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Search of human proteins with 196114951
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|196114951 protein tyrosine phosphatase, non-receptor type 12
isoform 1 [Homo sapiens]
(780 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|196114951 protein tyrosine phosphatase, non-receptor type 12 ... 1605 0.0
gi|196114967 protein tyrosine phosphatase, non-receptor type 12 ... 1365 0.0
gi|196114970 protein tyrosine phosphatase, non-receptor type 12 ... 1343 0.0
gi|224586931 protein tyrosine phosphatase, non-receptor type 22 ... 425 e-119
gi|224586929 protein tyrosine phosphatase, non-receptor type 22 ... 425 e-119
gi|18375655 protein tyrosine phosphatase, non-receptor type 18 i... 273 6e-73
gi|148539860 protein tyrosine phosphatase, receptor type, T isof... 199 1e-50
gi|148539858 protein tyrosine phosphatase, receptor type, T isof... 199 1e-50
gi|18104993 protein tyrosine phosphatase, non-receptor type 6 is... 194 3e-49
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo... 192 1e-48
gi|157419150 protein tyrosine phosphatase, receptor type, M isof... 190 4e-48
gi|157419152 protein tyrosine phosphatase, receptor type, M isof... 190 4e-48
gi|18104989 protein tyrosine phosphatase, non-receptor type 6 is... 189 1e-47
gi|18104991 protein tyrosine phosphatase, non-receptor type 6 is... 189 1e-47
gi|148728162 protein tyrosine phosphatase, receptor type, J isof... 186 5e-47
gi|208431815 protein tyrosine phosphatase, receptor type, K isof... 185 1e-46
gi|241896926 protein tyrosine phosphatase, receptor type, H isof... 184 4e-46
gi|241896924 protein tyrosine phosphatase, receptor type, H isof... 184 4e-46
gi|13677222 receptor-type protein tyrosine phosphatase O isoform... 183 6e-46
gi|13677220 receptor-type protein tyrosine phosphatase O isoform... 183 6e-46
gi|13677218 receptor-type protein tyrosine phosphatase O isoform... 183 6e-46
gi|13677216 receptor-type protein tyrosine phosphatase O isoform... 183 6e-46
gi|13677214 receptor-type protein tyrosine phosphatase O isoform... 183 6e-46
gi|4506323 receptor-type protein tyrosine phosphatase O isoform ... 183 6e-46
gi|33356177 protein tyrosine phosphatase, non-receptor type 11 [... 180 4e-45
gi|18450371 protein tyrosine phosphatase, receptor type, A isofo... 180 4e-45
gi|4506303 protein tyrosine phosphatase, receptor type, A isofor... 180 4e-45
gi|18450369 protein tyrosine phosphatase, receptor type, A isofo... 180 4e-45
gi|4506301 protein tyrosine phosphatase, non-receptor type 9 [Ho... 179 7e-45
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p... 177 3e-44
>gi|196114951 protein tyrosine phosphatase, non-receptor type 12
isoform 1 [Homo sapiens]
Length = 780
Score = 1605 bits (4157), Expect = 0.0
Identities = 780/780 (100%), Positives = 780/780 (100%)
Query: 1 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK 60
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK
Sbjct: 1 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK 60
Query: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM
Sbjct: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
Query: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL 180
IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL
Sbjct: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL 180
Query: 181 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA 240
EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA
Sbjct: 181 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA 240
Query: 241 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL 300
ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL
Sbjct: 241 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL 300
Query: 301 YEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPH 360
YEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPH
Sbjct: 301 YEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPH 360
Query: 361 PVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNE 420
PVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNE
Sbjct: 361 PVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNE 420
Query: 421 STIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQE 480
STIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQE
Sbjct: 421 STIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQE 480
Query: 481 LSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHG 540
LSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHG
Sbjct: 481 LSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHG 540
Query: 541 PENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNP 600
PENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNP
Sbjct: 541 PENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNP 600
Query: 601 LHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTH 660
LHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTH
Sbjct: 601 LHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTH 660
Query: 661 SGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSE 720
SGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSE
Sbjct: 661 SGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSE 720
Query: 721 NEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT 780
NEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
Sbjct: 721 NEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT 780
>gi|196114967 protein tyrosine phosphatase, non-receptor type 12
isoform 2 [Homo sapiens]
Length = 661
Score = 1365 bits (3533), Expect = 0.0
Identities = 661/661 (100%), Positives = 661/661 (100%)
Query: 120 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 179
MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL
Sbjct: 1 MIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLL 60
Query: 180 LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG 239
LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG
Sbjct: 61 LEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTG 120
Query: 240 AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 299
AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ
Sbjct: 121 AICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 180
Query: 300 LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP 359
LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP
Sbjct: 181 LYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEP 240
Query: 360 HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN 419
HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN
Sbjct: 241 HPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKN 300
Query: 420 ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ 479
ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ
Sbjct: 301 ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ 360
Query: 480 ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH 539
ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH
