Guide to the Human Genome
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Search of human proteins with 194306644

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194306644 BCSC-1 isoform 1 [Homo sapiens]
         (786 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194306644 BCSC-1 isoform 1 [Homo sapiens]                         1566   0.0  
gi|38195080 BCSC-1 isoform 1 [Homo sapiens]                          1566   0.0  
gi|38195082 BCSC-1 isoform 2 [Homo sapiens]                           829   0.0  
gi|210147462 von Willebrand factor A domain containing 5B1 [Homo...   225   1e-58
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo...   161   2e-39
gi|222352129 von Willebrand factor A domain containing 5B2 [Homo...   142   2e-33
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]        67   5e-11
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]         67   5e-11
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]    56   1e-07
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [...    49   2e-05
gi|218505703 von Willebrand factor A domain containing 3A [Homo ...    42   0.002
gi|27262622 neuron navigator 1 [Homo sapiens]                          35   0.35 
gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]         33   0.78 
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ...    32   2.3  
gi|31317228 early growth response 3 [Homo sapiens]                     31   3.9  
gi|46249395 Ras-related GTP binding B short isoform [Homo sapiens]     31   5.1  
gi|42741659 ATP-binding cassette, subfamily B, member 1 [Homo sa...    30   8.7  
gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3 c...    30   8.7  
gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3 c...    30   8.7  
gi|13540533 N-acetylneuraminate pyruvate lyase [Homo sapiens]          30   8.7  
gi|148596992 heart alpha-kinase [Homo sapiens]                         30   8.7  

>gi|194306644 BCSC-1 isoform 1 [Homo sapiens]
          Length = 786

 Score = 1566 bits (4055), Expect = 0.0
 Identities = 786/786 (100%), Positives = 786/786 (100%)

Query: 1   MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSA 60
           MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSA
Sbjct: 1   MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSA 60

Query: 61  VYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPG 120
           VYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPG
Sbjct: 61  VYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPG 120

Query: 121 SKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTL 180
           SKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTL
Sbjct: 121 SKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTL 180

Query: 181 SMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTP 240
           SMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTP
Sbjct: 181 SMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTP 240

Query: 241 SVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQD 300
           SVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQD
Sbjct: 241 SVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQD 300

Query: 301 TSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLM 360
           TSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLM
Sbjct: 301 TSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLM 360

Query: 361 QADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFG 420
           QADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFG
Sbjct: 361 QADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFG 420

Query: 421 IGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLS 480
           IGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLS
Sbjct: 421 IGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLS 480

Query: 481 AKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPD 540
           AKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPD
Sbjct: 481 AKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPD 540

Query: 541 VNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQ 600
           VNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQ
Sbjct: 541 VNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQ 600

Query: 601 GPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDY 660
           GPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDY
Sbjct: 601 GPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDY 660

Query: 661 SLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELV 720
           SLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELV
Sbjct: 661 SLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELV 720

Query: 721 DSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVD 780
           DSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVD
Sbjct: 721 DSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVD 780

Query: 781 PAIFAF 786
           PAIFAF
Sbjct: 781 PAIFAF 786


>gi|38195080 BCSC-1 isoform 1 [Homo sapiens]
          Length = 786

 Score = 1566 bits (4055), Expect = 0.0
 Identities = 786/786 (100%), Positives = 786/786 (100%)

Query: 1   MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSA 60
           MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSA
Sbjct: 1   MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSA 60

Query: 61  VYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPG 120
           VYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPG
Sbjct: 61  VYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPG 120

Query: 121 SKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTL 180
           SKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTL
Sbjct: 121 SKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTL 180

Query: 181 SMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTP 240
           SMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTP
Sbjct: 181 SMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTP 240

Query: 241 SVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQD 300
           SVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQD
Sbjct: 241 SVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQD 300

Query: 301 TSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLM 360
           TSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLM
Sbjct: 301 TSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLM 360

Query: 361 QADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFG 420
           QADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFG
Sbjct: 361 QADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFG 420

Query: 421 IGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLS 480
           IGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLS
Sbjct: 421 IGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLS 480

Query: 481 AKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPD 540
           AKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPD
Sbjct: 481 AKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPD 540

Query: 541 VNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQ 600
           VNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQ
Sbjct: 541 VNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQ 600

Query: 601 GPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDY 660
           GPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDY
Sbjct: 601 GPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDY 660

Query: 661 SLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELV 720
           SLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELV
Sbjct: 661 SLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELV 720

Query: 721 DSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVD 780
           DSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVD
Sbjct: 721 DSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVD 780

Query: 781 PAIFAF 786
           PAIFAF
Sbjct: 781 PAIFAF 786


>gi|38195082 BCSC-1 isoform 2 [Homo sapiens]
          Length = 415

 Score =  829 bits (2141), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSA 60
           MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSA
Sbjct: 1   MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSA 60

