BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|193804860 synaptotagmin-like 4 [Homo sapiens] (671 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|193804862 synaptotagmin-like 4 [Homo sapiens] 1351 0.0 gi|193804860 synaptotagmin-like 4 [Homo sapiens] 1351 0.0 gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] 496 e-140 gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens] 496 e-140 gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] 489 e-138 gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens] 301 1e-81 gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens] 298 8e-81 gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] 298 1e-80 gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] 298 1e-80 gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens] 294 2e-79 gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens] 294 2e-79 gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens] 289 7e-78 gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] 285 1e-76 gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens] 284 2e-76 gi|14249614 synaptotagmin-like 1 [Homo sapiens] 263 5e-70 gi|110227631 synaptotagmin-like 3 [Homo sapiens] 213 4e-55 gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 173 5e-43 gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 173 5e-43 gi|211059429 synaptotagmin II [Homo sapiens] 146 7e-35 gi|31543670 synaptotagmin II [Homo sapiens] 146 7e-35 gi|92859638 synaptotagmin V [Homo sapiens] 143 6e-34 gi|6005997 double C2-like domains, beta [Homo sapiens] 139 1e-32 gi|209447073 synaptotagmin I [Homo sapiens] 135 2e-31 gi|5032139 synaptotagmin I [Homo sapiens] 135 2e-31 gi|209447070 synaptotagmin I [Homo sapiens] 135 2e-31 gi|38570146 synaptotagmin VII [Homo sapiens] 131 2e-30 gi|238550198 synaptotagmin III [Homo sapiens] 130 5e-30 gi|238550196 synaptotagmin III [Homo sapiens] 130 5e-30 gi|14150054 synaptotagmin III [Homo sapiens] 130 5e-30 gi|39752671 synaptotagmin X [Homo sapiens] 125 1e-28 >gi|193804862 synaptotagmin-like 4 [Homo sapiens] Length = 671 Score = 1351 bits (3496), Expect = 0.0 Identities = 671/671 (100%), Positives = 671/671 (100%) Query: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD Sbjct: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60 Query: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 120 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY Sbjct: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 120 Query: 121 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 180 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS Sbjct: 121 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 180 Query: 181 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 240 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE Sbjct: 181 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 240 Query: 241 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 300 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL Sbjct: 241 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 300 Query: 301 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 360 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI Sbjct: 301 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 360 Query: 361 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 420 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI Sbjct: 361 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 420 Query: 421 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 480 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL Sbjct: 421 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 480 Query: 481 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 540 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA Sbjct: 481 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 540 Query: 541 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 600 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT Sbjct: 541 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 600 Query: 601 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL Sbjct: 601 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660 Query: 661 RSSMAKQKLGL 671 RSSMAKQKLGL Sbjct: 661 RSSMAKQKLGL 671 >gi|193804860 synaptotagmin-like 4 [Homo sapiens] Length = 671 Score = 1351 bits (3496), Expect = 0.0 Identities = 671/671 (100%), Positives = 671/671 (100%) Query: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD Sbjct: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60 Query: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 120 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY Sbjct: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFY 120 Query: 121 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 180 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS Sbjct: 121 DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPS 180 Query: 181 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 240 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE Sbjct: 181 VLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKE 240 Query: 241 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 300 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL Sbjct: 241 TQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGL 300 Query: 301 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 360 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI Sbjct: 301 NVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRI 360 Query: 361 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 420 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI Sbjct: 361 AFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTI 420 Query: 421 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 480 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL Sbjct: 421 NPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPL 480 Query: 481 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 540 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA Sbjct: 481 HGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTA 540 Query: 541 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 600 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT Sbjct: 541 AKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELT 600 Query: 601 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL Sbjct: 601 VWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660 Query: 661 RSSMAKQKLGL 671 RSSMAKQKLGL Sbjct: 661 RSSMAKQKLGL 671 >gi|254039650 synaptotagmin-like 5 isoform 1 [Homo sapiens] Length = 730 Score = 496 bits (1277), Expect = e-140 Identities = 296/732 (40%), Positives = 420/732 (57%), Gaps = 70/732 (9%) Query: 2 SELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDR 61 SE ++LSFL + EK++IL VL+RDE ++K ++KRIR+LKNELLE KR+ K +Q + R Sbjct: 5 SEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGK--TQQEASR 62 Query: 62 TCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYD 121 C C +LG + + + C+ C+ VCR+CR+ NG+W+C VC K +L+ TG+WF++ Sbjct: 63 VCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122 Query: 122 QKVNRFAYRT--GSEIIRMS-LRHKPAVSKRETVGQSLLHQTQMGDIWP--GRKIIQERQ 176 +K RF G++++R S LR