BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|197116361 inositol polyphosphate-4-phosphatase, type 1 isoform c [Homo sapiens] (972 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|197116361 inositol polyphosphate-4-phosphatase, type 1 isofor... 1953 0.0 gi|197116359 inositol polyphosphate-4-phosphatase, type 1 isofor... 1947 0.0 gi|4755140 inositol polyphosphate-4-phosphatase, type 1 isoform ... 1833 0.0 gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform ... 1750 0.0 gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105k... 737 0.0 gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105k... 737 0.0 gi|47578115 DEP domain containing 2 isoform a [Homo sapiens] 124 3e-28 gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent R... 120 8e-27 gi|88703066 copine-like protein [Homo sapiens] 36 0.15 gi|25141328 copine 7 isoform a [Homo sapiens] 35 0.26 gi|7656993 copine 7 isoform b [Homo sapiens] 35 0.26 gi|25141323 copine V [Homo sapiens] 35 0.34 gi|226498192 atonal homolog 8 [Homo sapiens] 34 0.76 gi|126090909 engrailed homeobox 1 [Homo sapiens] 34 0.76 gi|25121972 copine VIII [Homo sapiens] 34 0.76 gi|169201827 PREDICTED: similar to hCG1798126 [Homo sapiens] 33 0.99 gi|169201475 PREDICTED: similar to hCG1798126, partial [Homo sap... 33 0.99 gi|169190743 PREDICTED: similar to hCG1798126 [Homo sapiens] 33 0.99 gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens] 33 1.3 gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens] 33 1.3 gi|242247251 WW and C2 domain containing 1 isoform 1 [Homo sapiens] 33 1.3 gi|126116565 MYC binding protein 2 [Homo sapiens] 33 1.3 gi|34304360 nephrocystin 3 [Homo sapiens] 33 1.7 gi|116268109 nucleotide-binding oligomerization domains 27 [Homo... 33 1.7 gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens] 32 2.2 gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Hom... 32 3.8 gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Hom... 32 3.8 gi|38201677 teashirt family zinc finger 1 [Homo sapiens] 32 3.8 gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 31 6.4 gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo... 30 8.4 >gi|197116361 inositol polyphosphate-4-phosphatase, type 1 isoform c [Homo sapiens] Length = 972 Score = 1953 bits (5060), Expect = 0.0 Identities = 972/972 (100%), Positives = 972/972 (100%) Query: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL Sbjct: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60 Query: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY Sbjct: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120 Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180 Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240 Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300 Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360 Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQV 420 GAPAAHCQGFKSGGLRKKLHKFEETKKHTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQV Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQV 420 Query: 421 SYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASK 480 SYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASK Sbjct: 421 SYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASK 480 Query: 481 ASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRV 540 ASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRV Sbjct: 481 ASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRV 540 Query: 541 DKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTA 600 DKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTA Sbjct: 541 DKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTA 600 Query: 601 CHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIA 660 CHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIA Sbjct: 601 CHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIA 660 Query: 661 TYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEE 720 TYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEE Sbjct: 661 TYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEE 720 Query: 721 LAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPRE 780 LAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPRE Sbjct: 721 LAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPRE 780 Query: 781 IQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDC 840 IQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDC Sbjct: 781 IQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDC 840 Query: 841 LPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMS 900 LPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMS Sbjct: 841 LPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMS 900 Query: 901 VTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHY 960 VTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHY Sbjct: 901 VTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHY 960 Query: 961 RPPEGTYGKVET 972 RPPEGTYGKVET