BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|193788728 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 3 [Homo sapiens] (2179 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|193788728 calcium channel, voltage-dependent, L type, alpha 1... 4368 0.0 gi|193788528 calcium channel, voltage-dependent, L type, alpha 1... 4308 0.0 gi|193788530 calcium channel, voltage-dependent, L type, alpha 1... 4292 0.0 gi|193794828 calcium channel, voltage-dependent, L type, alpha 1... 4288 0.0 gi|193788532 calcium channel, voltage-dependent, L type, alpha 1... 4280 0.0 gi|193794832 calcium channel, voltage-dependent, L type, alpha 1... 4275 0.0 gi|193788534 calcium channel, voltage-dependent, L type, alpha 1... 4264 0.0 gi|120433602 calcium channel, voltage-dependent, L type, alpha 1... 4256 0.0 gi|193788526 calcium channel, voltage-dependent, L type, alpha 1... 4244 0.0 gi|193788732 calcium channel, voltage-dependent, L type, alpha 1... 4241 0.0 gi|193788542 calcium channel, voltage-dependent, L type, alpha 1... 4240 0.0 gi|193788540 calcium channel, voltage-dependent, L type, alpha 1... 4236 0.0 gi|193788724 calcium channel, voltage-dependent, L type, alpha 1... 4229 0.0 gi|193788544 calcium channel, voltage-dependent, L type, alpha 1... 4224 0.0 gi|193788730 calcium channel, voltage-dependent, L type, alpha 1... 4222 0.0 gi|193788536 calcium channel, voltage-dependent, L type, alpha 1... 4222 0.0 gi|193788538 calcium channel, voltage-dependent, L type, alpha 1... 4219 0.0 gi|193788720 calcium channel, voltage-dependent, L type, alpha 1... 4212 0.0 gi|193788548 calcium channel, voltage-dependent, L type, alpha 1... 4212 0.0 gi|193794830 calcium channel, voltage-dependent, L type, alpha 1... 4197 0.0 gi|192807300 calcium channel, voltage-dependent, L type, alpha 1... 2731 0.0 gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D ... 2731 0.0 gi|192807298 calcium channel, voltage-dependent, L type, alpha 1... 2726 0.0 gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F... 2274 0.0 gi|110349767 calcium channel, voltage-dependent, L type, alpha 1... 2273 0.0 gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s... 765 0.0 gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 758 0.0 gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s... 757 0.0 gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E... 734 0.0 gi|111378393 sodium channel, voltage-gated, type VII, alpha [Hom... 400 e-111 >gi|193788728 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 3 [Homo sapiens] Length = 2179 Score = 4368 bits (11329), Expect = 0.0 Identities = 2179/2179 (100%), Positives = 2179/2179 (100%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE Sbjct: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2161 RGRPSEEELQDSRVYVSSL 2179 >gi|193788528 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 8 [Homo sapiens] Length = 2157 Score = 4308 bits (11174), Expect = 0.0 Identities = 2157/2179 (98%), Positives = 2157/2179 (98%), Gaps = 22/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM----- 1315 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE Sbjct: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1598 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1599 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1658 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1659 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1718 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1719 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1778 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1779 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1838 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1839 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1898 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1899 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1958 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1959 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2018 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2019 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2078 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2079 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2138 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2139 RGRPSEEELQDSRVYVSSL 2157 >gi|193788530 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 9 [Homo sapiens] Length = 2157 Score = 4292 bits (11132), Expect = 0.0 Identities = 2150/2179 (98%), Positives = 2152/2179 (98%), Gaps = 22/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM----- 1315 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE Sbjct: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1598 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1599 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1658 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1659 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1718 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1719 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1778 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1779 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1838 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1839 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1898 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1899 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1958 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1959 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2018 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2019 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2078 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2079 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2138 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2139 RGRPSEEELQDSRVYVSSL 2157 >gi|193794828 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 7 [Homo sapiens] Length = 2157 Score = 4288 bits (11120), Expect = 0.0 Identities = 2145/2179 (98%), Positives = 2150/2179 (98%), Gaps = 22/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSM----- 1315 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE Sbjct: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1598 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1599 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1658 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1659 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1718 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1719 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1778 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1779 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1838 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1839 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1898 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1899 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1958 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1959 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2018 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2019 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2078 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2079 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2138 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2139 RGRPSEEELQDSRVYVSSL 2157 >gi|193788532 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 11 [Homo sapiens] Length = 2146 Score = 4280 bits (11100), Expect = 0.0 Identities = 2146/2179 (98%), Positives = 2146/2179 (98%), Gaps = 33/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN---------------- 1304 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1305 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1347 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1348 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1407 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1408 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1467 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1468 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1527 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE Sbjct: 1528 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1587 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1588 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1647 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1648 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1707 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1708 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1767 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1768 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1827 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1828 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1887 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1888 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1947 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1948 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2007 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2008 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2067 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2068 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2127 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2128 RGRPSEEELQDSRVYVSSL 2146 >gi|193794832 calcium channel, voltage-dependent, L type, alpha 1C subunit isoforom 13 [Homo sapiens] Length = 2144 Score = 4275 bits (11088), Expect = 0.0 Identities = 2144/2179 (98%), Positives = 2144/2179 (98%), Gaps = 35/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITE Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITE------------------ 1302 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1303 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1345 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1346 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1405 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1406 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1465 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1466 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1525 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE Sbjct: 1526 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1585 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1586 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1645 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1646 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1705 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1706 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1765 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1766 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1825 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1826 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1885 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1886 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1945 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1946 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2005 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2006 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2065 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2066 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2125 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2126 RGRPSEEELQDSRVYVSSL 2144 >gi|193788534 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 12 [Homo sapiens] Length = 2146 Score = 4264 bits (11058), Expect = 0.0 Identities = 2139/2179 (98%), Positives = 2141/2179 (98%), Gaps = 33/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN---------------- 1304 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1305 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1347 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1348 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1407 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1408 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1467 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1468 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1527 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE Sbjct: 1528 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1587 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1588 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1647 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1648 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1707 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1708 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1767 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1768 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1827 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1828 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1887 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1888 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1947 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1948 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2007 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2008 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2067 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2068 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2127 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2128 RGRPSEEELQDSRVYVSSL 2146 >gi|120433602 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 18 [Homo sapiens] Length = 2138 Score = 4256 bits (11039), Expect = 0.0 Identities = 2138/2179 (98%), Positives = 2138/2179 (98%), Gaps = 41/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM----- 1315 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLE Sbjct: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLE 1579 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1580 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1640 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1699 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1700 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1759 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1760 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1819 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1820 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1879 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1880 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1939 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1940 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 1999 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2000 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2059 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2060 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2119 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2120 RGRPSEEELQDSRVYVSSL 2138 >gi|193788526 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 6 [Homo sapiens] Length = 2158 Score = 4244 bits (11008), Expect = 0.0 Identities = 2138/2199 (97%), Positives = 2138/2199 (97%), Gaps = 61/2199 (2%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA----------- 949 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 950 ---------LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAI 1300 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAI Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAI 1320 Query: 1301 TEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVK 1360 TEVNPAEHTQCSPSM NAEENSRISITFFRLFRVMRLVK Sbjct: 1321 TEVNPAEHTQCSPSM----------------------NAEENSRISITFFRLFRVMRLVK 1358 Query: 1361 LLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNN 1420 LLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNN Sbjct: 1359 LLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNN 1418 Query: 1421 FQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFIS 1480 FQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFIS Sbjct: 1419 FQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFIS 1478 Query: 1481 FYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVV 1540 FYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVV Sbjct: 1479 FYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVV 1538 Query: 1541 TLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGP 1600 TLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE Sbjct: 1539 TLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE--- 1595 Query: 1601 SPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFY 1660 GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFY Sbjct: 1596 ----------------GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFY 1639 Query: 1661 ATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEEL 1720 ATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEEL Sbjct: 1640 ATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEEL 1699 Query: 1721 DKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGD 1780 DKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGD Sbjct: 1700 DKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGD 1759 Query: 1781 TESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLS 1840 TESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLS Sbjct: 1760 TESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLS 1819 Query: 1841 PAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEML 1900 PAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEML Sbjct: 1820 PAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEML 1879 Query: 1901 SYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTV 1960 SYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTV Sbjct: 1880 SYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTV 1939 Query: 1961 LPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVES 2020 LPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVES Sbjct: 1940 LPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVES 1999 Query: 2021 SEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEA 2080 SEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEA Sbjct: 2000 SEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEA 2059 Query: 2081 VLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVN 2140 VLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVN Sbjct: 2060 VLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVN 2119 Query: 2141 CRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2179 CRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2120 CRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2158 >gi|193788732 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 5 [Homo sapiens] Length = 2166 Score = 4241 bits (11000), Expect = 0.0 Identities = 2138/2207 (96%), Positives = 2138/2207 (96%), Gaps = 69/2207 (3%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292 LFTVEMILKLIAFKPK HYFCDAWNTFDALIVV Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 Query: 1293 GSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRL 1352 GSIVDIAITEVNPAEHTQCSPSM NAEENSRISITFFRL Sbjct: 1321 GSIVDIAITEVNPAEHTQCSPSM----------------------NAEENSRISITFFRL 1358 Query: 1353 FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT 1412 FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT Sbjct: 1359 FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT 1418 Query: 1413 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS 1472 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS Sbjct: 1419 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS 1478 Query: 1473 FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG 1532 FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG Sbjct: 1479 FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG 1538 Query: 1533 RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL 1592 RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL Sbjct: 1539 RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL 1598 Query: 1593 RIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDD 1652 RIKTE GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDD Sbjct: 1599 RIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDD 1639 Query: 1653 EVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISG 1712 EVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISG Sbjct: 1640 EVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISG 1699 Query: 1713 DLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHIN 1772 DLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHIN Sbjct: 1700 DLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHIN 1759 Query: 1773 KAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTV 1832 KAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTV Sbjct: 1760 KAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTV 1819 Query: 1833 EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEP 1892 EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEP Sbjct: 1820 EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEP 1879 Query: 1893 SLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRG 1952 SLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRG Sbjct: 1880 SLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRG 1939 Query: 1953 GDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPT 2012 GDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPT Sbjct: 1940 GDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPT 1999 Query: 2013 LRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHG 2072 LRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHG Sbjct: 2000 LRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHG 2059 Query: 2073 SASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPN 2132 SASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPN Sbjct: 2060 SASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPN 2119 Query: 2133 GALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2179 GALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2120 GALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2166 >gi|193788542 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 17 [Homo sapiens] Length = 2138 Score = 4240 bits (10997), Expect = 0.0 Identities = 2131/2179 (97%), Positives = 2133/2179 (97%), Gaps = 41/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM----- 1315 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLE Sbjct: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLE 1579 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1580 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1640 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1699 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1700 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1759 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1760 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1819 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1820 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1879 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1880 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1939 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1940 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 1999 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2000 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2059 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2060 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2119 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2120 RGRPSEEELQDSRVYVSSL 2138 >gi|193788540 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 16 [Homo sapiens] Length = 2138 Score = 4236 bits (10985), Expect = 0.0 Identities = 2126/2179 (97%), Positives = 2131/2179 (97%), Gaps = 41/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSM----- 1315 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLE Sbjct: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLE 1579 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1580 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1640 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1699 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1700 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1759 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1760 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1819 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1820 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1879 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1880 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1939 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1940 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 1999 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2000 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2059 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2060 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2119 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2120 RGRPSEEELQDSRVYVSSL 2138 >gi|193788724 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 2 [Homo sapiens] Length = 2186 Score = 4229 bits (10969), Expect = 0.0 Identities = 2138/2227 (96%), Positives = 2138/2227 (96%), Gaps = 89/2227 (3%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA----------- 949 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 950 ---------LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------ 1276 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1320 Query: 1277 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPV 1332 HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM Sbjct: 1321 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM----------------- 1363 Query: 1333 ADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML 1392 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML Sbjct: 1364 -----NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML 1418 Query: 1393 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK 1452 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK Sbjct: 1419 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK 1478 Query: 1453 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG 1512 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG Sbjct: 1479 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG 1538 Query: 1513 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL 1572 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL Sbjct: 1539 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL 1598 Query: 1573 NSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKK 1632 NSDGTVMFNATLFALVRTALRIKTE GNLEQANEELRAIIKK Sbjct: 1599 NSDGTVMFNATLFALVRTALRIKTE-------------------GNLEQANEELRAIIKK 1639 Query: 1633 IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL 1692 IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL Sbjct: 1640 IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL 1699 Query: 1693 QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQ 1752 QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQ Sbjct: 1700 QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQ 1759 Query: 1753 SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN 1812 SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN Sbjct: 1760 SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN 1819 Query: 1813 NTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEET 1872 NTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEET Sbjct: 1820 NTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEET 1879 Query: 1873 SQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSA 1932 SQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSA Sbjct: 1880 SQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSA 1939 Query: 1933 SLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRP 1992 SLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRP Sbjct: 1940 SLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRP 1999 Query: 1993 FATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRV 2052 FATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRV Sbjct: 2000 FATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRV 2059 Query: 2053 RPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTI 2112 RPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTI Sbjct: 2060 RPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTI 2119 Query: 2113 EEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDS 2172 EEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDS Sbjct: 2120 EEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDS 2179 Query: 2173 RVYVSSL 2179 RVYVSSL Sbjct: 2180 RVYVSSL 2186 >gi|193788544 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 19 [Homo sapiens] Length = 2135 Score = 4224 bits (10954), Expect = 0.0 Identities = 2123/2179 (97%), Positives = 2128/2179 (97%), Gaps = 44/2179 (2%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIA AEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIA---AEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 357 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 358 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 417 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 418 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 477 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 478 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 537 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 538 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 597 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 598 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 657 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 658 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 717 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 718 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 777 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 778 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 837 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 838 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 897 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH Sbjct: 898 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 957 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 958 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1017 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1018 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1077 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1078 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1137 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1138 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1197 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1198 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1257 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSM Sbjct: 1258 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSM----- 1312 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1313 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1355 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1356 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1415 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1416 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1475 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1476 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1535 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLE Sbjct: 1536 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLE 1576 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1577 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1636 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1637 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1696 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1697 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1756 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1757 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1816 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1817 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1876 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1877 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1936 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1937 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 1996 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 1997 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2056 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2057 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2116 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2117 RGRPSEEELQDSRVYVSSL 2135 >gi|193788730 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 4 [Homo sapiens] Length = 2173 Score = 4222 bits (10951), Expect = 0.0 Identities = 2131/2214 (96%), Positives = 2133/2214 (96%), Gaps = 76/2214 (3%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM----- 1315 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLE Sbjct: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLE 1579 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1580 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1640 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1699 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1700 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1759 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSN----- 1855 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSN Sbjct: 1760 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRERHV 1819 Query: 1856 ------------------------------RCHSRESQAAMAGQEETSQDETYEVKMNHD 1885 RCHSRESQAAMAGQEETSQDETYEVKMNHD Sbjct: 1820 PMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETYEVKMNHD 1879 Query: 1886 TEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECL 1945 TEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECL Sbjct: 1880 TEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECL 1939 Query: 1946 KRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGW 2005 KRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGW Sbjct: 1940 KRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGW 1999 Query: 2006 PPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGA 2065 PPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGA Sbjct: 2000 PPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGA 2059 Query: 2066 PGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSG 2125 PGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSG Sbjct: 2060 PGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSG 2119 Query: 2126 GAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2179 GAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2120 GAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2173 >gi|193788536 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 14 [Homo sapiens] Length = 2138 Score = 4222 bits (10951), Expect = 0.0 Identities = 2121/2179 (97%), Positives = 2129/2179 (97%), Gaps = 41/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYW+ DA+G + PW+YFV+L+I GSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM----- 1315 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLE Sbjct: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLE 1579 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1580 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1640 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1699 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1700 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1759 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1760 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1819 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1820 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1879 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1880 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1939 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1940 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 1999 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2000 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2059 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2060 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2119 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2120 RGRPSEEELQDSRVYVSSL 2138 >gi|193788538 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 15 [Homo sapiens] Length = 2138 Score = 4219 bits (10943), Expect = 0.0 Identities = 2119/2179 (97%), Positives = 2126/2179 (97%), Gaps = 41/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSM----- 1315 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLE Sbjct: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLE 1579 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1580 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1640 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1699 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1700 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1759 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1760 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1819 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1820 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1879 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1880 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1939 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1940 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 1999 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2000 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2059 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2060 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2119 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2120 RGRPSEEELQDSRVYVSSL 2138 >gi|193788720 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 1 [Homo sapiens] Length = 2221 Score = 4212 bits (10923), Expect = 0.0 Identities = 2138/2262 (94%), Positives = 2138/2262 (94%), Gaps = 124/2262 (5%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA----------- 949 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 950 ---------LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------ 1276 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1320 Query: 1277 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPV 1332 HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM Sbjct: 1321 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM----------------- 