P + ++ Q+ + D P G+K + Sbjct: 123 EKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQT-RQDAEKSDTSPVAGKKASHDGP 181 Query: 177 KEPSVLFE-----------VPKLKSGKS-ALEAESESLDSFT----ADSDSTSRRDSLDK 220 K L PK +G+S +L+ + + S +D ST D D+ Sbjct: 182 KRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQ 241 Query: 221 ------------SGLFPEWKKMSAPKSQVEKET---QPGGQNVVFVDEGEMIFKKNTRKI 265 +G+ P + AP ++ + G +N + + E ++ T+ Sbjct: 242 EPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSH 301 Query: 266 LR---------------PSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEE 310 R S+ ++S +DL ++ RSKSVPG EE E Sbjct: 302 RRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETE 361 Query: 311 EDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQT 370 E ID LV + + SG S +++ SMMS+YSE GD+GN+ V+G I + Y +T Sbjct: 362 ESIDALVS-SQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT 420 Query: 371 QSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRY 430 L + VK C LA DE K+R++ YVK+YLLPDKSR KRKT I+ T NP ++ETL+Y Sbjct: 421 GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKY 479 Query: 431 EIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPT 490 I + L RTLQ SVWH+ RFGRN+FLGE EI DSW + D L K+ Sbjct: 480 TISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDI 539 Query: 491 GLPSHKGELVVSLKYIP-------------ASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 GL +KGEL V L+YIP +KT G +K+S GG L+V+IKEAKN Sbjct: 540 GL-QYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKN 598 Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 LTA K+GGTSDSFVKGYLLP +KA+K KT V+KK++NP +NHTF+++G+ +D++++CL Sbjct: 599 LTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCL 658 Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGT 657 ELT+WD+E +SN FLGGVRL G+G+S+G+ VDWMDS GEE LWQKM PG+ EG Sbjct: 659 ELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGV 718 Query: 658 LQLRSSMAKQKL 669 L LRSSM K +L Sbjct: 719 LMLRSSMGKCRL 730 >gi|20270305 synaptotagmin-like 5 isoform 1 [Homo sapiens] Length = 730 Score = 496 bits (1277), Expect = e-140 Identities = 296/732 (40%), Positives = 420/732 (57%), Gaps = 70/732 (9%) Query: 2 SELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDR 61 SE ++LSFL + EK++IL VL+RDE ++K ++KRIR+LKNELLE KR+ K +Q + R Sbjct: 5 SEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGK--TQQEASR 62 Query: 62 TCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYD 121 C C +LG + + + C+ C+ VCR+CR+ NG+W+C VC K +L+ TG+WF++ Sbjct: 63 VCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122 Query: 122 QKVNRFAYRT--GSEIIRMS-LRHKPAVSKRETVGQSLLHQTQMGDIWP--GRKIIQERQ 176 +K RF G++++R S LR P + ++ Q+ + D P G+K + Sbjct: 123 EKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQT-RQDAEKSDTSPVAGKKASHDGP 181 Query: 177 KEPSVLFE-----------VPKLKSGKS-ALEAESESLDSFT----ADSDSTSRRDSLDK 220 K L PK +G+S +L+ + + S +D ST D D+ Sbjct: 182 KRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQ 241 Query: 221 ------------SGLFPEWKKMSAPKSQVEKET---QPGGQNVVFVDEGEMIFKKNTRKI 265 +G+ P + AP ++ + G +N + + E ++ T+ Sbjct: 242 EPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSH 301 Query: 266 LR---------------PSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEE 310 R S+ ++S +DL ++ RSKSVPG EE E Sbjct: 302 RRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETE 361 Query: 311 EDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQT 370 E ID LV + + SG S +++ SMMS+YSE GD+GN+ V+G I + Y +T Sbjct: 362 ESIDALVS-SQLSTNTHRLASGLSTTSLNSMMSVYSETGDYGNVKVSGEILLHISYCYKT 420 Query: 371 QSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRY 430 L + VK C LA DE K+R++ YVK+YLLPDKSR KRKT I+ T NP ++ETL+Y Sbjct: 421 GGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNNKRKTKIRTGT-NPEFNETLKY 479 Query: 431 EIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPT 490 I + L RTLQ SVWH+ RFGRN+FLGE EI DSW + D L K+ Sbjct: 480 TISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWNFENPTDEWFVLQPKVEFAPDI 539 Query: 491 GLPSHKGELVVSLKYIP-------------ASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 GL +KGEL V L+YIP +KT G +K+S GG L+V+IKEAKN Sbjct: 540 GL-QYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGKKKESPVISGGILEVFIKEAKN 598 Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 LTA K+GGTSDSFVKGYLLP +KA+K KT V+KK++NP +NHTF+++G+ +D++++CL Sbjct: 599 LTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNPQWNHTFMFSGIHPQDIKNVCL 658 Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGT 657 ELT+WD+E +SN FLGGVRL G+G+S+G+ VDWMDS GEE LWQKM PG+ EG Sbjct: 659 ELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQGEEQRLWQKMANNPGTPFEGV 718 Query: 658 LQLRSSMAKQKL 669 L LRSSM K +L Sbjct: 719 LMLRSSMGKCRL 730 >gi|254039648 synaptotagmin-like 5 isoform 2 [Homo sapiens] Length = 752 Score = 489 bits (1258), Expect = e-138 Identities = 300/753 (39%), Positives = 423/753 (56%), Gaps = 90/753 (11%) Query: 2 SELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDR 61 SE ++LSFL + EK++IL VL+RDE ++K ++KRIR+LKNELLE KR+ K +Q + R Sbjct: 5 SEFINLSFLLDHEKEMILGVLKRDEYLKKVEDKRIRKLKNELLEAKRRSGK--TQQEASR 62 Query: 62 TCARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYD 121 C C +LG + + + C+ C+ VCR+CR+ NG+W+C VC K +L+ TG+WF++ Sbjct: 63 VCVHCHRNLGLIFDRGDPCQACSLRVCRECRVAGPNGSWKCTVCDKIAQLRIITGEWFFE 122 Query: 122 QKVNRFAYRT--GSEIIRMS-LRHKPAVSKRETVGQSLLHQTQMGDIWP--GRKIIQERQ 176 +K RF G++++R S LR P + ++ Q+ + D P G+K + Sbjct: 123 EKAKRFKQVNVLGTDVVRQSILRRSPGAEEVQSQEQTR-QDAEKSDTSPVAGKKASHDGP 181 Query: 177 KEPSVLFE-----------VPKLKSGKS-ALEAESESLDSFTA----DSDSTSRRDSLDK 220 K L PK +G+S +L+ + + S + D ST D D+ Sbjct: 182 KRKGFLLSKFRSATRGEIITPKTDTGRSYSLDLDGQHFRSLKSPPGSDRGSTGSSDLNDQ 241 Query: 221 ------------SGLFPEWKKMSAPKSQVEKET---QPGGQNVVFVDEGEMIFKKNTRKI 265 +G+ P + AP ++ + G +N + + E ++ T+ Sbjct: 242 EPGPRTPKSSRSNGVTPGTQSSPAPSTRTVTSVISREYGFENSMDLAAIEGTSQELTKSH 301 Query: 266 LR---------------PSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEE 310 R S+ ++S +DL ++ RSKSVPG EE E Sbjct: 302 RRNTSGTPSIAVSGTSLSSDQSRSELDLSESFTEDSEDTVSIRSKSVPGALDKDSLEETE 361 Query: 311 EDIDHLVK------LHRQKLARS-SMQSGSSM--------------STIGSMMSIYSEAG 349 E ID LV HR S S Q+GS +++ SMMS+YSE G Sbjct: 362 ESIDALVSSQLSTNTHRLASGLSTSSQAGSDRKWTYLNVPDADSDTTSLNSMMSVYSETG 421 Query: 350 DFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQG 409 D+GN+ V+G I + Y +T L + VK C LA DE K+R++ YVK+YLLPDKSR Sbjct: 422 DYGNVKVSGEILLHISYCYKTGGLYIFVKNCRNLAIGDEKKQRTDAYVKSYLLPDKSRNN 481 Query: 410 KRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWK 469 KRKT I+ T NP ++ETL+Y I + L RTLQ SVWH+ RFGRN+FLGE EI DSW Sbjct: 482 KRKTKIRTGT-NPEFNETLKYTISHTQLETRTLQLSVWHYDRFGRNSFLGEVEIPFDSWN 540 Query: 470 LDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIP-------------ASKTPVGGD 516 + D L K+ GL +KGEL V L+YIP +KT G Sbjct: 541 FENPTDEWFVLQPKVEFAPDIGL-QYKGELTVVLRYIPPEENLMLPPEQLQGNKTFKKGK 599 Query: 517 RKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNP 576 +K+S GG L+V+IKEAKNLTA K+GGTSDSFVKGYLLP +KA+K KT V+KK++NP Sbjct: 600 KKESPVISGGILEVFIKEAKNLTAVKSGGTSDSFVKGYLLPDDSKATKHKTLVIKKSVNP 659 Query: 577 HYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDST 636 +NHTF+++G+ +D++++CLELT+WD+E +SN FLGGVRL G+G+S+G+ VDWMDS Sbjct: 660 