Sbjct: 961 RPPEGTYGKVET 972 >gi|197116359 inositol polyphosphate-4-phosphatase, type 1 isoform d [Homo sapiens] Length = 977 Score = 1947 bits (5044), Expect = 0.0 Identities = 972/977 (99%), Positives = 972/977 (99%), Gaps = 5/977 (0%) Query: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL Sbjct: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60 Query: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY Sbjct: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120 Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180 Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240 Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300 Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360 Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKH-----TSSGCQSIIYIPQDVVRAKEIIAQINT 415 GAPAAHCQGFKSGGLRKKLHKFEETKKH TSSGCQSIIYIPQDVVRAKEIIAQINT Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420 Query: 416 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 475 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD Sbjct: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480 Query: 476 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 535 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC Sbjct: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540 Query: 536 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 595 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST Sbjct: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 600 Query: 596 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 655 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS Sbjct: 601 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 660 Query: 656 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 715 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS Sbjct: 661 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 720 Query: 716 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 775 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD Sbjct: 721 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 780 Query: 776 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 835 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV Sbjct: 781 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 840 Query: 836 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 895 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD Sbjct: 841 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 900 Query: 896 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA 955 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA Sbjct: 901 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA 960 Query: 956 FPKHYRPPEGTYGKVET 972 FPKHYRPPEGTYGKVET Sbjct: 961 FPKHYRPPEGTYGKVET 977 >gi|4755140 inositol polyphosphate-4-phosphatase, type 1 isoform a [Homo sapiens] Length = 938 Score = 1833 bits (4749), Expect = 0.0 Identities = 932/977 (95%), Positives = 932/977 (95%), Gaps = 44/977 (4%) Query: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL Sbjct: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60 Query: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY Sbjct: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120 Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180 Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240 Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300 Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360 Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKH-----TSSGCQSIIYIPQDVVRAKEIIAQINT 415 GAPAAHCQGFKSGGLRKKLHKFEETKKH TSSGCQSIIYIPQDVVRAKEIIAQINT Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420 Query: 416 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 475 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD Sbjct: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480 Query: 476 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 535 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC Sbjct: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540 Query: 536 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 595 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK Sbjct: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK--------------------------- 573 Query: 596 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 655 CSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS Sbjct: 574 ------------DCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 621 Query: 656 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 715 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS Sbjct: 622 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 681 Query: 716 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 775 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD Sbjct: 682 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 741 Query: 776 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 835 