BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|193794830 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 10 [Homo sapiens] (2155 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|193794830 calcium channel, voltage-dependent, L type, alpha 1... 4313 0.0 gi|193788724 calcium channel, voltage-dependent, L type, alpha 1... 4292 0.0 gi|193788732 calcium channel, voltage-dependent, L type, alpha 1... 4288 0.0 gi|193788720 calcium channel, voltage-dependent, L type, alpha 1... 4274 0.0 gi|193788538 calcium channel, voltage-dependent, L type, alpha 1... 4241 0.0 gi|193788548 calcium channel, voltage-dependent, L type, alpha 1... 4226 0.0 gi|193788540 calcium channel, voltage-dependent, L type, alpha 1... 4225 0.0 gi|193788542 calcium channel, voltage-dependent, L type, alpha 1... 4221 0.0 gi|193788534 calcium channel, voltage-dependent, L type, alpha 1... 4215 0.0 gi|193794828 calcium channel, voltage-dependent, L type, alpha 1... 4213 0.0 gi|193788544 calcium channel, voltage-dependent, L type, alpha 1... 4213 0.0 gi|193788530 calcium channel, voltage-dependent, L type, alpha 1... 4209 0.0 gi|193788526 calcium channel, voltage-dependent, L type, alpha 1... 4209 0.0 gi|120433602 calcium channel, voltage-dependent, L type, alpha 1... 4205 0.0 gi|193788730 calcium channel, voltage-dependent, L type, alpha 1... 4203 0.0 gi|193788536 calcium channel, voltage-dependent, L type, alpha 1... 4203 0.0 gi|193788532 calcium channel, voltage-dependent, L type, alpha 1... 4199 0.0 gi|193788728 calcium channel, voltage-dependent, L type, alpha 1... 4194 0.0 gi|193788528 calcium channel, voltage-dependent, L type, alpha 1... 4194 0.0 gi|193794832 calcium channel, voltage-dependent, L type, alpha 1... 4190 0.0 gi|192807298 calcium channel, voltage-dependent, L type, alpha 1... 2741 0.0 gi|192807300 calcium channel, voltage-dependent, L type, alpha 1... 2739 0.0 gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D ... 2739 0.0 gi|110349767 calcium channel, voltage-dependent, L type, alpha 1... 2299 0.0 gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F... 2271 0.0 gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s... 764 0.0 gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 759 0.0 gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s... 756 0.0 gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E... 736 0.0 gi|111378393 sodium channel, voltage-gated, type VII, alpha [Hom... 404 e-112 >gi|193794830 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 10 [Homo sapiens] Length = 2155 Score = 4313 bits (11185), Expect = 0.0 Identities = 2155/2155 (100%), Positives = 2155/2155 (100%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 Query: 1321 GSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1380 GSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV Sbjct: 1321 GSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1380 Query: 1381 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1440 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML Sbjct: 1381 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1440 Query: 1441 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT 1500 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT Sbjct: 1441 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT 1500 Query: 1501 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL 1560 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL Sbjct: 1501 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL 1560 Query: 1561 VSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQ 1620 VSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQ Sbjct: 1561 VSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQ 1620 Query: 1621 VVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGP 1680 VVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGP Sbjct: 1621 VVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGP 1680 Query: 1681 EIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFT 1740 EIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFT Sbjct: 1681 EIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFT 1740 Query: 1741 TQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAG 1800 TQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAG Sbjct: 1741 TQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAG 1800 Query: 1801 YPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNH 1860 YPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNH Sbjct: 1801 YPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNH 1860 Query: 1861 DTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLEC 1920 DTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLEC Sbjct: 1861 DTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLEC 1920 Query: 1921 LKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRG 1980 LKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRG Sbjct: 1921 LKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRG 1980 Query: 1981 WPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAG 2040 WPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAG Sbjct: 1981 WPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAG 2040 Query: 2041 APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILS 2100 APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILS Sbjct: 2041 APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILS 2100 Query: 2101 GGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 GGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 GGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 >gi|193788724 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 2 [Homo sapiens] Length = 2186 Score = 4292 bits (11132), Expect = 0.0 Identities = 2155/2186 (98%), Positives = 2155/2186 (98%), Gaps = 31/2186 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNH--------------------ILGNADYVF 940 IFTNLILFFILLSSISLAAEDPVQHTSFRNH ILGNADYVF Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 941 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1300 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1320 Query: 1301 SETNHYFCDAWNTFDALIVVGSIVDIAITEVN-----------NAEENSRISITFFRLFR 1349 SETNHYFCDAWNTFDALIVVGSIVDIAITEVN NAEENSRISITFFRLFR Sbjct: 1321 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1380 Query: 1350 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1409 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE Sbjct: 1381 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1440 Query: 1410 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1469 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA Sbjct: 1441 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1500 Query: 1470 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1529 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI Sbjct: 1501 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1560 Query: 1530 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1589 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI Sbjct: 1561 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1620 Query: 1590 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1649 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK Sbjct: 1621 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1680 Query: 1650 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1709 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE Sbjct: 1681 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1740 Query: 1710 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1769 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST Sbjct: 1741 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1800 Query: 1770 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1829 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS Sbjct: 1801 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1860 Query: 1830 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP 1889 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP Sbjct: 1861 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP 1920 Query: 1890 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV 1949 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV Sbjct: 1921 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV 1980 Query: 1950 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC 2009 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC Sbjct: 1981 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC 2040 Query: 2010 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD 2069 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD Sbjct: 2041 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD 2100 Query: 2070 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE 2129 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE Sbjct: 2101 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE 2160 Query: 2130 DAGCVRARGRPSEEELQDSRVYVSSL 2155 DAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2161 DAGCVRARGRPSEEELQDSRVYVSSL 2186 >gi|193788732 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 5 [Homo sapiens] Length = 2166 Score = 4288 bits (11122), Expect = 0.0 Identities = 2148/2166 (99%), Positives = 2150/2166 (99%), Gaps = 11/2166 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 Query: 1321 GSIVDIAITEVN-----------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1369 GSIVDIAITEVN NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT Sbjct: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380 Query: 1370 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1429 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC Sbjct: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440 Query: 1430 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1489 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV Sbjct: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500 Query: 1490 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1549 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK Sbjct: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560 Query: 1550 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1609 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI Sbjct: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620 Query: 1610 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1669 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ Sbjct: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680 Query: 1670 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1729 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS Sbjct: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740 Query: 1730 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1789 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN Sbjct: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800 Query: 1790 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1849 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS Sbjct: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860 Query: 1850 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1909 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS Sbjct: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920 Query: 1910 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1969 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF Sbjct: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980 Query: 1970 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2029 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR Sbjct: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040 Query: 2030 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2089 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE Sbjct: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100 Query: 2090 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2149 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR Sbjct: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160 Query: 2150 VYVSSL 2155 VYVSSL Sbjct: 2161 VYVSSL 2166 >gi|193788720 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 1 [Homo sapiens] Length = 2221 Score = 4274 bits (11086), Expect = 0.0 Identities = 2155/2221 (97%), Positives = 2155/2221 (97%), Gaps = 66/2221 (2%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNH--------------------ILGNADYVF 940 IFTNLILFFILLSSISLAAEDPVQHTSFRNH ILGNADYVF Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 941 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1300 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1320 Query: 1301 SETNHYFCDAWNTFDALIVVGSIVDIAITEVN-----------NAEENSRISITFFRLFR 1349 SETNHYFCDAWNTFDALIVVGSIVDIAITEVN NAEENSRISITFFRLFR Sbjct: 1321 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1380 Query: 1350 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1409 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE Sbjct: 1381 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1440 Query: 1410 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1469 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA Sbjct: 1441 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1500 Query: 1470 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1529 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI Sbjct: 1501 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1560 Query: 1530 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1589 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI Sbjct: 1561 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1620 Query: 1590 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1649 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK Sbjct: 1621 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1680 Query: 1650 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1709 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE Sbjct: 1681 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1740 Query: 1710 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1769 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST Sbjct: 1741 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1800 Query: 1770 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1829 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS Sbjct: 1801 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1860 Query: 1830 SN-----------------------------------RCHSRESQAAMAGQEETSQDETY 1854 SN RCHSRESQAAMAGQEETSQDETY Sbjct: 1861 SNRERHVPMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETY 1920 Query: 1855 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA 1914 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA Sbjct: 1921 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA 1980 Query: 1915 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA 1974 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA Sbjct: 1981 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA 2040 Query: 1975 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM 2034 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM Sbjct: 2041 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM 2100 Query: 2035 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA 2094 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA Sbjct: 2101 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA 2160 Query: 2095 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS 2154 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS Sbjct: 2161 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS 2220 Query: 2155 L 2155 L Sbjct: 2221 L 2221 >gi|193788538 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 15 [Homo sapiens] Length = 2138 Score = 4241 bits (10998), Expect = 0.0 Identities = 2129/2158 (98%), Positives = 2130/2158 (98%), Gaps = 23/2158 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN H C Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQC--------- 1311 Query: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1312 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 Query: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 Query: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 Query: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 Query: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1617 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL Sbjct: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1600 Query: 1618 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1677 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD Sbjct: 1601 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1660 Query: 1678 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1737 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ Sbjct: 1661 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1720 Query: 1738 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1797 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR Sbjct: 1721 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1780 Query: 1798 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1857 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK Sbjct: 1781 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1840 Query: 1858 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1917 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH Sbjct: 1841 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1900 Query: 1918 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1977 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG Sbjct: 1901 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1960 Query: 1978 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2037 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS Sbjct: 1961 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2020 Query: 2038 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2097 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN Sbjct: 2021 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2080 Query: 2098 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2081 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788548 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 20 [Homo sapiens] Length = 2127 Score = 4226 bits (10961), Expect = 0.0 Identities = 2120/2155 (98%), Positives = 2122/2155 (98%), Gaps = 28/2155 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+ Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIV------------------------ 1296 Query: 1321 GSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1380 DIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV Sbjct: 1297 ----DIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1352 Query: 1381 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1440 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML Sbjct: 1353 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1412 Query: 1441 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT 1500 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT Sbjct: 1413 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT 1472 Query: 1501 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL 1560 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL Sbjct: 1473 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL 1532 Query: 1561 VSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQ 1620 VSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQ Sbjct: 1533 VSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQ 1592 Query: 1621 VVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGP 1680 VVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGP Sbjct: 1593 VVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGP 1652 Query: 1681 EIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFT 1740 EIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFT Sbjct: 1653 EIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFT 1712 Query: 1741 TQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAG 1800 TQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAG Sbjct: 1713 TQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAG 1772 Query: 1801 YPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNH 1860 YPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNH Sbjct: 1773 YPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNH 1832 Query: 1861 DTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLEC 1920 DTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLEC Sbjct: 1833 DTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLEC 1892 Query: 1921 LKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRG 1980 LKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRG Sbjct: 1893 LKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRG 1952 Query: 1981 WPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAG 2040 WPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAG Sbjct: 1953 WPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAG 2012 Query: 2041 APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILS 2100 APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILS Sbjct: 2013 APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILS 2072 Query: 2101 GGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 GGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2073 GGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2127 >gi|193788540 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 16 [Homo sapiens] Length = 