BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|193788538 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 15 [Homo sapiens] (2138 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|193788538 calcium channel, voltage-dependent, L type, alpha 1... 4279 0.0 gi|193788540 calcium channel, voltage-dependent, L type, alpha 1... 4263 0.0 gi|193788542 calcium channel, voltage-dependent, L type, alpha 1... 4259 0.0 gi|193788724 calcium channel, voltage-dependent, L type, alpha 1... 4252 0.0 gi|193794828 calcium channel, voltage-dependent, L type, alpha 1... 4252 0.0 gi|193788544 calcium channel, voltage-dependent, L type, alpha 1... 4251 0.0 gi|193788732 calcium channel, voltage-dependent, L type, alpha 1... 4248 0.0 gi|193788530 calcium channel, voltage-dependent, L type, alpha 1... 4248 0.0 gi|193788526 calcium channel, voltage-dependent, L type, alpha 1... 4247 0.0 gi|120433602 calcium channel, voltage-dependent, L type, alpha 1... 4244 0.0 gi|193788730 calcium channel, voltage-dependent, L type, alpha 1... 4242 0.0 gi|193788536 calcium channel, voltage-dependent, L type, alpha 1... 4242 0.0 gi|193794830 calcium channel, voltage-dependent, L type, alpha 1... 4241 0.0 gi|193788720 calcium channel, voltage-dependent, L type, alpha 1... 4234 0.0 gi|193788528 calcium channel, voltage-dependent, L type, alpha 1... 4232 0.0 gi|193788548 calcium channel, voltage-dependent, L type, alpha 1... 4227 0.0 gi|193788728 calcium channel, voltage-dependent, L type, alpha 1... 4219 0.0 gi|193788534 calcium channel, voltage-dependent, L type, alpha 1... 4215 0.0 gi|193788532 calcium channel, voltage-dependent, L type, alpha 1... 4199 0.0 gi|193794832 calcium channel, voltage-dependent, L type, alpha 1... 4196 0.0 gi|192807298 calcium channel, voltage-dependent, L type, alpha 1... 2747 0.0 gi|192807300 calcium channel, voltage-dependent, L type, alpha 1... 2746 0.0 gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D ... 2746 0.0 gi|110349767 calcium channel, voltage-dependent, L type, alpha 1... 2298 0.0 gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F... 2279 0.0 gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s... 776 0.0 gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 769 0.0 gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s... 767 0.0 gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E... 749 0.0 gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo s... 335 2e-91 >gi|193788538 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 15 [Homo sapiens] Length = 2138 Score = 4279 bits (11098), Expect = 0.0 Identities = 2138/2138 (100%), Positives = 2138/2138 (100%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788540 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 16 [Homo sapiens] Length = 2138 Score = 4263 bits (11057), Expect = 0.0 Identities = 2131/2138 (99%), Positives = 2133/2138 (99%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788542 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 17 [Homo sapiens] Length = 2138 Score = 4259 bits (11047), Expect = 0.0 Identities = 2126/2138 (99%), Positives = 2131/2138 (99%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788724 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 2 [Homo sapiens] Length = 2186 Score = 4252 bits (11028), Expect = 0.0 Identities = 2138/2186 (97%), Positives = 2138/2186 (97%), Gaps = 48/2186 (2%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL--------------------GNADYVF 940 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL GNADYVF Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 941 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1300 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1320 Query: 1301 SETN----------------------------PAEHTQCSPSMNAEENSRISITFFRLFR 1332 SETN PAEHTQCSPSMNAEENSRISITFFRLFR Sbjct: 1321 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1380 Query: 1333 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1392 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE Sbjct: 1381 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1440 Query: 1393 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1452 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA Sbjct: 1441 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1500 Query: 1453 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1512 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI Sbjct: 1501 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1560 Query: 1513 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1572 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI Sbjct: 1561 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1620 Query: 1573 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1632 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK Sbjct: 1621 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1680 Query: 1633 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1692 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE Sbjct: 1681 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1740 Query: 1693 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1752 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST Sbjct: 1741 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1800 Query: 1753 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1812 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS Sbjct: 1801 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1860 Query: 1813 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP 1872 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP Sbjct: 1861 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP 1920 Query: 1873 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV 1932 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV Sbjct: 1921 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV 1980 Query: 1933 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC 1992 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC Sbjct: 1981 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC 2040 Query: 1993 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD 2052 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD Sbjct: 2041 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD 2100 Query: 2053 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE 2112 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE Sbjct: 2101 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE 2160 Query: 2113 DAGCVRARGRPSEEELQDSRVYVSSL 2138 DAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2161 DAGCVRARGRPSEEELQDSRVYVSSL 2186 >gi|193794828 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 7 [Homo sapiens] Length = 2157 Score = 4252 bits (11027), Expect = 0.0 Identities = 2131/2157 (98%), Positives = 2133/2157 (98%), Gaps = 19/2157 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1561 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1620 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1621 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1680 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1681 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1740 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1741 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1800 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1801 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1860 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1861 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1920 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1921 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1980 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1981 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2040 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2041 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2100 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2157 >gi|193788544 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 19 [Homo sapiens] Length = 2135 Score = 4251 bits (11026), Expect = 0.0 Identities = 2128/2138 (99%), Positives = 2130/2138 (99%), Gaps = 3/2138 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIA AEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIA---AEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 357 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 358 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 417 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 418 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 477 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 478 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 537 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 538 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 597 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 598 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 657 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 658 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 717 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 718 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 777 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 778 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 837 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 838 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 897 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 898 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 957 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 958 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1017 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1018 