1363 Query: 1333 ADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML 1392 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML Sbjct: 1364 -----NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML 1418 Query: 1393 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK 1452 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK Sbjct: 1419 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK 1478 Query: 1453 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG 1512 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG Sbjct: 1479 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG 1538 Query: 1513 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL 1572 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL Sbjct: 1539 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL 1598 Query: 1573 NSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKK 1632 NSDGTVMFNATLFALVRTALRIKTE GNLEQANEELRAIIKK Sbjct: 1599 NSDGTVMFNATLFALVRTALRIKTE-------------------GNLEQANEELRAIIKK 1639 Query: 1633 IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL 1692 IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL Sbjct: 1640 IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL 1699 Query: 1693 QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQ 1752 QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQ Sbjct: 1700 QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQ 1759 Query: 1753 SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN 1812 SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN Sbjct: 1760 SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN 1819 Query: 1813 NTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSN----------------- 1855 NTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSN Sbjct: 1820 NTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRERHVPMCEDLELRRDS 1879 Query: 1856 ------------------RCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLST 1897 RCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLST Sbjct: 1880 GSAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLST 1939 Query: 1898 EMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQ 1957 EMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQ Sbjct: 1940 EMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQ 1999 Query: 1958 KTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEG 2017 KTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEG Sbjct: 2000 KTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEG 2059 Query: 2018 VESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSL 2077 VESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSL Sbjct: 2060 VESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSL 2119 Query: 2078 VEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLP 2137 VEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLP Sbjct: 2120 VEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLP 2179 Query: 2138 FVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2179 FVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2180 FVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2221 >gi|193788548 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 20 [Homo sapiens] Length = 2127 Score = 4212 bits (10923), Expect = 0.0 Identities = 2120/2179 (97%), Positives = 2122/2179 (97%), Gaps = 52/2179 (2%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN---------------- 1304 Query: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1305 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1347 Query: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1348 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1407 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1408 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1467 Query: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1468 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1527 Query: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLE Sbjct: 1528 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLE 1568 Query: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1569 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1628 Query: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1629 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1688 Query: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1689 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1748 Query: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1749 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1808 Query: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1809 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1868 Query: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1869 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1928 Query: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1929 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 1988 Query: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 1989 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2048 Query: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2049 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2108 Query: 2161 RGRPSEEELQDSRVYVSSL 2179 RGRPSEEELQDSRVYVSSL Sbjct: 2109 RGRPSEEELQDSRVYVSSL 2127 >gi|193794830 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 10 [Homo sapiens] Length = 2155 Score = 4197 bits (10884), Expect = 0.0 Identities = 2120/2207 (96%), Positives = 2122/2207 (96%), Gaps = 80/2207 (3%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPK----------------------------HYFCDAWNTFDALIVV 1292 LFTVEMILKLIAFKPK HYFCDAWNTFDALIVV Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 Query: 1293 GSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRL 1352 GSIVDIAITEVN NAEENSRISITFFRL Sbjct: 1321 GSIVDIAITEVN---------------------------------NAEENSRISITFFRL 1347 Query: 1353 FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT 1412 FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT Sbjct: 1348 FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT 1407 Query: 1413 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS 1472 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS Sbjct: 1408 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS 1467 Query: 1473 FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG 1532 FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG Sbjct: 1468 FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG 1527 Query: 1533 RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL 1592 RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL Sbjct: 1528 RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL 1587 Query: 1593 RIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDD 1652 RIKTE GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDD Sbjct: 1588 RIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDD 1628 Query: 1653 EVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISG 1712 EVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISG Sbjct: 1629 EVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISG 1688 Query: 1713 DLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHIN 1772 DLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHIN Sbjct: 1689 DLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHIN 1748 Query: 1773 KAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTV 1832 KAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTV Sbjct: 1749 KAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTV 1808 Query: 1833 EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEP 1892 EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEP Sbjct: 1809 EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEP 1868 Query: 1893 SLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRG 1952 SLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRG Sbjct: 1869 SLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRG 1928 Query: 1953 GDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPT 2012 GDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPT Sbjct: 1929 GDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPT 1988 Query: 2013 LRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHG 2072 LRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHG Sbjct: 1989 LRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHG 2048 Query: 2073 SASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPN 2132 SASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPN Sbjct: 2049 SASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPN 2108 Query: 2133 GALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2179 GALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2109 GALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 >gi|192807300 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform b [Homo sapiens] Length = 2161 Score = 2731 bits (7078), Expect = 0.0 Identities = 1457/2194 (66%), Positives = 1668/2194 (76%), Gaps = 147/2194 (6%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYW+NDA+G + PW+YFV+L+I GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN--CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524 PTSETESVNTENV+G EGEN C L ISKSK SR WRRWNRF RR+CRAAVKS Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSV 523 Query: 525 VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584 FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LLALFT EML+KMYSLGLQAYF Sbjct: 524 TFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYF 583 Query: 585 VSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASL 644 VSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRLLRIFK+TR+W SLSNLVASL Sbjct: 584 VSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASL 643 Query: 645 LNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILT 704 LNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT+RSTFDNFPQ+LLTVFQILT Sbjct: 644 LNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILT 703 Query: 705 GEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764 GEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYILLNVFLAIAVDNLADAESL + Sbjct: 704 GEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNT 763 Query: 765 AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMD 824 AQKEE EEKERKK+AR S E K+ KP V + K+ +D Sbjct: 764 AQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD---------------NKVTID 806 Query: 825 DLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASA 879 D + E+EDK PYP E EE+E+EPE+P GPRPR +SEL++KEK P+PE SA Sbjct: 807 DYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSA 865 Query: 880 FFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIV 939 FFI S N R+ CH+++N IFTNLIL FI+LSS +LAAEDP++ SFRN IL YFD Sbjct: 866 FFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYA 925 Query: 940 FTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRV 999 FT IFT+EI LKMT +GAFLHKG+FCRNYFN+LD+LVV VSL+SFGIQSSAI+VVKILRV Sbjct: 926 FTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRV 985 Query: 1000 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS 1059 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Y C+ Sbjct: 986 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCT 1045 Query: 1060 DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE 1119 D +K EC+G +I YKDG+VD P+++ R W+NS F+FDNVL+AMMALFTVSTFEGWP Sbjct: 1046 DEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPA 1105 Query: 1120 LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN 1179 LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMNIFVGFVIVTFQEQGE+EYKN Sbjct: 1106 LLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKN 1165 Query: 1180 CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239 CELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ FEY+MFVLI+LNT+CLAMQ Sbjct: 1166 CELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQ 1225 Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIA 1299 HY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPK YF DAWNTFD+LIV+GSI+D+A Sbjct: 1226 HYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVA 1285 Query: 1300 ITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLV 1359 ++E +P E + V TA P N+EE++RISITFFRLFRVMRLV Sbjct: 1286 LSEADPTESEN-------------VPVPTATP-----GNSEESNRISITFFRLFRVMRLV 1327 Query: 1360 KLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNN 1419 KLLSRGEGIRTLLWTFIKSFQALPYVALLI MLFFIYAVIGMQ+FGK+A+ D +INRNN Sbjct: 1328 KLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNN 1387 Query: 1420 NFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFI 1479 NFQTFPQAVLLLFRCATGEAWQ+IMLAC+PGK C PES+ + E CGS+FA+ YFI Sbjct: 1388 NFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGE--EYTCGSNFAIVYFI 1445 Query: 1480 SFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDV 1539 SFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDPEAKGRIKHLDV Sbjct: 1446 SFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDV 1505 Query: 1540 VTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEG 1599 VTLLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTVMFNATLFALVRTAL+IKTE Sbjct: 1506 VTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTE-- 1563 Query: 1600 PSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKF 1659 GNLEQANEELRA+IKKIWK+TSMKLLDQVVPPAGDDEVTVGKF Sbjct: 1564 -----------------GNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKF 1606 Query: 1660 YATFLIQEYFRKFKKRKEQGLVGK-PSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEE 1718 YATFLIQ+YFRKFKKRKEQGLVGK P++ ++LQAGLRTLHDIGPEIRRAIS DL +E Sbjct: 1607 YATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDE 1666 Query: 1719 ELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG-SS 1777 E EDD+F+R G L GNHV++ SD R + QT TT RPLH+ + Sbjct: 1667 ------PEETKREEEDDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPP 1720 Query: 1778 QGDTESPSHEKLVDST-FTPSSYSS------TGSNANINNANNTALGRLPRPA----GYP 1826 DTE P +S +++S T +NAN+NNAN + RP+ + Sbjct: 1721 ASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHV 1780 Query: 1827 STVSTVEGHGPPLSPAIR--VQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNH 1884 S H P R V+ + + R S + Q +E+ + Sbjct: 1781 SENGHHSSHKHDREPQRRSSVKRTRYYETYIRSDSGDEQLPTICREDPEIHGYF-----R 1835 Query: 1885 DTEACSEPSLLSTEMLSYQDD-----------------------------ENRQLTLPEE 1915 D E S+E Y+DD + Q L ++ Sbjct: 1836 DPHCLGEQEYFSSEE-CYEDDSSPTWSRQNYGYYSRYPGRNIDSERPRGYHHPQGFLEDD 1894 Query: 1916 DK---RDIRQSPKRGFL-RSASLGRRASFHLECLKRQKDR-----GGDISQKTVLPLHLV 1966 D D R+SP+R L + + RR+SF+ ECL+RQ + +T LPLHL+ Sbjct: 1895 DSPVCYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLM 1954 Query: 1967 HHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNS 2026 Q +AVAGL + +SP+ R +ATPPATP R W P P +++E E+ +++N Sbjct: 1955 QQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQSEALDQVNG 2014 Query: 2027 SFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEG 2086 S PS+H SW P + R P SL VPS SA SLVEAVLISEG Sbjct: 2015 SLPSLHRSSWYTDEP----DISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEG 2070 Query: 2087 LGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAG- 2145 LG++A+DPKF+ T E+ADACD+TI+EMESAA +L+G NG + P + +D Sbjct: 2071 LGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLNGNVRPRANGDVGPLSHRQDYEL 2130 Query: 2146 QDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2179 QD G D R EE+L D + +++L Sbjct: 2131 QDFGPGYSDEEPDPGR---DEEDLADEMICITTL 2161 >gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform a [Homo sapiens] Length = 2181 Score = 2731 bits (7078), Expect = 0.0 Identities = 1461/2214 (65%), Positives = 1672/2214 (75%), Gaps = 167/2214 (7%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYWVNDA+G +WPW+YFV+LII+GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN---CGA-------------------RLAHRISKSKFSR 504 PTSETESVNTENV+G EGEN CG+ R ISKSK SR Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLWCWWRRRGAAKAGPSGCRRWGQAISKSKLSR 523 Query: 505 YWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALL 564 WRRWNRF RR+CRAAVKS FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LL Sbjct: 524 RWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLL 583 Query: 565 ALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRL 624 ALFT EML+KMYSLGLQAYFVSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRL Sbjct: 584 ALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRL 643 Query: 625 LRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQT 684 LRIFK+TR+W SLSNLVASLLNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT Sbjct: 644 LRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQT 703 Query: 685 RRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYIL 744 +RSTFDNFPQ+LLTVFQILTGEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYIL Sbjct: 704 KRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYIL 763 Query: 745 LNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKI 804 LNVFLAIAVDNLADAESL +AQKEE EEKERKK+AR S E K+ KP V + Sbjct: 764 LNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD- 820 Query: 805 ELKSITADGESPPATKINMDDLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRP 859 K+ +DD + E+EDK PYP E EE+E+EPE+P GPRP Sbjct: 821 --------------NKVTIDDYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRP 865 Query: 860 RPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAA 919 R +SEL++KEK P+PE SAFFI S N R+ CH+++N IFTNLIL FI+LSS +LAA Sbjct: 866 RRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAA 925 Query: 920 EDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSV 979 EDP++ SFRN IL YFD FT IFT+EI LKMT +GAFLHKG+FCRNYFN+LD+LVV V Sbjct: 926 EDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGV 985 Query: 980 SLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLL 1039 SL+SFGIQSSAI+VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLL Sbjct: 986 SLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLL 1045 Query: 1040 QFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFD 1099 QFMFACIGVQLFKGK Y C+D +K EC+G +I YKDG+VD P+++ R W+NS F+FD Sbjct: 1046 QFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFD 1105 Query: 1100 NVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMN 1159 NVL+AMMALFTVSTFEGWP LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMN Sbjct: 1106 NVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMN 1165 Query: 1160 IFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNST 1219 IFVGFVIVTFQEQGE+EYKNCELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ Sbjct: 1166 IFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSS 1225 Query: 1220 YFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYF 1279 FEY+MFVLI+LNT+CLAMQHY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPK YF Sbjct: 1226 PFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYF 1285 Query: 1280 CDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVADGFQNA 1339 DAWNTFD+LIV+GSI+D+A++E +P E + V TA P N+ Sbjct: 1286 SDAWNTFDSLIVIGSIIDVALSEADPTESEN-------------VPVPTATP-----GNS 1327 Query: 1340 EENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVI 1399 EE++RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLI MLFFIYAVI Sbjct: 1328 EESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVI 1387 Query: 1400 GMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEP 1459 GMQ+FGK+A+ D +INRNNNFQTFPQAVLLLFRCATGEAWQ+IMLAC+PGK C PES+ Sbjct: 1388 GMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDY 1447 Query: 1460 SNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF 1519 + E CGS+FA+ YFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF Sbjct: 1448 NPGE--EYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEF 1505 Query: 1520 KRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVM 1579 KRIW+EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTVM Sbjct: 1506 KRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVM 1565 Query: 1580 FNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSM 1639 FNATLFALVRTAL+IKTE GNLEQANEELRA+IKKIWK+TSM Sbjct: 1566 FNATLFALVRTALKIKTE-------------------GNLEQANEELRAVIKKIWKKTSM 1606 Query: 1640 KLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGK-PSQRNALSLQAGLRT 1698 KLLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKFKKRKEQGLVGK P++ ++LQAGLRT Sbjct: 1607 KLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRT 1666 Query: 1699 LHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSA 1758 LHDIGPEIRRAIS DL +E E EDD+F+R G L GNHV++ SD R + Sbjct: 1667 LHDIGPEIRRAISCDLQDDE------PEETKREEEDDVFKRNGALLGNHVNHVNSDRRDS 1720 Query: 1759 FPQTFTTQRPLHINKAG-SSQGDTESPSHEKLVDST-FTPSSYSS------TGSNANINN 1810 QT TT RPLH+ + DTE P +S +++S T +NAN+NN Sbjct: 1721 LQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNN 1780 Query: 1811 ANNTALGRLPRPA----GYPSTVSTVEGHGPPLSPAIR--VQEVAWKLSSNRCHSRESQA 1864 AN + RP+ + S H P R V+ + + R S + Q Sbjct: 1781 ANMSKAAHGKRPSIGNLEHVSENGHHSSHKHDREPQRRSSVKRTRYYETYIRSDSGDEQL 1840 Query: 1865 AMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDD------------------- 1905 +E+ + D E S+E Y+DD Sbjct: 1841 PTICREDPEIHGYF-----RDPHCLGEQEYFSSEE-CYEDDSSPTWSRQNYGYYSRYPGR 1894 Query: 1906 ----------ENRQLTLPEEDK---RDIRQSPKRGFL-RSASLGRRASFHLECLKRQKDR 1951 + Q L ++D D R+SP+R L + + RR+SF+ ECL+RQ + Sbjct: 1895 NIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQSSQ 1954 Query: 1952 -----GGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWP 2006 +T LPLHL+ Q +AVAGL + +SP+ R +ATPPATP R W Sbjct: 1955 EEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWT 2014 Query: 2007 PQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAP 2066 P P +++E E+ +++N S PS+H SW P + R P SL VPS Sbjct: 2015 PCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTDEP----DISYRTFTPASLTVPSSFRNK 2070 Query: 2067 GRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGG 2126 SA SLVEAVLISEGLG++A+DPKF+ T E+ADACD+TI+EMESAA +L+G Sbjct: 2071 NSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLNGN 2130 Query: 2127 APQSPNGALLPFVNCRDAG-QDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2179 NG + P + +D QD G D R EE+L D + +++L Sbjct: 2131 VRPRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGR---DEEDLADEMICITTL 2181 >gi|192807298 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform c [Homo sapiens] Length = 2137 Score = 2726 bits (7065), Expect = 0.0 Identities = 1453/2197 (66%), Positives = 1659/2197 (75%), Gaps = 177/2197 (8%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYW+NDA+G + PW+YFV+L+I GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN--CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524 PTSETESVNTENV+G EGEN C L ISKSK SR WRRWNRF RR+CRAAVKS Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSV 523 Query: 525 VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584 FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LLALFT EML+KMYSLGLQAYF Sbjct: 524 TFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYF 583 Query: 585 VSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASL 644 VSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRLLRIFK+TR+W SLSNLVASL Sbjct: 584 VSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASL 643 Query: 645 LNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILT 704 LNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT+RSTFDNFPQ+LLTVFQILT Sbjct: 644 LNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILT 703 Query: 705 GEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764 GEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYILLNVFLAIAVDNLADAESL + Sbjct: 704 GEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNT 763 Query: 765 AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMD 824 AQKEE EEKERKK+AR S E K+ KP V + K+ +D Sbjct: 764 AQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD---------------NKVTID 806 Query: 825 DLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASA 879 D + E+EDK PYP E EE+E+EPE+P GPRPR +SEL++KEK P+PE SA Sbjct: 807 DYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSA 865 Query: 880 FFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIV 939 FFI S N R+ CH+++N IFTNLIL FI+LSS +LAAEDP++ SFRN IL YFD Sbjct: 866 FFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYA 925 Query: 940 FTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRV 999 FT IFT+EI LKMT +GAFLHKG+FCRNYFN+LD+LVV VSL+SFGIQSSAI+VVKILRV Sbjct: 926 FTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRV 985 Query: 1000 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS 1059 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Y C+ Sbjct: 986 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCT 1045 Query: 1060 DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE 1119 D +K EC+G +I YKDG+VD P+++ R W+NS F+FDNVL+AMMALFTVSTFEGWP Sbjct: 1046 DEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPA 1105 Query: 1120 LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN 1179 LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMNIFVGFVIVTFQEQGE+EYKN Sbjct: 1106 LLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKN 1165 Query: 1180 CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239 CELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ FEY+MFVLI+LNT+CLAMQ Sbjct: 1166 CELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQ 1225 Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIA 1299 HY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPK YF DAWNTFD+LIV+GSI+D+A Sbjct: 1226 HYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVA 1285 Query: 1300 ITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLV 1359 ++E + N+EE++RISITFFRLFRVMRLV Sbjct: 1286 LSEAD---------------------------------NSEESNRISITFFRLFRVMRLV 1312 Query: 1360 KLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNN 1419 KLLSRGEGIRTLLWTFIKSFQALPYVALLI MLFFIYAVIGMQ+FGK+A+ D +INRNN Sbjct: 1313 KLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNN 1372 Query: 1420 NFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFI 1479 NFQTFPQAVLLLFRCATGEAWQ+IMLAC+PGK C PES+ + E CGS+FA+ YFI Sbjct: 1373 NFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGE--EYTCGSNFAIVYFI 1430 Query: 1480 SFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDV 1539 SFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDPEAKGRIKHLDV Sbjct: 1431 SFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDV 1490 Query: 1540 VTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEG 1599 VTLLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTVMFNATLFALVRTAL+IKTE Sbjct: 1491 VTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTE-- 1548 Query: 1600 PSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKF 1659 GNLEQANEELRA+IKKIWK+TSMKLLDQVVPPAGDDEVTVGKF Sbjct: 1549 -----------------GNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKF 1591 Query: 1660 YATFLIQEYFRKFKKRKEQGLVGK-PSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEE 1718 YATFLIQ+YFRKFKKRKEQGLVGK P++ ++LQAGLRTLHDIGPEIRRAIS DL +E Sbjct: 1592 YATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDE 1651 Query: 1719 ELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG-SS 1777 E EDD+F+R G L GNHV++ SD R + QT TT RPLH+ + Sbjct: 1652 ------PEETKREEEDDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPP 1705 Query: 1778 QGDTESPSHEKLVDST-FTPSSYSS------TGSNANINNANNTALGRLPRPAGYPSTVS 1830 DTE P +S +++S T +NAN+NNAN + RP+ Sbjct: 1706 ASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHV 1765 Query: 1831 TVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTE--- 1887 + GH S+ H RE Q + + S DE D E Sbjct: 1766 SENGH-----------------HSSHKHDREPQRRSSVKRSDSGDEQLPTICREDPEIHG 1808 Query: 1888 ------ACSEPSLLSTEMLSYQDD-----------------------------ENRQLTL 1912 E S+E Y+DD + Q L Sbjct: 1809 YFRDPHCLGEQEYFSSEE-CYEDDSSPTWSRQNYGYYSRYPGRNIDSERPRGYHHPQGFL 1867 Query: 1913 PEEDK---RDIRQSPKRGFL-RSASLGRRASFHLECLKRQKDR-----GGDISQKTVLPL 1963 ++D D R+SP+R L + + RR+SF+ ECL+RQ + +T LPL Sbjct: 1868 EDDDSPVCYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQSSQEEVPSSPIFPHRTALPL 1927 Query: 1964 HLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEK 2023 HL+ Q +AVAGL + +SP+ R +ATPPATP R W P P +++E E+ ++ Sbjct: 1928 HLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQSEALDQ 1987 Query: 2024 LNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLI 2083 +N S PS+H SW P + R P SL VPS SA SLVEAVLI Sbjct: 1988 VNGSLPSLHRSSWYTDEP----DISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLI 2043 Query: 2084 SEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRD 2143 SEGLG++A+DPKF+ T E+ADACD+TI+EMESAA +L+G NG + P + +D Sbjct: 2044 SEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLNGNVRPRANGDVGPLSHRQD 2103 Query: 2144 AG-QDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2179 QD G D R EE+L D + +++L Sbjct: 2104 YELQDFGPGYSDEEPDPGR---DEEDLADEMICITTL 2137 >gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F subunit [Homo sapiens] Length = 1977 Score = 2274 bits (5894), Expect = 0.0 Identities = 1265/2189 (57%), Positives = 1497/2189 (68%), Gaps = 276/2189 (12%) Query: 16 QGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATIST 75 +G +P P+ AN AG PE PG A + + G++G Sbjct: 5 EGGKDTTPEPSPAN-----GAGPGPEWGLCPGPP---------AVEGESSGASG------ 44 Query: 76 VSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIF 135 T ++R Q+ K K +A R PRAL CLTL NP+RR+CISIVEWKPF+I+ILLTIF Sbjct: 45 -LGTPKRRNQHSKHKTVAVASAQRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIF 103 Query: 136 ANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGW 195 ANCVAL +YIPFPEDDSN N NLE+VEY+FL+IFTVE LK++AYGL+ HP+AY+RNGW Sbjct: 104 ANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGW 163 Query: 196 NLLDFIIVVVGLFSAILEQATKADG-ANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSL 254 NLLDFIIVVVGLFS +LEQ G A GGK GFDVKALRAFRVLRPLRLVSGVPSL Sbjct: 164 NLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSL 223 Query: 255 QVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPS 314 +VLNSI+KA+VPLLHIALLVLFVIIIYAIIGLELF+G+MHKTCY +D+ AE+DPS Sbjct: 224 HIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLG--SDMEAEEDPS 281 Query: 315 PCALETGHGRQCQ-NGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 PCA +G GR C N T C+ W GP GITNFDNF FAMLTVFQC+TMEGWTDVLYW+ Sbjct: 282 PCA-SSGSGRACTLNQTECRGRWPGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQ 340 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA+G + PW+YFV+L+I GSFFVLNLVLGVLSGEFSKEREKAKARGDFQK REKQQ+EED Sbjct: 341 DAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKQREKQQMEED 400 Query: 434 LKGYLDWITQAEDIDPEN----------EDEGMDEEKPR--------------------- 462 L+GYLDWITQAE++D E+ +EG +P+ Sbjct: 401 LRGYLDWITQAEELDMEDPSADDNLGSMAEEGRAGHRPQLAELTNRRRGRLRWFSHSTRS 460 Query: 463 ------NMSMPTSETESVNTENVAGGDIEG--ENCGARLAHRISKSKFSRYWRRWNRFCR 514 + S+P S+T S+ + EG +C R ++I K++ R RR NR R Sbjct: 461 THSTSSHASLPASDTGSMTETQGDEDEEEGALASC-TRCLNKIMKTRVCRRLRRANRVLR 519 Query: 515 RKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLK 574 +CR AVKSN YW V+ LVFLNTLTIASEH+ QP WLT++Q+ ANK LL LFT EMLLK Sbjct: 520 ARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQIQEYANKVLLCLFTVEMLLK 579 Query: 575 MYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYW 634 +Y LG AY S FNRFDCFVVCGGILET LVE M PLGISVLRCVRLLRIFK+TR+W Sbjct: 580 LYGLGPSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHW 639 Query: 635 NSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQ 694 SLSNLVASLLNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFD+ T+RSTFD FPQ Sbjct: 640 ASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQ 699 Query: 695 SLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVD 754 +LLTVFQILTGEDWN VMYDGIMAYGGP FPGMLVCIYFIILFICGNYILLNVFLAIAVD Sbjct: 700 ALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVD 759 Query: 755 NLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGE 814 NLA ++ T+ K E+ E+ P++ + LV P V + +EE + Sbjct: 760 NLASGDAGTAKDKGGEKSNEKD------LPQENEGLV--PGVEKEEEEGARREGA----- 806 Query: 815 SPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPM 874 D++ E E+ EE+EEE E L E+ KEK VP+ Sbjct: 807 ----------DMEEEEEEE-----------EEEEEEEEEEGAGGVELLQEVVPKEKVVPI 845 Query: 875 PEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILF 934 PE SAFF S N R CH +++ +FTNLIL FI+LSS+SLAAEDP++ SFRNHIL Sbjct: 846 PEGSAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRNHILG 905 Query: 935 YFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVV 994 YFD FT+IFT+EI LKMT +GAFLH+GSFCR++FN+LDLLVVSVSLISFGI SSAI+VV Sbjct: 906 YFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHSSAISVV 965 Query: 995 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGK 1054 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Sbjct: 966 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGK 1025 Query: 1055 LYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTF 1114 YTC+D +K T ECKG+++ Y DG+V P+++ R W NS F+FDNVL+AMMALFTVSTF Sbjct: 1026 FYTCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTF 1085 Query: 1115 EGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE 1174 EGWP LLY++ID++ ED GPIYNYRVEIS+FFI+YIIIIAFFMMNIFVGFVI+TF+ QGE Sbjct: 1086 EGWPALLYKAIDAYAEDHGPIYNYRVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGE 1145 Query: 1175 QEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTI 1234 QEY+NCELDKNQRQCVEYALKA+PLRRYIPKN HQY+VW VNS FEYLMF+LILLNT+ Sbjct: 1146 QEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTV 1205 Query: 1235 CLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGS 1294 LAMQHY Q+ F AM+ILNM+FTGLFT+EM+LK+IAFKPKHYF DAWNTFDALIVVGS Sbjct: 1206 ALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFTDAWNTFDALIVVGS 1265 Query: 1295 IVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRLFR 1354 IVDIA+TEVN H +++E++SRISITFFRLFR Sbjct: 1266 IVDIAVTEVNNGGHLG--------------------------ESSEDSSRISITFFRLFR 1299 Query: 1355 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1414 VMRLVKLLS+GEGIRTLLWTFIKSFQALPYVALLI M+FFIYAVIGMQ+FGK+AL D T+ Sbjct: 1300 VMRLVKLLSKGEGIRTLLWTFIKSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQ 1359 Query: 1415 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1474 INRNNNFQTFPQAVLLLFRCATGEAWQ+IMLA +PG +C PES+ E CGS+FA Sbjct: 1360 INRNNNFQTFPQAVLLLFRCATGEAWQEIMLASLPGNRCDPESDFGPGE--EFTCGSNFA 1417 Query: 1475 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1534 + YFISF+MLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDP AKGRI Sbjct: 1418 IAYFISFFMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRI 1477 Query: 1535 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1594 KHLDVV LLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTV FNATLFALVRT+L+I Sbjct: 1478 KHLDVVALLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVTFNATLFALVRTSLKI 1537 Query: 1595 KTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEV 1654 KTE GNLEQAN+ELR +IKKIWKR KLLD+V+PP ++EV Sbjct: 1538 KTE-------------------GNLEQANQELRIVIKKIWKRMKQKLLDEVIPPPDEEEV 1578 Query: 1655 TVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALS-LQAGLRTLHDIGPEIRRAISGD 1713 TVGKFYATFLIQ+YFRKF++RKE+GL+G + + S LQAGLR+L D+GPE+R+A++ D Sbjct: 1579 TVGKFYATFLIQDYFRKFRRRKEKGLLGNDAAPSTSSALQAGLRSLQDLGPEMRQALTCD 1638 Query: 1714 LTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINK 1773 EEE +E V E D+ T + +++ Sbjct: 1639 TEEEEE---EGQEGVEEEDEKDL---------------------------ETNKATMVSQ 1668 Query: 1774 AGSSQGDTES---PSHEKLVDS-TFTPSS---YSSTGSNANINNANNTALGRLPRPAGYP 1826 + +G S P ++L DS +F PS + T S ++ A + R G Sbjct: 1669 PSARRGSGISVSLPVGDRLPDSLSFGPSDDDRGTPTSSQPSVPQAGSNTHRR-----GSG 1723 Query: 1827 STVSTV--EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNH 1884 + + T+ EG+ P GQ + +DE ++++ Sbjct: 1724 ALIFTIPEEGNSQP-------------------------KGTKGQNKQDEDEEVPDRLSY 1758 Query: 1885 DTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKR--DIRQSPKRGFLRSASLGRRASFHL 1942 E P L P +R D P+R L GR+ SF + Sbjct: 1759 LDEQAGTPPC-------------SVLLPPHRAQRYMDGHLVPRRRLLPPTPAGRKPSFTI 1805 Query: 1943 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 2002 +CL+RQ G LP+ +H+ R+ P +ATPP Sbjct: 1806 QCLQRQ----GSCED---LPIPGTYHRG-----------RNSGPNRAQGSWATPP----Q 1843 Query: 2003 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2062 RG L EG L G SS R L VP Sbjct: 1844 RGRLLYAPLLLVEEGAAGEGYL-------------------GRSSGPLRTF-TCLHVPGT 1883 Query: 2063 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2122 P GSA SLVEAVLISEGLG FA+DP+F+ + QE+ADAC +T++EM++AA ++ Sbjct: 1884 HSDPSHGKRGSADSLVEAVLISEGLGLFARDPRFVALAKQEIADACRLTLDEMDNAASDL 1943 Query: 2123 LSGGAPQ--SPNGALLPFVNCRDAGQDRA 2149 L+ G S ++L + D G + A Sbjct: 1944 LAQGTSSLYSDEESILSRFDEEDLGDEMA 1972 >gi|110349767 calcium channel, voltage-dependent, L type, alpha 1S subunit [Homo sapiens] Length = 1873 Score = 2273 bits (5890), Expect = 0.0 Identities = 1173/1749 (67%), Positives = 1384/1749 (79%), Gaps = 89/1749 (5%) Query: 77 SSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFA 136 SS Q + + +PKK RPPRAL CLTL+NP+R+ACISIVEWKPFE IILLTIFA Sbjct: 4 SSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFA 63 Query: 137 NCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWN 196 NCVALA+Y+P PEDD+N+ N LE++EY FLI+F++EA +K+IAYG LFH +AYLR+GWN Sbjct: 64 NCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWN 123 Query: 197 LLDFIIVVVGLFSAILEQATKADGANA-LGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQ 255 +LDF IV +G+F+ ILEQ A + KGAG DVKALRAFRVLRPLRLVSGVPSLQ Sbjct: 124 VLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQ 183 Query: 256 VVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGIADVPAEDDP 313 VVLNSI KAM+PL HIALLVLF++IIYAIIGLELF GKMHKTCY + +A V E+ P Sbjct: 184 VVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEE-P 242 Query: 314 SPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWV 372 SPCA TG GR+C NG+ C+ GW GP HGIT+FDNF F+MLTV+QCITMEGWTDVLYWV Sbjct: 243 SPCA-RTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWV 301 Query: 373 NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEE 432 NDA+G +WPWIYFVTLI++GSFF+LNLVLGVLSGEF+KEREKAK+RG FQKLREKQQL+E Sbjct: 302 NDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDE 361 Query: 433 DLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGAR 492 DL+GY+ WITQ E +D E+ EG ++ S+TES+ +I G N Sbjct: 362 DLRGYMSWITQGEVMDVEDFREGK-----LSLDEGGSDTESLY-------EIAGLN---- 405 Query: 493 LAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWL 552 +F R+WR+WNR R KC VKS VFYWLVI +V LNTL+IASEH+NQP WL Sbjct: 406 -----KIIQFIRHWRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWL 460 Query: 553 TEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMS 612 T +QD AN+ LL+LFT EML+KMY LGL+ YF+S+FNRFDCFVVC GILE +LVE+ M+ Sbjct: 461 TRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMT 520 Query: 613 PLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQL 672 PLGISVLRC+RLLRIFKIT+YW SLSNLVASLLNS+RSIASLLLLLFLFI+IF+LLGMQL Sbjct: 521 PLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQL 580 Query: 673 FGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIY 732 FGG+++F++ + RRS FDNFPQ+L++VFQ+LTGEDW S+MY+GIMAYGGPS+PGMLVCIY Sbjct: 581 FGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIY 640 Query: 733 FIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVE 792 FIILF+CGNYILLNVFLAIAVDNLA+AESLTSAQK + EEK+R+K+++ P+K +E E Sbjct: 641 FIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEEKKRRKMSK-GLPDKSEE--E 697 Query: 793 KPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPE 852 K + + E+K + + I P K+ +D+ + N NE K PYP+ + G+++E+EPE Sbjct: 698 KSTMAKKLEQKPKGEGI------PTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPE 751 Query: 853 MPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILL 912 +P+ PRPRPL+EL LKEKAVP+PEAS+FFIFS N+ R+ CHRIVN T FTN IL FILL Sbjct: 752 IPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILL 811 Query: 913 SSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNIL 972 SS +LAAEDP++ S RN IL +FDI FT++FT+EI LKMT YGAFLHKGSFCRNYFN+L Sbjct: 812 SSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNML 871 Query: 973 DLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI 1032 DLLVV+VSLIS G++SSAI+VVKILRVLRVLRPLRAINRAKGLKHVVQC+FVAI TIGNI Sbjct: 872 DLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNI 931 Query: 1033 VIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWE 1092 V+VTTLLQFMFACIGVQLFKGK + C+D SK TE EC+G Y YKDG+ ++ R W Sbjct: 932 VLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWV 991 Query: 1093 NSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIII 1152 +S F FDNVL+AMM+LFTVSTFEGWP+LLY++IDS+ ED GPIYN RVE++IFFIIYII+ Sbjct: 992 HSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIIL 1051 Query: 1153 IAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKV 1212 IAFFMMNIFVGFVIVTFQEQGE EYKNCELDKNQRQCV+YALKARPLR YIPKN +QY+V Sbjct: 1052 IAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQV 1111 Query: 1213 WYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIA 1272 WY+V S+YFEYLMF LI+LNTICL MQHY QS +ILN+ FT +FT+EMILKL+A Sbjct: 1112 WYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMA 1171 Query: 1273 FKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPV 1332 FK + YF D WN FD LIV+GSI+D+ ++E++ T + S G C + Sbjct: 1172 FKARGYFGDPWNVFDFLIVIGSIIDVILSEID----TFLASSGGLYC------------L 1215 Query: 1333 ADGFQNA--EENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIV 1390 G N +E++RIS FFRLFRVMRL+KLLSR EG+RTLLWTFIKSFQALPYVALLIV Sbjct: 1216 GGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIV 1275 Query: 1391 MLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPG 1450 MLFFIYAVIGMQ+FGKIAL D T+INRNNNFQTFPQAVLLLFRCATGEAWQ+I+LAC G Sbjct: 1276 MLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYG 1335 Query: 1451 KKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSI 1510 K C PES+ + E CG++FA +YFISFYMLCAFL+INLFVAVIMDNFDYLTRDWSI Sbjct: 1336 KLCDPESDYAPGE--EYTCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSI 1393 Query: 1511 LGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNM 1570 LGPHHLDEFK IWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK CPHRVACKRLV MNM Sbjct: 1394 LGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNM 1453 Query: 1571 PLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAII 1630 PLNSDGTV FNATLFALVRTAL+IKTE GN EQANEELRAII Sbjct: 1454 PLNSDGTVTFNATLFALVRTALKIKTE-------------------GNFEQANEELRAII 1494 Query: 1631 KKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNAL 1690 KKIWKRTSMKLLDQV+PP GDDEVTVGKFYATFLIQE+FRKF KR+E+ G +++ + Sbjct: 1495 KKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEE-YYGYRPKKDIV 1553 Query: 1691 SLQAGLRTL-HDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVS 1749 +QAGLRT+ + PEI R +SGDL AEEEL++AM V AA E+ IFRR GGLFG + Sbjct: 1554 QIQAGLRTIEEEAAPEICRTVSGDLAAEEELERAM---VEAAMEEGIFRRTGGLFGQVDN 1610 Query: 1750 YYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANIN 1809 + + ++ P QRPL A + ESP + F ++ + AN N Sbjct: 1611 FLER--TNSLPPVMANQRPLQF--AEIEMEEMESP----VFLEDFPQDPRTNPLARANTN 1662 Query: 1810 NAN-NTALG 1817 NAN N A G Sbjct: 1663 NANANVAYG 1671 Score = 49.7 bits (117), Expect = 3e-05 Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 24/151 (15%) Query: 2006 PPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGA 2065 PP P R+E ++ +S+ S+H E TP +R R + S+ A Sbjct: 1737 PPAPCQCPRVESSMPEDRKSSTPGSLH-----EETPH------SRSTRENT----SRCSA 1781 Query: 2066 PGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSG 2125 P + + L++ L+ GLG A D FI T Q LADAC M EE+E A +L G Sbjct: 1782 P------ATALLIQKALVRGGLGTLAADANFIMATGQALADACQMEPEEVEIMATELLKG 1835 Query: 2126 GAPQSPNGALLPFVNCRDAGQDRAGGEEDAG 2156 ++P G + + C + G ++ G Sbjct: 1836 --REAPEG-MASSLGCLNLGSSLGSLDQHQG 1863 >gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo sapiens] Length = 2261 Score = 765 bits (1976), Expect = 0.0 Identities = 411/907 (45%), Positives = 568/907 (62%), Gaps = 91/907 (10%) Query: 790 LVEKPAVGESKEEKIELKSITADGESPPATK--INMDDLQPNENEDKSPYPNPETTGEED 847 +V P+ ++ K K + PPA +N +Q N+N + P P E +E+ Sbjct: 1146 IVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKEEEKKEE 1205 Query: 848 EEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLIL 907 EE+ GP+P MP S+ FI S+ N R CH I+N F IL Sbjct: 1206 EEDDRGEDGPKP--------------MPPYSSMFILSTTNPLRRLCHYILNLRYFEMCIL 1251 Query: 908 FFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRN 967 I +SSI+LAAEDPVQ + RN++L YFD VFT +FT E+ +KM G LH+G++ R+ Sbjct: 1252 MVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRD 1311 Query: 968 YFNILDLLVVSVSLISFGIQSSA----INVVKILRVLRVLRPLRAINRAKGLKHVVQCVF 1023 +NILD +VVS +L++F ++ IN +K LRVLRVLRPL+ I R LK V CV Sbjct: 1312 LWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVV 1371 Query: 1024 VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH 1083 +++ + NI+IV L F+FA + VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV Sbjct: 1372 NSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVK- 1430 Query: 1084 PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS 1143 + R W+ +F +DNVL A++ LFTVST EGWP++L S+D+ E++GP YR+E+S Sbjct: 1431 --ARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMS 1488 Query: 1144 IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI 1203 IF+++Y ++ FF +NIFV +I+TFQEQG++ + L+KN+R C+++A+ A+PL R++ Sbjct: 1489 IFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHM 1548 Query: 1204 PKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGL 1261 P+N+ QY++W V S FEY + +I LNTI L M+ YG S ++ A+ + N++FT L Sbjct: 1549 PQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSL 1608 Query: 1262 FTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSH 1321 F++E +LK++AF +YF DAWN FD + V+GSI DI +TE Sbjct: 1609 FSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITDILVTEFG----------------- 1651 Query: 1322 PPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQA 1381 N+ I+++F RLFR RL+KLL +G IR LLWTF++SF+A Sbjct: 1652 --------------------NNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKA 1691 Query: 1382 LPYVALLIVMLFFIYAVIGMQVFGKIALN--------DTTEINRNNNFQTFPQAVLLLFR 1433 LPYV LLI MLFFIYA+IGMQVFG I ++ D +I +NNF+TF QA++LLFR Sbjct: 1692 LPYVCLLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFR 1751 Query: 1434 CATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLF 1493 ATGEAW +IML+C+ GK C NS CG+ FA FYF+SF LC+FL++NLF Sbjct: 1752 SATGEAWHNIMLSCLSGKPC-----DKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLF 1806 Query: 1494 VAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFG 1553 VAVIMDNF+YLTRD SILGPHHLDE+ R+WAEYDP A GRI + D+ +LLR I PPLG G Sbjct: 1807 VAVIMDNFEYLTRDSSILGPHHLDEYVRVWAEYDPAACGRIHYKDMYSLLRVISPPLGLG 1866 Query: 1554 KLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPF 1613 K CPHRVACKRL+ M++P+ D TV FN+TL AL+RTAL IK +G GA+ Sbjct: 1867 KKCPHRVACKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKG--------GADK-- 1916 Query: 1614 RPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1673 +Q + ELR + IW S K LD +V P ++TVGK YA +I EY+R+ K Sbjct: 1917 ------QQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSK 1970 Query: 1674 KRKEQGL 1680 +K Q + Sbjct: 1971 AKKLQAM 1977 Score = 671 bits (1730), Expect = 0.0 Identities = 383/827 (46%), Positives = 507/827 (61%), Gaps = 64/827 (7%) Query: 18 SNYGSPRPA-HANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTV 76 + +G PA + + AAAG+ GA S Q G G + Sbjct: 2 ARFGDEMPARYGGGGSGAAAGVVVGSGGGRGAGGSRQG-----------GQPGAQRMYKQ 50 Query: 77 SSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLT 133 S QR R Y P +Q T R +L + N +R+ I EW PFE +IL T Sbjct: 51 SMAQRARTMALYNPIPVRQNCLTVNR---SLFLFSEDNVVRKYAKKITEWPPFEYMILAT 107 Query: 134 IFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN 193 I ANC+ LA+ P+DD + L+ E F+ IF EA +K+IA G FH +YLRN Sbjct: 108 IIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRN 167 Query: 194 GWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPS 253 GWN++DF++V+ G+ + + G FD++ LRA RVLRPL+LVSG+PS Sbjct: 168 GWNVMDFVVVLTGILATV----------------GTEFDLRTLRAVRVLRPLKLVSGIPS 211 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 LQVVL SI+KAM+PLL I LL+ F I+I+AIIGLE +MGK H TC+ +EG D+ E P Sbjct: 212 LQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCF-EEGTDDIQGES-P 269 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 +PC E R C NGT C+P W+GP +GIT FDN FA+LTVFQCITMEGWTD+LY N Sbjct: 270 APCGTEEP-ARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSN 328 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA G W W+YF+ LIIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E + Sbjct: 329 DASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERE 388 Query: 434 LKGYLDWITQAEDIDPENEDEGMDEEKP-----RNMSMPTSETESVNTENVAGGDIEGEN 488 L GY++WI++AE++ ++ ++ P R ++ S+T+ +N E + + Sbjct: 389 LNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIKKSKTDLLNPEEAEDQLADIAS 448 Query: 489 CG---ARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEH 545 G AR + + +K + S ++ + R R R VK+ FYW V+ LV LNTL +A H Sbjct: 449 VGSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVH 508 Query: 546 YNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETIL 605 YNQP WL++ A L LF +EM +KMY LG + YF S FN FDC V+ G I E I Sbjct: 509 YNQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIW 568 Query: 606 VETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIF 665 K + GISVLR +RLLRIFK+T+YW SL NLV SLLNS++SI SLL LLFLFI++F Sbjct: 569 AVIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVF 628 Query: 666 SLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP 725 +LLGMQLFGG+FNFDE T + FD FP +++TVFQILTGEDWN VMYDGI + GG Sbjct: 629 ALLGMQLFGGQFNFDE-GTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQ-G 686 Query: 726 GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERK--------- 776 GM+ IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EEEE +K Sbjct: 687 GMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEV 746 Query: 777 ------KLARTASPEKKQELVEKPA--VGESKEEKIELKSITADGES 815 A + K+Q+ +KPA V E + ++ +++ A E+ Sbjct: 747 AEVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREA 793 Score = 202 bits (513), Expect = 4e-51 Identities = 176/705 (24%), Positives = 317/705 (44%), Gaps = 120/705 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 + K+++ + + P ++ L+ NP+RR C I+ + FE+ IL+ I + + Sbjct: 1200 EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI 1259 Query: 140 ALAIYIPFPEDDSNATNSNLERV-EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198 ALA P NA +N+ R +Y+F +FT E +K+I GL+ H AY R+ WN+L Sbjct: 1260 ALAAEDPV---QPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNIL 1316 Query: 199 DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258 DFI+V L + +K N +K+LR RVLRPL+ + +P L+ V Sbjct: 1317 DFIVVSGALVAFAFTGNSKGKDINT---------IKSLRVLRVLRPLKTIKRLPKLKAVF 1367 Query: 259 NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK-MHKTCYNQEGIADVPAEDDPSPCA 317 + ++ ++ + +I ++ + + I+A++ ++LF GK H T ++E D Sbjct: 1368 DCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDC---------- 1417 Query: 318 LETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV- 376 G + V + K+ ++DN +A+LT+F T EGW VL DA Sbjct: 1418 --RGKYLLYEKNEVKARDREWKKYEF-HYDNVLWALLTLFTVSTGEGWPQVLKHSVDATF 1474 Query: 377 --------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQ 428 R I++V ++ FF +N+ + ++ F ++ GD K+ E+ Sbjct: 1475 ENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KMMEEY 1525 Query: 429 QLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGEN 488 LE++ + +D+ A KP MP Sbjct: 1526 SLEKNERACIDFAISA---------------KPLTRHMP--------------------- 1549 Query: 489 CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ 548 ++K S +R W V S F + ++ ++ LNT+ + + Y Sbjct: 1550 ----------QNKQSFQYRMWQ---------FVVSPPFEYTIMAMIALNTIVLMMKFYGA 1590 Query: 549 PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVET 608 N +LF+ E +LK+ + G+ YF +N FD V G I + ILV Sbjct: 1591 SVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITD-ILVTE 1649 Query: 609 KIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLL 668 + + +S LR R R+ K+ R ++ L+ + + S +++ + LL+ + I++++ Sbjct: 1650 FGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1709 Query: 669 GMQLFGG--------KFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAY 719 GMQ+FG + DE Q T + F F Q+L+ +F+ TGE W+++M + Sbjct: 1710 GMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGK 1769 Query: 720 GGPSFPGML--------VCIYFI-ILFICGNYILLNVFLAIAVDN 755 G+L YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1770 PCDKNSGILTRECGNEFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1813 Score = 144 bits (362), Expect = 1e-33 Identities = 179/785 (22%), Positives = 325/785 (41%), Gaps = 161/785 (20%) Query: 480 AGGDIEGENCGARLAHRISKSKFSRYWRRWNRF-CRRKCRAAVKS-------NV------ 525 AGG +G GA+ ++ S ++ +R +N R+ C +S NV Sbjct: 33 AGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAK 92 Query: 526 -------FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKM 575 F ++++ + N + +A E + + ++E D + +F E +K+ Sbjct: 93 KITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKI 152 Query: 576 YSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT 631 +LG +Y + +N D VV GIL T+ E + LR VR+LR K+ Sbjct: 153 IALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTE------FDLRTLRAVRVLRPLKLV 206 Query: 632 RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF-------DEMQT 684 SL ++ S++ ++ + + LLLF I+IF+++G++ + GKF+ D++Q Sbjct: 207 SGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQG 266 Query: 685 RR------------------------------STFDNFPQSLLTVFQILTGEDWNSVMYD 714 + FDN ++LTVFQ +T E W ++Y+ Sbjct: 267 ESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYN 326 Query: 715 GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE 774 A G +YFI L I G++ +LN+ L + A +E+E Sbjct: 327 SNDASGNT-----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERE 368 Query: 775 RKKLARTASPEKKQELVEKPAVGE----SKEEKIELKSITADGES--PPATKINMDDLQP 828 R + R ++Q+ +E+ G SK E++ L DGE P + ++ Sbjct: 369 RVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIK- 427 Query: 829 NENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNR 888 + K+ NPE ED+ VG P + +K + E S FF R Sbjct: 428 ---KSKTDLLNPEEA--EDQLADIASVGS---PFARASIKSAKL---ENSTFF-HKKERR 475 Query: 889 FRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEI 948 R R+V F +L + L+++ +A Q + + L+Y + +F +F E+ Sbjct: 476 MRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQ-PEWLSDFLYYAEFIFLGLFMSEM 534 Query: 949 ALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRP 1005 +KM G + + FN D V+ S+ I+ + +LR LR+LR Sbjct: 535 FIKMYGLGT----RPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRI 590 Query: 1006 LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT 1065 + L+++V + ++++I +++ + L +FA +G+QLF G+ + + + T Sbjct: 591 FKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQ-FNFDEGTPPT 649 Query: 1066 EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI 1125 +FD AA+M +F + T E W E++Y I Sbjct: 650 -------------------------------NFDTFPAAIMTVFQILTGEDWNEVMYDGI 678 Query: 1126 DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEY 1177 S +G + SI+FI+ + + ++N+F+ + +T EQ E+E Sbjct: 679 KSQGGVQGGMV-----FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEA 733 Query: 1178 KNCEL 1182 N +L Sbjct: 734 ANQKL 738 Score = 114 bits (285), Expect = 1e-24 Identities = 96/331 (29%), Positives = 162/331 (48%), Gaps = 33/331 (9%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936 + F+FS +N R +I F +IL I+ + I LA E P + + L Sbjct: 77 SLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDT 136 Query: 937 DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI-SFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV ++ + G + ++ Sbjct: 137 EPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFD----LR 192 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ +FA IG++ + GK Sbjct: 193 TLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252 Query: 1056 YT------CSDSSKQTEAEC--KGNYITYKDGEVDHPIIQPRSWE---NSKFDFDNVLAA 1104 +T D ++ A C + T +G P WE N FDN+L A Sbjct: 253 HTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPY-----WEGPNNGITQFDNILFA 307 Query: 1105 MMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 1164 ++ +F T EGW +LLY S D+ G +N+ ++FI III +FFM+N+ +G Sbjct: 308 VLTVFQCITMEGWTDLLYNSNDA----SGNTWNW-----LYFIPLIIIGSFFMLNLVLGV 358 Query: 1165 VIVTFQEQGEQ-EYKNCELDKNQRQCVEYAL 1194 + F ++ E+ E + L ++Q +E L Sbjct: 359 LSGEFAKERERVENRRAFLKLRRQQQIEREL 389 Score = 104 bits (260), Expect = 8e-22 Identities = 74/316 (23%), Positives = 138/316 (43%), Gaps = 64/316 (20%) Query: 1195 KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL 1254 K R +R YI + +V + F + + L+ LNT+C+A+ HY Q + Sbjct: 472 KERRMRFYIRR---------MVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYA 522 Query: 1255 NMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPS 1314 +F GLF EM +K+ + YF ++N FD +++GSI ++ + P Sbjct: 523 EFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPG-------- 574 Query: 1315 MGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1374 + I+ R R++R+ K+ +R L+ + Sbjct: 575 ----------------------------TSFGISVLRALRLLRIFKVTKYWASLRNLVVS 606 Query: 1375 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1434 + S +++ + L+ + ++A++GMQ+FG + E NF TFP A++ +F+ Sbjct: 607 LLNSMKSIISLLFLLFLFIVVFALLGMQLFG--GQFNFDEGTPPTNFDTFPAAIMTVFQI 664 Query: 1435 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1494 TGE W ++M ++G G F++ YFI + + ++N+F+ Sbjct: 665 LTGEDWNEVMY-------------DGIKSQGGVQGGMVFSI-YFIVLTLFGNYTLLNVFL 710 Query: 1495 AVIMDNF---DYLTRD 1507 A+ +DN LT+D Sbjct: 711 AIAVDNLANAQELTKD 726 Score = 82.0 bits (201), Expect = 6e-15 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 62/297 (20%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N + L + S A + L +F +F++E LKV+A+G+L Sbjct: 1567 PFEYTIMAMIALNTIVLMMKF---YGASVAYENALRVFNIVFTSLFSLECVLKVMAFGIL 1623 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + G N + ++ LR FR R Sbjct: 1624 ----NYFRDAWNIFDFVTVLGSITDILVTEF----GNNFI-------NLSFLRLFRAARL 1668 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F GI Sbjct: 1669 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF---------GNIGI 1719 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 DV ED