QWNHTFMFSGIHPQDIKNVCLELTIWDKEAFSSNIFLGGVRLNSGSGVSHGKNVDWMDSQ 719 Query: 637 GEEVSLWQKMRQYPGSWAEGTLQLRSSMAKQKL 669 GEE LWQKM PG+ EG L LRSSM K +L Sbjct: 720 GEEQRLWQKMANNPGTPFEGVLMLRSSMGKCRL 752 >gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens] Length = 1256 Score = 301 bits (771), Expect = 1e-81 Identities = 188/535 (35%), Positives = 287/535 (53%), Gaps = 40/535 (7%) Query: 153 GQSLLHQTQMGDIWPGRKIIQERQKEPSVLFEVPKLKSGKSALE---------------- 196 GQ L + G+ + + RQ P ++ + K+ K L Sbjct: 727 GQGTLQEPGFGEASEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEG 786 Query: 197 -AESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQPGGQNVVFVDEGE 255 +ES+ D T+ + + R S + P K + +S K +++ + Sbjct: 787 FSESDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLE--RSAARKMPSKSLEDISSDSSNQ 844 Query: 256 MIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEEDI-D 314 +++R +E S + +P++ L SKSVP D ++ E + + Sbjct: 845 AKVDNQPEELVRSAEDV-STVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASE 903 Query: 315 HLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSLKYE 367 +L R K + SS+ + SS S + GS+MS+YS GDFGN+ V G I F+++Y Sbjct: 904 SSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYV 961 Query: 368 QQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDET 427 + + L V V +C LA AD K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y+E Sbjct: 962 ESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEI 1021 Query: 428 LRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAE 487 LRY+I + +L + L S+WH F RN+FLGE E+ +++W D K + L + Sbjct: 1022 LRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKT 1081 Query: 488 SPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGT 546 +P L + ++GE+ ++L+Y+P PV G + + GE+ +W+KE +L + G Sbjct: 1082 APVALEAENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR-GSH 1133 Query: 547 SDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREP 606 +SFVK +LP ++ S++KT + KT NP +NHT VY+G R EDL C+ELTVWD Sbjct: 1134 LNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYK 1193 Query: 607 LASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661 L +N FLGG+R+G GTG S G VDWMDST EEV+LW+KM P +W E TL LR Sbjct: 1194 L-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1247 >gi|46255062 synaptotagmin-like 2 isoform c [Homo sapiens] Length = 1272 Score = 298 bits (764), Expect = 8e-81 Identities = 189/538 (35%), Positives = 284/538 (52%), Gaps = 23/538 (4%) Query: 133 SEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLFEVPKLKSGK 192 SE I +S +P + + ++ P K +E +KE F G Sbjct: 740 SEAISVSRNRQPIPLLMNKENSTKTSKVELTLASPYMKQEKEEEKEG---FSESDFSDGN 796 Query: 193 SALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQPGGQNVVFVD 252 ++ AES S + + S + + K + S + + Q V Sbjct: 797 TSSNAESWRNPSSSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVR 856 Query: 253 EGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEED 312 E K + + + S + +P++ L SKSVP D ++ E + Sbjct: 857 SAEDDEKPDQKPVTNECVPRISTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDT 916 Query: 313 I-DHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSL 364 + +L R K + SS+ + SS S + GS+MS+YS GDFGN+ V G I F++ Sbjct: 917 ASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAI 974 Query: 365 KYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLY 424 +Y + + L V V +C LA AD K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y Sbjct: 975 EYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVY 1034 Query: 425 DETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKI 484 +E LRY+I + +L + L S+WH F RN+FLGE E+ +++W D K + L + Sbjct: 1035 NEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLK 1094 Query: 485 SAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKA 543 +P L + ++GE+ ++L+Y+P PV G + + GE+ +W+KE +L + Sbjct: 1095 RKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR- 1146 Query: 544 GGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWD 603 G +SFVK +LP ++ S++KT + KT NP +NHT VY+G R EDL C+ELTVWD Sbjct: 1147 GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWD 1206 Query: 604 REPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661 L +N FLGG+R+G GTG S G VDWMDST EEV+LW+KM P +W E TL LR Sbjct: 1207 HYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 1263 >gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] Length = 935 Score = 298 bits (762), Expect = 1e-80 Identities = 169/409 (41%), Positives = 246/409 (60%), Gaps = 25/409 (6%) Query: 267 RPSEYTKSVIDL-----RPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEEDI-DHLVKLH 320 +P E +S D+ +P++ L SKSVP D ++ E + + +L Sbjct: 529 QPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLS 588 Query: 321 RQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSL 373 R K + SS+ + SS S + GS+MS+YS GDFGN+ V G I F+++Y + + L Sbjct: 589 RHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKEL 646 Query: 374 VVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIP 433 V V +C LA AD K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y+E LRY+I Sbjct: 647 HVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIE 706 Query: 434 ESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLP 493 + +L + L S+WH F RN+FLGE E+ +++W D K + L + +P L Sbjct: 707 KQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALE 766 Query: 494 S-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552 + ++GE+ ++L+Y+P PV G + + GE+ +W+KE +L + G +SFVK Sbjct: 767 AENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR-GSHLNSFVK 818 Query: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612 +LP ++ S++KT + KT NP +NHT VY+G R EDL C+ELTVWD L +N F Sbjct: 819 CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQF 877 Query: 613 LGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661 LGG+R+G GTG S G VDWMDST EEV+LW+KM P +W E TL LR Sbjct: 878 LGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 926 Score = 51.6 bits (122), Expect = 2e-06 Identities = 53/244 (21%), Positives = 101/244 (41%), Gaps = 17/244 (6%) Query: 4 LLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTC 63 ++DLSFL+EEE++ I+ VLQRD +++A+E+R+R L ++ + ++ G Y + Sbjct: 1 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60 Query: 64 ARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYDQK 123 + G + + + + + +E+ AKE + D F + Sbjct: 61 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENG--------AKESWVNNVNKDAFLPPE 112 Query: 124 VNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLF 183 + + S V+ +V T+ ++ P ++++K P F Sbjct: 113 LAGVVEEPEEDAAPAS-PSSSVVNPASSVIDMSQENTRKPNVSP-----EKQRKNP---F 163 Query: 184 EVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQP 243 KL G S+ + ++E + TS+ D L +S S K + K+T P Sbjct: 164 NSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLP 223 Query: 244 GGQN 247 G N Sbjct: 224 GLSN 227 >gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] Length = 934 Score = 298 bits (762), Expect = 1e-80 Identities = 169/409 (41%), Positives = 246/409 (60%), Gaps = 25/409 (6%) Query: 267 RPSEYTKSVIDL-----RPEDVVHESGSLGDRSKSVPGLNVDMEEEEEEEDI-DHLVKLH 320 +P E +S D+ +P++ L SKSVP D ++ E + + +L Sbjct: 528 QPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLS 587 Query: 321 