Sbjct: 361 ELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFH 420
Query: 540 GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN 599
GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN
Sbjct: 421 GPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTN 480
Query: 600 PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT 659
PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT
Sbjct: 481 PLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTT 540
Query: 660 HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS 719
HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS
Sbjct: 541 HSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITS 600
Query: 720 ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW 779
ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW
Sbjct: 601 ENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW 660
Query: 780 T 780
T
Sbjct: 661 T 661
>gi|196114970 protein tyrosine phosphatase, non-receptor type 12
isoform 3 [Homo sapiens]
Length = 650
Score = 1343 bits (3475), Expect = 0.0
Identities = 650/650 (100%), Positives = 650/650 (100%)
Query: 131 MACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLY 190
MACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLY
Sbjct: 1 MACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLY 60
Query: 191 QFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNL 250
QFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNL
Sbjct: 61 QFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNL 120
Query: 251 LKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIA 310
LKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIA
Sbjct: 121 LKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIA 180
Query: 311 DGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSP 370
DGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSP
Sbjct: 181 DGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSP 240
Query: 371 PSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKL 430
PSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKL
Sbjct: 241 PSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKL 300
Query: 431 ERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQELSSDLNVGDT 490
ERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQELSSDLNVGDT
Sbjct: 301 ERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQELSSDLNVGDT 360
Query: 491 SQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDL 550
SQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDL
Sbjct: 361 SQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDL 420
Query: 551 SEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDE 610
SEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDE
Sbjct: 421 SEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDE 480
Query: 611 RNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVS 670
RNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVS
Sbjct: 481 RNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVS 540
Query: 671 EDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGG 730
EDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGG
Sbjct: 541 EDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGG 600
Query: 731 IHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT 780
IHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
Sbjct: 601 IHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT 650
>gi|224586931 protein tyrosine phosphatase, non-receptor type 22
(lymphoid) isoform 2 [Homo sapiens]
Length = 691
Score = 425 bits (1093), Expect = e-119
Identities = 277/718 (38%), Positives = 383/718 (53%), Gaps = 116/718 (16%)
Query: 1 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK 60
M+Q EIL+KF+ Q+ K ++ FA +F++L+R STKY+ +K YPT EK +N+K
Sbjct: 1 MDQREILQKFLDEAQSKKIT----KEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIK 56
Query: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
KNRYKDILP+D+SRV+L+L T +DS YINANFIKGVYGPKAY+ATQGPL+ T++DFWRM
Sbjct: 57 KNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRM 116
Query: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL 180
IWEY+V+IIVMAC E+EMG+KKCERYW GE + F PF +SCE E+ ++DY IRTL +
Sbjct: 117 IWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKV 176
Query: 181 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA 240
+F +E+R +YQFHY NWPDHDVPSS D IL++I +R YQE + VPICIHCSAGCGRTG
Sbjct: 177 KFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGV 236
Query: 241 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL 300
ICAIDYTW LLK G IPE F+VF+LI+EMRTQR S VQT+EQYELV+ A+ +LF++Q+ +
Sbjct: 237 ICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDV 296
Query: 301 YEIHGAQKIADGVNEINTENMVSSIEPEKQ-----DSPPPKPPRTRS----CLVEGDAKE 351
I D TE+ PEK DS P P++ + + + K
Sbjct: 297 --------IRD--KHSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKM 346
Query: 352 EILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSK 411
EI + S+F T+ + VLH S L NYS
Sbjct: 347 EIKE---------------SSSFDFRTSEISAKEEL----VLHPAKSSTSFDFLELNYS- 386
Query: 412 STELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGP----KSFDGNTLLNRGHAIKIKSA 467
DK + + ++ K P+ P +S D +LL G
Sbjct: 387 --------------FDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEG-------- 424
Query: 468 SPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLP 527
C SKP +N NS V + T+S TP E Q +T
Sbjct: 425 --C---SNSKP------VNAAGRYFNSKVPITRTKS-----TPFELIQQRETK------E 462
Query: 528 LDEKGHVTWSFHGPENA----IPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVD 583
+D K + ++ P ++ + + +S+++NY SL Q+ V
Sbjct: 463 VDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNY------SLPYDSKHQIRNASNVK 516
Query: 584 HDNTS--------PLFRTPLSFTNPLHSDDSDSD---ERNSDGAVTQNKTNISTASATVS 632
H ++S PL P + P S DG V + +++++ S
Sbjct: 517 HHDSSALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFS 576
Query: 633 AATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASE 690
S +S+S +S + + + + ++ PPPLP RTPESF++ E
Sbjct: 577 YYNSHDSLSLNSPTNISSLLNQESAVLATAPR----IDDEIPPPLPVRTPESFIVVEE 630
>gi|224586929 protein tyrosine phosphatase, non-receptor type 22
(lymphoid) isoform 1 [Homo sapiens]
Length = 807
Score = 425 bits (1093), Expect = e-119
Identities = 277/718 (38%), Positives = 383/718 (53%), Gaps = 116/718 (16%)
Query: 1 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK 60
M+Q EIL+KF+ Q+ K ++ FA +F++L+R STKY+ +K YPT EK +N+K
Sbjct: 1 MDQREILQKFLDEAQSKKIT----KEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIK 56
Query: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
KNRYKDILP+D+SRV+L+L T +DS YINANFIKGVYGPKAY+ATQGPL+ T++DFWRM
Sbjct: 57 KNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRM 116
Query: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL 180
IWEY+V+IIVMAC E+EMG+KKCERYW GE + F PF +SCE E+ ++DY IRTL +
Sbjct: 117 IWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKV 176
Query: 181 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA 240
