Search of human proteins with 193788732

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|193788732 calcium channel, voltage-dependent, L type, alpha
1C subunit isoform 5 [Homo sapiens]
         (2166 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|193788732 calcium channel, voltage-dependent, L type, alpha 1...  4337   0.0  
gi|193788724 calcium channel, voltage-dependent, L type, alpha 1...  4325   0.0  
gi|193788720 calcium channel, voltage-dependent, L type, alpha 1...  4308   0.0  
gi|193794830 calcium channel, voltage-dependent, L type, alpha 1...  4288   0.0  
gi|120433602 calcium channel, voltage-dependent, L type, alpha 1...  4266   0.0  
gi|193788528 calcium channel, voltage-dependent, L type, alpha 1...  4254   0.0  
gi|193788526 calcium channel, voltage-dependent, L type, alpha 1...  4254   0.0  
gi|193788540 calcium channel, voltage-dependent, L type, alpha 1...  4250   0.0  
gi|193788542 calcium channel, voltage-dependent, L type, alpha 1...  4249   0.0  
gi|193794828 calcium channel, voltage-dependent, L type, alpha 1...  4238   0.0  
gi|193788544 calcium channel, voltage-dependent, L type, alpha 1...  4238   0.0  
gi|193788530 calcium channel, voltage-dependent, L type, alpha 1...  4238   0.0  
gi|193788538 calcium channel, voltage-dependent, L type, alpha 1...  4234   0.0  
gi|193788730 calcium channel, voltage-dependent, L type, alpha 1...  4232   0.0  
gi|193788536 calcium channel, voltage-dependent, L type, alpha 1...  4232   0.0  
gi|193788728 calcium channel, voltage-dependent, L type, alpha 1...  4227   0.0  
gi|193788532 calcium channel, voltage-dependent, L type, alpha 1...  4221   0.0  
gi|193788548 calcium channel, voltage-dependent, L type, alpha 1...  4217   0.0  
gi|193794832 calcium channel, voltage-dependent, L type, alpha 1...  4217   0.0  
gi|193788534 calcium channel, voltage-dependent, L type, alpha 1...  4205   0.0  
gi|192807300 calcium channel, voltage-dependent, L type, alpha 1...  2734   0.0  
gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D ...  2734   0.0  
gi|192807298 calcium channel, voltage-dependent, L type, alpha 1...  2734   0.0  
gi|110349767 calcium channel, voltage-dependent, L type, alpha 1...  2299   0.0  
gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F...  2269   0.0  
gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s...   761   0.0  
gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s...   753   0.0  
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ...   753   0.0  
gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E...   732   0.0  
gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo s...   323   9e-88

>gi|193788732 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 5 [Homo sapiens]
          Length = 2166

 Score = 4337 bits (11249), Expect = 0.0
 Identities = 2166/2166 (100%), Positives = 2166/2166 (100%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
Sbjct: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620

Query: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680
            WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
Sbjct: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680

Query: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740
            AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
Sbjct: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740

Query: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800
            DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
Sbjct: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800

Query: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860
            TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS
Sbjct: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860

Query: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920
            QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS
Sbjct: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920

Query: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980
            LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF
Sbjct: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980

Query: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040
            ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR
Sbjct: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040

Query: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100
            PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE
Sbjct: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100

Query: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160
            EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR
Sbjct: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160

Query: 2161 VYVSSL 2166
            VYVSSL
Sbjct: 2161 VYVSSL 2166


>gi|193788724 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 2 [Homo sapiens]
          Length = 2186

 Score = 4325 bits (11218), Expect = 0.0
 Identities = 2166/2186 (99%), Positives = 2166/2186 (99%), Gaps = 20/2186 (0%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK--------- 951
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK         
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960

Query: 952  -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000
                       MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
Sbjct: 961  TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020

Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060
            RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080

Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120
            SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140

Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180
            LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200

Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240
            ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260

Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1300
            YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1320

Query: 1301 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1360
            SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
Sbjct: 1321 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1380

Query: 1361 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1420
            VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
Sbjct: 1381 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1440

Query: 1421 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1480
            INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
Sbjct: 1441 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1500

Query: 1481 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1540
            VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
Sbjct: 1501 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1560

Query: 1541 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1600
            KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
Sbjct: 1561 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1620

Query: 1601 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1660
            KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
Sbjct: 1621 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1680

Query: 1661 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1720
            KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
Sbjct: 1681 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1740

Query: 1721 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1780
            DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
Sbjct: 1741 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1800

Query: 1781 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1840
            FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
Sbjct: 1801 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1860

Query: 1841 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP 1900
            SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
Sbjct: 1861 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP 1920

Query: 1901 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV 1960
            EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
Sbjct: 1921 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV 1980

Query: 1961 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC 2020
            AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
Sbjct: 1981 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC 2040

Query: 2021 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD 2080
            GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
Sbjct: 2041 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD 2100

Query: 2081 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE 2140
            PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
Sbjct: 2101 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE 2160

Query: 2141 DAGCVRARGRPSEEELQDSRVYVSSL 2166
            DAGCVRARGRPSEEELQDSRVYVSSL
Sbjct: 2161 DAGCVRARGRPSEEELQDSRVYVSSL 2186


>gi|193788720 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 1 [Homo sapiens]
          Length = 2221

 Score = 4308 bits (11172), Expect = 0.0
 Identities = 2166/2221 (97%), Positives = 2166/2221 (97%), Gaps = 55/2221 (2%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA----------- 949
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA           
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960

Query: 950  ---------LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000
                     LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
Sbjct: 961  TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020

Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060
            RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080

Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120
            SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140

Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180
            LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200

Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240
            ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260

Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1300
            YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1320

Query: 1301 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1360
            SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
Sbjct: 1321 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1380

Query: 1361 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1420
            VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
Sbjct: 1381 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1440

Query: 1421 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1480
            INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
Sbjct: 1441 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1500

Query: 1481 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1540
            VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
Sbjct: 1501 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1560

Query: 1541 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1600
            KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
Sbjct: 1561 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1620

Query: 1601 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1660
            KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
Sbjct: 1621 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1680

Query: 1661 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1720
            KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
Sbjct: 1681 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1740

Query: 1721 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1780
            DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
Sbjct: 1741 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1800

Query: 1781 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1840
            FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
Sbjct: 1801 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1860

Query: 1841 SN-----------------------------------RCHSRESQAAMAGQEETSQDETY 1865
            SN                                   RCHSRESQAAMAGQEETSQDETY
Sbjct: 1861 SNRERHVPMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETY 1920

Query: 1866 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA 1925
            EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA
Sbjct: 1921 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA 1980

Query: 1926 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA 1985
            SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA
Sbjct: 1981 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA 2040

Query: 1986 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM 2045
            TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM
Sbjct: 2041 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM 2100

Query: 2046 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA 2105
            VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA
Sbjct: 2101 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA 2160

Query: 2106 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS 2165
            ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS
Sbjct: 2161 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS 2220

Query: 2166 L 2166
            L
Sbjct: 2221 L 2221


>gi|193794830 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 10 [Homo sapiens]
          Length = 2155

 Score = 4288 bits (11122), Expect = 0.0
 Identities = 2148/2166 (99%), Positives = 2150/2166 (99%), Gaps = 11/2166 (0%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL   D VFT+IFT+EI LKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVN           NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1321 GSIVDIAITEVN-----------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1369

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1370 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1429

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1430 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1489

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1490 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1549

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
Sbjct: 1550 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1609

Query: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680
            WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
Sbjct: 1610 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1669

Query: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740
            AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
Sbjct: 1670 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1729

Query: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800
            DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
Sbjct: 1730 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1789

Query: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860
            TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS
Sbjct: 1790 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1849

Query: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920
            QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS
Sbjct: 1850 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1909

Query: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980
            LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF
Sbjct: 1910 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1969

Query: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040
            ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR
Sbjct: 1970 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2029

Query: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100
            PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE
Sbjct: 2030 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2089

Query: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160
            EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR
Sbjct: 2090 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2149

Query: 2161 VYVSSL 2166
            VYVSSL
Sbjct: 2150 VYVSSL 2155


>gi|120433602 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 18 [Homo sapiens]
          Length = 2138

 Score = 4266 bits (11063), Expect = 0.0
 Identities = 2138/2166 (98%), Positives = 2138/2166 (98%), Gaps = 28/2166 (1%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK                            HYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
Sbjct: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1592

Query: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680
            WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
Sbjct: 1593 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652

Query: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740
            AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
Sbjct: 1653 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1712

Query: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800
            DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
Sbjct: 1713 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1772

Query: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860
            TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS
Sbjct: 1773 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1832

Query: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920
            QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS
Sbjct: 1833 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1892

Query: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980
            LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF
Sbjct: 1893 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1952

Query: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040
            ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR
Sbjct: 1953 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2012

Query: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100
            PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE
Sbjct: 2013 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2072

Query: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160
            EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR
Sbjct: 2073 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2132

Query: 2161 VYVSSL 2166
            VYVSSL
Sbjct: 2133 VYVSSL 2138


>gi|193788528 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 8 [Homo sapiens]
          Length = 2157

 Score = 4254 bits (11033), Expect = 0.0
 Identities = 2138/2185 (97%), Positives = 2138/2185 (97%), Gaps = 47/2185 (2%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK                            HYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE----------------- 1603
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE                 
Sbjct: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFR 1592

Query: 1604 --GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1661
              GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK
Sbjct: 1593 PAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1652

Query: 1662 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1721
            RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED
Sbjct: 1653 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1712

Query: 1722 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1781
            DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF
Sbjct: 1713 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1772

Query: 1782 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1841
            TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS
Sbjct: 1773 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1832

Query: 1842 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1901
            NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE
Sbjct: 1833 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1892

Query: 1902 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1961
            EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA
Sbjct: 1893 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1952

Query: 1962 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2021
            GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG
Sbjct: 1953 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2012

Query: 2022 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2081
            SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP
Sbjct: 2013 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2072

Query: 2082 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2141
            KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED
Sbjct: 2073 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2132

Query: 2142 AGCVRARGRPSEEELQDSRVYVSSL 2166
            AGCVRARGRPSEEELQDSRVYVSSL
Sbjct: 2133 AGCVRARGRPSEEELQDSRVYVSSL 2157


>gi|193788526 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 6 [Homo sapiens]
          Length = 2158

 Score = 4254 bits (11032), Expect = 0.0
 Identities = 2138/2186 (97%), Positives = 2138/2186 (97%), Gaps = 48/2186 (2%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK--------- 951
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK         
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960

Query: 952  -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000
                       MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
Sbjct: 961  TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020

Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060
            RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080

Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120
            SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140

Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180
            LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200

Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240
            ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260

Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1300
            YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK                        
Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------ 1296

Query: 1301 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1360
                HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
Sbjct: 1297 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1352

Query: 1361 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1420
            VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
Sbjct: 1353 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1412

Query: 1421 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1480
            INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
Sbjct: 1413 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1472

Query: 1481 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1540
            VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
Sbjct: 1473 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1532

Query: 1541 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1600
            KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
Sbjct: 1533 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1592

Query: 1601 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1660
            KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
Sbjct: 1593 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1652

Query: 1661 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1720
            KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
Sbjct: 1653 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1712

Query: 1721 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1780
            DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
Sbjct: 1713 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1772

Query: 1781 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1840
            FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
Sbjct: 1773 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1832

Query: 1841 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP 1900
            SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
Sbjct: 1833 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP 1892

Query: 1901 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV 1960
            EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
Sbjct: 1893 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV 1952

Query: 1961 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC 2020
            AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
Sbjct: 1953 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC 2012

Query: 2021 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD 2080
            GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
Sbjct: 2013 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD 2072

Query: 2081 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE 2140
            PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
Sbjct: 2073 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE 2132

Query: 2141 DAGCVRARGRPSEEELQDSRVYVSSL 2166
            DAGCVRARGRPSEEELQDSRVYVSSL
Sbjct: 2133 DAGCVRARGRPSEEELQDSRVYVSSL 2158


>gi|193788540 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 16 [Homo sapiens]
          Length = 2138

 Score = 4250 bits (11022), Expect = 0.0
 Identities = 2128/2166 (98%), Positives = 2133/2166 (98%), Gaps = 28/2166 (1%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPKGYFS                            D WN FD LIV+
Sbjct: 1261 LFTVEMILKLIAFKPKGYFS----------------------------DPWNVFDFLIVI 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSI+D+ ++E NPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
Sbjct: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1592

Query: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680
            WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
Sbjct: 1593 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652

Query: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740
            AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
Sbjct: 1653 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1712

Query: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800
            DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
Sbjct: 1713 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1772

Query: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860
            TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS
Sbjct: 1773 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1832

Query: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920
            QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS
Sbjct: 1833 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1892

Query: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980
            LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF
Sbjct: 1893 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1952

Query: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040
            ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR
Sbjct: 1953 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2012

Query: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100
            PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE
Sbjct: 2013 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2072

Query: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160
            EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR
Sbjct: 2073 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2132

Query: 2161 VYVSSL 2166
            VYVSSL
Sbjct: 2133 VYVSSL 2138


>gi|193788542 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 17 [Homo sapiens]
          Length = 2138

 Score = 4249 bits (11021), Expect = 0.0
 Identities = 2131/2166 (98%), Positives = 2133/2166 (98%), Gaps = 28/2166 (1%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL   D VFT+IFT+EI LKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK                            HYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
Sbjct: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1592

Query: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680
            WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
Sbjct: 1593 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652

Query: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740
            AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
Sbjct: 1653 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1712

Query: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800
            DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
Sbjct: 1713 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1772

Query: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860
            TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS
Sbjct: 1773 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1832

Query: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920
            QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS
Sbjct: 1833 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1892

Query: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980
            LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF
Sbjct: 1893 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1952

Query: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040
            ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR
Sbjct: 1953 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2012

Query: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100
            PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE
Sbjct: 2013 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2072

Query: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160
            EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR
Sbjct: 2073 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2132

Query: 2161 VYVSSL 2166
            VYVSSL
Sbjct: 2133 VYVSSL 2138


>gi|193794828 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 7 [Homo sapiens]
          Length = 2157

 Score = 4238 bits (10992), Expect = 0.0
 Identities = 2128/2185 (97%), Positives = 2133/2185 (97%), Gaps = 47/2185 (2%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPKGYFS                            D WN FD LIV+
Sbjct: 1261 LFTVEMILKLIAFKPKGYFS----------------------------DPWNVFDFLIVI 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSI+D+ ++E NPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE----------------- 1603
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE                 
Sbjct: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFR 1592

Query: 1604 --GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1661
              GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK
Sbjct: 1593 PAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1652

Query: 1662 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1721
            RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED
Sbjct: 1653 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1712

Query: 1722 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1781
            DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF
Sbjct: 1713 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1772

Query: 1782 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1841
            TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS
Sbjct: 1773 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1832

Query: 1842 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1901
            NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE
Sbjct: 1833 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1892

Query: 1902 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1961
            EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA
Sbjct: 1893 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1952

Query: 1962 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2021
            GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG
Sbjct: 1953 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2012

Query: 2022 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2081
            SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP
Sbjct: 2013 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2072

Query: 2082 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2141
            KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED
Sbjct: 2073 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2132

Query: 2142 AGCVRARGRPSEEELQDSRVYVSSL 2166
            AGCVRARGRPSEEELQDSRVYVSSL
Sbjct: 2133 AGCVRARGRPSEEELQDSRVYVSSL 2157


>gi|193788544 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 19 [Homo sapiens]
          Length = 2135

 Score = 4238 bits (10991), Expect = 0.0
 Identities = 2125/2166 (98%), Positives = 2130/2166 (98%), Gaps = 31/2166 (1%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIA   AEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIA---AEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 357

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 358  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 417

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 418  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 477

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 478  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 537

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 538  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 597

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 598  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 657

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 658  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 717

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 718  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 777

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 778  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 837

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 838  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 897

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
Sbjct: 898  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 957

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 958  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1017

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1018 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1077

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1078 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1137

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1138 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1197

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1198 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1257

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPKGYFS                            D WN FD LIV+
Sbjct: 1258 LFTVEMILKLIAFKPKGYFS----------------------------DPWNVFDFLIVI 1289

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSI+D+ ++E NPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1290 GSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1349

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1350 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1409

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1410 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1469

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1470 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1529

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
Sbjct: 1530 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1589

Query: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680
            WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
Sbjct: 1590 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1649

Query: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740
            AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
Sbjct: 1650 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1709

Query: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800
            DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
Sbjct: 1710 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1769

Query: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860
            TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS
Sbjct: 1770 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1829

Query: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920
            QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS
Sbjct: 1830 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1889

Query: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980
            LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF
Sbjct: 1890 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1949

Query: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040
            ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR
Sbjct: 1950 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2009

Query: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100
            PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE
Sbjct: 2010 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2069

Query: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160
            EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR
Sbjct: 2070 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2129

Query: 2161 VYVSSL 2166
            VYVSSL
Sbjct: 2130 VYVSSL 2135


>gi|193788530 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 9 [Homo sapiens]
          Length = 2157

 Score = 4238 bits (10991), Expect = 0.0
 Identities = 2131/2185 (97%), Positives = 2133/2185 (97%), Gaps = 47/2185 (2%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL   D VFT+IFT+EI LKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK                            HYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE----------------- 1603
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE                 
Sbjct: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFR 1592

Query: 1604 --GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1661
              GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK
Sbjct: 1593 PAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1652

Query: 1662 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1721
            RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED
Sbjct: 1653 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1712

Query: 1722 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1781
            DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF
Sbjct: 1713 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1772

Query: 1782 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1841
            TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS
Sbjct: 1773 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1832

Query: 1842 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1901
            NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE
Sbjct: 1833 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1892

Query: 1902 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1961
            EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA
Sbjct: 1893 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1952

Query: 1962 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2021
            GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG
Sbjct: 1953 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2012

Query: 2022 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2081
            SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP
Sbjct: 2013 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2072

Query: 2082 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2141
            KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED
Sbjct: 2073 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2132

Query: 2142 AGCVRARGRPSEEELQDSRVYVSSL 2166
            AGCVRARGRPSEEELQDSRVYVSSL
Sbjct: 2133 AGCVRARGRPSEEELQDSRVYVSSL 2157


>gi|193788538 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 15 [Homo sapiens]
          Length = 2138

 Score = 4234 bits (10980), Expect = 0.0
 Identities = 2121/2166 (97%), Positives = 2128/2166 (98%), Gaps = 28/2166 (1%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL   D VFT+IFT+EI LKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPKGYFS                            D WN FD LIV+
Sbjct: 1261 LFTVEMILKLIAFKPKGYFS----------------------------DPWNVFDFLIVI 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSI+D+ ++E NPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
Sbjct: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1592

Query: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680
            WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
Sbjct: 1593 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652

Query: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740
            AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
Sbjct: 1653 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1712

Query: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800
            DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
Sbjct: 1713 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1772

Query: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860
            TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS
Sbjct: 1773 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1832

Query: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920
            QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS
Sbjct: 1833 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1892

Query: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980
            LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF
Sbjct: 1893 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1952

Query: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040
            ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR
Sbjct: 1953 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2012

Query: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100
            PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE
Sbjct: 2013 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2072

Query: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160
            EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR
Sbjct: 2073 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2132

Query: 2161 VYVSSL 2166
            VYVSSL
Sbjct: 2133 VYVSSL 2138


>gi|193788730 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 4 [Homo sapiens]
          Length = 2173

 Score = 4232 bits (10975), Expect = 0.0
 Identities = 2131/2201 (96%), Positives = 2133/2201 (96%), Gaps = 63/2201 (2%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL   D VFT+IFT+EI LKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK                            HYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
Sbjct: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1592

Query: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680
            WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
Sbjct: 1593 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652

Query: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740
            AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
Sbjct: 1653 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1712

Query: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800
            DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
Sbjct: 1713 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1772

Query: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSN------------------ 1842
            TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSN                  
Sbjct: 1773 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRERHVPMCEDLELRRDSG 1832

Query: 1843 -----------------RCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTE 1885
                             RCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTE
Sbjct: 1833 SAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTE 1892

Query: 1886 MLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQK 1945
            MLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQK
Sbjct: 1893 MLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQK 1952

Query: 1946 TVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGV 2005
            TVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGV
Sbjct: 1953 TVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGV 2012

Query: 2006 ESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLV 2065
            ESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLV
Sbjct: 2013 ESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLV 2072

Query: 2066 EAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPF 2125
            EAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPF
Sbjct: 2073 EAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPF 2132

Query: 2126 VNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2166
            VNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
Sbjct: 2133 VNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2173


>gi|193788536 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 14 [Homo sapiens]
          Length = 2138

 Score = 4232 bits (10975), Expect = 0.0
 Identities = 2121/2166 (97%), Positives = 2129/2166 (98%), Gaps = 28/2166 (1%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYW+ DA+G + PW+YFV+L+I GSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL   D VFT+IFT+EI LKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK                            HYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
Sbjct: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1592

Query: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680
            WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
Sbjct: 1593 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652

Query: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740
            AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
Sbjct: 1653 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1712

Query: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800
            DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
Sbjct: 1713 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1772

Query: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860
            TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS
Sbjct: 1773 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1832

Query: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920
            QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS
Sbjct: 1833 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1892

Query: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980
            LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF
Sbjct: 1893 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1952

Query: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040
            ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR
Sbjct: 1953 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2012

Query: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100
            PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE
Sbjct: 2013 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2072

Query: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160
            EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR
Sbjct: 2073 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2132

Query: 2161 VYVSSL 2166
            VYVSSL
Sbjct: 2133 VYVSSL 2138


>gi|193788728 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 3 [Homo sapiens]
          Length = 2179