Query: 61  VYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPG 120
           VYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPG
Sbjct: 61  VYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPG 120

Query: 121 SKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTL 180
           SKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTL
Sbjct: 121 SKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTL 180

Query: 181 SMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTP 240
           SMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTP
Sbjct: 181 SMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTP 240

Query: 241 SVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQD 300
           SVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQD
Sbjct: 241 SVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQD 300

Query: 301 TSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLM 360
           TSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLM
Sbjct: 301 TSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLM 360

Query: 361 QADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHR 415
           QADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHR
Sbjct: 361 QADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHR 415


>gi|210147462 von Willebrand factor A domain containing 5B1 [Homo
           sapiens]
          Length = 1215

 Score =  225 bits (574), Expect = 1e-58
 Identities = 168/570 (29%), Positives = 269/570 (47%), Gaps = 95/570 (16%)

Query: 15  VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74
           +PL +  V+  +  +  G++A+L Y N E  P +  FV+P+DE + V  FEA++  + + 
Sbjct: 13  LPLTASDVTSCVSGYALGLTASLTYGNLEAQPFQGLFVYPLDECTTVIGFEAVIADRVVT 72

Query: 75  AELQDKMKARTNYEKAISQGHQA----FLLEGDSSS----------------RDVFSCNV 114
            +++DK K  + +  A            L +G S +                R +F  N+
Sbjct: 73  VQIKDKAKLESGHFDASHVRSPTVTGNILQDGVSIAPHSCTPGKVTLDEDLERILFVANL 132

Query: 115 GNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRY-QF----SGSSKDSCLNVKTP 169
           G + P     + +    ELP    GA+R +LPAV  P   QF    +G+S          
Sbjct: 133 GTIAPMENVTIFISTSSELPTLPSGAVRVLLPAVCAPTVPQFCTKSTGTSNQQAQGKDRH 192

Query: 170 I----VPVEDLPYTLSMVATIDSQHGIE-------KVQSNCPL----SPTEYLGEDKT-- 212
                 P       L+ +   +  + +E       +++  C L    SPT  +  D    
Sbjct: 193 CFGAWAPGSWNKLCLATLLNTEVSNPMEYEFNFQLEIRGPCLLAGVESPTHEIRADAAPS 252

Query: 213 -----SAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPG----HLMGDPS-- 261
                S  ++LA  H FDR VE+LI+ +E H P V++E G  +M  G    HL G     
Sbjct: 253 ARSAKSIIITLANKHTFDRPVEILIHPSEPHMPHVLIEKG--DMTLGEFDQHLKGRTDFI 310

Query: 262 -----------------------------AMVSFYPNIPEDQPS--NTCGEFIFLMDRSG 290
                                         M++F P++   QP      GEFIFL+DRS 
Sbjct: 311 KGMKKKSRAERKTEIIRKRLHKDIPHHSVIMLNFCPDLQSVQPCLRKAHGEFIFLIDRSS 370

Query: 291 SMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTM 350
           SM         S + +   K+ +++ LKSL   C FNI GFGS++++ FP S  Y++ ++
Sbjct: 371 SM---------SGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSL 421

Query: 351 EEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRIN 410
             A   ++ M+AD+GGT IL+PL+ + R P   GHP  LFV TDG V +T  V++ VR +
Sbjct: 422 AMACDDIQRMKADMGGTNILSPLKWVIRQPVHRGHPRLLFVITDGAVNNTGKVLELVRNH 481

Query: 411 RQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVS 470
               RC+SFGIG      L+KG+A  S G++E +   +R+Q K +++LK+++ PV+ DV+
Sbjct: 482 AFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSLKKAMAPVLSDVT 541

Query: 471 LSWHLPPGLSAKMLSPEQTVIFRGQRLISY 500
           + W  P      +     + +F G+RL+ Y
Sbjct: 542 VEWIFPETTEVLVSPVSASSLFPGERLVGY 571



 Score = 37.4 bits (85), Expect = 0.054
 Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 2/47 (4%)

Query: 712  MAAQPAELVDSSG--WATILAVIWLHSNGKDLKCEWELLERKAVAWM 756
            +  +P  +V+ +G  WAT++ + WL  +      EWEL+  KA +W+
Sbjct: 1125 LGLEPRAVVEHTGKLWATVVGLAWLEHSSASYFTEWELVAAKANSWL 1171


>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
            sapiens]
          Length = 1724

 Score =  161 bits (408), Expect = 2e-39
 Identities = 156/596 (26%), Positives = 270/596 (45%), Gaps = 53/596 (8%)

Query: 15   VPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIV 74
            VPL+ + +   I + VA V     Y N+  VP+EA ++FP+D+ +AV  FEA ++GK IV
Sbjct: 621  VPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIV 680

Query: 75   AELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELP 134
             E+++K +A+  Y +A++QGH A+L+  D+   DVF+ +VGNL P +K  + + Y+ EL 
Sbjct: 681  GEIKEKEEAQQEYLEAVTQGHGAYLMSQDAP--DVFTVSVGNLPPKAKVLIKITYITELS 738