+F +E+R +YQFHY NWPDHDVPSS D IL++I +R YQE + VPICIHCSAGCGRTG
Sbjct: 177 KFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGV 236
Query: 241 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL 300
ICAIDYTW LLK G IPE F+VF+LI+EMRTQR S VQT+EQYELV+ A+ +LF++Q+ +
Sbjct: 237 ICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDV 296
Query: 301 YEIHGAQKIADGVNEINTENMVSSIEPEKQ-----DSPPPKPPRTRS----CLVEGDAKE 351
I D TE+ PEK DS P P++ + + + K
Sbjct: 297 --------IRD--KHSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKM 346
Query: 352 EILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSK 411
EI + S+F T+ + VLH S L NYS
Sbjct: 347 EIKE---------------SSSFDFRTSEISAKEEL----VLHPAKSSTSFDFLELNYS- 386
Query: 412 STELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGP----KSFDGNTLLNRGHAIKIKSA 467
DK + + ++ K P+ P +S D +LL G
Sbjct: 387 --------------FDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSLLFEG-------- 424
Query: 468 SPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLP 527
C SKP +N NS V + T+S TP E Q +T
Sbjct: 425 --C---SNSKP------VNAAGRYFNSKVPITRTKS-----TPFELIQQRETK------E 462
Query: 528 LDEKGHVTWSFHGPENA----IPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVD 583
+D K + ++ P ++ + + +S+++NY SL Q+ V
Sbjct: 463 VDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNY------SLPYDSKHQIRNASNVK 516
Query: 584 HDNTS--------PLFRTPLSFTNPLHSDDSDSD---ERNSDGAVTQNKTNISTASATVS 632
H ++S PL P + P S DG V + +++++ S
Sbjct: 517 HHDSSALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFS 576
Query: 633 AATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASE 690
S +S+S +S + + + + ++ PPPLP RTPESF++ E
Sbjct: 577 YYNSHDSLSLNSPTNISSLLNQESAVLATAPR----IDDEIPPPLPVRTPESFIVVEE 630
Score = 59.3 bits (142), Expect = 1e-08
Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 14/116 (12%)
Query: 674 PPPLPERTPESFVLASE----------HNTPVRSEWSELQSQERSEQKKSEGLITSENEK 723
PPPLPERT ESF LA E ++T S +++ + + S++ K
Sbjct: 694 PPPLPERTLESFFLADEDCMQAQSIETYSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLK 753
Query: 724 CDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEW 779
+ +C CPP + Q S N + + GF NR KPKGPR+PP W
Sbjct: 754 I---LRNMKKSICNSCPPNKPAESVQ-SNNSSSFLNFGFANRFSKPKGPRNPPPTW 805
>gi|18375655 protein tyrosine phosphatase, non-receptor type 18
isoform 1 [Homo sapiens]
Length = 460
Score = 273 bits (697), Expect = 6e-73
Identities = 132/295 (44%), Positives = 193/295 (65%), Gaps = 9/295 (3%)
Query: 8 RKFIQRVQAMKSPDHNGEDN--FARDFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYK 65
R F++R++A G + A +F ++ S ++ + + T G + ENV+KNRYK
Sbjct: 9 RSFLERLEA-----RGGREGAVLAGEFSDIQACSAAWKADGVCSTVAGSRPENVRKNRYK 63
Query: 66 DILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYN 125
D+LP+D +RV L+L SDYIN NFI+GV G AY+ATQGPL +T++DFWR++WE+
Sbjct: 64 DVLPYDQTRVILSLLQEEGHSDYINGNFIRGVDGSLAYIATQGPLPHTLLDFWRLVWEFG 123
Query: 126 VVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKIS-CEDEQARTDYFIRTLLLEFQN 184
V +I+MACRE E GRK+CERYW ++P+ F I+ +++ D +RTL + FQ
Sbjct: 124 VKVILMACREIENGRKRCERYW-AQEQEPLQTGLFCITLIKEKWLNEDIMLRTLKVTFQK 182
Query: 185 ESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAI 244
ESR +YQ Y++WPD VPSS D +L M+ R+ Q P+C+HCSAGCGRTG +C +
Sbjct: 183 ESRSVYQLQYMSWPDRGVPSSPDHMLAMVEEARRLQGSGPEPLCVHCSAGCGRTGVLCTV 242
Query: 245 DYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQ 299
DY LL IP +F++F+++ +MR QR +AVQT+EQY ++ +AQ+F LQ
Sbjct: 243 DYVRQLLLTQMIPPDFSLFDVVLKMRKQRPAAVQTEEQYRFLYHTVAQMFCSTLQ 297
Score = 41.2 bits (95), Expect = 0.004
Identities = 15/21 (71%), Positives = 18/21 (85%)
Query: 760 IGFGNRCGKPKGPRDPPSEWT 780
+GF R G+PKGPRDPP+EWT
Sbjct: 438 LGFNLRIGRPKGPRDPPAEWT 458
>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
precursor [Homo sapiens]
Length = 1441
Score = 199 bits (505), Expect = 1e-50
Identities = 102/243 (41%), Positives = 145/243 (59%), Gaps = 8/243 (3%)
Query: 52 TGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLA 111
T +++EN KNRY +I+ +DHSRV+L + SDYINAN+I G + P+ Y+ATQGP+
Sbjct: 906 TAKEDENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQ 965
Query: 112 NTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQART 171
TV DFWRMIW+ N IVM E+GR KC RYWP +D + K++ + +
Sbjct: 966 ETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYGDIKVTLIETEPLA 1022
Query: 172 DYFIRTLLLEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICI 229
+Y IRT ++ + +E R L FH+ +WPDH VP +L + ++ E PI +
Sbjct: 1023 EYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVV 1082
Query: 230 HCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRA 289
HCSAG GRTG AID +L + ++FN ++E+R QR + VQT+EQY VH A
Sbjct: 1083 HCSAGAGRTGCFIAID---TMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDA 1139
Query: 290 IAQ 292
I +
Sbjct: 1140 ILE 1142
Score = 115 bits (287), Expect = 2e-25
Identities = 81/266 (30%), Positives = 128/266 (48%), Gaps = 21/266 (7%)
Query: 31 DFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYIN 90
+F L ++ + R E + G N KNR D+LP D + + + S+YIN
Sbjct: 1178 EFQTLNIVTPRVRPEDC---SIGLLPRNHDKNRSMDVLPLDRC-LPFLISVDGESSNYIN 1233
Query: 91 ANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWP-- 148
A + P A+V TQ PL NTV DFWR++++YN +VM E + + C +YWP
Sbjct: 1234 AALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVM-LNEMDTA-QFCMQYWPEK 1291
Query: 149 ---LYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDH-DVPS 204
YG + F I DE F + Q+ R + Y+ WP + D P
Sbjct: 1292 TSGCYGPIQVEFVSADI---DEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPP 1348
Query: 205 SFDSILDMISLMRKYQEHED---VPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFN 261
S S+L ++ + K+QE D +HC G GR+G CAI +++ I +
Sbjct: 1349 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNI---ID 1405
Query: 262 VFNLIQEMRTQRHSAVQTKEQYELVH 287
VF++++ +R + + V+T EQY+ V+
Sbjct: 1406 VFHIVKTLRNNKSNMVETLEQYKFVY 1431
>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
precursor [Homo sapiens]
Length = 1460
Score = 199 bits (505), Expect = 1e-50
Identities = 102/243 (41%), Positives = 145/243 (59%), Gaps = 8/243 (3%)
Query: 52 TGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLA 111
T +++EN KNRY +I+ +DHSRV+L + SDYINAN+I G + P+ Y+ATQGP+
Sbjct: 925 TAKEDENRNKNRYGNIISYDHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQ 984
Query: 112 NTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQART 171
TV DFWRMIW+ N IVM E+GR KC RYWP +D + K++ + +
Sbjct: 985 ETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWP---DDTEVYGDIKVTLIETEPLA 1041
Query: 172 DYFIRTLLLEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICI 229
+Y IRT ++ + +E R L FH+ +WPDH VP +L + ++ E PI +
Sbjct: 1042 EYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVV 1101
Query: 230 HCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRA 289
HCSAG GRTG AID +L + ++FN ++E+R QR + VQT+EQY VH A
Sbjct: 1102 HCSAGAGRTGCFIAID---TMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDA 1158
Query: 290 IAQ 292