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV Sbjct: 742 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 801 Query: 836 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 895 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD Sbjct: 802 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 861 Query: 896 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA 955 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA Sbjct: 862 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKA 921 Query: 956 FPKHYRPPEGTYGKVET 972 FPKHYRPPEGTYGKVET Sbjct: 922 FPKHYRPPEGTYGKVET 938 >gi|4504705 inositol polyphosphate-4-phosphatase, type 1 isoform b [Homo sapiens] Length = 954 Score = 1750 bits (4533), Expect = 0.0 Identities = 894/946 (94%), Positives = 895/946 (94%), Gaps = 44/946 (4%) Query: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL Sbjct: 1 MTAREHSPRHGARARAMQRASTIDVAADMLGLSLAGNIQDPDEPILEFSLACSELHTPSL 60 Query: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY Sbjct: 61 DRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQDSLINQMTQVKLSVY 120 Query: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR Sbjct: 121 DVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRVGNITVIGWQMEEKSDQR 180 Query: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG Sbjct: 181 PPVTRSVDTVNGRMVLPVDESLTEALGIRSKYASLRKDTLLKSVFGGAICRMYRFPTTDG 240 Query: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT Sbjct: 241 NHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQT 300 Query: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI Sbjct: 301 IILTYQENLTDLHQYRGPSFKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTI 360 Query: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKH-----TSSGCQSIIYIPQDVVRAKEIIAQINT 415 GAPAAHCQGFKSGGLRKKLHKFEETKKH TSSGCQSIIYIPQDVVRAKEIIAQINT Sbjct: 361 GAPAAHCQGFKSGGLRKKLHKFEETKKHFEECCTSSGCQSIIYIPQDVVRAKEIIAQINT 420 Query: 416 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 475 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD Sbjct: 421 LKTQVSYYAERLSRAAKDRSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARPD 480 Query: 476 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 535 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC Sbjct: 481 YIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLEC 540 Query: 536 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPST 595 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK Sbjct: 541 IIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKK--------------------------- 573 Query: 596 MPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 655 CSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS Sbjct: 574 ------------DCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 621 Query: 656 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 715 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS Sbjct: 622 APTIATYLSLQYRRDVVFCQTLTALICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLS 681 Query: 716 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 775 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD Sbjct: 682 TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFD 741 Query: 776 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 835 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV Sbjct: 742 ALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEV 801 Query: 836 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 895 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD Sbjct: 802 LPEDCLPRSRSQTCLPELLRFLGQNVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKD 861 Query: 896 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNV 941 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRS G R T KN+ Sbjct: 862 RTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSIGTREVVTQKNL 907 >gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105kD [Homo sapiens] Length = 924 Score = 737 bits (1903), Expect = 0.0 Identities = 417/953 (43%), Positives = 584/953 (61%), Gaps = 85/953 (8%) Query: 41 PDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSS 100 P+EP LEF LAC +L P DRK N+ V +SV P + T+++ TEI+EGT +P+FL+ Sbjct: 36 PNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTG 95 Query: 101 IAFFQDSLINQMTQVKLSVYDVKDRSQGTMY-----------------LLGSGTFIVKDL 143 + F + I + T++KL+VYDVKD+S T+ LG +F V +L Sbjct: 96 VTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGEL 155 Query: 144 LQDRHHRLHLTLRSAESDRV-GNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESL 202 L+ + L L+LR+++ +V G I V +M E D + D + L + + Sbjct: 156 LKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHI-TTDVQGQKCALVCECTA 214 Query: 203 TEALGIRSKYASLRKDTL--LKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPR 260 E++ KD L L SV +C++YRFPT+D +RI EQM+ES+LS H+P+ Sbjct: 215 PESVS--------GKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPK 266 Query: 261 QFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSF 320 + + L ++ED R E++ELGELSP W++LR+ ++T ++ YQ+ LT+L + G SF Sbjct: 267 ELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSF 326 Query: 321 KASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLH 380 K+SS K +K LEFVP NLH+QRM+V D YD++T+GAPAAH QGFK+GGLRK LH Sbjct: 327 KSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLH 386 Query: 381 KFEETKKHTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLE 440 +FE +++T G Q I Y P++ +AKE+++ IN L+ ++ +A+ L +A S L+ Sbjct: 387 RFETERRNT--GYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHSPDSLK 444 Query: 441 RTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKA-SPTSTEEEQVMLRNDQDT 499 +L +L++KT V +L+ +++ L ARP I K SP S+ EE DQ Sbjct: 445 NSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSP--QDQPP 502 Query: 500 LMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKERLHGEGCEDVFP 559 +M G++S D+ EEEW++VW NV KSL CII VDKL++++ Sbjct: 503 VMR---GQDSIPH-HSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERD------------ 546 Query: 560 CAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPPPEESSPG 619 G GN D P LT P E Sbjct: 547 --GGSEGSGGNNDGEK--------------------------EPSLTDAIPSHPRE---- 574 Query: 620 EWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTA 679 +W E LYPL+ TL DC+ + ++AK+++ F+L+Q+ A ++ L L RRD+VF Q L Sbjct: 575 DWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAG 634 Query: 680 LICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTF 739 L+CGFIIKL+ L+D GFL+QL+T+GL+ Q+E LLSTY +E+ MLEDM++GI DL+ V F Sbjct: 635 LVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAF 694 Query: 740 KVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGIN 799 K+ +A S+ D+LPVITG R+ + V V LP +F++LP +I+ G LL V PVLFNVGIN Sbjct: 695 KIIEAKSN---DVLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLFNVGIN 751 Query: 800 EQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQ 859 EQQTLAERFGD SLQE IN E+ L Y++ F E +P D + + Q L LL L Q Sbjct: 752 EQQTLAERFGDVSLQESINQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALLENLLQ 811 Query: 860 NVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQV 919 N+ ++K KNV+I+W AA ICR+LNG+RFT CKSAKDRT+MSVTLEQC IL+ EH + Sbjct: 812 NIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQLHKDF 871 Query: 920 FTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHYRPPEGTYGKVET 972 F +AL+CMR EGCR EN +KN+ RKYAFN LQL AFPK+YRPPEGTYGK +T Sbjct: 872 FIRALDCMRREGCRIENVLKNIKCRKYAFNMLQLMAFPKYYRPPEGTYGKADT 924 >gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105kD [Homo sapiens] Length = 924 Score = 737 bits (1903), Expect = 0.0 Identities = 417/953 (43%), Positives = 584/953 (61%), Gaps = 85/953 (8%) Query: 41 PDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSS 100 P+EP LEF LAC +L P DRK N+ V +SV P + T+++ TEI+EGT +P+FL+ Sbjct: 36 PNEPQLEFILACKDLVAPVRDRKLNTLVQISVIHPVEQSLTRYSSTEIVEGTRDPLFLTG 95 Query: 101 IAFFQDSLINQMTQVKLSVYDVKDRSQGTMY-----------------LLGSGTFIVKDL 143 + F + I + T++KL+VYDVKD+S T+ LG +F V +L Sbjct: 96 VTFPSEYPIYEETKIKLTVYDVKDKSHDTVRTSVLPEHKDPPPEVGRSFLGYASFKVGEL 155 Query: 144 LQDRHHRLHLTLRSAESDRV-GNITVIGWQMEEKSDQRPPVTRSVDTVNGRMVLPVDESL 202 L+ + L L+LR+++ +V G I V +M E D + D + L + + Sbjct: 156 LKSKEQLLVLSLRTSDGGKVVGTIEVSVVKMGEIEDGEADHI-TTDVQGQKCALVCECTA 214 Query: 203 TEALGIRSKYASLRKDTL--LKSVFGGAICRMYRFPTTDGNHLRILEQMAESVLSLHVPR 260 E++ KD L L SV +C++YRFPT+D +RI EQM+ES+LS H+P+ Sbjct: 215 PESVS--------GKDNLPFLNSVLKNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPK 266 Query: 261 QFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPSF 320 + + L ++ED R E++ELGELSP W++LR+ ++T ++ YQ+ LT+L + G SF Sbjct: 267 ELISLHIKEDLCRNQEIKELGELSPHWDNLRKNVLTHCDQMVNMYQDILTELSKETGSSF 326 Query: 321 KASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGLRKKLH 380 K+SS K +K LEFVP NLH+QRM+V D YD++T+GAPAAH QGFK+GGLRK LH Sbjct: 327 KSSSSKGEKTLEFVPINLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLH 386 Query: 381 KFEETKKHTSSGCQSIIYIPQDVVRAKEIIAQINTLKTQVSYYAERLSRAAKDRSATGLE 440 +FE +++T G Q I Y P++ +AKE+++ IN L+ ++ +A+ L +A S L+ Sbjct: 387 RFETERRNT--GYQFIYYSPENTAKAKEVLSNINQLQPLIATHADLLLNSASQHSPDSLK 444 Query: 441 RTLAILADKTRQLVTVCDCKLLANSIHGLNAARPDYIASKA-SPTSTEEEQVMLRNDQDT 499 +L +L++KT V +L+ +++ L ARP I K SP S+ EE DQ Sbjct: 445 NSLKMLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPKSSTEESSP--QDQPP 502 Query: 500 LMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECIIQRVDKLLQKERLHGEGCEDVFP 559 +M G++S D+ EEEW++VW NV KSL CII VDKL++++ Sbjct: 503 VMR---GQDSIPH-HSDYDEEEWDRVWANVGKSLNCIIAMVDKLIERD------------ 546 Query: 560 CAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPPPEESSPG 619 G GN D P LT P E Sbjct: 547 --GGSEGSGGNNDGEK--------------------------EPSLTDAIPSHPRE---- 574 Query: 620 EWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTA 679 +W E LYPL+ TL DC+ + ++AK+++ F+L+Q+ A ++ L L RRD+VF Q L Sbjct: 575 DWYEQLYPLILTLKDCMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAG 634 Query: 680 