G [Homo sapiens] 212 1e-54
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 123 7e-28
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 122 2e-27
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 99 2e-20
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 1830 bits (4740), Expect = 0.0
Identities = 888/888 (100%), Positives = 888/888 (100%)
Query: 1 MQTPRASPPRPALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAE 60
MQTPRASPPRPALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAE
Sbjct: 1 MQTPRASPPRPALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAE 60
Query: 61 GADDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKG 120
GADDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKG
Sbjct: 61 GADDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKG 120
Query: 121 KQEGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKH 180
KQEGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKH
Sbjct: 121 KQEGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKH 180
Query: 181 ANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSH 240
ANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSH
Sbjct: 181 ANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSH 240
Query: 241 VYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHF 300
VYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHF
Sbjct: 241 VYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHF 300
Query: 301 YFNVLQAVTGVVSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPES 360
YFNVLQAVTGVVSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPES
Sbjct: 301 YFNVLQAVTGVVSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPES 360
Query: 361 IWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILR 420
IWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILR
Sbjct: 361 IWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILR 420
Query: 421 TLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFET 480
TLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFET
Sbjct: 421 TLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFET 480
Query: 481 YRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQ 540
YRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQ
Sbjct: 481 YRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQ 540
Query: 541 DPYCGWAPDGSCIFLSPGTRAAFEQDVSGASTSGLGDCTGLLRASLSEDRAGLVSVNLLV 600
DPYCGWAPDGSCIFLSPGTRAAFEQDVSGASTSGLGDCTGLLRASLSEDRAGLVSVNLLV
Sbjct: 541 DPYCGWAPDGSCIFLSPGTRAAFEQDVSGASTSGLGDCTGLLRASLSEDRAGLVSVNLLV 600
Query: 601 TSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVSRLGERRAQ 660
TSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVSRLGERRAQ
Sbjct: 601 TSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVSRLGERRAQ 660
Query: 661 GPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDLDSGLLPTPEQTPLPQKRL 720
GPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDLDSGLLPTPEQTPLPQKRL
Sbjct: 661 GPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDLDSGLLPTPEQTPLPQKRL 720
Query: 721 PTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQPPAPGEPTPDGRLYAARPG 780
PTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQPPAPGEPTPDGRLYAARPG
Sbjct: 721 PTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQPPAPGEPTPDGRLYAARPG 780
Query: 781 RASHGDFPLTPHASPDRRRVVSAPTGPLDPASAADGLPRPWSPPPTGSLRRPLGPHAPPA 840
RASHGDFPLTPHASPDRRRVVSAPTGPLDPASAADGLPRPWSPPPTGSLRRPLGPHAPPA
Sbjct: 781 RASHGDFPLTPHASPDRRRVVSAPTGPLDPASAADGLPRPWSPPPTGSLRRPLGPHAPPA 840
Query: 841 ATLRRTHTFNSGEARPGDRHRGCHARPGTDLAHLLPYGGADRTAPPVP 888
ATLRRTHTFNSGEARPGDRHRGCHARPGTDLAHLLPYGGADRTAPPVP
Sbjct: 841 ATLRRTHTFNSGEARPGDRHRGCHARPGTDLAHLLPYGGADRTAPPVP 888
>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
domain, (semaphorin) 6A [Homo sapiens]
Length = 1030
Score = 733 bits (1892), Expect = 0.0
Identities = 393/809 (48%), Positives = 512/809 (63%), Gaps = 103/809 (12%)
Query: 12 ALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71
ALLL LL A FPE+ P+S++ +Y YPVFVG PGR T L+IQ ++
Sbjct: 5 ALLLYFTLLHFAGAGFPEDSEPISISHGNYTKQYPVFVGHKPGRNTTQRHR--LDIQMIM 62
Query: 72 RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVK 131
+N TL+I RD++Y V+++ + E+ +KLTW+S +D++ CRMKGK + EC NF+K
Sbjct: 63 IMNGTLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFIK 122
Query: 132 VLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGML 191
VLL +++ LFVCG+NAFNP C NY +DTL+P GD SGMARCPYD KHANVALF+DG L
Sbjct: 123 VLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHANVALFADGKL 182
Query: 192 FTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAME 251
++ATVTDFLAIDAVIYRSLG+ PTLRTVKHDSKW KEPYFV AV++G ++YFFFREIA+E
Sbjct: 183 YSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVE 242
Query: 252 FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGV 311
+N + KVV RVA+VCKND+GGS RVLEKQWTSFLKARLNCSVPGDSHFYFN+LQAVT V
Sbjct: 243 YNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDV 302
Query: 312 VSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVP 371
+ + GR VVLA FSTP NSIPGSAVCA+D+ +A+VF GRF+EQKSP+S WTPVP+++VP
Sbjct: 303 IRINGRDVVLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVPDERVP 362
Query: 372 RPRPGCCAAPGM--QYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTR 429
+PRPGCCA +Y S+ PDD LNF+KTHPLMDEAVPS+ + PW LRT++R++LT+
Sbjct: 363 KPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMVRYRLTK 422
Query: 430 VAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRP 489
+AVD AGP+ N TVVFLGSE G +LKFL R SG S+FLEE Y ++C
Sbjct: 423 IAVDTAAGPYQNHTVVFLGSEKGIILKFLAR--IGNSGFLNDSLFLEEMSVYNSEKCSYD 480
Query: 490 GGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPD 549
G + +R++ ++LD AS L AF CV++VP+ RC+++ C K CI S+DPYCGW +
Sbjct: 481 GVED--KRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGWIKE 538
Query: 550 -GSCIFLSPGTRAAFEQDVSGASTSGLGDC------------------------------ 578
G+C LSP +R FEQD+ +T GLGDC
Sbjct: 539 GGACSHLSPNSRLTFEQDIERGNTDGLGDCHNSFVALNGHSSSLLPSTTTSDSTAQEGYE 598
Query: 579 --------------------TGLLRASLSEDRAGLVSVNLL--------VTSSVAAFVV- 609
G + + +D+ G++ + L VT A ++
Sbjct: 599 SRGGMLDWKHLLDSPDSTDPLGAVSSHNHQDKKGVIRESYLKGHDQLVPVTLLAIAVILA 658
Query: 610 ---GAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVSRL----GERRAQGP 662
GAV SG +V + V R+++A + KE L H ++ SV++L G+ +++ P
Sbjct: 659 FVMGAVFSGITV-YCVCDHRRKDVAVVQRKEKELTHSRRGSMSSVTKLSGLFGDTQSKDP 717
Query: 663 GGRGGGGGGGAGVPPEALLAPLMQNGW------AKATLLQGGPHDLDSGLLPTPEQTP-L 715
PEA+L PLM NG L++ H LD LPTPE TP L
Sbjct: 718 -------------KPEAILTPLMHNGKLATPGNTAKMLIKADQHHLDLTALPTPESTPTL 764
Query: 716 PQKRLPTPHPHPHALGPRAWDHGHPLLPA 744
QKR P + G R W+ L+ A
Sbjct: 765 QQKRKP-------SRGSREWERNQNLINA 786
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 638 bits (1646), Expect = 0.0
Identities = 347/780 (44%), Positives = 472/780 (60%), Gaps = 49/780 (6%)
Query: 12 ALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71
A +LLL++ FPE+ PL+ Y YPVF G G E L+ Q +L
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGN----ESQHRLDFQLML 63
Query: 72 RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVK 131
++ TL+I RD +Y V L TE+ +KLTWRS D C MKGK + EC NF+K
Sbjct: 64 KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIK 123
Query: 132 VLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGML 191
V + R++ +FVCG+NAFNP+C Y + TL+ G+ ISG+ARCP+D + NVALF+DG L
Sbjct: 124 VFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKL 183
Query: 192 FTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAME 251
++ATV DFLA DAVIYRS+GD LRT+K+DSKW KEP+F+HA+E+G++VYFFFREIA+E
Sbjct: 184 YSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVE 243
Query: 252 FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGV 311
N L K V SRVAR+CKND+GGS RVLEK WTSFLKARLNCSVPGDS FYF+VLQ++T +
Sbjct: 244 HNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDI 303
Query: 312 VSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVP 371
+ + G P V+ VF+T NSIPGSAVCAF + + VF+GRF+EQK+P+S+WT VPED+VP
Sbjct: 304 IQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVP 363
Query: 372 RPRPGCCAAPGM--QYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTR 429
+PRPGCCA G+ Y S PD+ L+F+K+HPLMD AVP + PW +T +R++LT
Sbjct: 364 KPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTA 423
Query: 430 VAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRP 489
++VD AGP+ N TV+F+GSEAG VLK L + + + SV LEE E Y +C
Sbjct: 424 ISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND---SVLLEEIEAYNHAKCS-- 478
Query: 490 GGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPD 549
E ++++SL+LD L AF C++R+P++RC++Y C K+CI S+DPYCGW