2138 Score = 4225 bits (10957), Expect = 0.0 Identities = 2122/2158 (98%), Positives = 2125/2158 (98%), Gaps = 23/2158 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN H C Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQC--------- 1311 Query: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1312 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 Query: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 Query: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 Query: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 Query: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1617 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL Sbjct: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1600 Query: 1618 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1677 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD Sbjct: 1601 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1660 Query: 1678 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1737 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ Sbjct: 1661 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1720 Query: 1738 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1797 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR Sbjct: 1721 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1780 Query: 1798 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1857 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK Sbjct: 1781 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1840 Query: 1858 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1917 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH Sbjct: 1841 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1900 Query: 1918 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1977 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG Sbjct: 1901 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1960 Query: 1978 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2037 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS Sbjct: 1961 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2020 Query: 2038 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2097 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN Sbjct: 2021 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2080 Query: 2098 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2081 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788542 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 17 [Homo sapiens] Length = 2138 Score = 4221 bits (10947), Expect = 0.0 Identities = 2117/2158 (98%), Positives = 2123/2158 (98%), Gaps = 23/2158 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E N H C Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQC--------- 1311 Query: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1312 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 Query: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 Query: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 Query: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 Query: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1617 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL Sbjct: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1600 Query: 1618 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1677 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD Sbjct: 1601 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1660 Query: 1678 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1737 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ Sbjct: 1661 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1720 Query: 1738 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1797 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR Sbjct: 1721 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1780 Query: 1798 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1857 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK Sbjct: 1781 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1840 Query: 1858 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1917 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH Sbjct: 1841 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1900 Query: 1918 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1977 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG Sbjct: 1901 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1960 Query: 1978 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2037 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS Sbjct: 1961 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2020 Query: 2038 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2097 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN Sbjct: 2021 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2080 Query: 2098 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2081 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788534 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 12 [Homo sapiens] Length = 2146 Score = 4215 bits (10931), Expect = 0.0 Identities = 2120/2174 (97%), Positives = 2122/2174 (97%), Gaps = 47/2174 (2%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+ Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIV------------------------ 1296 Query: 1321 GSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1380 DIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV Sbjct: 1297 ----DIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1352 Query: 1381 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1440 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML Sbjct: 1353 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1412 Query: 1441 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT 1500 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT Sbjct: 1413 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT 1472 Query: 1501 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL 1560 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL Sbjct: 1473 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL 1532 Query: 1561 VSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLEQANEE 1601 VSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLEQANEE Sbjct: 1533 VSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEE 1592 Query: 1602 LRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPS 1661 LRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPS Sbjct: 1593 LRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPS 1652 Query: 1662 QRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFG 1721 QRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFG Sbjct: 1653 QRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFG 1712 Query: 1722 NHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSN 1781 NHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSN Sbjct: 1713 NHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSN 1772 Query: 1782 ANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA 1841 ANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA Sbjct: 1773 ANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA 1832 Query: 1842 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPK 1901 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPK Sbjct: 1833 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPK 1892 Query: 1902 RGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHS 1961 RGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHS Sbjct: 1893 RGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHS 1952 Query: 1962 PASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGG 2021 PASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGG Sbjct: 1953 PASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGG 2012 Query: 2022 SSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELA 2081 SSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELA Sbjct: 2013 SSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELA 2072 Query: 2082 DACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPS 2141 DACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPS Sbjct: 2073 DACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPS 2132 Query: 2142 EEELQDSRVYVSSL 2155 EEELQDSRVYVSSL Sbjct: 2133 EEELQDSRVYVSSL 2146 >gi|193794828 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 7 [Homo sapiens] Length = 2157 Score = 4213 bits (10927), Expect = 0.0 Identities = 2122/2177 (97%), Positives = 2125/2177 (97%), Gaps = 42/2177 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN H C Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQC--------- 1311 Query: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1312 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 Query: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 Query: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 Query: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 Query: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLEQA 1598 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLEQA Sbjct: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQA 1600 Query: 1599 NEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG 1658 NEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG Sbjct: 1601 NEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG 1660 Query: 1659 KPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG 1718 KPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG Sbjct: 1661 KPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG 1720 Query: 1719 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSST 1778 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSST Sbjct: 1721 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSST 1780 Query: 1779 GSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRES 1838 GSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRES Sbjct: 1781 GSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRES 1840 Query: 1839 QAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQ 1898 QAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQ Sbjct: 1841 QAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQ 1900 Query: 1899 SPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQR 1958 SPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQR Sbjct: 1901 SPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQR 1960 Query: 1959 SHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPG 2018 SHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPG Sbjct: 1961 SHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPG 2020 Query: 2019 GGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQ 2078 GGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQ Sbjct: 2021 GGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQ 2080 Query: 2079 ELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARG 2138 ELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARG Sbjct: 2081 ELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARG 2140 Query: 2139 RPSEEELQDSRVYVSSL 2155 RPSEEELQDSRVYVSSL Sbjct: 2141 RPSEEELQDSRVYVSSL 2157 >gi|193788544 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 19 [Homo sapiens] Length = 2135 Score = 4213 bits (10926), Expect = 0.0 Identities = 2119/2158 (98%), Positives = 2122/2158 (98%), Gaps = 26/2158 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIA AEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIA---AEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 357 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 358 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 417 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 418 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 477 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 478 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 537 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 538 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 597 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 598 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 657 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 658 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 717 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 718 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 777 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 778 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 837 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 838 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 897 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 898 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 957 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 958 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1017 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1018 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1077 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1078 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1137 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1138 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1197 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1198 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1257 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN H C Sbjct: 1258 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQC--------- 1308 Query: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1309 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1357 Query: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1358 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1417 Query: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1418 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1477 Query: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1478 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1537 Query: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1617 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL Sbjct: 1538 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1597 Query: 1618 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1677 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD Sbjct: 1598 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1657 Query: 1678 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1737 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ Sbjct: 1658 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1717 Query: 1738 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1797 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR Sbjct: 1718 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1777 Query: 1798 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1857 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK Sbjct: 1778 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1837 Query: 1858 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1917 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH Sbjct: 1838 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1897 Query: 1918 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1977 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG Sbjct: 1898 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1957 Query: 1978 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2037 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS Sbjct: 1958 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2017 Query: 2038 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2097 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN Sbjct: 2018 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2077 Query: 2098 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2078 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2135 >gi|193788530 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 9 [Homo sapiens] Length = 2157 Score = 4209 bits (10917), Expect = 0.0 Identities = 2117/2177 (97%), Positives = 2123/2177 (97%), Gaps = 42/2177 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E N H C Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQC--------- 1311 Query: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1312 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 Query: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 Query: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 Query: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 Query: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLEQA 1598 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLEQA Sbjct: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQA 1600 Query: 1599 NEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG 1658 NEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG Sbjct: 1601 NEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG 1660 Query: 1659 KPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG 1718 KPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG Sbjct: 1661 KPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG 1720 Query: 1719 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSST 1778 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSST Sbjct: 1721 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSST 1780 Query: 1779 GSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRES 1838 GSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRES Sbjct: 1781 GSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRES 1840 Query: 1839 QAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQ 1898 QAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQ Sbjct: 1841 QAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQ 1900 Query: 1899 SPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQR 1958 SPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQR Sbjct: 1901 SPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQR 1960 Query: 1959 SHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPG 2018 SHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPG Sbjct: 1961 SHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPG 2020 Query: 2019 GGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQ 2078 GGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQ Sbjct: 2021 GGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQ 2080 Query: 2079 ELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARG 2138 ELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARG Sbjct: 2081 ELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARG 2140 Query: 2139 RPSEEELQDSRVYVSSL 2155 RPSEEELQDSRVYVSSL Sbjct: 2141 RPSEEELQDSRVYVSSL 2157 >gi|193788526 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 6 [Homo sapiens] Length = 2158 Score = 4209 bits (10916), Expect = 0.0 Identities = 2117/2178 (97%), Positives = 2123/2178 (97%), Gaps = 43/2178 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNH--------------------ILGNADYVF 940 IFTNLILFFILLSSISLAAEDPVQHTSFRNH ILGNADYVF Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 941 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1300 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ + Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAI 1320 Query: 1301 SETN---HYFCDAWNTFDALIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLL 1357 +E N H C + NAEENSRISITFFRLFRVMRLVKLL Sbjct: 1321 TEVNPAEHTQC--------------------SPSMNAEENSRISITFFRLFRVMRLVKLL 1360 Query: 1358 SRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQ 1417 SRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQ Sbjct: 1361 SRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQ 1420 Query: 1418 TFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFY 1477 TFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFY Sbjct: 1421 TFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFY 1480 Query: 1478 MLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTL 1537 MLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTL Sbjct: 1481 MLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTL 1540 Query: 1538 LRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQ 1597 LRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQ Sbjct: 1541 LRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQ 1600 Query: 1598 ANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLV 1657 ANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLV Sbjct: 1601 ANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLV 1660 Query: 1658 GKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAG 1717 GKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAG Sbjct: 1661 GKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAG 1720 Query: 1718 GLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSS 1777 GLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSS Sbjct: 1721 GLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSS 1780 Query: 1778 TGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRE 1837 TGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRE Sbjct: 1781 TGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRE 1840 Query: 1838 SQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIR 1897 SQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIR Sbjct: 1841 SQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIR 1900 Query: 1898 QSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQ 1957 QSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQ Sbjct: 1901 QSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQ 1960 Query: 1958 RSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTP 2017 RSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTP Sbjct: 1961 RSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTP 2020 Query: 2018 GGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTT 2077 GGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTT Sbjct: 2021 GGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTT 2080 Query: 2078 QELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRAR 2137 QELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRAR Sbjct: 2081 QELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRAR 2140 Query: 2138 GRPSEEELQDSRVYVSSL 2155 GRPSEEELQDSRVYVSSL Sbjct: 2141 GRPSEEELQDSRVYVSSL 2158 >gi|120433602 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 18 [Homo sapiens] Length = 2138 Score = 4205 bits (10906), Expect = 0.0 Identities = 2110/2158 (97%), Positives = 2118/2158 (98%), Gaps = 23/2158 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E N H C Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQC--------- 1311 Query: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1312 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 Query: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 Query: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 Query: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 Query: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1617 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL Sbjct: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1600 Query: 1618 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1677 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD Sbjct: 1601 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1660 Query: 1678 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1737 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ Sbjct: 1661 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1720 Query: 1738 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1797 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR Sbjct: 1721 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1780 Query: 1798 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1857 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK Sbjct: 1781 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1840 Query: 1858 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1917 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH Sbjct: 1841 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1900 Query: 1918 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1977 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG Sbjct: 1901 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1960 Query: 1978 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2037 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS Sbjct: 1961 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2020 Query: 2038 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2097 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN Sbjct: 2021 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2080 Query: 2098 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2081 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788730 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 4 [Homo sapiens] Length = 2173 Score = 4203 bits (10901), Expect = 0.0 Identities = 2117/2193 (96%), Positives = 2123/2193 (96%), Gaps = 58/2193 (2%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E N H C Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQC--------- 1311 Query: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1312 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 Query: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 Query: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 Query: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 Query: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1617 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL Sbjct: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1600 Query: 1618 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1677 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD Sbjct: 1601 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1660 Query: 1678 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1737 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ Sbjct: 1661 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1720 Query: 1738 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1797 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR Sbjct: 1721 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1780 Query: 1798 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSN-------------------------- 1831 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSN Sbjct: 1781 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRERHVPMCEDLELRRDSGSAGTQAHC 1840 Query: 1832 ---------RCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDE 1882 RCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDE Sbjct: 1841 LLLRKANPSRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDE 1900 Query: 1883 NRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLV 1942 NRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLV Sbjct: 1901 NRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLV 1960 Query: 1943 HHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNS 2002 HHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNS Sbjct: 1961 HHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNS 2020 Query: 2003 SFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEG 2062 SFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEG Sbjct: 2021 SFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEG 2080 Query: 2063 LGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQ 2122 LGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQ Sbjct: 2081 LGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQ 2140 Query: 2123 DRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 DRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2141 DRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2173 >gi|193788536 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 14 [Homo sapiens] Length = 2138 Score = 4203 bits (10901), Expect = 0.0 Identities = 2107/2158 (97%), Positives = 2119/2158 (98%), Gaps = 23/2158 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYW+ DA+G + PW+YFV+L+I GSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E N H C Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQC--------- 1311 Query: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1312 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 Query: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 Query: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 Query: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 Query: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1617 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL Sbjct: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1600 Query: 1618 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1677 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD Sbjct: 1601 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1660 Query: 1678 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1737 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ Sbjct: 1661 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1720 Query: 1738 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1797 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR Sbjct: 1721 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1780 Query: 1798 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1857 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK Sbjct: 1781 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1840 Query: 1858 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1917 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH Sbjct: 1841 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1900 Query: 1918 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1977 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG Sbjct: 1901 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1960 Query: 1978 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2037 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS Sbjct: 1961 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2020 Query: 2038 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2097 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN Sbjct: 2021 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2080 Query: 2098 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2081 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788532 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 11 [Homo sapiens] Length = 2146 Score = 4199 bits (10890), Expect = 0.0 Identities = 2113/2174 (97%), Positives = 2117/2174 (97%), Gaps = 47/2174 (2%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+ Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIV------------------------ 1296 Query: 1321 GSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1380 DIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV Sbjct: 1297 ----DIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1352 Query: 1381 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1440 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML Sbjct: 1353 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1412 Query: 1441 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT 1500 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT Sbjct: 1413 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT 1472 Query: 1501 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL 1560 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL Sbjct: 1473 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL 1532 Query: 1561 VSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLEQANEE 1601 VSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLEQANEE Sbjct: 1533 VSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEE 1592 Query: 1602 LRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPS 1661 LRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPS Sbjct: 1593 LRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPS 1652 Query: 1662 QRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFG 1721 QRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFG Sbjct: 1653 QRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFG 1712 Query: 1722 NHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSN 1781 NHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSN Sbjct: 1713 NHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSN 1772 Query: 1782 ANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA 1841 ANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA Sbjct: 1773 ANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA 1832 Query: 1842 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPK 1901 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPK Sbjct: 1833 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPK 1892 Query: 1902 RGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHS 1961 RGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHS Sbjct: 1893 RGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHS 1952 Query: 1962 PASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGG 2021 PASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGG Sbjct: 1953 PASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGG 2012 Query: 2022 SSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELA 2081 SSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELA Sbjct: 2013 SSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELA 2072 Query: 2082 DACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPS 2141 DACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPS Sbjct: 2073 DACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPS 2132 Query: 2142 EEELQDSRVYVSSL 2155 EEELQDSRVYVSSL Sbjct: 2133 EEELQDSRVYVSSL 2146 >gi|193788728 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 3 [Homo sapiens] Length = 2179 Score = 4194 bits (10878), Expect = 0.0 Identities = 2112/2183 (96%), Positives = 2123/2183 (97%), Gaps = 32/2183 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFC------DAW 1311 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E N H C Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 Query: 1312 NTFDALIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFI 1371 + A++ + D NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFI Sbjct: 1321 HPPLAVLTAPPVAD----GFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFI 1376 Query: 1372 KSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCAT 1431 KSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCAT Sbjct: 1377 KSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCAT 1436 Query: 1432 GEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAV 1491 GEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAV Sbjct: 1437 GEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAV 1496 Query: 1492 IMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLC 1551 IMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLC Sbjct: 1497 IMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLC 1556 Query: 1552 PHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE------------------- 1592 PHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE Sbjct: 1557 PHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPA 1616 Query: 1593 GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRK 1652 GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRK Sbjct: 1617 GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRK 1676 Query: 1653 EQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDI 1712 EQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDI Sbjct: 1677 EQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDI 1736 Query: 1713 FRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTP 1772 FRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTP Sbjct: 1737 FRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTP 1796 Query: 1773 SSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNR 1832 SSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNR Sbjct: 1797 SSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNR 1856 Query: 1833 CHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEED 1892 CHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEED Sbjct: 1857 CHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEED 1916 Query: 1893 KRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGL 1952 KRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGL Sbjct: 1917 KRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGL 1976 Query: 1953 SPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSW 2012 SPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSW Sbjct: 1977 SPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSW 2036 Query: 2013 AETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKF 2072 AETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKF Sbjct: 2037 AETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKF 2096 Query: 2073 IEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAG 2132 IEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAG Sbjct: 2097 IEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAG 2156 Query: 2133 CVRARGRPSEEELQDSRVYVSSL 2155 CVRARGRPSEEELQDSRVYVSSL Sbjct: 2157 CVRARGRPSEEELQDSRVYVSSL 2179 >gi|193788528 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 8 [Homo sapiens] Length = 2157 Score = 4194 bits (10876), Expect = 0.0 Identities = 2110/2177 (96%), Positives = 2118/2177 (97%), Gaps = 42/2177 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E N H C Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQC--------- 1311 Query: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1312 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 Query: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 Query: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 Query: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 Query: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLEQA 1598 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLEQA Sbjct: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQA 1600 Query: 1599 NEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG 1658 NEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG Sbjct: 1601 NEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVG 1660 Query: 1659 KPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG 1718 KPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG Sbjct: 1661 KPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG 1720 Query: 1719 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSST 1778 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSST Sbjct: 1721 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSST 1780 Query: 1779 GSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRES 1838 GSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRES Sbjct: 1781 GSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRES 1840 Query: 1839 QAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQ 1898 QAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQ Sbjct: 1841 QAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQ 1900 Query: 1899 SPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQR 1958 SPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQR Sbjct: 1901 SPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQR 1960 Query: 1959 SHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPG 2018 SHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPG Sbjct: 1961 SHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPG 2020 Query: 2019 GGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQ 2078 GGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQ Sbjct: 2021 GGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQ 2080 Query: 2079 ELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARG 2138 ELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARG Sbjct: 2081 ELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARG 2140 Query: 2139 RPSEEELQDSRVYVSSL 2155 RPSEEELQDSRVYVSSL Sbjct: 2141 RPSEEELQDSRVYVSSL 2157 >gi|193794832 calcium channel, voltage-dependent, L type, alpha 1C subunit isoforom 13 [Homo sapiens] Length = 2144 Score = 4190 bits (10868), Expect = 0.0 Identities = 2112/2174 (97%), Positives = 2115/2174 (97%), Gaps = 49/2174 (2%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GS Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGS-------------------------- 1294 Query: 1321 GSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1380 IVDIAITE NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV Sbjct: 1295 --IVDIAITE--NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1350 Query: 1381 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1440 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML Sbjct: 1351 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1410 Query: 1441 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT 1500 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT Sbjct: 1411 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLT 1470 Query: 1501 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL 1560 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL Sbjct: 1471 RDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRL 1530 Query: 1561 VSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLEQANEE 1601 VSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLEQANEE Sbjct: 1531 VSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEE 1590 Query: 1602 LRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPS 1661 LRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPS Sbjct: 1591 LRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPS 1650 Query: 1662 QRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFG 1721 QRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFG Sbjct: 1651 QRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFG 1710 Query: 1722 NHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSN 1781 NHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSN Sbjct: 1711 NHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSN 1770 Query: 1782 ANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA 1841 ANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA Sbjct: 1771 ANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA 1830 Query: 1842 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPK 1901 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPK Sbjct: 1831 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPK 1890 Query: 1902 RGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHS 1961 RGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHS Sbjct: 1891 RGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHS 1950 Query: 1962 PASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGG 2021 PASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGG Sbjct: 1951 PASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGG 2010 Query: 2022 SSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELA 2081 SSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELA Sbjct: 2011 SSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELA 2070 Query: 2082 DACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPS 2141 DACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPS Sbjct: 2071 DACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPS 2130 Query: 2142 EEELQDSRVYVSSL 2155 EEELQDSRVYVSSL Sbjct: 2131 EEELQDSRVYVSSL 2144 >gi|192807298 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform c [Homo sapiens] Length = 2137 Score = 2741 bits (7105), Expect = 0.0 Identities = 1456/2173 (67%), Positives = 1660/2173 (76%), Gaps = 153/2173 (7%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYW+NDA+G + PW+YFV+L+I GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN--CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524 PTSETESVNTENV+G EGEN C L ISKSK SR WRRWNRF RR+CRAAVKS Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSV 523 Query: 525 VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584 FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LLALFT EML+KMYSLGLQAYF Sbjct: 524 TFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYF 583 Query: 585 VSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASL 644 VSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRLLRIFK+TR+W SLSNLVASL Sbjct: 584 VSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASL 643 Query: 645 LNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILT 704 LNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT+RSTFDNFPQ+LLTVFQILT Sbjct: 644 LNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILT 703 Query: 705 GEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764 GEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYILLNVFLAIAVDNLADAESL + Sbjct: 704 GEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNT 763 Query: 765 AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMD 824 AQKEE EEKERKK+AR S E K+ KP V + K+ +D Sbjct: 764 AQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD---------------NKVTID 806 Query: 825 DLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASA 879 D + E+EDK PYP E EE+E+EPE+P GPRPR +SEL++KEK P+PE SA Sbjct: 807 DYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSA 865 Query: 880 FFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYV 939 FFI S N R+ CH+++N IFTNLIL FI+LSS +LAAEDP++ SFRN ILG DY Sbjct: 866 FFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYA 925 Query: 940 FTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRV 999 FT+IFT+EI+LKMT +GAFLHKG+FCRNYFN+LD+LVV VSL+SFGIQSSAI+VVKILRV Sbjct: 926 FTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRV 985 Query: 1000 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS 1059 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Y C+ Sbjct: 986 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCT 1045 Query: 1060 DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE 1119 D +K EC+G +I YKDG+VD P+++ R W+NS F+FDNVL+AMMALFTVSTFEGWP Sbjct: 1046 DEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPA 1105 Query: 1120 LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN 1179 LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMNIFVGFVIVTFQEQGE+EYKN Sbjct: 1106 LLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKN 1165 Query: 1180 CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239 CELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ FEY+MFVLI+LNT+CLAMQ Sbjct: 1166 CELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQ 1225 Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVI 1299 HY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPKGYFSD WN FD LIVIGSIIDV Sbjct: 1226 HYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDV- 1284 Query: 1300 LSETNHYFCDAWNTFDALIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSR 1359 A++E +N+EE++RISITFFRLFRVMRLVKLLSR Sbjct: 1285 ---------------------------ALSEADNSEESNRISITFFRLFRVMRLVKLLSR 1317 Query: 1360 GEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTF 1419 GEGIRTLLWTFIKSFQALPYVALLI MLFFIYAVIGMQ+FGK+A+ D +INRNNNFQTF Sbjct: 1318 GEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTF 1377 Query: 1420 PQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYML 1479 PQAVLLLFRCATGEAWQ+IMLAC+PGK C PES+ + E CGS+FA+ YFISFYML Sbjct: 1378 PQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGE--EYTCGSNFAIVYFISFYML 1435 Query: 1480 CAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLR 1539 CAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDPEAKGRIKHLDVVTLLR Sbjct: 1436 CAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLR 1495 Query: 1540 RIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQAN 1599 RIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTVMFNATLFALVRTAL+IKTEGNLEQAN Sbjct: 1496 RIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQAN 1555 Query: 1600 EELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGK 1659 EELRA+IKKIWK+TSMKLLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKFKKRKEQGLVGK Sbjct: 1556 EELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGK 1615 Query: 1660 -PSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG 1718 P++ ++LQAGLRTLHDIGPEIRRAIS DL +E E EDD+F+R G Sbjct: 1616 YPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDE------PEETKREEEDDVFKRNGA 1669 Query: 1719 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG-SSQGDTESPSHEKLVDST-FTPSSYS 1776 L GNHV++ SD R + QT TT RPLH+ + DTE P +S +++ Sbjct: 1670 LLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHN 1729 Query: 1777 S------TGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1830 S T +NAN+NNAN + RP+ + GH S Sbjct: 1730 SIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHVSENGH-----------------HS 1772 Query: 1831 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTE---------ACSEPSLLSTEMLSYQDD 1881 + H RE Q + + S DE D E E S+E Y+DD Sbjct: 1773 SHKHDREPQRRSSVKRSDSGDEQLPTICREDPEIHGYFRDPHCLGEQEYFSSEE-CYEDD 1831 Query: 1882 -----------------------------ENRQLTLPEEDK---RDIRQSPKRGFL-RSA 1908 + Q L ++D D R+SP+R L + Sbjct: 1832 SSPTWSRQNYGYYSRYPGRNIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTP 1891 Query: 1909 SLGRRASFHLECLKRQKDR-----GGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPA 1963 + RR+SF+ ECL+RQ + +T LPLHL+ Q +AVAGL + +SP+ Sbjct: 1892 ASHRRSSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPS 1951 Query: 1964 SFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSS 2023 R +ATPPATP R W P P +++E E+ +++N S PS+H SW P Sbjct: 1952 HSTRSWATPPATPPYRDWTPCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTDEP----DI 2007 Query: 2024 AARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADA 2083 + R P SL VPS SA SLVEAVLISEGLG++A+DPKF+ T E+ADA Sbjct: 2008 SYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADA 2067 Query: 2084 CDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAG-QDRAGGEEDAGCVRARGRPSE 2142 CD+TI+EMESAA +L+G NG + P + +D QD G D R E Sbjct: 2068 CDLTIDEMESAASTLLNGNVRPRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGR---DE 2124 Query: 2143 EELQDSRVYVSSL 2155 E+L D + +++L Sbjct: 2125 EDLADEMICITTL 2137 >gi|192807300 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform b [Homo sapiens] Length = 2161 Score = 2739 bits (7099), Expect = 0.0 Identities = 1456/2170 (67%), Positives = 1663/2170 (76%), Gaps = 123/2170 (5%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYW+NDA+G + PW+YFV+L+I GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN--CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524 PTSETESVNTENV+G EGEN C L ISKSK SR WRRWNRF RR+CRAAVKS Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSV 523 Query: 525 VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584 FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LLALFT EML+KMYSLGLQAYF Sbjct: 524 TFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYF 583 Query: 585 VSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASL 644 VSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRLLRIFK+TR+W SLSNLVASL Sbjct: 584 VSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASL 643 Query: 645 LNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILT 704 LNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT+RSTFDNFPQ+LLTVFQILT Sbjct: 644 LNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILT 703 Query: 705 GEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764 GEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYILLNVFLAIAVDNLADAESL + Sbjct: 704 GEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNT 763 Query: 765 AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMD 824 AQKEE EEKERKK+AR S E K+ KP V + K+ +D Sbjct: 764 AQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD---------------NKVTID 806 Query: 825 DLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASA 879 D + E+EDK PYP E EE+E+EPE+P GPRPR +SEL++KEK P+PE SA Sbjct: 807 DYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSA 865 Query: 880 FFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYV 939 FFI S N R+ CH+++N IFTNLIL FI+LSS +LAAEDP++ SFRN ILG DY Sbjct: 866 FFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYA 925 Query: 940 FTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRV 999 FT+IFT+EI+LKMT +GAFLHKG+FCRNYFN+LD+LVV VSL+SFGIQSSAI+VVKILRV Sbjct: 926 FTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRV 985 Query: 1000 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS 1059 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Y C+ Sbjct: 986 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCT 1045 Query: 1060 DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE 1119 D +K EC+G +I YKDG+VD P+++ R W+NS F+FDNVL+AMMALFTVSTFEGWP Sbjct: 1046 DEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPA 1105 Query: 1120 LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN 1179 LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMNIFVGFVIVTFQEQGE+EYKN Sbjct: 1106 LLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKN 1165 Query: 1180 CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239 CELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ FEY+MFVLI+LNT+CLAMQ Sbjct: 1166 CELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQ 1225 Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVI 1299 HY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPKGYFSD WN FD LIVIGSIIDV Sbjct: 1226 HYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVA 1285 Query: 1300 LSETNHYFCDAWNTFDALIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSR 1359 LSE + V + N+EE++RISITFFRLFRVMRLVKLLSR Sbjct: 1286 LSEADP-------------TESENVPVPTATPGNSEESNRISITFFRLFRVMRLVKLLSR 1332 Query: 1360 GEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTF 1419 GEGIRTLLWTFIKSFQALPYVALLI MLFFIYAVIGMQ+FGK+A+ D +INRNNNFQTF Sbjct: 1333 GEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTF 1392 Query: 1420 PQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYML 1479 PQAVLLLFRCATGEAWQ+IMLAC+PGK C PES+ + E CGS+FA+ YFISFYML Sbjct: 1393 PQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGE--EYTCGSNFAIVYFISFYML 1450 Query: 1480 CAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLR 1539 CAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDPEAKGRIKHLDVVTLLR Sbjct: 1451 CAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLR 1510 Query: 1540 RIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQAN 1599 RIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTVMFNATLFALVRTAL+IKTEGNLEQAN Sbjct: 1511 RIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQAN 1570 Query: 1600 EELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGK 1659 EELRA+IKKIWK+TSMKLLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKFKKRKEQGLVGK Sbjct: 1571 EELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGK 1630 Query: 1660 -PSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGG 1718 P++ ++LQAGLRTLHDIGPEIRRAIS DL +E E EDD+F+R G Sbjct: 1631 YPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDE------PEETKREEEDDVFKRNGA 1684 Query: 1719 LFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG-SSQGDTESPSHEKLVDST-FTPSSYS 1776 L GNHV++ SD R + QT TT RPLH+ + DTE P +S +++ Sbjct: 1685 LLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHN 1744 Query: 1777 S------TGSNANINNANNTALGRLPRPA----GYPSTVSTVEGHGPPLSPAIR--VQEV 1824 S T +NAN+NNAN + RP+ + S H P R V+ Sbjct: 1745 SIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHVSENGHHSSHKHDREPQRRSSVKRT 1804 Query: 1825 AWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDD--- 1881 + + R S + Q +E+ + D E S+E Y+DD Sbjct: 1805 RYYETYIRSDSGDEQLPTICREDPEIHGYF-----RDPHCLGEQEYFSSEE-CYEDDSSP 1858 Query: 1882 --------------------------ENRQLTLPEEDK---RDIRQSPKRGFL-RSASLG 1911 + Q L ++D D R+SP+R L + + Sbjct: 1859 TWSRQNYGYYSRYPGRNIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPASH 1918 Query: 1912 RRASFHLECLKRQKDR-----GGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFP 1966 RR+SF+ ECL+RQ + +T LPLHL+ Q +AVAGL + +SP+ Sbjct: 1919 RRSSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHST 1978 Query: 1967 RPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAAR 2026 R +ATPPATP R W P P +++E E+ +++N S PS+H SW P + R Sbjct: 1979 RSWATPPATPPYRDWTPCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTDEP----DISYR 2034 Query: 2027 RVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDM 2086 P SL VPS SA SLVEAVLISEGLG++A+DPKF+ T E+ADACD+ Sbjct: 2035 TFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDL 2094 Query: 2087 TIEEMESAADNILSGGAPQSPNGALLPFVNCRDAG-QDRAGGEEDAGCVRARGRPSEEEL 2145 TI+EMESAA +L+G NG + P + +D QD G D R EE+L Sbjct: 2095 TIDEMESAASTLLNGNVRPRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGR---DEEDL 2151 Query: 2146 QDSRVYVSSL 2155 D + +++L Sbjct: 2152 ADEMICITTL 2161 >gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform a [Homo sapiens] Length = 2181 Score = 2739 bits (7099), Expect = 0.0 Identities = 1460/2190 (66%), Positives = 1667/2190 (76%), Gaps = 143/2190 (6%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYWVNDA+G +WPW+YFV+LII+GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN---CGA-------------------RLAHRISKSKFSR 504 PTSETESVNTENV+G EGEN CG+ R ISKSK SR Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLWCWWRRRGAAKAGPSGCRRWGQAISKSKLSR 523 Query: 505 YWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALL 564 WRRWNRF RR+CRAAVKS FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LL Sbjct: 524 RWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLL 583 Query: 565 ALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRL 624 ALFT EML+KMYSLGLQAYFVSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRL Sbjct: 584 ALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRL 643 Query: 625 LRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQT 684 LRIFK+TR+W SLSNLVASLLNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT Sbjct: 644 LRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQT 703 Query: 685 RRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYIL 744 +RSTFDNFPQ+LLTVFQILTGEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYIL Sbjct: 704 KRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYIL 763 Query: 745 LNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKI 804 LNVFLAIAVDNLADAESL +AQKEE EEKERKK+AR S E K+ KP V + Sbjct: 764 LNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD- 820 Query: 805 ELKSITADGESPPATKINMDDLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRP 859 K+ +DD + E+EDK PYP E EE+E+EPE+P GPRP Sbjct: 821 --------------NKVTIDDYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRP 865 Query: 860 RPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAA 919 R +SEL++KEK P+PE SAFFI S N R+ CH+++N IFTNLIL FI+LSS +LAA Sbjct: 866 RRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAA 925 Query: 920 EDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSV 979 EDP++ SFRN ILG DY FT+IFT+EI+LKMT +GAFLHKG+FCRNYFN+LD+LVV V Sbjct: 926 EDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGV 985 Query: 980 SLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLL 1039 SL+SFGIQSSAI+VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLL Sbjct: 986 SLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLL 1045 Query: 1040 QFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFD 1099 QFMFACIGVQLFKGK Y C+D +K EC+G +I YKDG+VD P+++ R W+NS F+FD Sbjct: 1046 QFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFD 1105 Query: 1100 NVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMN 1159 NVL+AMMALFTVSTFEGWP LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMN Sbjct: 1106 NVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMN 1165 Query: 1160 IFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNST 1219 IFVGFVIVTFQEQGE+EYKNCELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ Sbjct: 1166 IFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSS 1225 Query: 1220 YFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYF 1279 FEY+MFVLI+LNT+CLAMQHY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPKGYF Sbjct: 1226 PFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYF 1285 Query: 1280 SDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNNAEENSR 1339 SD WN FD LIVIGSIIDV LSE + V + N+EE++R Sbjct: 1286 SDAWNTFDSLIVIGSIIDVALSEADP-------------TESENVPVPTATPGNSEESNR 1332 Query: 1340 ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF 1399 ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLI MLFFIYAVIGMQ+F Sbjct: 1333 ISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMF 1392 Query: 1400 GKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTE 1459 GK+A+ D +INRNNNFQTFPQAVLLLFRCATGEAWQ+IMLAC+PGK C PES+ + Sbjct: 1393 GKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGE- 1451 Query: 1460 GETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWA 1519 E CGS+FA+ YFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+ Sbjct: 1452 -EYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWS 1510 Query: 1520 EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATL 1579 EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTVMFNATL Sbjct: 1511 EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATL 1570 Query: 1580 FALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATF 1639 FALVRTAL+IKTEGNLEQANEELRA+IKKIWK+TSMKLLDQVVPPAGDDEVTVGKFYATF Sbjct: 1571 FALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATF 1630 Query: 1640 LIQEYFRKFKKRKEQGLVGK-PSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDK 1698 LIQ+YFRKFKKRKEQGLVGK P++ ++LQAGLRTLHDIGPEIRRAIS DL +E Sbjct: 1631 LIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDE---- 1686 Query: 1699 AMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG-SSQGDT 1757 E EDD+F+R G L GNHV++ SD R + QT TT RPLH+ + DT Sbjct: 1687 --PEETKREEEDDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDT 1744 Query: 1758 ESPSHEKLVDST-FTPSSYSS------TGSNANINNANNTALGRLPRPA----GYPSTVS 1806 E P +S +++S T +NAN+NNAN + RP+ + S Sbjct: 1745 EKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHVSENG 1804 Query: 1807 TVEGHGPPLSPAIR--VQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEA 1864 H P R V+ + + R S + Q +E+ + D Sbjct: 1805 HHSSHKHDREPQRRSSVKRTRYYETYIRSDSGDEQLPTICREDPEIHGYF-----RDPHC 1859 Query: 1865 CSEPSLLSTEMLSYQDD-----------------------------ENRQLTLPEEDK-- 1893 E S+E Y+DD + Q L ++D Sbjct: 1860 LGEQEYFSSEE-CYEDDSSPTWSRQNYGYYSRYPGRNIDSERPRGYHHPQGFLEDDDSPV 1918 Query: 1894 -RDIRQSPKRGFL-RSASLGRRASFHLECLKRQKDR-----GGDISQKTVLPLHLVHHQA 1946 D R+SP+R L + + RR+SF+ ECL+RQ + +T LPLHL+ Q Sbjct: 1919 CYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLMQQQI 1978 Query: 1947 LAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPS 2006 +AVAGL + +SP+ R +ATPPATP R W P P +++E E+ +++N S PS Sbjct: 1979 MAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQSEALDQVNGSLPS 2038 Query: 2007 IHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQF 2066 +H SW P + R P SL VPS SA SLVEAVLISEGLG++ Sbjct: 2039 LHRSSWYTDEP----DISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRY 2094 Query: 2067 AQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAG-QDRA 2125 A+DPKF+ T E+ADACD+TI+EMESAA +L+G NG + P + +D QD Sbjct: 2095 ARDPKFVSATKHEIADACDLTIDEMESAASTLLNGNVRPRANGDVGPLSHRQDYELQDFG 2154 Query: 2126 GGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 G D R EE+L D + +++L Sbjct: 2155 PGYSDEEPDPGR---DEEDLADEMICITTL 2181 >gi|110349767 calcium channel, voltage-dependent, L type, alpha 1S subunit [Homo sapiens] Length = 1873 Score = 2299 bits (5958), Expect = 0.0 Identities = 1177/1723 (68%), Positives = 1386/1723 (80%), Gaps = 61/1723 (3%) Query: 77 SSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFA 136 SS Q + + +PKK RPPRAL CLTL+NP+R+ACISIVEWKPFE IILLTIFA Sbjct: 4 SSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFA 63 Query: 137 NCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWN 196 NCVALA+Y+P PEDD+N+ N LE++EY FLI+F++EA +K+IAYG LFH +AYLR+GWN Sbjct: 64 NCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWN 123 Query: 197 LLDFIIVVVGLFSAILEQATKADGANA-LGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQ 255 +LDF IV +G+F+ ILEQ A + KGAG DVKALRAFRVLRPLRLVSGVPSLQ Sbjct: 124 VLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQ 183 Query: 256 VVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGIADVPAEDDP 313 VVLNSI KAM+PL HIALLVLF++IIYAIIGLELF GKMHKTCY + +A V E+ P Sbjct: 184 VVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEE-P 242 Query: 314 SPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWV 372 SPCA TG GR+C NG+ C+ GW GP HGIT+FDNF F+MLTV+QCITMEGWTDVLYWV Sbjct: 243 SPCA-RTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWV 301 Query: 373 NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEE 432 NDA+G +WPWIYFVTLI++GSFF+LNLVLGVLSGEF+KEREKAK+RG FQKLREKQQL+E Sbjct: 302 NDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDE 361 Query: 433 DLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGAR 492 DL+GY+ WITQ E +D E+ EG ++ S+TES+ +I G N Sbjct: 362 DLRGYMSWITQGEVMDVEDFREGK-----LSLDEGGSDTESLY-------EIAGLN---- 405 Query: 493 LAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWL 552 +F R+WR+WNR R KC VKS VFYWLVI +V LNTL+IASEH+NQP WL Sbjct: 406 -----KIIQFIRHWRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWL 460 Query: 553 TEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMS 612 T +QD AN+ LL+LFT EML+KMY LGL+ YF+S+FNRFDCFVVC GILE +LVE+ M+ Sbjct: 461 TRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMT 520 Query: 613 PLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQL 672 PLGISVLRC+RLLRIFKIT+YW SLSNLVASLLNS+RSIASLLLLLFLFI+IF+LLGMQL Sbjct: 521 PLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQL 580 Query: 673 FGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIY 732 FGG+++F++ + RRS FDNFPQ+L++VFQ+LTGEDW S+MY+GIMAYGGPS+PGMLVCIY Sbjct: 581 FGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIY 640 Query: 733 FIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVE 792 FIILF+CGNYILLNVFLAIAVDNLA+AESLTSAQK + EEK+R+K+++ P+K +E E Sbjct: 641 FIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEEKKRRKMSK-GLPDKSEE--E 697 Query: 793 KPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPE 852 K + + E+K + + I P K+ +D+ + N NE K PYP+ + G+++E+EPE Sbjct: 698 KSTMAKKLEQKPKGEGI------PTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPE 751 Query: 853 MPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILL 912 +P+ PRPRPL+EL LKEKAVP+PEAS+FFIFS N+ R+ CHRIVN T FTN IL FILL Sbjct: 752 IPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILL 811 Query: 913 SSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNIL 972 SS +LAAEDP++ S RN IL + D FTS+FT+EI+LKMT YGAFLHKGSFCRNYFN+L Sbjct: 812 SSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNML 871 Query: 973 DLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI 1032 DLLVV+VSLIS G++SSAI+VVKILRVLRVLRPLRAINRAKGLKHVVQC+FVAI TIGNI Sbjct: 872 DLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNI 931 Query: 1033 VIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWE 1092 V+VTTLLQFMFACIGVQLFKGK + C+D SK TE EC+G Y YKDG+ ++ R W Sbjct: 932 VLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWV 991 Query: 1093 NSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIII 1152 +S F FDNVL+AMM+LFTVSTFEGWP+LLY++IDS+ ED GPIYN RVE++IFFIIYII+ Sbjct: 992 HSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIIL 1051 Query: 1153 IAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKV 1212 IAFFMMNIFVGFVIVTFQEQGE EYKNCELDKNQRQCV+YALKARPLR YIPKN +QY+V Sbjct: 1052 IAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQV 1111 Query: 1213 WYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIA 1272 WY+V S+YFEYLMF LI+LNTICL MQHY QS +ILN+ FT +FT+EMILKL+A Sbjct: 1112 WYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMA 1171 Query: 1273 FKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVN 1332 FK +GYF DPWNVFDFLIVIGSIIDVILSE + + + + G++ Sbjct: 1172 FKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNV--------- 1222 Query: 1333 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYA 1392 + +E++RIS FFRLFRVMRL+KLLSR EG+RTLLWTFIKSFQALPYVALLIVMLFFIYA Sbjct: 1223 DPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYA 1282 Query: 1393 VIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPES 1452 VIGMQ+FGKIAL D T+INRNNNFQTFPQAVLLLFRCATGEAWQ+I+LAC GK C PES Sbjct: 1283 VIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPES 1342 Query: 1453 EPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLD 1512 + + E CG++FA +YFISFYMLCAFL+INLFVAVIMDNFDYLTRDWSILGPHHLD Sbjct: 1343 DYAPGE--EYTCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSILGPHHLD 1400 Query: 1513 EFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGT 1572 EFK IWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK CPHRVACKRLV MNMPLNSDGT Sbjct: 1401 EFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGT 1460 Query: 1573 VMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTV 1632 V FNATLFALVRTAL+IKTEGN EQANEELRAIIKKIWKRTSMKLLDQV+PP GDDEVTV Sbjct: 1461 VTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTV 1520 Query: 1633 GKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTL-HDIGPEIRRAISGDLT 1691 GKFYATFLIQE+FRKF KR+E+ G +++ + +QAGLRT+ + PEI R +SGDL Sbjct: 1521 GKFYATFLIQEHFRKFMKRQEE-YYGYRPKKDIVQIQAGLRTIEEEAAPEICRTVSGDLA 1579 Query: 1692 AEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG 1751 AEEEL++AM V AA E+ IFRR GGLFG ++ + ++ P QRPL A Sbjct: 1580 AEEELERAM---VEAAMEEGIFRRTGGLFGQVDNFLER--TNSLPPVMANQRPLQF--AE 1632 Query: 1752 SSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN-NTALG 1793 + ESP + F ++ + AN NNAN N A G Sbjct: 1633 IEMEEMESP----VFLEDFPQDPRTNPLARANTNNANANVAYG 1671 Score = 49.7 bits (117), Expect = 3e-05 Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 24/151 (15%) Query: 1982 PPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGA 2041 PP P R+E ++ +S+ S+H E TP +R R + S+ A Sbjct: 1737 PPAPCQCPRVESSMPEDRKSSTPGSLH-----EETPH------SRSTRENT----SRCSA 1781 Query: 2042 PGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSG 2101 P + + L++ L+ GLG A D FI T Q LADAC M EE+E A +L G Sbjct: 1782 P------ATALLIQKALVRGGLGTLAADANFIMATGQALADACQMEPEEVEIMATELLKG 1835 Query: 2102 GAPQSPNGALLPFVNCRDAGQDRAGGEEDAG 2132 ++P G + + C + G ++ G Sbjct: 1836 --REAPEG-MASSLGCLNLGSSLGSLDQHQG 1863 >gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F subunit [Homo sapiens] Length = 1977 Score = 2271 bits (5885), Expect = 0.0 Identities = 1261/2172 (58%), Positives = 1493/2172 (68%), Gaps = 266/2172 (12%) Query: 16 QGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATIST 75 +G +P P+ AN AG PE PG A + + G++G Sbjct: 5 EGGKDTTPEPSPAN-----GAGPGPEWGLCPGPP---------AVEGESSGASG------ 44 Query: 76 VSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIF 135 T ++R Q+ K K +A R PRAL CLTL NP+RR+CISIVEWKPF+I+ILLTIF Sbjct: 45 -LGTPKRRNQHSKHKTVAVASAQRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIF 103 Query: 136 ANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGW 195 ANCVAL +YIPFPEDDSN N NLE+VEY+FL+IFTVE LK++AYGL+ HP+AY+RNGW Sbjct: 104 ANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGW 163 Query: 196 NLLDFIIVVVGLFSAILEQATKADG-ANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSL 254 NLLDFIIVVVGLFS +LEQ G A GGK GFDVKALRAFRVLRPLRLVSGVPSL Sbjct: 164 NLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSL 223 Query: 255 QVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPS 314 +VLNSI+KA+VPLLHIALLVLFVIIIYAIIGLELF+G+MHKTCY +D+ AE+DPS Sbjct: 224 HIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLG--SDMEAEEDPS 281 Query: 315 PCALETGHGRQCQ-NGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 PCA +G GR C N T C+ W GP GITNFDNF FAMLTVFQC+TMEGWTDVLYW+ Sbjct: 282 PCA-SSGSGRACTLNQTECRGRWPGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQ 340 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA+G + PW+YFV+L+I GSFFVLNLVLGVLSGEFSKEREKAKARGDFQK REKQQ+EED Sbjct: 341 DAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKQREKQQMEED 400 Query: 434 LKGYLDWITQAEDIDPEN----------EDEGMDEEKPR--------------------- 462 L+GYLDWITQAE++D E+ +EG +P+ Sbjct: 401 LRGYLDWITQAEELDMEDPSADDNLGSMAEEGRAGHRPQLAELTNRRRGRLRWFSHSTRS 460 Query: 463 ------NMSMPTSETESVNTENVAGGDIEG--ENCGARLAHRISKSKFSRYWRRWNRFCR 514 + S+P S+T S+ + EG +C R ++I K++ R RR NR R Sbjct: 461 THSTSSHASLPASDTGSMTETQGDEDEEEGALASC-TRCLNKIMKTRVCRRLRRANRVLR 519 Query: 515 RKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLK 574 +CR AVKSN YW V+ LVFLNTLTIASEH+ QP WLT++Q+ ANK LL LFT EMLLK Sbjct: 520 ARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQIQEYANKVLLCLFTVEMLLK 579 Query: 575 MYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYW 634 +Y LG AY S FNRFDCFVVCGGILET LVE M PLGISVLRCVRLLRIFK+TR+W Sbjct: 580 LYGLGPSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHW 639 Query: 635 NSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQ 694 SLSNLVASLLNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFD+ T+RSTFD FPQ Sbjct: 640 ASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQ 699 Query: 695 SLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVD 754 +LLTVFQILTGEDWN VMYDGIMAYGGP FPGMLVCIYFIILFICGNYILLNVFLAIAVD Sbjct: 700 ALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVD 759 Query: 755 NLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGE 814 NLA ++ T+ K E+ E+ P++ + LV P V + +EE + Sbjct: 760 NLASGDAGTAKDKGGEKSNEKD------LPQENEGLV--PGVEKEEEEGARREGA----- 806 Query: 815 SPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPM 874 D++ E E+ EE+EEE E L E+ KEK VP+ Sbjct: 807 ----------DMEEEEEEE-----------EEEEEEEEEEGAGGVELLQEVVPKEKVVPI 845 Query: 875 PEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILG 934 PE SAFF S N R CH +++ +FTNLIL FI+LSS+SLAAEDP++ SFRNHILG Sbjct: 846 PEGSAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRNHILG 905 Query: 935 NADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVV 994 DY FTSIFT+EI+LKMT +GAFLH+GSFCR++FN+LDLLVVSVSLISFGI SSAI+VV Sbjct: 906 YFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHSSAISVV 965 Query: 995 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGK 1054 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Sbjct: 966 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGK 1025 Query: 1055 LYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTF 1114 YTC+D +K T ECKG+++ Y DG+V P+++ R W NS F+FDNVL+AMMALFTVSTF Sbjct: 1026 FYTCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTF 1085 Query: 1115 EGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE 1174 EGWP LLY++ID++ ED GPIYNYRVEIS+FFI+YIIIIAFFMMNIFVGFVI+TF+ QGE Sbjct: 1086 EGWPALLYKAIDAYAEDHGPIYNYRVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGE 1145 Query: 1175 QEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTI 1234 QEY+NCELDKNQRQCVEYALKA+PLRRYIPKN HQY+VW VNS FEYLMF+LILLNT+ Sbjct: 1146 QEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTV 1205 Query: 1235 CLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGS 1294 LAMQHY Q+ F AM+ILNM+FTGLFT+EM+LK+IAFKPK YF+D WN FD LIV+GS Sbjct: 1206 ALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFTDAWNTFDALIVVGS 1265 Query: 1295 IIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNN-------AEENSRISITFFRL 1347 I VDIA+TEVNN +E++SRISITFFRL Sbjct: 1266 I----------------------------VDIAVTEVNNGGHLGESSEDSSRISITFFRL 1297 Query: 1348 FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT 1407 FRVMRLVKLLS+GEGIRTLLWTFIKSFQALPYVALLI M+FFIYAVIGMQ+FGK+AL D Sbjct: 1298 FRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDG 1357 Query: 1408 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS 1467 T+INRNNNFQTFPQAVLLLFRCATGEAWQ+IMLA +PG +C PES+ E CGS+ Sbjct: 1358 TQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDPESDFGPGE--EFTCGSN 1415 Query: 1468 FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG 1527 FA+ YFISF+MLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDP AKG Sbjct: 1416 FAIAYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKG 1475 Query: 1528 RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL 1587 RIKHLDVV LLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTV FNATLFALVRT+L Sbjct: 1476 RIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVTFNATLFALVRTSL 1535 Query: 1588 RIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRK 1647 +IKTEGNLEQAN+ELR +IKKIWKR KLLD+V+PP ++EVTVGKFYATFLIQ+YFRK Sbjct: 1536 KIKTEGNLEQANQELRIVIKKIWKRMKQKLLDEVIPPPDEEEVTVGKFYATFLIQDYFRK 1595 Query: 1648 FKKRKEQGLVGKPSQRNALS-LQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSA 1706 F++RKE+GL+G + + S LQAGLR+L D+GPE+R+A++ D EEE +E V Sbjct: 1596 FRRRKEKGLLGNDAAPSTSSALQAGLRSLQDLGPEMRQALTCDTEEEEE---EGQEGVEE 1652 Query: 1707 ASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTES---PSHE 1763 E D+ T + +++ + +G S P + Sbjct: 1653 EDEKDL---------------------------ETNKATMVSQPSARRGSGISVSLPVGD 1685 Query: 1764 KLVDS-TFTPSS---YSSTGSNANINNANNTALGRLPRPAGYPSTVSTV--EGHGPPLSP 1817 +L DS +F PS + T S ++ A + R G + + T+ EG+ P Sbjct: 1686 RLPDSLSFGPSDDDRGTPTSSQPSVPQAGSNTHRR-----GSGALIFTIPEEGNSQP--- 1737 Query: 1818 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1877 GQ + +DE ++++ E P Sbjct: 1738 ----------------------KGTKGQNKQDEDEEVPDRLSYLDEQAGTPPC------- 1768 Query: 1878 YQDDENRQLTLPEEDKR--DIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKT 1935 L P +R D P+R L GR+ SF ++CL+RQ G Sbjct: 1769 ------SVLLPPHRAQRYMDGHLVPRRRLLPPTPAGRKPSFTIQCLQRQ----GSCED-- 1816 Query: 1936 VLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVE 1995 LP+ +H+ R+ P +ATPP RG L EG Sbjct: 1817 -LPIPGTYHRG-----------RNSGPNRAQGSWATPP----QRGRLLYAPLLLVEEGAA 1860 Query: 1996 SSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVE 2055 L G SS R L VP P GSA SLVE Sbjct: 1861 GEGYL-------------------GRSSGPLRTF-TCLHVPGTHSDPSHGKRGSADSLVE 1900 Query: 2056 AVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQ--SPNGALLP 2113 AVLISEGLG FA+DP+F+ + QE+ADAC +T++EM++AA ++L+ G S ++L Sbjct: 1901 AVLISEGLGLFARDPRFVALAKQEIADACRLTLDEMDNAASDLLAQGTSSLYSDEESILS 1960 Query: 2114 FVNCRDAGQDRA 2125 + D G + A Sbjct: 1961 RFDEEDLGDEMA 1972 >gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo sapiens] Length = 2261 Score = 764 bits (1974), Expect = 0.0 Identities = 409/886 (46%), Positives = 566/886 (63%), Gaps = 73/886 (8%) Query: 790 LVEKPAVGESKEEKIELKSITADGESPPATK--INMDDLQPNENEDKSPYPNPETTGEED 847 +V P+ ++ K K + PPA +N +Q N+N + P P E +E+ Sbjct: 1146 IVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKEEEKKEE 1205 Query: 848 EEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLIL 907 EE+ GP+P MP S+ FI S+ N R CH I+N F IL Sbjct: 1206 EEDDRGEDGPKP--------------MPPYSSMFILSTTNPLRRLCHYILNLRYFEMCIL 1251 Query: 908 FFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRN 967 I +SSI+LAAEDPVQ + RN++L DYVFT +FT E+++KM G LH+G++ R+ Sbjct: 1252 MVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRD 1311 Query: 968 YFNILDLLVVSVSLISFGIQSSA----INVVKILRVLRVLRPLRAINRAKGLKHVVQCVF 1023 +NILD +VVS +L++F ++ IN +K LRVLRVLRPL+ I R LK V CV Sbjct: 1312 LWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVV 1371 Query: 1024 VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH 1083 +++ + NI+IV L F+FA + VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV Sbjct: 1372 NSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVK- 1430 Query: 1084 PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS 1143 + R W+ +F +DNVL A++ LFTVST EGWP++L S+D+ E++GP YR+E+S Sbjct: 1431 --ARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMS 1488 Query: 1144 IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI 1203 IF+++Y ++ FF +NIFV +I+TFQEQG++ + L+KN+R C+++A+ A+PL R++ Sbjct: 1489 IFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHM 1548 Query: 1204 PKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGL 1261 P+N+ QY++W V S FEY + +I LNTI L M+ YG S ++ A+ + N++FT L Sbjct: 1549 PQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSL 1608 Query: 1262 FTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVG 1321 F++E +LK++AF IL+ YF DAWN FD + V+G Sbjct: 1609 FSLECVLKVMAFG------------------------ILN----YFRDAWNIFDFVTVLG 1640 Query: 1322 SIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVA 1381 SI DI +TE N + I+++F RLFR RL+KLL +G IR LLWTF++SF+ALPYV Sbjct: 1641 SITDILVTEFGN----NFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVC 1696 Query: 1382 LLIVMLFFIYAVIGMQVFGKIALN--------DTTEINRNNNFQTFPQAVLLLFRCATGE 1433 LLI MLFFIYA+IGMQVFG I ++ D +I +NNF+TF QA++LLFR ATGE Sbjct: 1697 LLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGE 1756 Query: 1434 AWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIM 1493 AW +IML+C+ GK C NS CG+ FA FYF+SF LC+FL++NLFVAVIM Sbjct: 1757 AWHNIMLSCLSGKPC-----DKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIM 1811 Query: 1494 DNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPH 1553 DNF+YLTRD SILGPHHLDE+ R+WAEYDP A GRI + D+ +LLR I PPLG GK CPH Sbjct: 1812 DNFEYLTRDSSILGPHHLDEYVRVWAEYDPAACGRIHYKDMYSLLRVISPPLGLGKKCPH 1871 Query: 1554 RVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE---GNLEQANEELRAIIKKIW 1610 RVACKRL+ M++P+ D TV FN+TL AL+RTAL IK + +Q + ELR + IW Sbjct: 1872 RVACKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKGGADKQQMDAELRKEMMAIW 1931 Query: 1611 KRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1656 S K LD +V P ++TVGK YA +I EY+R+ K +K Q + Sbjct: 1932 PNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKAKKLQAM 1977 Score = 671 bits (1730), Expect = 0.0 Identities = 383/827 (46%), Positives = 507/827 (61%), Gaps = 64/827 (7%) Query: 18 SNYGSPRPA-HANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTV 76 + +G PA + + AAAG+ GA S Q G G + Sbjct: 2 ARFGDEMPARYGGGGSGAAAGVVVGSGGGRGAGGSRQG-----------GQPGAQRMYKQ 50 Query: 77 SSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLT 133 S QR R Y P +Q T R +L + N +R+ I EW PFE +IL T Sbjct: 51 SMAQRARTMALYNPIPVRQNCLTVNR---SLFLFSEDNVVRKYAKKITEWPPFEYMILAT 107 Query: 134 IFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN 193 I ANC+ LA+ P+DD + L+ E F+ IF EA +K+IA G FH +YLRN Sbjct: 108 IIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRN 167 Query: 194 GWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPS 253 GWN++DF++V+ G+ + + G FD++ LRA RVLRPL+LVSG+PS Sbjct: 168 GWNVMDFVVVLTGILATV----------------GTEFDLRTLRAVRVLRPLKLVSGIPS 211 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 LQVVL SI+KAM+PLL I LL+ F I+I+AIIGLE +MGK H TC+ +EG D+ E P Sbjct: 212 LQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCF-EEGTDDIQGES-P 269 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 +PC E R C NGT C+P W+GP +GIT FDN FA+LTVFQCITMEGWTD+LY N Sbjct: 270 APCGTEEP-ARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSN 328 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA G W W+YF+ LIIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E + Sbjct: 329 DASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERE 388 Query: 434 LKGYLDWITQAEDIDPENEDEGMDEEKP-----RNMSMPTSETESVNTENVAGGDIEGEN 488 L GY++WI++AE++ ++ ++ P R ++ S+T+ +N E + + Sbjct: 389 LNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIKKSKTDLLNPEEAEDQLADIAS 448 Query: 489 CG---ARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEH 545 G AR + + +K + S ++ + R R R VK+ FYW V+ LV LNTL +A H Sbjct: 449 VGSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVH 508 Query: 546 YNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETIL 605 YNQP WL++ A L LF +EM +KMY LG + YF S FN FDC V+ G I E I Sbjct: 509 YNQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIW 568 Query: 606 VETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIF 665 K + GISVLR +RLLRIFK+T+YW SL NLV SLLNS++SI SLL LLFLFI++F Sbjct: 569 AVIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVF 628 Query: 666 SLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP 725 +LLGMQLFGG+FNFDE T + FD FP +++TVFQILTGEDWN VMYDGI + GG Sbjct: 629 ALLGMQLFGGQFNFDE-GTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQ-G 686 Query: 726 GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERK--------- 776 GM+ IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EEEE +K Sbjct: 687 GMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEV 746 Query: 777 ------KLARTASPEKKQELVEKPA--VGESKEEKIELKSITADGES 815 A + K+Q+ +KPA V E + ++ +++ A E+ Sbjct: 747 AEVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREA 793 Score = 202 bits (513), Expect = 4e-51 Identities = 176/705 (24%), Positives = 317/705 (44%), Gaps = 120/705 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 + K+++ + + P ++ L+ NP+RR C I+ + FE+ IL+ I + + Sbjct: 1200 EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI 1259 Query: 140 ALAIYIPFPEDDSNATNSNLERV-EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198 ALA P NA +N+ R +Y+F +FT E +K+I GL+ H AY R+ WN+L Sbjct: 1260 ALAAEDPV---QPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNIL 1316 Query: 199 DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258 DFI+V L + +K N +K+LR RVLRPL+ + +P L+ V Sbjct: 1317 DFIVVSGALVAFAFTGNSKGKDINT---------IKSLRVLRVLRPLKTIKRLPKLKAVF 1367 Query: 259 NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK-MHKTCYNQEGIADVPAEDDPSPCA 317 + ++ ++ + +I ++ + + I+A++ ++LF GK H T ++E D Sbjct: 1368 DCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDC---------- 1417 Query: 318 LETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV- 376 G + V + K+ ++DN +A+LT+F T EGW VL DA Sbjct: 1418 --RGKYLLYEKNEVKARDREWKKYEF-HYDNVLWALLTLFTVSTGEGWPQVLKHSVDATF 1474 Query: 377 --------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQ 428 R I++V ++ FF +N+ + ++ F ++ GD K+ E+ Sbjct: 1475 ENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KMMEEY 1525 Query: 429 QLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGEN 488 LE++ + +D+ A KP MP Sbjct: 1526 SLEKNERACIDFAISA---------------KPLTRHMP--------------------- 1549 Query: 489 CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ 548 ++K S +R W V S F + ++ ++ LNT+ + + Y Sbjct: 1550 ----------QNKQSFQYRMWQ---------FVVSPPFEYTIMAMIALNTIVLMMKFYGA 1590 Query: 549 PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVET 608 N +LF+ E +LK+ + G+ YF +N FD V G I + ILV Sbjct: 1591 SVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITD-ILVTE 1649 Query: 609 KIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLL 668 + + +S LR R R+ K+ R ++ L+ + + S +++ + LL+ + I++++ Sbjct: 1650 FGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1709 Query: 669 GMQLFGG--------KFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAY 719 GMQ+FG + DE Q T + F F Q+L+ +F+ TGE W+++M + Sbjct: 1710 GMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGK 1769 Query: 720 GGPSFPGML--------VCIYFI-ILFICGNYILLNVFLAIAVDN 755 G+L YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1770 PCDKNSGILTRECGNEFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1813 Score = 143 bits (360), Expect = 2e-33 Identities = 179/785 (22%), Positives = 325/785 (41%), Gaps = 161/785 (20%) Query: 480 AGGDIEGENCGARLAHRISKSKFSRYWRRWNRF-CRRKCRAAVKS-------NV------ 525 AGG +G GA+ ++ S ++ +R +N R+ C +S NV Sbjct: 33 AGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAK 92 Query: 526 -------FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKM 575 F ++++ + N + +A E + + ++E D + +F E +K+ Sbjct: 93 KITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKI 152 Query: 576 YSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT 631 +LG +Y + +N D VV GIL T+ E + LR VR+LR K+ Sbjct: 153 IALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTE------FDLRTLRAVRVLRPLKLV 206 Query: 632 RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF-------DEMQT 684 SL ++ S++ ++ + + LLLF I+IF+++G++ + GKF+ D++Q Sbjct: 207 SGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQG 266 Query: 685 RR------------------------------STFDNFPQSLLTVFQILTGEDWNSVMYD 714 + FDN ++LTVFQ +T E W ++Y+ Sbjct: 267 ESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYN 326 Query: 715 GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE 774 A G +YFI L I G++ +LN+ L + A +E+E Sbjct: 327 SNDASGNT-----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERE 368 Query: 775 RKKLARTASPEKKQELVEKPAVGE----SKEEKIELKSITADGES--PPATKINMDDLQP 828 R + R ++Q+ +E+ G SK E++ L DGE P + ++ Sbjct: 369 RVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIK- 427 Query: 829 NENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNR 888 + K+ NPE ED+ VG P + +K + E S FF R Sbjct: 428 ---KSKTDLLNPEEA--EDQLADIASVGS---PFARASIKSAKL---ENSTFF-HKKERR 475 Query: 889 FRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEI 948 R R+V F +L + L+++ +A Q + + L A+++F +F E+ Sbjct: 476 MRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQ-PEWLSDFLYYAEFIFLGLFMSEM 534 Query: 949 ILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRP 1005 +KM G + + FN D V+ S+ I+ + +LR LR+LR Sbjct: 535 FIKMYGLGT----RPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRI 590 Query: 1006 LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT 1065 + L+++V + ++++I +++ + L +FA +G+QLF G+ + + + T Sbjct: 591 FKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQ-FNFDEGTPPT 649 Query: 1066 EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI 1125 +FD AA+M +F + T E W E++Y I Sbjct: 650 -------------------------------NFDTFPAAIMTVFQILTGEDWNEVMYDGI 678 Query: 1126 DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEY 1177 S +G + SI+FI+ + + ++N+F+ + +T EQ E+E Sbjct: 679 KSQGGVQGGMV-----FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEA 733 Query: 1178 KNCEL 1182 N +L Sbjct: 734 ANQKL 738 Score = 116 bits (291), Expect = 2e-25 Identities = 96/331 (29%), Positives = 163/331 (49%), Gaps = 33/331 (9%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILGNA 936 + F+FS +N R +I F +IL I+ + I LA E P + + L + Sbjct: 77 SLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDT 136 Query: 937 DYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI-SFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV ++ + G + ++ Sbjct: 137 EPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFD----LR 192 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ +FA IG++ + GK Sbjct: 193 TLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252 Query: 1056 YT------CSDSSKQTEAEC--KGNYITYKDGEVDHPIIQPRSWE---NSKFDFDNVLAA 1104 +T D ++ A C + T +G P WE N FDN+L A Sbjct: 253 HTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPY-----WEGPNNGITQFDNILFA 307 Query: 1105 MMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 1164 ++ +F T EGW +LLY S D+ G +N+ ++FI III +FFM+N+ +G Sbjct: 308 VLTVFQCITMEGWTDLLYNSNDA----SGNTWNW-----LYFIPLIIIGSFFMLNLVLGV 358 Query: 1165 VIVTFQEQGEQ-EYKNCELDKNQRQCVEYAL 1194 + F ++ E+ E + L ++Q +E L Sbjct: 359 LSGEFAKERERVENRRAFLKLRRQQQIEREL 389 Score = 107 bits (267), Expect = 1e-22 Identities = 80/311 (25%), Positives = 142/311 (45%), Gaps = 59/311 (18%) Query: 1195 KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL 1254 K R +R YI + +V + F + + L+ LNT+C+A+ HY Q + Sbjct: 472 KERRMRFYIRR---------MVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYA 522 Query: 1255 NMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTF 1314 +F GLF EM +K+ + YF +N FD ++IGSI +VI W Sbjct: 523 EFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVI-----------W--- 568 Query: 1315 DALIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSF 1374 A+I G+ I++ R R++R+ K+ +R L+ + + S Sbjct: 569 -AVIKPGTSFGISV----------------LRALRLLRIFKVTKYWASLRNLVVSLLNSM 611 Query: 1375 QALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEA 1434 +++ + L+ + ++A++GMQ+FG + E NF TFP A++ +F+ TGE Sbjct: 612 KSIISLLFLLFLFIVVFALLGMQLFG--GQFNFDEGTPPTNFDTFPAAIMTVFQILTGED 669 Query: 1435 WQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMD 1494 W ++M ++G G F++ YFI + + ++N+F+A+ +D Sbjct: 670 WNEVMY-------------DGIKSQGGVQGGMVFSI-YFIVLTLFGNYTLLNVFLAIAVD 715 Query: 1495 NF---DYLTRD 1502 N LT+D Sbjct: 716 NLANAQELTKD 726 Score = 82.0 bits (201), Expect = 6e-15 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 62/297 (20%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N + L + S A + L +F +F++E LKV+A+G+L Sbjct: 1567 PFEYTIMAMIALNTIVLMMKF---YGASVAYENALRVFNIVFTSLFSLECVLKVMAFGIL 1623 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + G N + ++ LR FR R Sbjct: 1624 ----NYFRDAWNIFDFVTVLGSITDILVTEF----GNNFI-------NLSFLRLFRAARL 1668 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F GI Sbjct: 1669 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF---------GNIGI 1719 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 DV ED T H NF F A++ +F+ T E Sbjct: 1720 -DVEDEDSDEDEFQITEH---------------------NNFRTFFQALMLLFRSATGEA 1757 Query: 365 WTDVLY-------------WVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ + G ++ + YFV+ I + SF +LNL + V+ F Sbjct: 1758 WHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1814 Score = 61.6 bits (148), Expect = 8e-09 Identities = 73/319 (22%), Positives = 121/319 (37%), Gaps = 98/319 (30%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + ++ F G+F E +K+IA F Sbjct: 100 FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159 Query: 1274 KPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNN 1333 Y + WNV DF++V+ I L VG+ D+ Sbjct: 160 HKGSYLRNGWNVMDFVVVLTGI---------------------LATVGTEFDLRT----- 193 Query: 1334 AEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAV 1393 R RV+R +KL+S ++ +L + +K+ L + LL+ I+A+ Sbjct: 194 -----------LRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAI 242 Query: 1394 IGMQVF-GKI-----------------ALNDTTEINR---------------NNNFQTFP 1420 IG++ + GK A T E R NN F Sbjct: 243 IGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFD 302 Query: 1421 Q---AVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFY 1477 AVL +F+C T E W D++ NS + G+++ YFI Sbjct: 303 NILFAVLTVFQCITMEGWTDLLY---------------NSNDAS---GNTWNWLYFIPLI 344 Query: 1478 MLCAFLIINLFVAVIMDNF 1496 ++ +F ++NL + V+ F Sbjct: 345 IIGSFFMLNLVLGVLSGEF 363 >gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B subunit [Homo sapiens] Length = 2339 Score = 759 bits (1959), Expect = 0.0 Identities = 430/964 (44%), Positives = 589/964 (61%), Gaps = 91/964 (9%) Query: 764 SAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESP----PAT 819 + +KE E++ +K A +K++EL + +E +L++ P P+T Sbjct: 991 AVEKETTEKEATEKEAEIVEADKEKELRNH----QPREPHCDLETSGTVTVGPMHTLPST 1046 Query: 820 KINMDDLQPNENEDK-------SPYPNPETTGEEDEEEPEMPVGPRPR----PLSELHLK 868 + + QP + +++ S P+P T P M GP P + L+ Sbjct: 1047 CLQKVEEQPEDADNQRNVTRMGSQPPDPNTI----VHIPVMLTGPLGEATVVPSGNVDLE 1102 Query: 869 EKAV----------------PMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILL 912 +A P+ S+ F S N R CH IV F +IL I L Sbjct: 1103 SQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFCHYIVTMRYFEVVILVVIAL 1162 Query: 913 SSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNIL 972 SSI+LAAEDPV+ S RN+ L DY+FT +FT E+++KM G LH G++ R+ +NIL Sbjct: 1163 SSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNIL 1222 Query: 973 DLLVVSVSLISFGIQSSA---INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTI 1029 D +VVS +L++F S IN +K LRVLRVLRPL+ I R LK V CV +++ + Sbjct: 1223 DFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNV 1282 Query: 1030 GNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPR 1089 NI+IV L F+FA I VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV+ QPR Sbjct: 1283 LNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELERDCRGQYLDYEKEEVE---AQPR 1339 Query: 1090 SWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIY 1149 W+ F +DNVL A++ LFTVST EGWP +L S+D+ E++GP YR+E+SIF+++Y Sbjct: 1340 QWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVY 1399 Query: 1150 IIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH- 1208 ++ FF +NIFV +I+TFQEQG++ C L+KN+R C+++A+ A+PL RY+P+N+ Sbjct: 1400 FVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFAISAKPLTRYMPQNRQS 1459 Query: 1209 -QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMI 1267 QYK W V S FEY + +I LNT+ L M+ Y +++ + LN++FT +F++E + Sbjct: 1460 FQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECV 1519 Query: 1268 LKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIA 1327 LK+IAF YF D AWN FD + V+GSI DI Sbjct: 1520 LKIIAFGVLNYFRD----------------------------AWNVFDFVTVLGSITDIL 1551 Query: 1328 ITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML 1387 +TE+ AE N+ I+++F RLFR RL+KLL +G IR LLWTF++SF+ALPYV LLI ML Sbjct: 1552 VTEI--AETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAML 1609 Query: 1388 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK 1447 FFIYA+IGMQVFG IAL+D T INR+NNF+TF QA++LLFR ATGEAW +IML+C+ + Sbjct: 1610 FFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQA 1669 Query: 1448 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG 1507 C E +N+TE CGS FA FYF+SF LC+FL++NLFVAVIMDNF+YLTRD SILG Sbjct: 1670 C---DEQANATE----CGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILG 1722 Query: 1508 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL 1567 PHHLDEF R+WAEYDP A GRI + D+ +L+ + PPLG GK CP RVA KRLV MNMP+ Sbjct: 1723 PHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPI 1782 Query: 1568 -NSDGTVMFNATLFALVRTALRIK---TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVP 1623 N D TV F +TL AL+RTAL IK Q + ELR I +W K LD +VP Sbjct: 1783 SNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVP 1842 Query: 1624 PAGDDEVTVGKFYATFLIQEYFRKFKKRKE--QGLVGKPSQRNALSLQAGLR-TLHDIGP 1680 P DE+TVGK YA +I +++++ K ++ Q G SQ +SL L+ TL P Sbjct: 1843 PHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQP 1902 Query: 1681 EIRR 1684 + R Sbjct: 1903 AVLR 1906 Score = 648 bits (1671), Expect = 0.0 Identities = 371/803 (46%), Positives = 486/803 (60%), Gaps = 59/803 (7%) Query: 89 PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFP 148 P KQ T R +L + N +R+ I EW PFE +IL TI ANC+ LA+ P Sbjct: 63 PVKQNCFTVNR---SLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLP 119 Query: 149 EDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLF 208 + D + L+ E F+ IF EA +K+IA G +FH +YLRNGWN++DF++V+ G+ Sbjct: 120 DGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGI- 178 Query: 209 SAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPL 268 L G FD++ LRA RVLRPL+LVSG+PSLQVVL SI+KAMVPL Sbjct: 179 ---------------LATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPL 223 Query: 269 LHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQN 328 L I LL+ F I+++AIIGLE +MGK HK C+ A+ P D PC E R C+ Sbjct: 224 LQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAE-PVGD--FPCGKEAP-ARLCEG 279 Query: 329 GTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTL 388 T C+ W GP GITNFDN FA+LTVFQCITMEGWTD+LY NDA G W W+YF+ L Sbjct: 280 DTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPL 339 Query: 389 IIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDID 448 IIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E +L GYL+WI +AE++ Sbjct: 340 IIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVM 399 Query: 449 PENEDEGMDEEKP----RNMSMPTSETESVNTENVAGGDIEGENCG-----ARLAHRISK 499 ED +E+ P + + S + ++ E G D + C AR + + K Sbjct: 400 LAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAEE--GEDRFADLCAVGSPFARASLKSGK 457 Query: 500 SKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTA 559 ++ S Y+RR + R R VK+ FYW+V+ +V LNTL +A HYNQP LT A Sbjct: 458 TESSSYFRRKEKMFRFFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFA 517 Query: 560 NKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVL 619 L LF EM LKMY LG ++YF S FN FD V+ G + E + K S GISVL Sbjct: 518 EFVFLGLFLTEMSLKMYGLGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVL 577 Query: 620 RCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF 679 R +RLLRIFK+T+YW+SL NLV SLLNS++SI SLL LLFLFI++F+LLGMQLFGG+FNF Sbjct: 578 RALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNF 637 Query: 680 DEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFIC 739 + +T + FD FP ++LTVFQILTGEDWN+VMY GI + GG S GM YFI+L + Sbjct: 638 QD-ETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIESQGGVS-KGMFSSFYFIVLTLF 695 Query: 740 GNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE-------------- 785 GNY LLNVFLAIAVDNLA+A+ LT +EE EE +KLA + E Sbjct: 696 GNYTLLNVFLAIAVDNLANAQELTK-DEEEMEEAANQKLALQKAKEVAEVSPMSAANISI 754 Query: 786 --KKQELVEKPAVGESKEEKIELKSITAD-----GESPPATKINMDDLQPNENEDKSPYP 838 ++Q + +V E + ++ L+++ A E P ++ + + K+ Sbjct: 755 AARQQNSAKARSVWEQRASQLRLQNLRASCEALYSEMDPEERLRFATTRHLRPDMKTHLD 814 Query: 839 NPETTGEEDEEEPEMPVGPRPRP 861 P E + PVG + RP Sbjct: 815 RPLVV-ELGRDGARGPVGGKARP 836 Score = 216 bits (550), Expect = 2e-55 Identities = 179/716 (25%), Positives = 322/716 (44%), Gaps = 113/716 (15%) Query: 64 LMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPR------ALLCLTLKNPIRRAC 117 L G G AT+ + + Q GK + + PR ++ CL+ N +RR C Sbjct: 1084 LTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFC 1143 Query: 118 ISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK 177 IV + FE++IL+ I + +ALA P D N+ L+ ++Y+F +FT E +K Sbjct: 1144 HYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPR--NNALKYLDYIFTGVFTFEMVIK 1201 Query: 178 VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR 237 +I GLL HP AY R+ WN+LDF IVV G A +K N +K+LR Sbjct: 1202 MIDLGLLLHPGAYFRDLWNILDF-IVVSGALVAFAFSGSKGKDINT---------IKSLR 1251 Query: 238 AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT 297 RVLRPL+ + +P L+ V + ++ ++ +L+I ++ + + I+A+I ++LF GK Sbjct: 1252 VLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFF-Y 1310 Query: 298 CYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVF 357 C ++ + E + Q W K ++DN +A+LT+F Sbjct: 1311 CTDESKELERDCRGQYLDYEKEEVEAQPRQ--------W---KKYDFHYDNVLWALLTLF 1359 Query: 358 QCITMEGWTDVLYWVNDAVGRDWP---------WIYFVTLIIIGSFFVLNLVLGVLSGEF 408 T EGW VL DA + I++V ++ FF +N+ + ++ F Sbjct: 1360 TVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITF 1419 Query: 409 SKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPT 468 ++ GD K+ + LE++ + +D+ A KP MP Sbjct: 1420 QEQ-------GD--KVMSECSLEKNERACIDFAISA---------------KPLTRYMP- 1454 Query: 469 SETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYW 528 +++ S ++ W V S F + Sbjct: 1455 ------------------------------QNRQSFQYKTW---------TFVVSPPFEY 1475 Query: 529 LVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLF 588 ++ ++ LNT+ + + Y+ P + N ++F+ E +LK+ + G+ YF + Sbjct: 1476 FIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAW 1535 Query: 589 NRFDCFVVCGGILETILVE-TKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNS 647 N FD V G I + ++ E + + + +S LR R R+ K+ R ++ L+ + + S Sbjct: 1536 NVFDFVTVLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQS 1595 Query: 648 VRSIASLLLLLFLFIIIFSLLGMQLFGG-KFNFDEMQTRRSTFDNFPQSLLTVFQILTGE 706 +++ + LL+ + I++++GMQ+FG + D R + F F Q+L+ +F+ TGE Sbjct: 1596 FKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGE 1655 Query: 707 DWNSVMYDGIMAYGGPSFPGMLVC------IYFI-ILFICGNYILLNVFLAIAVDN 755 W+ +M + C YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1656 AWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1710 Score = 125 bits (315), Expect = 3e-28 Identities = 161/728 (22%), Positives = 302/728 (41%), Gaps = 146/728 (20%) Query: 526 FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQ- 581 F ++++ + N + +A E + ++E D + +F E +K+ +LG Sbjct: 97 FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156 Query: 582 ---AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLS 638 +Y + +N D VV GIL T + + LR VR+LR K+ SL Sbjct: 157 HKGSYLRNGWNVMDFVVVLTGILATAGTD------FDLRTLRAVRVLRPLKLVSGIPSLQ 210 Query: 639 NLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF------------------- 679 ++ S++ ++ + + LLLF I++F+++G++ + GKF+ Sbjct: 211 VVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAEPVGDFPCGK 270 Query: 680 --------DEMQTRR---------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGP 722 + + R + FDN ++LTVFQ +T E W ++Y+ A G Sbjct: 271 EAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNT 330 Query: 723 SFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTA 782 +YFI L I G++ +LN+ L + A +E+ER + R Sbjct: 331 -----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERERVENRRAF 372 Query: 783 SPEKKQELVEKPAVG------ESKEEKIELKSITADGESP------PATKINMDDLQPNE 830 ++Q+ +E+ G +++E + + A+ +SP ATK + +DL E Sbjct: 373 LKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAE 432 Query: 831 NEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFR 890 ED VG P + LK E+S++F FR Sbjct: 433 EG-------------EDRFADLCAVGS---PFARASLKSGKT---ESSSYFR-RKEKMFR 472 Query: 891 LQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIIL 950 R+V F ++L + L+++ +A Q L A++VF +F E+ L Sbjct: 473 FFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTT-TLYFAEFVFLGLFLTEMSL 531 Query: 951 KMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRPLR 1007 KM YG L S+ R+ FN D V+ S+ I+ + + +LR LR+LR + Sbjct: 532 KM--YG--LGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFK 587 Query: 1008 AINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEA 1067 L+++V + ++++I +++ + L +FA +G+QLF G+ Sbjct: 588 VTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQF------------ 635 Query: 1068 ECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDS 1127 ++D E +FD AA++ +F + T E W ++Y I+S Sbjct: 636 -------NFQD-------------ETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIES 675 Query: 1128 HTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE--QEYKNCELDKN 1185 +++ S +FI+ + + ++N+F+ + E ++ + E N Sbjct: 676 QGGVSKGMFS-----SFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEMEEAAN 730 Query: 1186 QRQCVEYA 1193 Q+ ++ A Sbjct: 731 QKLALQKA 738 Score = 119 bits (298), Expect = 3e-26 Identities = 80/292 (27%), Positives = 138/292 (47%), Gaps = 52/292 (17%) Query: 1215 VVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFK 1274 +V + F +++ ++ LNT+C+AM HY Q + +F GLF EM LK+ Sbjct: 478 MVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLG 537 Query: 1275 PKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNNA 1334 P+ YF +N FDF +++GS+ +V+ W A I GS I++ Sbjct: 538 PRSYFRSSFNCFDFGVIVGSVFEVV-----------W----AAIKPGSSFGISV------ 576 Query: 1335 EENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVI 1394 R R++R+ K+ +R L+ + + S +++ + L+ + ++A++ Sbjct: 577 ----------LRALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALL 626 Query: 1395 GMQVF-GKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESE 1453 GMQ+F G+ D T NF TFP A+L +F+ TGE W +M + ES+ Sbjct: 627 GMQLFGGQFNFQDETP---TTNFDTFPAAILTVFQILTGEDWNAVMYHGI-------ESQ 676 Query: 1454 PSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1502 S F+ FYFI + + ++N+F+A+ +DN LT+D Sbjct: 677 GGVSK-------GMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 721 Score = 118 bits (296), Expect = 5e-26 Identities = 94/326 (28%), Positives = 164/326 (50%), Gaps = 24/326 (7%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILGNA 936 + F+FS +N R RI F +IL I+ + I LA E P + + L + Sbjct: 74 SLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDT 133 Query: 937 DYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKI 996 + F IF E +K+ A G HKGS+ RN +N++D +VV +++ + ++ Sbjct: 134 EPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA---TAGTDFDLRT 190 Query: 997 LRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLY 1056 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ MFA IG++ + GK + Sbjct: 191 LRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFH 250 Query: 1057 -TCSDSSKQTEAECKGNYITYKDGEV---DHPIIQPRSWENSKF---DFDNVLAAMMALF 1109 C +S T+AE G++ K+ + W F +FDN+L A++ +F Sbjct: 251 KACFPNS--TDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVF 308 Query: 1110 TVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTF 1169 T EGW ++LY + D+ G +N+ ++FI III +FFM+N+ +G + F Sbjct: 309 QCITMEGWTDILYNTNDA----AGNTWNW-----LYFIPLIIIGSFFMLNLVLGVLSGEF 359 Query: 1170 QEQGEQ-EYKNCELDKNQRQCVEYAL 1194 ++ E+ E + L ++Q +E L Sbjct: 360 AKERERVENRRAFLKLRRQQQIEREL 385 Score = 83.2 bits (204), Expect = 3e-15 Identities = 70/295 (23%), Positives = 130/295 (44%), Gaps = 66/295 (22%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N V L + D L+ + +F +F++E LK+IA+G+L Sbjct: 1472 PFEYFIMAMIALNTVVLMMKF---YDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVL 1528 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + + + ++ LR FR R Sbjct: 1529 ----NYFRDAWNVFDFVTVLGSITDILVTEIAETNNF---------INLSFLRLFRAARL 1575 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F Sbjct: 1576 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-------------- 1621 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 ++ +DD S +H NF F A++ +F+ T E Sbjct: 1622 GNIALDDDTSI-----------------------NRHN--NFRTFLQALMLLFRSATGEA 1656 Query: 365 WTDVLYWV--NDAV---------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ N A G D+ + YFV+ I + SF +LNL + V+ F Sbjct: 1657 WHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1711 Score = 62.8 bits (151), Expect = 4e-09 Identities = 65/318 (20%), Positives = 118/318 (37%), Gaps = 97/318 (30%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + G ++ F G+F E +K+IA F Sbjct: 97 FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156 Query: 1274 KPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNN 1333 Y + WNV DF++V+ I+ Sbjct: 157 HKGSYLRNGWNVMDFVVVLTGIL------------------------------------- 179 Query: 1334 AEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAV 1393 A + + R RV+R +KL+S ++ +L + +K+ L + LL+ ++A+ Sbjct: 180 ATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAI 239 Query: 1394 IGMQV----FGKIALNDTTEIN-------------------------------RNNNFQT 1418 IG++ F K ++T+ NF Sbjct: 240 IGLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDN 299 Query: 1419 FPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYM 1478 A+L +F+C T E W DI+ N+ + G+++ YFI + Sbjct: 300 ILFAILTVFQCITMEGWTDILY---------------NTNDA---AGNTWNWLYFIPLII 341 Query: 1479 LCAFLIINLFVAVIMDNF 1496 + +F ++NL + V+ F Sbjct: 342 IGSFFMLNLVLGVLSGEF 359 >gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo sapiens] Length = 2506 Score = 756 bits (1952), Expect = 0.0 Identities = 405/886 (45%), Positives = 564/886 (63%), Gaps = 73/886 (8%) Query: 790 LVEKPAVGESKEEKIELKSITADGESPPATK--INMDDLQPNENEDKSPYPNPETTGEED 847 +V P+ ++ K K + PPA +N +Q N+N + P P E +E+ Sbjct: 1145 IVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKEEEKKEE 1204 Query: 848 EEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLIL 907 EE+ GP+P MP S+ FI S+ N R CH I+N F IL Sbjct: 1205 EEDDRGEDGPKP--------------MPPYSSMFILSTTNPLRRLCHYILNLRYFEMCIL 1250 Query: 908 FFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRN 967 I +SSI+LAAEDPVQ + RN++L DYVFT +FT E+++KM G LH+G++ R+ Sbjct: 1251 MVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRD 1310 Query: 968 YFNILDLLVVSVSLISFGIQSSA----INVVKILRVLRVLRPLRAINRAKGLKHVVQCVF 1023 +NILD +VVS +L++F ++ IN +K LRVLRVLRPL+ I R LK V CV Sbjct: 1311 LWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVV 1370 Query: 1024 VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH 1083 +++ + NI+IV L F+FA + VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV Sbjct: 1371 NSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVK- 1429 Query: 1084 PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS 1143 + R W+ +F +DNVL A++ LFTVST EGWP++L S+D+ E++GP YR+E+S Sbjct: 1430 --ARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMS 1487 Query: 1144 IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI 1203 IF+++Y ++ FF +NIFV +I+TFQEQG++ + L+KN+R C+++A+ A+PL R++ Sbjct: 1488 IFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHM 1547 Query: 1204 PKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGL 1261 P+N+ QY++W V S FEY + +I LNTI L M+ YG S ++ A+ + N++FT L Sbjct: 1548 PQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSL 1607 Query: 1262 FTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVG 1321 F++E +LK++AF IL+ YF DAWN FD + V+G Sbjct: 1608 FSLECVLKVMAFG------------------------ILN----YFRDAWNIFDFVTVLG 1639 Query: 1322 SIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVA 1381 SI DI +TE N + I+++F RLFR RL+KLL +G IR LLWTF++SF+ALPYV Sbjct: 1640 SITDILVTEFGN----NFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVC 1695 Query: 1382 LLIVMLFFIYAVIGMQVFGKIALN--------DTTEINRNNNFQTFPQAVLLLFRCATGE 1433 LLI MLFFIYA+IGMQVFG I ++ D +I +NNF+TF QA++LLFR ATGE Sbjct: 1696 LLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGE 1755 Query: 1434 AWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIM 1493 AW +IML+C+ GK C NS CG+ FA FYF+SF LC+FL++NLFVAVIM Sbjct: 1756 AWHNIMLSCLSGKPC-----DKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIM 1810 Query: 1494 DNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPH 1553 DNF+YLTRD SILGPHHLDE+ R+WAEYDP A GR+ +LD+ +LR + PPLG GK CP Sbjct: 1811 DNFEYLTRDSSILGPHHLDEYVRVWAEYDPAAWGRMPYLDMYQMLRHMSPPLGLGKKCPA 1870 Query: 1554 RVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE---GNLEQANEELRAIIKKIW 1610 RVA KRL+ M++P+ D TV FN+TL AL+RTAL IK + +Q + ELR + IW Sbjct: 1871 RVAYKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKGGADKQQMDAELRKEMMAIW 1930 Query: 1611 KRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1656 S K LD +V P ++TVGK YA +I EY+R+ K +K Q + Sbjct: 1931 PNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKAKKLQAM 1976 Score = 671 bits (1731), Expect = 0.0 Identities = 383/826 (46%), Positives = 507/826 (61%), Gaps = 63/826 (7%) Query: 18 SNYGSPRPA-HANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTV 76 + +G PA + + AAAG+ GA S Q G G + Sbjct: 2 ARFGDEMPARYGGGGSGAAAGVVVGSGGGRGAGGSRQG-----------GQPGAQRMYKQ 50 Query: 77 SSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLT 133 S QR R Y P +Q T R +L + N +R+ I EW PFE +IL T Sbjct: 51 SMAQRARTMALYNPIPVRQNCLTVNR---SLFLFSEDNVVRKYAKKITEWPPFEYMILAT 107 Query: 134 IFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN 193 I ANC+ LA+ P+DD + L+ E F+ IF EA +K+IA G FH +YLRN Sbjct: 108 IIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRN 167 Query: 194 GWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPS 253 GWN++DF++V+ G+ + + G FD++ LRA RVLRPL+LVSG+PS Sbjct: 168 GWNVMDFVVVLTGILATV----------------GTEFDLRTLRAVRVLRPLKLVSGIPS 211 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 LQVVL SI+KAM+PLL I LL+ F I+I+AIIGLE +MGK H TC+ +EG D+ E P Sbjct: 212 LQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCF-EEGTDDIQGES-P 269 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 +PC E R C NGT C+P W+GP +GIT FDN FA+LTVFQCITMEGWTD+LY N Sbjct: 270 APCGTEEP-ARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSN 328 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA G W W+YF+ LIIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E + Sbjct: 329 DASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERE 388 Query: 434 LKGYLDWITQAEDIDPENEDEGMDEEKP----RNMSMPTSETESVNTENVAGGDIEGENC 489 L GY++WI++AE++ ++ ++ P R ++ S+T+ +N E + + Sbjct: 389 LNGYMEWISKAEEVILAEDETDGEQRHPFDALRRTTIKKSKTDLLNPEEAEDQLADIASV 448 Query: 490 G---ARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHY 546 G AR + + +K + S ++ + R R R VK+ FYW V+ LV LNTL +A HY Sbjct: 449 GSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHY 508 Query: 547 NQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILV 606 NQP WL++ A L LF +EM +KMY LG + YF S FN FDC V+ G I E I Sbjct: 509 NQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWA 568 Query: 607 ETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFS 666 K + GISVLR +RLLRIFK+T+YW SL NLV SLLNS++SI SLL LLFLFI++F+ Sbjct: 569 VIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFA 628 Query: 667 LLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPG 726 LLGMQLFGG+FNFDE T + FD FP +++TVFQILTGEDWN VMYDGI + GG G Sbjct: 629 LLGMQLFGGQFNFDE-GTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQ-GG 686 Query: 727 MLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERK---------- 776 M+ IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EEEE +K Sbjct: 687 MVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEVA 746 Query: 777 -----KLARTASPEKKQELVEKPA--VGESKEEKIELKSITADGES 815 A + K+Q+ +KPA V E + ++ +++ A E+ Sbjct: 747 EVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREA 792 Score = 202 bits (513), Expect = 4e-51 Identities = 176/705 (24%), Positives = 317/705 (44%), Gaps = 120/705 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 + K+++ + + P ++ L+ NP+RR C I+ + FE+ IL+ I + + Sbjct: 1199 EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI 1258 Query: 140 ALAIYIPFPEDDSNATNSNLERV-EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198 ALA P NA +N+ R +Y+F +FT E +K+I GL+ H AY R+ WN+L Sbjct: 1259 ALAAEDPV---QPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNIL 1315 Query: 199 DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258 DFI+V L + +K N +K+LR RVLRPL+ + +P L+ V Sbjct: 1316 DFIVVSGALVAFAFTGNSKGKDINT---------IKSLRVLRVLRPLKTIKRLPKLKAVF 1366 Query: 259 NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK-MHKTCYNQEGIADVPAEDDPSPCA 317 + ++ ++ + +I ++ + + I+A++ ++LF GK H T ++E D Sbjct: 1367 DCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDC---------- 1416 Query: 318 LETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV- 376 G + V + K+ ++DN +A+LT+F T EGW VL DA Sbjct: 1417 --RGKYLLYEKNEVKARDREWKKYEF-HYDNVLWALLTLFTVSTGEGWPQVLKHSVDATF 1473 Query: 377 --------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQ 428 R I++V ++ FF +N+ + ++ F ++ GD K+ E+ Sbjct: 1474 ENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KMMEEY 1524 Query: 429 QLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGEN 488 LE++ + +D+ A KP MP Sbjct: 1525 SLEKNERACIDFAISA---------------KPLTRHMP--------------------- 1548 Query: 489 CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ 548 ++K S +R W V S F + ++ ++ LNT+ + + Y Sbjct: 1549 ----------QNKQSFQYRMWQ---------FVVSPPFEYTIMAMIALNTIVLMMKFYGA 1589 Query: 549 PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVET 608 N +LF+ E +LK+ + G+ YF +N FD V G I + ILV Sbjct: 1590 SVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITD-ILVTE 1648 Query: 609 KIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLL 668 + + +S LR R R+ K+ R ++ L+ + + S +++ + LL+ + I++++ Sbjct: 1649 FGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1708 Query: 669 GMQLFGG--------KFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAY 719 GMQ+FG + DE Q T + F F Q+L+ +F+ TGE W+++M + Sbjct: 1709 GMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGK 1768 Query: 720 GGPSFPGML--------VCIYFI-ILFICGNYILLNVFLAIAVDN 755 G+L YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1769 PCDKNSGILTRECGNEFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1812 Score = 144 bits (364), Expect = 7e-34 Identities = 179/784 (22%), Positives = 325/784 (41%), Gaps = 160/784 (20%) Query: 480 AGGDIEGENCGARLAHRISKSKFSRYWRRWNRF-CRRKCRAAVKS-------NV------ 525 AGG +G GA+ ++ S ++ +R +N R+ C +S NV Sbjct: 33 AGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAK 92 Query: 526 -------FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKM 575 F ++++ + N + +A E + + ++E D + +F E +K+ Sbjct: 93 KITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKI 152 Query: 576 YSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT 631 +LG +Y + +N D VV GIL T+ E + LR VR+LR K+ Sbjct: 153 IALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTE------FDLRTLRAVRVLRPLKLV 206 Query: 632 RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF-------DEMQT 684 SL ++ S++ ++ + + LLLF I+IF+++G++ + GKF+ D++Q Sbjct: 207 SGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQG 266 Query: 685 RR------------------------------STFDNFPQSLLTVFQILTGEDWNSVMYD 714 + FDN ++LTVFQ +T E W ++Y+ Sbjct: 267 ESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYN 326 Query: 715 GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE 774 A G +YFI L I G++ +LN+ L + A +E+E Sbjct: 327 SNDASGNT-----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERE 368 Query: 775 RKKLARTASPEKKQELVEKPAVGE----SKEEKIELKSITADGESP-PATKINMDDLQPN 829 R + R ++Q+ +E+ G SK E++ L DGE P + ++ Sbjct: 369 RVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDALRRTTIK-- 426 Query: 830 ENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRF 889 + K+ NPE ED+ VG P + +K + E S FF R Sbjct: 427 --KSKTDLLNPEEA--EDQLADIASVGS---PFARASIKSAKL---ENSTFF-HKKERRM 475 Query: 890 RLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEII 949 R R+V F +L + L+++ +A Q + + L A+++F +F E+ Sbjct: 476 RFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQ-PEWLSDFLYYAEFIFLGLFMSEMF 534 Query: 950 LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRPL 1006 +KM G + + FN D V+ S+ I+ + +LR LR+LR Sbjct: 535 IKMYGLGT----RPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIF 590 Query: 1007 RAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTE 1066 + L+++V + ++++I +++ + L +FA +G+QLF G+ + + + T Sbjct: 591 KVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQ-FNFDEGTPPT- 648 Query: 1067 AECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSID 1126 +FD AA+M +F + T E W E++Y I Sbjct: 649 ------------------------------NFDTFPAAIMTVFQILTGEDWNEVMYDGIK 678 Query: 1127 SHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEYK 1178 S +G + SI+FI+ + + ++N+F+ + +T EQ E+E Sbjct: 679 SQGGVQGGMV-----FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAA 733 Query: 1179 NCEL 1182 N +L Sbjct: 734 NQKL 737 Score = 116 bits (291), Expect = 2e-25 Identities = 96/331 (29%), Positives = 163/331 (49%), Gaps = 33/331 (9%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILGNA 936 + F+FS +N R +I F +IL I+ + I LA E P + + L + Sbjct: 77 SLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDT 136 Query: 937 DYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI-SFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV ++ + G + ++ Sbjct: 137 EPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFD----LR 192 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ +FA IG++ + GK Sbjct: 193 TLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252 Query: 1056 YT------CSDSSKQTEAEC--KGNYITYKDGEVDHPIIQPRSWE---NSKFDFDNVLAA 1104 +T D ++ A C + T +G P WE N FDN+L A Sbjct: 253 HTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPY-----WEGPNNGITQFDNILFA 307 Query: 1105 MMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 1164 ++ +F T EGW +LLY S D+ G +N+ ++FI III +FFM+N+ +G Sbjct: 308 VLTVFQCITMEGWTDLLYNSNDA----SGNTWNW-----LYFIPLIIIGSFFMLNLVLGV 358 Query: 1165 VIVTFQEQGEQ-EYKNCELDKNQRQCVEYAL 1194 + F ++ E+ E + L ++Q +E L Sbjct: 359 LSGEFAKERERVENRRAFLKLRRQQQIEREL 389 Score = 107 bits (267), Expect = 1e-22 Identities = 80/311 (25%), Positives = 142/311 (45%), Gaps = 59/311 (18%) Query: 1195 KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL 1254 K R +R YI + +V + F + + L+ LNT+C+A+ HY Q + Sbjct: 471 KERRMRFYIRR---------MVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYA 521 Query: 1255 NMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTF 1314 +F GLF EM +K+ + YF +N FD ++IGSI +VI W Sbjct: 522 EFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVI-----------W--- 567 Query: 1315 DALIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSF 1374 A+I G+ I++ R R++R+ K+ +R L+ + + S Sbjct: 568 -AVIKPGTSFGISV----------------LRALRLLRIFKVTKYWASLRNLVVSLLNSM 610 Query: 1375 QALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEA 1434 +++ + L+ + ++A++GMQ+FG + E NF TFP A++ +F+ TGE Sbjct: 611 KSIISLLFLLFLFIVVFALLGMQLFG--GQFNFDEGTPPTNFDTFPAAIMTVFQILTGED 668 Query: 1435 WQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMD 1494 W ++M ++G G F++ YFI + + ++N+F+A+ +D Sbjct: 669 WNEVMY-------------DGIKSQGGVQGGMVFSI-YFIVLTLFGNYTLLNVFLAIAVD 714 Query: 1495 NF---DYLTRD 1502 N LT+D Sbjct: 715 NLANAQELTKD 725 Score = 82.0 bits (201), Expect = 6e-15 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 62/297 (20%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N + L + S A + L +F +F++E LKV+A+G+L Sbjct: 1566 PFEYTIMAMIALNTIVLMMKF---YGASVAYENALRVFNIVFTSLFSLECVLKVMAFGIL 1622 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + G N + ++ LR FR R Sbjct: 1623 ----NYFRDAWNIFDFVTVLGSITDILVTEF----GNNFI-------NLSFLRLFRAARL 1667 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F GI Sbjct: 1668 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF---------GNIGI 1718 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 DV ED T H NF F A++ +F+ T E Sbjct: 1719 -DVEDEDSDEDEFQITEH---------------------NNFRTFFQALMLLFRSATGEA 1756 Query: 365 WTDVLY-------------WVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ + G ++ + YFV+ I + SF +LNL + V+ F Sbjct: 1757 WHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1813 Score = 61.6 bits (148), Expect = 8e-09 Identities = 73/319 (22%), Positives = 121/319 (37%), Gaps = 98/319 (30%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + ++ F G+F E +K+IA F Sbjct: 100 FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159 Query: 1274 KPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNN 1333 Y + WNV DF++V+ I L VG+ D+ Sbjct: 160 HKGSYLRNGWNVMDFVVVLTGI---------------------LATVGTEFDLRT----- 193 Query: 1334 AEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAV 1393 R RV+R +KL+S ++ +L + +K+ L + LL+ I+A+ Sbjct: 194 -----------LRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAI 242 Query: 1394 IGMQVF-GKI-----------------ALNDTTEINR---------------NNNFQTFP 1420 IG++ + GK A T E R NN F Sbjct: 243 IGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFD 302 Query: 1421 Q---AVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFY 1477 AVL +F+C T E W D++ NS + G+++ YFI Sbjct: 303 NILFAVLTVFQCITMEGWTDLLY---------------NSNDAS---GNTWNWLYFIPLI 344 Query: 1478 MLCAFLIINLFVAVIMDNF 1496 ++ +F ++NL + V+ F Sbjct: 345 IIGSFFMLNLVLGVLSGEF 363 >gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E subunit [Homo sapiens] Length = 2270 Score = 736 bits (1899), Expect = 0.0 Identities = 390/850 (45%), Positives = 546/850 (64%), Gaps = 55/850 (6%) Query: 833 DKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQ 892 D P E EDEEE E + + +E M S+ FIFS+ N R Sbjct: 1093 DGEASPLKEAEIREDEEEVEKKKQKKEK-------RETGKAMVPHSSMFIFSTTNPIRRA 1145 Query: 893 CHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKM 952 CH IVN F IL I SSI+LAAEDPV S RN +L DYVFT +FT E+++KM Sbjct: 1146 CHYIVNLRYFEMCILLVIAASSIALAAEDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKM 1205 Query: 953 TAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA-------INVVKILRVLRVLRP 1005 G L GS+ R+ +NILD +VV +L++F + ++ I +K LRVLRVLRP Sbjct: 1206 IDQGLILQDGSYFRDLWNILDFVVVVGALVAFALANALGTNKGRDIKTIKSLRVLRVLRP 1265 Query: 1006 LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT 1065 L+ I R LK V CV +++ + NI+IV L F+FA I VQLFKGK + C+DSSK T Sbjct: 1266 LKTIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKDT 1325 Query: 1066 EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI 1125 E EC GNY+ ++ +++ ++ R W+ +F +DN++ A++ LFTVST EGWP++L S+ Sbjct: 1326 EKECIGNYVDHEKNKME---VKGREWKRHEFHYDNIIWALLTLFTVSTGEGWPQVLQHSV 1382 Query: 1126 DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKN 1185 D ED+GP + R+E+SIF+++Y ++ FF +NIFV +I+TFQEQG++ + C L+KN Sbjct: 1383 DVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLEKN 1442 Query: 1186 QRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQ 1243 +R C+++A+ A+PL RY+P+N+H QY+VW+ V S FEY + +I LNT+ L M++Y Sbjct: 1443 ERACIDFAISAKPLTRYMPQNRHTFQYRVWHFVVSPSFEYTIMAMIALNTVVLMMKYYSA 1502 Query: 1244 SCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSET 1303 C +++A+ LN+ FT +F++E +LK+IAF FL Sbjct: 1503 PCTYELALKYLNIAFTMVFSLECVLKVIAF-------------GFL-------------- 1535 Query: 1304 NHYFCDAWNTFDALIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGI 1363 +YF D WN FD + V+GSI +I +T+ + S +++F +LFR RL+KLL +G I Sbjct: 1536 -NYFRDTWNIFDFITVIGSITEIILTD-SKLVNTSGFNMSFLKLFRAARLIKLLRQGYTI 1593 Query: 1364 RTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAV 1423 R LLWTF++SF+ALPYV LLI MLFFIYA+IGMQVFG I L++ + INR+NNF++F ++ Sbjct: 1594 RILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLDEESHINRHNNFRSFFGSL 1653 Query: 1424 LLLFRCATGEAWQDIMLACMPGKKCAPESE-PSNSTEGETPCGSSFAVFYFISFYMLCAF 1482 +LLFR ATGEAWQ+IML+C+ K C P++ PS E E CG+ A YF+SF C+F Sbjct: 1654 MLLFRSATGEAWQEIMLSCLGEKGCEPDTTAPSGQNENER-CGTDLAYVYFVSFIFFCSF 1712 Query: 1483 LIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQ 1542 L++NLFVAVIMDNF+YLTRD SILGPHHLDEF R+WAEYD A GRI + ++ +L + Sbjct: 1713 LMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFVRVWAEYDRAACGRIHYTEMYEMLTLMS 1772 Query: 1543 PPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE---GNLEQAN 1599 PPLG GK CP +VA KRLV MNMP+ D TV F +TL AL+RTAL IK + +Q + Sbjct: 1773 PPLGLGKRCPSKVAYKRLVLMNMPVAEDMTVHFTSTLMALIRTALDIKIAKGGADRQQLD 1832 Query: 1600 EELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGK 1659 EL+ IW S K+LD +VP ++TVGK YA +I +Y+++ K +K++ + Sbjct: 1833 