T H NF F A++ +F+ T E Sbjct: 1720 -DVEDEDSDEDEFQITEH---------------------NNFRTFFQALMLLFRSATGEA 1757 Query: 365 WTDVLY-------------WVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ + G ++ + YFV+ I + SF +LNL + V+ F Sbjct: 1758 WHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1814 Score = 53.5 bits (127), Expect = 2e-06 Identities = 69/324 (21%), Positives = 118/324 (36%), Gaps = 103/324 (31%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + ++ F G+F E +K+IA F Sbjct: 100 FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159 Query: 1274 KPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVA 1333 Y + WN D ++V+ I+ TE + Sbjct: 160 HKGSYLRNGWNVMDFVVVLTGILATVGTEFD----------------------------- 190 Query: 1334 DGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLF 1393 + R RV+R +KL+S ++ +L + +K+ L + LL+ Sbjct: 191 -------------LRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAI 237 Query: 1394 FIYAVIGMQVF-GKI-----------------ALNDTTEINR---------------NNN 1420 I+A+IG++ + GK A T E R NN Sbjct: 238 LIFAIIGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNG 297 Query: 1421 FQTFPQ---AVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFY 1477 F AVL +F+C T E W D++ NS + G+++ Y Sbjct: 298 ITQFDNILFAVLTVFQCITMEGWTDLLY---------------NSNDAS---GNTWNWLY 339 Query: 1478 FISFYMLCAFLIINLFVAVIMDNF 1501 FI ++ +F ++NL + V+ F Sbjct: 340 FIPLIIIGSFFMLNLVLGVLSGEF 363 >gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B subunit [Homo sapiens] Length = 2339 Score = 758 bits (1956), Expect = 0.0 Identities = 432/985 (43%), Positives = 594/985 (60%), Gaps = 109/985 (11%) Query: 764 SAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESP----PAT 819 + +KE E++ +K A +K++EL + +E +L++ P P+T Sbjct: 991 AVEKETTEKEATEKEAEIVEADKEKELRNH----QPREPHCDLETSGTVTVGPMHTLPST 1046 Query: 820 KINMDDLQPNENEDK-------SPYPNPETTGEEDEEEPEMPVGPRPR----PLSELHLK 868 + + QP + +++ S P+P T P M GP P + L+ Sbjct: 1047 CLQKVEEQPEDADNQRNVTRMGSQPPDPNTI----VHIPVMLTGPLGEATVVPSGNVDLE 1102 Query: 869 EKAV----------------PMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILL 912 +A P+ S+ F S N R CH IV F +IL I L Sbjct: 1103 SQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFCHYIVTMRYFEVVILVVIAL 1162 Query: 913 SSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNIL 972 SSI+LAAEDPV+ S RN+ L Y D +FT +FT E+ +KM G LH G++ R+ +NIL Sbjct: 1163 SSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNIL 1222 Query: 973 DLLVVSVSLISFGIQSSA---INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTI 1029 D +VVS +L++F S IN +K LRVLRVLRPL+ I R LK V CV +++ + Sbjct: 1223 DFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNV 1282 Query: 1030 GNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPR 1089 NI+IV L F+FA I VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV+ QPR Sbjct: 1283 LNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELERDCRGQYLDYEKEEVE---AQPR 1339 Query: 1090 SWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIY 1149 W+ F +DNVL A++ LFTVST EGWP +L S+D+ E++GP YR+E+SIF+++Y Sbjct: 1340 QWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVY 1399 Query: 1150 IIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH- 1208 ++ FF +NIFV +I+TFQEQG++ C L+KN+R C+++A+ A+PL RY+P+N+ Sbjct: 1400 FVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFAISAKPLTRYMPQNRQS 1459 Query: 1209 -QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMI 1267 QYK W V S FEY + +I LNT+ L M+ Y +++ + LN++FT +F++E + Sbjct: 1460 FQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECV 1519 Query: 1268 LKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVL 1327 LK+IAF +YF DAWN FD + V+GSI DI +TE+ Sbjct: 1520 LKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEI------------------------ 1555 Query: 1328 TAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVAL 1387 AE N+ I+++F RLFR RL+KLL +G IR LLWTF++SF+ALPYV L Sbjct: 1556 -----------AETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCL 1604 Query: 1388 LIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLAC 1447 LI MLFFIYA+IGMQVFG IAL+D T INR+NNF+TF QA++LLFR ATGEAW +IML+C Sbjct: 1605 LIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSC 1664 Query: 1448 MPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRD 1507 + + C E +N+TE CGS FA FYF+SF LC+FL++NLFVAVIMDNF+YLTRD Sbjct: 1665 LSNQAC---DEQANATE----CGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRD 1717 Query: 1508 WSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVS 1567 SILGPHHLDEF R+WAEYDP A GRI + D+ +L+ + PPLG GK CP RVA KRLV Sbjct: 1718 SSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVR 1777 Query: 1568 MNMPL-NSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEEL 1626 MNMP+ N D TV F +TL AL+RTAL IK P+ ++ H Q + EL Sbjct: 1778 MNMPISNEDMTVHFTSTLMALIRTALEIKL--APAGTKQH--------------QCDAEL 1821 Query: 1627 RAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKE--QGLVGKP 1684 R I +W K LD +VPP DE+TVGK YA +I +++++ K ++ Q G Sbjct: 1822 RKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAPGGL 1881 Query: 1685 SQRNALSLQAGLR-TLHDIGPEIRR 1708 SQ +SL L+ TL P + R Sbjct: 1882 SQMGPVSLFHPLKATLEQTQPAVLR 1906 Score = 648 bits (1671), Expect = 0.0 Identities = 371/803 (46%), Positives = 486/803 (60%), Gaps = 59/803 (7%) Query: 89 PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFP 148 P KQ T R +L + N +R+ I EW PFE +IL TI ANC+ LA+ P Sbjct: 63 PVKQNCFTVNR---SLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLP 119 Query: 149 EDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLF 208 + D + L+ E F+ IF EA +K+IA G +FH +YLRNGWN++DF++V+ G+ Sbjct: 120 DGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGI- 178 Query: 209 SAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPL 268 L G FD++ LRA RVLRPL+LVSG+PSLQVVL SI+KAMVPL Sbjct: 179 ---------------LATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPL 223 Query: 269 LHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQN 328 L I LL+ F I+++AIIGLE +MGK HK C+ A+ P D PC E R C+ Sbjct: 224 LQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAE-PVGD--FPCGKEAP-ARLCEG 279 Query: 329 GTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTL 388 T C+ W GP GITNFDN FA+LTVFQCITMEGWTD+LY NDA G W W+YF+ L Sbjct: 280 DTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPL 339 Query: 389 IIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDID 448 IIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E +L GYL+WI +AE++ Sbjct: 340 IIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVM 399 Query: 449 PENEDEGMDEEKP----RNMSMPTSETESVNTENVAGGDIEGENCG-----ARLAHRISK 499 ED +E+ P + + S + ++ E G D + C AR + + K Sbjct: 400 LAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAEE--GEDRFADLCAVGSPFARASLKSGK 457 Query: 500 SKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTA 559 ++ S Y+RR + R R VK+ FYW+V+ +V LNTL +A HYNQP LT A Sbjct: 458 TESSSYFRRKEKMFRFFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFA 517 Query: 560 NKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVL 619 L LF EM LKMY LG ++YF S FN FD V+ G + E + K S GISVL Sbjct: 518 EFVFLGLFLTEMSLKMYGLGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVL 577 Query: 620 RCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF 679 R +RLLRIFK+T+YW+SL NLV SLLNS++SI SLL LLFLFI++F+LLGMQLFGG+FNF Sbjct: 578 RALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNF 637 Query: 680 DEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFIC 739 + +T + FD FP ++LTVFQILTGEDWN+VMY GI + GG S GM YFI+L + Sbjct: 638 QD-ETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIESQGGVS-KGMFSSFYFIVLTLF 695 Query: 740 GNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE-------------- 785 GNY LLNVFLAIAVDNLA+A+ LT +EE EE +KLA + E Sbjct: 696 GNYTLLNVFLAIAVDNLANAQELTK-DEEEMEEAANQKLALQKAKEVAEVSPMSAANISI 754 Query: 786 --KKQELVEKPAVGESKEEKIELKSITAD-----GESPPATKINMDDLQPNENEDKSPYP 838 ++Q + +V E + ++ L+++ A E P ++ + + K+ Sbjct: 755 AARQQNSAKARSVWEQRASQLRLQNLRASCEALYSEMDPEERLRFATTRHLRPDMKTHLD 814 Query: 839 NPETTGEEDEEEPEMPVGPRPRP 861 P E + PVG + RP Sbjct: 815 RPLVV-ELGRDGARGPVGGKARP 836 Score = 216 bits (550), Expect = 2e-55 Identities = 179/716 (25%), Positives = 322/716 (44%), Gaps = 113/716 (15%) Query: 64 LMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPR------ALLCLTLKNPIRRAC 117 L G G AT+ + + Q GK + + PR ++ CL+ N +RR C Sbjct: 1084 LTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFC 1143 Query: 118 ISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK 177 IV + FE++IL+ I + +ALA P D N+ L+ ++Y+F +FT E +K Sbjct: 1144 HYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPR--NNALKYLDYIFTGVFTFEMVIK 1201 Query: 178 VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR 237 +I GLL HP AY R+ WN+LDF IVV G A +K N +K+LR Sbjct: 1202 MIDLGLLLHPGAYFRDLWNILDF-IVVSGALVAFAFSGSKGKDINT---------IKSLR 1251 Query: 238 AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT 297 RVLRPL+ + +P L+ V + ++ ++ +L+I ++ + + I+A+I ++LF GK Sbjct: 1252 VLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFF-Y 1310 Query: 298 CYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVF 357 C ++ + E + Q W K ++DN +A+LT+F Sbjct: 1311 CTDESKELERDCRGQYLDYEKEEVEAQPRQ--------W---KKYDFHYDNVLWALLTLF 1359 Query: 358 QCITMEGWTDVLYWVNDAVGRDWP---------WIYFVTLIIIGSFFVLNLVLGVLSGEF 408 T EGW VL DA + I++V ++ FF +N+ + ++ F Sbjct: 1360 TVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITF 1419 Query: 409 SKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPT 468 ++ GD K+ + LE++ + +D+ A KP MP Sbjct: 1420 QEQ-------GD--KVMSECSLEKNERACIDFAISA---------------KPLTRYMP- 1454 Query: 469 SETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYW 528 +++ S ++ W V S F + Sbjct: 1455 ------------------------------QNRQSFQYKTW---------TFVVSPPFEY 1475 Query: 529 LVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLF 588 ++ ++ LNT+ + + Y+ P + N ++F+ E +LK+ + G+ YF + Sbjct: 1476 FIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAW 1535 Query: 589 NRFDCFVVCGGILETILVE-TKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNS 647 N FD V G I + ++ E + + + +S LR R R+ K+ R ++ L+ + + S Sbjct: 1536 NVFDFVTVLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQS 1595 Query: 648 VRSIASLLLLLFLFIIIFSLLGMQLFGG-KFNFDEMQTRRSTFDNFPQSLLTVFQILTGE 706 +++ + LL+ + I++++GMQ+FG + D R + F F Q+L+ +F+ TGE Sbjct: 1596 FKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGE 1655 Query: 707 DWNSVMYDGIMAYGGPSFPGMLVC------IYFI-ILFICGNYILLNVFLAIAVDN 755 W+ +M + C YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1656 AWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1710 Score = 127 bits (319), Expect = 1e-28 Identities = 160/728 (21%), Positives = 303/728 (41%), Gaps = 146/728 (20%) Query: 526 FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQ- 581 F ++++ + N + +A E + ++E D + +F E +K+ +LG Sbjct: 97 FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156 Query: 582 ---AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLS 638 +Y + +N D VV GIL T + + LR VR+LR K+ SL Sbjct: 157 HKGSYLRNGWNVMDFVVVLTGILATAGTD------FDLRTLRAVRVLRPLKLVSGIPSLQ 210 Query: 639 NLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF------------------- 679 ++ S++ ++ + + LLLF I++F+++G++ + GKF+ Sbjct: 211 VVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAEPVGDFPCGK 270 Query: 680 --------DEMQTRR---------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGP 722 + + R + FDN ++LTVFQ +T E W ++Y+ A G Sbjct: 271 EAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNT 330 Query: 723 SFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTA 782 +YFI L I G++ +LN+ L + A +E+ER + R Sbjct: 331 -----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERERVENRRAF 372 Query: 783 SPEKKQELVEKPAVG------ESKEEKIELKSITADGESP------PATKINMDDLQPNE 830 ++Q+ +E+ G +++E + + A+ +SP ATK + +DL E Sbjct: 373 LKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAE 432 Query: 831 NEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFR 890 ED VG P + LK E+S++F FR Sbjct: 433 EG-------------EDRFADLCAVGS---PFARASLKSGKT---ESSSYFR-RKEKMFR 472 Query: 891 LQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIAL 950 R+V F ++L + L+++ +A Q L++ + VF +F E++L Sbjct: 473 FFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTT-TLYFAEFVFLGLFLTEMSL 531 Query: 951 KMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRPLR 1007 KM YG L S+ R+ FN D V+ S+ I+ + + +LR LR+LR + Sbjct: 532 KM--YG--LGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFK 587 Query: 1008 AINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEA 1067 L+++V + ++++I +++ + L +FA +G+QLF G+ Sbjct: 588 VTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQF------------ 635 Query: 1068 ECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDS 1127 ++D E +FD AA++ +F + T E W ++Y I+S Sbjct: 636 -------NFQD-------------ETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIES 675 Query: 1128 HTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE--QEYKNCELDKN 1185 +++ S +FI+ + + ++N+F+ + E ++ + E N Sbjct: 676 QGGVSKGMFS-----SFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEMEEAAN 730 Query: 1186 QRQCVEYA 1193 Q+ ++ A Sbjct: 731 QKLALQKA 738 Score = 116 bits (290), Expect = 3e-25 Identities = 94/326 (28%), Positives = 163/326 (50%), Gaps = 24/326 (7%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936 + F+FS +N R RI F +IL I+ + I LA E P + + L Sbjct: 74 SLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDT 133 Query: 937 DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKI 996 + F IF E +K+ A G HKGS+ RN +N++D +VV +++ + ++ Sbjct: 134 EPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA---TAGTDFDLRT 190 Query: 997 LRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLY 1056 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ MFA IG++ + GK + Sbjct: 191 LRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFH 250 Query: 1057 -TCSDSSKQTEAECKGNYITYKDGEV---DHPIIQPRSWENSKF---DFDNVLAAMMALF 1109 C +S T+AE G++ K+ + W F +FDN+L A++ +F Sbjct: 251 KACFPNS--TDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVF 308 Query: 1110 TVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTF 1169 T EGW ++LY + D+ G +N+ ++FI III +FFM+N+ +G + F Sbjct: 309 QCITMEGWTDILYNTNDA----AGNTWNW-----LYFIPLIIIGSFFMLNLVLGVLSGEF 359 Query: 1170 QEQGEQ-EYKNCELDKNQRQCVEYAL 1194 ++ E+ E + L ++Q +E L Sbjct: 360 AKERERVENRRAFLKLRRQQQIEREL 385 Score = 115 bits (287), Expect = 6e-25 Identities = 76/297 (25%), Positives = 134/297 (45%), Gaps = 57/297 (19%) Query: 1215 VVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFK 1274 +V + F +++ ++ LNT+C+AM HY Q + +F GLF EM LK+ Sbjct: 478 MVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLG 537 Query: 1275 PKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVAD 1334 P+ YF ++N FD ++VGS+ ++ + P Sbjct: 538 PRSYFRSSFNCFDFGVIVGSVFEVVWAAIKP----------------------------- 568 Query: 1335 GFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFF 1394 S I+ R R++R+ K+ +R L+ + + S +++ + L+ + Sbjct: 569 -------GSSFGISVLRALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIV 621 Query: 1395 IYAVIGMQVF-GKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKC 1453 ++A++GMQ+F G+ D T NF TFP A+L +F+ TGE W +M + Sbjct: 622 VFALLGMQLFGGQFNFQDETP---TTNFDTFPAAILTVFQILTGEDWNAVMYHGI----- 673 Query: 1454 APESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1507 ES+ S F+ FYFI + + ++N+F+A+ +DN LT+D Sbjct: 674 --ESQGGVSK-------GMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 721 Score = 83.2 bits (204), Expect = 3e-15 Identities = 70/295 (23%), Positives = 130/295 (44%), Gaps = 66/295 (22%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N V L + D L+ + +F +F++E LK+IA+G+L Sbjct: 1472 PFEYFIMAMIALNTVVLMMKF---YDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVL 1528 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + + + ++ LR FR R Sbjct: 1529 ----NYFRDAWNVFDFVTVLGSITDILVTEIAETNNF---------INLSFLRLFRAARL 1575 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F Sbjct: 1576 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-------------- 1621 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 ++ +DD S +H NF F A++ +F+ T E Sbjct: 1622 GNIALDDDTSI-----------------------NRHN--NFRTFLQALMLLFRSATGEA 1656 Query: 365 WTDVLYWV--NDAV---------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ N A G D+ + YFV+ I + SF +LNL + V+ F Sbjct: 1657 WHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1711 Score = 56.2 bits (134), Expect = 3e-07 Identities = 64/323 (19%), Positives = 118/323 (36%), Gaps = 102/323 (31%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + G ++ F G+F E +K+IA F Sbjct: 97 FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156 Query: 1274 KPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVA 1333 Y + WN D ++V+ I+ A T+ + Sbjct: 157 HKGSYLRNGWNVMDFVVVLTGILATAGTDFD----------------------------- 187 Query: 1334 DGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLF 1393 + R RV+R +KL+S ++ +L + +K+ L + LL+ Sbjct: 188 -------------LRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAI 234 Query: 1394 FIYAVIGMQV----FGKIALNDTTEINRNN------------------------------ 1419 ++A+IG++ F K ++T+ Sbjct: 235 LMFAIIGLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGI 294 Query: 1420 -NFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYF 1478 NF A+L +F+C T E W DI+ N+ + G+++ YF Sbjct: 295 TNFDNILFAILTVFQCITMEGWTDILY---------------NTNDA---AGNTWNWLYF 336 Query: 1479 ISFYMLCAFLIINLFVAVIMDNF 1501 I ++ +F ++NL + V+ F Sbjct: 337 IPLIIIGSFFMLNLVLGVLSGEF 359 >gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo sapiens] Length = 2506 Score = 757 bits (1954), Expect = 0.0 Identities = 407/907 (44%), Positives = 566/907 (62%), Gaps = 91/907 (10%) Query: 790 LVEKPAVGESKEEKIELKSITADGESPPATK--INMDDLQPNENEDKSPYPNPETTGEED 847 +V P+ ++ K K + PPA +N +Q N+N + P P E +E+ Sbjct: 1145 IVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKEEEKKEE 1204 Query: 848 EEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLIL 907 EE+ GP+P MP S+ FI S+ N R CH I+N F IL Sbjct: 1205 EEDDRGEDGPKP--------------MPPYSSMFILSTTNPLRRLCHYILNLRYFEMCIL 1250 Query: 908 FFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRN 967 I +SSI+LAAEDPVQ + RN++L YFD VFT +FT E+ +KM G LH+G++ R+ Sbjct: 1251 MVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRD 1310 Query: 968 YFNILDLLVVSVSLISFGIQSSA----INVVKILRVLRVLRPLRAINRAKGLKHVVQCVF 1023 +NILD +VVS +L++F ++ IN +K LRVLRVLRPL+ I R LK V CV Sbjct: 1311 LWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVV 1370 Query: 1024 VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH 1083 +++ + NI+IV L F+FA + VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV Sbjct: 1371 NSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVK- 1429 Query: 1084 PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS 1143 + R W+ +F +DNVL A++ LFTVST EGWP++L S+D+ E++GP YR+E+S Sbjct: 1430 --ARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMS 1487 Query: 1144 IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI 1203 IF+++Y ++ FF +NIFV +I+TFQEQG++ + L+KN+R C+++A+ A+PL R++ Sbjct: 1488 IFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHM 1547 Query: 1204 PKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGL 1261 P+N+ QY++W V S FEY + +I LNTI L M+ YG S ++ A+ + N++FT L Sbjct: 1548 PQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSL 1607 