Sbjct: 479 AENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ 538
Query: 550 GSCIFLSPGTRA-AFEQDVSGASTSGLGDCTGLLRASLSEDRAGLVSVNLLVTSSVAAFV 608
GSC ++PG A +EQD +T+ LGDC G+ S + +V +N+L+T AAFV
Sbjct: 539 GSCGRVTPGMLAEGYEQDTEFGNTAHLGDCHGVRWEVQSGESNQMVHMNVLITCVFAAFV 598
Query: 609 VGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVSRLG----------ERR 658
+GA ++G +V + + R+ KD E+ A ++ S ++L ++
Sbjct: 599 LGAFIAGVAVYCYRDMFVRKNRKIHKDAES--AQSCTDSSGSFAKLNGLFDSPVKEYQQN 656
Query: 659 AQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDLDSGLLPTPEQTP-LPQ 717
P +PP NG K+ ++ + LPTPE TP L Q
Sbjct: 657 IDSPKLYSNLLTSRKELPP---------NGDTKSMVMDHRGQPPELAALPTPESTPVLHQ 707
Query: 718 KRLPTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQPPAPGEPTPDGRLYAA 777
K L H HGH AS + P P PP P P G + +A
Sbjct: 708 KTLQAMKSHSEKA------HGH---GASRKET-----PQFFPSSPP-PHSPLSHGHIPSA 752
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 632 bits (1631), Expect = 0.0
Identities = 346/793 (43%), Positives = 472/793 (59%), Gaps = 62/793 (7%)
Query: 12 ALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71
A +LLL++ FPE+ PL+ Y YPVF G G E L+ Q +L
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGN----ESQHRLDFQLML 63
Query: 72 RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVK 131
++ TL+I RD +Y V L TE+ +KLTWRS D C MKGK + EC NF+K
Sbjct: 64 KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIK 123
Query: 132 VLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGML 191
V + R++ +FVCG+NAFNP+C Y + TL+ G+ ISG+ARCP+D + NVALF+DG L
Sbjct: 124 VFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKL 183
Query: 192 FTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAME 251
++ATV DFLA DAVIYRS+GD LRT+K+DSKW KEP+F+HA+E+G++VYFFFREIA+E
Sbjct: 184 YSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVE 243
Query: 252 FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGV 311
N L K V SRVAR+CKND+GGS RVLEK WTSFLKARLNCSVPGDS FYF+VLQ++T +
Sbjct: 244 HNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDI 303
Query: 312 VSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVP 371
+ + G P V+ VF+T NSIPGSAVCAF + + VF+GRF+EQK+P+S+WT VPED+VP
Sbjct: 304 IQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVP 363
Query: 372 RPRPGCCAAPGM--QYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTR 429
+PRPGCCA G+ Y S PD+ L+F+K+HPLMD AVP + PW +T +R++LT
Sbjct: 364 KPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTA 423
Query: 430 VAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRP 489
++VD AGP+ N TV+F+GSEAG VLK L + + + SV LEE E Y +C
Sbjct: 424 ISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND---SVLLEEIEAYNHAKCS-- 478
Query: 490 GGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPD 549
E ++++SL+LD L AF C++R+P++RC++Y C K+CI S+DPYCGW
Sbjct: 479 AENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ 538
Query: 550 GSCIFLSPG--------------TRAAFEQDVSGASTSGLGDCTGLLRASLSEDRAGLVS 595
GSC ++PG + +EQD +T+ LGDC G+ S + +V
Sbjct: 539 GSCGRVTPGMLLLTEDFFAFHNHSAEGYEQDTEFGNTAHLGDCHGVRWEVQSGESNQMVH 598
Query: 596 VNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVSRLG 655
+N+L+T AAFV+GA ++G +V + + R+ KD E+ A ++ S ++L
Sbjct: 599 MNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAES--AQSCTDSSGSFAKLN 656
Query: 656 ----------ERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDLDSG 705
++ P +PP NG K+ ++ +
Sbjct: 657 GLFDSPVKEYQQNIDSPKLYSNLLTSRKELPP---------NGDTKSMVMDHRGQPPELA 707
Query: 706 LLPTPEQTP-LPQKRLPTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQPPA 764
LPTPE TP L QK L H HGH AS + P P PP
Sbjct: 708 ALPTPESTPVLHQKTLQAMKSHSEKA------HGH---GASRKET-----PQFFPSSPP- 752
Query: 765 PGEPTPDGRLYAA 777
P P G + +A
Sbjct: 753 PHSPLSHGHIPSA 765
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 631 bits (1628), Expect = 0.0
Identities = 349/799 (43%), Positives = 476/799 (59%), Gaps = 68/799 (8%)
Query: 12 ALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71
A +LLL++ FPE+ PL+ Y YPVF G G E L+ Q +L
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGN----ESQHRLDFQLML 63
Query: 72 RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVK 131
++ TL+I RD +Y V L TE+ +KLTWRS D C MKGK + EC NF+K
Sbjct: 64 KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIK 123
Query: 132 VLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGML 191
V + R++ +FVCG+NAFNP+C Y + TL+ G+ ISG+ARCP+D + NVALF+DG L
Sbjct: 124 VFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKL 183
Query: 192 FTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAME 251
++ATV DFLA DAVIYRS+GD LRT+K+DSKW KEP+F+HA+E+G++VYFFFREIA+E
Sbjct: 184 YSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVE 243
Query: 252 FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGV 311
N L K V SRVAR+CKND+GGS RVLEK WTSFLKARLNCSVPGDS FYF+VLQ++T +
Sbjct: 244 HNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDI 303
Query: 312 VSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVP 371
+ + G P V+ VF+T NSIPGSAVCAF + + VF+GRF+EQK+P+S+WT VPED+VP
Sbjct: 304 IQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVP 363
Query: 372 RPRPGCCAAPGM--QYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTR 429
+PRPGCCA G+ Y S PD+ L+F+K+HPLMD AVP + PW +T +R++LT
Sbjct: 364 KPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTA 423
Query: 430 VAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRP 489
++VD AGP+ N TV+F+GSEAG VLK L + + + SV LEE E Y +C
Sbjct: 424 ISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND---SVLLEEIEAYNHAKCS-- 478
Query: 490 GGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPD 549
E ++++SL+LD L AF C++R+P++RC++Y C K+CI S+DPYCGW
Sbjct: 479 AENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ 538
Query: 550 GSCIFLSPGTRA-AFEQDVSGASTSGLGDCTGLLRASLSED---------------RAG- 592
GSC ++PG A +EQD +T+ LGDC +L S + D ++G
Sbjct: 539 GSCGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPTSGVRWEVQSGE 598
Query: 593 ---LVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVL 649
+V +N+L+T AAFV+GA ++G +V + + R+ KD E+ A ++
Sbjct: 599 SNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAES--AQSCTDSSG 656
Query: 650 SVSRLG----------ERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGP 699
S ++L ++ P +PP NG K+ ++
Sbjct: 657 SFAKLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPP---------NGDTKSMVMDHRG 707
Query: 700 HDLDSGLLPTPEQTP-LPQKRLPTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARA 758
+ LPTPE TP L QK L H HGH AS + P
Sbjct: 708 QPPELAALPTPESTPVLHQKTLQAMKSHSEKA------HGH---GASRKET-----PQFF 753
Query: 759 PEQPPAPGEPTPDGRLYAA 777
P PP P P G + +A
Sbjct: 754 PSSPP-PHSPLSHGHIPSA 771
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 611 bits (1576), Expect = e-175
Identities = 298/581 (51%), Positives = 397/581 (68%), Gaps = 12/581 (2%)
Query: 12 ALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71
A +LLL++ FPE+ PL+ Y YPVF G G E L+ Q +L
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGN----ESQHRLDFQLML 63
Query: 72 RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVK 131
++ TL+I RD +Y V L TE+ +KLTWRS D C MKGK + EC NF+K
Sbjct: 64 KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIK 123
Query: 132 VLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGML 191
V + R++ +FVCG+NAFNP+C Y + TL+ G+ ISG+ARCP+D + NVALF+DG L
Sbjct: 124 VFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKL 183
Query: 192 FTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAME 251
++ATV DFLA DAVIYRS+GD LRT+K+DSKW KEP+F+HA+E+G++VYFFFREIA+E
Sbjct: 184 YSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVE 243
Query: 252 FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGV 311
N L K V SRVAR+CKND+GGS RVLEK WTSFLKARLNCSVPGDS FYF+VLQ++T +
Sbjct: 244 HNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDI 303
Query: 312 VSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVP 371
+ + G P V+ VF+T NSIPGSAVCAF + + VF+GRF+EQK+P+S+WT VPED+VP
Sbjct: 304 IQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVP 363
Query: 372 RPRPGCCAAPGM--QYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTR 429
+PRPGCCA G+ Y S PD+ L+F+K+HPLMD AVP + PW +T +R++LT
Sbjct: 364 KPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTA 423
Query: 430 VAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRP 489
++VD AGP+ N TV+F+GSEAG VLK L + + + SV LEE E Y +C
Sbjct: 424 ISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND---SVLLEEIEAYNHAKCS-- 478
Query: 490 GGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPD 549
E ++++SL+LD L AF C++R+P++RC++Y C K+CI S+DPYCGW
Sbjct: 479 AENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ 538