 Score = 4227 bits (10963), Expect = 0.0
 Identities = 2132/2207 (96%), Positives = 2133/2207 (96%), Gaps = 69/2207 (3%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK YF D WN FD LIV+GSI                         
Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSI------------------------- 1295

Query: 1321 GSIVDIAITEVNPAEHTQCSPSM----------------------NAEENSRISITFFRL 1358
               VDIAITEVNPAEHTQCSPSM                      NAEENSRISITFFRL
Sbjct: 1296 ---VDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRL 1352

Query: 1359 FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT 1418
            FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT
Sbjct: 1353 FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT 1412

Query: 1419 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS 1478
            TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS
Sbjct: 1413 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS 1472

Query: 1479 FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG 1538
            FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG
Sbjct: 1473 FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG 1532

Query: 1539 RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL 1598
            RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL
Sbjct: 1533 RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL 1592

Query: 1599 RIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDD 1639
            RIKTE                   GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDD
Sbjct: 1593 RIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDD 1652

Query: 1640 EVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISG 1699
            EVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISG
Sbjct: 1653 EVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISG 1712

Query: 1700 DLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHIN 1759
            DLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHIN
Sbjct: 1713 DLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHIN 1772

Query: 1760 KAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTV 1819
            KAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTV
Sbjct: 1773 KAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTV 1832

Query: 1820 EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEP 1879
            EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEP
Sbjct: 1833 EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEP 1892

Query: 1880 SLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRG 1939
            SLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRG
Sbjct: 1893 SLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRG 1952

Query: 1940 GDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPT 1999
            GDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPT
Sbjct: 1953 GDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPT 2012

Query: 2000 LRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHG 2059
            LRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHG
Sbjct: 2013 LRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHG 2072

Query: 2060 SASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPN 2119
            SASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPN
Sbjct: 2073 SASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPN 2132

Query: 2120 GALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2166
            GALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
Sbjct: 2133 GALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2179


>gi|193788532 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 11 [Homo sapiens]
          Length = 2146

 Score = 4221 bits (10948), Expect = 0.0
 Identities = 2127/2185 (97%), Positives = 2127/2185 (97%), Gaps = 58/2185 (2%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK                            HYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVN           NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIVDIAITEVN-----------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1341

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1342 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1401

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1402 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1461

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1462 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1521

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE----------------- 1603
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE                 
Sbjct: 1522 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFR 1581

Query: 1604 --GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1661
              GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK
Sbjct: 1582 PAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1641

Query: 1662 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1721
            RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED
Sbjct: 1642 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1701

Query: 1722 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1781
            DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF
Sbjct: 1702 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1761

Query: 1782 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1841
            TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS
Sbjct: 1762 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1821

Query: 1842 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1901
            NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE
Sbjct: 1822 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1881

Query: 1902 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1961
            EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA
Sbjct: 1882 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1941

Query: 1962 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2021
            GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG
Sbjct: 1942 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2001

Query: 2022 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2081
            SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP
Sbjct: 2002 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2061

Query: 2082 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2141
            KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED
Sbjct: 2062 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2121

Query: 2142 AGCVRARGRPSEEELQDSRVYVSSL 2166
            AGCVRARGRPSEEELQDSRVYVSSL
Sbjct: 2122 AGCVRARGRPSEEELQDSRVYVSSL 2146


>gi|193788548 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 20 [Homo sapiens]
          Length = 2127

 Score = 4217 bits (10936), Expect = 0.0
 Identities = 2120/2166 (97%), Positives = 2122/2166 (97%), Gaps = 39/2166 (1%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL   D VFT+IFT+EI LKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK                            HYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVN           NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIVDIAITEVN-----------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1341

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1342 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1401

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1402 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1461

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1462 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1521

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI
Sbjct: 1522 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1581

Query: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680
            WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ
Sbjct: 1582 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1641

Query: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740
            AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS
Sbjct: 1642 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1701

Query: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800
            DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN
Sbjct: 1702 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1761

Query: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860
            TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS
Sbjct: 1762 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1821

Query: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920
            QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS
Sbjct: 1822 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1881

Query: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980
            LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF
Sbjct: 1882 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1941

Query: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040
            ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR
Sbjct: 1942 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2001

Query: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100
            PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE
Sbjct: 2002 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2061

Query: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160
            EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR
Sbjct: 2062 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2121

Query: 2161 VYVSSL 2166
            VYVSSL
Sbjct: 2122 VYVSSL 2127


>gi|193794832 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoforom 13 [Homo sapiens]
          Length = 2144

 Score = 4217 bits (10936), Expect = 0.0
 Identities = 2125/2185 (97%), Positives = 2125/2185 (97%), Gaps = 60/2185 (2%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK                            HYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITE             NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIVDIAITE-------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1339

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1340 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1399

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1400 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1459

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1460 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1519

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE----------------- 1603
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE                 
Sbjct: 1520 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFR 1579

Query: 1604 --GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1661
              GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK
Sbjct: 1580 PAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1639

Query: 1662 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1721
            RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED
Sbjct: 1640 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1699

Query: 1722 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1781
            DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF
Sbjct: 1700 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1759

Query: 1782 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1841
            TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS
Sbjct: 1760 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1819

Query: 1842 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1901
            NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE
Sbjct: 1820 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1879

Query: 1902 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1961
            EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA
Sbjct: 1880 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1939

Query: 1962 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2021
            GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG
Sbjct: 1940 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 1999

Query: 2022 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2081
            SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP
Sbjct: 2000 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2059

Query: 2082 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2141
            KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED
Sbjct: 2060 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2119

Query: 2142 AGCVRARGRPSEEELQDSRVYVSSL 2166
            AGCVRARGRPSEEELQDSRVYVSSL
Sbjct: 2120 AGCVRARGRPSEEELQDSRVYVSSL 2144


>gi|193788534 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 12 [Homo sapiens]
          Length = 2146

 Score = 4205 bits (10906), Expect = 0.0
 Identities = 2120/2185 (97%), Positives = 2122/2185 (97%), Gaps = 58/2185 (2%)

Query: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60
            MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
Sbjct: 1    MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60

Query: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120
            QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
Sbjct: 61   QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120

Query: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180
            VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
Sbjct: 121  VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180

Query: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240
            YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
Sbjct: 181  YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240

Query: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300
            VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
Sbjct: 241  VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300

Query: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360
            QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
Sbjct: 301  QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360

Query: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420
            TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
Sbjct: 361  TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420

Query: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480
            FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
Sbjct: 421  FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480

Query: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540
            GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
Sbjct: 481  GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540

Query: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600
            IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
Sbjct: 541  IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600

Query: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660
            LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
Sbjct: 601  LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660

Query: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720
            FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
Sbjct: 661  FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720

Query: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780
            GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
Sbjct: 721  GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780

Query: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840
            TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
Sbjct: 781  TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840

Query: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900
            ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
Sbjct: 841  ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900

Query: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960
            IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL   D VFT+IFT+EI LKMTAYGAFLH
Sbjct: 901  IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960

Query: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020
            KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
Sbjct: 961  KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020

Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080
            CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080

Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140
            VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV
Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140

Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200
            EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200

Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260
            RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260

Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320
            LFTVEMILKLIAFKPK                            HYFCDAWNTFDALIVV
Sbjct: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292

Query: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380
            GSIVDIAITEVN           NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT
Sbjct: 1293 GSIVDIAITEVN-----------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1341

Query: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440
            FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC
Sbjct: 1342 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1401

Query: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500
            ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV
Sbjct: 1402 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1461

Query: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560
            AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK
Sbjct: 1462 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1521

Query: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE----------------- 1603
            LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE                 
Sbjct: 1522 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFR 1581

Query: 1604 --GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1661
              GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK
Sbjct: 1582 PAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKK 1641

Query: 1662 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1721
            RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED
Sbjct: 1642 RKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASED 1701

Query: 1722 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1781
            DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF
Sbjct: 1702 DIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTF 1761

Query: 1782 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1841
            TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS
Sbjct: 1762 TPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSS 1821

Query: 1842 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1901
            NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE
Sbjct: 1822 NRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPE 1881

Query: 1902 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1961
            EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA
Sbjct: 1882 EDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVA 1941

Query: 1962 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2021
            GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG
Sbjct: 1942 GLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCG 2001

Query: 2022 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2081
            SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP
Sbjct: 2002 SWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDP 2061

Query: 2082 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2141
            KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED
Sbjct: 2062 KFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEED 2121

Query: 2142 AGCVRARGRPSEEELQDSRVYVSSL 2166
            AGCVRARGRPSEEELQDSRVYVSSL
Sbjct: 2122 AGCVRARGRPSEEELQDSRVYVSSL 2146


>gi|192807300 calcium channel, voltage-dependent, L type, alpha 1D
            subunit isoform b [Homo sapiens]
          Length = 2161

 Score = 2734 bits (7087), Expect = 0.0
 Identities = 1458/2181 (66%), Positives = 1663/2181 (76%), Gaps = 134/2181 (6%)

Query: 50   LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108
            LSWQAAIDAARQAK   +   +    V S +QRKRQQY K KKQG+++ +RP RAL CL+
Sbjct: 51   LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110

Query: 109  LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168
            L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI
Sbjct: 111  LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170

Query: 169  IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227
            IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK  +G N   GK
Sbjct: 171  IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230

Query: 228  GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287
              GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL
Sbjct: 231  SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290

Query: 288  ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346
            ELF+GKMHKTC+  +  +D+ AE+DP+PCA  +G+GRQC  NGT C+ GW GP  GITNF
Sbjct: 291  ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347

Query: 347  DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406
            DNFAFAMLTVFQCITMEGWTDVLYW+NDA+G + PW+YFV+L+I GSFFVLNLVLGVLSG
Sbjct: 348  DNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSG 407

Query: 407  EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466
            EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM
Sbjct: 408  EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466

Query: 467  PTSETESVNTENVAGGDIEGEN--CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524
            PTSETESVNTENV+G   EGEN  C   L   ISKSK SR WRRWNRF RR+CRAAVKS 
Sbjct: 467  PTSETESVNTENVSG---EGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSV 523

Query: 525  VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584
             FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LLALFT EML+KMYSLGLQAYF
Sbjct: 524  TFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYF 583

Query: 585  VSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASL 644
            VSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRLLRIFK+TR+W SLSNLVASL
Sbjct: 584  VSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASL 643

Query: 645  LNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILT 704
            LNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT+RSTFDNFPQ+LLTVFQILT
Sbjct: 644  LNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILT 703

Query: 705  GEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764
            GEDWN+VMYDGIMAYGGPS  GM+VCIYFIILFICGNYILLNVFLAIAVDNLADAESL +
Sbjct: 704  GEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNT 763

Query: 765  AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMD 824
            AQKEE EEKERKK+AR  S E K+    KP V +                     K+ +D
Sbjct: 764  AQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD---------------NKVTID 806

Query: 825  DLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASA 879
            D +  E+EDK PYP       E   EE+E+EPE+P GPRPR +SEL++KEK  P+PE SA
Sbjct: 807  DYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSA 865

Query: 880  FFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIV 939
            FFI S  N  R+ CH+++N  IFTNLIL FI+LSS +LAAEDP++  SFRN IL YFD  
Sbjct: 866  FFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYA 925

Query: 940  FTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRV 999
            FT IFT+EI LKMT +GAFLHKG+FCRNYFN+LD+LVV VSL+SFGIQSSAI+VVKILRV
Sbjct: 926  FTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRV 985

Query: 1000 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS 1059
            LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Y C+
Sbjct: 986  LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCT 1045

Query: 1060 DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE 1119
            D +K    EC+G +I YKDG+VD P+++ R W+NS F+FDNVL+AMMALFTVSTFEGWP 
Sbjct: 1046 DEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPA 1105

Query: 1120 LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN 1179
            LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMNIFVGFVIVTFQEQGE+EYKN
Sbjct: 1106 LLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKN 1165

Query: 1180 CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239
            CELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ FEY+MFVLI+LNT+CLAMQ
Sbjct: 1166 CELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQ 1225

Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVI 1299
            HY QS +F  AM+ILNM+FTG+FTVEM+LK+IAFKPKGYFSD WN FD LIVIGSIIDV 
Sbjct: 1226 HYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVA 1285

Query: 1300 LSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLF 1359
            LSE +                        TE         +P  N+EE++RISITFFRLF
Sbjct: 1286 LSEADP-----------------------TESENVPVPTATPG-NSEESNRISITFFRLF 1321

Query: 1360 RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTT 1419
            RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLI MLFFIYAVIGMQ+FGK+A+ D  
Sbjct: 1322 RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNN 1381

Query: 1420 EINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSF 1479
            +INRNNNFQTFPQAVLLLFRCATGEAWQ+IMLAC+PGK C PES+ +     E  CGS+F
Sbjct: 1382 QINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGE--EYTCGSNF 1439

Query: 1480 AVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGR 1539
            A+ YFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDPEAKGR
Sbjct: 1440 AIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGR 1499

Query: 1540 IKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALR 1599
            IKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTVMFNATLFALVRTAL+
Sbjct: 1500 IKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALK 1559

Query: 1600 IKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKF 1659
            IKTEGNLEQANEELRA+IKKIWK+TSMKLLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKF
Sbjct: 1560 IKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKF 1619

Query: 1660 KKRKEQGLVGK-PSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAA 1718
            KKRKEQGLVGK P++   ++LQAGLRTLHDIGPEIRRAIS DL  +E       E     
Sbjct: 1620 KKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDE------PEETKRE 1673

Query: 1719 SEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG-SSQGDTESPSHEKLV 1777
             EDD+F+R G L GNHV++  SD R +  QT TT RPLH+ +       DTE P      
Sbjct: 1674 EEDDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAG 1733

Query: 1778 DST-FTPSSYSS------TGSNANINNANNTALGRLPRPA----GYPSTVSTVEGHGPPL 1826
            +S      +++S      T +NAN+NNAN +      RP+     + S       H    
Sbjct: 1734 NSVCHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHVSENGHHSSHKHDR 1793

Query: 1827 SPAIR--VQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLST 1884
             P  R  V+   +  +  R  S + Q     +E+      +      D     E    S+
Sbjct: 1794 EPQRRSSVKRTRYYETYIRSDSGDEQLPTICREDPEIHGYF-----RDPHCLGEQEYFSS 1848

Query: 1885 EMLSYQDD-----------------------------ENRQLTLPEEDK---RDIRQSPK 1912
            E   Y+DD                              + Q  L ++D     D R+SP+
Sbjct: 1849 EE-CYEDDSSPTWSRQNYGYYSRYPGRNIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPR 1907

Query: 1913 RGFL-RSASLGRRASFHLECLKRQKDR-----GGDISQKTVLPLHLVHHQALAVAGLSPL 1966
            R  L  + +  RR+SF+ ECL+RQ  +           +T LPLHL+  Q +AVAGL   
Sbjct: 1908 RRLLPPTPASHRRSSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSS 1967

Query: 1967 LQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAET 2026
              + +SP+   R +ATPPATP  R W P   P +++E  E+ +++N S PS+H  SW   
Sbjct: 1968 KAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTD 2027

Query: 2027 TPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEV 2086
             P      + R   P SL VPS           SA SLVEAVLISEGLG++A+DPKF+  
Sbjct: 2028 EP----DISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSA 2083

Query: 2087 TTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAG-QDRAGGEEDAGCV 2145
            T  E+ADACD+TI+EMESAA  +L+G      NG + P  + +D   QD   G  D    
Sbjct: 2084 TKHEIADACDLTIDEMESAASTLLNGNVRPRANGDVGPLSHRQDYELQDFGPGYSDEEPD 2143

Query: 2146 RARGRPSEEELQDSRVYVSSL 2166
              R    EE+L D  + +++L
Sbjct: 2144 PGR---DEEDLADEMICITTL 2161


>gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D
            subunit isoform a [Homo sapiens]
          Length = 2181

 Score = 2734 bits (7087), Expect = 0.0
 Identities = 1462/2201 (66%), Positives = 1667/2201 (75%), Gaps = 154/2201 (6%)

Query: 50   LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108
            LSWQAAIDAARQAK   +   +    V S +QRKRQQY K KKQG+++ +RP RAL CL+
Sbjct: 51   LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110

Query: 109  LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168
            L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI
Sbjct: 111  LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170

Query: 169  IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227
            IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK  +G N   GK
Sbjct: 171  IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230

Query: 228  GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287
              GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL
Sbjct: 231  SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290

Query: 288  ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346
            ELF+GKMHKTC+  +  +D+ AE+DP+PCA  +G+GRQC  NGT C+ GW GP  GITNF
Sbjct: 291  ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347

Query: 347  DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406
            DNFAFAMLTVFQCITMEGWTDVLYWVNDA+G +WPW+YFV+LII+GSFFVLNLVLGVLSG
Sbjct: 348  DNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSG 407

Query: 407  EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466
            EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM
Sbjct: 408  EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466

Query: 467  PTSETESVNTENVAGGDIEGEN---CGA-------------------RLAHRISKSKFSR 504
            PTSETESVNTENV+G   EGEN   CG+                   R    ISKSK SR
Sbjct: 467  PTSETESVNTENVSG---EGENRGCCGSLWCWWRRRGAAKAGPSGCRRWGQAISKSKLSR 523

Query: 505  YWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALL 564
             WRRWNRF RR+CRAAVKS  FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LL
Sbjct: 524  RWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLL 583

Query: 565  ALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRL 624
            ALFT EML+KMYSLGLQAYFVSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRL
Sbjct: 584  ALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRL 643

Query: 625  LRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQT 684
            LRIFK+TR+W SLSNLVASLLNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT
Sbjct: 644  LRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQT 703

Query: 685  RRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYIL 744
            +RSTFDNFPQ+LLTVFQILTGEDWN+VMYDGIMAYGGPS  GM+VCIYFIILFICGNYIL
Sbjct: 704  KRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYIL 763

Query: 745  LNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKI 804
            LNVFLAIAVDNLADAESL +AQKEE EEKERKK+AR  S E K+    KP V +      
Sbjct: 764  LNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD- 820

Query: 805  ELKSITADGESPPATKINMDDLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRP 859
                           K+ +DD +  E+EDK PYP       E   EE+E+EPE+P GPRP
Sbjct: 821  --------------NKVTIDDYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRP 865

Query: 860  RPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAA 919
            R +SEL++KEK  P+PE SAFFI S  N  R+ CH+++N  IFTNLIL FI+LSS +LAA
Sbjct: 866  RRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAA 925

Query: 920  EDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSV 979
            EDP++  SFRN IL YFD  FT IFT+EI LKMT +GAFLHKG+FCRNYFN+LD+LVV V
Sbjct: 926  EDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGV 985

Query: 980  SLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLL 1039
            SL+SFGIQSSAI+VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLL
Sbjct: 986  SLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLL 1045

Query: 1040 QFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFD 1099
            QFMFACIGVQLFKGK Y C+D +K    EC+G +I YKDG+VD P+++ R W+NS F+FD
Sbjct: 1046 QFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFD 1105

Query: 1100 NVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMN 1159
            NVL+AMMALFTVSTFEGWP LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMN
Sbjct: 1106 NVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMN 1165

Query: 1160 IFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNST 1219
            IFVGFVIVTFQEQGE+EYKNCELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+
Sbjct: 1166 IFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSS 1225

Query: 1220 YFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYF 1279
             FEY+MFVLI+LNT+CLAMQHY QS +F  AM+ILNM+FTG+FTVEM+LK+IAFKPKGYF
Sbjct: 1226 PFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYF 1285

Query: 1280 SDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQC 1339
            SD WN FD LIVIGSIIDV LSE +                        TE         
Sbjct: 1286 SDAWNTFDSLIVIGSIIDVALSEADP-----------------------TESENVPVPTA 1322

Query: 1340 SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLF 1399
            +P  N+EE++RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLI MLF
Sbjct: 1323 TPG-NSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLF 1381

Query: 1400 FIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKC 1459
            FIYAVIGMQ+FGK+A+ D  +INRNNNFQTFPQAVLLLFRCATGEAWQ+IMLAC+PGK C
Sbjct: 1382 FIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLC 1441

Query: 1460 APESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGP 1519
             PES+ +     E  CGS+FA+ YFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGP
Sbjct: 1442 DPESDYNPGE--EYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGP 1499

Query: 1520 HHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLN 1579
            HHLDEFKRIW+EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLV+MNMPLN
Sbjct: 1500 HHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLN 1559

Query: 1580 SDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDD 1639
            SDGTVMFNATLFALVRTAL+IKTEGNLEQANEELRA+IKKIWK+TSMKLLDQVVPPAGDD
Sbjct: 1560 SDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDD 1619

Query: 1640 EVTVGKFYATFLIQEYFRKFKKRKEQGLVGK-PSQRNALSLQAGLRTLHDIGPEIRRAIS 1698
            EVTVGKFYATFLIQ+YFRKFKKRKEQGLVGK P++   ++LQAGLRTLHDIGPEIRRAIS
Sbjct: 1620 EVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAIS 1679

Query: 1699 GDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHI 1758
             DL  +E       E      EDD+F+R G L GNHV++  SD R +  QT TT RPLH+
Sbjct: 1680 CDLQDDE------PEETKREEEDDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHV 1733

Query: 1759 NKAG-SSQGDTESPSHEKLVDST-FTPSSYSS------TGSNANINNANNTALGRLPRPA 1810
             +       DTE P      +S      +++S      T +NAN+NNAN +      RP+
Sbjct: 1734 QRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPS 1793