LICGFIIKLRNCLHDDGFLRQLYTIGLLAQFESLLSTYGEELAMLEDMSLGIMDLRNVTF 739 L+CGFIIKL+ L+D GFL+QL+T+GL+ Q+E LLSTY +E+ MLEDM++GI DL+ V F Sbjct: 635 LVCGFIIKLQTSLYDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLKKVAF 694 Query: 740 KVTQATSSASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGIN 799 K+ +A S+ D+LPVITG R+ + V V LP +F++LP +I+ G LL V PVLFNVGIN Sbjct: 695 KIIEAKSN---DVLPVITGRREHYVVEVKLPARMFESLPLQIKEGQLLHVYPVLFNVGIN 751 Query: 800 EQQTLAERFGDTSLQEVINVESLVRLNSYFEQFKEVLPEDCLPRSRSQTCLPELLRFLGQ 859 EQQTLAERFGD SLQE IN E+ L Y++ F E +P D + + Q L LL L Q Sbjct: 752 EQQTLAERFGDVSLQESINQENFELLQEYYKIFMEKMPPDYISHFQEQNDLKALLENLLQ 811 Query: 860 NVHARKNKNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCLILQHEHGMAPQV 919 N+ ++K KNV+I+W AA ICR+LNG+RFT CKSAKDRT+MSVTLEQC IL+ EH + Sbjct: 812 NIQSKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQLHKDF 871 Query: 920 FTQALECMRSEGCRRENTMKNVGSRKYAFNSLQLKAFPKHYRPPEGTYGKVET 972 F +AL+CMR EGCR EN +KN+ RKYAFN LQL AFPK+YRPPEGTYGK +T Sbjct: 872 FIRALDCMRREGCRIENVLKNIKCRKYAFNMLQLMAFPKYYRPPEGTYGKADT 924 >gi|47578115 DEP domain containing 2 isoform a [Homo sapiens] Length = 1606 Score = 124 bits (312), Expect = 3e-28 Identities = 196/877 (22%), Positives = 341/877 (38%), Gaps = 169/877 (19%) Query: 175 EKSDQRPPVTRSVDTVNGRMVLPVDESLTEAL-GIRSKYASLRKDTLLKSVFGGAICRMY 233 +KS +PP + D + ++ +D+ T A+ + ++ SL D + G + Y Sbjct: 769 QKSHSKPPGDEAGDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEY--GVV---Y 823 Query: 234 RFPTTDGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARV---CELEELGELSPC---- 286 + +T G ++E+M E + + ++ L + D V L L E+ P Sbjct: 824 EYDSTAGIKCNVVEKMIEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQS 883 Query: 287 -WESLRRQIVTQYQTIILTYQENLTDLHQYRGPSFKASSLKADK--KLEFVPTNLHIQRM 343 + +L + + I +Y++ L P+FK + K +F PTN H+ M Sbjct: 884 KFSALCSERIEHLCQRISSYKKFSRVLKNRAWPTFKQAKSKISPLHSSDFCPTNCHVNVM 943 Query: 344 R---------------VQDDGGSDQNYD--------------------IVTIGAPAAHCQ 368 VQ D ++D I T+ AP+ Sbjct: 944 EVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSSEQGKLSPMVYIQHTITTMAAPSGLSL 1003 Query: 369 GFKSG-GLRKKLHKFEETKKHTSSGCQSIIYIPQDVVRAKEI-IAQINTLKTQVSYYAER 426 G + G GLR L +E T Q ++ Q ++ E+ + QI+ L + ++Y + + Sbjct: 1004 GQQDGHGLRYLL---KEEDLETQDIYQKLLGKLQTALKEVEMCVCQIDDLLSSITY-SPK 1059 Query: 427 LSRAAKDRSATGLERTLAILADKTRQLVTVC-------------DCKLLANSIHGLNAAR 473 L R +++ G+ T + R VC D +S N+ R Sbjct: 1060 LER----KTSEGIIPTDSDNEKGERNSKRVCFNVAGDEQEDSGHDTISNRDSYSDCNSNR 1115 Query: 474 PDYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSL 533 + IAS S S++ ++ D+ G S+++ +++ + L Sbjct: 1116 -NSIASFTSICSSQCSSYFHSDEMDS------GDELPLSVRISHDKQD------KIHSCL 1162 Query: 534 ECIIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCP 593 E + +VD + L G+ F T +G + Sbjct: 1163 EHLFSQVDSITNL--LKGQAVVRAFDQTKYLTPGRGLQEFQQ------------------ 1202 Query: 594 STMPSTACHPHLTTHCSPPPEESSPGEWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQ 653 P +C L H P W+ L + TL + ++ K ++ L++ Sbjct: 1203 EMEPKLSCPKRLRLHIKQDP-------WN--LPSSVRTLAQNIRKFVEEVKCRLLLALLE 1253 Query: 654 DSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKLR---NCLHDDG-------------F 697 S Q RRD+VFCQTL A +C F +L N + D+ + Sbjct: 1254 YSDS------ETQLRRDMVFCQTLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRW 1307 Query: 698 LRQLYTIGLLAQFESLLS-TYGEELAMLEDMSLGIMDLRNVTFKVTQATSSASADMLPVI 756 L Q+ G+L F+SLLS +E AMLED + + DL V+F + +P+ Sbjct: 1308 LDQIANAGVLFHFQSLLSPNLTDEQAMLEDTLVALFDLEKVSFYFKPSEEEPLVANVPLT 1367 Query: 757 ---TGNRDGFNVRVPLPGPLFDALPREIQSGMLLRVQPVLFNVGINEQQTLAERFGDTSL 813 G+R V + F+ LP+ +++G ++ PVLF + + R + S+ Sbjct: 1368 YQAEGSRQALKVYFYIDSYHFEQLPQRLKNGGGFKIHPVLFAQALESMEGYYYR-DNVSV 1426 Query: 814 QEV---INVESLVRLNSYFEQFKEVLPE--DCLPRSRSQTC-----------LPELLRFL 857 +E IN SL ++ Y ++ + + + P S S+ L EL R + Sbjct: 1427 EEFQAQINAASLEKVKQYNQKLRAFYLDKSNSPPNSTSKAAYVDKLMRPLNALDELYRLV 1486 Query: 858 GQNVHARKN----------KNVDILWQAAEICRRLNGVRFTSCKSAKDRTAMSVTLEQCL 907 + +++ V +L ++E+C RL C S R +SVTLEQ + Sbjct: 1487 ASFIRSKRTAACANTACSASGVGLLSVSSELCNRLGACHIIMCSSGVHRCTLSVTLEQAI 1546 Query: 908 ILQHEHGMAPQVFTQALECMRSEGCRRENTMKNVGSR 944 IL HG+ P+ QA + MR +G R +NT KN+G R Sbjct: 1547 ILARSHGLPPRYIMQATDVMRKQGARVQNTAKNLGVR 1583 >gi|34452732 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 [Homo sapiens] Length = 1659 Score = 120 bits (300), Expect = 8e-27 Identities = 101/352 (28%), Positives = 157/352 (44%), Gaps = 45/352 (12%) Query: 629 LTTLTDCVAMMSDKAKKAMVFLLMQDSAPTIATYLSLQYRRDVVFCQTLTALICGFIIKL 688 + TL D + + K ++ L++ T LQ RRD +FCQ L A +C F +L Sbjct: 1289 IKTLVDNIQRYVEDGKNQLLLALLK------CTDTELQLRRDAIFCQALVAAVCTFSEQL 1342 Query: 689 RNCL----HDDG------------FLRQLYTIGLLAQFESLLS--TYGEELAMLEDMSLG 730 L +++G +L Q+ G+L +SLLS T EE MLED+ + Sbjct: 1343 LAALGYRYNNNGEYEESSRDASRKWLEQVAATGVLLHCQSLLSPATVKEERTMLEDIWVT 1402 Query: 731 IMDLRNVTFKVTQATSS--ASADMLPVITGNRDGFNVRVPLPGPLFDALPREIQSGMLLR 788 + +L NVTF Q + A+ ++ I G+R V L F LP ++ G LR