Query: 550 GSCIFLSPGTRA-AFEQDVSGASTSGLGDCTGLLRASLSED 589
GSC ++PG A +EQD +T+ LGDC +L S + D
Sbjct: 539 GSCGRVTPGMLAEGYEQDTEFGNTAHLGDCHEILPTSTTPD 579
Score = 37.4 bits (85), Expect = 0.062
Identities = 50/196 (25%), Positives = 76/196 (38%), Gaps = 37/196 (18%)
Query: 593 LVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAGEAVLSVS 652
+V +N+L+T AAFV+GA ++G +V + + R+ KD E+ A ++ S +
Sbjct: 658 MVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAES--AQSCTDSSGSFA 715
Query: 653 RLG----------ERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLLQGGPHDL 702
+L ++ P +PP NG K+ ++
Sbjct: 716 KLNGLFDSPVKEYQQNIDSPKLYSNLLTSRKELPP---------NGDTKSMVMDHRGQPP 766
Query: 703 DSGLLPTPEQTP-LPQKRLPTPHPHPHALGPRAWDHGHPLLPASASSSLLLLAPARAPEQ 761
+ LPTPE TP L QK L H HGH AS + P P
Sbjct: 767 ELAALPTPESTPVLHQKTLQAMKSHSEKA------HGH---GASRKET-----PQFFPSS 812
Query: 762 PPAPGEPTPDGRLYAA 777
PP P P G + +A
Sbjct: 813 PP-PHSPLSHGHIPSA 827
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 608 bits (1567), Expect = e-174
Identities = 295/570 (51%), Positives = 392/570 (68%), Gaps = 12/570 (2%)
Query: 12 ALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71
A +LLL++ FPE+ PL+ Y YPVF G G E L+ Q +L
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGN----ESQHRLDFQLML 63
Query: 72 RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVK 131
++ TL+I RD +Y V L TE+ +KLTWRS D C MKGK + EC NF+K
Sbjct: 64 KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIK 123
Query: 132 VLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGML 191
V + R++ +FVCG+NAFNP+C Y + TL+ G+ ISG+ARCP+D + NVALF+DG L
Sbjct: 124 VFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKL 183
Query: 192 FTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAME 251
++ATV DFLA DAVIYRS+GD LRT+K+DSKW KEP+F+HA+E+G++VYFFFREIA+E
Sbjct: 184 YSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVE 243
Query: 252 FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGV 311
N L K V SRVAR+CKND+GGS RVLEK WTSFLKARLNCSVPGDS FYF+VLQ++T +
Sbjct: 244 HNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDI 303
Query: 312 VSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVP 371
+ + G P V+ VF+T NSIPGSAVCAF + + VF+GRF+EQK+P+S+WT VPED+VP
Sbjct: 304 IQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVP 363
Query: 372 RPRPGCCAAPGM--QYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTR 429
+PRPGCCA G+ Y S PD+ L+F+K+HPLMD AVP + PW +T +R++LT
Sbjct: 364 KPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTA 423
Query: 430 VAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRP 489
++VD AGP+ N TV+F+GSEAG VLK L + + + SV LEE E Y +C
Sbjct: 424 ISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND---SVLLEEIEAYNHAKCS-- 478
Query: 490 GGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPD 549
E ++++SL+LD L AF C++R+P++RC++Y C K+CI S+DPYCGW
Sbjct: 479 AENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKSCIASRDPYCGWLSQ 538
Query: 550 GSCIFLSPGTRA-AFEQDVSGASTSGLGDC 578
GSC ++PG A +EQD +T+ LGDC
Sbjct: 539 GSCGRVTPGMLAEGYEQDTEFGNTAHLGDC 568
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 550 bits (1416), Expect = e-156
Identities = 363/894 (40%), Positives = 471/894 (52%), Gaps = 81/894 (9%)
Query: 4 PRASPPRPALLLLLLL-LGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGA 62
PRA P LLLLLLL L FP++P PL ++ + F G + G
Sbjct: 2 PRAPHFMPLLLLLLLLSLPHTQAAFPQDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGL 61
Query: 63 DDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTE-LRYQRKLTWRSNPSDINVCRMKGK 121
D QR L +NRTL + RD+++ +L+ E L + LTWRS D+ C ++GK
Sbjct: 62 D---FQRFLTLNRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQ--DVENCAVRGK 116
Query: 122 QEGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHA 181
EC N+++VL+ D TL CG+N+F+PVC +Y I +LQ G+ +SG ARCP+D +
Sbjct: 117 LTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQARCPFDATQS 176
Query: 182 NVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHV 241
NVA+F++G L++AT DF A DAV+YRSLG +P LR+ K+DSKW +EP+FV A+E G HV
Sbjct: 177 NVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQALEHGDHV 236
Query: 242 YFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFY 301
YFFFRE+++E L +V SRVARVCK D+GGSPR L++ WTSFLK RLNCSVPGDS FY
Sbjct: 237 YFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFY 296
Query: 302 FNVLQAVTGVVSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESI 361
F+VLQA+TG V+L GR + VF+T +NSIPGSAVCAF L ++ FEG+F+EQ+S +
Sbjct: 297 FDVLQALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLDGA 356
Query: 362 WTPVPEDQVPRPRPGCCAAPG--MQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWIL 419
WTPV ED+VP PRPG CA G +++S LPDD+L F+K HPL+D AVP + H P +L
Sbjct: 357 WTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAVPPVTHQP-LL 415
Query: 420 RTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFE 479
R LT+VAVD AGP N TV+FLGS GTVLK L P + G + LEE +
Sbjct: 416 TLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLT-PGGRSGGPE--PILLEEID 472
Query: 480 TYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGS 539
Y P RC +T +R++ LELD L AF C+V +P++RC ++ C ++C+ S
Sbjct: 473 AYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLAS 532
Query: 540 QDPYCGWAPDGSCIFL---------SPGTRAAFE----QDVSGASTSGLGDCTGLLRASL 586
QDPYCGW C+ + G + + E QD + S SG GD +R L
Sbjct: 533 QDPYCGWHSSRGCVDIRGSGGTDVDQAGNQESMEHGDCQDGATGSQSGPGDSAYGVRRDL 592
Query: 587 SEDRAG-LVSVNLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKDKEAILAHGAG 645
A V + LL+ S AAF +GA VSG V RR R KD E
Sbjct: 593 PPASASRSVPIPLLLASVAAAFALGASVSGLLVSCACRRAHRR---RGKDIET-PGLPRP 648
Query: 646 EAVLSVSRLGERRAQGPGGRGGGGGGGAGVPPEALLAPLMQNGWAKATLL---QGGPHDL 702
++ S++RL GGG PP + +Q T L +G P
Sbjct: 649 LSLRSLARL--------------HGGGPEPPPPSKDGDAVQTPQLYTTFLPPPEGVPPP- 693
Query: 703 DSGLLPTPEQTP-LPQKRL-------------------PTPHPHPHALG---PRAW---- 735
+ LPTPE TP LP K L P HA G PR
Sbjct: 694 ELACLPTPESTPELPVKHLRAAGDPWEWNQNRNNAKEGPGRSRGGHAAGGPAPRVLVRPP 753
Query: 736 DHGHPLLPASASSSLLLLAPARAPEQPPAPGEPTP---DGRLYAARPGRASHGDFPLTPH 792
G P ++ LL P QPP G P R P A G PH
Sbjct: 754 PPGCPGQAVEVTTLEELLRYLHGP-QPPRKGAEPPAPLTSRALPPEPAPALLGGPSPRPH 812
Query: 793 ASPDRRRVVSAPTGPLDPASAADGLPRPWSPPPTGSLRR-PLGPHAPPAATLRR 845
R+ P G A A L P G RR P H P A L R
Sbjct: 813 ECASPLRLDVPPEGRCASAPARPALSAPAPRLGVGGGRRLPFSGHRAPPALLTR 866
>gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]
Length = 476
Score = 523 bits (1347), Expect = e-148
Identities = 255/472 (54%), Positives = 332/472 (70%), Gaps = 9/472 (1%)
Query: 12 ALLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTPAEGADDLNIQRVL 71
A +LLL++ FPE+ PL+ Y YPVF G G E L+ Q +L
Sbjct: 8 AYILLLMVSQLRAVSFPEDDEPLNTVDYHYSRQYPVFRGRPSGN----ESQHRLDFQLML 63
Query: 72 RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVK 131
++ TL+I RD +Y V L TE+ +KLTWRS D C MKGK + EC NF+K
Sbjct: 64 KIRDTLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHKDECHNFIK 123
Query: 132 VLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGML 191
V + R++ +FVCG+NAFNP+C Y + TL+ G+ ISG+ARCP+D + NVALF+DG L
Sbjct: 124 VFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTNVALFADGKL 183
Query: 192 FTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAME 251
++ATV DFLA DAVIYRS+GD LRT+K+DSKW KEP+F+HA+E+G++VYFFFREIA+E
Sbjct: 184 YSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYGNYVYFFFREIAVE 243
Query: 252 FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGV 311
N L K V SRVAR+CKND+GGS RVLEK WTSFLKARLNCSVPGDS FYF+VLQ++T +
Sbjct: 244 HNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFDVLQSITDI 303
Query: 312 VSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVP 371
+ + G P V+ VF+T NSIPGSAVCAF + + VF+GRF+EQK+P+S+WT VPED+VP
Sbjct: 304 IQINGIPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPEDKVP 363
Query: 372 RPRPGCCAAPGM--QYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTR 429
+PRPGCCA G+ Y S PD+ L+F+K+HPLMD AVP + PW +T +R++LT
Sbjct: 364 KPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTA 423
Query: 430 VAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETY 481
++VD AGP+ N TV+F+GSEAG VLK L + + + SV LEE E Y
Sbjct: 424 ISVDHSAGPYQNYTVIFVGSEAGMVLKVLAKTSPFSLND---SVLLEEIEAY 472
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 302 bits (774), Expect = 8e-82
Identities = 193/505 (38%), Positives = 271/505 (53%), Gaps = 39/505 (7%)
Query: 75 RTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGECRNFVKVLL 134
+ L +G R+ L+R++LE +L + + W + + C KGK + EC+N+++VLL
Sbjct: 68 KELVVGARNYLFRLQLE-----DLSLIQAVEWECDEATKKACYSKGKSKEECQNYIRVLL 122