Query: 1811 ----GYPSTVSTVEGHGPPLSPAIR--VQEVAWKLSSNRCHSRESQAAMAGQEETSQDET 1864
                 + S       H     P  R  V+   +  +  R  S + Q     +E+      
Sbjct: 1794 IGNLEHVSENGHHSSHKHDREPQRRSSVKRTRYYETYIRSDSGDEQLPTICREDPEIHGY 1853

Query: 1865 YEVKMNHDTEACSEPSLLSTEMLSYQDD-----------------------------ENR 1895
            +      D     E    S+E   Y+DD                              + 
Sbjct: 1854 F-----RDPHCLGEQEYFSSEE-CYEDDSSPTWSRQNYGYYSRYPGRNIDSERPRGYHHP 1907

Query: 1896 QLTLPEEDK---RDIRQSPKRGFL-RSASLGRRASFHLECLKRQKDR-----GGDISQKT 1946
            Q  L ++D     D R+SP+R  L  + +  RR+SF+ ECL+RQ  +           +T
Sbjct: 1908 QGFLEDDDSPVCYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQSSQEEVPSSPIFPHRT 1967

Query: 1947 VLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVE 2006
             LPLHL+  Q +AVAGL     + +SP+   R +ATPPATP  R W P   P +++E  E
Sbjct: 1968 ALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQSE 2027

Query: 2007 SSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVE 2066
            + +++N S PS+H  SW    P      + R   P SL VPS           SA SLVE
Sbjct: 2028 ALDQVNGSLPSLHRSSWYTDEP----DISYRTFTPASLTVPSSFRNKNSDKQRSADSLVE 2083

Query: 2067 AVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFV 2126
            AVLISEGLG++A+DPKF+  T  E+ADACD+TI+EMESAA  +L+G      NG + P  
Sbjct: 2084 AVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLNGNVRPRANGDVGPLS 2143

Query: 2127 NCRDAG-QDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2166
            + +D   QD   G  D      R    EE+L D  + +++L
Sbjct: 2144 HRQDYELQDFGPGYSDEEPDPGR---DEEDLADEMICITTL 2181


>gi|192807298 calcium channel, voltage-dependent, L type, alpha 1D
            subunit isoform c [Homo sapiens]
          Length = 2137

 Score = 2734 bits (7086), Expect = 0.0
 Identities = 1454/2184 (66%), Positives = 1660/2184 (76%), Gaps = 164/2184 (7%)

Query: 50   LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108
            LSWQAAIDAARQAK   +   +    V S +QRKRQQY K KKQG+++ +RP RAL CL+
Sbjct: 51   LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110

Query: 109  LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168
            L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI
Sbjct: 111  LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170

Query: 169  IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227
            IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK  +G N   GK
Sbjct: 171  IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230

Query: 228  GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287
              GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL
Sbjct: 231  SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290

Query: 288  ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346
            ELF+GKMHKTC+  +  +D+ AE+DP+PCA  +G+GRQC  NGT C+ GW GP  GITNF
Sbjct: 291  ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347

Query: 347  DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406
            DNFAFAMLTVFQCITMEGWTDVLYW+NDA+G + PW+YFV+L+I GSFFVLNLVLGVLSG
Sbjct: 348  DNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSG 407

Query: 407  EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466
            EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM
Sbjct: 408  EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466

Query: 467  PTSETESVNTENVAGGDIEGEN--CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524
            PTSETESVNTENV+G   EGEN  C   L   ISKSK SR WRRWNRF RR+CRAAVKS 
Sbjct: 467  PTSETESVNTENVSG---EGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSV 523

Query: 525  VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584
             FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LLALFT EML+KMYSLGLQAYF
Sbjct: 524  TFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYF 583

Query: 585  VSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASL 644
            VSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRLLRIFK+TR+W SLSNLVASL
Sbjct: 584  VSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASL 643

Query: 645  LNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILT 704
            LNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT+RSTFDNFPQ+LLTVFQILT
Sbjct: 644  LNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILT 703

Query: 705  GEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764
            GEDWN+VMYDGIMAYGGPS  GM+VCIYFIILFICGNYILLNVFLAIAVDNLADAESL +
Sbjct: 704  GEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNT 763

Query: 765  AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMD 824
            AQKEE EEKERKK+AR  S E K+    KP V +                     K+ +D
Sbjct: 764  AQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD---------------NKVTID 806

Query: 825  DLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASA 879
            D +  E+EDK PYP       E   EE+E+EPE+P GPRPR +SEL++KEK  P+PE SA
Sbjct: 807  DYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSA 865

Query: 880  FFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIV 939
            FFI S  N  R+ CH+++N  IFTNLIL FI+LSS +LAAEDP++  SFRN IL YFD  
Sbjct: 866  FFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYA 925

Query: 940  FTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRV 999
            FT IFT+EI LKMT +GAFLHKG+FCRNYFN+LD+LVV VSL+SFGIQSSAI+VVKILRV
Sbjct: 926  FTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRV 985

Query: 1000 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS 1059
            LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Y C+
Sbjct: 986  LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCT 1045

Query: 1060 DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE 1119
            D +K    EC+G +I YKDG+VD P+++ R W+NS F+FDNVL+AMMALFTVSTFEGWP 
Sbjct: 1046 DEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPA 1105

Query: 1120 LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN 1179
            LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMNIFVGFVIVTFQEQGE+EYKN
Sbjct: 1106 LLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKN 1165

Query: 1180 CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239
            CELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ FEY+MFVLI+LNT+CLAMQ
Sbjct: 1166 CELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQ 1225

Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVI 1299
            HY QS +F  AM+ILNM+FTG+FTVEM+LK+IAFKPKGY                     
Sbjct: 1226 HYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGY--------------------- 1264

Query: 1300 LSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLF 1359
                   F DAWNTFD+LIV+GSI+D+A++E +           N+EE++RISITFFRLF
Sbjct: 1265 -------FSDAWNTFDSLIVIGSIIDVALSEAD-----------NSEESNRISITFFRLF 1306

Query: 1360 RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTT 1419
            RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLI MLFFIYAVIGMQ+FGK+A+ D  
Sbjct: 1307 RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNN 1366

Query: 1420 EINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSF 1479
            +INRNNNFQTFPQAVLLLFRCATGEAWQ+IMLAC+PGK C PES+ +   E    CGS+F
Sbjct: 1367 QINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGEE--YTCGSNF 1424

Query: 1480 AVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGR 1539
            A+ YFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDPEAKGR
Sbjct: 1425 AIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGR 1484

Query: 1540 IKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALR 1599
            IKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTVMFNATLFALVRTAL+
Sbjct: 1485 IKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALK 1544

Query: 1600 IKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKF 1659
            IKTEGNLEQANEELRA+IKKIWK+TSMKLLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKF
Sbjct: 1545 IKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKF 1604

Query: 1660 KKRKEQGLVGK-PSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAA 1718
            KKRKEQGLVGK P++   ++LQAGLRTLHDIGPEIRRAIS DL  +E       E     
Sbjct: 1605 KKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDE------PEETKRE 1658

Query: 1719 SEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG-SSQGDTESPSHEKLV 1777
             EDD+F+R G L GNHV++  SD R +  QT TT RPLH+ +       DTE P      
Sbjct: 1659 EEDDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAG 1718

Query: 1778 DST-FTPSSYSS------TGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAI 1830
            +S      +++S      T +NAN+NNAN +      RP+       +  GH        
Sbjct: 1719 NSVCHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHVSENGH-------- 1770

Query: 1831 RVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTE---------ACSEPSL 1881
                      S+  H RE Q   + +   S DE        D E            E   
Sbjct: 1771 ---------HSSHKHDREPQRRSSVKRSDSGDEQLPTICREDPEIHGYFRDPHCLGEQEY 1821

Query: 1882 LSTEMLSYQDD-----------------------------ENRQLTLPEEDK---RDIRQ 1909
             S+E   Y+DD                              + Q  L ++D     D R+
Sbjct: 1822 FSSEE-CYEDDSSPTWSRQNYGYYSRYPGRNIDSERPRGYHHPQGFLEDDDSPVCYDSRR 1880

Query: 1910 SPKRGFL-RSASLGRRASFHLECLKRQKDR-----GGDISQKTVLPLHLVHHQALAVAGL 1963
            SP+R  L  + +  RR+SF+ ECL+RQ  +           +T LPLHL+  Q +AVAGL
Sbjct: 1881 SPRRRLLPPTPASHRRSSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLMQQQIMAVAGL 1940

Query: 1964 SPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSW 2023
                 + +SP+   R +ATPPATP  R W P   P +++E  E+ +++N S PS+H  SW
Sbjct: 1941 DSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQSEALDQVNGSLPSLHRSSW 2000

Query: 2024 AETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKF 2083
                P      + R   P SL VPS           SA SLVEAVLISEGLG++A+DPKF
Sbjct: 2001 YTDEP----DISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKF 2056

Query: 2084 IEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAG-QDRAGGEEDA 2142
            +  T  E+ADACD+TI+EMESAA  +L+G      NG + P  + +D   QD   G  D 
Sbjct: 2057 VSATKHEIADACDLTIDEMESAASTLLNGNVRPRANGDVGPLSHRQDYELQDFGPGYSDE 2116

Query: 2143 GCVRARGRPSEEELQDSRVYVSSL 2166
                 R    EE+L D  + +++L
Sbjct: 2117 EPDPGR---DEEDLADEMICITTL 2137


>gi|110349767 calcium channel, voltage-dependent, L type, alpha 1S
            subunit [Homo sapiens]
          Length = 1873

 Score = 2299 bits (5957), Expect = 0.0
 Identities = 1180/1734 (68%), Positives = 1389/1734 (80%), Gaps = 72/1734 (4%)

Query: 77   SSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFA 136
            SS Q +  +  +PKK       RPPRAL CLTL+NP+R+ACISIVEWKPFE IILLTIFA
Sbjct: 4    SSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFA 63

Query: 137  NCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWN 196
            NCVALA+Y+P PEDD+N+ N  LE++EY FLI+F++EA +K+IAYG LFH +AYLR+GWN
Sbjct: 64   NCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWN 123

Query: 197  LLDFIIVVVGLFSAILEQATKADGANA-LGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQ 255
            +LDF IV +G+F+ ILEQ        A +  KGAG DVKALRAFRVLRPLRLVSGVPSLQ
Sbjct: 124  VLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQ 183

Query: 256  VVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGIADVPAEDDP 313
            VVLNSI KAM+PL HIALLVLF++IIYAIIGLELF GKMHKTCY    + +A V  E+ P
Sbjct: 184  VVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEE-P 242

Query: 314  SPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWV 372
            SPCA  TG GR+C  NG+ C+ GW GP HGIT+FDNF F+MLTV+QCITMEGWTDVLYWV
Sbjct: 243  SPCA-RTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWV 301

Query: 373  NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEE 432
            NDA+G +WPWIYFVTLI++GSFF+LNLVLGVLSGEF+KEREKAK+RG FQKLREKQQL+E
Sbjct: 302  NDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDE 361

Query: 433  DLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGAR 492
            DL+GY+ WITQ E +D E+  EG       ++    S+TES+        +I G N    
Sbjct: 362  DLRGYMSWITQGEVMDVEDFREGK-----LSLDEGGSDTESLY-------EIAGLN---- 405

Query: 493  LAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWL 552
                    +F R+WR+WNR  R KC   VKS VFYWLVI +V LNTL+IASEH+NQP WL
Sbjct: 406  -----KIIQFIRHWRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWL 460

Query: 553  TEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMS 612
            T +QD AN+ LL+LFT EML+KMY LGL+ YF+S+FNRFDCFVVC GILE +LVE+  M+
Sbjct: 461  TRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMT 520

Query: 613  PLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQL 672
            PLGISVLRC+RLLRIFKIT+YW SLSNLVASLLNS+RSIASLLLLLFLFI+IF+LLGMQL
Sbjct: 521  PLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQL 580

Query: 673  FGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIY 732
            FGG+++F++ + RRS FDNFPQ+L++VFQ+LTGEDW S+MY+GIMAYGGPS+PGMLVCIY
Sbjct: 581  FGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIY 640

Query: 733  FIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVE 792
            FIILF+CGNYILLNVFLAIAVDNLA+AESLTSAQK + EEK+R+K+++   P+K +E  E
Sbjct: 641  FIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEEKKRRKMSK-GLPDKSEE--E 697

Query: 793  KPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPE 852
            K  + +  E+K + + I      P   K+ +D+ + N NE K PYP+ +  G+++E+EPE
Sbjct: 698  KSTMAKKLEQKPKGEGI------PTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPE 751

Query: 853  MPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILL 912
            +P+ PRPRPL+EL LKEKAVP+PEAS+FFIFS  N+ R+ CHRIVN T FTN IL FILL
Sbjct: 752  IPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILL 811

Query: 913  SSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNIL 972
            SS +LAAEDP++  S RN IL +FDI FT++FT+EI LKMT YGAFLHKGSFCRNYFN+L
Sbjct: 812  SSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNML 871

Query: 973  DLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI 1032
            DLLVV+VSLIS G++SSAI+VVKILRVLRVLRPLRAINRAKGLKHVVQC+FVAI TIGNI
Sbjct: 872  DLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNI 931

Query: 1033 VIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWE 1092
            V+VTTLLQFMFACIGVQLFKGK + C+D SK TE EC+G Y  YKDG+     ++ R W 
Sbjct: 932  VLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWV 991

Query: 1093 NSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIII 1152
            +S F FDNVL+AMM+LFTVSTFEGWP+LLY++IDS+ ED GPIYN RVE++IFFIIYII+
Sbjct: 992  HSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIIL 1051

Query: 1153 IAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKV 1212
            IAFFMMNIFVGFVIVTFQEQGE EYKNCELDKNQRQCV+YALKARPLR YIPKN +QY+V
Sbjct: 1052 IAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQV 1111

Query: 1213 WYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIA 1272
            WY+V S+YFEYLMF LI+LNTICL MQHY QS       +ILN+ FT +FT+EMILKL+A
Sbjct: 1112 WYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMA 1171

Query: 1273 FKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVN 1332
            FK +GYF DPWNVFDFLIVIGSIIDVILSE + +   +      L  +G           
Sbjct: 1172 FKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASS----GGLYCLGG---------- 1217

Query: 1333 PAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVA 1392
                  C  +++ +E++RIS  FFRLFRVMRL+KLLSR EG+RTLLWTFIKSFQALPYVA
Sbjct: 1218 -----GCG-NVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVA 1271

Query: 1393 LLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLA 1452
            LLIVMLFFIYAVIGMQ+FGKIAL D T+INRNNNFQTFPQAVLLLFRCATGEAWQ+I+LA
Sbjct: 1272 LLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLA 1331

Query: 1453 CMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTR 1512
            C  GK C PES+ +     E  CG++FA +YFISFYMLCAFL+INLFVAVIMDNFDYLTR
Sbjct: 1332 CSYGKLCDPESDYAPGE--EYTCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTR 1389

Query: 1513 DWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLV 1572
            DWSILGPHHLDEFK IWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK CPHRVACKRLV
Sbjct: 1390 DWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLV 1449

Query: 1573 SMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQV 1632
             MNMPLNSDGTV FNATLFALVRTAL+IKTEGN EQANEELRAIIKKIWKRTSMKLLDQV
Sbjct: 1450 GMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQV 1509

Query: 1633 VPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTL-HDIGP 1691
            +PP GDDEVTVGKFYATFLIQE+FRKF KR+E+   G   +++ + +QAGLRT+  +  P
Sbjct: 1510 IPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEE-YYGYRPKKDIVQIQAGLRTIEEEAAP 1568

Query: 1692 EIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFT 1751
            EI R +SGDL AEEEL++AM   V AA E+ IFRR GGLFG   ++ +    ++ P    
Sbjct: 1569 EICRTVSGDLAAEEELERAM---VEAAMEEGIFRRTGGLFGQVDNFLER--TNSLPPVMA 1623

Query: 1752 TQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN-NTALG 1804
             QRPL    A     + ESP    +    F     ++  + AN NNAN N A G
Sbjct: 1624 NQRPLQF--AEIEMEEMESP----VFLEDFPQDPRTNPLARANTNNANANVAYG 1671



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 24/151 (15%)

Query: 1993 PPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGA 2052
            PP P    R+E     ++ +S+  S+H     E TP       +R  R  +    S+  A
Sbjct: 1737 PPAPCQCPRVESSMPEDRKSSTPGSLH-----EETPH------SRSTRENT----SRCSA 1781

Query: 2053 PGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSG 2112
            P      + + L++  L+  GLG  A D  FI  T Q LADAC M  EE+E  A  +L G
Sbjct: 1782 P------ATALLIQKALVRGGLGTLAADANFIMATGQALADACQMEPEEVEIMATELLKG 1835

Query: 2113 GAPQSPNGALLPFVNCRDAGQDRAGGEEDAG 2143
               ++P G +   + C + G      ++  G
Sbjct: 1836 --REAPEG-MASSLGCLNLGSSLGSLDQHQG 1863


>gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F
            subunit [Homo sapiens]
          Length = 1977

 Score = 2269 bits (5880), Expect = 0.0
 Identities = 1260/2176 (57%), Positives = 1493/2176 (68%), Gaps = 263/2176 (12%)

Query: 16   QGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATIST 75
            +G    +P P+ AN      AG  PE    PG           A + +  G++G      
Sbjct: 5    EGGKDTTPEPSPAN-----GAGPGPEWGLCPGPP---------AVEGESSGASG------ 44

Query: 76   VSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIF 135
               T ++R Q+ K K     +A R PRAL CLTL NP+RR+CISIVEWKPF+I+ILLTIF
Sbjct: 45   -LGTPKRRNQHSKHKTVAVASAQRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIF 103

Query: 136  ANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGW 195
            ANCVAL +YIPFPEDDSN  N NLE+VEY+FL+IFTVE  LK++AYGL+ HP+AY+RNGW
Sbjct: 104  ANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGW 163

Query: 196  NLLDFIIVVVGLFSAILEQATKADG-ANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSL 254
            NLLDFIIVVVGLFS +LEQ     G A   GGK  GFDVKALRAFRVLRPLRLVSGVPSL
Sbjct: 164  NLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSL 223

Query: 255  QVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPS 314
             +VLNSI+KA+VPLLHIALLVLFVIIIYAIIGLELF+G+MHKTCY     +D+ AE+DPS
Sbjct: 224  HIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLG--SDMEAEEDPS 281

Query: 315  PCALETGHGRQCQ-NGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373
            PCA  +G GR C  N T C+  W GP  GITNFDNF FAMLTVFQC+TMEGWTDVLYW+ 
Sbjct: 282  PCA-SSGSGRACTLNQTECRGRWPGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQ 340

Query: 374  DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433
            DA+G + PW+YFV+L+I GSFFVLNLVLGVLSGEFSKEREKAKARGDFQK REKQQ+EED
Sbjct: 341  DAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKQREKQQMEED 400

Query: 434  LKGYLDWITQAEDIDPEN----------EDEGMDEEKPR--------------------- 462
            L+GYLDWITQAE++D E+           +EG    +P+                     
Sbjct: 401  LRGYLDWITQAEELDMEDPSADDNLGSMAEEGRAGHRPQLAELTNRRRGRLRWFSHSTRS 460

Query: 463  ------NMSMPTSETESVNTENVAGGDIEG--ENCGARLAHRISKSKFSRYWRRWNRFCR 514
                  + S+P S+T S+        + EG   +C  R  ++I K++  R  RR NR  R
Sbjct: 461  THSTSSHASLPASDTGSMTETQGDEDEEEGALASC-TRCLNKIMKTRVCRRLRRANRVLR 519

Query: 515  RKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLK 574
             +CR AVKSN  YW V+ LVFLNTLTIASEH+ QP WLT++Q+ ANK LL LFT EMLLK
Sbjct: 520  ARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQIQEYANKVLLCLFTVEMLLK 579

Query: 575  MYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYW 634
            +Y LG  AY  S FNRFDCFVVCGGILET LVE   M PLGISVLRCVRLLRIFK+TR+W
Sbjct: 580  LYGLGPSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHW 639

Query: 635  NSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQ 694
             SLSNLVASLLNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFD+  T+RSTFD FPQ
Sbjct: 640  ASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQ 699

Query: 695  SLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVD 754
            +LLTVFQILTGEDWN VMYDGIMAYGGP FPGMLVCIYFIILFICGNYILLNVFLAIAVD
Sbjct: 700  ALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVD 759

Query: 755  NLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGE 814
            NLA  ++ T+  K  E+  E+        P++ + LV  P V + +EE    +       
Sbjct: 760  NLASGDAGTAKDKGGEKSNEKD------LPQENEGLV--PGVEKEEEEGARREGA----- 806

Query: 815  SPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPM 874
                      D++  E E+           EE+EEE E         L E+  KEK VP+
Sbjct: 807  ----------DMEEEEEEE-----------EEEEEEEEEEGAGGVELLQEVVPKEKVVPI 845

Query: 875  PEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILF 934
            PE SAFF  S  N  R  CH +++  +FTNLIL FI+LSS+SLAAEDP++  SFRNHIL 
Sbjct: 846  PEGSAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRNHILG 905

Query: 935  YFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVV 994
            YFD  FT+IFT+EI LKMT +GAFLH+GSFCR++FN+LDLLVVSVSLISFGI SSAI+VV
Sbjct: 906  YFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHSSAISVV 965

Query: 995  KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGK 1054
            KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK
Sbjct: 966  KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGK 1025

Query: 1055 LYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTF 1114
             YTC+D +K T  ECKG+++ Y DG+V  P+++ R W NS F+FDNVL+AMMALFTVSTF
Sbjct: 1026 FYTCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTF 1085