Query: 1262 FTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSH 1321 F++E +LK++AF +YF DAWN FD + V+GSI DI +TE Sbjct: 1608 FSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITDILVTEFG----------------- 1650 Query: 1322 PPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQA 1381 N+ I+++F RLFR RL+KLL +G IR LLWTF++SF+A Sbjct: 1651 --------------------NNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKA 1690 Query: 1382 LPYVALLIVMLFFIYAVIGMQVFGKIALN--------DTTEINRNNNFQTFPQAVLLLFR 1433 LPYV LLI MLFFIYA+IGMQVFG I ++ D +I +NNF+TF QA++LLFR Sbjct: 1691 LPYVCLLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFR 1750 Query: 1434 CATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLF 1493 ATGEAW +IML+C+ GK C NS CG+ FA FYF+SF LC+FL++NLF Sbjct: 1751 SATGEAWHNIMLSCLSGKPC-----DKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLF 1805 Query: 1494 VAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFG 1553 VAVIMDNF+YLTRD SILGPHHLDE+ R+WAEYDP A GR+ +LD+ +LR + PPLG G Sbjct: 1806 VAVIMDNFEYLTRDSSILGPHHLDEYVRVWAEYDPAAWGRMPYLDMYQMLRHMSPPLGLG 1865 Query: 1554 KLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPF 1613 K CP RVA KRL+ M++P+ D TV FN+TL AL+RTAL IK +G GA+ Sbjct: 1866 KKCPARVAYKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKIAKG--------GADK-- 1915 Query: 1614 RPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1673 +Q + ELR + IW S K LD +V P ++TVGK YA +I EY+R+ K Sbjct: 1916 ------QQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQSK 1969 Query: 1674 KRKEQGL 1680 +K Q + Sbjct: 1970 AKKLQAM 1976 Score = 671 bits (1731), Expect = 0.0 Identities = 383/826 (46%), Positives = 507/826 (61%), Gaps = 63/826 (7%) Query: 18 SNYGSPRPA-HANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTV 76 + +G PA + + AAAG+ GA S Q G G + Sbjct: 2 ARFGDEMPARYGGGGSGAAAGVVVGSGGGRGAGGSRQG-----------GQPGAQRMYKQ 50 Query: 77 SSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLT 133 S QR R Y P +Q T R +L + N +R+ I EW PFE +IL T Sbjct: 51 SMAQRARTMALYNPIPVRQNCLTVNR---SLFLFSEDNVVRKYAKKITEWPPFEYMILAT 107 Query: 134 IFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN 193 I ANC+ LA+ P+DD + L+ E F+ IF EA +K+IA G FH +YLRN Sbjct: 108 IIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRN 167 Query: 194 GWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPS 253 GWN++DF++V+ G+ + + G FD++ LRA RVLRPL+LVSG+PS Sbjct: 168 GWNVMDFVVVLTGILATV----------------GTEFDLRTLRAVRVLRPLKLVSGIPS 211 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 LQVVL SI+KAM+PLL I LL+ F I+I+AIIGLE +MGK H TC+ +EG D+ E P Sbjct: 212 LQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCF-EEGTDDIQGES-P 269 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 +PC E R C NGT C+P W+GP +GIT FDN FA+LTVFQCITMEGWTD+LY N Sbjct: 270 APCGTEEP-ARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSN 328 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA G W W+YF+ LIIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E + Sbjct: 329 DASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERE 388 Query: 434 LKGYLDWITQAEDIDPENEDEGMDEEKP----RNMSMPTSETESVNTENVAGGDIEGENC 489 L GY++WI++AE++ ++ ++ P R ++ S+T+ +N E + + Sbjct: 389 LNGYMEWISKAEEVILAEDETDGEQRHPFDALRRTTIKKSKTDLLNPEEAEDQLADIASV 448 Query: 490 G---ARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHY 546 G AR + + +K + S ++ + R R R VK+ FYW V+ LV LNTL +A HY Sbjct: 449 GSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHY 508 Query: 547 NQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILV 606 NQP WL++ A L LF +EM +KMY LG + YF S FN FDC V+ G I E I Sbjct: 509 NQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWA 568 Query: 607 ETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFS 666 K + GISVLR +RLLRIFK+T+YW SL NLV SLLNS++SI SLL LLFLFI++F+ Sbjct: 569 VIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFA 628 Query: 667 LLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPG 726 LLGMQLFGG+FNFDE T + FD FP +++TVFQILTGEDWN VMYDGI + GG G Sbjct: 629 LLGMQLFGGQFNFDE-GTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQ-GG 686 Query: 727 MLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERK---------- 776 M+ IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EEEE +K Sbjct: 687 MVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEVA 746 Query: 777 -----KLARTASPEKKQELVEKPA--VGESKEEKIELKSITADGES 815 A + K+Q+ +KPA V E + ++ +++ A E+ Sbjct: 747 EVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREA 792 Score = 202 bits (513), Expect = 4e-51 Identities = 176/705 (24%), Positives = 317/705 (44%), Gaps = 120/705 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 + K+++ + + P ++ L+ NP+RR C I+ + FE+ IL+ I + + Sbjct: 1199 EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI 1258 Query: 140 ALAIYIPFPEDDSNATNSNLERV-EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198 ALA P NA +N+ R +Y+F +FT E +K+I GL+ H AY R+ WN+L Sbjct: 1259 ALAAEDPV---QPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNIL 1315 Query: 199 DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258 DFI+V L + +K N +K+LR RVLRPL+ + +P L+ V Sbjct: 1316 DFIVVSGALVAFAFTGNSKGKDINT---------IKSLRVLRVLRPLKTIKRLPKLKAVF 1366 Query: 259 NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK-MHKTCYNQEGIADVPAEDDPSPCA 317 + ++ ++ + +I ++ + + I+A++ ++LF GK H T ++E D Sbjct: 1367 DCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDC---------- 1416 Query: 318 LETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV- 376 G + V + K+ ++DN +A+LT+F T EGW VL DA Sbjct: 1417 --RGKYLLYEKNEVKARDREWKKYEF-HYDNVLWALLTLFTVSTGEGWPQVLKHSVDATF 1473 Query: 377 --------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQ 428 R I++V ++ FF +N+ + ++ F ++ GD K+ E+ Sbjct: 1474 ENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KMMEEY 1524 Query: 429 QLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGEN 488 LE++ + +D+ A KP MP Sbjct: 1525 SLEKNERACIDFAISA---------------KPLTRHMP--------------------- 1548 Query: 489 CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ 548 ++K S +R W V S F + ++ ++ LNT+ + + Y Sbjct: 1549 ----------QNKQSFQYRMWQ---------FVVSPPFEYTIMAMIALNTIVLMMKFYGA 1589 Query: 549 PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVET 608 N +LF+ E +LK+ + G+ YF +N FD V G I + ILV Sbjct: 1590 SVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITD-ILVTE 1648 Query: 609 KIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLL 668 + + +S LR R R+ K+ R ++ L+ + + S +++ + LL+ + I++++ Sbjct: 1649 FGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1708 Query: 669 GMQLFGG--------KFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAY 719 GMQ+FG + DE Q T + F F Q+L+ +F+ TGE W+++M + Sbjct: 1709 GMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGK 1768 Query: 720 GGPSFPGML--------VCIYFI-ILFICGNYILLNVFLAIAVDN 755 G+L YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1769 PCDKNSGILTRECGNEFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1812 Score = 145 bits (366), Expect = 4e-34 Identities = 179/784 (22%), Positives = 325/784 (41%), Gaps = 160/784 (20%) Query: 480 AGGDIEGENCGARLAHRISKSKFSRYWRRWNRF-CRRKCRAAVKS-------NV------ 525 AGG +G GA+ ++ S ++ +R +N R+ C +S NV Sbjct: 33 AGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAK 92 Query: 526 -------FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKM 575 F ++++ + N + +A E + + ++E D + +F E +K+ Sbjct: 93 KITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKI 152 Query: 576 YSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT 631 +LG +Y + +N D VV GIL T+ E + LR VR+LR K+ Sbjct: 153 IALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTE------FDLRTLRAVRVLRPLKLV 206 Query: 632 RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF-------DEMQT 684 SL ++ S++ ++ + + LLLF I+IF+++G++ + GKF+ D++Q Sbjct: 207 SGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQG 266 Query: 685 RR------------------------------STFDNFPQSLLTVFQILTGEDWNSVMYD 714 + FDN ++LTVFQ +T E W ++Y+ Sbjct: 267 ESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYN 326 Query: 715 GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE 774 A G +YFI L I G++ +LN+ L + A +E+E Sbjct: 327 SNDASGNT-----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERE 368 Query: 775 RKKLARTASPEKKQELVEKPAVGE----SKEEKIELKSITADGESP-PATKINMDDLQPN 829 R + R ++Q+ +E+ G SK E++ L DGE P + ++ Sbjct: 369 RVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDALRRTTIK-- 426 Query: 830 ENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRF 889 + K+ NPE ED+ VG P + +K + E S FF R Sbjct: 427 --KSKTDLLNPEEA--EDQLADIASVGS---PFARASIKSAKL---ENSTFF-HKKERRM 475 Query: 890 RLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIA 949 R R+V F +L + L+++ +A Q + + L+Y + +F +F E+ Sbjct: 476 RFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQ-PEWLSDFLYYAEFIFLGLFMSEMF 534 Query: 950 LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRPL 1006 +KM G + + FN D V+ S+ I+ + +LR LR+LR Sbjct: 535 IKMYGLGT----RPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIF 590 Query: 1007 RAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTE 1066 + L+++V + ++++I +++ + L +FA +G+QLF G+ + + + T Sbjct: 591 KVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQ-FNFDEGTPPT- 648 Query: 1067 AECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSID 1126 +FD AA+M +F + T E W E++Y I Sbjct: 649 ------------------------------NFDTFPAAIMTVFQILTGEDWNEVMYDGIK 678 Query: 1127 SHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEYK 1178 S +G + SI+FI+ + + ++N+F+ + +T EQ E+E Sbjct: 679 SQGGVQGGMV-----FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAA 733 Query: 1179 NCEL 1182 N +L Sbjct: 734 NQKL 737 Score = 114 bits (285), Expect = 1e-24 Identities = 96/331 (29%), Positives = 162/331 (48%), Gaps = 33/331 (9%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936 + F+FS +N R +I F +IL I+ + I LA E P + + L Sbjct: 77 SLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDT 136 Query: 937 DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI-SFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV ++ + G + ++ Sbjct: 137 EPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFD----LR 192 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ +FA IG++ + GK Sbjct: 193 TLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252 Query: 1056 YT------CSDSSKQTEAEC--KGNYITYKDGEVDHPIIQPRSWE---NSKFDFDNVLAA 1104 +T D ++ A C + T +G P WE N FDN+L A Sbjct: 253 HTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPY-----WEGPNNGITQFDNILFA 307 Query: 1105 MMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 1164 ++ +F T EGW +LLY S D+ G +N+ ++FI III +FFM+N+ +G Sbjct: 308 VLTVFQCITMEGWTDLLYNSNDA----SGNTWNW-----LYFIPLIIIGSFFMLNLVLGV 358 Query: 1165 VIVTFQEQGEQ-EYKNCELDKNQRQCVEYAL 1194 + F ++ E+ E + L ++Q +E L Sbjct: 359 LSGEFAKERERVENRRAFLKLRRQQQIEREL 389 Score = 104 bits (260), Expect = 8e-22 Identities = 74/316 (23%), Positives = 138/316 (43%), Gaps = 64/316 (20%) Query: 1195 KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL 1254 K R +R YI + +V + F + + L+ LNT+C+A+ HY Q + Sbjct: 471 KERRMRFYIRR---------MVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYA 521 Query: 1255 NMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPS 1314 +F GLF EM +K+ + YF ++N FD +++GSI ++ + P Sbjct: 522 EFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPG-------- 573 Query: 1315 MGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1374 + I+ R R++R+ K+ +R L+ + Sbjct: 574 ----------------------------TSFGISVLRALRLLRIFKVTKYWASLRNLVVS 605 Query: 1375 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1434 + S +++ + L+ + ++A++GMQ+FG + E NF TFP A++ +F+ Sbjct: 606 LLNSMKSIISLLFLLFLFIVVFALLGMQLFG--GQFNFDEGTPPTNFDTFPAAIMTVFQI 663 Query: 1435 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1494 TGE W ++M ++G G F++ YFI + + ++N+F+ Sbjct: 664 LTGEDWNEVMY-------------DGIKSQGGVQGGMVFSI-YFIVLTLFGNYTLLNVFL 709 Query: 1495 AVIMDNF---DYLTRD 1507 A+ +DN LT+D Sbjct: 710 AIAVDNLANAQELTKD 725 Score = 82.0 bits (201), Expect = 6e-15 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 62/297 (20%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N + L + S A + L +F +F++E LKV+A+G+L Sbjct: 1566 PFEYTIMAMIALNTIVLMMKF---YGASVAYENALRVFNIVFTSLFSLECVLKVMAFGIL 1622 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + G N + ++ LR FR R Sbjct: 1623 ----NYFRDAWNIFDFVTVLGSITDILVTEF----GNNFI-------NLSFLRLFRAARL 1667 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F GI Sbjct: 1668 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF---------GNIGI 1718 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 DV ED T H NF F A++ +F+ T E Sbjct: 1719 -DVEDEDSDEDEFQITEH---------------------NNFRTFFQALMLLFRSATGEA 1756 Query: 365 WTDVLY-------------WVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ + G ++ + YFV+ I + SF +LNL + V+ F Sbjct: 1757 WHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1813 Score = 53.5 bits (127), Expect = 2e-06 Identities = 69/324 (21%), Positives = 118/324 (36%), Gaps = 103/324 (31%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + ++ F G+F E +K+IA F Sbjct: 100 FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159 Query: 1274 KPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVA 1333 Y + WN D ++V+ I+ TE + Sbjct: 160 HKGSYLRNGWNVMDFVVVLTGILATVGTEFD----------------------------- 190 Query: 1334 DGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLF 1393 + R RV+R +KL+S ++ +L + +K+ L + LL+ Sbjct: 191 -------------LRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAI 237 Query: 1394 FIYAVIGMQVF-GKI-----------------ALNDTTEINR---------------NNN 1420 I+A+IG++ + GK A T E R NN Sbjct: 238 LIFAIIGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNG 297 Query: 1421 FQTFPQ---AVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFY 1477 F AVL +F+C T E W D++ NS + G+++ Y Sbjct: 298 ITQFDNILFAVLTVFQCITMEGWTDLLY---------------NSNDAS---GNTWNWLY 339 Query: 1478 FISFYMLCAFLIINLFVAVIMDNF 1501 FI ++ +F ++NL + V+ F Sbjct: 340 FIPLIIIGSFFMLNLVLGVLSGEF 363 >gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E subunit [Homo sapiens] Length = 2270 Score = 734 bits (1895), Expect = 0.0 Identities = 390/871 (44%), Positives = 545/871 (62%), Gaps = 73/871 (8%) Query: 833 DKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQ 892 D P E EDEEE E + + +E M S+ FIFS+ N R Sbjct: 1093 DGEASPLKEAEIREDEEEVEKKKQKKEK-------RETGKAMVPHSSMFIFSTTNPIRRA 1145 Query: 893 CHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKM 952 CH IVN F IL I SSI+LAAEDPV S RN +L YFD VFT +FT E+ +KM Sbjct: 1146 CHYIVNLRYFEMCILLVIAASSIALAAEDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKM 1205 Query: 953 TAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA-------INVVKILRVLRVLRP 1005 G L GS+ R+ +NILD +VV +L++F + ++ I +K LRVLRVLRP Sbjct: 1206 IDQGLILQDGSYFRDLWNILDFVVVVGALVAFALANALGTNKGRDIKTIKSLRVLRVLRP 1265 Query: 1006 LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT 1065 L+ I R LK V CV +++ + NI+IV L F+FA I VQLFKGK + C+DSSK T Sbjct: 1266 LKTIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKDT 1325 Query: 1066 EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI 1125 E EC GNY+ ++ +++ ++ R W+ +F +DN++ A++ LFTVST EGWP++L S+ Sbjct: 1326 EKECIGNYVDHEKNKME---VKGREWKRHEFHYDNIIWALLTLFTVSTGEGWPQVLQHSV 1382 Query: 1126 DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKN 1185 D ED+GP + R+E+SIF+++Y ++ FF +NIFV +I+TFQEQG++ + C L+KN Sbjct: 1383 DVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLEKN 1442 Query: 1186 QRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQ 1243 +R C+++A+ A+PL RY+P+N+H QY+VW+ V S FEY + +I LNT+ L M++Y Sbjct: 1443 ERACIDFAISAKPLTRYMPQNRHTFQYRVWHFVVSPSFEYTIMAMIALNTVVLMMKYYSA 1502 Query: 1244 SCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEV 1303 C +++A+ LN+ FT +F++E +LK+IAF +YF D WN FD + V+GSI +I +T+ Sbjct: 1503 PCTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEIILTD- 1561 Query: 1304 NPAEHTQCSPSMGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLS 1363 S +++F +LFR RL+KLL Sbjct: 1562 ---------------------------------SKLVNTSGFNMSFLKLFRAARLIKLLR 1588 Query: 1364 RGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQT 1423 +G IR LLWTF++SF+ALPYV LLI MLFFIYA+IGMQVFG I L++ + INR+NNF++ Sbjct: 1589 QGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLDEESHINRHNNFRS 1648 Query: 1424 FPQAVLLLFRCATGEAWQDIMLACMPGKKCAPE-SEPSNSTEGETPCGSSFAVFYFISFY 1482 F +++LLFR ATGEAWQ+IML+C+ K C P+ + PS E E CG+ A YF+SF Sbjct: 1649 FFGSLMLLFRSATGEAWQEIMLSCLGEKGCEPDTTAPSGQNENER-CGTDLAYVYFVSFI 1707 Query: 1483 MLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTL 1542 C+FL++NLFVAVIMDNF+YLTRD SILGPHHLDEF R+WAEYD A GRI + ++ + Sbjct: 1708 FFCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFVRVWAEYDRAACGRIHYTEMYEM 1767 Query: 1543 LRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSP 1602 L + PPLG GK CP +VA KRLV MNMP+ D TV F +TL AL+RTAL IK +G Sbjct: 1768 LTLMSPPLGLGKRCPSKVAYKRLVLMNMPVAEDMTVHFTSTLMALIRTALDIKIAKG--- 1824 Query: 1603 SEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYAT 1662 + +Q + EL+ IW S K+LD +VP ++TVGK YA Sbjct: 1825 -------------GADRQQLDSELQKETLAIWPHLSQKMLDLLVPMPKASDLTVGKIYAA 1871 Query: 1663 FLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1693 +I +Y+++ K +K++ + Q+NA Q Sbjct: 1872 MMIMDYYKQSKVKKQRQQL--EEQKNAPMFQ 1900 Score = 630 bits (1626), Expect = e-180 Identities = 359/754 (47%), Positives = 468/754 (62%), Gaps = 35/754 (4%) Query: 60 RQAKLMGSAGNATISTVSSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRA 116 RQ + ++G A + QR R Y P +Q T R +L N +R+ Sbjct: 25 RQGTPVPASGQAAAYKQTKAQRARTMALYNPIPVRQNCFTVNR---SLFIFGEDNIVRKY 81 Query: 117 CISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFL 176 +++W PFE +IL TI ANC+ LA+ PEDD + LE+ E F+ IF EA + Sbjct: 82 AKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGI 141 Query: 177 KVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKAL 236 K++A G +FH +YLRNGWN++DFI+V+ G+ AT N D++ L Sbjct: 142 KIVALGFIFHKGSYLRNGWNVMDFIVVLSGIL------ATAGTHFNT------HVDLRTL 189 Query: 237 RAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHK 296 RA RVLRPL+LVSG+PSLQ+VL SI+KAMVPLL I LL+ F I+++AIIGLE + GK+H+ Sbjct: 190 RAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHR 249 Query: 297 TCY-NQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLT 355 C+ N GI + D P PC ++ C G CK W GP GIT FDN FA+LT Sbjct: 250 ACFMNNSGILE--GFDPPHPCGVQG-----CPAGYECKD-WIGPNDGITQFDNILFAVLT 301 Query: 356 VFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKA 415 VFQCITMEGWT VLY NDA+G W W+YF+ LIIIGSFFVLNLVLGVLSGEF+KERE+ Sbjct: 302 VFQCITMEGWTTVLYNTNDALGATWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERERV 361 Query: 416 KARGDFQKLREKQQLEEDLKGYLDWITQAEDI--DPENEDEGMDE-EKPRNMSMPTSETE 472 + R F KLR +QQ+E +L GY WI +AE++ EN++ G E R ++ S TE Sbjct: 362 ENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTE 421 Query: 473 SVNTENVAGGDIEGENCGARLAHRISKSKFS---RYWRRWNRFCRRKCRAAVKSNVFYWL 529 ++ ++ ++ + G LA KS Y+R R R R VKS VFYW+ Sbjct: 422 AMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRISIRHMVKSQVFYWI 481 Query: 530 VIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFN 589 V+ LV LNT +A H+NQP WLT + A L LF EM LKMY +G + YF S FN Sbjct: 482 VLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRLYFHSSFN 541 Query: 590 RFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVR 649 FD V G I