Query: 135 LRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFS-DGMLFT 193
+ + LF CG+NAF PVC N S+ L + D ISGMARCPY P+H + AL + G L+
Sbjct: 123 VGGDR-LFTCGTNAFTPVCTNRSLSNLTEIHDQISGMARCPYSPQHNSTALLTAGGELYA 181
Query: 194 ATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGSHVYFFFREIAMEFN 253
AT DF D IYRSLG P LRT +++SKW EP FV + + G+ YFFFRE A+E +
Sbjct: 182 ATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLNEPNFVSSYDIGNFTYFFFRENAVEHD 241
Query: 254 YLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVS 313
K V SR ARVCKND+GG +LE WT+F+KARLNCS PG+ FY+N LQ+ +
Sbjct: 242 -CGKTVFSRAARVCKNDIGGR-FLLEDTWTTFMKARLNCSRPGEVPFYYNELQSTFFLPE 299
Query: 314 LGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRP 373
L ++ +F+T NSI SAVC F+L+ +A F G F+ Q++ S W P P P P
Sbjct: 300 L---DLIYGIFTTNVNSIAASAVCVFNLSAIAQAFSGPFKYQENSRSAWLPYPN---PNP 353
Query: 374 RPGC-CAAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTRVAV 432
C G+ N + D F+ LM E V + P + R + VAV
Sbjct: 354 HFQCGTVDQGLYVNLTERNLQDAQKFI----LMHEVVQPVTTVPSFMEDNSR--FSHVAV 407
Query: 433 DVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGG 492
DV G +++L ++ GT+ K V N ++S S LEE E + P+R P
Sbjct: 408 DVVQGREALVHIIYLATDYGTIKKVRVPLNQTSS-----SCLLEEIELF-PERRREP--- 458
Query: 493 ETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGW-APDGS 551
+ SL++ + L VV++P+ RCQ Y CIG+QDPYCGW
Sbjct: 459 -----IRSLQILHSQSVLFVGLREHVVKIPLKRCQFYR-TRSTCIGAQDPYCGWDVVMKK 512
Query: 552 CIFLSPG-TRAAFEQDVSGASTSGL 575
C L + +EQ +S T L
Sbjct: 513 CTSLEESLSMTQWEQSISACPTRNL 537
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 289 bits (739), Expect = 9e-78
Identities = 182/487 (37%), Positives = 264/487 (54%), Gaps = 34/487 (6%)
Query: 61 GADDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKG 120
GA D + + L +G R+ L+R+ L + + W S+ C+ KG
Sbjct: 122 GARDFSQLALDPSGNQLIVGARNYLFRLSL-----ANVSLLQATEWASSEDTRRSCQSKG 176
Query: 121 KQEGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKH 180
K E EC+N+V+VL++ +F+CG+NAF+P+C + + L + I+G+ARCPYDP+H
Sbjct: 177 KTEEECQNYVRVLIVAGRK-VFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRH 235
Query: 181 ANVALFSD-GMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEWGS 239
+ A+ S G L+ ATV DF D IYRSLG P LRT +++SKW EP FV A + G
Sbjct: 236 NSTAVISSQGELYAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFVAAYDIGL 295
Query: 240 HVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSH 299
YFF RE A+E + + V SRVARVCKNDVGG +LE WT+F+KARLNCS PG+
Sbjct: 296 FAYFFLRENAVEHD-CGRTVYSRVARVCKNDVGGR-FLLEDTWTTFMKARLNCSRPGEVP 353
Query: 300 FYFNVLQAVTGVVSLGGRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPE 359
FY+N LQ+ L + ++ VF+T NSI SAVCAF+L+ ++ F G FR Q++P
Sbjct: 354 FYYNELQS---AFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSAISQAFNGPFRYQENPR 410
Query: 360 SIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWIL 419
+ W P+ P P C P + + L + L + LM EAV + P +
Sbjct: 411 AAWLPIAN---PIPNFQCGTLP--ETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVT 465
Query: 420 RTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFE 479
+ +R + + VD+ V+++G+E+GT+LK L ST+ S +LEE
Sbjct: 466 QDSVR--FSHLVVDLVQAKDTLYHVLYIGTESGTILKAL-----STASRSLHGCYLEELH 518
Query: 480 TYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGS 539
P R + L SL + ++ L V+RVP+ RC Y C+G+
Sbjct: 519 VLPPGR---------REPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRS-QGACLGA 568
Query: 540 QDPYCGW 546
+DPYCGW
Sbjct: 569 RDPYCGW 575
>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
Length = 749
Score = 266 bits (679), Expect = 8e-71
Identities = 180/526 (34%), Positives = 263/526 (50%), Gaps = 46/526 (8%)
Query: 77 LFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEG-ECRNFVKVLLL 135
LF+G +++ + L+ + + +KL W + C GK G EC NFVK+L
Sbjct: 67 LFVGAENHVASLNLDNIS----KRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHA 122
Query: 136 RDESTLFVCGSNAFNPVCANYSID--TLQPV-----GDNISGMARCPYDPKHANVALFSD 188
+ + L CG+ AF+P CA + +PV G G + PYDP+H ++
Sbjct: 123 YNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVG 182
Query: 189 GMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEW--------GSH 240
L++ D + D I+RSLG RP+LRT HDS+W EP FV V W
Sbjct: 183 EELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFV-KVFWIPESENPDDDK 241
Query: 241 VYFFFREIAME-FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPG-DS 298
+YFFFRE A+E L ++ VSRV ++C+NDVGG R L +WT+FLKARL CSVPG +
Sbjct: 242 IYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQ-RSLVNKWTTFLKARLVCSVPGVEG 300
Query: 299 HFYFNVLQAVTGVVSLGGR-PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKS 357
+F+ LQ V + S R P++ AVFST S+ GSAVC + + V F G F ++
Sbjct: 301 DTHFDQLQDVFLLSSRDHRTPLLYAVFSTSSSIFQGSAVCVYSMNDVRRAFLGPFAHKEG 360
Query: 358 PESIWTPVPEDQVPRPRPGCCAAPGM-QYNASSALPDDILNFVKTHPLMDEAVPSLGHAP 416
P W + +VP PRPG C + ++++ PDD++ F + HPLM +V G P
Sbjct: 361 PMHQWVSY-QGRVPYPRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRP 419
Query: 417 WILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLE 476
L+ + T++A D A G+ V+F+G++ GTVLK + P S GL LE
Sbjct: 420 LFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSAEGL--LLE 477
Query: 477 EFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNC 536
E + E + S+++ + L A V ++ + RC + C
Sbjct: 478 ELHVF-----------EDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTEC 526
Query: 537 IGSQDPYCGWAPDG-SCIFLSPGTRAAF-EQDVSGASTSGLGDCTG 580
++DPYC W DG +C P + F QDV S L C+G
Sbjct: 527 CLARDPYCAW--DGVACTRFQPSAKRRFRRQDVRNGDPSTL--CSG 568
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 263 bits (671), Expect = 7e-70
Identities = 213/614 (34%), Positives = 298/614 (48%), Gaps = 78/614 (12%)
Query: 6 ASPPRPALLLLLLLLGGAHGLFPEEPPPL-SVAPRDYLNHYPVFVGSGPGRLTPAEGADD 64
A PPRP LLLLLLLL L + PPP +++PR L P+ P AE +
Sbjct: 18 ALPPRPPLLLLLLLL-----LLLQPPPPTWALSPRISL---PLGSEERPFLRFEAEHISN 69
Query: 65 LNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQ-E 123
+ R RTL++G R+ L+ + YQ +L W ++ C KGK +
Sbjct: 70 YTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQ-ELLWGADAEKKQQCSFKGKDPQ 128
Query: 124 GECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGD---NI---SGMARCPYD 177
+C+N++K+LL S LF CG+ AF+P+C +++ D N+ G RCP+D
Sbjct: 129 RDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFD 188
Query: 178 PKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAV-- 235
P + AL DG L+T TV+ F D I RS RPT + W ++P FV +
Sbjct: 189 PNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPT--KTESSLNWLQDPAFVASAYI 246
Query: 236 --EWGS------HVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLK 287
GS +YFFF E EF + E +VSR+AR+CK D GG RVL+++WTSFLK
Sbjct: 247 PESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGE-RVLQQRWTSFLK 305
Query: 288 ARLNCSVPGDSHFYFNVLQAVTGVVSLGGRP------VVLAVFSTP--SNSIPGSAVCAF 339
A+L CS P D F FNVLQ V +L P + VF++ + GSAVC F
Sbjct: 306 AQLLCSRPDDG-FPFNVLQ---DVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVF 361
Query: 340 DLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCC---AAPGMQYNASSALPDDIL 396
+ V VF G ++E W V VP PRPG C +A + N+S LPD +L
Sbjct: 362 TMKDVQRVFSGLYKEVNRETQQWYTVTH-PVPTPRPGACITNSARERKINSSLQLPDRVL 420
Query: 397 NFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLK 456
NF+K H LMD V S +L+ R+Q RVAV G V+FLG+ G + K
Sbjct: 421 NFLKDHFLMDGQVRS---RMLLLQPQARYQ--RVAVHRVPGLHHTYDVLFLGTGDGRLHK 475
Query: 457 FL-VRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFP 515
+ V P +EE + + +GQ + +L LD G L AA
Sbjct: 476 AVSVGPRVH---------IIEELQIF-----------SSGQPVQNLLLDTHRGLLYAASH 515
Query: 516 RCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDGSC----IFLSPGTRAAFEQDVSGAS 571
VV+VP+A C Y C +C+ ++DPYC W+ SC ++ + QD+ GAS
Sbjct: 516 SGVVQVPMANCSLYRSC-GDCLLARDPYCAWS-GSSCKHVSLYQPQLATRPWIQDIEGAS 573
Query: 572 TSGLGDCTGLLRAS 585
L + ++ S
Sbjct: 574 AKDLCSASSVVSPS 587
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 263 bits (671), Expect = 7e-70
Identities = 213/614 (34%), Positives = 298/614 (48%), Gaps = 78/614 (12%)
Query: 6 ASPPRPALLLLLLLLGGAHGLFPEEPPPL-SVAPRDYLNHYPVFVGSGPGRLTPAEGADD 64
A PPRP LLLLLLLL L + PPP +++PR L P+ P AE +
Sbjct: 18 ALPPRPPLLLLLLLL-----LLLQPPPPTWALSPRISL---PLGSEERPFLRFEAEHISN 69
Query: 65 LNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQ-E 123
+ R RTL++G R+ L+ + YQ +L W ++ C KGK +
Sbjct: 70 YTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQ-ELLWGADAEKKQQCSFKGKDPQ 128
Query: 124 GECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGD---NI---SGMARCPYD 177
+C+N++K+LL S LF CG+ AF+P+C +++ D N+ G RCP+D
Sbjct: 129 RDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFD 188