Query: 1115 EGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE 1174
            EGWP LLY++ID++ ED GPIYNYRVEIS+FFI+YIIIIAFFMMNIFVGFVI+TF+ QGE
Sbjct: 1086 EGWPALLYKAIDAYAEDHGPIYNYRVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGE 1145

Query: 1175 QEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTI 1234
            QEY+NCELDKNQRQCVEYALKA+PLRRYIPKN HQY+VW  VNS  FEYLMF+LILLNT+
Sbjct: 1146 QEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTV 1205

Query: 1235 CLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGS 1294
             LAMQHY Q+  F  AM+ILNM+FTGLFT+EM+LK+IAFKPK YF+D WN FD LIV+GS
Sbjct: 1206 ALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFTDAWNTFDALIVVGS 1265

Query: 1295 IIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISIT 1354
            I                            VDIA+TEVN   H       ++E++SRISIT
Sbjct: 1266 I----------------------------VDIAVTEVNNGGHL----GESSEDSSRISIT 1293

Query: 1355 FFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIA 1414
            FFRLFRVMRLVKLLS+GEGIRTLLWTFIKSFQALPYVALLI M+FFIYAVIGMQ+FGK+A
Sbjct: 1294 FFRLFRVMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVA 1353

Query: 1415 LNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETP 1474
            L D T+INRNNNFQTFPQAVLLLFRCATGEAWQ+IMLA +PG +C PES+       E  
Sbjct: 1354 LQDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDPESDFGPGE--EFT 1411

Query: 1475 CGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDP 1534
            CGS+FA+ YFISF+MLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDP
Sbjct: 1412 CGSNFAIAYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDP 1471

Query: 1535 EAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALV 1594
             AKGRIKHLDVV LLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTV FNATLFALV
Sbjct: 1472 GAKGRIKHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVTFNATLFALV 1531

Query: 1595 RTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQE 1654
            RT+L+IKTEGNLEQAN+ELR +IKKIWKR   KLLD+V+PP  ++EVTVGKFYATFLIQ+
Sbjct: 1532 RTSLKIKTEGNLEQANQELRIVIKKIWKRMKQKLLDEVIPPPDEEEVTVGKFYATFLIQD 1591

Query: 1655 YFRKFKKRKEQGLVGKPSQRNALS-LQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKE 1713
            YFRKF++RKE+GL+G  +  +  S LQAGLR+L D+GPE+R+A++ D   EEE     +E
Sbjct: 1592 YFRKFRRRKEKGLLGNDAAPSTSSALQAGLRSLQDLGPEMRQALTCDTEEEEE---EGQE 1648

Query: 1714 AVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTES--- 1770
             V    E D+                            T +   +++  + +G   S   
Sbjct: 1649 GVEEEDEKDL---------------------------ETNKATMVSQPSARRGSGISVSL 1681

Query: 1771 PSHEKLVDS-TFTPSS---YSSTGSNANINNANNTALGRLPRPAGYPSTVSTV--EGHGP 1824
            P  ++L DS +F PS     + T S  ++  A +    R     G  + + T+  EG+  
Sbjct: 1682 PVGDRLPDSLSFGPSDDDRGTPTSSQPSVPQAGSNTHRR-----GSGALIFTIPEEGNSQ 1736

Query: 1825 PLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLST 1884
            P                             GQ +  +DE    ++++  E    P     
Sbjct: 1737 P-------------------------KGTKGQNKQDEDEEVPDRLSYLDEQAGTPPC--- 1768

Query: 1885 EMLSYQDDENRQLTLPEEDKR--DIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDI 1942
                        L  P   +R  D    P+R  L     GR+ SF ++CL+RQ    G  
Sbjct: 1769 ----------SVLLPPHRAQRYMDGHLVPRRRLLPPTPAGRKPSFTIQCLQRQ----GSC 1814

Query: 1943 SQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRL 2002
                 LP+   +H+            R+  P      +ATPP     RG        L  
Sbjct: 1815 ED---LPIPGTYHRG-----------RNSGPNRAQGSWATPP----QRGRLLYAPLLLVE 1856

Query: 2003 EGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSAS 2062
            EG      L                   G SS   R     L VP     P     GSA 
Sbjct: 1857 EGAAGEGYL-------------------GRSSGPLRTF-TCLHVPGTHSDPSHGKRGSAD 1896

Query: 2063 SLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQ--SPNG 2120
            SLVEAVLISEGLG FA+DP+F+ +  QE+ADAC +T++EM++AA ++L+ G     S   
Sbjct: 1897 SLVEAVLISEGLGLFARDPRFVALAKQEIADACRLTLDEMDNAASDLLAQGTSSLYSDEE 1956

Query: 2121 ALLPFVNCRDAGQDRA 2136
            ++L   +  D G + A
Sbjct: 1957 SILSRFDEEDLGDEMA 1972


>gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo
            sapiens]
          Length = 2261

 Score =  761 bits (1966), Expect = 0.0
 Identities = 410/897 (45%), Positives = 566/897 (63%), Gaps = 84/897 (9%)

Query: 790  LVEKPAVGESKEEKIELKSITADGESPPATK--INMDDLQPNENEDKSPYPNPETTGEED 847
            +V  P+  ++   K   K      + PPA    +N   +Q N+N +  P P  E   +E+
Sbjct: 1146 IVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKEEEKKEE 1205

Query: 848  EEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLIL 907
            EE+     GP+P              MP  S+ FI S+ N  R  CH I+N   F   IL
Sbjct: 1206 EEDDRGEDGPKP--------------MPPYSSMFILSTTNPLRRLCHYILNLRYFEMCIL 1251

Query: 908  FFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRN 967
              I +SSI+LAAEDPVQ  + RN++L YFD VFT +FT E+ +KM   G  LH+G++ R+
Sbjct: 1252 MVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRD 1311

Query: 968  YFNILDLLVVSVSLISFGIQSSA----INVVKILRVLRVLRPLRAINRAKGLKHVVQCVF 1023
             +NILD +VVS +L++F    ++    IN +K LRVLRVLRPL+ I R   LK V  CV 
Sbjct: 1312 LWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVV 1371

Query: 1024 VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH 1083
             +++ + NI+IV  L  F+FA + VQLFKGK + C+D SK+ E +C+G Y+ Y+  EV  
Sbjct: 1372 NSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVK- 1430

Query: 1084 PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS 1143
               + R W+  +F +DNVL A++ LFTVST EGWP++L  S+D+  E++GP   YR+E+S
Sbjct: 1431 --ARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMS 1488

Query: 1144 IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI 1203
            IF+++Y ++  FF +NIFV  +I+TFQEQG++  +   L+KN+R C+++A+ A+PL R++
Sbjct: 1489 IFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHM 1548

Query: 1204 PKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGL 1261
            P+N+   QY++W  V S  FEY +  +I LNTI L M+ YG S  ++ A+ + N++FT L
Sbjct: 1549 PQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSL 1608

Query: 1262 FTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVG 1321
            F++E +LK++AF                         IL+    YF DAWN FD + V+G
Sbjct: 1609 FSLECVLKVMAFG------------------------ILN----YFRDAWNIFDFVTVLG 1640

Query: 1322 SIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTF 1381
            SI DI +TE                 N+ I+++F RLFR  RL+KLL +G  IR LLWTF
Sbjct: 1641 SITDILVTEFG---------------NNFINLSFLRLFRAARLIKLLRQGYTIRILLWTF 1685

Query: 1382 IKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALN--------DTTEINRNNNFQTFPQA 1433
            ++SF+ALPYV LLI MLFFIYA+IGMQVFG I ++        D  +I  +NNF+TF QA
Sbjct: 1686 VQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQA 1745

Query: 1434 VLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAF 1493
            ++LLFR ATGEAW +IML+C+ GK C       NS      CG+ FA FYF+SF  LC+F
Sbjct: 1746 LMLLFRSATGEAWHNIMLSCLSGKPC-----DKNSGILTRECGNEFAYFYFVSFIFLCSF 1800

Query: 1494 LIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQ 1553
            L++NLFVAVIMDNF+YLTRD SILGPHHLDE+ R+WAEYDP A GRI + D+ +LLR I 
Sbjct: 1801 LMLNLFVAVIMDNFEYLTRDSSILGPHHLDEYVRVWAEYDPAACGRIHYKDMYSLLRVIS 1860

Query: 1554 PPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE---GNLEQAN 1610
            PPLG GK CPHRVACKRL+ M++P+  D TV FN+TL AL+RTAL IK      + +Q +
Sbjct: 1861 PPLGLGKKCPHRVACKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKGGADKQQMD 1920

Query: 1611 EELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1667
             ELR  +  IW   S K LD +V P    ++TVGK YA  +I EY+R+ K +K Q +
Sbjct: 1921 AELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKAKKLQAM 1977



 Score =  671 bits (1730), Expect = 0.0
 Identities = 383/827 (46%), Positives = 507/827 (61%), Gaps = 64/827 (7%)

Query: 18  SNYGSPRPA-HANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTV 76
           + +G   PA +    + AAAG+        GA  S Q            G  G   +   
Sbjct: 2   ARFGDEMPARYGGGGSGAAAGVVVGSGGGRGAGGSRQG-----------GQPGAQRMYKQ 50

Query: 77  SSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLT 133
           S  QR R    Y   P +Q   T  R   +L   +  N +R+    I EW PFE +IL T
Sbjct: 51  SMAQRARTMALYNPIPVRQNCLTVNR---SLFLFSEDNVVRKYAKKITEWPPFEYMILAT 107

Query: 134 IFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN 193
           I ANC+ LA+    P+DD    +  L+  E  F+ IF  EA +K+IA G  FH  +YLRN
Sbjct: 108 IIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRN 167

Query: 194 GWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPS 253
           GWN++DF++V+ G+ + +                G  FD++ LRA RVLRPL+LVSG+PS
Sbjct: 168 GWNVMDFVVVLTGILATV----------------GTEFDLRTLRAVRVLRPLKLVSGIPS 211

Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313
           LQVVL SI+KAM+PLL I LL+ F I+I+AIIGLE +MGK H TC+ +EG  D+  E  P
Sbjct: 212 LQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCF-EEGTDDIQGES-P 269

Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373
           +PC  E    R C NGT C+P W+GP +GIT FDN  FA+LTVFQCITMEGWTD+LY  N
Sbjct: 270 APCGTEEP-ARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSN 328

Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433
           DA G  W W+YF+ LIIIGSFF+LNLVLGVLSGEF+KERE+ + R  F KLR +QQ+E +
Sbjct: 329 DASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERE 388

Query: 434 LKGYLDWITQAEDIDPENEDEGMDEEKP-----RNMSMPTSETESVNTENVAGGDIEGEN 488
           L GY++WI++AE++    ++   ++  P     R  ++  S+T+ +N E       +  +
Sbjct: 389 LNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIKKSKTDLLNPEEAEDQLADIAS 448

Query: 489 CG---ARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEH 545
            G   AR + + +K + S ++ +  R  R   R  VK+  FYW V+ LV LNTL +A  H
Sbjct: 449 VGSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVH 508

Query: 546 YNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETIL 605
           YNQP WL++    A    L LF +EM +KMY LG + YF S FN FDC V+ G I E I 
Sbjct: 509 YNQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIW 568

Query: 606 VETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIF 665
              K  +  GISVLR +RLLRIFK+T+YW SL NLV SLLNS++SI SLL LLFLFI++F
Sbjct: 569 AVIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVF 628

Query: 666 SLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP 725
           +LLGMQLFGG+FNFDE  T  + FD FP +++TVFQILTGEDWN VMYDGI + GG    
Sbjct: 629 ALLGMQLFGGQFNFDE-GTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQ-G 686

Query: 726 GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERK--------- 776
           GM+  IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT  ++EEEE   +K         
Sbjct: 687 GMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEV 746

Query: 777 ------KLARTASPEKKQELVEKPA--VGESKEEKIELKSITADGES 815
                   A  +   K+Q+  +KPA  V E +  ++  +++ A  E+
Sbjct: 747 AEVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREA 793



 Score =  202 bits (513), Expect = 4e-51
 Identities = 176/705 (24%), Positives = 317/705 (44%), Gaps = 120/705 (17%)

Query: 80   QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139
            + K+++    + +       P  ++  L+  NP+RR C  I+  + FE+ IL+ I  + +
Sbjct: 1200 EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI 1259

Query: 140  ALAIYIPFPEDDSNATNSNLERV-EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198
            ALA   P      NA  +N+ R  +Y+F  +FT E  +K+I  GL+ H  AY R+ WN+L
Sbjct: 1260 ALAAEDPV---QPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNIL 1316

Query: 199  DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258
            DFI+V   L +      +K    N          +K+LR  RVLRPL+ +  +P L+ V 
Sbjct: 1317 DFIVVSGALVAFAFTGNSKGKDINT---------IKSLRVLRVLRPLKTIKRLPKLKAVF 1367

Query: 259  NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK-MHKTCYNQEGIADVPAEDDPSPCA 317
            + ++ ++  + +I ++ +  + I+A++ ++LF GK  H T  ++E   D           
Sbjct: 1368 DCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDC---------- 1417

Query: 318  LETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV- 376
               G     +   V     +  K+   ++DN  +A+LT+F   T EGW  VL    DA  
Sbjct: 1418 --RGKYLLYEKNEVKARDREWKKYEF-HYDNVLWALLTLFTVSTGEGWPQVLKHSVDATF 1474

Query: 377  --------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQ 428
                     R    I++V   ++  FF +N+ + ++   F ++       GD  K+ E+ 
Sbjct: 1475 ENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KMMEEY 1525

Query: 429  QLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGEN 488
             LE++ +  +D+   A               KP    MP                     
Sbjct: 1526 SLEKNERACIDFAISA---------------KPLTRHMP--------------------- 1549

Query: 489  CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ 548
                      ++K S  +R W           V S  F + ++ ++ LNT+ +  + Y  
Sbjct: 1550 ----------QNKQSFQYRMWQ---------FVVSPPFEYTIMAMIALNTIVLMMKFYGA 1590

Query: 549  PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVET 608
                       N    +LF+ E +LK+ + G+  YF   +N FD   V G I + ILV  
Sbjct: 1591 SVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITD-ILVTE 1649

Query: 609  KIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLL 668
               + + +S LR  R  R+ K+ R   ++  L+ + + S +++  + LL+ +   I++++
Sbjct: 1650 FGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1709

Query: 669  GMQLFGG--------KFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAY 719
            GMQ+FG           + DE Q T  + F  F Q+L+ +F+  TGE W+++M   +   
Sbjct: 1710 GMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGK 1769

Query: 720  GGPSFPGML--------VCIYFI-ILFICGNYILLNVFLAIAVDN 755
                  G+L           YF+  +F+C ++++LN+F+A+ +DN
Sbjct: 1770 PCDKNSGILTRECGNEFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1813



 Score =  144 bits (362), Expect = 1e-33
 Identities = 179/785 (22%), Positives = 325/785 (41%), Gaps = 161/785 (20%)

Query: 480  AGGDIEGENCGARLAHRISKSKFSRYWRRWNRF-CRRKCRAAVKS-------NV------ 525
            AGG  +G   GA+  ++ S ++ +R    +N    R+ C    +S       NV      
Sbjct: 33   AGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAK 92

Query: 526  -------FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKM 575
                   F ++++  +  N + +A E +   +    ++E  D      + +F  E  +K+
Sbjct: 93   KITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKI 152

Query: 576  YSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT 631
             +LG      +Y  + +N  D  VV  GIL T+  E        +  LR VR+LR  K+ 
Sbjct: 153  IALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTE------FDLRTLRAVRVLRPLKLV 206

Query: 632  RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF-------DEMQT 684
                SL  ++ S++ ++  +  + LLLF  I+IF+++G++ + GKF+        D++Q 
Sbjct: 207  SGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQG 266

Query: 685  RR------------------------------STFDNFPQSLLTVFQILTGEDWNSVMYD 714
                                            + FDN   ++LTVFQ +T E W  ++Y+
Sbjct: 267  ESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYN 326

Query: 715  GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE 774
               A G          +YFI L I G++ +LN+ L +     A             +E+E
Sbjct: 327  SNDASGNT-----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERE 368

Query: 775  RKKLARTASPEKKQELVEKPAVGE----SKEEKIELKSITADGES--PPATKINMDDLQP 828
            R +  R     ++Q+ +E+   G     SK E++ L     DGE   P    +    ++ 
Sbjct: 369  RVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIK- 427

Query: 829  NENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNR 888
               + K+   NPE    ED+      VG    P +   +K   +   E S FF      R
Sbjct: 428  ---KSKTDLLNPEEA--EDQLADIASVGS---PFARASIKSAKL---ENSTFF-HKKERR 475

Query: 889  FRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEI 948
             R    R+V    F   +L  + L+++ +A     Q   + +  L+Y + +F  +F  E+
Sbjct: 476  MRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQ-PEWLSDFLYYAEFIFLGLFMSEM 534

Query: 949  ALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRP 1005
             +KM   G       +  + FN  D  V+  S+       I+      + +LR LR+LR 
Sbjct: 535  FIKMYGLGT----RPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRI 590

Query: 1006 LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT 1065
             +       L+++V  +  ++++I +++ +  L   +FA +G+QLF G+ +   + +  T
Sbjct: 591  FKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQ-FNFDEGTPPT 649

Query: 1066 EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI 1125
                                           +FD   AA+M +F + T E W E++Y  I
Sbjct: 650  -------------------------------NFDTFPAAIMTVFQILTGEDWNEVMYDGI 678

Query: 1126 DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEY 1177
             S    +G +       SI+FI+  +   + ++N+F+   +        +T  EQ E+E 
Sbjct: 679  KSQGGVQGGMV-----FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEA 733

Query: 1178 KNCEL 1182
             N +L
Sbjct: 734  ANQKL 738



 Score =  114 bits (285), Expect = 1e-24
 Identities = 96/331 (29%), Positives = 162/331 (48%), Gaps = 33/331 (9%)

Query: 879  AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936
            + F+FS +N  R    +I     F  +IL  I+ + I LA E   P    +  +  L   
Sbjct: 77   SLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDT 136

Query: 937  DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI-SFGIQSSAINVVK 995
            +  F  IF  E  +K+ A G   HKGS+ RN +N++D +VV   ++ + G +      ++
Sbjct: 137  EPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFD----LR 192

Query: 996  ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055
             LR +RVLRPL+ ++    L+ V++ +  A+  +  I ++      +FA IG++ + GK 
Sbjct: 193  TLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252

Query: 1056 YT------CSDSSKQTEAEC--KGNYITYKDGEVDHPIIQPRSWE---NSKFDFDNVLAA 1104
            +T        D   ++ A C  +    T  +G    P      WE   N    FDN+L A
Sbjct: 253  HTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPY-----WEGPNNGITQFDNILFA 307

Query: 1105 MMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 1164
            ++ +F   T EGW +LLY S D+     G  +N+     ++FI  III +FFM+N+ +G 
Sbjct: 308  VLTVFQCITMEGWTDLLYNSNDA----SGNTWNW-----LYFIPLIIIGSFFMLNLVLGV 358

Query: 1165 VIVTFQEQGEQ-EYKNCELDKNQRQCVEYAL 1194
            +   F ++ E+ E +   L   ++Q +E  L
Sbjct: 359  LSGEFAKERERVENRRAFLKLRRQQQIEREL 389



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 75/322 (23%), Positives = 138/322 (42%), Gaps = 70/322 (21%)

Query: 1195 KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL 1254
            K R +R YI +         +V +  F + +  L+ LNT+C+A+ HY Q       +   
Sbjct: 472  KERRMRFYIRR---------MVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYA 522

Query: 1255 NMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTF 1314
              +F GLF  EM +K+                                T  YF  ++N F
Sbjct: 523  EFIFLGLFMSEMFIKMYGLG----------------------------TRPYFHSSFNCF 554

Query: 1315 DALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGI 1374
            D  +++GSI ++    + P               +   I+  R  R++R+ K+      +
Sbjct: 555  DCGVIIGSIFEVIWAVIKPG--------------TSFGISVLRALRLLRIFKVTKYWASL 600

Query: 1375 RTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAV 1434
            R L+ + + S +++  +  L+ +   ++A++GMQ+FG     +  E     NF TFP A+
Sbjct: 601  RNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFG--GQFNFDEGTPPTNFDTFPAAI 658

Query: 1435 LLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFL 1494
            + +F+  TGE W ++M                  ++G    G  F++ YFI   +   + 
Sbjct: 659  MTVFQILTGEDWNEVMY-------------DGIKSQGGVQGGMVFSI-YFIVLTLFGNYT 704

Query: 1495 IINLFVAVIMDNF---DYLTRD 1513
            ++N+F+A+ +DN      LT+D
Sbjct: 705  LLNVFLAIAVDNLANAQELTKD 726



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 79/311 (25%), Positives = 143/311 (45%), Gaps = 41/311 (13%)

Query: 514  RRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNW-LTEVQDTANKALLALFTAEML 572
            RR C   +    F   ++ ++ ++++ +A+E   QPN     V    +     +FT EM+
Sbjct: 1234 RRLCHYILNLRYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMV 1293

Query: 573  LKMYSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLG-ISVLRCVRLLRI 627
            +KM  LGL     AYF  L+N  D  VV G ++            +  I  LR +R+LR 
Sbjct: 1294 IKMIDLGLVLHQGAYFRDLWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRP 1353

Query: 628  FKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF---------- 677
             K  +    L  +   ++NS++++ ++L++  LF+ IF+++ +QLF GKF          
Sbjct: 1354 LKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEF 1413

