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Search of human proteins with 193804862
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|193804862 synaptotagmin-like 4 [Homo sapiens]
(671 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 1351 0.0
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 1351 0.0
gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] 496 e-140
gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens] 496 e-140
gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] 489 e-138
gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens] 301 1e-81
gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens] 298 8e-81
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] 298 1e-80
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] 298 1e-80
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens] 294 2e-79
gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens] 294 2e-79
gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens] 289 7e-78
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] 285 1e-76
gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens] 284 2e-76
gi|14249614 synaptotagmin-like 1 [Homo sapiens] 263 5e-70
gi|110227631 synaptotagmin-like 3 [Homo sapiens] 213 4e-55
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 173 5e-43
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 173 5e-43
gi|211059429 synaptotagmin II [Homo sapiens] 146 7e-35
gi|31543670 synaptotagmin II [Homo sapiens] 146 7e-35
gi|92859638 synaptotagmin V [Homo sapiens] 143 6e-34
gi|6005997 double C2-like domains, beta [Homo sapiens] 139 1e-32
gi|209447073 synaptotagmin I [Homo sapiens] 135 2e-31
gi|5032139 synaptotagmin I [Homo sapiens] 135 2e-31
gi|209447070 synaptotagmin I [Homo sapiens] 135 2e-31
gi|38570146 synaptotagmin VII [Homo sapiens] 131 2e-30
gi|238550198 synaptotagmin III [Homo sapiens] 130 5e-30
gi|238550196 synaptotagmin III [Homo sapiens] 130 5e-30
gi|14150054 synaptotagmin III [Homo sapiens] 130 5e-30
gi|39752671 synaptotagmin X [Homo sapiens] 125 1e-28
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 1351 bits (3496), Expect = 0.0
Identities = 671/671 (100%), Positives = 671/671 (100%)
Query: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60
MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD
Sbjct: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60
Query: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 120
RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY
Sbjct: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 120
Query: 121 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 180
DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS
Sbjct: 121 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 180
Query: 181 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 240
VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE
Sbjct: 181 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 240
Query: 241 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 300
TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL
Sbjct: 241 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 300
Query: 301 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 360
NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI
Sbjct: 301 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 360
Query: 361 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 420
AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI
Sbjct: 361 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 420
Query: 421 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 480
NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL
Sbjct: 421 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 480
Query: 481 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 540
HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA
Sbjct: 481 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 540
Query: 541 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 600
AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT
Sbjct: 541 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 600
Query: 601 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660
VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL
Sbjct: 601 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660
Query: 661 RSSMAKQKLGL 671
RSSMAKQKLGL
Sbjct: 661 RSSMAKQKLGL 671
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 1351 bits (3496), Expect = 0.0
Identities = 671/671 (100%), Positives = 671/671 (100%)
Query: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60
MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD
Sbjct: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60
Query: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 120
RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY
Sbjct: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 120
Query: 121 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 180
DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS
Sbjct: 121 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 180
Query: 181 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 240
VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE
Sbjct: 181 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 240
Query: 241 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 300
TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL
Sbjct: 241 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 300
Query: 301 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 360
NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI
Sbjct: 301 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 360
Query: 361 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 420
AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI
Sbjct: 361 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 420
Query: 421 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 480
NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL
Sbjct: 421 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 480
Query: 481 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 540
HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA
Sbjct: 481 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 540
Query: 541 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 600
AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT
Sbjct: 541 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 600
Query: 601 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660
VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL
Sbjct: 601 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660
Query: 661 RSSMAKQKLGL 671
RSSMAKQKLGL
Sbjct: 661 RSSMAKQKLGL 671
>gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 496 bits (1277), Expect = e-140
Identities = 296/732 (40%), Positives = 420/732 (57%), Gaps = 70/732 (9%)
Query: 2 SELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDR 61
SE ++LSFL + EK++IL VL+RDE ++K ++KRIR+LKNELLE KR+ K +Q + R
Sbjct: 5 SEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGK--TQQEASR 62