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1077 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1078 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1137 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1138 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1197 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1198 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1257 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN Sbjct: 1258 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1317 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1318 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1377 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1378 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1437 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1438 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1497 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1498 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1557 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1558 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1617 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1618 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1677 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1678 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1737 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1738 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1797 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1798 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1857 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1858 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1917 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1918 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1977 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1978 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2037 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2038 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2097 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2098 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2135 >gi|193788732 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 5 [Homo sapiens] Length = 2166 Score = 4248 bits (11018), Expect = 0.0 Identities = 2131/2166 (98%), Positives = 2133/2166 (98%), Gaps = 28/2166 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---------------- 1304 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVV 1320 Query: 1305 ------------PAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1352 PAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT Sbjct: 1321 GSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWT 1380 Query: 1353 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1412 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC Sbjct: 1381 FIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRC 1440 Query: 1413 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1472 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV Sbjct: 1441 ATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFV 1500 Query: 1473 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1532 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK Sbjct: 1501 AVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGK 1560 Query: 1533 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1592 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI Sbjct: 1561 LCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKI 1620 Query: 1593 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ Sbjct: 1621 WKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1680 Query: 1653 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1712 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS Sbjct: 1681 AGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQS 1740 Query: 1713 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1772 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN Sbjct: 1741 DGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANN 1800 Query: 1773 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1832 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS Sbjct: 1801 TALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETS 1860 Query: 1833 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1892 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS Sbjct: 1861 QDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSAS 1920 Query: 1893 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1952 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF Sbjct: 1921 LGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPF 1980 Query: 1953 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2012 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR Sbjct: 1981 ATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVR 2040 Query: 2013 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2072 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE Sbjct: 2041 PVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIE 2100 Query: 2073 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2132 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR Sbjct: 2101 EMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSR 2160 Query: 2133 VYVSSL 2138 VYVSSL Sbjct: 2161 VYVSSL 2166 >gi|193788530 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 9 [Homo sapiens] Length = 2157 Score = 4248 bits (11017), Expect = 0.0 Identities = 2126/2157 (98%), Positives = 2131/2157 (98%), Gaps = 19/2157 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1561 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1620 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1621 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1680 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1681 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1740 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1741 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1800 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1801 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1860 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1861 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1920 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1921 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1980 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1981 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2040 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2041 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2100 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2157 >gi|193788526 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 6 [Homo sapiens] Length = 2158 Score = 4247 bits (11016), Expect = 0.0 Identities = 2126/2158 (98%), Positives = 2131/2158 (98%), Gaps = 20/2158 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL--------------------GNADYVF 940 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL GNADYVF Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 941 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1300 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ + Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAI 1320 Query: 1301 SETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 +E NPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1321 TEVNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1380 Query: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1381 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1440 Query: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1441 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1500 Query: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1501 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1560 Query: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1600 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL Sbjct: 1561 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1620 Query: 1601 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1660 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD Sbjct: 1621 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1680 Query: 1661 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1720 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ Sbjct: 1681 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1740 Query: 1721 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1780 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR Sbjct: 1741 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1800 Query: 1781 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1840 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK Sbjct: 1801 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1860 Query: 1841 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1900 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH Sbjct: 1861 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1920 Query: 1901 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1960 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG Sbjct: 1921 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1980 Query: 1961 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2020 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS Sbjct: 1981 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2040 Query: 2021 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2080 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN Sbjct: 2041 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2100 Query: 2081 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2158 >gi|120433602 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 