Query: 678  -----------NFDEMQTRRST-------FDNFPQSLLTVFQILTGEDWNSVM---YDGI 716
                         +E++ R          +DN   +LLT+F + TGE W  V+    D  
Sbjct: 1414 EKDCRGKYLLYEKNEVKARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDAT 1473

Query: 717  MAYGGPSFPG--MLVCIYFIILFICGNYILLNVFLAIAVDNLAD-AESLTSAQKEEEEEK 773
                GPS PG  M + I++++ F+   +  +N+F+A+ +    +  + +      E+ E+
Sbjct: 1474 FENQGPS-PGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNER 1532

Query: 774  ERKKLARTASP 784
                 A +A P
Sbjct: 1533 ACIDFAISAKP 1543



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 62/297 (20%)

Query: 125  PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184
            PFE  I+  I  N + L +        S A  + L     +F  +F++E  LKV+A+G+L
Sbjct: 1567 PFEYTIMAMIALNTIVLMMKF---YGASVAYENALRVFNIVFTSLFSLECVLKVMAFGIL 1623

Query: 185  FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244
                 Y R+ WN+ DF+ V+  +   ++ +     G N +       ++  LR FR  R 
Sbjct: 1624 ----NYFRDAWNIFDFVTVLGSITDILVTEF----GNNFI-------NLSFLRLFRAARL 1668

Query: 245  LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304
            ++L+    +++++L + +++   L ++ LL+  +  IYAIIG+++F            GI
Sbjct: 1669 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF---------GNIGI 1719

Query: 305  ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364
             DV  ED        T H                      NF  F  A++ +F+  T E 
Sbjct: 1720 -DVEDEDSDEDEFQITEH---------------------NNFRTFFQALMLLFRSATGEA 1757

Query: 365  WTDVLY-------------WVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408
            W +++               +    G ++ + YFV+ I + SF +LNL + V+   F
Sbjct: 1758 WHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1814



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 73/330 (22%), Positives = 121/330 (36%), Gaps = 109/330 (33%)

Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273
            FEY++   I+ N I LA++ +            ++     F G+F  E  +K+IA    F
Sbjct: 100  FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159

Query: 1274 KPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNP 1333
                Y  + WNV DF++V+  I                     L  VG+  D+       
Sbjct: 160  HKGSYLRNGWNVMDFVVVLTGI---------------------LATVGTEFDLRT----- 193

Query: 1334 AEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVAL 1393
                                   R  RV+R +KL+S    ++ +L + +K+   L  + L
Sbjct: 194  ----------------------LRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGL 231

Query: 1394 LIVMLFFIYAVIGMQVF-GKI-----------------ALNDTTEINR------------ 1423
            L+     I+A+IG++ + GK                  A   T E  R            
Sbjct: 232  LLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYW 291

Query: 1424 ---NNNFQTFPQ---AVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGS 1477
               NN    F     AVL +F+C T E W D++                NS +     G+
Sbjct: 292  EGPNNGITQFDNILFAVLTVFQCITMEGWTDLLY---------------NSNDAS---GN 333

Query: 1478 SFAVFYFISFYMLCAFLIINLFVAVIMDNF 1507
            ++   YFI   ++ +F ++NL + V+   F
Sbjct: 334  TWNWLYFIPLIIIGSFFMLNLVLGVLSGEF 363


>gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo
            sapiens]
          Length = 2506

 Score =  753 bits (1944), Expect = 0.0
 Identities = 406/897 (45%), Positives = 564/897 (62%), Gaps = 84/897 (9%)

Query: 790  LVEKPAVGESKEEKIELKSITADGESPPATK--INMDDLQPNENEDKSPYPNPETTGEED 847
            +V  P+  ++   K   K      + PPA    +N   +Q N+N +  P P  E   +E+
Sbjct: 1145 IVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKEEEKKEE 1204

Query: 848  EEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLIL 907
            EE+     GP+P              MP  S+ FI S+ N  R  CH I+N   F   IL
Sbjct: 1205 EEDDRGEDGPKP--------------MPPYSSMFILSTTNPLRRLCHYILNLRYFEMCIL 1250

Query: 908  FFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRN 967
              I +SSI+LAAEDPVQ  + RN++L YFD VFT +FT E+ +KM   G  LH+G++ R+
Sbjct: 1251 MVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRD 1310

Query: 968  YFNILDLLVVSVSLISFGIQSSA----INVVKILRVLRVLRPLRAINRAKGLKHVVQCVF 1023
             +NILD +VVS +L++F    ++    IN +K LRVLRVLRPL+ I R   LK V  CV 
Sbjct: 1311 LWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVV 1370

Query: 1024 VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH 1083
             +++ + NI+IV  L  F+FA + VQLFKGK + C+D SK+ E +C+G Y+ Y+  EV  
Sbjct: 1371 NSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVK- 1429

Query: 1084 PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS 1143
               + R W+  +F +DNVL A++ LFTVST EGWP++L  S+D+  E++GP   YR+E+S
Sbjct: 1430 --ARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMS 1487

Query: 1144 IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI 1203
            IF+++Y ++  FF +NIFV  +I+TFQEQG++  +   L+KN+R C+++A+ A+PL R++
Sbjct: 1488 IFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHM 1547

Query: 1204 PKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGL 1261
            P+N+   QY++W  V S  FEY +  +I LNTI L M+ YG S  ++ A+ + N++FT L
Sbjct: 1548 PQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSL 1607

Query: 1262 FTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVG 1321
            F++E +LK++AF                         IL+    YF DAWN FD + V+G
Sbjct: 1608 FSLECVLKVMAFG------------------------ILN----YFRDAWNIFDFVTVLG 1639

Query: 1322 SIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTF 1381
            SI DI +TE                 N+ I+++F RLFR  RL+KLL +G  IR LLWTF
Sbjct: 1640 SITDILVTEFG---------------NNFINLSFLRLFRAARLIKLLRQGYTIRILLWTF 1684

Query: 1382 IKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALN--------DTTEINRNNNFQTFPQA 1433
            ++SF+ALPYV LLI MLFFIYA+IGMQVFG I ++        D  +I  +NNF+TF QA
Sbjct: 1685 VQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQA 1744

Query: 1434 VLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAF 1493
            ++LLFR ATGEAW +IML+C+ GK C       NS      CG+ FA FYF+SF  LC+F
Sbjct: 1745 LMLLFRSATGEAWHNIMLSCLSGKPC-----DKNSGILTRECGNEFAYFYFVSFIFLCSF 1799

Query: 1494 LIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQ 1553
            L++NLFVAVIMDNF+YLTRD SILGPHHLDE+ R+WAEYDP A GR+ +LD+  +LR + 
Sbjct: 1800 LMLNLFVAVIMDNFEYLTRDSSILGPHHLDEYVRVWAEYDPAAWGRMPYLDMYQMLRHMS 1859

Query: 1554 PPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE---GNLEQAN 1610
            PPLG GK CP RVA KRL+ M++P+  D TV FN+TL AL+RTAL IK      + +Q +
Sbjct: 1860 PPLGLGKKCPARVAYKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKGGADKQQMD 1919

Query: 1611 EELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1667
             ELR  +  IW   S K LD +V P    ++TVGK YA  +I EY+R+ K +K Q +
Sbjct: 1920 AELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSKAKKLQAM 1976



 Score =  671 bits (1731), Expect = 0.0
 Identities = 383/826 (46%), Positives = 507/826 (61%), Gaps = 63/826 (7%)

Query: 18  SNYGSPRPA-HANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTV 76
           + +G   PA +    + AAAG+        GA  S Q            G  G   +   
Sbjct: 2   ARFGDEMPARYGGGGSGAAAGVVVGSGGGRGAGGSRQG-----------GQPGAQRMYKQ 50

Query: 77  SSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLT 133
           S  QR R    Y   P +Q   T  R   +L   +  N +R+    I EW PFE +IL T
Sbjct: 51  SMAQRARTMALYNPIPVRQNCLTVNR---SLFLFSEDNVVRKYAKKITEWPPFEYMILAT 107

Query: 134 IFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN 193
           I ANC+ LA+    P+DD    +  L+  E  F+ IF  EA +K+IA G  FH  +YLRN
Sbjct: 108 IIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRN 167

Query: 194 GWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPS 253
           GWN++DF++V+ G+ + +                G  FD++ LRA RVLRPL+LVSG+PS
Sbjct: 168 GWNVMDFVVVLTGILATV----------------GTEFDLRTLRAVRVLRPLKLVSGIPS 211

Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313
           LQVVL SI+KAM+PLL I LL+ F I+I+AIIGLE +MGK H TC+ +EG  D+  E  P
Sbjct: 212 LQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCF-EEGTDDIQGES-P 269

Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373
           +PC  E    R C NGT C+P W+GP +GIT FDN  FA+LTVFQCITMEGWTD+LY  N
Sbjct: 270 APCGTEEP-ARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSN 328

Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433
           DA G  W W+YF+ LIIIGSFF+LNLVLGVLSGEF+KERE+ + R  F KLR +QQ+E +
Sbjct: 329 DASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERE 388

Query: 434 LKGYLDWITQAEDIDPENEDEGMDEEKP----RNMSMPTSETESVNTENVAGGDIEGENC 489
           L GY++WI++AE++    ++   ++  P    R  ++  S+T+ +N E       +  + 
Sbjct: 389 LNGYMEWISKAEEVILAEDETDGEQRHPFDALRRTTIKKSKTDLLNPEEAEDQLADIASV 448

Query: 490 G---ARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHY 546
           G   AR + + +K + S ++ +  R  R   R  VK+  FYW V+ LV LNTL +A  HY
Sbjct: 449 GSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHY 508

Query: 547 NQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILV 606
           NQP WL++    A    L LF +EM +KMY LG + YF S FN FDC V+ G I E I  
Sbjct: 509 NQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWA 568

Query: 607 ETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFS 666
             K  +  GISVLR +RLLRIFK+T+YW SL NLV SLLNS++SI SLL LLFLFI++F+
Sbjct: 569 VIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFA 628

Query: 667 LLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPG 726
           LLGMQLFGG+FNFDE  T  + FD FP +++TVFQILTGEDWN VMYDGI + GG    G
Sbjct: 629 LLGMQLFGGQFNFDE-GTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQ-GG 686

Query: 727 MLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERK---------- 776
           M+  IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT  ++EEEE   +K          
Sbjct: 687 MVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEVA 746

Query: 777 -----KLARTASPEKKQELVEKPA--VGESKEEKIELKSITADGES 815
                  A  +   K+Q+  +KPA  V E +  ++  +++ A  E+
Sbjct: 747 EVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREA 792



 Score =  202 bits (513), Expect = 4e-51
 Identities = 176/705 (24%), Positives = 317/705 (44%), Gaps = 120/705 (17%)

Query: 80   QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139
            + K+++    + +       P  ++  L+  NP+RR C  I+  + FE+ IL+ I  + +
Sbjct: 1199 EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI 1258

Query: 140  ALAIYIPFPEDDSNATNSNLERV-EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198
            ALA   P      NA  +N+ R  +Y+F  +FT E  +K+I  GL+ H  AY R+ WN+L
Sbjct: 1259 ALAAEDPV---QPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNIL 1315

Query: 199  DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258
            DFI+V   L +      +K    N          +K+LR  RVLRPL+ +  +P L+ V 
Sbjct: 1316 DFIVVSGALVAFAFTGNSKGKDINT---------IKSLRVLRVLRPLKTIKRLPKLKAVF 1366

Query: 259  NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK-MHKTCYNQEGIADVPAEDDPSPCA 317
            + ++ ++  + +I ++ +  + I+A++ ++LF GK  H T  ++E   D           
Sbjct: 1367 DCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDC---------- 1416

Query: 318  LETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV- 376
               G     +   V     +  K+   ++DN  +A+LT+F   T EGW  VL    DA  
Sbjct: 1417 --RGKYLLYEKNEVKARDREWKKYEF-HYDNVLWALLTLFTVSTGEGWPQVLKHSVDATF 1473

Query: 377  --------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQ 428
                     R    I++V   ++  FF +N+ + ++   F ++       GD  K+ E+ 
Sbjct: 1474 ENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KMMEEY 1524

Query: 429  QLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGEN 488
             LE++ +  +D+   A               KP    MP                     
Sbjct: 1525 SLEKNERACIDFAISA---------------KPLTRHMP--------------------- 1548

Query: 489  CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ 548
                      ++K S  +R W           V S  F + ++ ++ LNT+ +  + Y  
Sbjct: 1549 ----------QNKQSFQYRMWQ---------FVVSPPFEYTIMAMIALNTIVLMMKFYGA 1589

Query: 549  PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVET 608
                       N    +LF+ E +LK+ + G+  YF   +N FD   V G I + ILV  
Sbjct: 1590 SVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITD-ILVTE 1648

Query: 609  KIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLL 668
               + + +S LR  R  R+ K+ R   ++  L+ + + S +++  + LL+ +   I++++
Sbjct: 1649 FGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1708

Query: 669  GMQLFGG--------KFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAY 719
            GMQ+FG           + DE Q T  + F  F Q+L+ +F+  TGE W+++M   +   
Sbjct: 1709 GMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGK 1768

Query: 720  GGPSFPGML--------VCIYFI-ILFICGNYILLNVFLAIAVDN 755
                  G+L           YF+  +F+C ++++LN+F+A+ +DN
Sbjct: 1769 PCDKNSGILTRECGNEFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1812



 Score =  145 bits (366), Expect = 4e-34
 Identities = 179/784 (22%), Positives = 325/784 (41%), Gaps = 160/784 (20%)

Query: 480  AGGDIEGENCGARLAHRISKSKFSRYWRRWNRF-CRRKCRAAVKS-------NV------ 525
            AGG  +G   GA+  ++ S ++ +R    +N    R+ C    +S       NV      
Sbjct: 33   AGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAK 92

Query: 526  -------FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKM 575
                   F ++++  +  N + +A E +   +    ++E  D      + +F  E  +K+
Sbjct: 93   KITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKI 152

Query: 576  YSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT 631
             +LG      +Y  + +N  D  VV  GIL T+  E        +  LR VR+LR  K+ 
Sbjct: 153  IALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTE------FDLRTLRAVRVLRPLKLV 206

Query: 632  RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF-------DEMQT 684
                SL  ++ S++ ++  +  + LLLF  I+IF+++G++ + GKF+        D++Q 
Sbjct: 207  SGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQG 266

Query: 685  RR------------------------------STFDNFPQSLLTVFQILTGEDWNSVMYD 714
                                            + FDN   ++LTVFQ +T E W  ++Y+
Sbjct: 267  ESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYN 326

Query: 715  GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE 774
               A G          +YFI L I G++ +LN+ L +     A             +E+E
Sbjct: 327  SNDASGNT-----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERE 368

Query: 775  RKKLARTASPEKKQELVEKPAVGE----SKEEKIELKSITADGESP-PATKINMDDLQPN 829
            R +  R     ++Q+ +E+   G     SK E++ L     DGE   P   +    ++  
Sbjct: 369  RVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDALRRTTIK-- 426

Query: 830  ENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRF 889
              + K+   NPE    ED+      VG    P +   +K   +   E S FF      R 
Sbjct: 427  --KSKTDLLNPEEA--EDQLADIASVGS---PFARASIKSAKL---ENSTFF-HKKERRM 475

Query: 890  RLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA 949
            R    R+V    F   +L  + L+++ +A     Q   + +  L+Y + +F  +F  E+ 
Sbjct: 476  RFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQ-PEWLSDFLYYAEFIFLGLFMSEMF 534

Query: 950  LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRPL 1006
            +KM   G       +  + FN  D  V+  S+       I+      + +LR LR+LR  
Sbjct: 535  IKMYGLGT----RPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIF 590

Query: 1007 RAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTE 1066
            +       L+++V  +  ++++I +++ +  L   +FA +G+QLF G+ +   + +  T 
Sbjct: 591  KVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQ-FNFDEGTPPT- 648

Query: 1067 AECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSID 1126
                                          +FD   AA+M +F + T E W E++Y  I 
Sbjct: 649  ------------------------------NFDTFPAAIMTVFQILTGEDWNEVMYDGIK 678

Query: 1127 SHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEYK 1178
            S    +G +       SI+FI+  +   + ++N+F+   +        +T  EQ E+E  
Sbjct: 679  SQGGVQGGMV-----FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAA 733

Query: 1179 NCEL 1182
            N +L
Sbjct: 734  NQKL 737



 Score =  114 bits (285), Expect = 1e-24
 Identities = 96/331 (29%), Positives = 162/331 (48%), Gaps = 33/331 (9%)

Query: 879  AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936
            + F+FS +N  R    +I     F  +IL  I+ + I LA E   P    +  +  L   
Sbjct: 77   SLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDT 136

Query: 937  DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI-SFGIQSSAINVVK 995
            +  F  IF  E  +K+ A G   HKGS+ RN +N++D +VV   ++ + G +      ++
Sbjct: 137  EPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFD----LR 192

Query: 996  ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055
             LR +RVLRPL+ ++    L+ V++ +  A+  +  I ++      +FA IG++ + GK 
Sbjct: 193  TLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252

Query: 1056 YT------CSDSSKQTEAEC--KGNYITYKDGEVDHPIIQPRSWE---NSKFDFDNVLAA 1104
            +T        D   ++ A C  +    T  +G    P      WE   N    FDN+L A
Sbjct: 253  HTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPY-----WEGPNNGITQFDNILFA 307

Query: 1105 MMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 1164
            ++ +F   T EGW +LLY S D+     G  +N+     ++FI  III +FFM+N+ +G 
Sbjct: 308  VLTVFQCITMEGWTDLLYNSNDA----SGNTWNW-----LYFIPLIIIGSFFMLNLVLGV 358

Query: 1165 VIVTFQEQGEQ-EYKNCELDKNQRQCVEYAL 1194
            +   F ++ E+ E +   L   ++Q +E  L
Sbjct: 359  LSGEFAKERERVENRRAFLKLRRQQQIEREL 389



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 75/322 (23%), Positives = 138/322 (42%), Gaps = 70/322 (21%)

Query: 1195 KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL 1254
            K R +R YI +         +V +  F + +  L+ LNT+C+A+ HY Q       +   
Sbjct: 471  KERRMRFYIRR---------MVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYA 521

Query: 1255 NMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTF 1314
              +F GLF  EM +K+                                T  YF  ++N F
Sbjct: 522  EFIFLGLFMSEMFIKMYGLG----------------------------TRPYFHSSFNCF 553

Query: 1315 DALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGI 1374
            D  +++GSI ++    + P               +   I+  R  R++R+ K+      +
Sbjct: 554  DCGVIIGSIFEVIWAVIKPG--------------TSFGISVLRALRLLRIFKVTKYWASL 599

Query: 1375 RTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAV 1434
            R L+ + + S +++  +  L+ +   ++A++GMQ+FG     +  E     NF TFP A+
Sbjct: 600  RNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFG--GQFNFDEGTPPTNFDTFPAAI 657

Query: 1435 LLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFL 1494
            + +F+  TGE W ++M                  ++G    G  F++ YFI   +   + 
Sbjct: 658  MTVFQILTGEDWNEVMY-------------DGIKSQGGVQGGMVFSI-YFIVLTLFGNYT 703

Query: 1495 IINLFVAVIMDNF---DYLTRD 1513
            ++N+F+A+ +DN      LT+D
Sbjct: 704  LLNVFLAIAVDNLANAQELTKD 725



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 79/311 (25%), Positives = 143/311 (45%), Gaps = 41/311 (13%)

Query: 514  RRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNW-LTEVQDTANKALLALFTAEML 572
            RR C   +    F   ++ ++ ++++ +A+E   QPN     V    +     +FT EM+
Sbjct: 1233 RRLCHYILNLRYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMV 1292

Query: 573  LKMYSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLG-ISVLRCVRLLRI 627
            +KM  LGL     AYF  L+N  D  VV G ++            +  I  LR +R+LR 
Sbjct: 1293 IKMIDLGLVLHQGAYFRDLWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRP 1352

Query: 628  FKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF---------- 677
             K  +    L  +   ++NS++++ ++L++  LF+ IF+++ +QLF GKF          
Sbjct: 1353 LKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEF 1412

Query: 678  -----------NFDEMQTRRST-------FDNFPQSLLTVFQILTGEDWNSVM---YDGI 716
                         +E++ R          +DN   +LLT+F + TGE W  V+    D  
Sbjct: 1413 EKDCRGKYLLYEKNEVKARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDAT 1472

Query: 717  MAYGGPSFPG--MLVCIYFIILFICGNYILLNVFLAIAVDNLAD-AESLTSAQKEEEEEK 773
                GPS PG  M + I++++ F+   +  +N+F+A+ +    +  + +      E+ E+
Sbjct: 1473 FENQGPS-PGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNER 1531

Query: 774  ERKKLARTASP 784
                 A +A P
Sbjct: 1532 ACIDFAISAKP 1542



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 62/297 (20%)

Query: 125  PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184
            PFE  I+  I  N + L +        S A  + L     +F  +F++E  LKV+A+G+L
Sbjct: 1566 PFEYTIMAMIALNTIVLMMKF---YGASVAYENALRVFNIVFTSLFSLECVLKVMAFGIL 1622

Query: 185  FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244
                 Y R+ WN+ DF+ V+  +   ++ +     G N +       ++  LR FR  R 
Sbjct: 1623 ----NYFRDAWNIFDFVTVLGSITDILVTEF----GNNFI-------NLSFLRLFRAARL 1667