Query: 62 TCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYD 121
C C +LG + + + C+ C+ VCR+CR+ NG+W+C VC K +L+ TG+WF++
Sbjct: 63 VCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122
Query: 122 QKVNRFAYRT--GSEIIRMS-LRHKPAVSKRETVGQSLLHQTQMGDIWP--GRKIIQERQ 176
+K RF G++++R S LR P + ++ Q+ + D P G+K +
Sbjct: 123 EKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQT-RQDAEKSDTSPVAGKKASHDGP 181
Query: 177 KEPSVLFE-----------VPKLKSGKS-ALEAESESLDSFT----ADSDSTSRRDSLDK 220
K L PK +G+S +L+ + + S +D ST D D+
Sbjct: 182 KRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQ 241
Query: 221 ------------SGLFPEWKKMSAPKSQVEKET---QPGGQNVVFVDEGEMIFKKNTRKI 265
+G+ P + AP ++ + G +N + + E ++ T+
Sbjct: 242 EPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSH 301
Query: 266 LR---------------PSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEE 310
R S+ ++S +DL ++ RSKSVPG EE E
Sbjct: 302 RRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETE 361
Query: 311 EDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQT 370
E ID LV + + SG S +++ SMMS+YSE GD+GN+ V+G I + Y +T
Sbjct: 362 ESIDALVS-SQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT 420
Query: 371 QSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRY 430
L + VK C LA DE K+R++ YVK+YLLPDKSR KRKT I+ T NP ++ETL+Y
Sbjct: 421 GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKY 479
Query: 431 EIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPT 490
I + L RTLQ SVWH+ RFGRN+FLGE EI DSW + D L K+
Sbjct: 480 TISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDI 539
Query: 491 GLPSHKGELVVSLKYIP-------------ASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
GL +KGEL V L+YIP +KT G +K+S GG L+V+IKEAKN
Sbjct: 540 GL-QYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKN 598
Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
LTA K+GGTSDSFVKGYLLP +KA+K KT V+KK++NP +NHTF+++G+ +D++++CL
Sbjct: 599 LTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCL 658
Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGT 657
ELT+WD+E +SN FLGGVRL G+G+S+G+ VDWMDS GEE LWQKM PG+ EG
Sbjct: 659 ELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGV 718
Query: 658 LQLRSSMAKQKL 669
L LRSSM K +L
Sbjct: 719 LMLRSSMGKCRL 730
>gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens]
Length = 730
Score = 496 bits (1277), Expect = e-140
Identities = 296/732 (40%), Positives = 420/732 (57%), Gaps = 70/732 (9%)
Query: 2 SELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDR 61
SE ++LSFL + EK++IL VL+RDE ++K ++KRIR+LKNELLE KR+ K +Q + R
Sbjct: 5 SEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGK--TQQEASR 62
Query: 62 TCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYD 121
C C +LG + + + C+ C+ VCR+CR+ NG+W+C VC K +L+ TG+WF++
Sbjct: 63 VCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122
Query: 122 QKVNRFAYRT--GSEIIRMS-LRHKPAVSKRETVGQSLLHQTQMGDIWP--GRKIIQERQ 176
+K RF G++++R S LR P + ++ Q+ + D P G+K +
Sbjct: 123 EKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQT-RQDAEKSDTSPVAGKKASHDGP 181
Query: 177 KEPSVLFE-----------VPKLKSGKS-ALEAESESLDSFT----ADSDSTSRRDSLDK 220
K L PK +G+S +L+ + + S +D ST D D+
Sbjct: 182 KRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQ 241
Query: 221 ------------SGLFPEWKKMSAPKSQVEKET---QPGGQNVVFVDEGEMIFKKNTRKI 265
+G+ P + AP ++ + G +N + + E ++ T+
Sbjct: 242 EPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSH 301
Query: 266 LR---------------PSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEE 310
R S+ ++S +DL ++ RSKSVPG EE E
Sbjct: 302 RRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETE 361
Query: 311 EDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQT 370
E ID LV + + SG S +++ SMMS+YSE GD+GN+ V+G I + Y +T
Sbjct: 362 ESIDALVS-SQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT 420
Query: 371 QSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRY 430
L + VK C LA DE K+R++ YVK+YLLPDKSR KRKT I+ T NP ++ETL+Y
Sbjct: 421 GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKY 479
Query: 431 EIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPT 490
I + L RTLQ SVWH+ RFGRN+FLGE EI DSW + D L K+
Sbjct: 480 TISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDI 539
Query: 491 GLPSHKGELVVSLKYIP-------------ASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
GL +KGEL V L+YIP +KT G +K+S GG L+V+IKEAKN
Sbjct: 540 GL-QYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKN 598
Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
LTA K+GGTSDSFVKGYLLP +KA+K KT V+KK++NP +NHTF+++G+ +D++++CL
Sbjct: 599 LTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCL 658
Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGT 657
ELT+WD+E +SN FLGGVRL G+G+S+G+ VDWMDS GEE LWQKM PG+ EG
Sbjct: 659 ELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGV 718
Query: 658 LQLRSSMAKQKL 669
L LRSSM K +L
Sbjct: 719 LMLRSSMGKCRL 730
>gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens]
Length = 752
Score = 489 bits (1258), Expect = e-138
Identities = 300/753 (39%), Positives = 423/753 (56%), Gaps = 90/753 (11%)
Query: 2 SELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDR 61
SE ++LSFL + EK++IL VL+RDE ++K ++KRIR+LKNELLE KR+ K +Q + R
Sbjct: 5 SEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGK--TQQEASR 62
Query: 62 TCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYD 121
C C +LG + + + C+ C+ VCR+CR+ NG+W+C VC K +L+ TG+WF++
Sbjct: 63 VCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122
Query: 122 QKVNRFAYRT--GSEIIRMS-LRHKPAVSKRETVGQSLLHQTQMGDIWP--GRKIIQERQ 176
+K RF G++++R S LR P + ++ Q+ + D P G+K +
Sbjct: 123 EKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTR-QDAEKSDTSPVAGKKASHDGP 181
Query: 177 KEPSVLFE-----------VPKLKSGKS-ALEAESESLDSFTA----DSDSTSRRDSLDK 220
K L PK +G+S +L+ + + S + D ST D D+
Sbjct: 182 KRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQ 241
Query: 221 ------------SGLFPEWKKMSAPKSQVEKET---QPGGQNVVFVDEGEMIFKKNTRKI 265
+G+ P + AP ++ + G +N + + E ++ T+
Sbjct: 242 EPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSH 301
Query: 266 LR---------------PSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEE 310
R S+ ++S +DL ++ RSKSVPG EE E
Sbjct: 302 RRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETE 361
Query: 311 EDIDHLVK------LHRQKLARS-SMQSGSSM--------------STIGSMMSIYSEAG 349
E ID LV HR S S Q+GS +++ SMMS+YSE G
Sbjct: 362 ESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSETG 421
Query: 350 DFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQG 409
D+GN+ V+G I + Y +T L + VK C LA DE K+R++ YVK+YLLPDKSR
Sbjct: 422 DYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNN 481
Query: 410 KRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWK 469
KRKT I+ T NP ++ETL+Y I + L RTLQ SVWH+ RFGRN+FLGE EI DSW
Sbjct: 482 KRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 540
Query: 470 LDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIP-------------ASKTPVGGD 516
+ D L K+ GL +KGEL V L+YIP +KT G
Sbjct: 541 FENPTDEWFVLQPKVEFAPDIGL-QYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGK 599