18 [Homo sapiens] Length = 2138 Score = 4244 bits (11006), Expect = 0.0 Identities = 2119/2138 (99%), Positives = 2126/2138 (99%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193788730 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 4 [Homo sapiens] Length = 2173 Score = 4242 bits (11001), Expect = 0.0 Identities = 2126/2173 (97%), Positives = 2131/2173 (98%), Gaps = 35/2173 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSN-----------------------------------RCHSRESQAAM 1825 AIRVQEVAWKLSSN RCHSRESQAAM Sbjct: 1801 AIRVQEVAWKLSSNRERHVPMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAM 1860 Query: 1826 AGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKR 1885 AGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKR Sbjct: 1861 AGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKR 1920 Query: 1886 GFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSP 1945 GFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSP Sbjct: 1921 GFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSP 1980 Query: 1946 ASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGS 2005 ASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGS Sbjct: 1981 ASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGS 2040 Query: 2006 SAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELAD 2065 SAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELAD Sbjct: 2041 SAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELAD 2100 Query: 2066 ACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSE 2125 ACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSE Sbjct: 2101 ACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSE 2160 Query: 2126 EELQDSRVYVSSL 2138 EELQDSRVYVSSL Sbjct: 2161 EELQDSRVYVSSL 2173 >gi|193788536 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 14 [Homo sapiens] Length = 2138 Score = 4242 bits (11001), Expect = 0.0 Identities = 2116/2138 (98%), Positives = 2127/2138 (99%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYW+ DA+G + PW+YFV+L+I GSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 >gi|193794830 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 10 [Homo sapiens] Length = 2155 Score = 4241 bits (10998), Expect = 0.0 Identities = 2129/2158 (98%), Positives = 2130/2158 (98%), Gaps = 23/2158 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQC--------- 1311 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN H C Sbjct: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN---HYFCDAWNTFDAL 1317 Query: 1312 -----------SPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1360 + NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL Sbjct: 1318 IVVGSIVDIAITEVNNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQAL 1377 Query: 1361 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1420 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD Sbjct: 1378 PYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQD 1437 Query: 1421 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1480 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD Sbjct: 1438 IMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFD 1497 Query: 1481 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1540 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC Sbjct: 1498 YLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVAC 1557 Query: 1541 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1600 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL Sbjct: 1558 KRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKL 1617 Query: 1601 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1660 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD Sbjct: 1618 LDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHD 1677 Query: 1661 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1720 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ Sbjct: 1678 IGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQ 1737 Query: 1721 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1780 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR Sbjct: 1738 TFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPR 1797 Query: 1781 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1840 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK Sbjct: 1798 PAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVK 1857 Query: 1841 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1900 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH Sbjct: 1858 MNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFH 1917 Query: 1901 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1960 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG Sbjct: 1918 LECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPG 1977 Query: 1961 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2020 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS Sbjct: 1978 SRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPS 2037 Query: 2021 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2080 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN Sbjct: 2038 QAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADN 2097 Query: 2081 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2098 ILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2155 >gi|193788720 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 1 [Homo sapiens] Length = 2221 Score = 4234 bits (10982), Expect = 0.0 Identities = 2138/2221 (96%), Positives = 2138/2221 (96%), Gaps = 83/2221 (3%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL--------------------GNADYVF 940 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL GNADYVF Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF 960 Query: 941 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1000 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL Sbjct: 961 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL 1020 Query: 1001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1060 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD Sbjct: 1021 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD 1080 Query: 1061 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1120 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL Sbjct: 1081 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL 1140 Query: 1121 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1180 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC Sbjct: 1141 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC 1200 Query: 1181 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1240 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH Sbjct: 1201 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH 1260 Query: 1241 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1300 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL Sbjct: 1261 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL 1320 Query: 1301 SETN----------------------------PAEHTQCSPSMNAEENSRISITFFRLFR 1332 SETN PAEHTQCSPSMNAEENSRISITFFRLFR Sbjct: 1321 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR 1380 Query: 1333 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1392 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE Sbjct: 1381 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE 1440 Query: 1393 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1452 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA Sbjct: 1441 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA 1500 Query: 1453 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1512 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI Sbjct: 1501 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI 1560 Query: 1513 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1572 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI Sbjct: 1561 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI 1620 Query: 1573 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1632 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK Sbjct: 1621 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK 1680 Query: 1633 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1692 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE Sbjct: 1681 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE 1740 Query: 1693 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1752 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST Sbjct: 1741 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST 1800 Query: 1753 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1812 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS Sbjct: 1801 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS 1860 Query: 1813 SN-----------------------------------RCHSRESQAAMAGQEETSQDETY 1837 SN RCHSRESQAAMAGQEETSQDETY Sbjct: 1861 SNRERHVPMCEDLELRRDSGSAGTQAHCLLLRKANPSRCHSRESQAAMAGQEETSQDETY 1920 Query: 1838 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA 1897 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA Sbjct: 1921 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA 1980 Query: 1898 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA 1957 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA Sbjct: 1981 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA 2040 Query: 1958 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM 2017 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM Sbjct: 2041 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM 2100 Query: 2018 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA 2077 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA Sbjct: 2101 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA 2160 Query: 