Query: 178 PKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAV-- 235
P + AL DG L+T TV+ F D I RS RPT + W ++P FV +
Sbjct: 189 PNFKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPT--KTESSLNWLQDPAFVASAYI 246
Query: 236 --EWGS------HVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLK 287
GS +YFFF E EF + E +VSR+AR+CK D GG RVL+++WTSFLK
Sbjct: 247 PESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGE-RVLQQRWTSFLK 305
Query: 288 ARLNCSVPGDSHFYFNVLQAVTGVVSLGGRP------VVLAVFSTP--SNSIPGSAVCAF 339
A+L CS P D F FNVLQ V +L P + VF++ + GSAVC F
Sbjct: 306 AQLLCSRPDDG-FPFNVLQ---DVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVF 361
Query: 340 DLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCC---AAPGMQYNASSALPDDIL 396
+ V VF G ++E W V VP PRPG C +A + N+S LPD +L
Sbjct: 362 TMKDVQRVFSGLYKEVNRETQQWYTVTH-PVPTPRPGACITNSARERKINSSLQLPDRVL 420
Query: 397 NFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLK 456
NF+K H LMD V S +L+ R+Q RVAV G V+FLG+ G + K
Sbjct: 421 NFLKDHFLMDGQVRS---RMLLLQPQARYQ--RVAVHRVPGLHHTYDVLFLGTGDGRLHK 475
Query: 457 FL-VRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFP 515
+ V P +EE + + +GQ + +L LD G L AA
Sbjct: 476 AVSVGPRVH---------IIEELQIF-----------SSGQPVQNLLLDTHRGLLYAASH 515
Query: 516 RCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDGSC----IFLSPGTRAAFEQDVSGAS 571
VV+VP+A C Y C +C+ ++DPYC W+ SC ++ + QD+ GAS
Sbjct: 516 SGVVQVPMANCSLYRSC-GDCLLARDPYCAWS-GSSCKHVSLYQPQLATRPWIQDIEGAS 573
Query: 572 TSGLGDCTGLLRAS 585
L + ++ S
Sbjct: 574 AKDLCSASSVVSPS 587
>gi|5174673 semaphorin 3A precursor [Homo sapiens]
Length = 771
Score = 263 bits (671), Expect = 7e-70
Identities = 163/512 (31%), Positives = 258/512 (50%), Gaps = 43/512 (8%)
Query: 77 LFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQE-GECRNFVKVLLL 135
L++G +D+++ +L ++ +K+ W + + + C+ GK EC NF+KVL
Sbjct: 69 LYVGAKDHIFSFDL-----VNIKDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKA 123
Query: 136 RDESTLFVCGSNAFNPVCANYSIDTLQPVGDNI---------SGMARCPYDPKHANVALF 186
+++ L+ CG+ AF+P+C I DNI +G + PYDPK +L
Sbjct: 124 YNQTHLYACGTGAFHPICTYIEIG--HHPEDNIFKLENSHFENGRGKSPYDPKLLTASLL 181
Query: 187 SDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFV--HAVEWGSH---- 240
DG L++ T DF+ D I+R+LG +RT +HDS+W +P F+ H + +
Sbjct: 182 IDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPKFISAHLISESDNPEDD 241
Query: 241 -VYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSH 299
VYFFFRE A++ + K +R+ ++CKND GG R L +WT+FLKARL CSVPG +
Sbjct: 242 KVYFFFRENAIDGEHSGKATHARIGQICKNDFGGH-RSLVNKWTTFLKARLICSVPGPNG 300
Query: 300 F--YFNVLQAVTGVVSLGGR-PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQK 356
+F+ LQ V + + PVV VF+T SN GSAVC + ++ V VF G + +
Sbjct: 301 IDTHFDELQDVFLMNFKDPKNPVVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGPYAHRD 360
Query: 357 SPESIWTPVPEDQVPRPRPGCCAAPGM-QYNASSALPDDILNFVKTHPLMDEAVPSLGHA 415
P W P + +VP PRPG C + ++++ LPDD++ F ++HP M V + +
Sbjct: 361 GPNYQWVPY-QGRVPYPRPGTCPSKTFGGFDSTKDLPDDVITFARSHPAMYNPVFPMNNR 419
Query: 416 PWILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFL 475
P +++T + +Q T++ VD G V+F+G++ GTVLK + P + V L
Sbjct: 420 PIVIKTDVNYQFTQIVVDRVDAEDGQYDVMFIGTDVGTVLKVVSIPKETWYDLE--EVLL 477
Query: 476 EEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKN 535
EE +R + ++EL L V ++P+ RC Y
Sbjct: 478 EEMTVFREPTA-----------ISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAE 526
Query: 536 CIGSQDPYCGWAPDGSCIFLSPGTRAAFEQDV 567
C ++DPYC W + R QD+
Sbjct: 527 CCLARDPYCAWDGSACSRYFPTAKRRTRRQDI 558
>gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]
Length = 748
Score = 261 bits (668), Expect = 2e-69
Identities = 180/526 (34%), Positives = 263/526 (50%), Gaps = 47/526 (8%)
Query: 77 LFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEG-ECRNFVKVLLL 135
LF+G +++ + L+ + + +KL W + C GK G EC NFVK+L
Sbjct: 67 LFVGAENHVASLNLDNIS----KRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHA 122
Query: 136 RDESTLFVCGSNAFNPVCANYSID--TLQPV-----GDNISGMARCPYDPKHANVALFSD 188
+ + L CG+ AF+P CA + +PV G G + PYDP+H ++
Sbjct: 123 YNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVG 182
Query: 189 GMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAVEW--------GSH 240
L++ D + D I+RSLG RP+LRT HDS+W EP FV V W
Sbjct: 183 EELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFV-KVFWIPESENPDDDK 241
Query: 241 VYFFFREIAME-FNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPG-DS 298
+YFFFRE A+E L ++ VSRV ++C+NDVGG R L +WT+FLKARL CSVPG +
Sbjct: 242 IYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQ-RSLVNKWTTFLKARLVCSVPGVEG 300
Query: 299 HFYFNVLQAVTGVVSLGGR-PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKS 357
+F+ LQ V + S R P++ AVFST S+ GSAVC + + V F G F ++
Sbjct: 301 DTHFDQLQDVFLLSSRDHRTPLLYAVFST-SSIFQGSAVCVYSMNDVRRAFLGPFAHKEG 359
Query: 358 PESIWTPVPEDQVPRPRPGCCAAPGM-QYNASSALPDDILNFVKTHPLMDEAVPSLGHAP 416
P W + +VP PRPG C + ++++ PDD++ F + HPLM +V G P
Sbjct: 360 PMHQWVSY-QGRVPYPRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRP 418
Query: 417 WILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLE 476
L+ + T++A D A G+ V+F+G++ GTVLK + P S GL LE
Sbjct: 419 LFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSAEGL--LLE 476
Query: 477 EFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNC 536
E + E + S+++ + L A V ++ + RC + C
Sbjct: 477 ELHVF-----------EDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTEC 525
Query: 537 IGSQDPYCGWAPDG-SCIFLSPGTRAAF-EQDVSGASTSGLGDCTG 580
++DPYC W DG +C P + F QDV S L C+G
Sbjct: 526 CLARDPYCAW--DGVACTRFQPSAKRRFRRQDVRNGDPSTL--CSG 567
>gi|6912650 semaphorin 3E [Homo sapiens]
Length = 775
Score = 256 bits (653), Expect = 9e-68
Identities = 165/517 (31%), Positives = 256/517 (49%), Gaps = 38/517 (7%)
Query: 64 DLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQE 123
DL+ + LF+G RD +Y + LE + +++ W S + C MKGK
Sbjct: 57 DLHTMLLDEYQERLFVGGRDLVYSLSLERISDG----YKEIHWPSTALKMEECIMKGKDA 112
Query: 124 GECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSI-----DTLQPVGDNIS--GMARCPY 176
GEC N+V+VL + + L CG+ AF+PVCA + D L + S G RCP+
Sbjct: 113 GECANYVRVLHHYNRTHLLTCGTGAFDPVCAFIRVGYHLEDPLFHLESPRSERGRGRCPF 172
Query: 177 DPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAV- 235
DP + ++ LF +D+ + DA I+RS+G +RT D + KEP FV +
Sbjct: 173 DPSSSFISTLIGSELFAGLYSDYWSRDAAIFRSMGRLAHIRTEHDDERLLKEPKFVGSYM 232
Query: 236 ------EWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKAR 289
+ VYFFF E A+E + +RV R+C NDVGG R+L +W++FLKAR
Sbjct: 233 IPDNEDRDDNKVYFFFTEKALEAENNAHAIYTRVGRLCVNDVGGQ-RILVNKWSTFLKAR 291
Query: 290 LNCSVPGDSHF--YFNVLQAVTGVVSLGGR-PVVLAVFSTPSNSIPGSAVCAFDLTQVAA 346
L CSVPG + YF+ L+ V + + + PV+ +F+T SN G A+C + ++ + A
Sbjct: 292 LVCSVPGMNGIDTYFDELEDVFLLPTRDHKNPVIFGLFNTTSNIFRGHAICVYHMSSIRA 351
Query: 347 VFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAP--GMQYNASSALPDDILNFVKTHPL 404
F G + ++ PE W+ V E +VP PRPG CA+ G +Y + PDD + F ++HPL
Sbjct: 352 AFNGPYAHKEGPEYHWS-VYEGKVPYPRPGSCASKVNGGRYGTTKDYPDDAIRFARSHPL 410
Query: 405 MDEAVPSLGHAPWILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNAS 464
M +A+ P +++T ++ L ++AVD G V+F+G++ G VLK + N
Sbjct: 411 MYQAIKPAHKKPILVKTDGKYNLKQIAVDRVEAEDGQYDVLFIGTDNGIVLKVITIYNQE 470
Query: 465 TSGTSGLSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVA 524
V LEE + ++ ++S+E+ + L V +V
Sbjct: 471 MESME--EVILEELQIFKDP-----------VPIISMEISSKRQQLYIGSASAVAQVRFH 517
Query: 525 RCQQYSGCMKNCIGSQDPYCGWAPDGSCIFLSPGTRA 561
C Y +C ++DPYC W + GT A
Sbjct: 518 HCDMYGSACADCCLARDPYCAWDGISCSRYYPTGTHA 554
>gi|9910362 semaphorin sem2 [Homo sapiens]
Length = 782
Score = 246 bits (628), Expect = 7e-65
Identities = 195/613 (31%), Positives = 285/613 (46%), Gaps = 66/613 (10%)
Query: 17 LLLLGGAHGLFP-EEPPPLSVAPRDYL--NHYPVFVGSGPGRLTPAEGADDLNIQRVLRV 73
LLL GG+ G P P L ++ RD L N +F+G +G+ +L +
Sbjct: 15 LLLHGGSSGPSPGPSVPRLRLSYRDLLSANRSAIFLGP--------QGSLNLQAMYLDEY 66
Query: 74 NRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQE-GECRNFVKV 132
LF+G D LY + L+ R++ W P C KG+ EC NFV+V
Sbjct: 67 RDRLFLGGLDALYSLRLDQAWPDP----REVLWPPQPGQREECVRKGRDPLTECANFVRV 122
Query: 133 LLLRDESTLFVCGSNAFNPVCANYSIDT-------LQPVGDNISGMARCPYDPKHANVAL 185
L + + L CG+ AF P CA ++ L+P G SG RCP++P +
Sbjct: 123 LQPHNRTHLLACGTGAFQPTCALITVGHRGEHVLHLEP-GSVESGRGRCPHEPSRPFAST 181
Query: 186 FSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAV-------EWG 238
F DG L+T DFL +A+I+RS G RP LR+ D +P FV A +
Sbjct: 182 FIDGELYTGLTADFLGREAMIFRSGGPRPALRS-DSDQSLLHDPRFVMAARIPENSDQDN 240
Query: 239 SHVYFFFRE-IAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGD 297
VYFFF E + V VSRV RVC ND GG RVL +W++FLKARL CSVPG