I +
Sbjct: 1159 ILE 1161
Score = 115 bits (287), Expect = 2e-25
Identities = 81/266 (30%), Positives = 128/266 (48%), Gaps = 21/266 (7%)
Query: 31 DFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYIN 90
+F L ++ + R E + G N KNR D+LP D + + + S+YIN
Sbjct: 1197 EFQTLNIVTPRVRPEDC---SIGLLPRNHDKNRSMDVLPLDRC-LPFLISVDGESSNYIN 1252
Query: 91 ANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWP-- 148
A + P A+V TQ PL NTV DFWR++++YN +VM E + + C +YWP
Sbjct: 1253 AALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVM-LNEMDTA-QFCMQYWPEK 1310
Query: 149 ---LYGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDH-DVPS 204
YG + F I DE F + Q+ R + Y+ WP + D P
Sbjct: 1311 TSGCYGPIQVEFVSADI---DEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPP 1367
Query: 205 SFDSILDMISLMRKYQEHED---VPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFN 261
S S+L ++ + K+QE D +HC G GR+G CAI +++ I +
Sbjct: 1368 SKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNI---ID 1424
Query: 262 VFNLIQEMRTQRHSAVQTKEQYELVH 287
VF++++ +R + + V+T EQY+ V+
Sbjct: 1425 VFHIVKTLRNNKSNMVETLEQYKFVY 1450
>gi|18104993 protein tyrosine phosphatase, non-receptor type 6
isoform 3 [Homo sapiens]
Length = 624
Score = 194 bits (493), Expect = 3e-49
Identities = 126/347 (36%), Positives = 178/347 (51%), Gaps = 28/347 (8%)
Query: 41 KYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPS-QDSDYINANFIKG-VY 98
K + ++ G++ EN KNRYK+ILPFDHSRV L + + SDYINAN+IK +
Sbjct: 253 KQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLL 312
Query: 99 GP----KAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDP 154
GP K Y+A+QG L TV DFW+M W+ N +IVM RE E GR KC YWP G
Sbjct: 313 GPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQR 372
Query: 155 ITFAPFKISCEDEQARTDYFIRTLL---LEFQNESRRLYQFHYVNWPDHDVPSSFDSILD 211
+ P+ ++ E T+Y +RTL L+ + R ++ + Y++WPDH VPS +L
Sbjct: 373 -AYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLS 431
Query: 212 MISLMRKYQEH--EDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEM 269
+ + + QE PI +HCSAG GRTG I ID + + + ++ IQ +
Sbjct: 432 FLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 491
Query: 270 RTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIE-PE 328
R QR VQT+ QY+ ++ AIAQ E + E+ +QK E+ +I P
Sbjct: 492 RAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQK--------GQESEYGNITYPP 543
Query: 329 KQDSPPPKPPRTRSCLVEGDAKEEILQPPE-------PHPVPPILTP 368
+ K RT S +E A P P P PP+L+P
Sbjct: 544 AMKNAHAKASRTSSKSLESSAGTVAASPVRRGGQRGLPVPGPPVLSP 590
>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform b
[Homo sapiens]
Length = 1440
Score = 192 bits (487), Expect = 1e-48
Identities = 97/241 (40%), Positives = 140/241 (58%), Gaps = 8/241 (3%)
Query: 54 EKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANT 113
+K++N KNRY +I+ +DHSRV L SDYINAN+I G P Y+ATQGP+ T
Sbjct: 907 KKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDGYQRPSHYIATQGPVHET 966
Query: 114 VIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDY 173
V DFWRMIW+ IVM E+GR KC +YWP +D + FK++C + + +Y
Sbjct: 967 VYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYGDFKVTCVEMEPLAEY 1023
Query: 174 FIRTLLLEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHC 231
+RT LE + NE R + QFH+ WPDH VP +L I ++ PI +HC
Sbjct: 1024 VVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAGPIVVHC 1083
Query: 232 SAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIA 291
SAG GRTG ID ++ + + +++N ++ +R++R + VQT+EQY +H AI
Sbjct: 1084 SAGAGRTGCYIVIDIMLDMAEREGV---VDIYNCVKALRSRRINMVQTEEQYIFIHDAIL 1140
Query: 292 Q 292
+
Sbjct: 1141 E 1141
Score = 112 bits (281), Expect = 1e-24
Identities = 75/246 (30%), Positives = 117/246 (47%), Gaps = 16/246 (6%)
Query: 58 NVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDF 117
N KNR+ D+LP D + + + S+YINA + P A++ TQ PL NTV DF
Sbjct: 1201 NHDKNRFMDMLPPDRC-LPFLITIDGESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDF 1259
Query: 118 WRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRT 177
WR++++Y IVM E ++ + C +YWP E + + P ++ C D R
Sbjct: 1260 WRLVYDYGCTSIVM-LNEVDLS-QGCPQYWP--EEGMLRYGPIQVECMSCSMDCDVINRI 1315
Query: 178 L----LLEFQNESRRLYQFHYVNWPDH-DVPSSFDSILDMISLMRKYQ---EHEDVPICI 229
L Q + QF Y+ W H +VP S S L +I + K+Q E + I
Sbjct: 1316 FRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTII 1375
Query: 230 HCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRA 289
HC G GR+G CAI ++K + +VF+ ++ +R + + V+ EQY +
Sbjct: 1376 HCLNGGGRSGMFCAIGIVVEMVKRQNV---VDVFHAVKTLRNSKPNMVEAPEQYRFCYDV 1432
Query: 290 IAQLFE 295
+ E
Sbjct: 1433 ALEYLE 1438
>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform 2
precursor [Homo sapiens]
Length = 1452
Score = 190 bits (483), Expect = 4e-48
Identities = 92/246 (37%), Positives = 143/246 (58%), Gaps = 8/246 (3%)
Query: 49 PTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQG 108
P + +K+EN KNRY +I+ +DHSRV+L +SDYIN N+I G + P Y+ATQG
Sbjct: 914 PWDSAKKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQG 973
Query: 109 PLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQ 168
P+ T+ DFWRM+W N I+M E+GR KC +YWP +D + K++ + +
Sbjct: 974 PMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWP---DDTEIYKDIKVTLIETE 1030
Query: 169 ARTDYFIRTLLLEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVP 226
+Y IRT +E + +E R + QFH+ WPDH VP +L + ++ P
Sbjct: 1031 LLAEYVIRTFAVEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGP 1090
Query: 227 ICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELV 286
+ +HCSAG GRTG ID ++ + + +++N ++E+R++R + VQT+EQY +
Sbjct: 1091 LVVHCSAGAGRTGCFIVIDIMLDMAEREGV---VDIYNCVRELRSRRVNMVQTEEQYVFI 1147
Query: 287 HRAIAQ 292
H AI +
Sbjct: 1148 HDAILE 1153
Score = 99.8 bits (247), Expect = 9e-21
Identities = 69/238 (28%), Positives = 113/238 (47%), Gaps = 16/238 (6%)
Query: 58 NVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDF 117
N +KNR DILP D + + + S+YINA + P A++ TQ PL NTV DF
Sbjct: 1213 NHEKNRCMDILPPDRC-LPFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDF 1271
Query: 118 WRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRT 177
WR++ +Y+ +VM + + + C +YWP G P ++ D R
Sbjct: 1272 WRLVLDYHCTSVVM-LNDVDPA-QLCPQYWPENGVH--RHGPIQVEFVSADLEEDIISRI 1327
Query: 178 LLL----EFQNESRRLYQFHYVNWPDH-DVPSSFDSILDMISLMRKYQEH---EDVPICI 229
+ Q+ R + QF ++ WP + D P S S L +I + K+QE + +
Sbjct: 1328 FRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVV 1387
Query: 230 HCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVH 287
HC G GR+G CAI +L+ + +VF+ ++ +R + + V +QY+ +
Sbjct: 1388 HCLNGGGRSGTFCAISIVCEMLRHQR---TVDVFHAVKTLRNNKPNMVDLLDQYKFCY 1442
>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform 1
precursor [Homo sapiens]
Length = 1465
Score = 190 bits (483), Expect = 4e-48
Identities = 92/246 (37%), Positives = 143/246 (58%), Gaps = 8/246 (3%)
Query: 49 PTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQG 108
P + +K+EN KNRY +I+ +DHSRV+L +SDYIN N+I G + P Y+ATQG