Query: 245  LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304
            ++L+    +++++L + +++   L ++ LL+  +  IYAIIG+++F            GI
Sbjct: 1668 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF---------GNIGI 1718

Query: 305  ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364
             DV  ED        T H                      NF  F  A++ +F+  T E 
Sbjct: 1719 -DVEDEDSDEDEFQITEH---------------------NNFRTFFQALMLLFRSATGEA 1756

Query: 365  WTDVLY-------------WVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408
            W +++               +    G ++ + YFV+ I + SF +LNL + V+   F
Sbjct: 1757 WHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1813



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 73/330 (22%), Positives = 121/330 (36%), Gaps = 109/330 (33%)

Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273
            FEY++   I+ N I LA++ +            ++     F G+F  E  +K+IA    F
Sbjct: 100  FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159

Query: 1274 KPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNP 1333
                Y  + WNV DF++V+  I                     L  VG+  D+       
Sbjct: 160  HKGSYLRNGWNVMDFVVVLTGI---------------------LATVGTEFDLRT----- 193

Query: 1334 AEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVAL 1393
                                   R  RV+R +KL+S    ++ +L + +K+   L  + L
Sbjct: 194  ----------------------LRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGL 231

Query: 1394 LIVMLFFIYAVIGMQVF-GKI-----------------ALNDTTEINR------------ 1423
            L+     I+A+IG++ + GK                  A   T E  R            
Sbjct: 232  LLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYW 291

Query: 1424 ---NNNFQTFPQ---AVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGS 1477
               NN    F     AVL +F+C T E W D++                NS +     G+
Sbjct: 292  EGPNNGITQFDNILFAVLTVFQCITMEGWTDLLY---------------NSNDAS---GN 333

Query: 1478 SFAVFYFISFYMLCAFLIINLFVAVIMDNF 1507
            ++   YFI   ++ +F ++NL + V+   F
Sbjct: 334  TWNWLYFIPLIIIGSFFMLNLVLGVLSGEF 363


>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
            subunit [Homo sapiens]
          Length = 2339

 Score =  753 bits (1944), Expect = 0.0
 Identities = 430/975 (44%), Positives = 588/975 (60%), Gaps = 102/975 (10%)

Query: 764  SAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESP----PAT 819
            + +KE  E++  +K A     +K++EL       + +E   +L++       P    P+T
Sbjct: 991  AVEKETTEKEATEKEAEIVEADKEKELRNH----QPREPHCDLETSGTVTVGPMHTLPST 1046

Query: 820  KINMDDLQPNENEDK-------SPYPNPETTGEEDEEEPEMPVGPRPR----PLSELHLK 868
             +   + QP + +++       S  P+P T        P M  GP       P   + L+
Sbjct: 1047 CLQKVEEQPEDADNQRNVTRMGSQPPDPNTI----VHIPVMLTGPLGEATVVPSGNVDLE 1102

Query: 869  EKAV----------------PMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILL 912
             +A                 P+   S+ F  S  N  R  CH IV    F  +IL  I L
Sbjct: 1103 SQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFCHYIVTMRYFEVVILVVIAL 1162

Query: 913  SSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNIL 972
            SSI+LAAEDPV+  S RN+ L Y D +FT +FT E+ +KM   G  LH G++ R+ +NIL
Sbjct: 1163 SSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNIL 1222

Query: 973  DLLVVSVSLISFGIQSSA---INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTI 1029
            D +VVS +L++F    S    IN +K LRVLRVLRPL+ I R   LK V  CV  +++ +
Sbjct: 1223 DFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNV 1282

Query: 1030 GNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPR 1089
             NI+IV  L  F+FA I VQLFKGK + C+D SK+ E +C+G Y+ Y+  EV+    QPR
Sbjct: 1283 LNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELERDCRGQYLDYEKEEVE---AQPR 1339

Query: 1090 SWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIY 1149
             W+   F +DNVL A++ LFTVST EGWP +L  S+D+  E++GP   YR+E+SIF+++Y
Sbjct: 1340 QWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVY 1399

Query: 1150 IIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH- 1208
             ++  FF +NIFV  +I+TFQEQG++    C L+KN+R C+++A+ A+PL RY+P+N+  
Sbjct: 1400 FVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFAISAKPLTRYMPQNRQS 1459

Query: 1209 -QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMI 1267
             QYK W  V S  FEY +  +I LNT+ L M+ Y     +++ +  LN++FT +F++E +
Sbjct: 1460 FQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECV 1519

Query: 1268 LKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIA 1327
            LK+IAF    YF D                            AWN FD + V+GSI DI 
Sbjct: 1520 LKIIAFGVLNYFRD----------------------------AWNVFDFVTVLGSITDIL 1551

Query: 1328 ITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQA 1387
            +TE+             AE N+ I+++F RLFR  RL+KLL +G  IR LLWTF++SF+A
Sbjct: 1552 VTEI-------------AETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKA 1598

Query: 1388 LPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQ 1447
            LPYV LLI MLFFIYA+IGMQVFG IAL+D T INR+NNF+TF QA++LLFR ATGEAW 
Sbjct: 1599 LPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWH 1658

Query: 1448 DIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF 1507
            +IML+C+  + C    E +N+TE    CGS FA FYF+SF  LC+FL++NLFVAVIMDNF
Sbjct: 1659 EIMLSCLSNQAC---DEQANATE----CGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1711

Query: 1508 DYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVA 1567
            +YLTRD SILGPHHLDEF R+WAEYDP A GRI + D+  +L+ + PPLG GK CP RVA
Sbjct: 1712 EYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVA 1771

Query: 1568 CKRLVSMNMPL-NSDGTVMFNATLFALVRTALRIK---TEGNLEQANEELRAIIKKIWKR 1623
             KRLV MNMP+ N D TV F +TL AL+RTAL IK         Q + ELR  I  +W  
Sbjct: 1772 YKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWAN 1831

Query: 1624 TSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKE--QGLVGKPSQRNALSLQA 1681
               K LD +VPP   DE+TVGK YA  +I +++++ K  ++  Q   G  SQ   +SL  
Sbjct: 1832 LPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFH 1891

Query: 1682 GLR-TLHDIGPEIRR 1695
             L+ TL    P + R
Sbjct: 1892 PLKATLEQTQPAVLR 1906



 Score =  648 bits (1671), Expect = 0.0
 Identities = 371/803 (46%), Positives = 486/803 (60%), Gaps = 59/803 (7%)

Query: 89  PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFP 148
           P KQ   T  R   +L   +  N +R+    I EW PFE +IL TI ANC+ LA+    P
Sbjct: 63  PVKQNCFTVNR---SLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLP 119

Query: 149 EDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLF 208
           + D    +  L+  E  F+ IF  EA +K+IA G +FH  +YLRNGWN++DF++V+ G+ 
Sbjct: 120 DGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGI- 178

Query: 209 SAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPL 268
                          L   G  FD++ LRA RVLRPL+LVSG+PSLQVVL SI+KAMVPL
Sbjct: 179 ---------------LATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPL 223

Query: 269 LHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQN 328
           L I LL+ F I+++AIIGLE +MGK HK C+     A+ P  D   PC  E    R C+ 
Sbjct: 224 LQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAE-PVGD--FPCGKEAP-ARLCEG 279

Query: 329 GTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTL 388
            T C+  W GP  GITNFDN  FA+LTVFQCITMEGWTD+LY  NDA G  W W+YF+ L
Sbjct: 280 DTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPL 339

Query: 389 IIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDID 448
           IIIGSFF+LNLVLGVLSGEF+KERE+ + R  F KLR +QQ+E +L GYL+WI +AE++ 
Sbjct: 340 IIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVM 399

Query: 449 PENEDEGMDEEKP----RNMSMPTSETESVNTENVAGGDIEGENCG-----ARLAHRISK 499
              ED   +E+ P    +  +   S  + ++ E   G D   + C      AR + +  K
Sbjct: 400 LAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAEE--GEDRFADLCAVGSPFARASLKSGK 457

Query: 500 SKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTA 559
           ++ S Y+RR  +  R   R  VK+  FYW+V+ +V LNTL +A  HYNQP  LT     A
Sbjct: 458 TESSSYFRRKEKMFRFFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFA 517

Query: 560 NKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVL 619
               L LF  EM LKMY LG ++YF S FN FD  V+ G + E +    K  S  GISVL
Sbjct: 518 EFVFLGLFLTEMSLKMYGLGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVL 577

Query: 620 RCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF 679
           R +RLLRIFK+T+YW+SL NLV SLLNS++SI SLL LLFLFI++F+LLGMQLFGG+FNF
Sbjct: 578 RALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNF 637

Query: 680 DEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFIC 739
            + +T  + FD FP ++LTVFQILTGEDWN+VMY GI + GG S  GM    YFI+L + 
Sbjct: 638 QD-ETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIESQGGVS-KGMFSSFYFIVLTLF 695

Query: 740 GNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE-------------- 785
           GNY LLNVFLAIAVDNLA+A+ LT   +EE EE   +KLA   + E              
Sbjct: 696 GNYTLLNVFLAIAVDNLANAQELTK-DEEEMEEAANQKLALQKAKEVAEVSPMSAANISI 754

Query: 786 --KKQELVEKPAVGESKEEKIELKSITAD-----GESPPATKINMDDLQPNENEDKSPYP 838
             ++Q   +  +V E +  ++ L+++ A       E  P  ++     +    + K+   
Sbjct: 755 AARQQNSAKARSVWEQRASQLRLQNLRASCEALYSEMDPEERLRFATTRHLRPDMKTHLD 814

Query: 839 NPETTGEEDEEEPEMPVGPRPRP 861
            P    E   +    PVG + RP
Sbjct: 815 RPLVV-ELGRDGARGPVGGKARP 836



 Score =  216 bits (550), Expect = 2e-55
 Identities = 179/716 (25%), Positives = 322/716 (44%), Gaps = 113/716 (15%)

Query: 64   LMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPR------ALLCLTLKNPIRRAC 117
            L G  G AT+    +   + Q  GK + +        PR      ++ CL+  N +RR C
Sbjct: 1084 LTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFC 1143

Query: 118  ISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK 177
              IV  + FE++IL+ I  + +ALA   P   D     N+ L+ ++Y+F  +FT E  +K
Sbjct: 1144 HYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPR--NNALKYLDYIFTGVFTFEMVIK 1201

Query: 178  VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR 237
            +I  GLL HP AY R+ WN+LDF IVV G   A     +K    N          +K+LR
Sbjct: 1202 MIDLGLLLHPGAYFRDLWNILDF-IVVSGALVAFAFSGSKGKDINT---------IKSLR 1251

Query: 238  AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT 297
              RVLRPL+ +  +P L+ V + ++ ++  +L+I ++ +  + I+A+I ++LF GK    
Sbjct: 1252 VLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFF-Y 1310

Query: 298  CYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVF 357
            C ++    +            E    +  Q        W   K    ++DN  +A+LT+F
Sbjct: 1311 CTDESKELERDCRGQYLDYEKEEVEAQPRQ--------W---KKYDFHYDNVLWALLTLF 1359

Query: 358  QCITMEGWTDVLYWVNDAVGRDWP---------WIYFVTLIIIGSFFVLNLVLGVLSGEF 408
               T EGW  VL    DA   +            I++V   ++  FF +N+ + ++   F
Sbjct: 1360 TVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITF 1419

Query: 409  SKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPT 468
             ++       GD  K+  +  LE++ +  +D+   A               KP    MP 
Sbjct: 1420 QEQ-------GD--KVMSECSLEKNERACIDFAISA---------------KPLTRYMP- 1454

Query: 469  SETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYW 528
                                          +++ S  ++ W           V S  F +
Sbjct: 1455 ------------------------------QNRQSFQYKTW---------TFVVSPPFEY 1475

Query: 529  LVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLF 588
             ++ ++ LNT+ +  + Y+ P     +    N    ++F+ E +LK+ + G+  YF   +
Sbjct: 1476 FIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAW 1535

Query: 589  NRFDCFVVCGGILETILVE-TKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNS 647
            N FD   V G I + ++ E  +  + + +S LR  R  R+ K+ R   ++  L+ + + S
Sbjct: 1536 NVFDFVTVLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQS 1595

Query: 648  VRSIASLLLLLFLFIIIFSLLGMQLFGG-KFNFDEMQTRRSTFDNFPQSLLTVFQILTGE 706
             +++  + LL+ +   I++++GMQ+FG    + D    R + F  F Q+L+ +F+  TGE
Sbjct: 1596 FKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGE 1655

Query: 707  DWNSVMYDGIMAYGGPSFPGMLVC------IYFI-ILFICGNYILLNVFLAIAVDN 755
             W+ +M   +             C       YF+  +F+C ++++LN+F+A+ +DN
Sbjct: 1656 AWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1710



 Score =  127 bits (319), Expect = 1e-28
 Identities = 160/728 (21%), Positives = 303/728 (41%), Gaps = 146/728 (20%)

Query: 526  FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQ- 581
            F ++++  +  N + +A E +        ++E  D      + +F  E  +K+ +LG   
Sbjct: 97   FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156

Query: 582  ---AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLS 638
               +Y  + +N  D  VV  GIL T   +        +  LR VR+LR  K+     SL 
Sbjct: 157  HKGSYLRNGWNVMDFVVVLTGILATAGTD------FDLRTLRAVRVLRPLKLVSGIPSLQ 210

Query: 639  NLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF------------------- 679
             ++ S++ ++  +  + LLLF  I++F+++G++ + GKF+                    
Sbjct: 211  VVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAEPVGDFPCGK 270

Query: 680  --------DEMQTRR---------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGP 722
                     + + R          + FDN   ++LTVFQ +T E W  ++Y+   A G  
Sbjct: 271  EAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNT 330

Query: 723  SFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTA 782
                    +YFI L I G++ +LN+ L +     A             +E+ER +  R  
Sbjct: 331  -----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERERVENRRAF 372

Query: 783  SPEKKQELVEKPAVG------ESKEEKIELKSITADGESP------PATKINMDDLQPNE 830
               ++Q+ +E+   G      +++E  +  +   A+ +SP       ATK + +DL   E
Sbjct: 373  LKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAE 432

Query: 831  NEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFR 890
                           ED       VG    P +   LK       E+S++F       FR
Sbjct: 433  EG-------------EDRFADLCAVGS---PFARASLKSGKT---ESSSYFR-RKEKMFR 472

Query: 891  LQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIAL 950
                R+V    F  ++L  + L+++ +A     Q        L++ + VF  +F  E++L
Sbjct: 473  FFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTT-TLYFAEFVFLGLFLTEMSL 531

Query: 951  KMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRPLR 1007
            KM  YG  L   S+ R+ FN  D  V+  S+       I+  +   + +LR LR+LR  +
Sbjct: 532  KM--YG--LGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFK 587

Query: 1008 AINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEA 1067
                   L+++V  +  ++++I +++ +  L   +FA +G+QLF G+             
Sbjct: 588  VTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQF------------ 635

Query: 1068 ECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDS 1127
                    ++D             E    +FD   AA++ +F + T E W  ++Y  I+S
Sbjct: 636  -------NFQD-------------ETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIES 675

Query: 1128 HTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE--QEYKNCELDKN 1185
                   +++     S +FI+  +   + ++N+F+   +       E  ++ +  E   N
Sbjct: 676  QGGVSKGMFS-----SFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEMEEAAN 730

Query: 1186 QRQCVEYA 1193
            Q+  ++ A
Sbjct: 731  QKLALQKA 738



 Score =  116 bits (290), Expect = 3e-25
 Identities = 94/326 (28%), Positives = 163/326 (50%), Gaps = 24/326 (7%)

Query: 879  AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936
            + F+FS +N  R    RI     F  +IL  I+ + I LA E   P    +  +  L   
Sbjct: 74   SLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDT 133

Query: 937  DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKI 996
            +  F  IF  E  +K+ A G   HKGS+ RN +N++D +VV   +++    +     ++ 
Sbjct: 134  EPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA---TAGTDFDLRT 190

Query: 997  LRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLY 1056
            LR +RVLRPL+ ++    L+ V++ +  A+  +  I ++      MFA IG++ + GK +
Sbjct: 191  LRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFH 250

Query: 1057 -TCSDSSKQTEAECKGNYITYKDGEV---DHPIIQPRSWENSKF---DFDNVLAAMMALF 1109
              C  +S  T+AE  G++   K+      +        W    F   +FDN+L A++ +F
Sbjct: 251  KACFPNS--TDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVF 308

Query: 1110 TVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTF 1169
               T EGW ++LY + D+     G  +N+     ++FI  III +FFM+N+ +G +   F
Sbjct: 309  QCITMEGWTDILYNTNDA----AGNTWNW-----LYFIPLIIIGSFFMLNLVLGVLSGEF 359

Query: 1170 QEQGEQ-EYKNCELDKNQRQCVEYAL 1194
             ++ E+ E +   L   ++Q +E  L
Sbjct: 360  AKERERVENRRAFLKLRRQQQIEREL 385



 Score =  109 bits (273), Expect = 3e-23
 Identities = 76/303 (25%), Positives = 134/303 (44%), Gaps = 63/303 (20%)

Query: 1215 VVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFK 1274
            +V +  F +++  ++ LNT+C+AM HY Q       +     +F GLF  EM LK+    
Sbjct: 478  MVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLG 537

Query: 1275 PKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPA 1334
            P+ YF                              ++N FD  ++VGS+ ++    + P 
Sbjct: 538  PRSYFRS----------------------------SFNCFDFGVIVGSVFEVVWAAIKPG 569

Query: 1335 EHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALL 1394
                          S   I+  R  R++R+ K+      +R L+ + + S +++  +  L
Sbjct: 570  --------------SSFGISVLRALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFL 615

Query: 1395 IVMLFFIYAVIGMQVF-GKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLAC 1453
            + +   ++A++GMQ+F G+    D T      NF TFP A+L +F+  TGE W  +M   
Sbjct: 616  LFLFIVVFALLGMQLFGGQFNFQDETP---TTNFDTFPAAILTVFQILTGEDWNAVMYHG 672

Query: 1454 MPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF---DYL 1510
            +       ES+   S          F+ FYFI   +   + ++N+F+A+ +DN      L
Sbjct: 673  I-------ESQGGVSK-------GMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQEL 718

Query: 1511 TRD 1513
            T+D
Sbjct: 719  TKD 721



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 70/295 (23%), Positives = 130/295 (44%), Gaps = 66/295 (22%)

Query: 125  PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184
            PFE  I+  I  N V L +      D        L+ +  +F  +F++E  LK+IA+G+L
Sbjct: 1472 PFEYFIMAMIALNTVVLMMKF---YDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVL 1528

Query: 185  FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244
                 Y R+ WN+ DF+ V+  +   ++ +  + +            ++  LR FR  R 
Sbjct: 1529 ----NYFRDAWNVFDFVTVLGSITDILVTEIAETNNF---------INLSFLRLFRAARL 1575

Query: 245  LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304
            ++L+    +++++L + +++   L ++ LL+  +  IYAIIG+++F              
Sbjct: 1576 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-------------- 1621

Query: 305  ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364
             ++  +DD S                         +H   NF  F  A++ +F+  T E 
Sbjct: 1622 GNIALDDDTSI-----------------------NRHN--NFRTFLQALMLLFRSATGEA 1656

Query: 365  WTDVLYWV--NDAV---------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408
            W +++     N A          G D+ + YFV+ I + SF +LNL + V+   F
Sbjct: 1657 WHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1711



 Score = 58.5 bits (140), Expect = 7e-08
 Identities = 65/329 (19%), Positives = 118/329 (35%), Gaps = 108/329 (32%)

Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273
            FEY++   I+ N I LA++ +   G        ++     F G+F  E  +K+IA    F
Sbjct: 97   FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156

Query: 1274 KPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNP 1333
                Y  + WNV DF++V+  I+                                     
Sbjct: 157  HKGSYLRNGWNVMDFVVVLTGIL------------------------------------- 179

Query: 1334 AEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVAL 1393
                       A   +   +   R  RV+R +KL+S    ++ +L + +K+   L  + L
Sbjct: 180  -----------ATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGL 228

Query: 1394 LIVMLFFIYAVIGMQV----FGKIALNDTTEIN--------------------------- 1422
            L+     ++A+IG++     F K    ++T+                             
Sbjct: 229  LLFFAILMFAIIGLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWP 288

Query: 1423 ----RNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS 1478
                   NF     A+L +F+C T E W DI+                N+ +     G++
Sbjct: 289  GPNFGITNFDNILFAILTVFQCITMEGWTDILY---------------NTNDA---AGNT 330

Query: 1479 FAVFYFISFYMLCAFLIINLFVAVIMDNF 1507
            +   YFI   ++ +F ++NL + V+   F
Sbjct: 331  WNWLYFIPLIIIGSFFMLNLVLGVLSGEF 359


>gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E
            subunit [Homo sapiens]
          Length = 2270

 Score =  732 bits (1890), Expect = 0.0
 Identities = 393/861 (45%), Positives = 548/861 (63%), Gaps = 66/861 (7%)

Query: 833  DKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQ 892
            D    P  E    EDEEE E     + +       +E    M   S+ FIFS+ N  R  
Sbjct: 1093 DGEASPLKEAEIREDEEEVEKKKQKKEK-------RETGKAMVPHSSMFIFSTTNPIRRA 1145

Query: 893  CHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKM 952
            CH IVN   F   IL  I  SSI+LAAEDPV   S RN +L YFD VFT +FT E+ +KM
Sbjct: 1146 CHYIVNLRYFEMCILLVIAASSIALAAEDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKM 1205