Query: 517 RKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNP 576
+K+S GG L+V+IKEAKNLTA K+GGTSDSFVKGYLLP +KA+K KT V+KK++NP
Sbjct: 600 KKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNP 659
Query: 577 HYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDST 636
+NHTF+++G+ +D++++CLELT+WD+E +SN FLGGVRL G+G+S+G+ VDWMDS
Sbjct: 660 QWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQ 719
Query: 637 GEEVSLWQKMRQYPGSWAEGTLQLRSSMAKQKL 669
GEE LWQKM PG+ EG L LRSSM K +L
Sbjct: 720 GEEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 752
>gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens]
Length = 1256
Score = 301 bits (771), Expect = 1e-81
Identities = 188/535 (35%), Positives = 287/535 (53%), Gaps = 40/535 (7%)
Query: 153 GQSLLHQTQMGDIWPGRKIIQERQKEPSVLFEVPKLKSGKSALE---------------- 196
GQ L + G+ + + RQ P ++ + K+ K L
Sbjct: 727 GQGTLQEPGFGEASEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEG 786
Query: 197 -AESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQPGGQNVVFVDEGE 255
+ES+ D T+ + + R S + P K + +S K +++ +
Sbjct: 787 FSESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLE--RSAARKMPSKSLEDISSDSSNQ 844
Query: 256 MIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEEDI-D 314
+++R +E S + +P++ L SKSVP D ++ E + +
Sbjct: 845 AKVDNQPEELVRSAEDV-STVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASE 903
Query: 315 HLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSLKYE 367
+L R K + SS+ + SS S + GS+MS+YS GDFGN+ V G I F+++Y
Sbjct: 904 SSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYV 961
Query: 368 QQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDET 427
+ + L V V +C LA AD K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y+E
Sbjct: 962 ESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEI 1021
Query: 428 LRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAE 487
LRY+I + +L + L S+WH F RN+FLGE E+ +++W D K + L +
Sbjct: 1022 LRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT 1081
Query: 488 SPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGT 546
+P L + ++GE+ ++L+Y+P PV G + + GE+ +W+KE +L + G
Sbjct: 1082 APVALEAENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR-GSH 1133
Query: 547 SDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREP 606
+SFVK +LP ++ S++KT + KT NP +NHT VY+G R EDL C+ELTVWD
Sbjct: 1134 LNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYK 1193
Query: 607 LASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661
L +N FLGG+R+G GTG S G VDWMDST EEV+LW+KM P +W E TL LR
Sbjct: 1194 L-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1247
>gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens]
Length = 1272
Score = 298 bits (764), Expect = 8e-81
Identities = 189/538 (35%), Positives = 284/538 (52%), Gaps = 23/538 (4%)
Query: 133 SEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLFEVPKLKSGK 192
SE I +S +P + + ++ P K +E +KE F G
Sbjct: 740 SEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEG---FSESDFSDGN 796
Query: 193 SALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQPGGQNVVFVD 252
++ AES S + + S + + K + S + + Q V
Sbjct: 797 TSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVR 856
Query: 253 EGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEED 312
E K + + + S + +P++ L SKSVP D ++ E +
Sbjct: 857 SAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDT 916
Query: 313 I-DHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSL 364
+ +L R K + SS+ + SS S + GS+MS+YS GDFGN+ V G I F++
Sbjct: 917 ASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAI 974
Query: 365 KYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLY 424
+Y + + L V V +C LA AD K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y
Sbjct: 975 EYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVY 1034
Query: 425 DETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKI 484
+E LRY+I + +L + L S+WH F RN+FLGE E+ +++W D K + L +
Sbjct: 1035 NEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLK 1094
Query: 485 SAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKA 543
+P L + ++GE+ ++L+Y+P PV G + + GE+ +W+KE +L +
Sbjct: 1095 RKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR- 1146
Query: 544 GGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWD 603
G +SFVK +LP ++ S++KT + KT NP +NHT VY+G R EDL C+ELTVWD
Sbjct: 1147 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 1206
Query: 604 REPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661
L +N FLGG+R+G GTG S G VDWMDST EEV+LW+KM P +W E TL LR
Sbjct: 1207 HYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1263
>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
Length = 935
Score = 298 bits (762), Expect = 1e-80
Identities = 169/409 (41%), Positives = 246/409 (60%), Gaps = 25/409 (6%)
Query: 267 RPSEYTKSVIDL-----RPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEEDI-DHLVKLH 320
+P E +S D+ +P++ L SKSVP D ++ E + + +L
Sbjct: 529 QPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLS 588
Query: 321 RQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSL 373
R K + SS+ + SS S + GS+MS+YS GDFGN+ V G I F+++Y + + L
Sbjct: 589 RHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKEL 646
Query: 374 VVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIP 433
V V +C LA AD K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y+E LRY+I
Sbjct: 647 HVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIE 706
Query: 434 ESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLP 493
+ +L + L S+WH F RN+FLGE E+ +++W D K + L + +P L
Sbjct: 707 KQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALE 766
Query: 494 S-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552
+ ++GE+ ++L+Y+P PV G + + GE+ +W+KE +L + G +SFVK
Sbjct: 767 AENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR-GSHLNSFVK 818
Query: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612
+LP ++ S++KT + KT NP +NHT VY+G R EDL C+ELTVWD L +N F
Sbjct: 819 CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQF 877
Query: 613 LGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661
LGG+R+G GTG S G VDWMDST EEV+LW+KM P +W E TL LR
Sbjct: 878 LGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 926
Score = 51.6 bits (122), Expect = 2e-06
Identities = 53/244 (21%), Positives = 101/244 (41%), Gaps = 17/244 (6%)
Query: 4 LLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTC 63
++DLSFL+EEE++ I+ VLQRD +++A+E+R+R L ++ + ++ G Y +
Sbjct: 1 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60
Query: 64 ARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYDQK 123
+ G + + + + + +E+ AKE + D F +
Sbjct: 61 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENG--------AKESWVNNVNKDAFLPPE 112
Query: 124 VNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLF 183
+ + S V+ +V T+ ++ P ++++K P F
Sbjct: 113 LAGVVEEPEEDAAPAS-PSSSVVNPASSVIDMSQENTRKPNVSP-----EKQRKNP---F 163
Query: 184 EVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQP 243
KL G S+ + ++E + TS+ D L +S S K + K+T P
Sbjct: 164 NSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLP 223
Query: 244 GGQN 247
G N
Sbjct: 224 GLSN 227