Sbjct: 927 PWDSAKKDENRMKNRYGNIIAYDHSRVRLQTIEGDTNSDYINGNYIDGYHRPNHYIATQG 986
Query: 109 PLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQ 168
P+ T+ DFWRM+W N I+M E+GR KC +YWP +D + K++ + +
Sbjct: 987 PMQETIYDFWRMVWHENTASIIMVTNLVEVGRVKCCKYWP---DDTEIYKDIKVTLIETE 1043
Query: 169 ARTDYFIRTLLLEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVP 226
+Y IRT +E + +E R + QFH+ WPDH VP +L + ++ P
Sbjct: 1044 LLAEYVIRTFAVEKRGVHEIREIRQFHFTGWPDHGVPYHATGLLGFVRQVKSKSPPSAGP 1103
Query: 227 ICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELV 286
+ +HCSAG GRTG ID ++ + + +++N ++E+R++R + VQT+EQY +
Sbjct: 1104 LVVHCSAGAGRTGCFIVIDIMLDMAEREGV---VDIYNCVRELRSRRVNMVQTEEQYVFI 1160
Query: 287 HRAIAQ 292
H AI +
Sbjct: 1161 HDAILE 1166
Score = 99.8 bits (247), Expect = 9e-21
Identities = 69/238 (28%), Positives = 113/238 (47%), Gaps = 16/238 (6%)
Query: 58 NVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDF 117
N +KNR DILP D + + + S+YINA + P A++ TQ PL NTV DF
Sbjct: 1226 NHEKNRCMDILPPDRC-LPFLITIDGESSNYINAALMDSYKQPSAFIVTQHPLPNTVKDF 1284
Query: 118 WRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRT 177
WR++ +Y+ +VM + + + C +YWP G P ++ D R
Sbjct: 1285 WRLVLDYHCTSVVM-LNDVDPA-QLCPQYWPENGVH--RHGPIQVEFVSADLEEDIISRI 1340
Query: 178 LLL----EFQNESRRLYQFHYVNWPDH-DVPSSFDSILDMISLMRKYQEH---EDVPICI 229
+ Q+ R + QF ++ WP + D P S S L +I + K+QE + +
Sbjct: 1341 FRIYNAARPQDGYRMVQQFQFLGWPMYRDTPVSKRSFLKLIRQVDKWQEEYNGGEGRTVV 1400
Query: 230 HCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVH 287
HC G GR+G CAI +L+ + +VF+ ++ +R + + V +QY+ +
Sbjct: 1401 HCLNGGGRSGTFCAISIVCEMLRHQR---TVDVFHAVKTLRNNKPNMVDLLDQYKFCY 1455
>gi|18104989 protein tyrosine phosphatase, non-receptor type 6
isoform 1 [Homo sapiens]
Length = 595
Score = 189 bits (479), Expect = 1e-47
Identities = 110/279 (39%), Positives = 156/279 (55%), Gaps = 12/279 (4%)
Query: 41 KYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPS-QDSDYINANFIKG-VY 98
K + ++ G++ EN KNRYK+ILPFDHSRV L + + SDYINAN+IK +
Sbjct: 253 KQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLL 312
Query: 99 GP----KAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDP 154
GP K Y+A+QG L TV DFW+M W+ N +IVM RE E GR KC YWP G
Sbjct: 313 GPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQR 372
Query: 155 ITFAPFKISCEDEQARTDYFIRTLL---LEFQNESRRLYQFHYVNWPDHDVPSSFDSILD 211
+ P+ ++ E T+Y +RTL L+ + R ++ + Y++WPDH VPS +L
Sbjct: 373 -AYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLS 431
Query: 212 MISLMRKYQEH--EDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEM 269
+ + + QE PI +HCSAG GRTG I ID + + + ++ IQ +
Sbjct: 432 FLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 491
Query: 270 RTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQK 308
R QR VQT+ QY+ ++ AIAQ E + E+ +QK
Sbjct: 492 RAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQK 530
>gi|18104991 protein tyrosine phosphatase, non-receptor type 6
isoform 2 [Homo sapiens]
Length = 597
Score = 189 bits (479), Expect = 1e-47
Identities = 110/279 (39%), Positives = 156/279 (55%), Gaps = 12/279 (4%)
Query: 41 KYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPS-QDSDYINANFIKG-VY 98
K + ++ G++ EN KNRYK+ILPFDHSRV L + + SDYINAN+IK +
Sbjct: 255 KQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDSNIPGSDYINANYIKNQLL 314
Query: 99 GP----KAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDP 154
GP K Y+A+QG L TV DFW+M W+ N +IVM RE E GR KC YWP G
Sbjct: 315 GPDENAKTYIASQGCLEATVNDFWQMAWQENSRVIVMTTREVEKGRNKCVPYWPEVGMQR 374
Query: 155 ITFAPFKISCEDEQARTDYFIRTLL---LEFQNESRRLYQFHYVNWPDHDVPSSFDSILD 211
+ P+ ++ E T+Y +RTL L+ + R ++ + Y++WPDH VPS +L
Sbjct: 375 -AYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDLIREIWHYQYLSWPDHGVPSEPGGVLS 433
Query: 212 MISLMRKYQEH--EDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEM 269
+ + + QE PI +HCSAG GRTG I ID + + + ++ IQ +
Sbjct: 434 FLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMENISTKGLDCDIDIQKTIQMV 493
Query: 270 RTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQK 308
R QR VQT+ QY+ ++ AIAQ E + E+ +QK
Sbjct: 494 RAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVLQSQK 532
>gi|148728162 protein tyrosine phosphatase, receptor type, J isoform 1
precursor [Homo sapiens]
Length = 1337
Score = 186 bits (473), Expect = 5e-47
Identities = 99/253 (39%), Positives = 147/253 (58%), Gaps = 10/253 (3%)
Query: 49 PTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQG 108
P E EN KNRY ++LP+D SRVKL+++T S D DYINAN++ G + K ++ATQG
Sbjct: 1056 PKYAAELAENRGKNRYNNVLPYDISRVKLSVQTHSTD-DYINANYMPGYHSKKDFIATQG 1114
Query: 109 PLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQ 168
PL NT+ DFWRM+WE NV I+M + E GR KCE YWP + + ++ E
Sbjct: 1115 PLPNTLKDFWRMVWEKNVYAIIMLTKCVEQGRTKCEEYWP--SKQAQDYGDITVAMTSEI 1172
Query: 169 ARTDYFIRTLLLE--FQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKY--QEHED 224
++ IR ++ +ES L QFH+ +WPDH VP + D +++ L+R Y Q +
Sbjct: 1173 VLPEWTIRDFTVKNIQTSESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQSPPE 1232
Query: 225 VPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYE 284
PI +HCSAG GRTG AID L+ + +V+ ++ ++R R VQT++QY
Sbjct: 1233 SPILVHCSAGVGRTGTFIAID---RLIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYV 1289
Query: 285 LVHRAIAQLFEKQ 297
+++ + + Q
Sbjct: 1290 FLNQCVLDIVRSQ 1302
>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
[Homo sapiens]
Length = 1446
Score = 185 bits (470), Expect = 1e-46
Identities = 97/247 (39%), Positives = 140/247 (56%), Gaps = 14/247 (5%)
Query: 54 EKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIK------GVYGPKAYVATQ 107
+K++N KNRY +I+ +DHSRV L SDYINAN+I G P Y+ATQ
Sbjct: 907 KKDQNRAKNRYGNIIAYDHSRVILQPVEDDPSSDYINANYIDIWLYRDGYQRPSHYIATQ 966
Query: 108 GPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDE 167
GP+ TV DFWRMIW+ IVM E+GR KC +YWP +D + FK++C +
Sbjct: 967 GPVHETVYDFWRMIWQEQSACIVMVTNLVEVGRVKCYKYWP---DDTEVYGDFKVTCVEM 1023
Query: 168 QARTDYFIRTLLLEFQ--NESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDV 225
+ +Y +RT LE + NE R + QFH+ WPDH VP +L I ++
Sbjct: 1024 EPLAEYVVRTFTLERRGYNEIREVKQFHFTGWPDHGVPYHATGLLSFIRRVKLSNPPSAG 1083
Query: 226 PICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYEL 285
PI +HCSAG GRTG ID ++ + + +++N ++ +R++R + VQT+EQY
Sbjct: 1084 PIVVHCSAGAGRTGCYIVIDIMLDMAEREGV---VDIYNCVKALRSRRINMVQTEEQYIF 1140
Query: 286 VHRAIAQ 292
+H AI +
Sbjct: 1141 IHDAILE 1147
Score = 112 bits (281), Expect = 1e-24
Identities = 75/246 (30%), Positives = 117/246 (47%), Gaps = 16/246 (6%)
Query: 58 NVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDF 117
N KNR+ D+LP D + + + S+YINA + P A++ TQ PL NTV DF
Sbjct: 1207 NHDKNRFMDMLPPDRC-LPFLITIDGESSNYINAALMDSYRQPAAFIVTQYPLPNTVKDF 1265
Query: 118 WRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRT 177
WR++++Y IVM E ++ + C +YWP E + + P ++ C D R
Sbjct: 1266 WRLVYDYGCTSIVM-LNEVDLS-QGCPQYWP--EEGMLRYGPIQVECMSCSMDCDVINRI 1321
Query: 178 L----LLEFQNESRRLYQFHYVNWPDH-DVPSSFDSILDMISLMRKYQ---EHEDVPICI 229