Query: 135  LEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEK 194
            +     + F +PA + P  Q    +++    V+   +       + S+  +I+  + IE 
Sbjct: 739  ILGTVGV-FFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQSFSLTMSIEMPYVIEF 797

Query: 195  VQSNCPLSPTEYLGEDKT--SAQVSLAAGHKFDRD-VELLIYYNEVHTPSVVLEMGMPNM 251
            +      S T  L + +T   A +S   G   D     L I  +  + P + +E   P  
Sbjct: 798  I-----FSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEK-HPEK 851

Query: 252  KPGHLMGDPSAMVSFYPNIPEDQPSNTC-GEFIFLMDRSGSMQSPMSSQDTSQLRIQAAK 310
            +        + M+ F P++  D P      E I  +D S SM+     Q         AK
Sbjct: 852  E------SEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQ---------AK 896

Query: 311  ETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEIL 370
            +  +  L  +      NI  FG+ Y+  F      T  TM  A   +      +G T+  
Sbjct: 897  QIALHALSLVGEKQKVNIIQFGTGYKELFSYPKHITSNTM--AAEFIMSATPTMGNTDFW 954

Query: 371  APLQNIYRGPSIPGH-PLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSL 429
              L+  Y     P      + + +DG + D    ++ V+ +R   R F+ GIG   +  +
Sbjct: 955  KTLR--YLSLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHV 1012

Query: 430  IKGIARASGGTSEFITGKDR--MQSKALRTLKRSLQPVVEDVSLSW-HLPPGLSAKMLSP 486
            ++ +++   G  E+   K +   + +    + R   P    VS+ W  L P +   + +P
Sbjct: 1013 LRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAP 1072

Query: 487  EQT-VIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTI 545
             Q   +F   RL+ Y    G +P   T   +C    +Q K F   V+   + +      I
Sbjct: 1073 AQVPSLFLNDRLLVY----GFIPHC-TQATLCA--LIQEKEFRTMVS-TTELQKTTGTMI 1124

Query: 546  HRLAAKSLLQTKDMGL---RETPASDKKDAL-----NLSLESGVISSFTAFIAINK 593
            H+LAA++L++  + G+    ET    KK  L      LS E+ +I+ FT+F+A+ K
Sbjct: 1125 HKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEK 1180


>gi|222352129 von Willebrand factor A domain containing 5B2 [Homo
           sapiens]
          Length = 1242

 Score =  142 bits (357), Expect = 2e-33
 Identities = 133/568 (23%), Positives = 228/568 (40%), Gaps = 96/568 (16%)

Query: 14  PVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKI 73
           P+PL    V          V A L Y N +  P++  FV+P+ E   V  FEA   G+++
Sbjct: 12  PLPLTDSWVRACANGPCLSVRARLTYRNPQPQPVDGVFVYPLAEAEVVSGFEAEAAGRRV 71

Query: 74  VAELQDKMKARTNYEKAISQG---------HQAFLLEGDSSSRDVFSCNVGNLQPGSKAA 124
             +LQ + +++    +A+  G          Q  L+   + +R       G +       
Sbjct: 72  SFQLQSRRRSQAACCRALGPGLGTPTPRRCAQGHLVLDLAQARSTLVLPTGIIAAAGTMT 131

Query: 125 VTLKYVQELPLEADGALRFVLPAVLNPRYQ-----------FSGSSKDSCLNVKT----- 168
           VTL   +ELP   DG L   LP VL P                  S  SC  V +     
Sbjct: 132 VTLHSSRELPSRPDGVLHVALPTVLTPLAPPGPPGPPRPPGLCDDSPTSCFGVGSLQEEG 191

Query: 169 ----PIVPVEDL---------PYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQ 215
                +    D+         PYT S    +     +  ++S       +      ++A 
Sbjct: 192 LAWEELAAPRDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRADAPPHASSAAT 251

Query: 216 --VSLAAGHKFDRDVELLIYYNEVHTPSVVLEMG-------------------------- 247
             V+LA GH  DR +E+L++ +E H P ++LE G                          
Sbjct: 252 ICVTLAEGHHCDRALEILLHPSEPHQPHLMLEGGSLSSAEYEARVRARRDFQRLQRRDSD 311

Query: 248 -------MPNMKPGHLMGDPSAMVSFYPNIPEDQPSN---TCGEFIFLMDRSGSMQSPMS 297
                  +       ++ +P   +SF P++   +P +      E +FL+D S        
Sbjct: 312 GDRQVWFLQRRFHKDILLNPVLALSFCPDL-SSKPGHLGTATRELLFLLDSSSV------ 364

Query: 298 SQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRV 357
                     A K+ ++L +KSLP     N+  FG+  +  FPES   +   ++     +
Sbjct: 365 ----------AHKDAIVLAVKSLPPQTLINLAVFGTLVQPLFPESRPCSDDAVQLICESI 414