Sbjct: 241 DKVYFFFSETVPSPDGGSNHVTVSRVGRVCVNDAGGQ-RVLVNKWSTFLKARLVCSVPGP 299
Query: 298 --SHFYFNVLQAVTGVVSLGGRPV-VLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFRE 354
+ +F+ L+ V + G+ + V A+FST S G AVC + + + VF G F
Sbjct: 300 GGAETHFDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCVYHMADIWEVFNGPFAH 359
Query: 355 QKSPESIWTPVPEDQVPRPRPGCC-----AAPGMQYNASSALPDDILNFVKTHPLMDEAV 409
+ P+ W P +VP PRPG C A PG + ++ PD++L F + HPLM V
Sbjct: 360 RDGPQHQWGPYG-GKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFARAHPLMFWPV 418
Query: 410 PSLGHAPWILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTS 469
P +++T + QL ++ VD G V+FLG+++G+VLK + ++
Sbjct: 419 RPRHGRPVLVKTHLAQQLHQIVVDRVEAEDGTYDVIFLGTDSGSVLKVIALQAGGSAEPE 478
Query: 470 GLSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQY 529
V LEE + ++ + +E+ L V ++ + +C+ Y
Sbjct: 479 --EVVLEELQVFK-----------VPTPITEMEISVKRQMLYVGSRLGVAQLRLHQCETY 525
Query: 530 SGCMKNCIGSQDPYCGWAPDG-SCIFLSP--GTRAAFEQDVSGASTSGLGDCTGLLRASL 586
C ++DPYC W DG SC P G R QD+ + + C G S
Sbjct: 526 GTACAECCLARDPYCAW--DGASCTHYRPSLGKRRFRRQDIRHGNPA--LQCLG---QSQ 578
Query: 587 SEDRAGLVSVNLL 599
E+ GLV+ ++
Sbjct: 579 EEEAVGLVAATMV 591
>gi|41406086 semaphorin 3D [Homo sapiens]
Length = 777
Score = 246 bits (627), Expect = 9e-65
Identities = 177/588 (30%), Positives = 287/588 (48%), Gaps = 63/588 (10%)
Query: 11 PALLLL--LLLLGGAHGLFPEEPPPLSVAPRDYL--NHYPVFVGSGPGRLTPAEGADDLN 66
PAL++L +L G + P L + +D L N F+GS G L+
Sbjct: 20 PALMMLSMTMLFLPVTGTLKQNIPRLKLTYKDLLLSNSCIPFLGSSEG----------LD 69
Query: 67 IQRVL--RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEG 124
Q +L L +G +D+++ + L +K+ W + + +C++ GK
Sbjct: 70 FQTLLLDEERGRLLLGAKDHIFLLSLVDLNKNF----KKIYWPAAKERVELCKLAGKDAN 125
Query: 125 -ECRNFVKVLLLRDESTLFVCGSNAFNPVCAN-----YSIDTLQPVGDNI--SGMARCPY 176
EC NF++VL +++ ++VCG+ AF+P+C Y D + + + SG +CP+
Sbjct: 126 TECANFIRVLQPYNKTHIYVCGTGAFHPICGYIDLGVYKEDIIFKLDTHNLESGRLKCPF 185
Query: 177 DPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLG---DRPTLRTVKHDSKWFKEPYFVH 233
DP+ ++ +D L++ T +DFL D RSLG D +RT + W F+
Sbjct: 186 DPQQPFASVMTDEYLYSGTASDFLGKDTAFTRSLGPTHDHHYIRTDISEHYWLNGAKFIG 245
Query: 234 AV-------EWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFL 286
+YFFFRE + E + +K ++SRV RVCKNDVGG R L +WT+FL
Sbjct: 246 TFFIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGGQ-RSLINKWTTFL 304
Query: 287 KARLNCSVPGD--SHFYFNVLQAVTGVVSLGGR-PVVLAVFSTPSNSIPGSAVCAFDLTQ 343
KARL CS+PG + YF+ LQ + + + R PVV VF+T S+ GSAVC + +
Sbjct: 305 KARLICSIPGSDGADTYFDELQDIYLLPTRDERNPVVYGVFTTTSSIFKGSAVCVYSMAD 364
Query: 344 VAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYN----ASSALPDDILNFV 399
+ AVF G + ++S + W + ++P PRPG C P Y+ ++ PDD+++F+
Sbjct: 365 IRAVFNGPYAHKESADHRWVQY-DGRIPYPRPGTC--PSKTYDPLIKSTRDFPDDVISFI 421
Query: 400 KTHPLMDEAVPSLGHAPWILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLV 459
K H +M ++V + P R + ++LT++ VD G V+FLG++ GTVLK +
Sbjct: 422 KRHSVMYKSVYPVAGGPTFKRINVDYRLTQIVVDHVIAEDGQYDVMFLGTDIGTVLKVV- 480
Query: 460 RPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVV 519
+ S + V LEE + ++ +L++EL L +V
Sbjct: 481 --SISKEKWNMEEVVLEELQIFKHSSI-----------ILNMELSLKQQQLYIGSRDGLV 527
Query: 520 RVPVARCQQYSGCMKNCIGSQDPYCGWAPDGSCIFLSPGTRAAFEQDV 567
++ + RC Y +C ++DPYC W + + R A QDV
Sbjct: 528 QLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPTSKRRARRQDV 575
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 241 bits (614), Expect = 3e-63
Identities = 168/555 (30%), Positives = 283/555 (50%), Gaps = 48/555 (8%)
Query: 60 EGADDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMK 119
+G D + + TL++G R+ + ++++ P L+ + W ++ + C K
Sbjct: 59 KGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLK--NMIPWPASDRKKSECAFK 116
Query: 120 GKQ-EGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDT--LQPVGDN--ISGMARC 174
K E +C NF++VL+ + + L+ CG+ AF+P C + L P+ ++ + G +
Sbjct: 117 KKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQS 176
Query: 175 PYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHA 234
P+DP H + A+ DGML++ T+ +FL + ++ R+LG +P L+T + FV A
Sbjct: 177 PFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA 236
Query: 235 VEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSV 294
+ VYFFF E A EF++ E++ SRVARVCKNDVGG ++L+K+WT+FLKA+L C+
Sbjct: 237 IPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGE-KLLQKKWTTFLKAQLLCTQ 295
Query: 295 PGDSHFYFNVLQ-AVTGVVSLGGRPVVLAVFST--PSNSIPGSAVCAFDLTQVAAVFEGR 351
PG FNV++ AV P + AVF++ SAVCAF L + VF+G+
Sbjct: 296 PG--QLPFNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGK 353
Query: 352 FREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPS 411
++E S WT + PRPG C+ D L F+K H LMDE V
Sbjct: 354 YKELNKETSRWTTYRGPET-NPRPGSCSV--------GPSSDKALTFMKDHFLMDEQVVG 404
Query: 412 LGHAPWILRTLMRHQLTRVAVDVGAGPWG-NQTVVFLGSEAGTVLKFLVRPNASTSGTSG 470
P ++++ + + TR+AV+ G G + V++LG+ G++ K +V ++S
Sbjct: 405 ---TPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAH---- 455
Query: 471 LSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYS 530
+EE + + PD + + +L+L G + F V RVP A C Y
Sbjct: 456 ---LVEEIQLF-PD----------PEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYE 501
Query: 531 GCMKNCIGSQDPYCGWAPDG-SCIFLSPGTRAAFEQDVSGASTSGLGDCTGLLRASLSED 589
C+ +C+ ++DP+C W P+ +C LS +++QD+ + + R+ +
Sbjct: 502 SCV-DCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQS 560
Query: 590 RAGLVSVNLLVTSSV 604
R ++ L V +S+
Sbjct: 561 RPQIIKEVLAVPNSI 575
>gi|5454048 semaphorin 3C [Homo sapiens]
Length = 751
Score = 240 bits (613), Expect = 4e-63
Identities = 179/598 (29%), Positives = 284/598 (47%), Gaps = 53/598 (8%)
Query: 77 LFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQEGE-CRNFVKVLLL 135
+++G +D++ + + + L + W ++ + C+M GK C NFV+V+
Sbjct: 66 IYVGSKDHILSLNINNISQEAL----SVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQT 121
Query: 136 RDESTLFVCGSNAFNPVCA-----NYSIDTLQPVGDNI-SGMARCPYDPKHANVALFSDG 189
+ + L+VCGS AF+PVC S D + + SG RC ++P V++ +
Sbjct: 122 FNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINE 181
Query: 190 MLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFV--HAVEWG-----SHVY 242
LF+ DF+ DA I+RSL R +RT +H+SKW EP FV H + G + VY
Sbjct: 182 ELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVY 241
Query: 243 FFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDS--HF 300
FFF+E + N K + S +AR+C ND GG R L +WT+FLKARL CSV +
Sbjct: 242 FFFKEKLTDNNRSTKQIHSMIARICPNDTGGL-RSLVNKWTTFLKARLVCSVTDEDGPET 300
Query: 301 YFNVLQAVTGVVSLGGR-PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPE 359
+F+ L+ V + + R +V +F+T S+ GSAVC + L+ + VF G F ++ P
Sbjct: 301 HFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPN 360
Query: 360 SIWTPVPEDQVPRPRPGCCAAPGMQYN--ASSALPDDILNFVKTHPLMDEAVPSLGHAPW 417
+ ++P PRPG C N + PDD++ F++ HPLM ++ + P
Sbjct: 361 HQLISY-QGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPL 419
Query: 418 ILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLVRP-NASTSGTSGLSVFLE 476
I+R ++ T++AVD G V+FLG++ GTV K +V P N S SG + LE
Sbjct: 420 IVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSG----ELILE 475
Query: 477 EFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNC 536
E E ++ + ++++ + L + V +V + RC Y +C
Sbjct: 476 ELEVFK-----------NHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADC 524
Query: 537 IGSQDPYCGWAPDGSCIFLSPGTRAAFEQDVSGASTSGLGDCTGLLRASLSEDRAGLVSV 596
++DPYC W F G R + QDV + L C G +L R V
Sbjct: 525 CLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNP--LTQCRGF---NLKAYRNAAEIV 579
Query: 597 NLLVTSSVAAFVVGAVVSGFSVGWFVGLRERRELARRKD---KEAILAHGAGEAVLSV 651
V ++ S+ W + +++ RRK+ E I+A G + SV
Sbjct: 580 QYGVKNNTTFLECAPKSPQASIKWLL----QKDKDRRKEVKLNERIIATSQGLLIRSV 633
>gi|188497703 semaphorin 3F [Homo sapiens]
Length = 785
Score = 237 bits (604), Expect = 4e-62
Identities = 165/544 (30%), Positives = 260/544 (47%), Gaps = 76/544 (13%)
Query: 77 LFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQ-EGECRNFVKVLLL 135
+++G +D + ++L L + W ++P I C + GK GEC NFV+++
Sbjct: 69 MYVGSKDYVLSLDLHDINREPLI----IHWAASPQRIEECVLSGKDVNGECGNFVRLIQP 124
Query: 136 RDESTLFVCGSNAFNPVC------------------------ANYSIDTLQPVG-----D 166
+ + L+VCG+ A+NP+C + + L+P+ D
Sbjct: 125 WNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTAPRQD 184
Query: 167 NI---------SGMARCPYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLR 217
I SG +CPYDPK + + L+ DF+ DA I+R+LG + +R
Sbjct: 185 YIFYLEPERLESGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTAMR 244
Query: 218 TVKHDSKWFKEPYFVH-------AVEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKND 270
T +++S+W +P F+H A +YFFFRE + E V +R+ R+C ND