RQKLARSSMQSGSSMSTI-------GSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSL 373 R K + SS+ + SS S + GS+MS+YS GDFGN+ V G I F+++Y + + L Sbjct: 588 RHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKEL 645 Query: 374 VVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIP 433 V V +C LA AD K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y+E LRY+I Sbjct: 646 HVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIE 705 Query: 434 ESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLP 493 + +L + L S+WH F RN+FLGE E+ +++W D K + L + +P L Sbjct: 706 KQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALE 765 Query: 494 S-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552 + ++GE+ ++L+Y+P PV G + + GE+ +W+KE +L + G +SFVK Sbjct: 766 AENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR-GSHLNSFVK 817 Query: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612 +LP ++ S++KT + KT NP +NHT VY+G R EDL C+ELTVWD L +N F Sbjct: 818 CTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQF 876 Query: 613 LGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661 LGG+R+G GTG S G VDWMDST EEV+LW+KM P +W E TL LR Sbjct: 877 LGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 925 Score = 52.4 bits (124), Expect = 1e-06 Identities = 54/244 (22%), Positives = 100/244 (40%), Gaps = 18/244 (7%) Query: 4 LLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTC 63 ++DLSFL+EEE++ I+ VLQRD +++A+E+R+R L ++ + ++ G Y + Sbjct: 1 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60 Query: 64 ARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYDQK 123 + G + + + + + +E+ AKE + D F + Sbjct: 61 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENG--------AKESWVNNVNKDAFLPPE 112 Query: 124 VNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLF 183 + + S V+ +V T+ ++ P E++K P F Sbjct: 113 LAGVVEEPEEDAAPAS-PSSSVVNPASSVIDMSQENTRKPNVSP------EKRKNP---F 162 Query: 184 EVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQP 243 KL G S+ + ++E + TS+ D L +S S K + K+T P Sbjct: 163 NSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLP 222 Query: 244 GGQN 247 G N Sbjct: 223 GLSN 226 >gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens] Length = 376 Score = 294 bits (752), Expect = 2e-79 Identities = 163/377 (43%), Positives = 234/377 (62%), Gaps = 20/377 (5%) Query: 294 SKSVPGLNVDMEEEEEEEDI-DHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIY 345 SKSVP D ++ E + + +L R K + SS+ + SS S + GS+MS+Y Sbjct: 2 SKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVY 61 Query: 346 SEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDK 405 S GDFGN+ V G I F+++Y + + L V V +C LA AD K+RS+PYVK YLLPDK Sbjct: 62 S--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDK 119 Query: 406 SRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQM 465 + GK+KT + + T+NP+Y+E LRY+I + +L + L S+WH F RN+FLGE E+ + Sbjct: 120 GKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDL 179 Query: 466 DSWKLDKKLDHCLPLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGE 524 ++W D K + L + +P L + ++GE+ ++L+Y+P PV G + + Sbjct: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT--- 233 Query: 525 GGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVY 584 GE+ +W+KE +L + G +SFVK +LP ++ S++KT + KT NP +NHT VY Sbjct: 234 -GEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 291 Query: 585 NGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQ 644 +G R EDL C+ELTVWD L +N FLGG+R+G GTG S G VDWMDST EEV+LW+ Sbjct: 292 DGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWE 350 Query: 645 KMRQYPGSWAEGTLQLR 661 KM P +W E TL LR Sbjct: 351 KMVNSPNTWIEATLPLR 367 >gi|46255066 synaptotagmin-like 2 isoform e [Homo sapiens] Length = 376 Score = 294 bits (752), Expect = 2e-79 Identities = 163/377 (43%), Positives = 234/377 (62%), Gaps = 20/377 (5%) Query: 294 SKSVPGLNVDMEEEEEEEDI-DHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIY 345 SKSVP D ++ E + + +L R K + SS+ + SS S + GS+MS+Y Sbjct: 2 SKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVY 61 Query: 346 SEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDK 405 S GDFGN+ V G I F+++Y + + L V V +C LA AD K+RS+PYVK YLLPDK Sbjct: 62 S--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDK 119 Query: 406 SRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQM 465 + GK+KT + + T+NP+Y+E LRY+I + +L + L S+WH F RN+FLGE E+ + Sbjct: 120 GKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDL 179 Query: 466 DSWKLDKKLDHCLPLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGE 524 ++W D K + L + +P L + ++GE+ ++L+Y+P PV G + + Sbjct: 180 ETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT--- 233 Query: 525 GGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVY 584 GE+ +W+KE +L + G +SFVK +LP ++ S++KT + KT NP +NHT VY Sbjct: 234 -GEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 291 Query: 585 NGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQ 644 +G R EDL C+ELTVWD L +N FLGG+R+G GTG S G VDWMDST EEV+LW+ Sbjct: 292 DGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWE 350 Query: 645 KMRQYPGSWAEGTLQLR 661 KM P +W E TL LR Sbjct: 351 KMVNSPNTWIEATLPLR 367 >gi|46255068 synaptotagmin-like 2 isoform f [Homo sapiens] Length = 365 Score = 289 bits (739), Expect = 7e-78 Identities = 155/364 (42%), Positives = 227/364 (62%), Gaps = 16/364 (4%) Query: 303 DMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTI----GSMMSIYSEAGDFGNIFVTG 358 D E + E L + + + +++ S S M+++ GS+MS+YS GDFGN+ V G Sbjct: 4 DRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYS--GDFGNLEVKG 61 Query: 359 RIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRD 418 I F+++Y + + L V V +C LA AD K+RS+PYVK YLLPDK + GK+KT + + Sbjct: 62 NIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKK 121 Query: 419 TINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCL 478 T+NP+Y+E LRY+I + +L + L S+WH F RN+FLGE E+ +++W D K + L Sbjct: 122 TLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL 181 Query: 479 PLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 + +P L + ++GE+ ++L+Y+P PV G + + GE+ +W+KE + Sbjct: 182 RWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLD 234 Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 L + G +SFVK +LP ++ S++KT + KT NP +NHT VY+G R EDL C+ Sbjct: 235 LPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACV 293 Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGT 657 ELTVWD L +N FLGG+R+G GTG S G VDWMDST EEV+LW+KM P +W E T Sbjct: 294 ELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEAT 352 Query: 658 LQLR 661 L LR Sbjct: 353 LPLR 356 >gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] Length = 910 Score = 285 bits (729), Expect = 1e-76 Identities = 153/345 (44%), Positives = 217/345 (62%), Gaps = 14/345 (4%) Query: 320 HRQKLARSSMQSGSSMS--TIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHV 377 H KL R S + + GS+MS+YS GDFGN+ V G I F+++Y + + L V V Sbjct: 568 HPDKLKRMSKSVPAFLQDEVSGSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFV 625 Query: 378 KECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLL 437 +C LA AD K+RS+PYVK YLLPDK + GK+KT + + T+NP+Y+E LRY+I + +L Sbjct: 626 AQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQIL 685 Query: 438 AQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPS-HK 