Query: 358 KLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGE--VTDTFSVIKEVRINRQKHR 415
           + +Q   G  ++LA L      P    +P QLF+ T        T   ++ +R +R   R
Sbjct: 415 ETLQVPSGPPDVLAALDWAVGQPQHRAYPRQLFLLTAASPMAATTHRTLELMRWHRGTAR 474

Query: 416 CFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHL 475
           CFSFG+G  T   L++G++  S G + F+    R+Q   ++ L+++L+P + D+S+ W +
Sbjct: 475 CFSFGLGP-TCHQLLQGLSALSRGQAYFLRPGQRLQPMLVQALRKALEPALSDISVDWFV 533

Query: 476 PPGLSAKMLSPEQTVIFRGQRLISYAQL 503
           P  + A +   E   ++ G +L+ Y  L
Sbjct: 534 PDTVEALLTPREIPALYPGDQLLGYCSL 561



 Score = 33.5 bits (75), Expect = 0.78
 Identities = 15/34 (44%), Positives = 18/34 (52%)

Query: 725  WATILAVIWLHSNGKDLKCEWELLERKAVAWMRA 758
            WAT +A+ WL         EWEL   KA  W+RA
Sbjct: 1167 WATAVALAWLEHRCAAAFDEWELTAAKADCWLRA 1200


>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
          Length = 911

 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 97/488 (19%), Positives = 186/488 (38%), Gaps = 84/488 (17%)

Query: 17  LKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAE 76
           ++S+ V+  +    A    T    N      E  F   + + + +  F    DG   + +
Sbjct: 53  IRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGD 112

Query: 77  LQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLE 136
           ++DK+ A   Y KA   G  A L+     + + F+ ++  + P SK    L Y + L   
Sbjct: 113 IKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHL-TVNPQSKVTFQLTYEEVLKRN 171

Query: 137 ADGALRFVLPAVLNPR------------YQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVA 184
               +++ +   + P+            ++  G SK   L+ +   +P E    T+    
Sbjct: 172 H---MQYEIVIKVKPKQLVHHFEIDVDIFEPQGISK---LDAQASFLPKELAAQTIKKSF 225

Query: 185 TIDSQHGIEKV----QSNCPLSPTEYL-GEDKTSAQVSLAAGHKFDRDVELLIYYNEVHT 239
           +    H + +     Q +CP   T  L G  K +  VS       D+  +LL+  N    
Sbjct: 226 SGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSR------DKICDLLVANNHF-- 277

Query: 240 PSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQ 299
                          H    P  + +   N+            +F++D SGSM+      
Sbjct: 278 --------------AHFFA-PQNLTNMNKNV------------VFVIDISGSMRGQ---- 306

Query: 300 DTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKL 359
                +++  KE L+ +L  +  G YF++  FG+  ++     V+ ++  ++ A   V+ 
Sbjct: 307 -----KVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRG 361

Query: 360 MQAD---------LGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGE----VTDTFSVIKE 406
              D         L G EIL  +Q     P +  H   L + TDG+    VTD   ++K 
Sbjct: 362 FSLDEATNLNGGLLRGIEILNQVQESL--PELSNHASILIMLTDGDPTEGVTDRSQILKN 419

Query: 407 VR-INRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPV 465
           VR   R +   ++ G G     + ++ ++  + G ++ I        +      +  +P+
Sbjct: 420 VRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPL 479

Query: 466 VEDVSLSW 473
           + DV L +
Sbjct: 480 LVDVDLQY 487


>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
          Length = 930

 Score = 67.4 bits (163), Expect = 5e-11
 Identities = 130/638 (20%), Positives = 251/638 (39%), Gaps = 84/638 (13%)

Query: 9   TLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALV 68
           T  +  + + S++V   +    A    T    N      EA F   + + + + +F  ++
Sbjct: 27  TAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMII 86

Query: 69  DGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLK 128
           DG      +++K +A+  Y  A+++G  A L++    + + F  +V ++ P +K    L 
Sbjct: 87  DGMTYPGIIKEKAEAQAQYSAAVAKGKSAGLVKATGRNMEQFQVSV-SVAPNAKITFELV 145

Query: 129 YVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTP----IVPVEDLPYTLSMVA 184
           Y +EL     G    +L   + P+        D  +++  P     +  E    T  +V 
Sbjct: 146 Y-EELLKRRLGVYELLLK--VRPQQLVKHLQMD--IHIFEPQGISFLETESTFMTNQLVD 200

Query: 185 TIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVL 244
            + +     K +++    PT    +     Q ++  G+       L+I Y+        +
Sbjct: 201 ALTTWQN--KTKAHIRFKPTLSQQQKSPEQQETVLDGN-------LIIRYDVDRA----I 247