Sbjct: 245 TDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQ-SPAVYARIGRICLND 303
Query: 271 VGGSPRVLEKQWTSFLKARLNCSVPGDS--HFYFNVLQAVTGVVSLGGR-PVVLAVFSTP 327
GG ++ K W++FLKARL CSVPG+ +F+ LQ V + R PV+ AVF++
Sbjct: 304 DGGHCCLVNK-WSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVRNPVIYAVFTSS 362
Query: 328 SNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNA 387
+ GSAVC + + + VF G F ++ P W P ++P PRPG C PG +
Sbjct: 363 GSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPF-SGKMPYPRPGTC--PGGTFTP 419
Query: 388 S----SALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTRVAVDVGAGPWGNQT 443
S PD+++NF+++HPLM +AV L P ++RT ++LT +AVD G
Sbjct: 420 SMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTIAVDQVDAADGRYE 479
Query: 444 VVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGETGQRLLSLEL 503
V+FLG++ GTV K +V P + LEE E ++ P +T + +
Sbjct: 480 VLFLGTDRGTVQKVIVLPKDDQELE---ELMLEEVEVFKD-----PAPVKT------MTI 525
Query: 504 DAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDGSCIFLSPGTRAAF 563
+ L A V + + RCQ Y +C ++DPYC W + + R +
Sbjct: 526 SSKRQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSKRRSR 585
Query: 564 EQDV 567
QDV
Sbjct: 586 RQDV 589
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 236 bits (603), Expect = 5e-62
Identities = 173/523 (33%), Positives = 264/523 (50%), Gaps = 52/523 (9%)
Query: 77 LFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGKQ-EGECRNFVKVLLL 135
L++G R+ L+ +E L Q ++W + C KGK + EC NF++ L
Sbjct: 65 LYVGAREALFAFSMEA-----LELQGAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQP 119
Query: 136 RDESTLFVCGSNAFNPVCANYSIDTLQ-PVGDNISGMARCPYDPKHANVALFSDGMLFTA 194
+ S L+VCG+ AF P C ++ T G+ G +CPYDP + L DG L++A
Sbjct: 120 YNASHLYVCGTYAFQPKCTYVNMLTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSA 179
Query: 195 TVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAV----EWGS------HVYFF 244
T+ +FL + +I R++G +++T ++ + W EP+FV + GS VYFF
Sbjct: 180 TLNNFLGTEPIILRNMGPHHSMKT-EYLAFWLNEPHFVGSAYVPESVGSFTGDDDKVYFF 238
Query: 245 FREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNV 304
FRE A+E + + VV+RVARVCK D+GG+ R L+++WT+FLKARL CS P + YFN
Sbjct: 239 FRERAVESDCYAEQVVARVARVCKGDMGGA-RTLQRKWTTFLKARLACSAP-NWQLYFNQ 296
Query: 305 LQAVTGVVSLG-GRPVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWT 363
LQA+ + VF + SA+C + L ++ VFEG ++E W
Sbjct: 297 LQAMHTLQDTSWHNTTFFGVFQAQWGDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWD 356
Query: 364 PVPEDQVPRPRPGCCAAPGMQ---YNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILR 420
D VP PRPG C + Y +S LPD+ILNFVK HPLM+E V P +++
Sbjct: 357 RY-TDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVK 415
Query: 421 TLMRHQLTRVAVDVGAGPWG-NQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFL-EEF 478
T + D G G TV+F+G+ G +LK + + G V L EE
Sbjct: 416 --KGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKAV---------SLGPWVHLIEEL 464
Query: 479 ETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIG 538
+ + + + SL L + L A +V++PVA C +Y C +C+
Sbjct: 465 QLF------------DQEPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKYRSC-ADCVL 511
Query: 539 SQDPYCGWAPDGS-CIFLSPGTRAAFEQDVSGASTSGLGDCTG 580
++DPYC W+ + S C+ + + + Q V + TSG+ + G
Sbjct: 512 ARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGICNLRG 554
>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
Length = 738
Score = 234 bits (598), Expect = 2e-61
Identities = 166/500 (33%), Positives = 266/500 (53%), Gaps = 48/500 (9%)
Query: 76 TLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGK-QEGECRNFVKVLL 134
TL+IG R+ ++ V + Q ++ W+ + C KGK ++ EC N+++VL
Sbjct: 61 TLYIGAREAVFAVNALNISEK----QHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQ 116
Query: 135 LRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGMLFTA 194
++L+VCG+NAF P C + ++ + + +G N G RCP+DP H+ ++ DG L++
Sbjct: 117 PLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSG 176
Query: 195 TVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHA----------VEWGSHVYFF 244
T +FL + +I R+ P LRT ++ W EP FV A VYFF
Sbjct: 177 TSYNFLGSEPIISRNSSHSP-LRT-EYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFF 234
Query: 245 FREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNV 304
F E+++E+ ++ +V++ R+ARVCK D GG R L+K+WTSFLKARL CS P DS FNV
Sbjct: 235 FTEVSVEYEFVFRVLIPRIARVCKGDQGGL-RTLQKKWTSFLKARLICSRP-DSGLVFNV 292
Query: 305 LQAVTGVVSLGGR-PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVF-EGRFREQKSPESIW 362
L+ V + S G + PV A+F+ N++ SAVCA++L+ VF G++ + + E
Sbjct: 293 LRDVFVLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSH 352
Query: 363 TPVP--EDQVPRPRPGCC---AAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPW 417
T VP+PRPG C A Y +S LPD L FVK HPLMD++V + + P
Sbjct: 353 TKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPR 412
Query: 418 ILRTLMRHQLTRVAVDVGAGPWGN-QTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLE 476
+++ + + T++ VD G V+F+ ++ G + K + +A +E
Sbjct: 413 LIKKDVNY--TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVH--------IIE 462
Query: 477 EFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNC 536
E + ++ E Q LL L + + A VV+ P+A C ++ C ++C
Sbjct: 463 ETQLFQ--------DFEPVQTLL-LSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTC-EDC 512
Query: 537 IGSQDPYCGWA-PDGSCIFL 555
+ ++DPYC W+ P +C+ L
Sbjct: 513 VLARDPYCAWSPPTATCVAL 532
>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
Length = 862
Score = 234 bits (598), Expect = 2e-61
Identities = 166/500 (33%), Positives = 266/500 (53%), Gaps = 48/500 (9%)
Query: 76 TLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMKGK-QEGECRNFVKVLL 134
TL+IG R+ ++ V + Q ++ W+ + C KGK ++ EC N+++VL
Sbjct: 61 TLYIGAREAVFAVNALNISEK----QHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQ 116
Query: 135 LRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVALFSDGMLFTA 194
++L+VCG+NAF P C + ++ + + +G N G RCP+DP H+ ++ DG L++
Sbjct: 117 PLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSG 176
Query: 195 TVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHA----------VEWGSHVYFF 244
T +FL + +I R+ P LRT ++ W EP FV A VYFF
Sbjct: 177 TSYNFLGSEPIISRNSSHSP-LRT-EYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFF 234
Query: 245 FREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNV 304
F E+++E+ ++ +V++ R+ARVCK D GG R L+K+WTSFLKARL CS P DS FNV
Sbjct: 235 FTEVSVEYEFVFRVLIPRIARVCKGDQGGL-RTLQKKWTSFLKARLICSRP-DSGLVFNV 292
Query: 305 LQAVTGVVSLGGR-PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVF-EGRFREQKSPESIW 362
L+ V + S G + PV A+F+ N++ SAVCA++L+ VF G++ + + E
Sbjct: 293 LRDVFVLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSH 352
Query: 363 TPVP--EDQVPRPRPGCC---AAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPW 417
T VP+PRPG C A Y +S LPD L FVK HPLMD++V + + P
Sbjct: 353 TKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPR 412
Query: 418 ILRTLMRHQLTRVAVDVGAGPWGN-QTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLE 476
+++ + + T++ VD G V+F+ ++ G + K + +A +E
Sbjct: 413 LIKKDVNY--TQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVH--------IIE 462
Query: 477 EFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNC 536
E + ++ E Q LL L + + A VV+ P+A C ++ C ++C
Sbjct: 463 ETQLFQ--------DFEPVQTLL-LSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTC-EDC 512
Query: 537 IGSQDPYCGWA-PDGSCIFL 555
+ ++DPYC W+ P +C+ L
Sbjct: 513 VLARDPYCAWSPPTATCVAL 532
>gi|19923279 semaphorin W [Homo sapiens]
Length = 770
Score = 234 bits (596), Expect = 3e-61
Identities = 191/596 (32%), Positives = 272/596 (45%), Gaps = 66/596 (11%)
Query: 4 PRASPPRPA-----LLLLLLLLGGAHGLFPEEPPPLSVAPRDYLNHYPVFVGSGPGRLTP 58
PR P +P LLLL +L G G P P S+ + LT
Sbjct: 8 PRPGPGQPTASPFPLLLLAVLSGPVSGRVPRSVPRTSLP-----------ISEADSCLTR 56
Query: 59 AEGADDLNIQRVL--RVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVC 116
N +L + TL++G RD ++ + L P S E R++ W + C
Sbjct: 57 FAVPHTYNYSVLLVDPASHTLYVGARDTIFALSL--PFSGER--PRRIDWMVPEAHRQNC 112
Query: 117 RMKGKQEGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPY 176
R KGK+E EC NFV++L + + S L CG+ AF+P C + Q V SG +CP+
Sbjct: 113 RKKGKKEDECHNFVQILAIANASHLLTCGTFAFDPKCGVIDVSRFQQVERLESGRGKCPF 172
Query: 177 DPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHAV- 235
+P + A+ + G+L+ ATV ++L + +I R++G W P FV AV
Sbjct: 173 EPAQRSAAVMAGGVLYAATVKNYLGTEPIITRAVGRAEDWIRTDTLPSWLNAPAFVAAVA 232
Query: 236 ----EWG-----SHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFL 286
EWG +YFFF E + F+ E++ V RVARVC D+GG + L+++WT+FL
Sbjct: 233 LSPAEWGDEDGDDEIYFFFTETSRAFDSYERIKVPRVARVCAGDLGGR-KTLQQRWTTFL 291