>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
Length = 934
Score = 298 bits (762), Expect = 1e-80
Identities = 169/409 (41%), Positives = 246/409 (60%), Gaps = 25/409 (6%)
Query: 267 RPSEYTKSVIDL-----RPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEEDI-DHLVKLH 320
+P E +S D+ +P++ L SKSVP D ++ E + + +L
Sbjct: 528 QPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLS 587
Query: 321 RQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSL 373
R K + SS+ + SS S + GS+MS+YS GDFGN+ V G I F+++Y + + L
Sbjct: 588 RHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKEL 645
Query: 374 VVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIP 433
V V +C LA AD K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y+E LRY+I
Sbjct: 646 HVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIE 705
Query: 434 ESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLP 493
+ +L + L S+WH F RN+FLGE E+ +++W D K + L + +P L
Sbjct: 706 KQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALE 765
Query: 494 S-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552
+ ++GE+ ++L+Y+P PV G + + GE+ +W+KE +L + G +SFVK
Sbjct: 766 AENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR-GSHLNSFVK 817
Query: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612
+LP ++ S++KT + KT NP +NHT VY+G R EDL C+ELTVWD L +N F
Sbjct: 818 CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQF 876
Query: 613 LGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661
LGG+R+G GTG S G VDWMDST EEV+LW+KM P +W E TL LR
Sbjct: 877 LGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 925
Score = 52.4 bits (124), Expect = 1e-06
Identities = 54/244 (22%), Positives = 100/244 (40%), Gaps = 18/244 (7%)
Query: 4 LLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTC 63
++DLSFL+EEE++ I+ VLQRD +++A+E+R+R L ++ + ++ G Y +
Sbjct: 1 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60
Query: 64 ARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYDQK 123
+ G + + + + + +E+ AKE + D F +
Sbjct: 61 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENG--------AKESWVNNVNKDAFLPPE 112
Query: 124 VNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLF 183
+ + S V+ +V T+ ++ P E++K P F
Sbjct: 113 LAGVVEEPEEDAAPAS-PSSSVVNPASSVIDMSQENTRKPNVSP------EKRKNP---F 162
Query: 184 EVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQP 243
KL G S+ + ++E + TS+ D L +S S K + K+T P
Sbjct: 163 NSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLP 222
Query: 244 GGQN 247
G N
Sbjct: 223 GLSN 226
>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
Length = 376
Score = 294 bits (752), Expect = 2e-79
Identities = 163/377 (43%), Positives = 234/377 (62%), Gaps = 20/377 (5%)
Query: 294 SKSVPGLNVDMEEEEEEEDI-DHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIY 345
SKSVP D ++ E + + +L R K + SS+ + SS S + GS+MS+Y
Sbjct: 2 SKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVY 61
Query: 346 SEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDK 405
S GDFGN+ V G I F+++Y + + L V V +C LA AD K+RS+PYVK YLLPDK
Sbjct: 62 S--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDK 119
Query: 406 SRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQM 465
+ GK+KT + + T+NP+Y+E LRY+I + +L + L S+WH F RN+FLGE E+ +
Sbjct: 120 GKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDL 179
Query: 466 DSWKLDKKLDHCLPLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGE 524
++W D K + L + +P L + ++GE+ ++L+Y+P PV G + +
Sbjct: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT--- 233
Query: 525 GGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVY 584
GE+ +W+KE +L + G +SFVK +LP ++ S++KT + KT NP +NHT VY
Sbjct: 234 -GEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 291
Query: 585 NGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQ 644
+G R EDL C+ELTVWD L +N FLGG+R+G GTG S G VDWMDST EEV+LW+
Sbjct: 292 DGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWE 350
Query: 645 KMRQYPGSWAEGTLQLR 661
KM P +W E TL LR
Sbjct: 351 KMVNSPNTWIEATLPLR 367
>gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens]
Length = 376
Score = 294 bits (752), Expect = 2e-79
Identities = 163/377 (43%), Positives = 234/377 (62%), Gaps = 20/377 (5%)
Query: 294 SKSVPGLNVDMEEEEEEEDI-DHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIY 345
SKSVP D ++ E + + +L R K + SS+ + SS S + GS+MS+Y
Sbjct: 2 SKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVY 61
Query: 346 SEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDK 405
S GDFGN+ V G I F+++Y + + L V V +C LA AD K+RS+PYVK YLLPDK
Sbjct: 62 S--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDK 119
Query: 406 SRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQM 465
+ GK+KT + + T+NP+Y+E LRY+I + +L + L S+WH F RN+FLGE E+ +
Sbjct: 120 GKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDL 179
Query: 466 DSWKLDKKLDHCLPLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGE 524
++W D K + L + +P L + ++GE+ ++L+Y+P PV G + +
Sbjct: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT--- 233
Query: 525 GGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVY 584
GE+ +W+KE +L + G +SFVK +LP ++ S++KT + KT NP +NHT VY
Sbjct: 234 -GEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 291
Query: 585 NGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQ 644
+G R EDL C+ELTVWD L +N FLGG+R+G GTG S G VDWMDST EEV+LW+
Sbjct: 292 DGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWE 350
Query: 645 KMRQYPGSWAEGTLQLR 661
KM P +W E TL LR
Sbjct: 351 KMVNSPNTWIEATLPLR 367
>gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens]
Length = 365
Score = 289 bits (739), Expect = 7e-78
Identities = 155/364 (42%), Positives = 227/364 (62%), Gaps = 16/364 (4%)
Query: 303 DMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTI----GSMMSIYSEAGDFGNIFVTG 358
D E + E L + + + +++ S S M+++ GS+MS+YS GDFGN+ V G
Sbjct: 4 DRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKG 61
Query: 359 RIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRD 418
I F+++Y + + L V V +C LA AD K+RS+PYVK YLLPDK + GK+KT + +
Sbjct: 62 NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121
Query: 419 TINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCL 478
T+NP+Y+E LRY+I + +L + L S+WH F RN+FLGE E+ +++W D K + L
Sbjct: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181
Query: 479 PLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
+ +P L + ++GE+ ++L+Y+P PV G + + GE+ +W+KE +
Sbjct: 182 RWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLD 234
Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
L + G +SFVK +LP ++ S++KT + KT NP +NHT VY+G R EDL C+
Sbjct: 235 LPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 293
Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGT 657
ELTVWD L +N FLGG+R+G GTG S G VDWMDST EEV+LW+KM P +W E T
Sbjct: 294 ELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEAT 352
Query: 658 LQLR 661
L LR
Sbjct: 353 LPLR 356
>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
Length = 910
Score = 285 bits (729), Expect = 1e-76
Identities = 153/345 (44%), Positives = 217/345 (62%), Gaps = 14/345 (4%)