L Q + QF Y+ W H +VP S S L +I + K+Q E + I
Sbjct: 1322 FRICNLTRPQEGYLMVQQFQYLGWASHREVPGSKRSFLKLILQVEKWQEECEEGEGRTII 1381
Query: 230 HCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRA 289
HC G GR+G CAI ++K + +VF+ ++ +R + + V+ EQY +
Sbjct: 1382 HCLNGGGRSGMFCAIGIVVEMVKRQNV---VDVFHAVKTLRNSKPNMVEAPEQYRFCYDV 1438
Query: 290 IAQLFE 295
+ E
Sbjct: 1439 ALEYLE 1444
>gi|241896926 protein tyrosine phosphatase, receptor type, H isoform
2 precursor [Homo sapiens]
Length = 937
Score = 184 bits (466), Expect = 4e-46
Identities = 99/247 (40%), Positives = 143/247 (57%), Gaps = 8/247 (3%)
Query: 57 ENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVID 116
EN KNRY+++LP+D SRV L SDYINA+F+ G++ P+ ++ATQGPL TV D
Sbjct: 665 ENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGD 724
Query: 117 FWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIR 176
FWR++WE +VM E GR KCE YWPL P T +++ E+ ++ +R
Sbjct: 725 FWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPL-DSQPCTHGHLRVTLVGEEVMENWTVR 783
Query: 177 TLLLEFQNESRRL--YQFHYVNWPDHDVPSSFDSILDMISLMRKY--QEHEDVPICIHCS 232
LLL E + L QFHY WPDH VPSS D++L ++R++ Q E P +HCS
Sbjct: 784 ELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCS 843
Query: 233 AGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 292
AG GRTG + A+D L++ + F+ +++MR R VQT+ QY +H+ I +
Sbjct: 844 AGVGRTGTLIALDVLLRQLQSEGL---LGPFSFVRKMRESRPLMVQTEAQYVFLHQCILR 900
Query: 293 LFEKQLQ 299
++ Q
Sbjct: 901 FLQQSAQ 907
>gi|241896924 protein tyrosine phosphatase, receptor type, H isoform 1
precursor [Homo sapiens]
Length = 1115
Score = 184 bits (466), Expect = 4e-46
Identities = 99/247 (40%), Positives = 143/247 (57%), Gaps = 8/247 (3%)
Query: 57 ENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVID 116
EN KNRY+++LP+D SRV L SDYINA+F+ G++ P+ ++ATQGPL TV D
Sbjct: 843 ENNAKNRYRNVLPYDWSRVPLKPIHEEPGSDYINASFMPGLWSPQEFIATQGPLPQTVGD 902
Query: 117 FWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIR 176
FWR++WE +VM E GR KCE YWPL P T +++ E+ ++ +R
Sbjct: 903 FWRLVWEQQSHTLVMLTNCMEAGRVKCEHYWPL-DSQPCTHGHLRVTLVGEEVMENWTVR 961
Query: 177 TLLLEFQNESRRL--YQFHYVNWPDHDVPSSFDSILDMISLMRKY--QEHEDVPICIHCS 232
LLL E + L QFHY WPDH VPSS D++L ++R++ Q E P +HCS
Sbjct: 962 ELLLLQVEEQKTLSVRQFHYQAWPDHGVPSSPDTLLAFWRMLRQWLDQTMEGGPPIVHCS 1021
Query: 233 AGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ 292
AG GRTG + A+D L++ + F+ +++MR R VQT+ QY +H+ I +
Sbjct: 1022 AGVGRTGTLIALDVLLRQLQSEGL---LGPFSFVRKMRESRPLMVQTEAQYVFLHQCILR 1078
Query: 293 LFEKQLQ 299
++ Q
Sbjct: 1079 FLQQSAQ 1085
>gi|13677222 receptor-type protein tyrosine phosphatase O isoform c
precursor [Homo sapiens]
Length = 405
Score = 183 bits (464), Expect = 6e-46
Identities = 94/243 (38%), Positives = 143/243 (58%), Gaps = 6/243 (2%)
Query: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
KNRY +ILP+D SRV+L + +DYINAN+I G P+ Y+ATQGPL T DFW+M
Sbjct: 154 KNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKM 213
Query: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL 180
+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R +
Sbjct: 214 VLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFRI 272
Query: 181 EFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRT 238
+ +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GRT
Sbjct: 273 NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRT 332
Query: 239 GAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQL 298
G A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 333 GTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK 389
Query: 299 QLY 301
Q +
Sbjct: 390 QQF 392
>gi|13677220 receptor-type protein tyrosine phosphatase O isoform d
precursor [Homo sapiens]
Length = 377
Score = 183 bits (464), Expect = 6e-46
Identities = 94/243 (38%), Positives = 143/243 (58%), Gaps = 6/243 (2%)
Query: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
KNRY +ILP+D SRV+L + +DYINAN+I G P+ Y+ATQGPL T DFW+M
Sbjct: 126 KNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKM 185
Query: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL 180
+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R +
Sbjct: 186 VLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFRI 244
Query: 181 EFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRT 238
+ +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GRT
Sbjct: 245 NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRT 304
Query: 239 GAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQL 298
G A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 305 GTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK 361
Query: 299 QLY 301
Q +
Sbjct: 362 QQF 364
>gi|13677218 receptor-type protein tyrosine phosphatase O isoform c
precursor [Homo sapiens]
Length = 405
Score = 183 bits (464), Expect = 6e-46
Identities = 94/243 (38%), Positives = 143/243 (58%), Gaps = 6/243 (2%)
Query: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
KNRY +ILP+D SRV+L + +DYINAN+I G P+ Y+ATQGPL T DFW+M
Sbjct: 154 KNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKM 213
Query: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL 180
+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R +
Sbjct: 214 VLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFRI 272
Query: 181 EFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRT 238
+ +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GRT
Sbjct: 273 NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRT 332
Query: 239 GAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQL 298
G A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 333 GTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK 389
Query: 299 QLY 301
Q +
Sbjct: 390 QQF 392
>gi|13677216 receptor-type protein tyrosine phosphatase O isoform d
precursor [Homo sapiens]
Length = 377
Score = 183 bits (464), Expect = 6e-46
Identities = 94/243 (38%), Positives = 143/243 (58%), Gaps = 6/243 (2%)
Query: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
KNRY +ILP+D SRV+L + +DYINAN+I G P+ Y+ATQGPL T DFW+M
Sbjct: 126 KNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKM 185
Query: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL 180
+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R +
Sbjct: 186 VLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFRI 244
Query: 181 EFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRT 238
+ +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GRT
Sbjct: 245 NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRT 304
Query: 239 GAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQL 298
G A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 305 GTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK 361
Query: 299 QLY 301
Q +
Sbjct: 362 QQF 364
>gi|13677214 receptor-type protein tyrosine phosphatase O isoform a
precursor [Homo sapiens]
Length = 1216
Score = 183 bits (464), Expect = 6e-46