Query: 287 KARLNCSVPGDSH-FYFNVLQAVTGV-VSLG-GRPVVLAVFSTPSNSIPGSAVCAFDLTQ 343
KA L C PG H +VLQ V + LG G P+ +FS+ SAVCAF
Sbjct: 292 KADLLC--PGPEHGRASSVLQDVAVLRPELGAGTPIFYGIFSSQWEGATISAVCAFRPQD 349
Query: 344 VAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQ---YNASSALPDDILNFVK 400
+ V G FRE K + PV ++ VP+PRPG C M+ + +S +LPD +L F++
Sbjct: 350 IRTVLNGPFRELKHDCNRGLPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIR 409
Query: 401 THPLMDEAV-PSLGHAPWILRTLMRHQLTRVAVDVGAGPWGNQTVVFLGSEAGTVLKFLV 459
HPLMD V P+ GH +L T L VA V + V++LG+E G L V
Sbjct: 410 DHPLMDRPVFPADGHP--LLVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGH-LHRAV 466
Query: 460 RPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVV 519
R A S L++F E Q + +++L LL V
Sbjct: 467 RIGAQLSVLEDLALFPEP------------------QPVENMKL--YHSWLLVGSRTEVT 506
Query: 520 RVPVARCQQYSGCMKNCIGSQDPYCGWAPDGSCIFLSPGTRAAFEQDVSGASTSGL 575
+V C + C CI +QDP C W+ G QD+ A S L
Sbjct: 507 QVNTTNCGRLQSC-SECILAQDPVCAWSFRLDECVAHAGEHRGLVQDIESADVSSL 561
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 212 bits (539), Expect = 1e-54
Identities = 160/500 (32%), Positives = 234/500 (46%), Gaps = 68/500 (13%)
Query: 102 RKLTWRSNPSDINVCRMKGKQ-EGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDT 160
+++ W ++P + C KGK + EC N V+ L + + L+ CG++AF P+CA +
Sbjct: 90 KEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEA 149
Query: 161 LQPVGDNISGMARCPYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVK 220
G +CPYDP L DG L+TAT +F +I + R +LRT +
Sbjct: 150 FTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDI--RRSRHPHSLRTEE 207
Query: 221 HDSKWFKEPYFVH----------AVEWGSHVYFFFREIAME------FNYLEKVVVSRVA 264
W + FV AV VY+FF E A E V+RVA
Sbjct: 208 TPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVA 267
Query: 265 RVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSL----GGRPVV 320
RVCK D+GG ++L+K+WTSFLKARL C +P + + + GV SL R
Sbjct: 268 RVCKGDLGGK-KILQKKWTSFLKARLICHIP--------LYETLRGVCSLDAETSSRTHF 318
Query: 321 LAVF--STPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCC 378
A F ST ++ SA+C +DL ++ AVF G + E + W E VP PRPG C
Sbjct: 319 YAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRY-EGGVPEPRPGSC 377
Query: 379 AAPGMQ---YNASSALPDDILNFVKTHPLMDE-AVPSLGHAPWILRTLMRHQLTRVAVDV 434
++ YN+S LP +L+FVK HPLM VP+ G + R + LT V
Sbjct: 378 ITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTT 437
Query: 435 GAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGET 494
AGP ++FLG+ G + K +V SG+ + +EE + +R
Sbjct: 438 PAGP--TYDLLFLGTADGWIHKAVVL-------GSGMHI-IEETQVFR-----------E 476
Query: 495 GQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDGSCIF 554
Q + +L + L P V+++P++ C +Y C +CI ++DPYCGW P
Sbjct: 477 SQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCY-DCILARDPYCGWDPGTHACA 535
Query: 555 L-------SPGTRAAFEQDV 567
S G+R A QD+
Sbjct: 536 AATTIANRSQGSRTALIQDI 555
>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
Length = 666
Score = 123 bits (309), Expect = 7e-28
Identities = 130/473 (27%), Positives = 204/473 (43%), Gaps = 74/473 (15%)
Query: 113 INVCRMKGK--QEGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISG 170
+N+ KG + +C N++ +L R E L CG+NA +P C N T+ P+G+ + G
Sbjct: 111 VNIGSTKGSCLDKRDCENYITLLERRSEG-LLACGTNARHPSCWNLVNGTVVPLGE-MRG 168
Query: 171 MARCPYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWF---- 226
A P+ P ++ LF +++ I Y G P R ++ +S+ +
Sbjct: 169 YA--PFSPDENSLVLFEGDEVYST-------IRKQEYN--GKIPRFRRIRGESELYTSDT 217
Query: 227 --KEPYFVHAV------EWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVL 278
+ P F+ A + +Y+FFRE + N + VSRVA++C+ D GG +
Sbjct: 218 VMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLS 277
Query: 279 EKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGR---PVVLAVFSTPSNSIPGSA 335
+W +FLKA L CS ++ FN LQ V + G+ V VFS P N SA
Sbjct: 278 VSKWNTFLKAMLVCS-DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SA 333
Query: 336 VCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDI 395
VC + L + VF R K S +P PRPG C P Q +P +
Sbjct: 334 VCVYSLGDIDKVF--RTSSLKGYHS--------SLPNPRPGKC-LPDQQ-----PIPTET 377
Query: 396 LNFVKTHPLMDEAVPSLGHAPWILRTLMRH---QLTRVAVDVGAGPWGNQ-TVVFLGSEA 451
HP + + V +G L+T + H +VAV G V++L ++
Sbjct: 378 FQVADRHPEVAQRVEPMGP----LKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDR 433
Query: 452 GTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLL 511
GT+ K +V P + + E + +R + ++ LDA L
Sbjct: 434 GTIHK-VVEPGEQ---EHSFAFNIMEIQPFR-----------RAAAIQTMSLDAERRKLY 478
Query: 512 AAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDGSCIFLSPGTRAAFE 564
+ V +VP+ C+ Y G C+ S+DPYCGW G CI + R+ +
Sbjct: 479 VSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGW-DQGRCISIYSSERSVLQ 530
>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
Length = 652
Score = 122 bits (305), Expect = 2e-27
Identities = 127/459 (27%), Positives = 198/459 (43%), Gaps = 72/459 (15%)
Query: 125 ECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVA 184
+C N++ +L R E L CG+NA +P C N T+ P+G+ + G A P+ P ++
Sbjct: 111 DCENYITLLERRSEG-LLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENSLV 166
Query: 185 LFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWF------KEPYFVHAV--- 235
LF +++ I Y G P R ++ +S+ + + P F+ A
Sbjct: 167 LFEGDEVYST-------IRKQEYN--GKIPRFRRIRGESELYTSDTVMQNPQFIKATIVH 217
Query: 236 ---EWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNC 292
+ +Y+FFRE + N + VSRVA++C+ D GG + +W +FLKA L C
Sbjct: 218 QDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVC 277
Query: 293 SVPGDSHFYFNVLQAVTGVVSLGGR---PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFE 349
S ++ FN LQ V + G+ V VFS P N SAVC + L + VF
Sbjct: 278 S-DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF- 332
Query: 350 GRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAV 409
R K S +P PRPG C P Q +P + HP + + V
Sbjct: 333 -RTSSLKGYHS--------SLPNPRPGKC-LPDQQ-----PIPTETFQVADRHPEVAQRV 377
Query: 410 PSLGHAPWILRTLMRH---QLTRVAVDVGAGPWGNQ-TVVFLGSEAGTVLKFLVRPNAST 465
+G L+T + H +VAV G V++L ++ GT+ K +V P
Sbjct: 378 EPMGP----LKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHK-VVEPGEQ- 431
Query: 466 SGTSGLSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVAR 525
+ + E + +R + ++ LDA L + V +VP+
Sbjct: 432 --EHSFAFNIMEIQPFR-----------RAAAIQTMSLDAERRKLYVSSQWEVSQVPLDL 478
Query: 526 CQQYSGCMKNCIGSQDPYCGWAPDGSCIFLSPGTRAAFE 564
C+ Y G C+ S+DPYCGW G CI + R+ +
Sbjct: 479 CEVYGGGCHGCLMSRDPYCGW-DQGRCISIYSSERSVLQ 516
>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
Length = 501
Score = 98.6 bits (244), Expect = 2e-20
Identities = 103/373 (27%), Positives = 158/373 (42%), Gaps = 59/373 (15%)
Query: 211 GDRPTLRTVKHDSKWF------KEPYFVHAV------EWGSHVYFFFREIAMEFNYLEKV 258
G P R ++ +S+ + + P F+ A + +Y+FFRE + N +
Sbjct: 33 GKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPEAPL 92
Query: 259 VVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGR- 317
VSRVA++C+ D GG + +W +FLKA L CS ++ FN LQ V + G+
Sbjct: 93 NVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCS-DAATNKNFNRLQDVFLLPDPSGQW 151
Query: 318 --PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRP 375
V VFS P N SAVC + L + VF R K S +P PRP
Sbjct: 152 RDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLKGYHS--------SLPNPRP 198
Query: 376 GCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRH---QLTRVAV 432
G C P Q +P + HP + + V +G L+T + H +VAV
Sbjct: 199 GKC-LPDQQ-----PIPTETFQVADRHPEVAQRVEPMGP----LKTPLFHSKYHYQKVAV 248
Query: 433 DVGAGPWGNQ-TVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGG 491
G V++L ++ GT+ K +V P + + E + +R
Sbjct: 249 HRMQASHGETFHVLYLTTDRGTIHK-VVEPGEQ---EHSFAFNIMEIQPFR--------- 295
Query: 492 GETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDGS 551
+ ++ LDA L + V +VP+ C+ Y G C+ S+DPYCGW G
Sbjct: 296 --RAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGW-DQGR 352
Query: 552 CIFLSPGTRAAFE 564
CI + R+ +
Sbjct: 353 CISIYSSERSVLQ 365
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,281,521
Number of Sequences: 37866
Number of extensions: 2605295
Number of successful extensions: 19807
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 151
Number of HSP's successfully gapped in prelim test: 961
Number of HSP's that attempted gapping in prelim test: 14778
Number of HSP's gapped (non-prelim): 4493
length of query: 888
length of database: 18,247,518
effective HSP length: 111
effective length of query: 777
effective length of database: 14,044,392
effective search space: 10912492584
effective search space used: 10912492584
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.