Sbjct: 1403 LSELDNVTFSFKQLDENYVANTNVFYHIEGSRQALKVIFYLDSYHFSKLPSRLEGGASLR 1462 Query: 789 VQPVLFNVGINEQQTLAERFGDTS--LQEVINVESLVRLNSYFEQFKEV-LPEDCLPRSR 845 + LF + + L + LQ+ IN +SL ++ Y+ + + L LP Sbjct: 1463 LHTALFTKVLENVEGLPSPGSQAAEDLQQDINAQSLEKVQQYYRKLRAFYLERSNLPTDA 1522 Query: 846 SQTC------------LPELLRFLGQNVH----ARKNKNVDILWQAAEICRRLNGVRFTS 889 S T L EL R + VH A + ++ ++E+C RL + Sbjct: 1523 STTAVKIDQLIRPINALDELCRLMKSFVHPKPGAAGSVGAGLIPISSELCYRLGACQMVM 1582 Query: 890 CKSAKDRTAMSVTLEQCLILQHEHGMAPQVFTQALECMRSEGCRRENTMKNV 941 C + R+ +SV+LEQ IL HG+ P+ QA + MR +G R E KN+ Sbjct: 1583 CGTGMQRSTLSVSLEQAAILARSHGLLPKCIMQATDIMRKQGPRVEILAKNL 1634 Score = 32.7 bits (73), Expect = 1.7 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 10/124 (8%) Query: 232 MYRFPTTDGNHLRILEQMAESVLSLHVPRQFVKLLLEEDAARVCELEELGELSPCWESL- 290 +Y + +T G +LE++ E + + ++ D+ V L LS ++ Sbjct: 856 VYEYVSTAGVRCHVLEKIVEPRGCFGLTAKILEAFAANDSVFVENCRRLMALSSAIVTMP 915 Query: 291 ----RRQIVTQYQTI---ILTYQENLTDLHQYRGPSFKASSLKADKK--LEFVPTNLHIQ 341 R T+ ++I I YQE L P FK + L+ L+F PTN HI Sbjct: 916 HFEFRNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEPHPLCGLDFCPTNCHIN 975 Query: 342 RMRV 345 M V Sbjct: 976 LMEV 979 >gi|88703066 copine-like protein [Homo sapiens] Length = 553 Score = 36.2 bits (82), Expect = 0.15 Identities = 27/135 (20%), Positives = 53/135 (39%), Gaps = 4/135 (2%) Query: 46 LEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQ 105 +E +++C L K + V + + W + +TE+I+ T NP F+ F Sbjct: 16 IEITVSCRNLLDLDTFSKSDPMVVLYTQSRASQEWREFGRTEVIDNTLNPDFVRK--FVL 73 Query: 106 DSLINQMTQVKLSVYDV--KDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAESDRV 163 D + ++ VY+V K LG + +++ + R+ TL + Sbjct: 74 DYFFEEKQNLRFDVYNVDSKTNISKPKDFLGQAFLALGEVIGGQGSRVERTLTGVPGKKC 133 Query: 164 GNITVIGWQMEEKSD 178 G I + ++ D Sbjct: 134 GTILLTAEELSNCRD 148 >gi|25141328 copine 7 isoform a [Homo sapiens] Length = 558 Score = 35.4 bits (80), Expect = 0.26 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 8/88 (9%) Query: 36 GNIQDPDEPILEFSLACSELHTPSLDRKP--NSFVAVSVTTPPQAFWTKHAQTEIIEGTN 93 G + P +E L+C L LDR P S +V++ Q W + +TE++ + Sbjct: 14 GGLPAPCASKVELRLSCRHL----LDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSL 69 Query: 94 NPIFLSSIAFFQDSLINQMTQVKLSVYD 121 +P+F S F D ++ +++ VYD Sbjct: 70 HPVF--SKVFTVDYYFEEVQRLRFEVYD 95 >gi|7656993 copine 7 isoform b [Homo sapiens] Length = 633 Score = 35.4 bits (80), Expect = 0.26 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 8/88 (9%) Query: 36 GNIQDPDEPILEFSLACSELHTPSLDRKP--NSFVAVSVTTPPQAFWTKHAQTEIIEGTN 93 G + P +E L+C L LDR P S +V++ Q W + +TE++ + Sbjct: 14 GGLPAPCASKVELRLSCRHL----LDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSL 69 Query: 94 NPIFLSSIAFFQDSLINQMTQVKLSVYD 121 +P+F S F D ++ +++ VYD Sbjct: 70 HPVF--SKVFTVDYYFEEVQRLRFEVYD 95 >gi|25141323 copine V [Homo sapiens] Length = 593 Score = 35.0 bits (79), Expect = 0.34 Identities = 23/94 (24%), Positives = 41/94 (43%), Gaps = 5/94 (5%) Query: 33 SLAGNIQDPDEPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGT 92 SLAG+I +E +++C L + K + + W + +TE+I+ T Sbjct: 15 SLAGSIPATK---VEITVSCRNLLDKDMFSKSDPLCVMYTQGMENKQWREFGRTEVIDNT 71 Query: 93 NNPIFLSSIAFFQDSLINQMTQVKLSVYDVKDRS 126 NP F+ F D + ++ +YDV +S Sbjct: 72 LNPDFVRK--FIVDYFFEEKQNLRFDLYDVDSKS 103 >gi|226498192 atonal homolog 8 [Homo sapiens] Length = 321 Score = 33.9 bits (76), Expect = 0.76 Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 5/63 (7%) Query: 569 GNPDSHAY---WIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPP--PEESSPGEWSE 623 G P++ + +RP C P+ P PS P+ P T +PP P ESS S Sbjct: 138 GGPEAQPFREPGLRPRILLCAPPARPAPSAPPAPPAPPESTVRPAPPTRPGESSYSSISH 197 Query: 624 ALY 626 +Y Sbjct: 198 VIY 200 >gi|126090909 engrailed homeobox 1 [Homo sapiens] Length = 392 Score = 33.9 bits (76), Expect = 0.76 Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 3/54 (5%) Query: 562 GSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPPPEE 615 G+ S D + + P+ P++PC +P A HPHL H PPP + Sbjct: 34 GASGSSGSGSDGDSVPVSPQPAPPSPPAAPC---LPPLAHHPHLPPHPPPPPPQ 84 >gi|25121972 copine VIII [Homo sapiens] Length = 564 Score = 33.9 bits (76), Expect = 0.76 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 2/81 (2%) Query: 46 LEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIAFFQ 105 +E S++C L K + + V W + +TE+I+ T NP F+ F Sbjct: 26 VEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRK--FIL 83 Query: 106 DSLINQMTQVKLSVYDVKDRS 126 D + ++ +YDV +S Sbjct: 84 DYFFEERENLRFDLYDVDSKS 104 >gi|169201827 PREDICTED: similar to hCG1798126 [Homo sapiens] Length = 269 Score = 33.5 bits (75), Expect = 0.99 Identities = 25/57 (43%), Positives = 27/57 (47%), Gaps = 8/57 (14%) Query: 583 PF-CDVPSS-PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 635 PF C +P P P T PS A +P L T HC P P S S A YP L T C Sbjct: 113 PFLCTLPHCFPLPGTSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 165 Score = 32.7 bits (73), Expect = 1.7 