Query: 320 HRQKLARSSMQSGSSMS--TIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHV 377
H KL R S + + GS+MS+YS GDFGN+ V G I F+++Y + + L V V
Sbjct: 568 HPDKLKRMSKSVPAFLQDEVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFV 625
Query: 378 KECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLL 437
+C LA AD K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y+E LRY+I + +L
Sbjct: 626 AQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQIL 685
Query: 438 AQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPS-HK 496
+ L S+WH F RN+FLGE E+ +++W D K + L + +P L + ++
Sbjct: 686 KTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENR 745
Query: 497 GELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLL 556
GE+ ++L+Y+P PV G + + GE+ +W+KE +L + G +SFVK +L
Sbjct: 746 GEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR-GSHLNSFVKCTIL 797
Query: 557 PMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGV 616
P ++ S++KT + KT NP +NHT VY+G R EDL C+ELTVWD L +N FLGG+
Sbjct: 798 PDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGL 856
Query: 617 RLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661
R+G GTG S G VDWMDST EEV+LW+KM P +W E TL LR
Sbjct: 857 RIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 901
Score = 52.4 bits (124), Expect = 1e-06
Identities = 54/244 (22%), Positives = 100/244 (40%), Gaps = 18/244 (7%)
Query: 4 LLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTC 63
++DLSFL+EEE++ I+ VLQRD +++A+E+R+R L ++ + ++ G Y +
Sbjct: 1 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60
Query: 64 ARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYDQK 123
+ G + + + + + +E+ AKE + D F +
Sbjct: 61 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENG--------AKESWVNNVNKDAFLPPE 112
Query: 124 VNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLF 183
+ + S V+ +V T+ ++ P E++K P F
Sbjct: 113 LAGVVEEPEEDAAPAS-PSSSVVNPASSVIDMSQENTRKPNVSP------EKRKNP---F 162
Query: 184 EVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQP 243
KL G S+ + ++E + TS+ D L +S S K + K+T P
Sbjct: 163 NSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLP 222
Query: 244 GGQN 247
G N
Sbjct: 223 GLSN 226
>gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens]
Length = 336
Score = 284 bits (726), Expect = 2e-76
Identities = 148/324 (45%), Positives = 210/324 (64%), Gaps = 12/324 (3%)
Query: 339 GSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVK 398
GS+MS+YS GDFGN+ V G I F+++Y + + L V V +C LA AD K+RS+PYVK
Sbjct: 15 GSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 72
Query: 399 TYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFL 458
YLLPDK + GK+KT + + T+NP+Y+E LRY+I + +L + L S+WH F RN+FL
Sbjct: 73 AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 132
Query: 459 GEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDR 517
GE E+ +++W D K + L + +P L + ++GE+ ++L+Y+P PV G +
Sbjct: 133 GEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKK 189
Query: 518 KKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPH 577
+ GE+ +W+KE +L + G +SFVK +LP ++ S++KT + KT NP
Sbjct: 190 LPTT----GEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPI 244
Query: 578 YNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTG 637
+NHT VY+G R EDL C+ELTVWD L +N FLGG+R+G GTG S G VDWMDST
Sbjct: 245 FNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTS 303
Query: 638 EEVSLWQKMRQYPGSWAEGTLQLR 661
EEV+LW+KM P +W E TL LR
Sbjct: 304 EEVALWEKMVNSPNTWIEATLPLR 327
>gi|14249614 synaptotagmin-like 1 [Homo sapiens]
Length = 550
Score = 263 bits (671), Expect = 5e-70
Identities = 188/558 (33%), Positives = 286/558 (51%), Gaps = 87/558 (15%)
Query: 110 ELKKATGDWFYDQKVNRFAY-RTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPG 168
+LK TGDWF + + R GS+++R S+R K ++ GD PG
Sbjct: 75 QLKILTGDWFQEARSQRHHNAHFGSDLVRASMRRK---------------KSTRGDQAPG 119
Query: 169 RKIIQERQKEPSVLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWK 228
+R+ E +V + + + EA E L T SD + + G +
Sbjct: 120 H----DREAEAAVKEKEEGPEPRLTIDEAPQERLRE-TEASDPEEASQAQEDPGQGDQ-- 172
Query: 229 KMSAPKSQVEKETQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESG 288
++ A ++ E E GG+ + RP+ ++
Sbjct: 173 QVCAEEADPELEPASGGEQ-----------------------------EPRPQQAQTKAA 203
Query: 289 S-LGDRSKSVPGLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSE 347
S + + + PG + ++ R + SS+ S +S + GS MS+
Sbjct: 204 SQILENGEEAPGPDPSLD---------------RMLSSSSSVSSLNSSTLSGSQMSL--- 245
Query: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407
+GD + V G + F+L YE L VHV +C LA A ++RS+PYVK+YLLPDK
Sbjct: 246 SGDAEAVQVRGSVHFALHYEPGAAELRVHVIQCQGLAAA--RRRRSDPYVKSYLLPDK-- 301
Query: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
Q KRKT++K+ +NP+++ETLRY +P++ L R L SVWH GRN FLGE E+ +D+
Sbjct: 302 QSKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVWHRESLGRNIFLGEVEVPLDT 361
Query: 468 WKLDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGE 527
W + LPL ++ SP LPS +G L +SLKY+PA G GE
Sbjct: 362 WDWGSE-PTWLPLQPRV-PPSPDDLPS-RGLLALSLKYVPAGSEGAGLP-------PSGE 411
Query: 528 LQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGV 587
L W+KEA++L +A G+ D++V+ ++LP ++AS+++T V++++L+P +NHT VY+G
Sbjct: 412 LHFWVKEARDLLPLRA-GSLDTYVQCFVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGF 470
Query: 588 RLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMR 647
DL+ C EL++WD LA N LGG RL +GTG S G V WMDST EE LWQ +
Sbjct: 471 GPADLRQACAELSLWDHGALA-NRQLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQALL 529
Query: 648 QYPGSWAEGTLQLRSSMA 665
+ P W +G L LR+++A
Sbjct: 530 EQPCEWVDGLLPLRTNLA 547
Score = 43.9 bits (102), Expect = 5e-04
Identities = 20/37 (54%), Positives = 29/37 (78%)
Query: 4 LLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLK 40
LLDLSFL+EEE++ I VLQRD +R+ +E R+ +L+
Sbjct: 31 LLDLSFLTEEEQEAIAGVLQRDARLRQLEEGRVSKLR 67
>gi|110227631 synaptotagmin-like 3 [Homo sapiens]
Length = 542
Score = 213 bits (543), Expect = 4e-55
Identities = 141/389 (36%), Positives = 203/389 (52%), Gaps = 40/389 (10%)
Query: 293 RSKSVPGLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIY 345
R S P + + +E+ + + ++K + ++ S + STI GS++SI
Sbjct: 172 RKVSAPDILKPLNQEDPKCSTNPILK-------QQNLPSSPAPSTIFSGGFRHGSLISID 224
Query: 346 S---EAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLL 402
S E G+F N VTG I F++ Y +T SL + +K C LAY +E KK+ NPYVKTYLL
Sbjct: 225 STCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLL 284
Query: 403 PDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAE 462
PD+S QGKRKT ++R+T++P + ETL+Y++ + L R LQ SVWH G R FLGE
Sbjct: 285 PDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVI 344
Query: 463 IQMDSWKLDKKLDHCL---PLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKK 519
I + +W + PL K + + +P GEL V K + S+ RK
Sbjct: 345 IPLATWDFEDSTTQSFRWHPLRAK-AEKYEDSVPQSNGELTVRAKLVLPSR-----PRKL 398
Query: 520 SKGGEG-------GELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKK 572
+ EG G+L + + AKNL + GT +SFVKG L + + K+PV++K
Sbjct: 399 QEAQEGTDQPSLHGQLCLVVLGAKNL-PVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRK 457
Query: 573 TLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASND-FLGGVRLGVGTGISNGEVVD 631