Query: 245 EMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQDTSQL 304
             G   ++ G+ +        F P      P N     +F++D+SGSM         S  
Sbjct: 248 SGGSIQIENGYFVH------YFAPEGLTTMPKNV----VFVIDKSGSM---------SGR 288

Query: 305 RIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADL 364
           +IQ  +E LI +L  L     FN+  F +      P  V  + + + +A      +QA L
Sbjct: 289 KIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSLVPASAENVNKARSFAAGIQA-L 347

Query: 365 GGTEI-------LAPLQNIYRGPSIPGHPLQLFV-FTDGEVTDTFSVIKEVRINRQ---- 412
           GGT I       +  L +  +   +P   + L +  TDG+ T   +  + ++ N +    
Sbjct: 348 GGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDPTVGETNPRSIQNNVREAVS 407

Query: 413 -KHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDV-- 469
            ++  F  G G   S + ++ +A  +GG +  I       S +   L+   Q V   +  
Sbjct: 408 GRYSLFCLGFGFDVSYAFLEKLALDNGGLARRI----HEDSDSALQLQDFYQEVANPLLT 463

Query: 470 SLSWHLPPGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFED 529
           ++++  P     ++      ++F+G  ++   +L  R P    T  V  K   Q  TF+ 
Sbjct: 464 AVTFEYPSNAVEEVTQNNFRLLFKGSEMVVAGKLQDRGPDV-LTATVSGKLPTQNITFQT 522

Query: 530 KVTFPLQ------PKPDVNLTIHRLAAKSLLQTKDMGLRETPASD------KKDALNLSL 577
           + +   Q      PK   +  + RL A   L  + +  +   ASD      +  ALNLSL
Sbjct: 523 ESSVAEQEAEFQSPKYIFHNFMERLWA--YLTIQQLLEQTVSASDADQQALRNQALNLSL 580

Query: 578 ESGVISSFTAFIAINKE-------LNKPVQGPLAHRDV 608
               ++  T+ +    +         KP++G   +R+V
Sbjct: 581 AYSFVTPLTSMVVTKPDDQEQSQVAEKPMEGESRNRNV 618


>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
          Length = 1313

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 141/635 (22%), Positives = 249/635 (39%), Gaps = 94/635 (14%)

Query: 8   LTLHREPVP--------LKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDS 59
           LT    PVP        + S S+   +    A    T    N      EA F   +   +
Sbjct: 20  LTYQGPPVPASSSTKLLMTSYSMRSTVVSRYAHTLVTSVLFNPHAEAHEAIFDLDLPHLA 79

Query: 60  AVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQP 119
            + +F   ++ K  +AE+++K +A+  YE+A  QG  A  +       + F  +  +L  
Sbjct: 80  FISNFTMTINNKVYIAEVKEKHQAKKIYEEAHQQGKTAAHVGIRDRESEKFRIST-SLAA 138

Query: 120 GSKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYT 179
           G++   +L Y +EL     G  + V+   L P       S +  ++ +T I  V   P  
Sbjct: 139 GTEVTFSLAY-EELLQRHQGQYQLVVS--LRPGQLVKRLSIEVTVSERTGISYVHIPPLR 195

Query: 180 LSMVAT------IDSQHG--IEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELL 231
              + T      +DS     IE+ ++   ++    L +  + +   + A        + L
Sbjct: 196 TGRLRTNAHASEVDSPPSTRIERGETCVRITYCPTLQDQSSISGSGIMA--------DFL 247

Query: 232 IYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVSFYPN--IPEDQPSNTCGEFIFLMDRS 289
           + Y+      VV+E          ++GD      ++ +   P   P       +F++D S
Sbjct: 248 VQYD------VVME---------DIIGDVQIYDDYFIHYFAPRGLPPME-KNVVFVIDVS 291

Query: 290 GSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEAC-FPESVKYTQQ 348
            SM            +++  K  + ++L  L    YFNI  F  +        S++ T Q
Sbjct: 292 SSMFG---------TKMEQTKTAMNVILSDLQANDYFNIISFSDTVNVWKAGGSIQATIQ 342

Query: 349 TMEEALGRVKLMQADLGGTEILAPL-----------QNIYRGPSIPGHPLQLFVFTDGEV 397
            +  A   +  M+AD G T++ + L           Q   RGPS+   PL +F+ TDGE 
Sbjct: 343 NVHSAKDYLHCMEAD-GWTDVNSALLAAASVLNHSNQEPGRGPSVGRIPLIIFL-TDGEP 400

Query: 398 T---DTFSVIKEVRINRQKHR--CFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQS 452
           T    T SVI         HR   FS   G+    +L++ ++  + G +  I  +D   +
Sbjct: 401 TAGVTTPSVILSNVRQALGHRVSLFSLAFGDDADFTLLRRLSLENRGIARRIY-EDTDAA 459