Query: 953  TAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA-------INVVKILRVLRVLRP 1005
               G  L  GS+ R+ +NILD +VV  +L++F + ++        I  +K LRVLRVLRP
Sbjct: 1206 IDQGLILQDGSYFRDLWNILDFVVVVGALVAFALANALGTNKGRDIKTIKSLRVLRVLRP 1265

Query: 1006 LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT 1065
            L+ I R   LK V  CV  +++ + NI+IV  L  F+FA I VQLFKGK + C+DSSK T
Sbjct: 1266 LKTIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKDT 1325

Query: 1066 EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI 1125
            E EC GNY+ ++  +++   ++ R W+  +F +DN++ A++ LFTVST EGWP++L  S+
Sbjct: 1326 EKECIGNYVDHEKNKME---VKGREWKRHEFHYDNIIWALLTLFTVSTGEGWPQVLQHSV 1382

Query: 1126 DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKN 1185
            D   ED+GP  + R+E+SIF+++Y ++  FF +NIFV  +I+TFQEQG++  + C L+KN
Sbjct: 1383 DVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLEKN 1442

Query: 1186 QRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQ 1243
            +R C+++A+ A+PL RY+P+N+H  QY+VW+ V S  FEY +  +I LNT+ L M++Y  
Sbjct: 1443 ERACIDFAISAKPLTRYMPQNRHTFQYRVWHFVVSPSFEYTIMAMIALNTVVLMMKYYSA 1502

Query: 1244 SCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSET 1303
             C +++A+  LN+ FT +F++E +LK+IAF              FL              
Sbjct: 1503 PCTYELALKYLNIAFTMVFSLECVLKVIAF-------------GFL-------------- 1535

Query: 1304 NHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMR 1363
             +YF D WN FD + V+GSI +I +T+         S  +N    S  +++F +LFR  R
Sbjct: 1536 -NYFRDTWNIFDFITVIGSITEIILTD---------SKLVNT---SGFNMSFLKLFRAAR 1582

Query: 1364 LVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINR 1423
            L+KLL +G  IR LLWTF++SF+ALPYV LLI MLFFIYA+IGMQVFG I L++ + INR
Sbjct: 1583 LIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLDEESHINR 1642

Query: 1424 NNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESE-PSNSTEGETPCGSSFAVF 1482
            +NNF++F  +++LLFR ATGEAWQ+IML+C+  K C P++  PS   E E  CG+  A  
Sbjct: 1643 HNNFRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGCEPDTTAPSGQNENER-CGTDLAYV 1701

Query: 1483 YFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKH 1542
            YF+SF   C+FL++NLFVAVIMDNF+YLTRD SILGPHHLDEF R+WAEYD  A GRI +
Sbjct: 1702 YFVSFIFFCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFVRVWAEYDRAACGRIHY 1761

Query: 1543 LDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKT 1602
             ++  +L  + PPLG GK CP +VA KRLV MNMP+  D TV F +TL AL+RTAL IK 
Sbjct: 1762 TEMYEMLTLMSPPLGLGKRCPSKVAYKRLVLMNMPVAEDMTVHFTSTLMALIRTALDIKI 1821

Query: 1603 E---GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKF 1659
                 + +Q + EL+     IW   S K+LD +VP     ++TVGK YA  +I +Y+++ 
Sbjct: 1822 AKGGADRQQLDSELQKETLAIWPHLSQKMLDLLVPMPKASDLTVGKIYAAMMIMDYYKQS 1881

Query: 1660 KKRKEQGLVGKPSQRNALSLQ 1680
            K +K++  +    Q+NA   Q
Sbjct: 1882 KVKKQRQQL--EEQKNAPMFQ 1900



 Score =  630 bits (1626), Expect = e-180
 Identities = 359/754 (47%), Positives = 468/754 (62%), Gaps = 35/754 (4%)

Query: 60  RQAKLMGSAGNATISTVSSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRA 116
           RQ   + ++G A     +  QR R    Y   P +Q   T  R   +L      N +R+ 
Sbjct: 25  RQGTPVPASGQAAAYKQTKAQRARTMALYNPIPVRQNCFTVNR---SLFIFGEDNIVRKY 81

Query: 117 CISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFL 176
              +++W PFE +IL TI ANC+ LA+    PEDD    +  LE+ E  F+ IF  EA +
Sbjct: 82  AKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGI 141

Query: 177 KVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKAL 236
           K++A G +FH  +YLRNGWN++DFI+V+ G+       AT     N         D++ L
Sbjct: 142 KIVALGFIFHKGSYLRNGWNVMDFIVVLSGIL------ATAGTHFNT------HVDLRTL 189

Query: 237 RAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHK 296
           RA RVLRPL+LVSG+PSLQ+VL SI+KAMVPLL I LL+ F I+++AIIGLE + GK+H+
Sbjct: 190 RAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHR 249

Query: 297 TCY-NQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLT 355
            C+ N  GI +    D P PC ++      C  G  CK  W GP  GIT FDN  FA+LT
Sbjct: 250 ACFMNNSGILE--GFDPPHPCGVQG-----CPAGYECKD-WIGPNDGITQFDNILFAVLT 301

Query: 356 VFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKA 415
           VFQCITMEGWT VLY  NDA+G  W W+YF+ LIIIGSFFVLNLVLGVLSGEF+KERE+ 
Sbjct: 302 VFQCITMEGWTTVLYNTNDALGATWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERERV 361

Query: 416 KARGDFQKLREKQQLEEDLKGYLDWITQAEDI--DPENEDEGMDE-EKPRNMSMPTSETE 472
           + R  F KLR +QQ+E +L GY  WI +AE++    EN++ G    E  R  ++  S TE
Sbjct: 362 ENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTE 421

Query: 473 SVNTENVAGGDIEGENCGARLAHRISKSKFS---RYWRRWNRFCRRKCRAAVKSNVFYWL 529
           ++  ++     ++  + G  LA    KS       Y+R   R  R   R  VKS VFYW+
Sbjct: 422 AMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRISIRHMVKSQVFYWI 481

Query: 530 VIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFN 589
           V+ LV LNT  +A  H+NQP WLT +   A    L LF  EM LKMY +G + YF S FN
Sbjct: 482 VLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRLYFHSSFN 541

Query: 590 RFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVR 649
            FD  V  G I E +    +  +  GISVLR +RLLRIFKIT+YW SL NLV SL++S++
Sbjct: 542 CFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSSMK 601

Query: 650 SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWN 709
           SI SLL LLFLFI++F+LLGMQLFGG+FNF++  T  + FD FP +++TVFQILTGEDWN
Sbjct: 602 SIISLLFLLFLFIVVFALLGMQLFGGRFNFND-GTPSANFDTFPAAIMTVFQILTGEDWN 660

Query: 710 SVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEE 769
            VMY+GI + GG S  GM   IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT  ++EE
Sbjct: 661 EVMYNGIRSQGGVS-SGMWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEE 719

Query: 770 EEEKERKKLARTASPEKKQELVEKPAVGESKEEK 803
           EE   +K   + A           P++   +  +
Sbjct: 720 EEAFNQKHALQKAKEVSPMSAPNMPSIERDRRRR 753



 Score =  220 bits (561), Expect = 1e-56
 Identities = 185/707 (26%), Positives = 329/707 (46%), Gaps = 124/707 (17%)

Query: 80   QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139
            ++K+Q   K +K+ +  A  P  ++   +  NPIRRAC  IV  + FE+ ILL I A+ +
Sbjct: 1112 EKKKQ---KKEKRETGKAMVPHSSMFIFSTTNPIRRACHYIVNLRYFEMCILLVIAASSI 1168

Query: 140  ALAIYIPFPEDDSNATNSNLERV----EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGW 195
            ALA       +D   TNS   +V    +Y+F  +FT E  +K+I  GL+    +Y R+ W
Sbjct: 1169 ALAA------EDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKMIDQGLILQDGSYFRDLW 1222

Query: 196  NLLDFIIVVVGLFSAILEQATKADGANALG-GKGAGF-DVKALRAFRVLRPLRLVSGVPS 253
            N+LDF++VV  L +  L        ANALG  KG     +K+LR  RVLRPL+ +  +P 
Sbjct: 1223 NILDFVVVVGALVAFAL--------ANALGTNKGRDIKTIKSLRVLRVLRPLKTIKRLPK 1274

Query: 254  LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313
            L+ V + ++ ++  + +I ++    + I+A+I ++LF GK    C +        ++D  
Sbjct: 1275 LKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFF-YCTDS-------SKDTE 1326

Query: 314  SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373
              C    G+    +   +   G +  +H   ++DN  +A+LT+F   T EGW  VL    
Sbjct: 1327 KEC---IGNYVDHEKNKMEVKGREWKRHEF-HYDNIIWALLTLFTVSTGEGWPQVLQHSV 1382

Query: 374  DAVGRD---------WPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKL 424
            D    D            I++V   ++  FF +N+ + ++   F ++       GD  K+
Sbjct: 1383 DVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KM 1433

Query: 425  REKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDI 484
             E+  LE++ +  +D+   A               KP    MP                 
Sbjct: 1434 MEECSLEKNERACIDFAISA---------------KPLTRYMP----------------- 1461

Query: 485  EGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASE 544
                          +++ +  +R W+          V S  F + ++ ++ LNT+ +  +
Sbjct: 1462 --------------QNRHTFQYRVWH---------FVVSPSFEYTIMAMIALNTVVLMMK 1498

Query: 545  HYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETI 604
            +Y+ P          N A   +F+ E +LK+ + G   YF   +N FD   V G I E I
Sbjct: 1499 YYSAPCTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEII 1558

Query: 605  LVETKIMSPLG--ISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFI 662
            L ++K+++  G  +S L+  R  R+ K+ R   ++  L+ + + S +++  + LL+ +  
Sbjct: 1559 LTDSKLVNTSGFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLF 1618

Query: 663  IIFSLLGMQLFGG-KFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG- 720
             I++++GMQ+FG  K + +    R + F +F  SL+ +F+  TGE W  +M   +   G 
Sbjct: 1619 FIYAIIGMQVFGNIKLDEESHINRHNNFRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGC 1678

Query: 721  -----GPSFPGM-------LVCIYFIILFICGNYILLNVFLAIAVDN 755
                  PS           L  +YF+      ++++LN+F+A+ +DN
Sbjct: 1679 EPDTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMDN 1725



 Score =  180 bits (457), Expect = 1e-44
 Identities = 172/726 (23%), Positives = 305/726 (42%), Gaps = 169/726 (23%)

Query: 879  AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936
            + FIF  +N  R    ++++   F  +IL  I+ + I LA E   P    +  +  L   
Sbjct: 68   SLFIFGEDNIVRKYAKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKT 127

Query: 937  DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVV-SVSLISFGIQSSAINVVK 995
            +  F  IF  E  +K+ A G   HKGS+ RN +N++D +VV S  L + G   +    ++
Sbjct: 128  EPYFIGIFCFEAGIKIVALGFIFHKGSYLRNGWNVMDFIVVLSGILATAGTHFNTHVDLR 187

Query: 996  ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055
             LR +RVLRPL+ ++    L+ V++ +  A+  +  I ++      MFA IG++ + GKL
Sbjct: 188  TLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKL 247

Query: 1056 YTCSDSSKQTEAECKGNYITYKDG-EVDHPI--------IQPRSW---ENSKFDFDNVLA 1103
            +            C  N     +G +  HP          + + W    +    FDN+L 
Sbjct: 248  HRA----------CFMNNSGILEGFDPPHPCGVQGCPAGYECKDWIGPNDGITQFDNILF 297

Query: 1104 AMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVG 1163
            A++ +F   T EGW  +LY + D+     G  +N+     ++FI  III +FF++N+ +G
Sbjct: 298  AVLTVFQCITMEGWTTVLYNTNDA----LGATWNW-----LYFIPLIIIGSFFVLNLVLG 348

Query: 1164 ------------------FVIVTFQEQGEQEYKNCEL----------------------- 1182
                              F+ +  Q+Q E+E                             
Sbjct: 349  VLSGEFAKERERVENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALE 408

Query: 1183 -----------------DKNQRQCVEYALKARPLRRYIPKN---------QHQYK----- 1211
                             D +   CV+ +    PL R   K+         +H+ +     
Sbjct: 409  VLRRATIKRSRTEAMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRIS 468

Query: 1212 VWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLI 1271
            + ++V S  F +++  L+ LNT C+A+ H+ Q       +     LF GLF +EM LK+ 
Sbjct: 469  IRHMVKSQVFYWIVLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMY 528

Query: 1272 AFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEV 1331
               P+ YF                              ++N FD  + VGSI ++     
Sbjct: 529  GMGPRLYFHS----------------------------SFNCFDFGVTVGSIFEVVWAIF 560

Query: 1332 NPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1391
             P               +   I+  R  R++R+ K+      +R L+ + + S +++  +
Sbjct: 561  RPG--------------TSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSSMKSIISL 606

Query: 1392 ALLIVMLFFIYAVIGMQVF-GKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIM 1450
              L+ +   ++A++GMQ+F G+   ND T    + NF TFP A++ +F+  TGE W ++M
Sbjct: 607  LFLLFLFIVVFALLGMQLFGGRFNFNDGTP---SANFDTFPAAIMTVFQILTGEDWNEVM 663

Query: 1451 LACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF--- 1507
               +              ++G    G  ++  YFI   +   + ++N+F+A+ +DN    
Sbjct: 664  YNGI-------------RSQGGVSSG-MWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANA 709

Query: 1508 DYLTRD 1513
              LT+D
Sbjct: 710  QELTKD 715



 Score =  135 bits (340), Expect = 4e-31
 Identities = 154/731 (21%), Positives = 303/731 (41%), Gaps = 140/731 (19%)

Query: 526  FYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKA---LLALFTAEMLLKMYSLGL-- 580
            F ++++  +  N + +A E +   +  T +     K     + +F  E  +K+ +LG   
Sbjct: 91   FEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGIKIVALGFIF 150

Query: 581  --QAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLS 638
               +Y  + +N  D  VV  GIL T    T   + + +  LR VR+LR  K+     SL 
Sbjct: 151  HKGSYLRNGWNVMDFIVVLSGILAT--AGTHFNTHVDLRTLRAVRVLRPLKLVSGIPSLQ 208

Query: 639  NLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFN-------------FDEMQTR 685
             ++ S++ ++  +  + LLLF  I++F+++G++ + GK +             FD     
Sbjct: 209  IVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHRACFMNNSGILEGFDPPHPC 268

Query: 686  R--------------------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP 725
                                 + FDN   ++LTVFQ +T E W +V+Y+   A G     
Sbjct: 269  GVQGCPAGYECKDWIGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTNDALGAT--- 325

Query: 726  GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE 785
                 +YFI L I G++ +LN+ L +     A             +E+ER +  R     
Sbjct: 326  --WNWLYFIPLIIIGSFFVLNLVLGVLSGEFA-------------KERERVENRRAFMKL 370

Query: 786  KKQELVEKPAVGE----SKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPE 841
            ++Q+ +E+   G      K E++ L     +  +     +    ++ +  E  +      
Sbjct: 371  RRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTEAMT------ 424

Query: 842  TTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTI 901
                +  +E  + +     PL+   +K   V        +        R+    +V   +
Sbjct: 425  ---RDSSDEHCVDISSVGTPLARASIKSAKVD----GVSYFRHKERLLRISIRHMVKSQV 477

Query: 902  FTNLILFFILLSSISLAAEDPVQHTS--FRNHILFYFDIVFTTIFTIEIALKMTAYGAFL 959
            F  ++L  + L++  +A    V H    +  H+L+Y + +F  +F +E++LKM   G  L
Sbjct: 478  FYWIVLSLVALNTACVAI---VHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRL 534

Query: 960  HKGSFCRNYFNILD--LLVVSVSLISFGIQSSAINV-VKILRVLRVLRPLRAINRAKGLK 1016
                +  + FN  D  + V S+  + + I     +  + +LR LR+LR  +       L+
Sbjct: 535  ----YFHSSFNCFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLR 590

Query: 1017 HVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITY 1076
            ++V  +  ++++I +++ +  L   +FA +G+QLF G+                     +
Sbjct: 591  NLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGRF-------------------NF 631

Query: 1077 KDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIY 1136
             DG                 +FD   AA+M +F + T E W E++Y  I S       ++
Sbjct: 632  NDG-------------TPSANFDTFPAAIMTVFQILTGEDWNEVMYNGIRSQGGVSSGMW 678

Query: 1137 NYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEYKNCELDKNQRQ 1188
            +     +I+FI+  +   + ++N+F+   +        +T  EQ E+E        NQ+ 
Sbjct: 679  S-----AIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEE------AFNQKH 727

Query: 1189 CVEYALKARPL 1199
             ++ A +  P+
Sbjct: 728  ALQKAKEVSPM 738



 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 72/302 (23%), Positives = 131/302 (43%), Gaps = 74/302 (24%)

Query: 126  FEIIILLTIFANCVALAI-YIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184
            FE  I+  I  N V L + Y   P     A    L+ +   F ++F++E  LKVIA+G L
Sbjct: 1480 FEYTIMAMIALNTVVLMMKYYSAPCTYELA----LKYLNIAFTMVFSLECVLKVIAFGFL 1535

Query: 185  FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244
                 Y R+ WN+ DFI V+  +   IL  +   + +        GF++  L+ FR  R 
Sbjct: 1536 ----NYFRDTWNIFDFITVIGSITEIILTDSKLVNTS--------GFNMSFLKLFRAARL 1583

Query: 245  LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304
            ++L+    +++++L + +++   L ++ LL+  +  IYAIIG+++F              
Sbjct: 1584 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-------------- 1629

Query: 305  ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364
             ++  ++       E+   R                    NF +F  +++ +F+  T E 
Sbjct: 1630 GNIKLDE-------ESHINRH------------------NNFRSFFGSLMLLFRSATGEA 1664

Query: 365  WTDVLYWV------------------NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406
            W +++                     N+  G D  ++YFV+ I   SF +LNL + V+  
Sbjct: 1665 WQEIMLSCLGEKGCEPDTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMD 1724

Query: 407  EF 408
             F
Sbjct: 1725 NF 1726


>gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo
            sapiens]
          Length = 1977

 Score =  323 bits (829), Expect = 9e-88
 Identities = 255/885 (28%), Positives = 433/885 (48%), Gaps = 109/885 (12%)

Query: 754  DNLADAESLTSAQKEEEEEKERKKLARTASPEKK--------QELVEKPAV--------G 797
            +N     +L    K     KE+ K++   S   K        Q  +  P++        G
Sbjct: 1024 ENYISNHTLAEMSKGHNFLKEKDKISGFGSSVDKHLMEDSDGQSFIHNPSLTVTVPIAPG 1083

Query: 798  ESKEEKIELKSITADGESPPATKINMDDLQPNE-NEDKSPYPNPETTGEEDEEEPEMPVG 856
            ES  E +  + +++D +S   +K+ ++    +E +   +P P     GEE E EP     
Sbjct: 1084 ESDLENMNAEELSSDSDSE-YSKVRLNRSSSSECSTVDNPLPGE---GEEAEAEPMNSDE 1139

Query: 857  PRPRPLSELHLKEKAVPMPEASAFFIFSSNNRF----RLQCHRIVNDTIFTNLILFFILL 912
            P      E    +  V         I S   +     R  C++IV  + F + I+  ILL
Sbjct: 1140 P------EACFTDGCVRRFSCCQVNIESGKGKIWWNIRKTCYKIVEHSWFESFIVLMILL 1193

Query: 913  SSISLAAEDP-VQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNI 971
            SS +LA ED  ++       IL Y D +FT IF +E+ LK  AYG      ++  N +  
Sbjct: 1194 SSGALAFEDIYIERKKTIKIILEYADKIFTYIFILEMLLKWIAYGY----KTYFTNAWCW 1249

Query: 972  LDLLVVSVSLISFGIQS---SAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRT 1028
            LD L+V VSL++    +   S +  +K LR LR LRPLRA++R +G++ VV  +  AI +
Sbjct: 1250 LDFLIVDVSLVTLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPS 1309

Query: 1029 IGNIVIVTTLLQFMFACIGVQLFKGKLYTC---SDSSKQTEAECKGNYITYKDGEVDHPI 1085
            I N+++V  +   +F+ +GV LF GK Y C   +D S+   ++       +    V   +
Sbjct: 1310 IMNVLLVCLIFWLIFSIMGVNLFAGKFYECINTTDGSRFPASQVPNRSECFALMNVSQNV 1369

Query: 1086 IQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIF 1145
                 W+N K +FDNV    ++L  V+TF+GW  ++Y ++DS   DK P Y Y + + I+
Sbjct: 1370 ----RWKNLKVNFDNVGLGYLSLLQVATFKGWTIIMYAAVDSVNVDKQPKYEYSLYMYIY 1425

Query: 1146 FIIYIIIIAFFMMNIFVGFVIVTFQEQ----GEQEYKNCELDKNQRQCVEYALKARPLRR 1201
            F+++II  +FF +N+F+G +I  F +Q    G Q+    E  K     ++     +P ++
Sbjct: 1426 FVVFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKP-QK 1484

Query: 1202 YIPK--NQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFT 1259
             IP+  N+ Q  ++ +V +  F+  + VLI LN + + ++  GQS      +  +N++F 
Sbjct: 1485 PIPRPGNKIQGCIFDLVTNQAFDISIMVLICLNMVTMMVEKEGQSQHMTEVLYWINVVFI 1544

Query: 1260 GLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSE-TNHYFCDAWNTFDALI 1318
             LFT E +LKLI+ +   YF+  WN+FDF++VI SI+ + L++    YF           
Sbjct: 1545 ILFTGECVLKLISLR-HYYFTVGWNIFDFVVVIISIVGMFLADLIETYF----------- 1592