P + H+FV++GV L+ LELTVWD+ ND LGG RLG S G+
Sbjct: 458 QACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLG-----SKGDTAV 512
Query: 632 WMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660
D+ WQK+ P W + TL L
Sbjct: 513 GGDACSLSKLQWQKVLSSPNLWTDMTLVL 541
Score = 119 bits (299), Expect = 7e-27
Identities = 61/162 (37%), Positives = 89/162 (54%), Gaps = 17/162 (10%)
Query: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60
M++ +DLS L E E++ IL VL RD+ V+ +E+R R+LK L ++ KGAK + +
Sbjct: 1 MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKE 60
Query: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRI-QESNGTWRCKVCAKEIELKKATGDWF 119
+ CARCQ+ LG L + CRGC+H VC CR+ W+C VC ++ +K TG+WF
Sbjct: 61 KCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWF 120
Query: 120 YDQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQ 161
Y+++ +F P K ETVG LL Q
Sbjct: 121 YEERAKKF----------------PTGGKHETVGGQLLQSYQ 146
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 173 bits (438), Expect = 5e-43
Identities = 170/668 (25%), Positives = 275/668 (41%), Gaps = 116/668 (17%)
Query: 10 LSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQES 69
L++EEK++I V+ R E++ + +++RI RL + L +++ A G C C E
Sbjct: 50 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNR-----CILCGEQ 104
Query: 70 LGRLSPKTNTCRGCNHLVCRDCRIQESN---GTWRCKVCAKEIELKKATGDWFY------ 120
LG L C C VC C ++ +N W CK+C ++ E+ K +G WF+
Sbjct: 105 LGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQ 164
Query: 121 --DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKE 178
Q + + + + +PA + ++ PG+K +
Sbjct: 165 VLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSE-DRRGPGQKTGPDPASA 223
Query: 179 PSVLFEVPKLKSGK----SALEAESESLDSFTADSDST------SRRDSLDKSGLFPEWK 228
P P ++ S+ +SES D DS+ R +S+ S P
Sbjct: 224 PGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSV 283
Query: 229 KMSAPKSQVEKETQPGGQNV------VFVDEGEMIFKKNTRKILRPSEYTKS------VI 276
+ AP + T PGG F D+ + + P E +
Sbjct: 284 QSPAPPQPGQPGT-PGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAV 342
Query: 277 DLRPEDVVHESGSLGDRSKSVP----GLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSG 332
R + + H SG S + P EEEEEE ++
Sbjct: 343 GAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEE---------------ANSYDS 387
Query: 333 SSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKR 392
+T+G+ + FSL Y+Q SL + + L D +
Sbjct: 388 DEATTLGA-------------------LEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGL 427
Query: 393 SNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYE-IPESLLAQRTLQFSVWHHGR 451
++PYVK +LLP S+ K +T R+T NP+++ETL Y I + + ++TL+ SV +
Sbjct: 428 ADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDK 487
Query: 452 FGRNTFLGEAEIQMDSWKLDKK------LDHCLPLHGKISAESPTGLP------------ 493
FG N F+GE + K +++ L+ +P+ + S G+
Sbjct: 488 FGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGD 547
Query: 494 -SHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552
+G+++VSL Y T GG L V I +L A A G SD FVK
Sbjct: 548 IEERGKILVSLMY----STQQGG------------LIVGIIRCVHLAAMDANGYSDPFVK 591
Query: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612
+L P K +K KT + KKTLNP +N F Y+ ++ DL L+++VWD + SND+
Sbjct: 592 LWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGKSNDY 650
Query: 613 LGGVRLGV 620
+GG +LG+
Sbjct: 651 IGGCQLGI 658
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 173 bits (438), Expect = 5e-43
Identities = 170/668 (25%), Positives = 275/668 (41%), Gaps = 116/668 (17%)
Query: 10 LSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQES 69
L++EEK++I V+ R E++ + +++RI RL + L +++ A G C C E
Sbjct: 46 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNR-----CILCGEQ 100
Query: 70 LGRLSPKTNTCRGCNHLVCRDCRIQESN---GTWRCKVCAKEIELKKATGDWFY------ 120
LG L C C VC C ++ +N W CK+C ++ E+ K +G WF+
Sbjct: 101 LGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQ 160
Query: 121 --DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKE 178
Q + + + + +PA + ++ PG+K +
Sbjct: 161 VLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSE-DRRGPGQKTGPDPASA 219
Query: 179 PSVLFEVPKLKSGK----SALEAESESLDSFTADSDST------SRRDSLDKSGLFPEWK 228
P P ++ S+ +SES D DS+ R +S+ S P
Sbjct: 220 PGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSV 279
Query: 229 KMSAPKSQVEKETQPGGQNV------VFVDEGEMIFKKNTRKILRPSEYTKS------VI 276
+ AP + T PGG F D+ + + P E +
Sbjct: 280 QSPAPPQPGQPGT-PGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAV 338
Query: 277 DLRPEDVVHESGSLGDRSKSVP----GLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSG 332
R + + H SG S + P EEEEEE ++
Sbjct: 339 GAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEE---------------ANSYDS 383
Query: 333 SSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKR 392
+T+G+ + FSL Y+Q SL + + L D +
Sbjct: 384 DEATTLGA-------------------LEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGL 423
Query: 393 SNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYE-IPESLLAQRTLQFSVWHHGR 451
++PYVK +LLP S+ K +T R+T NP+++ETL Y I + + ++TL+ SV +
Sbjct: 424 ADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDK 483
Query: 452 FGRNTFLGEAEIQMDSWKLDKK------LDHCLPLHGKISAESPTGLP------------ 493
FG N F+GE + K +++ L+ +P+ + S G+
Sbjct: 484 FGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGD 543
Query: 494 -SHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552
+G+++VSL Y T GG L V I +L A A G SD FVK
Sbjct: 544 IEERGKILVSLMY----STQQGG------------LIVGIIRCVHLAAMDANGYSDPFVK 587
Query: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612
+L P K +K KT + KKTLNP +N F Y+ ++ DL L+++VWD + SND+
Sbjct: 588 LWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGKSNDY 646
Query: 613 LGGVRLGV 620
+GG +LG+
Sbjct: 647 IGGCQLGI 654
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 146 bits (368), Expect = 7e-35
Identities = 89/277 (32%), Positives = 147/277 (53%), Gaps = 27/277 (9%)
Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
G++ FSL Y+ Q L V V + +L D S+PYVK +LLPDK + K +T + R
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197
Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
T+NP ++ET +++P L +TL +++ RF ++ +GE ++ M++ L + ++
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257
Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
L G E P G++ SL+Y+P + G+L V I EAKN
Sbjct: 258 RDLQGGEKEE-----PEKLGDICTSLRYVPTA----------------GKLTVCILEAKN 296
Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
L GG SD +VK +L+ + K+KT V KKTLNP++N +F + + E +Q + +
Sbjct: 297 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQV 355
Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMD 634
+TV D + L N+ +G ++ VG+ + E+ W D
Sbjct: 356 VVTVLDYDKLGKNEAIG--KIFVGSNATGTELRHWSD 390
Score = 68.6 bits (166), Expect = 2e-11
Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 3/116 (2%)
Query: 524 EGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFV 583
+ +L V + +A L A GGTSD +VK +LLP +K K +T V +KTLNP +N TF
Sbjct: 152 QANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP--DKKKKYETKVHRKTLNPAFNETFT 209