SELQKETLAIWPHLSQKMLDLLVPMPKASDLTVGKIYAAMMIMDYYKQSKVKKQRQQL-- 1890 Query: 1660 PSQRNALSLQ 1669 Q+NA Q Sbjct: 1891 EEQKNAPMFQ 1900 Score = 630 bits (1626), Expect = e-180 Identities = 359/754 (47%), Positives = 468/754 (62%), Gaps = 35/754 (4%) Query: 60 RQAKLMGSAGNATISTVSSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRA 116 RQ + ++G A + QR R Y P +Q T R +L N +R+ Sbjct: 25 RQGTPVPASGQAAAYKQTKAQRARTMALYNPIPVRQNCFTVNR---SLFIFGEDNIVRKY 81 Query: 117 CISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFL 176 +++W PFE +IL TI ANC+ LA+ PEDD + LE+ E F+ IF EA + Sbjct: 82 AKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGI 141 Query: 177 KVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKAL 236 K++A G +FH +YLRNGWN++DFI+V+ G+ AT N D++ L Sbjct: 142 KIVALGFIFHKGSYLRNGWNVMDFIVVLSGIL------ATAGTHFNT------HVDLRTL 189 Query: 237 RAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHK 296 RA RVLRPL+LVSG+PSLQ+VL SI+KAMVPLL I LL+ F I+++AIIGLE + GK+H+ Sbjct: 190 RAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHR 249 Query: 297 TCY-NQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLT 355 C+ N GI + D P PC ++ C G CK W GP GIT FDN FA+LT Sbjct: 250 ACFMNNSGILE--GFDPPHPCGVQG-----CPAGYECKD-WIGPNDGITQFDNILFAVLT 301 Query: 356 VFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKA 415 VFQCITMEGWT VLY NDA+G W W+YF+ LIIIGSFFVLNLVLGVLSGEF+KERE+ Sbjct: 302 VFQCITMEGWTTVLYNTNDALGATWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERERV 361 Query: 416 KARGDFQKLREKQQLEEDLKGYLDWITQAEDI--DPENEDEGMDE-EKPRNMSMPTSETE 472 + R F KLR +QQ+E +L GY WI +AE++ EN++ G E R ++ S TE Sbjct: 362 ENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTE 421 Query: 473 SVNTENVAGGDIEGENCGARLAHRISKSKFS---RYWRRWNRFCRRKCRAAVKSNVFYWL 529 ++ ++ ++ + G LA KS Y+R R R R VKS VFYW+ Sbjct: 422 AMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRISIRHMVKSQVFYWI 481 Query: 530 VIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFN 589 V+ LV LNT +A H+NQP WLT + A L LF EM LKMY +G + YF S FN Sbjct: 482 VLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRLYFHSSFN 541 Query: 590 RFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVR 649 FD V G I E + + + GISVLR +RLLRIFKIT+YW SL NLV SL++S++ Sbjct: 542 CFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSSMK 601 Query: 650 SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWN 709 SI SLL LLFLFI++F+LLGMQLFGG+FNF++ T + FD FP +++TVFQILTGEDWN Sbjct: 602 SIISLLFLLFLFIVVFALLGMQLFGGRFNFND-GTPSANFDTFPAAIMTVFQILTGEDWN 660 Query: 710 SVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEE 769 VMY+GI + GG S GM IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EE Sbjct: 661 EVMYNGIRSQGGVS-SGMWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEE 719 Query: 770 EEEKERKKLARTASPEKKQELVEKPAVGESKEEK 803 EE +K + A P++ + + Sbjct: 720 EEAFNQKHALQKAKEVSPMSAPNMPSIERDRRRR 753 Score = 220 bits (561), Expect = 1e-56 Identities = 185/707 (26%), Positives = 329/707 (46%), Gaps = 124/707 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 ++K+Q K +K+ + A P ++ + NPIRRAC IV + FE+ ILL I A+ + Sbjct: 1112 EKKKQ---KKEKRETGKAMVPHSSMFIFSTTNPIRRACHYIVNLRYFEMCILLVIAASSI 1168 Query: 140 ALAIYIPFPEDDSNATNSNLERV----EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGW 195 ALA +D TNS +V +Y+F +FT E +K+I GL+ +Y R+ W Sbjct: 1169 ALAA------EDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKMIDQGLILQDGSYFRDLW 1222 Query: 196 NLLDFIIVVVGLFSAILEQATKADGANALG-GKGAGF-DVKALRAFRVLRPLRLVSGVPS 253 N+LDF++VV L + L ANALG KG +K+LR RVLRPL+ + +P Sbjct: 1223 NILDFVVVVGALVAFAL--------ANALGTNKGRDIKTIKSLRVLRVLRPLKTIKRLPK 1274 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 L+ V + ++ ++ + +I ++ + I+A+I ++LF GK C + ++D Sbjct: 1275 LKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFF-YCTDS-------SKDTE 1326 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 C G+ + + G + +H ++DN +A+LT+F T EGW VL Sbjct: 1327 KEC---IGNYVDHEKNKMEVKGREWKRHEF-HYDNIIWALLTLFTVSTGEGWPQVLQHSV 1382 Query: 374 DAVGRD---------WPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKL 424 D D I++V ++ FF +N+ + ++ F ++ GD K+ Sbjct: 1383 DVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KM 1433 Query: 425 REKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDI 484 E+ LE++ + +D+ A KP MP Sbjct: 1434 MEECSLEKNERACIDFAISA---------------KPLTRYMP----------------- 1461 Query: 485 EGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASE 544 +++ + +R W+ V S F + ++ ++ LNT+ + + Sbjct: 1462 --------------QNRHTFQYRVWH---------FVVSPSFEYTIMAMIALNTVVLMMK 1498 Query: 545 HYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETI 604 +Y+ P N A +F+ E +LK+ + G YF +N FD V G I E I Sbjct: 1499 YYSAPCTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEII 1558 Query: 605 LVETKIMSPLG--ISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFI 662 L ++K+++ G +S L+ R R+ K+ R ++ L+ + + S +++ + LL+ + Sbjct: 1559 LTDSKLVNTSGFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLF 1618 Query: 663 IIFSLLGMQLFGG-KFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG- 720 I++++GMQ+FG K + + R + F +F SL+ +F+ TGE W +M + G Sbjct: 1619 FIYAIIGMQVFGNIKLDEESHINRHNNFRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGC 1678 Query: 721 -----GPSFPGM-------LVCIYFIILFICGNYILLNVFLAIAVDN 755 PS L +YF+ ++++LN+F+A+ +DN Sbjct: 1679 EPDTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMDN 1725 Score = 194 bits (494), Expect = 6e-49 Identities = 174/715 (24%), Positives = 307/715 (42%), Gaps = 158/715 (22%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILGNA 936 + FIF +N R ++++ F +IL I+ + I LA E P + + L Sbjct: 68 SLFIFGEDNIVRKYAKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKT 127 Query: 937 DYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVV-SVSLISFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV S L + G + ++ Sbjct: 128 EPYFIGIFCFEAGIKIVALGFIFHKGSYLRNGWNVMDFIVVLSGILATAGTHFNTHVDLR 187 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ MFA IG++ + GKL Sbjct: 188 TLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKL 247 Query: 1056 YTCSDSSKQTEAECKGNYITYKDG-EVDHPI--------IQPRSW---ENSKFDFDNVLA 1103 + C N +G + HP + + W + FDN+L Sbjct: 248 HRA----------CFMNNSGILEGFDPPHPCGVQGCPAGYECKDWIGPNDGITQFDNILF 297 Query: 1104 AMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVG 1163 A++ +F T EGW +LY + D+ G +N+ ++FI III +FF++N+ +G Sbjct: 298 AVLTVFQCITMEGWTTVLYNTNDA----LGATWNW-----LYFIPLIIIGSFFVLNLVLG 348 Query: 1164 ------------------FVIVTFQEQGEQEYKNCEL----------------------- 1182 F+ + Q+Q E+E Sbjct: 349 VLSGEFAKERERVENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALE 408 Query: 1183 -----------------DKNQRQCVEYALKARPLRRYIPKN---------QHQYK----- 1211 D + CV+ + PL R K+ +H+ + Sbjct: 409 VLRRATIKRSRTEAMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRIS 468 Query: 1212 VWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLI 1271 + ++V S F +++ L+ LNT C+A+ H+ Q + LF GLF +EM LK+ Sbjct: 469 IRHMVKSQVFYWIVLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMY 528 Query: 1272 AFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEV 1331 P+ YF +N FDF + +GSI +V+ W F Sbjct: 529 GMGPRLYFHSSFNCFDFGVTVGSIFEVV-----------WAIF----------------- 560 Query: 1332 NNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIY 1391 + I+ R R++R+ K+ +R L+ + + S +++ + L+ + ++ Sbjct: 561 ---RPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFLFIVVF 617 Query: 1392 AVIGMQVF-GKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAP 1450 A++GMQ+F G+ ND T + NF TFP A++ +F+ TGE W ++M + Sbjct: 618 ALLGMQLFGGRFNFNDGTP---SANFDTFPAAIMTVFQILTGEDWNEVMYNGI------- 667 Query: 1451 ESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1502 ++G G ++ YFI + + ++N+F+A+ +DN LT+D Sbjct: 668 ------RSQGGVSSG-MWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 715 Score = 133 bits (335), Expect = 2e-30 Identities = 155/731 (21%), Positives = 302/731 (41%), Gaps = 140/731 (19%) Query: 526 FYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKA---LLALFTAEMLLKMYSLGL-- 580 F ++++ + N + +A E + + T + K + +F E +K+ +LG Sbjct: 91 FEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGIKIVALGFIF 150 Query: 581 --QAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLS 638 +Y + +N D VV GIL T T + + + LR VR+LR K+ SL Sbjct: 151 HKGSYLRNGWNVMDFIVVLSGILAT--AGTHFNTHVDLRTLRAVRVLRPLKLVSGIPSLQ 208 Query: 639 NLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFN-------------FDEMQTR 685 ++ S++ ++ + + LLLF I++F+++G++ + GK + FD Sbjct: 209 IVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHRACFMNNSGILEGFDPPHPC 268 Query: 686 R--------------------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP 725 + FDN ++LTVFQ +T E W +V+Y+ A G Sbjct: 269 GVQGCPAGYECKDWIGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTNDALGAT--- 325 Query: 726 GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE 785 +YFI L I G++ +LN+ L + A +E+ER + R Sbjct: 326 --WNWLYFIPLIIIGSFFVLNLVLGVLSGEFA-------------KERERVENRRAFMKL 370 Query: 786 KKQELVEKPAVGE----SKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPE 841 ++Q+ +E+ G K E++ L + + + ++ + E + Sbjct: 371 RRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTEAMT------ 424 Query: 842 TTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTI 901 + +E + + PL+ +K V + R+ +V + Sbjct: 425 ---RDSSDEHCVDISSVGTPLARASIKSAKVD----GVSYFRHKERLLRISIRHMVKSQV 477 Query: 902 FTNLILFFILLSSISLAAEDPVQHTS--FRNHILGNADYVFTSIFTLEIILKMTAYGAFL 959 F ++L + L++ +A V H + H+L A+++F +F LE+ LKM G L Sbjct: 478 FYWIVLSLVALNTACVAI---VHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRL 534 Query: 960 HKGSFCRNYFNILD--LLVVSVSLISFGIQSSAINV-VKILRVLRVLRPLRAINRAKGLK 1016 + + FN D + V S+ + + I + + +LR LR+LR + L+ Sbjct: 535 ----YFHSSFNCFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLR 590 Query: 1017 HVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITY 1076 ++V + ++++I +++ + L +FA +G+QLF G+ + Sbjct: 591 NLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGRF-------------------NF 631 Query: 1077 KDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIY 1136 DG +FD AA+M +F + T E W E++Y I S ++ Sbjct: 632 NDG-------------TPSANFDTFPAAIMTVFQILTGEDWNEVMYNGIRSQGGVSSGMW 678 Query: 1137 NYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEYKNCELDKNQRQ 1188 + +I+FI+ + + ++N+F+ + +T EQ E+E NQ+ Sbjct: 679 S-----AIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEE------AFNQKH 727 Query: 1189 CVEYALKARPL 1199 ++ A + P+ Sbjct: 728 ALQKAKEVSPM 738 Score = 81.3 bits (199), Expect = 1e-14 Identities = 72/302 (23%), Positives = 131/302 (43%), Gaps = 74/302 (24%) Query: 126 FEIIILLTIFANCVALAI-YIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 FE I+ I N V L + Y P A L+ + F ++F++E LKVIA+G L Sbjct: 1480 FEYTIMAMIALNTVVLMMKYYSAPCTYELA----LKYLNIAFTMVFSLECVLKVIAFGFL 1535 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DFI V+ + IL + + + GF++ L+ FR R Sbjct: 1536 ----NYFRDTWNIFDFITVIGSITEIILTDSKLVNTS--------GFNMSFLKLFRAARL 1583 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F Sbjct: 1584 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-------------- 1629 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 ++ ++ E+ R NF +F +++ +F+ T E Sbjct: 1630 GNIKLDE-------ESHINRH------------------NNFRSFFGSLMLLFRSATGEA 1664 Query: 365 WTDVLYWV------------------NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 W +++ N+ G D ++YFV+ I SF +LNL + V+ Sbjct: 1665 WQEIMLSCLGEKGCEPDTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMD 1724 Query: 407 EF 408 F Sbjct: 1725 NF 1726 >gi|111378393 sodium channel, voltage-gated, type VII, alpha [Homo sapiens] Length = 1682 Score = 404 bits (1039), Expect = e-112 Identities = 402/1596 (25%), Positives = 710/1596 (44%), Gaps = 256/1596 (16%) Query: 103 ALLC-LTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLER 161 ++LC L+ N IRR I ++ F++ IL+++ +CV +++ +NL + Sbjct: 96 SILCTLSPFNCIRRTTIKVLVHPFFQLFILISVLIDCVFMSL-------------TNLPK 142 Query: 162 ----VEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK 217 +E L I+T E +K+ A G+ ++L + WN LDF + V F I+ + Sbjct: 143 WRPVLENTLLGIYTFEILVKLFARGVWAGSFSFLGDPWNWLDFSVTV---FEVIIRYSPL 199 Query: 218 ADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLF 277 + L+ R LR L+++ L+ ++ +I + L+ + +L LF Sbjct: 200 DF-------------IPTLQTARTLRILKIIPLNQGLKSLVGVLIHCLKQLIGVIILTLF 246 Query: 278 VIIIYAIIGLELFMGKMHKTCYN--QEGIADVPAEDDPSP-------------------- 315 + I+++IG+ LFMG + C+ QE + +P Sbjct: 247 FLSIFSLIGMGLFMGNLKHKCFRWPQENENETLHNRTGNPYYIRETENFYYLEGERYALL 306 Query: 316 CALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYW-VND 374 C T G QC G VC P G TNFD+F +A+ +F+ + + + +VLY + Sbjct: 307 CGNRTDAG-QCPEGYVCVKAGINPDQGFTNFDSFGWALFALFRLMAQD-YPEVLYHQILY 364 Query: 375 AVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREK--QQLEE 432 A G+ + I+FV + + SF++ +L LG+L+ + +E+++ G+ K E QQ + Sbjct: 365 ASGKVY-MIFFVVVSFLFSFYMASLFLGILAMAYEEEKQRV---GEISKKIEPKFQQTGK 420 Query: 433 DLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGAR 492 +L+ EG + ++ + + + + ++T+ D+ E+ R Sbjct: 421 ELQ------------------EGNETDEAKTIQIEMKKRSPISTDTSL--DVL-EDATLR 459 Query: 493 LAHRISKSK---------FSRYWRRWNRF-CRRKCRAAVKSNVFY----WLVIFLVFLNT 538 + KSK F++ + WN C K + V + +I + LN Sbjct: 460 HKEELEKSKKICPLYWYKFAKTFLIWNCSPCWLKLKEFVHRIIMAPFTDLFLIICIILNV 519 Query: 539 LTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCG 598 + EHY + + N + +FTAEM+ K+ ++ YF +N FD +V Sbjct: 520 CFLTLEHYPMSKQTNTLLNIGNLVFIGIFTAEMIFKIIAMHPYGYFQVGWNIFDSMIVFH 579 Query: 599 GILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLL 658 G++E L G+++LR R+LRIFK+ +YW + L+ SL NS ++ L+LLL Sbjct: 580 GLIELCLANVA-----GMALLRLFRMLRIFKLGKYWPTFQILMWSLSNSWVALKDLVLLL 634 Query: 659 FLFIIIFSLLGMQLFGGKFNFDEM--------QTRRSTFDNFPQSLLTVFQILTGEDWNS 710 F FI + GM+LFG N++E Q R +F S L VF+IL GE W Sbjct: 635 FTFIFFSAAFGMKLFGK--NYEEFVCHIDKDCQLPRWHMHDFFHSFLNVFRILCGE-WVE 691 Query: 711 VMYDGIMAYGGPSFPGMLVCI-YFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEE 769 ++D M G S+ CI +++++ + GN ++L +FLA+ V + + + +T+ + E Sbjct: 692 TLWD-CMEVAGQSW-----CIPFYLMVILIGNLLVLYLFLAL-VSSFSSCKDVTAEENNE 744 Query: 770 EEEKER--------------KKLARTASPEK------KQELVEKPAVGESKEEKIELKSI 809 + + K L +T + K + V++ + E + Sbjct: 745 AKNLQLAVARIKKGINYVLLKILCKTQNVPKDTMDHVNEVYVKEDISDHTLSELSNTQDF 804 Query: 810 TADGESPPATKINMDDLQPNENEDKSPYPN-----PETTGEEDEE-------EPEMPVGP 857 D E T+ N + NE++ P P+ P +GE D E + + G Sbjct: 805 LKDKEKSSGTEKNATE---NESQSLIPSPSVSETVPIASGESDIENLDNKEIQSKSGDGG 861 Query: 858 RPRPLSELHLKEKA---VPMPEASAFFIFSSNNR-------------------------- 888 + + E + + + E F ++ Sbjct: 862 SKEKIKQSSSSECSTVDIAISEEEEMFYGGERSKHLKNGCRRGSSLGQISGASKKGKIWQ 921 Query: 889 -FRLQCHRIVNDTIFTNLILFFILLSSISLAAEDP-VQHTSFRNHILGNADYVFTSIFTL 946 R C +IV + F I LLS+ +LA ED + +L AD +FT IF L Sbjct: 922 NIRKTCCKIVENNWFKCFIGLVTLLSTGTLAFEDIYMDQRKTIKILLEYADMIFTYIFIL 981 Query: 947 EIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPL 1006 E++LK AYG K F ++ LD +VV V +S + +K L ++ LRPL Sbjct: 982 EMLLKWMAYG---FKAYFSNGWYR-LDFVVVIVFCLS--LIGKTREELKPLISMKFLRPL 1035 Query: 1007 RAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTE 1066 R +++ + +K VV+ + N+ +V ++ +F+ +GV LF G+ Y C D + + Sbjct: 1036 RVLSQFERMKVVVRALIKTTLPTLNVFLVCLMIWLIFSIMGVDLFAGRFYECIDPT--SG 1093 Query: 1067 AECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSID 1126 + + K + WEN+K +FDNV ++L V+TF GW ++ +ID Sbjct: 1094 ERFPSSEVMNKSRCESLLFNESMLWENAKMNFDNVGNGFLSLLQVATFNGWITIMNSAID 1153 Query: 1127 SHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQ-----GEQEYKNCE 1181 S + P + + + +FI +II F +++ + +I F + G + + Sbjct: 1154 SVAVNIQPHFEVNIYMYCYFINFIIFGVFLPLSMLITVIIDNFNKHKIKLGGSNIFITVK 1213 Query: 1182 LDKNQRQC--VEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239 K R+ + Y RP+ R P N+ Q ++ VV S F ++ VLI I + + Sbjct: 1214 QRKQYRRLKKLMYEDSQRPVPR--PLNKLQGFIFDVVTSQAFNVIVMVLICFQAIAMMID 1271 Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVI 1299 QS IA+ +N +F L+T+E ILKLIAF+ YF+ WN+FDF++VI SI + Sbjct: 1272 TDVQSLQMSIALYWINSIFVMLYTMECILKLIAFR-CFYFTIAWNIFDFMVVIFSITGLC 1330 Query: 1300 LSETNHYFCDAWNTFDALIVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSR 1359 L T VGS + + + +L + R++ +L Sbjct: 1331 LPMT----------------VGSYL---------------VPPSLVQLILLSRIIHMLRL 1359 Query: 1360 GEG---IRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNF 1416 G+G L+ + S AL + LLI ++ FIYAV GM F + IN +NF Sbjct: 1360 GKGPKVFHNLMLPLMLSLPALLNIILLIFLVMFIYAVFGMYNFAYV--KKEAGINDVSNF 1417 Query: 1417 QTFPQAVLLLFRCATGEAWQDIMLACMPGK--KCAPES-EPSNSTEGETPCGS-SFAVFY 1472 +TF ++L LF+ A W ++ A K C P+ P G+ CG+ S +FY Sbjct: 1418 ETFGNSMLCLFQVAIFAGWDGMLDAIFNSKWSDCDPDKINPGTQVRGD--CGNPSVGIFY 1475 Query: 1473 FISFYMLCAFLIINLFVAVIMDNFDYLTRDWS-ILGPHHLDEFKRIWAEYDPEAKGRIKH 1531 F+S+ ++ +I+N+++ V+M+ + ++ + L +F ++W +DP+ I Sbjct: 1476 FVSYILISWLIIVNMYIVVVMEFLNIASKKKNKTLSEDDFRKFFQVWKRFDPDRTQYIDS 1535 Query: 1532 LDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL 1567 + + PPL K P++ +L+++++P+ Sbjct: 1536 SKLSDFAAALDPPLFMAK--PNK---GQLIALDLPM 1566 Score = 145 bits (367), Expect = 3e-34 Identities = 158/712 (22%), Positives = 286/712 (40%), Gaps = 174/712 (24%) Query: 877 ASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED-PVQHTSFRNHILGN 935 AS S N R +++ F IL +L+ + ++ + P N +LG Sbjct: 95 ASILCTLSPFNCIRRTTIKVLVHPFFQLFILISVLIDCVFMSLTNLPKWRPVLENTLLG- 153 Query: 936 ADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVK 995 I+T EI++K+ A G + SF + +N LD SV++ I+ S ++ + Sbjct: 154 -------IYTFEILVKLFARGVWAGSFSFLGDPWNWLDF---SVTVFEVIIRYSPLDFIP 203 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 L+ R LR L+ I +GLK +V + ++ + ++I+T +F+ IG+ LF G L Sbjct: 204 TLQTARTLRILKIIPLNQGLKSLVGVLIHCLKQLIGVIILTLFFLSIFSLIGMGLFMGNL 263 Query: 1056 -YTCSDSSKQTEAECKGN------YIT------YKDGEVDHPIIQPR------------- 1089 + C ++ E E N YI Y +GE + R Sbjct: 264 KHKCFRWPQENENETLHNRTGNPYYIRETENFYYLEGERYALLCGNRTDAGQCPEGYVCV 323 Query: 1090 ----SWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIF 1145 + + +FD+ A+ ALF + + +PE+LY I G +Y IF Sbjct: 324 KAGINPDQGFTNFDSFGWALFALFRLMA-QDYPEVLYHQI---LYASGKVY------MIF 373 Query: 1146 FIIYIIIIAFFMMNIFVGFVIVTFQEQGEQ--------------------------EYKN 1179 F++ + +F+M ++F+G + + ++E+ ++ E K Sbjct: 374 FVVVSFLFSFYMASLFLGILAMAYEEEKQRVGEISKKIEPKFQQTGKELQEGNETDEAKT 433 Query: 1180 CELDKNQRQCV--------------------EYALKARPLRRYIPKNQHQYKVW------ 1213 +++ +R + E + K PL Y K + +W Sbjct: 434 IQIEMKKRSPISTDTSLDVLEDATLRHKEELEKSKKICPLYWY--KFAKTFLIWNCSPCW 491 Query: 1214 --------YVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVE 1265 ++ + + + + + I+LN L ++HY S +NI N++F G+FT E Sbjct: 492 LKLKEFVHRIIMAPFTDLFLIICIILNVCFLTLEHYPMSKQTNTLLNIGNLVFIGIFTAE 551 Query: 1266 MILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVD 1325 MI K+IA P GYF WN+FD +IV +I++ L+ Sbjct: 552 MIFKIIAMHPYGYFQVGWNIFDSMIVFHGLIELCLANV---------------------- 589 Query: 1326 IAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIV 1385 + RLFR++R+ KL + L+W+ S+ AL + LL+ Sbjct: 590 --------------AGMALLRLFRMLRIFKLGKYWPTFQILMWSLSNSWVALKDLVLLLF 635 Query: 1386 MLFFIYAVIGMQVFGKIALNDTTEINRNN-----NFQTFPQAVLLLFRCATGEAWQDIML 1440 F A GM++FGK I+++ + F + L +FR GE W + + Sbjct: 636 TFIFFSAAFGMKLFGKNYEEFVCHIDKDCQLPRWHMHDFFHSFLNVFRILCGE-WVETLW 694 Query: 1441 ACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVI 1492 CM G S+ + +++ ++ L++ LF+A++ Sbjct: 695 DCM------------------EVAGQSWCIPFYLMVILIGNLLVLYLFLALV 728 Score = 71.2 bits (173), Expect = 1e-11 Identities = 88/396 (22%), Positives = 161/396 (40%), Gaps = 97/396 (24%) Query: 74 STVSSTQRKRQQYGKPKKQGSTTATRP-PRALLCLTLKNPIRRACISIVEWKPFEIIILL 132 S + T ++R+QY + KK + RP PR L N ++ +V + F +I+++ Sbjct: 1206 SNIFITVKQRKQYRRLKKLMYEDSQRPVPRPL------NKLQGFIFDVVTSQAFNVIVMV 1259 Query: 133 TIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLR 192 I +A+ I + S + L + +F++++T+E LK+IA+ Y Sbjct: 1260 LICFQAIAMMIDT---DVQSLQMSIALYWINSIFVMLYTMECILKLIAFRCF-----YFT 1311 Query: 193 NGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVP 252 WN+ DF++V+ + L G+ + V+ + R++ LRL G Sbjct: 1312 IAWNIFDFMVVIFSITGLCLPMTV---GSYLVPPSL----VQLILLSRIIHMLRLGKGPK 1364 Query: 253 SLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDD 312 ++ ++ ++ LL+I LL+ V+ IYA+ G+ F + GI DV Sbjct: 1365 VFHNLMLPLMLSLPALLNIILLIFLVMFIYAVFGMYNF-----AYVKKEAGINDV----- 1414 Query: 313 PSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWV 372 +NF+ F +ML +FQ GW +L + Sbjct: 1415 -------------------------------SNFETFGNSMLCLFQVAIFAGWDGMLDAI 1443 Query: 373 ------------------------NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 N +VG YFV+ I+I ++N+ + V+ EF Sbjct: 1444 FNSKWSDCDPDKINPGTQVRGDCGNPSVG----IFYFVSYILISWLIIVNMYIVVVM-EF 1498 Query: 409 ----SKEREKAKARGDFQKLREK-QQLEEDLKGYLD 439 SK++ K + DF+K + ++ + D Y+D Sbjct: 1499 LNIASKKKNKTLSEDDFRKFFQVWKRFDPDRTQYID 1534 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.137 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,439,482 Number of Sequences: 37866 Number of extensions: 3972714 Number of successful extensions: 26232 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 125 Number of HSP's successfully gapped in prelim test: 260 Number of HSP's that attempted gapping in prelim test: 19343 Number of HSP's gapped (non-prelim): 2981 length of query: 2155 length of database: 18,247,518 effective HSP length: 118 effective length of query: 2037 effective length of database: 13,779,330 effective search space: 28068495210 effective search space used: 28068495210 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.