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 6/47 (12%) Query: 591 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 635 P P+T PS A +P L T HC P P S S A YP L T C Sbjct: 145 PLPATSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 187 Score = 31.6 bits (70), Expect = 3.8 Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 6/44 (13%) Query: 591 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTL 632 P P T PS A +P L T HC P P S S A YP L TL Sbjct: 189 PLPGTSPSCARYPFLCTSPHCFPLPGTSP----SCARYPFLCTL 228 >gi|169201475 PREDICTED: similar to hCG1798126, partial [Homo sapiens] Length = 190 Score = 33.5 bits (75), Expect = 0.99 Identities = 25/57 (43%), Positives = 27/57 (47%), Gaps = 8/57 (14%) Query: 583 PF-CDVPSS-PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 635 PF C +P P P T PS A +P L T HC P P S S A YP L T C Sbjct: 34 PFLCTLPHCFPLPGTSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 86 Score = 32.7 bits (73), Expect = 1.7 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 6/47 (12%) Query: 591 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 635 P P+T PS A +P L T HC P P S S A YP L T C Sbjct: 66 PLPATSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 108 Score = 31.6 bits (70), Expect = 3.8 Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 6/44 (13%) Query: 591 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTL 632 P P T PS A +P L T HC P P S S A YP L TL Sbjct: 110 PLPGTSPSCARYPFLCTSPHCFPLPGTSP----SCARYPFLCTL 149 >gi|169190743 PREDICTED: similar to hCG1798126 [Homo sapiens] Length = 269 Score = 33.5 bits (75), Expect = 0.99 Identities = 25/57 (43%), Positives = 27/57 (47%), Gaps = 8/57 (14%) Query: 583 PF-CDVPSS-PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 635 PF C +P P P T PS A +P L T HC P P S S A YP L T C Sbjct: 113 PFLCTLPHCFPLPGTSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 165 Score = 32.7 bits (73), Expect = 1.7 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 6/47 (12%) Query: 591 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTLTDC 635 P P+T PS A +P L T HC P P S S A YP L T C Sbjct: 145 PLPATSPSCARYPFLCTSPHCFPLPATSP----SCARYPFLCTSPHC 187 Score = 31.6 bits (70), Expect = 3.8 Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 6/44 (13%) Query: 591 PCPSTMPSTACHPHLTT--HCSPPPEESSPGEWSEALYPLLTTL 632 P P T PS A +P L T HC P P S S A YP L TL Sbjct: 189 PLPGTSPSCARYPFLCTSPHCFPLPGTSP----SCARYPFLCTL 228 >gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens] Length = 1113 Score = 33.1 bits (74), Expect = 1.3 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 19/100 (19%) Query: 477 IASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECI 536 +A + P ST+ +L L R GR+S +L+ W EE E + Sbjct: 802 MAPASGPASTDAVSALLEQTAVELEKRQEGRSSTQTLEDSWRYEE--------TSENEAV 853 Query: 537 IQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAY 576 + ++ +++E EG EDVF ++K +PD Y Sbjct: 854 AEEEEEEVEEE----EGEEDVF-------TEKASPDMDGY 882 >gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens] Length = 1118 Score = 33.1 bits (74), Expect = 1.3 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 19/100 (19%) Query: 477 IASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECI 536 +A + P ST+ +L L R GR+S +L+ W EE E + Sbjct: 802 MAPASGPASTDAVSALLEQTAVELEKRQEGRSSTQTLEDSWRYEE--------TSENEAV 853 Query: 537 IQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAY 576 + ++ +++E EG EDVF ++K +PD Y Sbjct: 854 AEEEEEEVEEE----EGEEDVF-------TEKASPDMDGY 882 >gi|242247251 WW and C2 domain containing 1 isoform 1 [Homo sapiens] Length = 1119 Score = 33.1 bits (74), Expect = 1.3 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 19/100 (19%) Query: 477 IASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLECI 536 +A + P ST+ +L L R GR+S +L+ W EE E + Sbjct: 802 MAPASGPASTDAVSALLEQTAVELEKRQEGRSSTQTLEDSWRYEE--------TSENEAV 853 Query: 537 IQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAY 576 + ++ +++E EG EDVF ++K +PD Y Sbjct: 854 AEEEEEEVEEE----EGEEDVF-------TEKASPDMDGY 882 >gi|126116565 MYC binding protein 2 [Homo sapiens] Length = 4640 Score = 33.1 bits (74), Expect = 1.3 Identities = 38/137 (27%), Positives = 63/137 (45%), Gaps = 24/137 (17%) Query: 201 SLTEALGIRSKYASLRKDTLLKSVFGGAICRM-YRFPTTDGNHLRILEQMAESVLSLHVP 259 S+T G+ ++ S +K V G I ++ YR PT+DG+ + +Q +E V H+ Sbjct: 1313 SITTDDGVVFQFKSSKKSNNGTDVNAGQIPQLLYRLPTSDGSASKGKQQTSEPV---HI- 1368 Query: 260 RQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPS 319 L+ AR +E C+ESL + + T++L +E L +G Sbjct: 1369 -------LKRSFARTVSVE-------CFESLLSILHWSWTTLVLGVEE----LRGLKGFQ 1410 Query: 320 FKASSLKADKKLEFVPT 336 F A+ L + +L FV T Sbjct: 1411 FTATLLDLE-RLRFVGT 1426 >gi|34304360 nephrocystin 3 [Homo sapiens] Length = 1330 Score = 32.7 bits (73), Expect = 1.7 Identities = 26/116 (22%), Positives = 53/116 (45%), Gaps = 13/116 (11%) Query: 260 RQFVKLLLEEDAARVCELEELGELSPCWESLRRQIVTQYQTIILTYQENLTDLHQYRGPS 319 + + K+L E+++A + + + E + +E R ++ Q++ T + + DL Sbjct: 135 KTYQKILREKESALEAKYQAM-ERAATFEHDRDKVKRQFKIFRETKENEIQDL------- 186 Query: 320 FKASSLKADKKLEFVPTNLHIQRMRVQDDGGSDQNYDIVTIGAPAAHCQGFKSGGL 375 L+A ++LE L Q ++V D G SD + + + A C+ + G L Sbjct: 187 -----LRAKRELESKLQRLQAQGIQVFDPGESDSDDNCTDVTAAGTQCEYWTGGAL 237 >gi|116268109 nucleotide-binding oligomerization domains 27 [Homo sapiens] Length = 1866 Score = 32.7 bits (73), Expect = 1.7 Identities = 29/111 (26%), Positives = 55/111 (49%), Gaps = 11/111 (9%) Query: 249 MAESVLSLHVPRQFVKLLLEEDAARVCELE-ELGELSPCWESLRRQIVTQYQTIILTYQE 307 MAE+ LH+ R KL L ++ V + L +S CW I Q++T+I + + Sbjct: 890 MAEAASQLHIAR---KLDLSDNGLSVAGVHCVLRAVSACWTLAELHISLQHKTVIFMFAQ 946 Query: 308 NLTDLHQYRGPSFKASSLKADKKLEFVPTNLHI--QRMRVQDDGGSDQNYD 356 + + +GP +A+ L D + +P+ L + +RMR+ G +++ + Sbjct: 947 ---EPEEQKGPQERAAFL--DSLMLQMPSELPLSSRRMRLTHCGLQEKHLE 992 >gi|28875784 armadillo repeat containing 5 isoform b [Homo sapiens] Length = 725 Score = 32.3 bits (72), Expect = 2.2 Identities = 20/42 (47%), Positives = 22/42 (52%), Gaps = 8/42 (19%) Query: 583 PFCDVPSSPCPSTMPSTACHPHLTTHCSP---PPEESSPGEW 621 P C+ PSSP S P PHL TH S PP+ SP EW Sbjct: 632 PPCESPSSPMASMGP----EPHLPTHLSSPARPPDNLSP-EW 668 >gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Homo sapiens] Length = 1194 Score = 31.6 bits (70), Expect = 3.8 Identities = 31/141 (21%), Positives = 59/141 (41%), Gaps = 17/141 (12%) Query: 416 LKTQVSYYAERLSRAAKD-RSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARP 474 ++ Q++ +RL + R+ L+ +++L ++ RQLV+ + A+ I+ + Sbjct: 105 IREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKNQRAASQINVCGVRKR 164 Query: 475 DYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLE 534 Y A AS + EQ+ R S L +D+ EEE E V + + E Sbjct: 165 SYSAGNAS----QLEQLS------------RARRSGGELYIDYEEEEMETVEQSTQRIKE 208 Query: 535 CIIQRVDKLLQKERLHGEGCE 555 D ++++ CE Sbjct: 209 FRQLTADMQALEQKIQDSSCE 229 >gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Homo sapiens] Length = 1352 Score = 31.6 bits (70), Expect = 3.8 Identities = 31/141 (21%), Positives = 59/141 (41%), Gaps = 17/141 (12%) Query: 416 LKTQVSYYAERLSRAAKD-RSATGLERTLAILADKTRQLVTVCDCKLLANSIHGLNAARP 474 ++ Q++ +RL + R+ L+ +++L ++ RQLV+ + A+ I+ + Sbjct: 263 IREQMAIALKRLKELEEQVRTIPVLQVKISVLQEEKRQLVSQLKNQRAASQINVCGVRKR 322 Query: 475 DYIASKASPTSTEEEQVMLRNDQDTLMARWTGRNSRSSLQVDWHEEEWEKVWLNVDKSLE 534 Y A AS + EQ+ R S L +D+ EEE E V + + E Sbjct: 323 SYSAGNAS----QLEQLS------------RARRSGGELYIDYEEEEMETVEQSTQRIKE 366 Query: 535 CIIQRVDKLLQKERLHGEGCE 555 D ++++ CE Sbjct: 367 FRQLTADMQALEQKIQDSSCE 387 >gi|38201677 teashirt family zinc finger 1 [Homo sapiens] Length = 1032 Score = 31.6 bits (70), Expect = 3.8 Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 2/96 (2%) Query: 561 AGSCTSKKGNPDSHAYWIRPEDPFCDVPSSPCPSTMPSTACHPHLTTHCSPPPEESSPG- 619 +GS TS + P P C V ++ ++ PST+C T+H S SS G Sbjct: 94 SGSTTSTNDASQKESSAPTPTPPTCPVSTTGPTTSTPSTSCSSS-TSHSSTTSTSSSSGY 152 Query: 620 EWSEALYPLLTTLTDCVAMMSDKAKKAMVFLLMQDS 655 +W +A T ++ + + + V L Q++ Sbjct: 153 DWHQAALAKTLQQTSSYGLLPEPSLFSTVQLYRQNN 188 >gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo sapiens] Length = 1425 Score = 30.8 bits (68), Expect = 6.4 Identities = 25/104 (24%), Positives = 40/104 (38%), Gaps = 9/104 (8%) Query: 525 VWLNVDKSLECIIQRVDKLLQKERLHGEGCEDVFPCAGSCTSKKGNPDSHAYWIRPEDPF 584 VW+ ++ C+ K R H C VF CA C+ K Y R E Sbjct: 695 VWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVF-CASCCSLKC----KLLYMDRKEARV 749 Query: 585 CDVPSSPCPSTMPSTACHPHLTTHCSPPPEESSPGEWSEALYPL 628 C + C S + + ++ + S P ++P E+ + PL Sbjct: 750 CVI----CHSVLMNAQAWENMMSASSQSPNPNNPAEYCSTIPPL 789 >gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo sapiens] Length = 1236 Score = 30.4 bits (67), Expect = 8.4 Identities = 31/143 (21%), Positives = 58/143 (40%), Gaps = 22/143 (15%) Query: 43 EPILEFSLACSELHTPSLDRKPNSFVAVSVTTPPQAFWTKHAQTEIIEGTNNPIFLSSIA 102 E +LE T + + F+ V+VT A KH Q + + +I Sbjct: 880 EQLLENVCLLLASRTRDVVKSALGFIKVAVTVMDVAHLAKHVQ----------LVMEAIG 929 Query: 103 FFQDSLINQMTQVKLSVYDVKDRSQGTMYLLGSGTFIVKDLLQDRHHRLHLTLRSAES-- 160 D + + +K R+ T ++ G +VK LL + +HR+ + +R AE+ Sbjct: 930 KLSDDMRRH--------FRMKLRNLFTKFIRKFGFELVKRLLPEEYHRVLVNIRKAEARA 981 Query: 161 --DRVGNITVIGWQMEEKSDQRP 181 R + + + EE+ ++ P Sbjct: 982 KRHRALSQAAVEEEEEEEEEEEP 1004 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.133 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,735,665 Number of Sequences: 37866 Number of extensions: 1673226 Number of successful extensions: 5077 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 10 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 5025 Number of HSP's gapped (non-prelim): 51 length of query: 972 length of database: 18,247,518 effective HSP length: 112 effective length of query: 860 effective length of database: 14,006,526 effective search space: 12045612360 effective search space used: 12045612360 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.