Query: 584 YNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEE 639
+ V ++L L + ++D + + +D +G V++ + T + +W D G E
Sbjct: 210 FK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 264
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 146 bits (368), Expect = 7e-35
Identities = 89/277 (32%), Positives = 147/277 (53%), Gaps = 27/277 (9%)
Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
G++ FSL Y+ Q L V V + +L D S+PYVK +LLPDK + K +T + R
Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197
Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
T+NP ++ET +++P L +TL +++ RF ++ +GE ++ M++ L + ++
Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257
Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
L G E P G++ SL+Y+P + G+L V I EAKN
Sbjct: 258 RDLQGGEKEE-----PEKLGDICTSLRYVPTA----------------GKLTVCILEAKN 296
Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
L GG SD +VK +L+ + K+KT V KKTLNP++N +F + + E +Q + +
Sbjct: 297 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQV 355
Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMD 634
+TV D + L N+ +G ++ VG+ + E+ W D
Sbjct: 356 VVTVLDYDKLGKNEAIG--KIFVGSNATGTELRHWSD 390
Score = 68.6 bits (166), Expect = 2e-11
Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 3/116 (2%)
Query: 524 EGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFV 583
+ +L V + +A L A GGTSD +VK +LLP +K K +T V +KTLNP +N TF
Sbjct: 152 QANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP--DKKKKYETKVHRKTLNPAFNETFT 209
Query: 584 YNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEE 639
+ V ++L L + ++D + + +D +G V++ + T + +W D G E
Sbjct: 210 FK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 264
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 143 bits (360), Expect = 6e-34
Identities = 94/291 (32%), Positives = 145/291 (49%), Gaps = 26/291 (8%)
Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
GR+ +SL Y+ Q+ L+V + + LA D S+PYV+ YLLPDK R + +T + R
Sbjct: 110 GRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGS-SDPYVRVYLLPDKRR--RYETKVHR 166
Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
T+NP + ET +++P L R L +V+ RF RN +GE + M S L + +
Sbjct: 167 QTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAW 226
Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
L +P G++ SL+Y+P + G+L V + EAKN
Sbjct: 227 RELQA-----APREEQEKLGDICFSLRYVPTA----------------GKLTVIVLEAKN 265
Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
L GG SD +VK +LL K K+KT + K TLNP+YN F + V + +Q + +
Sbjct: 266 LKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE-VPCDQVQKVQV 324
Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISN-GEVVDWMDSTGEEVSLWQKMR 647
ELTV D + L N+ +G V +G G + D + + ++ W +R
Sbjct: 325 ELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLR 375
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 139 bits (349), Expect = 1e-32
Identities = 102/316 (32%), Positives = 152/316 (48%), Gaps = 22/316 (6%)
Query: 308 EEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYE 367
E++ED+D L + S S + ++ + + G + FSL Y+
Sbjct: 78 EDDEDVDQLFGAYGSSPGPSPGPSPARPPAKPPEDEPDADGYESDDCTALGTLDFSLLYD 137
Query: 368 QQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDET 427
Q+ +L + + L D ++PYVK +LLP S+ K +T R+T+NP ++ET
Sbjct: 138 QENNALHCTITKAKGLKPMDH-NGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNET 196
Query: 428 LRYE-IPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLD--KKLDHCLPLHGKI 484
L Y I + + ++TL+ SV +F N F+GE + + K + K + CL +
Sbjct: 197 LTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFNICLEKQLPV 256
Query: 485 SAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAG 544
L +G +++SLKY K G L V I +L A A
Sbjct: 257 DKTEDKSL-EERGRILISLKY------------SSQKQG----LLVGIVRCAHLAAMDAN 299
Query: 545 GTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDR 604
G SD +VK YL P +K SK KT V KKTLNP +N F Y ++ DL LE+TVWD
Sbjct: 300 GYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYE-IKHGDLAKKSLEVTVWDY 358
Query: 605 EPLASNDFLGGVRLGV 620
+ SNDF+GGV LG+
Sbjct: 359 DIGKSNDFIGGVVLGI 374
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 135 bits (339), Expect = 2e-31
Identities = 89/293 (30%), Positives = 145/293 (49%), Gaps = 38/293 (12%)
Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
G++ +SL Y+ Q L+V + + +L D S+PYVK +LLPDK + K +T + R
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETKVHR 200
Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
T+NP+++E +++P S L +TL +V+ RF ++ +GE ++ M++ +
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
L E G++ SL+Y+P + G+L V I EAKN
Sbjct: 261 RDLQSAEKEEQ-----EKLGDICFSLRYVPTA----------------GKLTVVILEAKN 299
Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
L GG SD +VK +L+ + K+KT + K TLNP+YN +F + V E +Q + +
Sbjct: 300 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQV 358
Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650
+TV D + + ND +G V +G +STG E+ W M P
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSDMLANP 398
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 135 bits (339), Expect = 2e-31
Identities = 89/293 (30%), Positives = 145/293 (49%), Gaps = 38/293 (12%)
Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
G++ +SL Y+ Q L+V + + +L D S+PYVK +LLPDK + K +T + R
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETKVHR 200
Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
T+NP+++E +++P S L +TL +V+ RF ++ +GE ++ M++ +
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
L E G++ SL+Y+P + G+L V I EAKN
Sbjct: 261 RDLQSAEKEEQ-----EKLGDICFSLRYVPTA----------------GKLTVVILEAKN 299
Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
L GG SD +VK +L+ + K+KT + K TLNP+YN +F + V E +Q + +
Sbjct: 300 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQV 358
Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650
+TV D + + ND +G V +G +STG E+ W M P
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSDMLANP 398
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 135 bits (339), Expect = 2e-31
Identities = 89/293 (30%), Positives = 145/293 (49%), Gaps = 38/293 (12%)
Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
G++ +SL Y+ Q L+V + + +L D S+PYVK +LLPDK + K +T + R
Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETKVHR 200
Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477
T+NP+++E +++P S L +TL +V+ RF ++ +GE ++ M++ +
Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260
Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537
L E G++ SL+Y+P + G+L V I EAKN
Sbjct: 261 RDLQSAEKEEQ-----EKLGDICFSLRYVPTA----------------GKLTVVILEAKN 299
Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597
L GG SD +VK +L+ + K+KT + K TLNP+YN +F + V E +Q + +
Sbjct: 300 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQV 358
Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650
+TV D + + ND +G V +G +STG E+ W M P
Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSDMLANP 398
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 131 bits (330), Expect = 2e-30
Identities = 96/300 (32%), Positives = 149/300 (49%), Gaps = 44/300 (14%)
Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