496 + L S+WH F RN+FLGE E+ +++W D K + L + +P L + ++ Sbjct: 686 KTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENR 745 Query: 497 GELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLL 556 GE+ ++L+Y+P PV G + + GE+ +W+KE +L + G +SFVK +L Sbjct: 746 GEMKLALQYVP---EPVPGKKLPTT----GEVHIWVKECLDLPLLR-GSHLNSFVKCTIL 797 Query: 557 PMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGV 616 P ++ S++KT + KT NP +NHT VY+G R EDL C+ELTVWD L +N FLGG+ Sbjct: 798 PDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGL 856 Query: 617 RLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYPGSWAEGTLQLR 661 R+G GTG S G VDWMDST EEV+LW+KM P +W E TL LR Sbjct: 857 RIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLR 901 Score = 52.4 bits (124), Expect = 1e-06 Identities = 54/244 (22%), Positives = 100/244 (40%), Gaps = 18/244 (7%) Query: 4 LLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTC 63 ++DLSFL+EEE++ I+ VLQRD +++A+E+R+R L ++ + ++ G Y + Sbjct: 1 MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAK 60 Query: 64 ARCQESLGRLSPKTNTCRGCNHLVCRDCRIQESNGTWRCKVCAKEIELKKATGDWFYDQK 123 + G + + + + + +E+ AKE + D F + Sbjct: 61 RHRDKIHGADIIRASMRKKRPQIAAEQSKDRENG--------AKESWVNNVNKDAFLPPE 112 Query: 124 VNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKEPSVLF 183 + + S V+ +V T+ ++ P E++K P F Sbjct: 113 LAGVVEEPEEDAAPAS-PSSSVVNPASSVIDMSQENTRKPNVSP------EKRKNP---F 162 Query: 184 EVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWKKMSAPKSQVEKETQP 243 KL G S+ + ++E + TS+ D L +S S K + K+T P Sbjct: 163 NSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQTLP 222 Query: 244 GGQN 247 G N Sbjct: 223 GLSN 226 >gi|244790016 synaptotagmin-like 2 isoform h [Homo sapiens] Length = 336 Score = 284 bits (726), Expect = 2e-76 Identities = 148/324 (45%), Positives = 210/324 (64%), Gaps = 12/324 (3%) Query: 339 GSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVK 398 GS+MS+YS GDFGN+ V G I F+++Y + + L V V +C LA AD K+RS+PYVK Sbjct: 15 GSVMSVYS--GDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVK 72 Query: 399 TYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFL 458 YLLPDK + GK+KT + + T+NP+Y+E LRY+I + +L + L S+WH F RN+FL Sbjct: 73 AYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFL 132 Query: 459 GEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPS-HKGELVVSLKYIPASKTPVGGDR 517 GE E+ +++W D K + L + +P L + ++GE+ ++L+Y+P PV G + Sbjct: 133 GEVELDLETWDWDNKQNKQLRWYPLKRKTAPVALEAENRGEMKLALQYVP---EPVPGKK 189 Query: 518 KKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPH 577 + GE+ +W+KE +L + G +SFVK +LP ++ S++KT + KT NP Sbjct: 190 LPTT----GEVHIWVKECLDLPLLR-GSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPI 244 Query: 578 YNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTG 637 +NHT VY+G R EDL C+ELTVWD L +N FLGG+R+G GTG S G VDWMDST Sbjct: 245 FNHTMVYDGFRPEDLMEACVELTVWDHYKL-TNQFLGGLRIGFGTGKSYGTEVDWMDSTS 303 Query: 638 EEVSLWQKMRQYPGSWAEGTLQLR 661 EEV+LW+KM P +W E TL LR Sbjct: 304 EEVALWEKMVNSPNTWIEATLPLR 327 >gi|14249614 synaptotagmin-like 1 [Homo sapiens] Length = 550 Score = 263 bits (671), Expect = 5e-70 Identities = 188/558 (33%), Positives = 286/558 (51%), Gaps = 87/558 (15%) Query: 110 ELKKATGDWFYDQKVNRFAY-RTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPG 168 +LK TGDWF + + R GS+++R S+R K ++ GD PG Sbjct: 75 QLKILTGDWFQEARSQRHHNAHFGSDLVRASMRRK---------------KSTRGDQAPG 119 Query: 169 RKIIQERQKEPSVLFEVPKLKSGKSALEAESESLDSFTADSDSTSRRDSLDKSGLFPEWK 228 +R+ E +V + + + EA E L T SD + + G + Sbjct: 120 H----DREAEAAVKEKEEGPEPRLTIDEAPQERLRE-TEASDPEEASQAQEDPGQGDQ-- 172 Query: 229 KMSAPKSQVEKETQPGGQNVVFVDEGEMIFKKNTRKILRPSEYTKSVIDLRPEDVVHESG 288 ++ A ++ E E GG+ + RP+ ++ Sbjct: 173 QVCAEEADPELEPASGGEQ-----------------------------EPRPQQAQTKAA 203 Query: 289 S-LGDRSKSVPGLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSE 347 S + + + PG + ++ R + SS+ S +S + GS MS+ Sbjct: 204 SQILENGEEAPGPDPSLD---------------RMLSSSSSVSSLNSSTLSGSQMSL--- 245 Query: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407 +GD + V G + F+L YE L VHV +C LA A ++RS+PYVK+YLLPDK Sbjct: 246 SGDAEAVQVRGSVHFALHYEPGAAELRVHVIQCQGLAAA--RRRRSDPYVKSYLLPDK-- 301 Query: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467 Q KRKT++K+ +NP+++ETLRY +P++ L R L SVWH GRN FLGE E+ +D+ Sbjct: 302 QSKRKTAVKKRNLNPVFNETLRYSVPQAELQGRVLSLSVWHRESLGRNIFLGEVEVPLDT 361 Query: 468 WKLDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGE 527 W + LPL ++ SP LPS +G L +SLKY+PA G GE Sbjct: 362 WDWGSE-PTWLPLQPRV-PPSPDDLPS-RGLLALSLKYVPAGSEGAGLP-------PSGE 411 Query: 528 LQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGV 587 L W+KEA++L +A G+ D++V+ ++LP ++AS+++T V++++L+P +NHT VY+G Sbjct: 412 LHFWVKEARDLLPLRA-GSLDTYVQCFVLPDDSQASRQRTRVVRRSLSPVFNHTMVYDGF 470 Query: 588 RLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMR 647 DL+ C EL++WD LA N LGG RL +GTG S G V WMDST EE LWQ + Sbjct: 471 GPADLRQACAELSLWDHGALA-NRQLGGTRLSLGTGSSYGLQVPWMDSTPEEKQLWQALL 529 Query: 648 QYPGSWAEGTLQLRSSMA 665 + P W +G L LR+++A Sbjct: 530 EQPCEWVDGLLPLRTNLA 547 Score = 43.9 bits (102), Expect = 5e-04 Identities = 20/37 (54%), Positives = 29/37 (78%) Query: 4 LLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLK 40 LLDLSFL+EEE++ I VLQRD +R+ +E R+ +L+ Sbjct: 31 LLDLSFLTEEEQEAIAGVLQRDARLRQLEEGRVSKLR 67 >gi|110227631 synaptotagmin-like 3 [Homo sapiens] Length = 542 Score = 213 bits (543), Expect = 4e-55 Identities = 141/389 (36%), Positives = 203/389 (52%), Gaps = 40/389 (10%) Query: 293 RSKSVPGLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSGSSMSTI-------GSMMSIY 345 R S P + + +E+ + + ++K + ++ S + STI GS++SI Sbjct: 172 RKVSAPDILKPLNQEDPKCSTNPILK-------QQNLPSSPAPSTIFSGGFRHGSLISID 224 Query: 346 S---EAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLL 402 S E G+F N VTG I F++ Y +T SL + +K C LAY +E KK+ NPYVKTYLL Sbjct: 225 STCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLL 284 Query: 403 PDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAE 462 PD+S QGKRKT ++R+T++P + ETL+Y++ + L R LQ SVWH G R FLGE Sbjct: 285 PDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVI 344 Query: 463 IQMDSWKLDKKLDHCL---PLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKK 519 I + +W + PL K + + +P GEL V K + S+ RK Sbjct: 345 IPLATWDFEDSTTQSFRWHPLRAK-AEKYEDSVPQSNGELTVRAKLVLPSR-----PRKL 398 Query: 520 SKGGEG-------GELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKK 572 + EG G+L + + AKNL + GT +SFVKG L + + K+PV++K Sbjct: 399 QEAQEGTDQPSLHGQLCLVVLGAKNL-PVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRK 457 Query: 573 TLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASND-FLGGVRLGVGTGISNGEVVD 631 P + H+FV++GV L+ LELTVWD+ ND LGG RLG S G+ Sbjct: 458 QACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLG-----SKGDTAV 512 Query: 632 WMDSTGEEVSLWQKMRQYPGSWAEGTLQL 660 D+ WQK+ P W + TL L Sbjct: 513 GGDACSLSKLQWQKVLSSPNLWTDMTLVL 541 Score = 119 bits (299), Expect = 7e-27 Identities = 61/162 (37%), Positives = 89/162 (54%), Gaps = 17/162 (10%) Query: 1 MSELLDLSFLSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSD 60 M++ +DLS L E E++ IL VL RD+ V+ +E+R R+LK L ++ KGAK + + Sbjct: 1 MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKE 60 Query: 61 RTCARCQESLGRLSPKTNTCRGCNHLVCRDCRI-QESNGTWRCKVCAKEIELKKATGDWF 119 + CARCQ+ LG L + CRGC+H VC CR+ W+C VC ++ +K TG+WF Sbjct: 61 KCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWF 120 Query: 120 YDQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQ 161 Y+++ +F P K ETVG LL Q Sbjct: 121 YEERAKKF----------------PTGGKHETVGGQLLQSYQ 146 >gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] Length = 694 Score = 173 bits (438), Expect = 5e-43 Identities = 170/668 (25%), Positives = 275/668 (41%), Gaps = 116/668 (17%) Query: 10 LSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQES 69 L++EEK++I V+ R E++ + +++RI RL + L +++ A G C C E Sbjct: 50 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNR-----CILCGEQ 104 Query: 70 LGRLSPKTNTCRGCNHLVCRDCRIQESN---GTWRCKVCAKEIELKKATGDWFY------ 120 LG L C C VC C ++ +N W CK+C ++ E+ K +G WF+ Sbjct: 105 LGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQ 164 Query: 121 --DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKE 178 Q + + + + +PA + ++ PG+K + Sbjct: 165 VLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSE-DRRGPGQKTGPDPASA 223 Query: 179 PSVLFEVPKLKSGK----SALEAESESLDSFTADSDST------SRRDSLDKSGLFPEWK 228 P P ++ S+ +SES D DS+ R +S+ S P Sbjct: 224 PGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSV 283 Query: 229 KMSAPKSQVEKETQPGGQNV------VFVDEGEMIFKKNTRKILRPSEYTKS------VI 276 + AP + T PGG F D+ + + P E + Sbjct: 284 QSPAPPQPGQPGT-PGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAV 342 Query: 277 DLRPEDVVHESGSLGDRSKSVP----GLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSG 332 R + + H SG S + P EEEEEE ++ Sbjct: 343 GAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEE---------------ANSYDS 387 Query: 333 SSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKR 392 +T+G+ + FSL Y+Q SL + + L D + Sbjct: 388 DEATTLGA-------------------LEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGL 427 Query: 393 SNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYE-IPESLLAQRTLQFSVWHHGR 451 ++PYVK +LLP S+ K +T R+T NP+++ETL Y I + + ++TL+ SV + Sbjct: 428 ADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDK 487 Query: 452 FGRNTFLGEAEIQMDSWKLDKK------LDHCLPLHGKISAESPTGLP------------ 493 FG N F+GE + K +++ L+ +P+ + S G+ Sbjct: 488 FGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGD 547 Query: 494 -SHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552 +G+++VSL Y T GG L V I +L A A G SD FVK Sbjct: 548 IEERGKILVSLMY----STQQGG------------LIVGIIRCVHLAAMDANGYSDPFVK 591 Query: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612 +L P K +K KT + KKTLNP +N F Y+ ++ DL L+++VWD + SND+ Sbjct: 592 LWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGKSNDY 650 Query: 613 LGGVRLGV 620 +GG +LG+ Sbjct: 651 IGGCQLGI 658 >gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] Length = 690 Score = 173 bits (438), Expect = 5e-43 Identities = 170/668 (25%), Positives = 275/668 (41%), Gaps = 116/668 (17%) Query: 10 LSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQES 69 L++EEK++I V+ R E++ + +++RI RL + L +++ A G C C E Sbjct: 46 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNR-----CILCGEQ 100 Query: 70 LGRLSPKTNTCRGCNHLVCRDCRIQESN---GTWRCKVCAKEIELKKATGDWFY------ 120 LG L C C VC C ++ +N W CK+C ++ E+ K +G WF+ Sbjct: 101 LGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQ 160 Query: 121 --DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKE 178 Q + + + + +PA + ++ PG+K + Sbjct: 161 VLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSE-DRRGPGQKTGPDPASA 219 Query: 179 PSVLFEVPKLKSGK----SALEAESESLDSFTADSDST------SRRDSLDKSGLFPEWK 228 P P ++ S+ +SES D DS+ R +S+ S P Sbjct: 220 PGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSV 279 Query: 229 KMSAPKSQVEKETQPGGQNV------VFVDEGEMIFKKNTRKILRPSEYTKS------VI 276 + AP + T PGG F D+ + + P E + Sbjct: 280 QSPAPPQPGQPGT-PGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAV 338 Query: 277 DLRPEDVVHESGSLGDRSKSVP----GLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSG 332 R + + H SG S + P EEEEEE ++ Sbjct: 339 GAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEE---------------ANSYDS 383 Query: 333 SSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKR 392 +T+G+ + FSL Y+Q SL + + L D + Sbjct: 384 DEATTLGA-------------------LEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGL 423 Query: 393 SNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYE-IPESLLAQRTLQFSVWHHGR 451 ++PYVK +LLP S+ K +T R+T NP+++ETL Y I + + ++TL+ SV + Sbjct: 424 ADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDK 483 Query: 452 FGRNTFLGEAEIQMDSWKLDKK------LDHCLPLHGKISAESPTGLP------------ 493 FG N F+GE + K +++ L+ +P+ + S G+ Sbjct: 484 FGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGD 543 Query: 494 -SHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552 +G+++VSL Y T GG L V I +L A A G SD FVK Sbjct: 544 IEERGKILVSLMY----STQQGG------------LIVGIIRCVHLAAMDANGYSDPFVK 587 Query: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612 +L P K +K KT + KKTLNP +N F Y+ ++ DL L+++VWD + SND+ Sbjct: 588 LWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGKSNDY 646 Query: 613 LGGVRLGV 620 +GG +LG+ Sbjct: 647 IGGCQLGI 654 >gi|211059429 synaptotagmin II [Homo sapiens] Length = 419 Score = 146 bits (368), Expect = 7e-35 Identities = 89/277 (32%), Positives = 147/277 (53%), Gaps = 27/277 (9%) Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 G++ FSL Y+ Q L V V + +L D S+PYVK +LLPDK + K +T + R Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197 Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477 T+NP ++ET +++P L +TL +++ RF ++ +GE ++ M++ L + ++ Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257 Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 L G E P G++ SL+Y+P + G+L V I EAKN Sbjct: 258 RDLQGGEKEE-----PEKLGDICTSLRYVPTA----------------GKLTVCILEAKN 296 Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 L GG SD +VK +L+ + K+KT V KKTLNP++N +F + + E +Q + + Sbjct: 297 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQV 355 Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMD 634 +TV D + L N+ +G ++ VG+ + E+ W D Sbjct: 356 VVTVLDYDKLGKNEAIG--KIFVGSNATGTELRHWSD 390 Score = 68.6 bits (166), Expect = 2e-11 Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 3/116 (2%) Query: 524 EGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFV 583 + +L V + +A L A GGTSD +VK +LLP +K K +T V +KTLNP +N TF Sbjct: 152 QANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP--DKKKKYETKVHRKTLNPAFNETFT 209 Query: 584 YNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEE 639 + V ++L L + ++D + + +D +G V++ + T + +W D G E Sbjct: 210 FK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 264 >gi|31543670 synaptotagmin II [Homo sapiens] Length = 419 Score = 146 bits (368), Expect = 7e-35 Identities = 89/277 (32%), Positives = 147/277 (53%), Gaps = 27/277 (9%) Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 G++ FSL Y+ Q L V V + +L D S+PYVK +LLPDK + K +T + R Sbjct: 141 GKLQFSLDYDFQANQLTVGVLQAAELPALDMGGT-SDPYVKVFLLPDKKK--KYETKVHR 197 Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477 T+NP ++ET +++P L +TL +++ RF ++ +GE ++ M++ L + ++ Sbjct: 198 KTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEW 257 Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 L G E P G++ SL+Y+P + G+L V I EAKN Sbjct: 258 RDLQGGEKEE-----PEKLGDICTSLRYVPTA----------------GKLTVCILEAKN 296 Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 L GG SD +VK +L+ + K+KT V KKTLNP++N +F + + E +Q + + Sbjct: 297 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQV 355 Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMD 634 +TV D + L N+ +G ++ VG+ + E+ W D Sbjct: 356 VVTVLDYDKLGKNEAIG--KIFVGSNATGTELRHWSD 390 Score = 68.6 bits (166), Expect = 2e-11 Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 3/116 (2%) Query: 524 EGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFV 583 + +L V + +A L A GGTSD +VK +LLP +K K +T V +KTLNP +N TF Sbjct: 152 QANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP--DKKKKYETKVHRKTLNPAFNETFT 209 Query: 584 YNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEE 639 + V ++L L + ++D + + +D +G V++ + T + +W D G E Sbjct: 210 FK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEEWRDLQGGE 264 >gi|92859638 synaptotagmin V [Homo sapiens] Length = 386 Score = 143 bits (360), Expect = 6e-34 Identities = 94/291 (32%), Positives = 145/291 (49%), Gaps = 26/291 (8%) Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 GR+ +SL Y+ Q+ L+V + + LA D S+PYV+ YLLPDK R + +T + R Sbjct: 110 GRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGS-SDPYVRVYLLPDKRR--RYETKVHR 166 Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477 T+NP + ET +++P L R L +V+ RF RN +GE + M S L + + Sbjct: 167 QTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAW 226 Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 L +P G++ SL+Y+P + G+L V + EAKN Sbjct: 227 RELQA-----APREEQEKLGDICFSLRYVPTA----------------GKLTVIVLEAKN 265 Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 L GG SD +VK +LL K K+KT + K TLNP+YN F + V + +Q + + Sbjct: 266 LKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE-VPCDQVQKVQV 324 Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISN-GEVVDWMDSTGEEVSLWQKMR 647 ELTV D + L N+ +G V +G G + D + + ++ W +R Sbjct: 325 ELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLR 375 >gi|6005997 double C2-like domains, beta [Homo sapiens] Length = 412 Score = 139 bits (349), Expect = 1e-32 Identities = 102/316 (32%), Positives = 152/316 (48%), Gaps = 22/316 (6%) Query: 308 EEEEDIDHLVKLHRQKLARSSMQSGSSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYE 367 E++ED+D L + S S + ++ + + G + FSL Y+ Sbjct: 78 EDDEDVDQLFGAYGSSPGPSPGPSPARPPAKPPEDEPDADGYESDDCTALGTLDFSLLYD 137 Query: 368 QQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDET 427 Q+ +L + + L D ++PYVK +LLP S+ K +T R+T+NP ++ET Sbjct: 138 QENNALHCTITKAKGLKPMDH-NGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNET 196 Query: 428 LRYE-IPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLD--KKLDHCLPLHGKI 484 L Y I + + ++TL+ SV +F N F+GE + + K + K + CL + Sbjct: 197 LTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFNICLEKQLPV 256 Query: 485 SAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAG 544 L +G +++SLKY K G L V I +L A A Sbjct: 257 DKTEDKSL-EERGRILISLKY------------SSQKQG----LLVGIVRCAHLAAMDAN 299 Query: 545 GTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDR 604 G SD +VK YL P +K SK KT V KKTLNP +N F Y ++ DL LE+TVWD Sbjct: 300 GYSDPYVKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYE-IKHGDLAKKSLEVTVWDY 358 Query: 605 EPLASNDFLGGVRLGV 620 + SNDF+GGV LG+ Sbjct: 359 DIGKSNDFIGGVVLGI 374 >gi|209447073 synaptotagmin I [Homo sapiens] Length = 422 Score = 135 bits (339), Expect = 2e-31 Identities = 89/293 (30%), Positives = 145/293 (49%), Gaps = 38/293 (12%) Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 G++ +SL Y+ Q L+V + + +L D S+PYVK +LLPDK + K +T + R Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETKVHR 200 Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477 T+NP+++E +++P S L +TL +V+ RF ++ +GE ++ M++ + Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260 Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 L E G++ SL+Y+P + G+L V I EAKN Sbjct: 261 RDLQSAEKEEQ-----EKLGDICFSLRYVPTA----------------GKLTVVILEAKN 299 Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 L GG SD +VK +L+ + K+KT + K TLNP+YN +F + V E +Q + + Sbjct: 300 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQV 358 Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650 +TV D + + ND +G V +G +STG E+ W M P Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSDMLANP 398 >gi|5032139 synaptotagmin I [Homo sapiens] Length = 422 Score = 135 bits (339), Expect = 2e-31 Identities = 89/293 (30%), Positives = 145/293 (49%), Gaps = 38/293 (12%) Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 G++ +SL Y+ Q L+V + + +L D S+PYVK +LLPDK + K +T + R Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETKVHR 200 Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477 T+NP+++E +++P S L +TL +V+ RF ++ +GE ++ M++ + Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260 Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 L E G++ SL+Y+P + G+L V I EAKN Sbjct: 261 RDLQSAEKEEQ-----EKLGDICFSLRYVPTA----------------GKLTVVILEAKN 299 Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 L GG SD +VK +L+ + K+KT + K TLNP+YN +F + V E +Q + + Sbjct: 300 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQV 358 Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650 +TV D + + ND +G V +G +STG E+ W M P Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSDMLANP 398 >gi|209447070 synaptotagmin I [Homo sapiens] Length = 422 Score = 135 bits (339), Expect = 2e-31 Identities = 89/293 (30%), Positives = 145/293 (49%), Gaps = 38/293 (12%) Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 G++ +SL Y+ Q L+V + + +L D S+PYVK +LLPDK + K +T + R Sbjct: 144 GKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGT-SDPYVKVFLLPDKKK--KFETKVHR 200 Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHC 477 T+NP+++E +++P S L +TL +V+ RF ++ +GE ++ M++ + Sbjct: 201 KTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFGHVTEEW 260 Query: 478 LPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKN 537 L E G++ SL+Y+P + G+L V I EAKN Sbjct: 261 RDLQSAEKEEQ-----EKLGDICFSLRYVPTA----------------GKLTVVILEAKN 299 Query: 538 LTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCL 597 L GG SD +VK +L+ + K+KT + K TLNP+YN +F + V E +Q + + Sbjct: 300 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFE-VPFEQIQKVQV 358 Query: 598 ELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTGEEVSLWQKMRQYP 650 +TV D + + ND +G V +G +STG E+ W M P Sbjct: 359 VVTVLDYDKIGKNDAIGKVFVG-------------YNSTGAELRHWSDMLANP 398 >gi|38570146 synaptotagmin VII [Homo sapiens] Length = 403 Score = 131 bits (330), Expect = 2e-30 Identities = 96/300 (32%), Positives = 149/300 (49%), Gaps = 44/300 (14%) Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 GRI FS+ Y Q +L V + + +L A + S+P+VK YLLPDK K +T +KR Sbjct: 137 GRIQFSVGYNFQESTLTVKIMKAQELP-AKDFSGTSDPFVKIYLLPDKKH--KLETKVKR 193 Query: 418 DTINPLYDETLRYE-IPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDSWKLD----- 471 +NP ++ET +E P + QR L V + RF RN +GE I ++ L Sbjct: 194 KNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTF 253 Query: 472 -KKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQV 530 K L C G +GEL++SL Y P++ + + V Sbjct: 254 WKDLKPCSDGSGS------------RGELLLSLCYNPSANSII----------------V 285 Query: 531 WIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLE 590 I +A+NL A GGTSD +VK +L+ + K+KT MK+ LNP +N +F ++ + E Sbjct: 286 NIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFD-IPTE 344 Query: 591 DLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDWMDSTG---EEVSLWQKMR 647 L+ + +TV D++ L+ ND +G + L +G GEV W D + V+ W +++ Sbjct: 345 KLRETTIIITVMDKDKLSRNDVIGKIYLSWKSG--PGEVKHWKDMIARPRQPVAQWHQLK 402 >gi|238550198 synaptotagmin III [Homo sapiens] Length = 590 Score = 130 bits (326), Expect = 5e-30 Identities = 94/284 (33%), Positives = 142/284 (50%), Gaps = 48/284 (16%) Query: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407 +G+ G GRI+F+L+Y + LVV + + L A ++ S+PYVK YLLPD+ + Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK 349 Query: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467 K +T + R T+NP+++ET ++ +P + LAQR L FSV+ RF R+ +G+ Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV------ 401 Query: 468 WKLDKKLDHCLPLHGKISAESPTGLP------------SHKGELVVSLKYIPASKTPVGG 515 LD+ L L AE P P + GEL SL Y+P + Sbjct: 402 -----VLDNLLEL-----AEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTA------ 445 Query: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575 G L V I +A NL A G SD +VK L+ + KRKT + K TLN Sbjct: 446 ----------GRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLN 495 Query: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619 P YN V++ V E ++++ L + V D + + N+ +G R+G Sbjct: 496 PTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 1/110 (0%) Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 G + FSL Y L V + + L D S+PYVK L+ + R KRKTSIK+ Sbjct: 433 GELNFSLCYLPTAGRLTVTIIKASNLKAMD-LTGFSDPYVKASLISEGRRLKKRKTSIKK 491 Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467 +T+NP Y+E L +++ + L +V + G N +G + D+ Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541 >gi|238550196 synaptotagmin III [Homo sapiens] Length = 590 Score = 130 bits (326), Expect = 5e-30 Identities = 94/284 (33%), Positives = 142/284 (50%), Gaps = 48/284 (16%) Query: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407 +G+ G GRI+F+L+Y + LVV + + L A ++ S+PYVK YLLPD+ + Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK 349 Query: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467 K +T + R T+NP+++ET ++ +P + LAQR L FSV+ RF R+ +G+ Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV------ 401 Query: 468 WKLDKKLDHCLPLHGKISAESPTGLP------------SHKGELVVSLKYIPASKTPVGG 515 LD+ L L AE P P + GEL SL Y+P + Sbjct: 402 -----VLDNLLEL-----AEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTA------ 445 Query: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575 G L V I +A NL A G SD +VK L+ + KRKT + K TLN Sbjct: 446 ----------GRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLN 495 Query: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619 P YN V++ V E ++++ L + V D + + N+ +G R+G Sbjct: 496 PTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 1/110 (0%) Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 G + FSL Y L V + + L D S+PYVK L+ + R KRKTSIK+ Sbjct: 433 GELNFSLCYLPTAGRLTVTIIKASNLKAMD-LTGFSDPYVKASLISEGRRLKKRKTSIKK 491 Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467 +T+NP Y+E L +++ + L +V + G N +G + D+ Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541 >gi|14150054 synaptotagmin III [Homo sapiens] Length = 590 Score = 130 bits (326), Expect = 5e-30 Identities = 94/284 (33%), Positives = 142/284 (50%), Gaps = 48/284 (16%) Query: 348 AGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSR 407 +G+ G GRI+F+L+Y + LVV + + L A ++ S+PYVK YLLPD+ + Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLP-AKDSNGFSDPYVKIYLLPDRKK 349 Query: 408 QGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467 K +T + R T+NP+++ET ++ +P + LAQR L FSV+ RF R+ +G+ Sbjct: 350 --KFQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQV------ 401 Query: 468 WKLDKKLDHCLPLHGKISAESPTGLP------------SHKGELVVSLKYIPASKTPVGG 515 LD+ L L AE P P + GEL SL Y+P + Sbjct: 402 -----VLDNLLEL-----AEQPPDRPLWRDIVEGGSEKADLGELNFSLCYLPTA------ 445 Query: 516 DRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLN 575 G L V I +A NL A G SD +VK L+ + KRKT + K TLN Sbjct: 446 ----------GRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKRKTSIKKNTLN 495 Query: 576 PHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG 619 P YN V++ V E ++++ L + V D + + N+ +G R+G Sbjct: 496 PTYNEALVFD-VAPESVENVGLSIAVVDYDCIGHNEVIGVCRVG 538 Score = 55.8 bits (133), Expect = 1e-07 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 1/110 (0%) Query: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417 G + FSL Y L V + + L D S+PYVK L+ + R KRKTSIK+ Sbjct: 433 GELNFSLCYLPTAGRLTVTIIKASNLKAMD-LTGFSDPYVKASLISEGRRLKKRKTSIKK 491 Query: 418 DTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLGEAEIQMDS 467 +T+NP Y+E L +++ + L +V + G N +G + D+ Sbjct: 492 NTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDA 541 >gi|39752671 synaptotagmin X [Homo sapiens] Length = 523 Score = 125 bits (314), Expect = 1e-28 Identities = 89/331 (26%), Positives = 162/331 (48%), Gaps = 32/331 (9%) Query: 329 MQSGSSMSTIGSMM-------SIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECH 381 +Q G + ++IG + S+ SE ++ + G++ F+L+Y+ + + LVV + + Sbjct: 197 LQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKAL 256 Query: 382 QLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRT 441 L A + S+PYVK YLLPD+ + K +T + R T+NPL+DET ++ + L+ R Sbjct: 257 DLP-AKDFTGTSDPYVKMYLLPDRKK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRK 313 Query: 442 LQFSVWHHGRFGRNTFLGEAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPSHKGELVV 501 L FSV+ RF R+ +G E+ +D+ L + I + + GE++ Sbjct: 314 LHFSVYDFDRFSRHDMIG--EVILDNLFEVSDLSREATVWKDIHCATTESI--DLGEIMF 369 Query: 502 SLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNK 561 SL Y+P + G + + + + +NL A G+SD +VK L+ + Sbjct: 370 SLCYLPTA----------------GRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRR 413 Query: 562 ASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGV- 620 KRKT K TLNP YN +++ + E++ + L + V D + + N+ +G R G+ Sbjct: 414 LKKRKTTTKKNTLNPVYNEAIIFD-IPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLD 472 Query: 621 GTGISNGEVVDWMDSTGEEVSLWQKMRQYPG 651 G+ + + + ++ W + + PG Sbjct: 473 AEGLGRDHWNEMLAYHRKPITHWHPLLELPG 503 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.131 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,983,415 Number of Sequences: 37866 Number of extensions: 1233245 Number of successful extensions: 4990 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 95 Number of HSP's successfully gapped in prelim test: 114 Number of HSP's that attempted gapping in prelim test: 4296 Number of HSP's gapped (non-prelim): 515 length of query: 671 length of database: 18,247,518 effective HSP length: 109 effective length of query: 562 effective length of database: 14,120,124 effective search space: 7935509688 effective search space used: 7935509688 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.