Query: 453 KALRTLKRSL-QPVVEDVSLSW-HLPPGLSAKMLSPE----QTVIFRGQRLISYAQLTGR 506
             L+ L   +  P++ DV L++     G S   + P       ++  GQ      +L   
Sbjct: 460 LQLKGLYEEISMPLLADVRLNYLGGLVGASPWAVFPNYFGGSELVVAGQVQPGKQELGIH 519

Query: 507 MPAAETTGEVCLKYTLQGKTFEDKVTF--PLQPKPDVNLTIHRLAA--------KSLLQT 556
           + A     ++ + +  +G T   +  F  P +P P+V   I RL A         +  Q 
Sbjct: 520 LAARGPKDQLLVAHHSEGATNNSQKAFGCPGEPAPNVAHFIRRLWAYVTIGELLDAHFQA 579

Query: 557 KDMGLRETPASDKKDALNLSLESGVISSFTAFIAI 591
           +D   R   A+     LNLSLE   ++  T+ + +
Sbjct: 580 RDTTTRHLLAA---KVLNLSLEYNFVTPLTSLVMV 611


>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
           [Homo sapiens]
          Length = 890

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 86/423 (20%), Positives = 152/423 (35%), Gaps = 60/423 (14%)

Query: 36  TLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGH 95
           T+   N      E  F   + + + + +F   +DG      +++K  A+  YEKA+SQG 
Sbjct: 64  TMRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGK 123

Query: 96  QAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQF 155
            A L++      + F+ +V N+  GSK    L Y +EL     G     L          
Sbjct: 124 TAGLVKASGRKLEKFTVSV-NVAAGSKVTFELTY-EELLKRHKGKYEMYLK--------- 172

Query: 156 SGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQ 215
                          V  + L     +   I    GI  + +       + LG   T + 
Sbjct: 173 ---------------VQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKS- 216

Query: 216 VSLAAGH-----KFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVSFY-PN 269
            S   GH       D+        + +      +   +    PG++       V F+ P 
Sbjct: 217 FSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNRESPGNVQIVNGYFVHFFAPQ 276

Query: 270 IPEDQPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIY 329
                P N      F++D SGSM         +  +++  KE L+ +L+ +    Y N  
Sbjct: 277 GLPVVPKNVA----FVIDISGSM---------AGRKLEQTKEALLRILEDMQEEDYLNFI 323

Query: 330 GFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEI-------LAPLQNIYRGPSI 382
            F           V+ T + ++EA   VK M+ D G T I       ++ L        I
Sbjct: 324 LFSGDVSTWKEHLVQATPENLQEARTFVKSME-DKGMTNINDGLLRGISMLNKAREEHRI 382

Query: 383 PGHPLQLFV-FTDGEVTDTFSVIKEVRINRQ-----KHRCFSFGIGEGTSTSLIKGIARA 436
           P     + +  TDG+     S  ++++ N +     K   ++ G G   + + ++ +A  
Sbjct: 383 PERSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALE 442

Query: 437 SGG 439
           + G
Sbjct: 443 NHG 445


>gi|218505703 von Willebrand factor A domain containing 3A [Homo
            sapiens]
          Length = 1184

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 44/172 (25%), Positives = 74/172 (43%), Gaps = 20/172 (11%)

Query: 285  LMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGC-YFNIYGFGSSYEACFPESV 343
            L+D SGSM   +          Q   E ++L+ + L   C  FN+  F  S+++     V
Sbjct: 963  LLDTSGSMGPYLQ---------QVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLV 1013

Query: 344  KYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFS- 402
            + T     EA+  V  +QA  G T IL  L   +    + G    L++ TDG+   + S 
Sbjct: 1014 ETTDAACHEAMQWVTHLQAQ-GSTSILQALLKAFSFHDLEG----LYLLTDGKPDTSCSL 1068

Query: 403  VIKEVRINRQKH----RCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRM 450
            V+ EV+  R+K        S    +  +   ++ +A  +GG      G+D +
Sbjct: 1069 VLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTL 1120


>gi|27262622 neuron navigator 1 [Homo sapiens]
          Length = 1874

 Score = 34.7 bits (78), Expect = 0.35
 Identities = 55/271 (20%), Positives = 106/271 (39%), Gaps = 32/271 (11%)

Query: 371  APLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLI 430
            A    I R  SIP H     +++  ++  T S+ +     R K    S    + T     
Sbjct: 1004 ATTPRITRSNSIPTHEAAFELYSGSQMGSTLSLAE-----RPKGMIRSGSFRDPTDDVHG 1058

Query: 431  KGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLSAKMLSPEQTV 490
              ++ AS  +S + + ++RMQS+ +R L+R L+   E V+        L++++ +    V
Sbjct: 1059 SVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVAT-------LTSQLSANANLV 1111

Query: 491  IFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTIHRLAA 550
                Q L++   +T R+     T E   +   +     + + F  +   +    I     
Sbjct: 1112 AAFEQSLVN---MTSRLRHLAETAE---EKDTELLDLRETIDFLKKKNSEAQAVIQGALN 1165