GRI FS+ Y Q +L V + + +L A + S+P+VK YLLPDK K +T +KR
Sbjct: 137 GRIQFSVGYNFQESTLTVKIMKAQELP-AKDFSGTSDPFVKIYLLPDKKH--KLETKVKR 193
Query: 418 DTINPLYDETLRYE-IPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLD----- 471
+NP ++ET +E P + QR L V + RF RN +GE I ++ L
Sbjct: 194 KNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTF 253
Query: 472 -KKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQV 530
K L C G +GEL++SL Y P++ + + V
Sbjct: 254 WKDLKPCSDGSGS------------RGELLLSLCYNPSANSII----------------V 285
Query: 531 WIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLE 590
I +A+NL A GGTSD +VK +L+ + K+KT MK+ LNP +N +F ++ + E
Sbjct: 286 NIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFD-IPTE 344
Query: 591 DLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTG---EEVSLWQKMR 647
L+ + +TV D++ L+ ND +G + L +G GEV W D + V+ W +++
Sbjct: 345 KLRETTIIITVMDKDKLSRNDVIGKIYLSWKSG--PGEVKHWKDMIARPRQPVAQWHQLK 402
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 130 bits (326), Expect = 5e-30
Identities = 94/284 (33%), Positives = 142/284 (50%), Gaps = 48/284 (16%)
Query: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407
+G+ G GRI+F+L+Y + LVV + + L A ++ S+PYVK YLLPD+ +
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK 349
Query: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
K +T + R T+NP+++ET ++ +P + LAQR L FSV+ RF R+ +G+
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV------ 401
Query: 468 WKLDKKLDHCLPLHGKISAESPTGLP------------SHKGELVVSLKYIPASKTPVGG 515
LD+ L L AE P P + GEL SL Y+P +
Sbjct: 402 -----VLDNLLEL-----AEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTA------ 445
Query: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575
G L V I +A NL A G SD +VK L+ + KRKT + K TLN
Sbjct: 446 ----------GRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLN 495
Query: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619
P YN V++ V E ++++ L + V D + + N+ +G R+G
Sbjct: 496 PTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
Score = 55.8 bits (133), Expect = 1e-07
Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
G + FSL Y L V + + L D S+PYVK L+ + R KRKTSIK+
Sbjct: 433 GELNFSLCYLPTAGRLTVTIIKASNLKAMD-LTGFSDPYVKASLISEGRRLKKRKTSIKK 491
Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
+T+NP Y+E L +++ + L +V + G N +G + D+
Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 130 bits (326), Expect = 5e-30
Identities = 94/284 (33%), Positives = 142/284 (50%), Gaps = 48/284 (16%)
Query: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407
+G+ G GRI+F+L+Y + LVV + + L A ++ S+PYVK YLLPD+ +
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK 349
Query: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
K +T + R T+NP+++ET ++ +P + LAQR L FSV+ RF R+ +G+
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV------ 401
Query: 468 WKLDKKLDHCLPLHGKISAESPTGLP------------SHKGELVVSLKYIPASKTPVGG 515
LD+ L L AE P P + GEL SL Y+P +
Sbjct: 402 -----VLDNLLEL-----AEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTA------ 445
Query: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575
G L V I +A NL A G SD +VK L+ + KRKT + K TLN
Sbjct: 446 ----------GRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLN 495
Query: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619
P YN V++ V E ++++ L + V D + + N+ +G R+G
Sbjct: 496 PTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
Score = 55.8 bits (133), Expect = 1e-07
Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
G + FSL Y L V + + L D S+PYVK L+ + R KRKTSIK+
Sbjct: 433 GELNFSLCYLPTAGRLTVTIIKASNLKAMD-LTGFSDPYVKASLISEGRRLKKRKTSIKK 491
Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
+T+NP Y+E L +++ + L +V + G N +G + D+
Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 130 bits (326), Expect = 5e-30
Identities = 94/284 (33%), Positives = 142/284 (50%), Gaps = 48/284 (16%)
Query: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407
+G+ G GRI+F+L+Y + LVV + + L A ++ S+PYVK YLLPD+ +
Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK 349
Query: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
K +T + R T+NP+++ET ++ +P + LAQR L FSV+ RF R+ +G+
Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV------ 401
Query: 468 WKLDKKLDHCLPLHGKISAESPTGLP------------SHKGELVVSLKYIPASKTPVGG 515
LD+ L L AE P P + GEL SL Y+P +
Sbjct: 402 -----VLDNLLEL-----AEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTA------ 445
Query: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575
G L V I +A NL A G SD +VK L+ + KRKT + K TLN
Sbjct: 446 ----------GRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLN 495
Query: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619
P YN V++ V E ++++ L + V D + + N+ +G R+G
Sbjct: 496 PTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538
Score = 55.8 bits (133), Expect = 1e-07
Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
G + FSL Y L V + + L D S+PYVK L+ + R KRKTSIK+
Sbjct: 433 GELNFSLCYLPTAGRLTVTIIKASNLKAMD-LTGFSDPYVKASLISEGRRLKKRKTSIKK 491
Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467
+T+NP Y+E L +++ + L +V + G N +G + D+
Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 125 bits (314), Expect = 1e-28
Identities = 89/331 (26%), Positives = 162/331 (48%), Gaps = 32/331 (9%)
Query: 329 MQSGSSMSTIGSMM-------SIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECH 381
+Q G + ++IG + S+ SE ++ + G++ F+L+Y+ + + LVV + +
Sbjct: 197 LQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKAL 256
Query: 382 QLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRT 441
L A + S+PYVK YLLPD+ + K +T + R T+NPL+DET ++ + L+ R
Sbjct: 257 DLP-AKDFTGTSDPYVKMYLLPDRKK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRK 313
Query: 442 LQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPSHKGELVV 501
L FSV+ RF R+ +G E+ +D+ L + I + + GE++
Sbjct: 314 LHFSVYDFDRFSRHDMIG--EVILDNLFEVSDLSREATVWKDIHCATTESI--DLGEIMF 369
Query: 502 SLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNK 561
SL Y+P + G + + + + +NL A G+SD +VK L+ +
Sbjct: 370 SLCYLPTA----------------GRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRR 413
Query: 562 ASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGV- 620
KRKT K TLNP YN +++ + E++ + L + V D + + N+ +G R G+
Sbjct: 414 LKKRKTTTKKNTLNPVYNEAIIFD-IPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLD 472
Query: 621 GTGISNGEVVDWMDSTGEEVSLWQKMRQYPG 651
G+ + + + ++ W + + PG
Sbjct: 473 AEGLGRDHWNEMLAYHRKPITHWHPLLELPG 503
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,983,415
Number of Sequences: 37866
Number of extensions: 1233245
Number of successful extensions: 4990
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 95
Number of HSP's successfully gapped in prelim test: 114
Number of HSP's that attempted gapping in prelim test: 4296
Number of HSP's gapped (non-prelim): 515
length of query: 671
length of database: 18,247,518
effective HSP length: 109
effective length of query: 562
effective length of database: 14,120,124
effective search space: 7935509688
effective search space used: 7935509688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.