Query: 1319 VVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLL 1378
                                 SP++             RL R+ R+++L+   +GIRTLL
Sbjct: 1593 --------------------VSPTL---------FRVIRLARIGRILRLVKGAKGIRTLL 1623

Query: 1379 WTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLF 1438
            +  + S  AL  + LL+ ++ FIYA+ GM  F  +   D   IN   NF+TF  +++ LF
Sbjct: 1624 FALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKED--GINDMFNFETFGNSMICLF 1681

Query: 1439 RCATGEAWQDIMLACMPGK--KCAPES-EPSNSTEGETPCGS-SFAVFYFISFYMLCAFL 1494
            +  T   W  ++   +  K   C P+   P +S EG+  CG+ S  +FYF+S+ ++   +
Sbjct: 1682 QITTSAGWDGLLAPILNSKPPDCDPKKVHPGSSVEGD--CGNPSVGIFYFVSYIIISFLV 1739

Query: 1495 IINLFVAVIMDNFDYLTRD-WSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQ 1553
            ++N+++AVI++NF   T +    L     + F  +W ++DP+A   I+   +      + 
Sbjct: 1740 VVNMYIAVILENFSVATEESTEPLSEDDFEMFYEVWEKFDPDATQFIEFSKLSDFAAALD 1799

Query: 1554 PPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL 1598
            PPL   K  P++V   +L++M++P+ S   +     LFA  +  L
Sbjct: 1800 PPLLIAK--PNKV---QLIAMDLPMVSGDRIHCLDILFAFTKRVL 1839



 Score =  174 bits (441), Expect = 8e-43
 Identities = 176/696 (25%), Positives = 293/696 (42%), Gaps = 132/696 (18%)

Query: 113  IRRACISIVEWKPFEIIILLTIFANCVALA---IYIPFPEDDSNATNSNLERVEYLFLII 169
            IR+ C  IVE   FE  I+L I  +  ALA   IYI    +        LE  + +F  I
Sbjct: 1170 IRKTCYKIVEHSWFESFIVLMILLSSGALAFEDIYI----ERKKTIKIILEYADKIFTYI 1225

Query: 170  FTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGA 229
            F +E  LK IAYG       Y  N W  LDF+IV V L + +         AN LG    
Sbjct: 1226 FILEMLLKWIAYGY----KTYFTNAWCWLDFLIVDVSLVTLV---------ANTLGYSDL 1272

Query: 230  GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLEL 289
            G  +K+LR  R LRPLR +S    ++VV+N++I A+  ++++ L+ L   +I++I+G+ L
Sbjct: 1273 G-PIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNL 1331

Query: 290  FMGKMHKTCYNQEGIADVPAEDDP--SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFD 347
            F GK ++ C N    +  PA   P  S C       +  +        W   K    NFD
Sbjct: 1332 FAGKFYE-CINTTDGSRFPASQVPNRSECFALMNVSQNVR--------WKNLK---VNFD 1379

Query: 348  NFAFAMLTVFQCITMEGWTDVLYWVNDAVGRD---------WPWIYFVTLIIIGSFFVLN 398
            N     L++ Q  T +GWT ++Y   D+V  D         + +IYFV  II GSFF LN
Sbjct: 1380 NVGLGYLSLLQVATFKGWTIIMYAAVDSVNVDKQPKYEYSLYMYIYFVVFIIFGSFFTLN 1439

Query: 399  LVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDE 458
            L +GV+   F+++++K   + D     E+++    +K       Q     P N+ +G   
Sbjct: 1440 LFIGVIIDNFNQQKKKLGGQ-DIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKIQGCIF 1498

Query: 459  EKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCR 518
            +   N +   S    +              C   +   + K   S++             
Sbjct: 1499 DLVTNQAFDISIMVLI--------------CLNMVTMMVEKEGQSQH------------- 1531

Query: 519  AAVKSNVFYWLVIFLVFLNT------LTIASEHYNQPNWLTEVQDTANKALLALFTAEML 572
                + V YW+ +  + L T      L     +Y    W          +++ +F A++ 
Sbjct: 1532 ---MTEVLYWINVVFIILFTGECVLKLISLRHYYFTVGWNIFDFVVVIISIVGMFLADL- 1587

Query: 573  LKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITR 632
                   ++ YFVS                          P    V+R  R+ RI ++ +
Sbjct: 1588 -------IETYFVS--------------------------PTLFRVIRLARIGRILRLVK 1614

Query: 633  YWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNF 692
                +  L+ +L+ S+ ++ ++ LLLFL + I+++ GM  F      D +      F+ F
Sbjct: 1615 GAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEDGIND-MFNFETF 1673

Query: 693  PQSLLTVFQILTGEDWNSVM----------YDGIMAYGGPSFPG-----MLVCIYFIILF 737
              S++ +FQI T   W+ ++           D    + G S  G      +   YF+   
Sbjct: 1674 GNSMICLFQITTSAGWDGLLAPILNSKPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYI 1733

Query: 738  ICGNYILLNVFLAIAVDNLADA-ESLTSAQKEEEEE 772
            I    +++N+++A+ ++N + A E  T    E++ E
Sbjct: 1734 IISFLVVVNMYIAVILENFSVATEESTEPLSEDDFE 1769



 Score =  160 bits (404), Expect = 2e-38
 Identities = 106/355 (29%), Positives = 180/355 (50%), Gaps = 50/355 (14%)

Query: 103 ALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERV 162
           AL  L+  +P+RR  I I+    F ++I+ TI  NC+ + +  P P+   N        V
Sbjct: 105 ALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMNNP-PDWTKN--------V 155

Query: 163 EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGAN 222
           EY F  I+T E+ +K++A G       +LR+ WN LDF+++V    +  +          
Sbjct: 156 EYTFTGIYTFESLVKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVN--------- 206

Query: 223 ALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIY 282
            LG      +V ALR FRVLR L+ +S +P L+ ++ ++I+++  L  + +L +F + ++
Sbjct: 207 -LG------NVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVF 259

Query: 283 AIIGLELFMGKMHKTCY-----NQEGIADV-----------------PAEDDPSPCALET 320
           A+IGL+LFMG +   C+     N E +  +                     D   C   T
Sbjct: 260 ALIGLQLFMGNLKHKCFRNSLENNETLESIMNTLESEEDFRKYFYYLEGSKDALLCGFST 319

Query: 321 GHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDW 380
             G QC  G  C      P +G T+FD F++A L +F+ +T + W ++      A G+ +
Sbjct: 320 DSG-QCPEGYTCVKIGRNPDYGYTSFDTFSWAFLALFRLMTQDYWENLYQQTLRAAGKTY 378

Query: 381 PWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLK 435
             I+FV +I +GSF+++NL+L V++  + +E+ +A      QK  E QQ+ + LK
Sbjct: 379 -MIFFVVVIFLGSFYLINLILAVVAMAY-EEQNQANIEEAKQKELEFQQMLDRLK 431



 Score =  130 bits (328), Expect = 1e-29
 Identities = 100/324 (30%), Positives = 168/324 (51%), Gaps = 30/324 (9%)

Query: 492  RLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFL-VFLNTLTIASEHYNQPN 550
            R AH+      S YW ++     +KC   +  + F  L I + + LNTL +A EH+    
Sbjct: 705  RFAHKFLIWNCSPYWIKF-----KKCIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTE 759

Query: 551  WLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKI 610
                V    N     +F AEM+LK+ ++    YF   +N FD  +V   ++E  L + + 
Sbjct: 760  EFKNVLAIGNLVFTGIFAAEMVLKLIAMDPYEYFQVGWNIFDSLIVTLSLVELFLADVE- 818

Query: 611  MSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGM 670
                G+SVLR  RLLR+FK+ + W +L+ L+  + NSV ++ +L L+L + + IF+++GM
Sbjct: 819  ----GLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGM 874

Query: 671  QLFGGKFN------FDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSF 724
            QLFG  +        D+    R   ++F  S L VF++L GE W   M+D +   G    
Sbjct: 875  QLFGKSYKECVCKINDDCTLPRWHMNDFFHSFLIVFRVLCGE-WIETMWDCMEVAG---- 929

Query: 725  PGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASP 784
              M + +Y +++ I GN ++LN+FLA+ + + + +++LT+   EE+ +    ++A T   
Sbjct: 930  QAMCLIVYMMVMVI-GNLVVLNLFLALLLSSFS-SDNLTAI--EEDPDANNLQIAVTRIK 985

Query: 785  E----KKQELVEKPAVGESKEEKI 804
            +     KQ L E      SK+ KI
Sbjct: 986  KGINYVKQTLREFILKAFSKKPKI 1009



 Score =  107 bits (268), Expect = 1e-22
 Identities = 77/305 (25%), Positives = 139/305 (45%), Gaps = 79/305 (25%)

Query: 1212 VWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLI 1271
            ++++V   + +  + + I+LNT+ +AM+H+  +  FK  + I N++FTG+F  EM+LKLI
Sbjct: 726  IYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKNVLAIGNLVFTGIFAAEMVLKLI 785

Query: 1272 AFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEV 1331
            A  P  YF   WN+FD LIV  S++++ L++                             
Sbjct: 786  AMDPYEYFQVGWNIFDSLIVTLSLVELFLADVE--------------------------- 818

Query: 1332 NPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1391
                                 ++  R FR++R+ KL      +  L+     S  AL  +
Sbjct: 819  --------------------GLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNL 858

Query: 1392 ALLIVMLFFIYAVIGMQVFGK------IALNDTTEINR---NNNFQTFPQAVLLLFRCAT 1442
             L++ ++ FI+AV+GMQ+FGK        +ND   + R   N+ F +F    L++FR   
Sbjct: 859  TLVLAIIVFIFAVVGMQLFGKSYKECVCKINDDCTLPRWHMNDFFHSF----LIVFRVLC 914

Query: 1443 GEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAV 1502
            GE W + M  CM                     G +  +  ++   ++   +++NLF+A+
Sbjct: 915  GE-WIETMWDCM------------------EVAGQAMCLIVYMMVMVIGNLVVLNLFLAL 955

Query: 1503 IMDNF 1507
            ++ +F
Sbjct: 956  LLSSF 960



 Score =  102 bits (253), Expect = 5e-21
 Identities = 79/325 (24%), Positives = 148/325 (45%), Gaps = 42/325 (12%)

Query: 509  WNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASE--HYNQPNWLTEVQDTANKALLAL 566
            WN   R+ C   V+ + F   ++ ++ L++  +A E  +  +   +  + + A+K    +
Sbjct: 1168 WN--IRKTCYKIVEHSWFESFIVLMILLSSGALAFEDIYIERKKTIKIILEYADKIFTYI 1225

Query: 567  FTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLG-ISVLRCVRLL 625
            F  EMLLK  + G + YF + +   D F++    L T++  T   S LG I  LR +R L
Sbjct: 1226 FILEMLLKWIAYGYKTYFTNAWCWLD-FLIVDVSLVTLVANTLGYSDLGPIKSLRTLRAL 1284

Query: 626  RIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF-------- 677
            R  +    +  +  +V +L+ ++ SI ++LL+  +F +IFS++G+ LF GKF        
Sbjct: 1285 RPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYECINTTD 1344

Query: 678  ----------NFDEM------------QTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDG 715
                      N  E             +  +  FDN     L++ Q+ T + W  +MY  
Sbjct: 1345 GSRFPASQVPNRSECFALMNVSQNVRWKNLKVNFDNVGLGYLSLLQVATFKGWTIIMYAA 1404

Query: 716  IMAYGGPSFP----GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQK--EE 769
            + +      P     + + IYF++  I G++  LN+F+ + +DN    +     Q     
Sbjct: 1405 VDSVNVDKQPKYEYSLYMYIYFVVFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMT 1464

Query: 770  EEEKERKKLARTASPEKKQELVEKP 794
            EE+K+     +    +K Q+ + +P
Sbjct: 1465 EEQKKYYNAMKKLGSKKPQKPIPRP 1489



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 94/407 (23%), Positives = 177/407 (43%), Gaps = 70/407 (17%)

Query: 830  ENEDKSPYPNPETTGEEDEEEP----EMPVGPRPRPLSELHL----KEKAVPMPEASAFF 881
            + +D    P P +  E  ++ P    ++P G    PL +L      K+  + + +    F
Sbjct: 39   KKDDDEEAPKPSSDLEAGKQLPFIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKTIF 98

Query: 882  IFSSN---------NRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHI 932
             F++          +  R    +I+  ++F+ LI+  IL + I +   +P   T      
Sbjct: 99   RFNATPALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMNNPPDWTK----- 153

Query: 933  LFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAIN 992
                +  FT I+T E  +K+ A G  + + +F R+ +N LD +V+  + ++  +    + 
Sbjct: 154  --NVEYTFTGIYTFESLVKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVN---LG 208

Query: 993  VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFK 1052
             V  LR  RVLR L+ I+   GLK +V  +  +++ + +++I+T     +FA IG+QLF 
Sbjct: 209  NVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFM 268

Query: 1053 GKL-YTCSDSSKQTEAECKG------------NYITYKDGEVDHPIIQ--------PRSW 1091
            G L + C  +S +     +              Y  Y +G  D  +          P  +
Sbjct: 269  GNLKHKCFRNSLENNETLESIMNTLESEEDFRKYFYYLEGSKDALLCGFSTDSGQCPEGY 328

Query: 1092 ENSKF---------DFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEI 1142
               K           FD    A +ALF + T + W  L  +++ +     G  Y      
Sbjct: 329  TCVKIGRNPDYGYTSFDTFSWAFLALFRLMTQDYWENLYQQTLRA----AGKTY------ 378

Query: 1143 SIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE---QEYKNCELDKNQ 1186
             IFF++ I + +F+++N+ +  V + ++EQ +   +E K  EL+  Q
Sbjct: 379  MIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKELEFQQ 425



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 95/353 (26%), Positives = 151/353 (42%), Gaps = 48/353 (13%)

Query: 79   TQRKRQQYGKPKKQGSTTATRP-PRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFAN 137
            T+ +++ Y   KK GS    +P PR        N I+     +V  + F+I I++ I  N
Sbjct: 1464 TEEQKKYYNAMKKLGSKKPQKPIPRP------GNKIQGCIFDLVTNQAFDISIMVLICLN 1517

Query: 138  CVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNL 197
             V + +     E  S      L  +  +F+I+FT E  LK+I+       + Y   GWN+
Sbjct: 1518 MVTMMVE---KEGQSQHMTEVLYWINVVFIILFTGECVLKLISLR-----HYYFTVGWNI 1569

Query: 198  LDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVV 257
             DF++V++ +    L     AD           F V  +R  R+ R LRLV G   ++ +
Sbjct: 1570 FDFVVVIISIVGMFL-----ADLIETYFVSPTLFRV--IRLARIGRILRLVKGAKGIRTL 1622

Query: 258  LNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCA 317
            L +++ ++  L +I LL+  V+ IYAI G+  F          ++GI D+          
Sbjct: 1623 LFALMMSLPALFNIGLLLFLVMFIYAIFGMSNF-----AYVKKEDGINDM--------FN 1669

Query: 318  LET-GHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV 376
             ET G+   C        GWDG    I N          V    ++EG        N +V
Sbjct: 1670 FETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPKKVHPGSSVEGDCG-----NPSV 1724

Query: 377  GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFS---KEREKAKARGDFQKLRE 426
            G      YFV+ III    V+N+ + V+   FS   +E  +  +  DF+   E
Sbjct: 1725 G----IFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDFEMFYE 1773



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 75/299 (25%), Positives = 132/299 (44%), Gaps = 60/299 (20%)

Query: 115 RACISIVEWKPF-EIIILLTIFANCVALAI-YIPFPEDDSNATNSNLERVEYLFLIIFTV 172
           + CI  +   PF ++ I + I  N + +A+ + P  E+  N     L     +F  IF  
Sbjct: 723 KKCIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKNV----LAIGNLVFTGIFAA 778

Query: 173 EAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFD 232
           E  LK+IA      P  Y + GWN+ D +IV + L    L                    
Sbjct: 779 EMVLKLIA----MDPYEYFQVGWNIFDSLIVTLSLVELFLADVE---------------G 819

Query: 233 VKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMG 292
           +  LR+FR+LR  +L    P+L +++  I  ++  L ++ L++  ++ I+A++G++LF G
Sbjct: 820 LSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-G 878

Query: 293 KMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFA 352
           K +K C            DD   C L               P W        + ++F  +
Sbjct: 879 KSYKECV-------CKINDD---CTL---------------PRW--------HMNDFFHS 905

Query: 353 MLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKE 411
            L VF+ +  E W + ++   +  G+    I ++ +++IG+  VLNL L +L   FS +
Sbjct: 906 FLIVFRVLCGE-WIETMWDCMEVAGQAMCLIVYMMVMVIGNLVVLNLFLALLLSSFSSD 963



 Score = 68.2 bits (165), Expect = 9e-11
 Identities = 47/169 (27%), Positives = 89/169 (52%), Gaps = 8/169 (4%)

Query: 888  RFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIE 947
            +F+   + IV D      I   I+L+++ +A E       F+N +L   ++VFT IF  E
Sbjct: 721  KFKKCIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKN-VLAIGNLVFTGIFAAE 779

Query: 948  IALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLR 1007
            + LK+ A   +     + +  +NI D L+V++SL+   +    +  + +LR  R+LR  +
Sbjct: 780  MVLKLIAMDPY----EYFQVGWNIFDSLIVTLSLVELFLAD--VEGLSVLRSFRLLRVFK 833

Query: 1008 AINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLY 1056
                   L  +++ +  ++  +GN+ +V  ++ F+FA +G+QLF GK Y
Sbjct: 834  LAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-GKSY 881



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 80/383 (20%), Positives = 148/383 (38%), Gaps = 75/383 (19%)

Query: 524 NVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKM----YSLG 579
           ++F  L++  +  N + +     N P+W   V+ T       ++T E L+K+    + +G
Sbjct: 126 SLFSMLIMCTILTNCIFMTMN--NPPDWTKNVEYT----FTGIYTFESLVKILARGFCVG 179

Query: 580 LQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSN 639
              +    +N  D  V+    L      T+ ++   +S LR  R+LR  K       L  
Sbjct: 180 EFTFLRDPWNWLDFVVIVFAYL------TEFVNLGNVSALRTFRVLRALKTISVIPGLKT 233

Query: 640 LVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF----------NFDEMQTRRSTF 689
           +V +L+ SV+ ++ +++L    + +F+L+G+QLF G            N + +++  +T 
Sbjct: 234 IVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRNSLENNETLESIMNTL 293

Query: 690 DN-------------FPQSLLTVFQILTG---EDWNSVMYDGIMAYGGPSF--------- 724
           ++                +LL  F   +G   E +  V       YG  SF         
Sbjct: 294 ESEEDFRKYFYYLEGSKDALLCGFSTDSGQCPEGYTCVKIGRNPDYGYTSFDTFSWAFLA 353

Query: 725 --------------------PGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764
                                G    I+F+++   G++ L+N+ LA+        E    
Sbjct: 354 LFRLMTQDYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVA---MAYEEQNQ 410

Query: 765 AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPAT-KINM 823
           A  EE ++KE +        +K+QE  E  A   ++   I    I    ES   T K++ 
Sbjct: 411 ANIEEAKQKELEFQQMLDRLKKEQEEAEAIAAAAAEYTSIRRSRIMGLSESSSETSKLSS 470

Query: 824 DDLQPNENEDKSPYPNPETTGEE 846
              +   N  K       ++GEE
Sbjct: 471 KSAKERRNRRKKKNQKKLSSGEE 493



 Score = 48.5 bits (114), Expect = 7e-05
 Identities = 60/313 (19%), Positives = 111/313 (35%), Gaps = 137/313 (43%)

Query: 1258 FTGLFTVEMILKLIAFKPKGY-------FSDPWNVFDFLIVIGSIIDVILSETNHYFCDA 1310
            FTG++T E ++K++A   +G+         DPWN  DF++++ + +   ++  N      
Sbjct: 159  FTGIYTFESLVKILA---RGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVNLGN------ 209

Query: 1311 WNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSR 1370
                                                      ++  R FRV+R +K +S 
Sbjct: 210  ------------------------------------------VSALRTFRVLRALKTISV 227

Query: 1371 GEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF----------GKIALNDTTE 1420
              G++T++   I+S + L  V +L V    ++A+IG+Q+F            +  N+T E
Sbjct: 228  IPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRNSLENNETLE 287

Query: 1421 ---------------------------------------------INRN-----NNFQTF 1430
                                                         I RN      +F TF
Sbjct: 288  SIMNTLESEEDFRKYFYYLEGSKDALLCGFSTDSGQCPEGYTCVKIGRNPDYGYTSFDTF 347

Query: 1431 PQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYML 1490
              A L LFR  T + W+++    +                     G ++ +F+ +  + L
Sbjct: 348  SWAFLALFRLMTQDYWENLYQQTL------------------RAAGKTYMIFFVVVIF-L 388

Query: 1491 CAFLIINLFVAVI 1503
             +F +INL +AV+
Sbjct: 389  GSFYLINLILAVV 401


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,043,801
Number of Sequences: 37866
Number of extensions: 4004717
Number of successful extensions: 26259
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 122
Number of HSP's successfully gapped in prelim test: 265
Number of HSP's that attempted gapping in prelim test: 19388
Number of HSP's gapped (non-prelim): 3048
length of query: 2166
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2048
effective length of database: 13,779,330
effective search space: 28220067840
effective search space used: 28220067840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.