Query: 551  KSLLQTKDMGLRETPASDKKDALN-LSLESGVISSFTAFIAINKE-------------LN 596
             S    K++ ++   +SD   +LN ++  S + SS  A     K+             + 
Sbjct: 1166 ASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWLRSSFNKAFSIK 1225

Query: 597  KPVQGPLAHRDVPRPILLGASAPLKIKCQSG 627
            K  +   ++ D+       +SAP   K Q G
Sbjct: 1226 KGPKSASSYSDIEEIATPDSSAPSSPKLQHG 1256


>gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]
          Length = 1531

 Score = 33.5 bits (75), Expect = 0.78
 Identities = 34/124 (27%), Positives = 48/124 (38%), Gaps = 19/124 (15%)

Query: 477  PGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQ 536
            P LS K L P+++V+               + A +  G V L  +     F D+      
Sbjct: 1362 PKLSNKELKPQKSVV-------------SDLEADDVKGSVPLSSSPPATHFPDETEIT-N 1407

Query: 537  PKPDVNLTIHRLAAKSLLQTKDMGL--RETPASDKKDALNLSLESGVISSFTAFIAINKE 594
            P P  N+T+ + AAKS   T   G   R  P   K+D    +L SGV          N+ 
Sbjct: 1408 PVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKGTKRDP---ALNSGVSQKPDPAKTKNRR 1464

Query: 595  LNKP 598
              KP
Sbjct: 1465 KRKP 1468


>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
           subunit [Homo sapiens]
          Length = 1091

 Score = 32.0 bits (71), Expect = 2.3
 Identities = 49/206 (23%), Positives = 84/206 (40%), Gaps = 20/206 (9%)

Query: 274 QPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGS 333
           Q + +  + + L+D SGSM+          LR+  AK+T+  +L +L    +FNI  +  
Sbjct: 249 QAATSPKDVVILVDVSGSMKG---------LRLTIAKQTVSSILDTLGDDDFFNIIAYNE 299

Query: 334 S---YEACFPESVKYTQQTMEEALGR--VKLMQADLGGTEI-LAPLQNIYRGPSIPGH-- 385
                E C   ++    +T +E       KL    +G  +I L    NI    +  G   
Sbjct: 300 ELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGS 359

Query: 386 --PLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIG-EGTSTSLIKGIARASGGTSE 442
                + + TDG V    ++  +     +K R F++ IG E      +K +A A+ G   
Sbjct: 360 ICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFT 419

Query: 443 FITGKDRMQSKALRTLKRSLQPVVED 468
            I+    +Q   +  L    +P V D
Sbjct: 420 QISTLADVQENVMEYLHVLSRPKVID 445


>gi|31317228 early growth response 3 [Homo sapiens]
          Length = 387

 Score = 31.2 bits (69), Expect = 3.9
 Identities = 30/143 (20%), Positives = 65/143 (45%), Gaps = 16/143 (11%)

Query: 194 KVQSNCPLSPTEYLGE--DKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNM 251
           K+    P++ +  L +  D    +   +A + F    + +++YN++ T +V +++G+ N 
Sbjct: 4   KLAEKLPVTMSSLLNQLPDNLYPEEIPSALNLFSGSSDSVVHYNQMATENV-MDIGLTNE 62

Query: 252 KP-------GHLMGDP-SAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSP-----MSS 298
           KP       G     P +  V++      D PSN C + I  +  +G +  P     +S+
Sbjct: 63  KPNPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGALST 122

Query: 299 QDTSQLRIQAAKETLILLLKSLP 321
           Q ++   +Q  +  +  +  +LP
Sbjct: 123 QTSTASMVQPPQGDVEAMYPALP 145


>gi|46249395 Ras-related GTP binding B short isoform [Homo sapiens]
          Length = 346

 Score = 30.8 bits (68), Expect = 5.1
 Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 1/112 (0%)

Query: 136 EADGALRFVLP-AVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEK 194
           E +G+L +VLP   +  +    G S     ++++ I        T  + ATID +H   +
Sbjct: 25  EPEGSLGWVLPNTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATIDVEHSHVR 84

Query: 195 VQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEM 246
              N  L+  +  G+D        +      R+VE+LIY  +V +  +  +M
Sbjct: 85  FLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDM 136


>gi|42741659 ATP-binding cassette, subfamily B, member 1 [Homo
            sapiens]
          Length = 1280

 Score = 30.0 bits (66), Expect = 8.7
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 18/114 (15%)

Query: 653  KTFQMDDYSLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIM 712
            KT  +D YS  GL+ +  + +  FGE     ++++      +    D+  + G+SLE + 
Sbjct: 1014 KTPLIDSYSTEGLMPNTLEGNVTFGE-----VVFN------YPTRPDIPVLQGLSLE-VK 1061