Identities = 94/243 (38%), Positives = 143/243 (58%), Gaps = 6/243 (2%)
Query: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
KNRY +ILP+D SRV+L + +DYINAN+I G P+ Y+ATQGPL T DFW+M
Sbjct: 965 KNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKM 1024
Query: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL 180
+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R +
Sbjct: 1025 VLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFRI 1083
Query: 181 EFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRT 238
+ +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GRT
Sbjct: 1084 NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRT 1143
Query: 239 GAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQL 298
G A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 1144 GTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK 1200
Query: 299 QLY 301
Q +
Sbjct: 1201 QQF 1203
>gi|4506323 receptor-type protein tyrosine phosphatase O isoform b
precursor [Homo sapiens]
Length = 1188
Score = 183 bits (464), Expect = 6e-46
Identities = 94/243 (38%), Positives = 143/243 (58%), Gaps = 6/243 (2%)
Query: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
KNRY +ILP+D SRV+L + +DYINAN+I G P+ Y+ATQGPL T DFW+M
Sbjct: 937 KNRYTNILPYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKM 996
Query: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL 180
+ + IIVM + E R KC+ YWP + E+PI + + E+ + D+ R +
Sbjct: 997 VLQQKSQIIVMLTQCNEKRRVKCDHYWP-FTEEPIAYGDITVEMISEEEQDDWACRHFRI 1055
Query: 181 EFQNESRRLYQFHYVNWPDHDVP--SSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRT 238
+ +E + + F+Y WPDH VP ++ +SIL + ++R+ P+ IHCSAG GRT
Sbjct: 1056 NYADEMQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRT 1115
Query: 239 GAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQL 298
G A+D LL+ + E ++ L+ EMR+ R S VQT+EQY +H+ + ++ K+
Sbjct: 1116 GTFIALD---RLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKK 1172
Query: 299 QLY 301
Q +
Sbjct: 1173 QQF 1175
>gi|33356177 protein tyrosine phosphatase, non-receptor type 11
[Homo sapiens]
Length = 593
Score = 180 bits (457), Expect = 4e-45
Identities = 116/331 (35%), Positives = 171/331 (51%), Gaps = 25/331 (7%)
Query: 25 EDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQ 84
+ F +F L++ K +Y G+++EN KNRYK+ILPFDH+RV L P++
Sbjct: 244 KQGFWEEFETLQQQECKL----LYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNE 299
Query: 85 D-SDYINANFIKGVYGPK--------AYVATQGPLANTVIDFWRMIWEYNVVIIVMACRE 135
SDYINAN I + K +Y+ATQG L NTV DFWRM+++ N +IVM +E
Sbjct: 300 PVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKE 359
Query: 136 FEMGRKKCERYWPLYGEDPI-TFAPFKISCEDEQARTDYFIRTLLLE---FQNESRRLYQ 191
E G+ KC +YWP E + + ++ E A DY +R L L N R ++Q
Sbjct: 360 VERGKSKCVKYWP--DEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQ 417
Query: 192 FHYVNWPDHDVPSSFDSILDMISLMRKYQEH--EDVPICIHCSAGCGRTGAICAIDYTWN 249
+H+ WPDH VPS +LD + + QE + P+ +HCSAG GRTG ID +
Sbjct: 418 YHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILID 477
Query: 250 LLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKI 309
+++ + + +V IQ +R+QR VQT+ QY ++ A+ E + I QK
Sbjct: 478 IIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQR--RIEEEQKS 535
Query: 310 ADGVNEINTENMVSSIEPEKQDSPPPKPPRT 340
+E N+ S+ + P PP T
Sbjct: 536 KRKGHEYT--NIKYSLADQTSGDQSPLPPCT 564
>gi|18450371 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 180 bits (457), Expect = 4e-45
Identities = 93/260 (35%), Positives = 153/260 (58%), Gaps = 11/260 (4%)
Query: 39 STKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVY 98
S K + +K+ TG N+KKNR I+P++ +RV + +K +++DY+NA+FI G
Sbjct: 533 SIKIQNDKM---RTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 589
Query: 99 GPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFA 158
+Y+A+QGPL +T+ DFWRMIWE+ IVM E G++KC +YWP + +++
Sbjct: 590 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYG 647
Query: 159 PFKISCEDEQARTDYFIRTLLL--EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLM 216
+ + E+ Y +R LL+ +N+SR++ QFH+ WP+ +PS ++ +I+ +
Sbjct: 648 DITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAV 707
Query: 217 RKYQEHE-DVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHS 275
+K Q+ + PI +HCSAG GRTG CA+ +KA I +VF ++ +R QR
Sbjct: 708 QKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPH 764
Query: 276 AVQTKEQYELVHRAIAQLFE 295
VQT EQYE ++ + + +
Sbjct: 765 MVQTLEQYEFCYKVVQEYID 784
Score = 167 bits (422), Expect = 5e-41
Identities = 92/244 (37%), Positives = 129/244 (52%), Gaps = 11/244 (4%)
Query: 55 KEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTV 114
KEEN +KNRY +ILP+DHSRV LT DSDYINA+FI G ++A QGP TV
Sbjct: 253 KEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETV 312
Query: 115 IDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYF 174
DFWRMIWE N IVM E KC +YWP G T+ ++S ED DY
Sbjct: 313 NDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQG--CWTYGNIRVSVEDVTVLVDYT 370
Query: 175 IRTLLLE------FQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPIC 228
+R ++ + R + QFH+ +WPD VP + +L + ++ I
Sbjct: 371 VRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIV 430
Query: 229 IHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHR 288
+HCSAG GRTG ID +++ + + +V+ + +R QR VQT QY +++
Sbjct: 431 VHCSAGVGRTGTFVVIDAMLDMMHTER---KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQ 487
Query: 289 AIAQ 292
A+ +
Sbjct: 488 ALLE 491
>gi|4506303 protein tyrosine phosphatase, receptor type, A isoform 1
precursor [Homo sapiens]
Length = 802
Score = 180 bits (457), Expect = 4e-45
Identities = 93/260 (35%), Positives = 153/260 (58%), Gaps = 11/260 (4%)
Query: 39 STKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVY 98
S K + +K+ TG N+KKNR I+P++ +RV + +K +++DY+NA+FI G
Sbjct: 542 SIKIQNDKM---RTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 598
Query: 99 GPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFA 158
+Y+A+QGPL +T+ DFWRMIWE+ IVM E G++KC +YWP + +++
Sbjct: 599 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYG 656
Query: 159 PFKISCEDEQARTDYFIRTLLL--EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLM 216
+ + E+ Y +R LL+ +N+SR++ QFH+ WP+ +PS ++ +I+ +
Sbjct: 657 DITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAV 716
Query: 217 RKYQEHE-DVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHS 275
+K Q+ + PI +HCSAG GRTG CA+ +KA I +VF ++ +R QR
Sbjct: 717 QKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPH 773
Query: 276 AVQTKEQYELVHRAIAQLFE 295
VQT EQYE ++ + + +
Sbjct: 774 MVQTLEQYEFCYKVVQEYID 793
Score = 167 bits (422), Expect = 5e-41
Identities = 92/244 (37%), Positives = 129/244 (52%), Gaps = 11/244 (4%)
Query: 55 KEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTV 114
KEEN +KNRY +ILP+DHSRV LT DSDYINA+FI G ++A QGP TV
Sbjct: 262 KEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETV 321
Query: 115 IDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYF 174
DFWRMIWE N IVM E KC +YWP G T+ ++S ED DY