E + + + GISVLR +RLLRIFKIT+YW SL NLV SL++S++ Sbjct: 542 CFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSSMK 601 Query: 650 SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWN 709 SI SLL LLFLFI++F+LLGMQLFGG+FNF++ T + FD FP +++TVFQILTGEDWN Sbjct: 602 SIISLLFLLFLFIVVFALLGMQLFGGRFNFND-GTPSANFDTFPAAIMTVFQILTGEDWN 660 Query: 710 SVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEE 769 VMY+GI + GG S GM IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EE Sbjct: 661 EVMYNGIRSQGGVS-SGMWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEE 719 Query: 770 EEEKERKKLARTASPEKKQELVEKPAVGESKEEK 803 EE +K + A P++ + + Sbjct: 720 EEAFNQKHALQKAKEVSPMSAPNMPSIERDRRRR 753 Score = 220 bits (561), Expect = 1e-56 Identities = 185/707 (26%), Positives = 329/707 (46%), Gaps = 124/707 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 ++K+Q K +K+ + A P ++ + NPIRRAC IV + FE+ ILL I A+ + Sbjct: 1112 EKKKQ---KKEKRETGKAMVPHSSMFIFSTTNPIRRACHYIVNLRYFEMCILLVIAASSI 1168 Query: 140 ALAIYIPFPEDDSNATNSNLERV----EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGW 195 ALA +D TNS +V +Y+F +FT E +K+I GL+ +Y R+ W Sbjct: 1169 ALAA------EDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKMIDQGLILQDGSYFRDLW 1222 Query: 196 NLLDFIIVVVGLFSAILEQATKADGANALG-GKGAGF-DVKALRAFRVLRPLRLVSGVPS 253 N+LDF++VV L + L ANALG KG +K+LR RVLRPL+ + +P Sbjct: 1223 NILDFVVVVGALVAFAL--------ANALGTNKGRDIKTIKSLRVLRVLRPLKTIKRLPK 1274 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 L+ V + ++ ++ + +I ++ + I+A+I ++LF GK C + ++D Sbjct: 1275 LKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFF-YCTDS-------SKDTE 1326 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 C G+ + + G + +H ++DN +A+LT+F T EGW VL Sbjct: 1327 KEC---IGNYVDHEKNKMEVKGREWKRHEF-HYDNIIWALLTLFTVSTGEGWPQVLQHSV 1382 Query: 374 DAVGRD---------WPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKL 424 D D I++V ++ FF +N+ + ++ F ++ GD K+ Sbjct: 1383 DVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KM 1433 Query: 425 REKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDI 484 E+ LE++ + +D+ A KP MP Sbjct: 1434 MEECSLEKNERACIDFAISA---------------KPLTRYMP----------------- 1461 Query: 485 EGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASE 544 +++ + +R W+ V S F + ++ ++ LNT+ + + Sbjct: 1462 --------------QNRHTFQYRVWH---------FVVSPSFEYTIMAMIALNTVVLMMK 1498 Query: 545 HYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETI 604 +Y+ P N A +F+ E +LK+ + G YF +N FD V G I E I Sbjct: 1499 YYSAPCTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEII 1558 Query: 605 LVETKIMSPLG--ISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFI 662 L ++K+++ G +S L+ R R+ K+ R ++ L+ + + S +++ + LL+ + Sbjct: 1559 LTDSKLVNTSGFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLF 1618 Query: 663 IIFSLLGMQLFGG-KFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG- 720 I++++GMQ+FG K + + R + F +F SL+ +F+ TGE W +M + G Sbjct: 1619 FIYAIIGMQVFGNIKLDEESHINRHNNFRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGC 1678 Query: 721 -----GPSFPGM-------LVCIYFIILFICGNYILLNVFLAIAVDN 755 PS L +YF+ ++++LN+F+A+ +DN Sbjct: 1679 EPDTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMDN 1725 Score = 186 bits (473), Expect = 2e-46 Identities = 172/720 (23%), Positives = 305/720 (42%), Gaps = 163/720 (22%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILFYF 936 + FIF +N R ++++ F +IL I+ + I LA E P + + L Sbjct: 68 SLFIFGEDNIVRKYAKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKT 127 Query: 937 DIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVV-SVSLISFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV S L + G + ++ Sbjct: 128 EPYFIGIFCFEAGIKIVALGFIFHKGSYLRNGWNVMDFIVVLSGILATAGTHFNTHVDLR 187 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ MFA IG++ + GKL Sbjct: 188 TLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKL 247 Query: 1056 YTCSDSSKQTEAECKGNYITYKDG-EVDHPI--------IQPRSW---ENSKFDFDNVLA 1103 + C N +G + HP + + W + FDN+L Sbjct: 248 HRA----------CFMNNSGILEGFDPPHPCGVQGCPAGYECKDWIGPNDGITQFDNILF 297 Query: 1104 AMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVG 1163 A++ +F T EGW +LY + D+ G +N+ ++FI III +FF++N+ +G Sbjct: 298 AVLTVFQCITMEGWTTVLYNTNDA----LGATWNW-----LYFIPLIIIGSFFVLNLVLG 348 Query: 1164 ------------------FVIVTFQEQGEQEYKNCEL----------------------- 1182 F+ + Q+Q E+E Sbjct: 349 VLSGEFAKERERVENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALE 408 Query: 1183 -----------------DKNQRQCVEYALKARPLRRYIPKN---------QHQYK----- 1211 D + CV+ + PL R K+ +H+ + Sbjct: 409 VLRRATIKRSRTEAMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRIS 468 Query: 1212 VWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLI 1271 + ++V S F +++ L+ LNT C+A+ H+ Q + LF GLF +EM LK+ Sbjct: 469 IRHMVKSQVFYWIVLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMY 528 Query: 1272 AFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPP 1331 P+ YF ++N FD + VGSI ++ P Sbjct: 529 GMGPRLYFHSSFNCFDFGVTVGSIFEVVWAIFRPG------------------------- 563 Query: 1332 VADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVM 1391 + I+ R R++R+ K+ +R L+ + + S +++ + L+ + Sbjct: 564 -----------TSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFL 612 Query: 1392 LFFIYAVIGMQVF-GKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPG 1450 ++A++GMQ+F G+ ND T + NF TFP A++ +F+ TGE W ++M + Sbjct: 613 FIVVFALLGMQLFGGRFNFNDGTP---SANFDTFPAAIMTVFQILTGEDWNEVMYNGI-- 667 Query: 1451 KKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1507 ++G G ++ YFI + + ++N+F+A+ +DN LT+D Sbjct: 668 -----------RSQGGVSSG-MWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 715 Score = 135 bits (340), Expect = 4e-31 Identities = 154/731 (21%), Positives = 303/731 (41%), Gaps = 140/731 (19%) Query: 526 FYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKA---LLALFTAEMLLKMYSLGL-- 580 F ++++ + N + +A E + + T + K + +F E +K+ +LG Sbjct: 91 FEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGIKIVALGFIF 150 Query: 581 --QAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLS 638 +Y + +N D VV GIL T T + + + LR VR+LR K+ SL Sbjct: 151 HKGSYLRNGWNVMDFIVVLSGILAT--AGTHFNTHVDLRTLRAVRVLRPLKLVSGIPSLQ 208 Query: 639 NLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFN-------------FDEMQTR 685 ++ S++ ++ + + LLLF I++F+++G++ + GK + FD Sbjct: 209 IVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHRACFMNNSGILEGFDPPHPC 268 Query: 686 R--------------------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP 725 + FDN ++LTVFQ +T E W +V+Y+ A G Sbjct: 269 GVQGCPAGYECKDWIGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTNDALGAT--- 325 Query: 726 GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE 785 +YFI L I G++ +LN+ L + A +E+ER + R Sbjct: 326 --WNWLYFIPLIIIGSFFVLNLVLGVLSGEFA-------------KERERVENRRAFMKL 370 Query: 786 KKQELVEKPAVGE----SKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPE 841 ++Q+ +E+ G K E++ L + + + ++ + E + Sbjct: 371 RRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTEAMT------ 424 Query: 842 TTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTI 901 + +E + + PL+ +K V + R+ +V + Sbjct: 425 ---RDSSDEHCVDISSVGTPLARASIKSAKVD----GVSYFRHKERLLRISIRHMVKSQV 477 Query: 902 FTNLILFFILLSSISLAAEDPVQHTS--FRNHILFYFDIVFTTIFTIEIALKMTAYGAFL 959 F ++L + L++ +A V H + H+L+Y + +F +F +E++LKM G L Sbjct: 478 FYWIVLSLVALNTACVAI---VHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRL 534 Query: 960 HKGSFCRNYFNILD--LLVVSVSLISFGIQSSAINV-VKILRVLRVLRPLRAINRAKGLK 1016 + + FN D + V S+ + + I + + +LR LR+LR + L+ Sbjct: 535 ----YFHSSFNCFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLR 590 Query: 1017 HVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITY 1076 ++V + ++++I +++ + L +FA +G+QLF G+ + Sbjct: 591 NLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGRF-------------------NF 631 Query: 1077 KDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIY 1136 DG +FD AA+M +F + T E W E++Y I S ++ Sbjct: 632 NDG-------------TPSANFDTFPAAIMTVFQILTGEDWNEVMYNGIRSQGGVSSGMW 678 Query: 1137 NYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEYKNCELDKNQRQ 1188 + +I+FI+ + + ++N+F+ + +T EQ E+E NQ+ Sbjct: 679 S-----AIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEE------AFNQKH 727 Query: 1189 CVEYALKARPL 1199 ++ A + P+ Sbjct: 728 ALQKAKEVSPM 738 Score = 81.3 bits (199), Expect = 1e-14 Identities = 72/302 (23%), Positives = 131/302 (43%), Gaps = 74/302 (24%) Query: 126 FEIIILLTIFANCVALAI-YIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 FE I+ I N V L + Y P A L+ + F ++F++E LKVIA+G L Sbjct: 1480 FEYTIMAMIALNTVVLMMKYYSAPCTYELA----LKYLNIAFTMVFSLECVLKVIAFGFL 1535 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DFI V+ + IL + + + GF++ L+ FR R Sbjct: 1536 ----NYFRDTWNIFDFITVIGSITEIILTDSKLVNTS--------GFNMSFLKLFRAARL 1583 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F Sbjct: 1584 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-------------- 1629 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 ++ ++ E+ R NF +F +++ +F+ T E Sbjct: 1630 GNIKLDE-------ESHINRH------------------NNFRSFFGSLMLLFRSATGEA 1664 Query: 365 WTDVLYWV------------------NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 W +++ N+ G D ++YFV+ I SF +LNL + V+ Sbjct: 1665 WQEIMLSCLGEKGCEPDTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMD 1724 Query: 407 EF 408 F Sbjct: 1725 NF 1726 >gi|111378393 sodium channel, voltage-gated, type VII, alpha [Homo sapiens] Length = 1682 Score = 400 bits (1029), Expect = e-111 Identities = 402/1601 (25%), Positives = 705/1601 (44%), Gaps = 261/1601 (16%) Query: 103 ALLC-LTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLER 161 ++LC L+ N IRR I ++ F++ IL+++ +CV +++ +NL + Sbjct: 96 SILCTLSPFNCIRRTTIKVLVHPFFQLFILISVLIDCVFMSL-------------TNLPK 142 Query: 162 ----VEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK 217 +E L I+T E +K+ A G+ ++L + WN LDF + V F I+ + Sbjct: 143 WRPVLENTLLGIYTFEILVKLFARGVWAGSFSFLGDPWNWLDFSVTV---FEVIIRYSPL 199 Query: 218 ADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLF 277 + L+ R LR L+++ L+ ++ +I + L+ + +L LF Sbjct: 200 DF-------------IPTLQTARTLRILKIIPLNQGLKSLVGVLIHCLKQLIGVIILTLF 246 Query: 278 VIIIYAIIGLELFMGKMHKTCYN--QEGIADVPAEDDPSP-------------------- 315 + I+++IG+ LFMG + C+ QE + +P Sbjct: 247 FLSIFSLIGMGLFMGNLKHKCFRWPQENENETLHNRTGNPYYIRETENFYYLEGERYALL 306 Query: 316 CALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYW-VND 374 C T G QC G VC P G TNFD+F +A+ +F+ + + + +VLY + Sbjct: 307 CGNRTDAG-QCPEGYVCVKAGINPDQGFTNFDSFGWALFALFRLMAQD-YPEVLYHQILY 364 Query: 375 AVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREK--QQLEE 432 A G+ + I+FV + + SF++ +L LG+L+ + +E+++ G+ K E QQ + Sbjct: 365 ASGKVY-MIFFVVVSFLFSFYMASLFLGILAMAYEEEKQRV---GEISKKIEPKFQQTGK 420 Query: 433 DLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGAR 492 +L+ EG + ++ + + + + ++T+ D+ E+ R Sbjct: 421 ELQ------------------EGNETDEAKTIQIEMKKRSPISTDTSL--DVL-EDATLR 459 Query: 493 LAHRISKSK---------FSRYWRRWNRF-CRRKCRAAVKSNVFY----WLVIFLVFLNT 538 + KSK F++ + WN C K + V + +I + LN Sbjct: 460 HKEELEKSKKICPLYWYKFAKTFLIWNCSPCWLKLKEFVHRIIMAPFTDLFLIICIILNV 519 Query: 539 LTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCG 598 + EHY + + N + +FTAEM+ K+ ++ YF +N FD +V Sbjct: 520 CFLTLEHYPMSKQTNTLLNIGNLVFIGIFTAEMIFKIIAMHPYGYFQVGWNIFDSMIVFH 579 Query: 599 GILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLL 658 G++E L G+++LR R+LRIFK+ +YW + L+ SL NS ++ L+LLL Sbjct: 580 GLIELCLANVA-----GMALLRLFRMLRIFKLGKYWPTFQILMWSLSNSWVALKDLVLLL 634 Query: 659 FLFIIIFSLLGMQLFGGKFNFDEM--------QTRRSTFDNFPQSLLTVFQILTGEDWNS 710 F FI + GM+LFG N++E Q R +F S L VF+IL GE W Sbjct: 635 FTFIFFSAAFGMKLFGK--NYEEFVCHIDKDCQLPRWHMHDFFHSFLNVFRILCGE-WVE 691 Query: 711 VMYDGIMAYGGPSFPGMLVCI-YFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEE 769 ++D M G S+ CI +++++ + GN ++L +FLA+ V + + + +T+ + E Sbjct: 692 TLWD-CMEVAGQSW-----CIPFYLMVILIGNLLVLYLFLAL-VSSFSSCKDVTAEENNE 744 Query: 770 EEEKER--------------KKLARTASPEK------KQELVEKPAVGESKEEKIELKSI 809 + + K L +T + K + V++ + E + Sbjct: 745 AKNLQLAVARIKKGINYVLLKILCKTQNVPKDTMDHVNEVYVKEDISDHTLSELSNTQDF 804 Query: 810 TADGESPPATKINMDDLQPNENEDKSPYPN-----PETTGEEDEE-------EPEMPVGP 857 D E T+ N + NE++ P P+ P +GE D E + + G Sbjct: 805 LKDKEKSSGTEKNATE---NESQSLIPSPSVSETVPIASGESDIENLDNKEIQSKSGDGG 861 Query: 858 RPRPLSELHLKEKA---VPMPEASAFFIFSSNNR-------------------------- 888 + + E + + + E F ++ Sbjct: 862 SKEKIKQSSSSECSTVDIAISEEEEMFYGGERSKHLKNGCRRGSSLGQISGASKKGKIWQ 921 Query: 889 -FRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILF-YFDIVFTTIFTI 946 R C +IV + F I LLS+ +LA ED IL Y D++FT IF + Sbjct: 922 NIRKTCCKIVENNWFKCFIGLVTLLSTGTLAFEDIYMDQRKTIKILLEYADMIFTYIFIL 981 Query: 947 EIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPL 1006 E+ LK AYG K F ++ LD +VV V +S + +K L ++ LRPL Sbjct: 982 EMLLKWMAYG---FKAYFSNGWYR-LDFVVVIVFCLS--LIGKTREELKPLISMKFLRPL 1035 Query: 1007 RAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTE 1066 R +++ + +K VV+ + N+ +V ++ +F+ +GV LF G+ Y C D + + Sbjct: 1036 RVLSQFERMKVVVRALIKTTLPTLNVFLVCLMIWLIFSIMGVDLFAGRFYECIDPT--SG 1093 Query: 1067 AECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSID 1126 + + K + WEN+K +FDNV ++L V+TF GW ++ +ID Sbjct: 1094 ERFPSSEVMNKSRCESLLFNESMLWENAKMNFDNVGNGFLSLLQVATFNGWITIMNSAID 1153 Query: 1127 SHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQ-----GEQEYKNCE 1181 S + P + + + +FI +II F +++ + +I F + G + + Sbjct: 1154 SVAVNIQPHFEVNIYMYCYFINFIIFGVFLPLSMLITVIIDNFNKHKIKLGGSNIFITVK 1213 Query: 1182 LDKNQRQC--VEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239 K R+ + Y RP+ R P N+ Q ++ VV S F ++ VLI I + + Sbjct: 1214 QRKQYRRLKKLMYEDSQRPVPR--PLNKLQGFIFDVVTSQAFNVIVMVLICFQAIAMMID 1271 Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIA 1299 QS IA+ +N +F L+T+E ILKLIAF+ YF AWN FD ++V+ SI + Sbjct: 1272 TDVQSLQMSIALYWINSIFVMLYTMECILKLIAFR-CFYFTIAWNIFDFMVVIFSITGL- 1329 Query: 1300 ITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLV 1359 C P S PP V +L + R++ Sbjct: 1330 -----------CLPMTVGSYLVPPSLV------------------------QLILLSRII 1354 Query: 1360 KLLSRGEG---IRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEIN 1416 +L G+G L+ + S AL + LLI ++ FIYAV GM F + IN Sbjct: 1355 HMLRLGKGPKVFHNLMLPLMLSLPALLNIILLIFLVMFIYAVFGMYNFAYV--KKEAGIN 1412 Query: 1417 RNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGK--KCAPES-EPSNSTEGETPCGS-S 1472 +NF+TF ++L LF+ A W ++ A K C P+ P G+ CG+ S Sbjct: 1413 DVSNFETFGNSMLCLFQVAIFAGWDGMLDAIFNSKWSDCDPDKINPGTQVRGD--CGNPS 1470 Query: 1473 FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWS-ILGPHHLDEFKRIWAEYDPEAK 1531 +FYF+S+ ++ +I+N+++ V+M+ + ++ + L +F ++W +DP+ Sbjct: 1471 VGIFYFVSYILISWLIIVNMYIVVVMEFLNIASKKKNKTLSEDDFRKFFQVWKRFDPDRT 1530 Query: 1532 GRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL 1572 I + + PPL K P++ +L+++++P+ Sbjct: 1531 QYIDSSKLSDFAAALDPPLFMAK--PNK---GQLIALDLPM 1566 Score = 136 bits (342), Expect = 3e-31 Identities = 155/717 (21%), Positives = 283/717 (39%), Gaps = 179/717 (24%) Query: 877 ASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED-PVQHTSFRNHILFY 935 AS S N R +++ F IL +L+ + ++ + P N +L Sbjct: 95 ASILCTLSPFNCIRRTTIKVLVHPFFQLFILISVLIDCVFMSLTNLPKWRPVLENTLL-- 152 Query: 936 FDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVK 995 I+T EI +K+ A G + SF + +N LD SV++ I+ S ++ + Sbjct: 153 ------GIYTFEILVKLFARGVWAGSFSFLGDPWNWLDF---SVTVFEVIIRYSPLDFIP 203 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 L+ R LR L+ I +GLK +V + ++ + ++I+T +F+ IG+ LF G L Sbjct: 204 TLQTARTLRILKIIPLNQGLKSLVGVLIHCLKQLIGVIILTLFFLSIFSLIGMGLFMGNL 263 Query: 1056 -YTCSDSSKQTEAECKGN------YIT------YKDGEVDHPIIQPR------------- 1089 + C ++ E E N YI Y +GE + R Sbjct: 264 KHKCFRWPQENENETLHNRTGNPYYIRETENFYYLEGERYALLCGNRTDAGQCPEGYVCV 323 Query: 1090 ----SWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIF 1145 + + +FD+ A+ ALF + + +PE+LY I G +Y IF Sbjct: 324 KAGINPDQGFTNFDSFGWALFALFRLMA-QDYPEVLYHQI---LYASGKVY------MIF 373 Query: 1146 FIIYIIIIAFFMMNIFVGFVIVTFQEQGEQ--------------------------EYKN 1179 F++ + +F+M ++F+G + + ++E+ ++ E K Sbjct: 374 FVVVSFLFSFYMASLFLGILAMAYEEEKQRVGEISKKIEPKFQQTGKELQEGNETDEAKT 433 Query: 1180 CELDKNQRQCV--------------------EYALKARPLRRYIPKNQHQYKVW------ 1213 +++ +R + E + K PL Y K + +W Sbjct: 434 IQIEMKKRSPISTDTSLDVLEDATLRHKEELEKSKKICPLYWY--KFAKTFLIWNCSPCW 491 Query: 1214 --------YVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVE 1265 ++ + + + + + I+LN L ++HY S +NI N++F G+FT E Sbjct: 492 LKLKEFVHRIIMAPFTDLFLIICIILNVCFLTLEHYPMSKQTNTLLNIGNLVFIGIFTAE 551 Query: 1266 MILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLA 1325 MI K+IA P YF WN FD++IV ++++ + V Sbjct: 552 MIFKIIAMHPYGYFQVGWNIFDSMIVFHGLIELCLANV---------------------- 589 Query: 1326 VLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1385 + RLFR++R+ KL + L+W+ S+ AL + Sbjct: 590 -------------------AGMALLRLFRMLRIFKLGKYWPTFQILMWSLSNSWVALKDL 630 Query: 1386 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNN-----NFQTFPQAVLLLFRCATGEAW 1440 LL+ F A GM++FGK I+++ + F + L +FR GE W Sbjct: 631 VLLLFTFIFFSAAFGMKLFGKNYEEFVCHIDKDCQLPRWHMHDFFHSFLNVFRILCGE-W 689 Query: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVI 1497 + + CM G S+ + +++ ++ L++ LF+A++ Sbjct: 690 VETLWDCM------------------EVAGQSWCIPFYLMVILIGNLLVLYLFLALV 728 Score = 71.2 bits (173), Expect = 1e-11 Identities = 88/396 (22%), Positives = 161/396 (40%), Gaps = 97/396 (24%) Query: 74 STVSSTQRKRQQYGKPKKQGSTTATRP-PRALLCLTLKNPIRRACISIVEWKPFEIIILL 132 S + T ++R+QY + KK + RP PR L N ++ +V + F +I+++ Sbjct: 1206 SNIFITVKQRKQYRRLKKLMYEDSQRPVPRPL------NKLQGFIFDVVTSQAFNVIVMV 1259 Query: 133 TIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLR 192 I +A+ I + S + L + +F++++T+E LK+IA+ Y Sbjct: 1260 LICFQAIAMMIDT---DVQSLQMSIALYWINSIFVMLYTMECILKLIAFRCF-----YFT 1311 Query: 193 NGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVP 252 WN+ DF++V+ + L G+ + V+ + R++ LRL G Sbjct: 1312 IAWNIFDFMVVIFSITGLCLPMTV---GSYLVPPSL----VQLILLSRIIHMLRLGKGPK 1364 Query: 253 SLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDD 312 ++ ++ ++ LL+I LL+ V+ IYA+ G+ F + GI DV Sbjct: 1365 VFHNLMLPLMLSLPALLNIILLIFLVMFIYAVFGMYNF-----AYVKKEAGINDV----- 1414 Query: 313 PSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWV 372 +NF+ F +ML +FQ GW +L + Sbjct: 1415 -------------------------------SNFETFGNSMLCLFQVAIFAGWDGMLDAI 1443 Query: 373 ------------------------NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 N +VG YFV+ I+I ++N+ + V+ EF Sbjct: 1444 FNSKWSDCDPDKINPGTQVRGDCGNPSVG----IFYFVSYILISWLIIVNMYIVVVM-EF 1498 Query: 409 ----SKEREKAKARGDFQKLREK-QQLEEDLKGYLD 439 SK++ K + DF+K + ++ + D Y+D Sbjct: 1499 LNIASKKKNKTLSEDDFRKFFQVWKRFDPDRTQYID 1534 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.136 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,857,362 Number of Sequences: 37866 Number of extensions: 4120384 Number of successful extensions: 26612 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 122 Number of HSP's successfully gapped in prelim test: 265 Number of HSP's that attempted gapping in prelim test: 19931 Number of HSP's gapped (non-prelim): 3179 length of query: 2179 length of database: 18,247,518 effective HSP length: 118 effective length of query: 2061 effective length of database: 13,779,330 effective search space: 28399199130 effective search space used: 28399199130 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.