Query: 713  AAQPAELVDSSGWATILAVIWLHS-----NGKDLKCEWELLERKAVAWMRAHAG 761
              Q   LV SSG      V  L        GK L  + + ++R  V W+RAH G
Sbjct: 1062 KGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVL-LDGKEIKRLNVQWLRAHLG 1114


>gi|239749462 PREDICTED: similar to ubiquitin protein ligase E3
            component n-recognin 5 isoform 2 [Homo sapiens]
          Length = 2277

 Score = 30.0 bits (66), Expect = 8.7
 Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 1/98 (1%)

Query: 218  LAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVS-FYPNIPEDQPS 276
            L AG + DRD +     +    P      G P+  P  L     A+    YP +   QP+
Sbjct: 1831 LRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGERLYPRVQAMQPA 1890

Query: 277  NTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLI 314
                    L+D   S  S ++S+D+ + R+  A E +I
Sbjct: 1891 FASKITGMLLDYPSSAASLLASEDSLRARVDEAMELII 1928


>gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3
            component n-recognin 5 isoform 1 [Homo sapiens]
          Length = 2796

 Score = 30.0 bits (66), Expect = 8.7
 Identities = 26/98 (26%), Positives = 41/98 (41%), Gaps = 1/98 (1%)

Query: 218  LAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVS-FYPNIPEDQPS 276
            L AG + DRD +     +    P      G P+  P  L     A+    YP +   QP+
Sbjct: 2350 LRAGSRRDRDRDFRRQLSIDTRPFRPASEGNPSDDPEPLPAHRQALGERLYPRVQAMQPA 2409

Query: 277  NTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLI 314
                    L+D   S  S ++S+D+ + R+  A E +I
Sbjct: 2410 FASKITGMLLDYPSSAASLLASEDSLRARVDEAMELII 2447


>gi|13540533 N-acetylneuraminate pyruvate lyase [Homo sapiens]
          Length = 320

 Score = 30.0 bits (66), Expect = 8.7
 Identities = 19/71 (26%), Positives = 32/71 (45%), Gaps = 3/71 (4%)

Query: 392 FTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQ 451
           F+D ++ D    + +   NRQ+   F FG+ E   ++L+ G   A G T  ++  K    
Sbjct: 174 FSDTDLLDFGQCVDQ---NRQQQFAFLFGVDEQLLSALVMGATGAVGSTYNYLGKKTNQM 230

Query: 452 SKALRTLKRSL 462
            +A      SL
Sbjct: 231 LEAFEQKDFSL 241


>gi|148596992 heart alpha-kinase [Homo sapiens]
          Length = 2170

 Score = 30.0 bits (66), Expect = 8.7
 Identities = 69/318 (21%), Positives = 125/318 (39%), Gaps = 47/318 (14%)

Query: 154  QFSGSSKDSCLNVK---TPIVPVEDLPYTLSMVATID---SQHGIEKVQ-SNCPLSPTEY 206
            Q S +S  +C + K   + + P+    +TL++  T     +   + KV+ S  PL+ T +
Sbjct: 867  QVSETSVSTCKSSKDGNSVMSPLFTSTFTLNISHTASEGATGENLAKVENSTYPLASTVH 926

Query: 207  LGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVSF 266
             G+++ S   S         + +LL   N    P V  + G  +  P     D +A  + 
Sbjct: 927  AGQEQPSPSNSGGLD-----ETQLLSSENN---PLVQFKEG-GDKSPSPSAADTTATPAS 977

Query: 267  YPNI---PEDQPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIG 323
            Y +I   P ++P+        L   +   Q+   ++DTS + I         L  S+P  
Sbjct: 978  YSSIVSFPWEKPTT-------LTANNECFQATRETEDTSTVTIATEVHPAKYLAVSIPED 1030

Query: 324  CYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIP 383
             +          E  FP +   + + + +   +V+L    L G  I +  + + R PS+P
Sbjct: 1031 KH------AGGTEERFPRA---SHEKVSQFPSQVQLDHI-LSGATIKSTKELLCRAPSVP 1080

Query: 384  GHPLQLFVFTDGE--------VTDTFSVIKEVRINRQKHRCFSFGIGE-GTSTSLIKGIA 434
            G P  +    +GE          D  S  K   ++R   R +     E G+ T   +G+ 
Sbjct: 1081 GVPHHVLQLPEGEGFCSNSPLQVDNLSGDKSQTVDRADFRSYEENFQERGSETK--QGVQ 1138

Query: 435  RASGGTSEFITGKDRMQS 452
            + S      ++  D  QS
Sbjct: 1139 QQSLSQQGSLSAPDFQQS 1156


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,288,119
Number of Sequences: 37866
Number of extensions: 1393340
Number of successful extensions: 2958
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2932
Number of HSP's gapped (non-prelim): 32
length of query: 786
length of database: 18,247,518
effective HSP length: 110
effective length of query: 676
effective length of database: 14,082,258
effective search space: 9519606408
effective search space used: 9519606408
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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