Sbjct: 322 NDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQG--CWTYGNIRVSVEDVTVLVDYT 379
Query: 175 IRTLLLE------FQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPIC 228
+R ++ + R + QFH+ +WPD VP + +L + ++ I
Sbjct: 380 VRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIV 439
Query: 229 IHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHR 288
+HCSAG GRTG ID +++ + + +V+ + +R QR VQT QY +++
Sbjct: 440 VHCSAGVGRTGTFVVIDAMLDMMHTER---KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQ 496
Query: 289 AIAQ 292
A+ +
Sbjct: 497 ALLE 500
>gi|18450369 protein tyrosine phosphatase, receptor type, A isoform
2 precursor [Homo sapiens]
Length = 793
Score = 180 bits (457), Expect = 4e-45
Identities = 93/260 (35%), Positives = 153/260 (58%), Gaps = 11/260 (4%)
Query: 39 STKYRTEKIYPTATGEKEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVY 98
S K + +K+ TG N+KKNR I+P++ +RV + +K +++DY+NA+FI G
Sbjct: 533 SIKIQNDKM---RTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYR 589
Query: 99 GPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFA 158
+Y+A+QGPL +T+ DFWRMIWE+ IVM E G++KC +YWP + +++
Sbjct: 590 QKDSYIASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWP--SDGLVSYG 647
Query: 159 PFKISCEDEQARTDYFIRTLLL--EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLM 216
+ + E+ Y +R LL+ +N+SR++ QFH+ WP+ +PS ++ +I+ +
Sbjct: 648 DITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFHFHGWPEVGIPSDGKGMISIIAAV 707
Query: 217 RKYQEHE-DVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHS 275
+K Q+ + PI +HCSAG GRTG CA+ +KA I +VF ++ +R QR
Sbjct: 708 QKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGI---LDVFQTVKSLRLQRPH 764
Query: 276 AVQTKEQYELVHRAIAQLFE 295
VQT EQYE ++ + + +
Sbjct: 765 MVQTLEQYEFCYKVVQEYID 784
Score = 167 bits (422), Expect = 5e-41
Identities = 92/244 (37%), Positives = 129/244 (52%), Gaps = 11/244 (4%)
Query: 55 KEENVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTV 114
KEEN +KNRY +ILP+DHSRV LT DSDYINA+FI G ++A QGP TV
Sbjct: 253 KEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETV 312
Query: 115 IDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYF 174
DFWRMIWE N IVM E KC +YWP G T+ ++S ED DY
Sbjct: 313 NDFWRMIWEQNTATIVMVTNLKERKECKCAQYWPDQG--CWTYGNIRVSVEDVTVLVDYT 370
Query: 175 IRTLLLE------FQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPIC 228
+R ++ + R + QFH+ +WPD VP + +L + ++ I
Sbjct: 371 VRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKFLKKVKACNPQYAGAIV 430
Query: 229 IHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHR 288
+HCSAG GRTG ID +++ + + +V+ + +R QR VQT QY +++
Sbjct: 431 VHCSAGVGRTGTFVVIDAMLDMMHTER---KVDVYGFVSRIRAQRCQMVQTDMQYVFIYQ 487
Query: 289 AIAQ 292
A+ +
Sbjct: 488 ALLE 491
>gi|4506301 protein tyrosine phosphatase, non-receptor type 9 [Homo
sapiens]
Length = 593
Score = 179 bits (455), Expect = 7e-45
Identities = 98/256 (38%), Positives = 145/256 (56%), Gaps = 20/256 (7%)
Query: 58 NVKKNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDF 117
N++KNRY D+ D +RVKLT ++ +DYINA+F+ G AY+ TQGPL NT DF
Sbjct: 327 NLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDF 386
Query: 118 WRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRT 177
W M+WE V++IVM R E GR+KC +YWPL + I F ++ + Y T
Sbjct: 387 WLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTT 446
Query: 178 LLLE--FQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQ-------------EH 222
L + + + R++ F +++WPD+ VPSS S++D + ++R Q +
Sbjct: 447 LEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQC 506
Query: 223 EDVPICIHCSAGCGRTGAICAIDYTW-NLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKE 281
+ PI +HCSAG GRTG C++D L + G + NVF + MRTQR ++QT E
Sbjct: 507 PEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTL----NVFQTVSRMRTQRAFSIQTPE 562
Query: 282 QYELVHRAIAQLFEKQ 297
QY ++AI + EK+
Sbjct: 563 QYYFCYKAILEFAEKE 578
>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
precursor [Homo sapiens]
Length = 2315
Score = 177 bits (449), Expect = 3e-44
Identities = 99/300 (33%), Positives = 158/300 (52%), Gaps = 21/300 (7%)
Query: 21 DHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKE---ENVKKNRYKDILPFDHSRVKL 77
D + F +F L+ + ++ + T + +N KNRY +I+ +DHSRVKL
Sbjct: 1710 DLHASSGFTEEFETLKEFYQEVQSCTVDLGITADSSNHPDNKHKNRYINIVAYDHSRVKL 1769
Query: 78 T--LKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACRE 135
+ + +DYINAN++ G PKAY+A QGPL +T DFWRMIWE+NV +IVM
Sbjct: 1770 AQLAEKDGKLTDYINANYVDGYNRPKAYIAAQGPLKSTAEDFWRMIWEHNVEVIVMITNL 1829
Query: 136 FEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL----------EFQNE 185
E GR+KC++YWP G + + F ++ + Q Y +R L + +
Sbjct: 1830 VEKGRRKCDQYWPADGSE--EYGNFLVTQKSVQVLAYYTVRNFTLRNTKIKKGSQKGRPS 1887
Query: 186 SRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAID 245
R + Q+HY WPD VP +L + + H P+ +HCSAG GRTG +D
Sbjct: 1888 GRVVTQYHYTQWPDMGVPEYSLPVLTFVRKAAYAKRHAVGPVVVHCSAGVGRTGTYIVLD 1947
Query: 246 YTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQ-LFEKQLQLYEIH 304
++L+ + N+F ++ +R+QR+ VQT+EQY +H + + + K+ ++ + H
Sbjct: 1948 ---SMLQQIQHEGTVNIFGFLKHIRSQRNYLVQTEEQYVFIHDTLVEAILSKETEVLDSH 2004
Score = 108 bits (270), Expect = 2e-23
Identities = 82/300 (27%), Positives = 143/300 (47%), Gaps = 21/300 (7%)
Query: 2 EQVEILRKFIQR-VQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK 60
++ E+L I V A+ P G+ + F L + + + + Y A K+ N +
Sbjct: 1996 KETEVLDSHIHAYVNALLIPGPAGKTKLEKQFQLLSQSNIQ---QSDYSAAL--KQCNRE 2050
Query: 61 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM 120
KNR I+P + SRV ++ + +DYINA++I G Y ++ TQ PL +T+ DFWRM
Sbjct: 2051 KNRTSSIIPVERSRVGIS-SLSGEGTDYINASYIMGYYQSNEFIITQHPLLHTIKDFWRM 2109
Query: 121 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQAR-----TDYFI 175
IW++N ++VM M + YWP ++PI FK++ E+ + I
Sbjct: 2110 IWDHNAQLVVMIPDGQNMAEDEFV-YWP-NKDEPINCESFKVTLMAEEHKCLSNEEKLII 2167
Query: 176 RTLLLEFQNESRRLYQFHY--VNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSA 233
+ +LE + L H+ WP+ D P S ++IS++++ + D P+ +H
Sbjct: 2168 QDFILEATQDDYVLEVRHFQCPKWPNPDSPIS--KTFELISVIKEEAANRDGPMIVHDEH 2225
Query: 234 GCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQL 293
G G CA+ + L+ + + V +I MR + + EQY+ +++ I L
Sbjct: 2226 GGVTAGTFCALTTLMHQLEKENSVDVYQVAKMINLMRPGVFADI---EQYQFLYKVILSL 2282
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,102,602
Number of Sequences: 37866
Number of extensions: 1875209
Number of successful extensions: 9575
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 134
Number of HSP's successfully gapped in prelim test: 302
Number of HSP's that attempted gapping in prelim test: 7768
Number of HSP's gapped (non-prelim): 1541
length of query: 780
length of database: 18,247,518
effective HSP length: 110
effective length of query: 670
effective length of database: 14,082,258
effective search space: 9435112860
effective search space used: 9435112860
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.