2078 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS 2137 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS Sbjct: 2161 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS 2220 Query: 2138 L 2138 L Sbjct: 2221 L 2221 >gi|193788528 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 8 [Homo sapiens] Length = 2157 Score = 4232 bits (10976), Expect = 0.0 Identities = 2119/2157 (98%), Positives = 2126/2157 (98%), Gaps = 19/2157 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSMNAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN 1320 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1561 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1620 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1621 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1680 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1681 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1740 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1741 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1800 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1801 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1860 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1861 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1920 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1921 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1980 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1981 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2040 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2041 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2100 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2101 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2157 >gi|193788548 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 20 [Homo sapiens] Length = 2127 Score = 4227 bits (10962), Expect = 0.0 Identities = 2115/2138 (98%), Positives = 2120/2138 (99%), Gaps = 11/2138 (0%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E N NAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN-----------NAEEN 1309 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1310 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1369 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1370 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1429 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1430 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1489 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1490 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1549 Query: 1561 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1620 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA Sbjct: 1550 TLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYA 1609 Query: 1621 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1680 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD Sbjct: 1610 TFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELD 1669 Query: 1681 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1740 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT Sbjct: 1670 KAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDT 1729 Query: 1741 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1800 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP Sbjct: 1730 ESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSP 1789 Query: 1801 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS Sbjct: 1790 AIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1849 Query: 1861 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1920 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL Sbjct: 1850 YQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVL 1909 Query: 1921 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1980 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS Sbjct: 1910 PLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESS 1969 Query: 1981 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2040 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV Sbjct: 1970 EKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAV 2029 Query: 2041 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2100 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC Sbjct: 2030 LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNC 2089 Query: 2101 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2090 RDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2127 >gi|193788728 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 3 [Homo sapiens] Length = 2179 Score = 4219 bits (10943), Expect = 0.0 Identities = 2119/2179 (97%), Positives = 2126/2179 (97%), Gaps = 41/2179 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSM----- 1315 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NPAEHTQCSPSM Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCS 1320 Query: 1316 -----------------NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1358 NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ Sbjct: 1321 HPPLAVLTAPPVADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQ 1380 Query: 1359 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1418 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW Sbjct: 1381 ALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAW 1440 Query: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN Sbjct: 1441 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1500 Query: 1479 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1538 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV Sbjct: 1501 FDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRV 1560 Query: 1539 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE-------------------GNLE 1579 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE GNLE Sbjct: 1561 ACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLE 1620 Query: 1580 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL Sbjct: 1621 QANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGL 1680 Query: 1640 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1699 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA Sbjct: 1681 VGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRA 1740 Query: 1700 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1759 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS Sbjct: 1741 GGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYS 1800 Query: 1760 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1819 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR Sbjct: 1801 STGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSR 1860 Query: 1820 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1879 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI Sbjct: 1861 ESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDI 1920 Query: 1880 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1939 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL Sbjct: 1921 RQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLL 1980 Query: 1940 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 1999 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT Sbjct: 1981 QRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETT 2040 Query: 2000 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2059 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT Sbjct: 2041 PGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVT 2100 Query: 2060 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2119 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA Sbjct: 2101 TQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRA 2160 Query: 2120 RGRPSEEELQDSRVYVSSL 2138 RGRPSEEELQDSRVYVSSL Sbjct: 2161 RGRPSEEELQDSRVYVSSL 2179 >gi|193788534 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 12 [Homo sapiens] Length = 2146 Score = 4215 bits (10932), Expect = 0.0 Identities = 2115/2157 (98%), Positives = 2120/2157 (98%), Gaps = 30/2157 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E N NAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN-----------NAEEN 1309 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1310 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1369 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1370 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1429 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1430 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1489 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1490 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1549 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1550 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1609 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1610 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1669 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1670 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1729 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1730 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1789 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1790 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1849 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1850 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1909 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1910 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1969 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1970 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2029 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2030 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2089 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2090 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2146 >gi|193788532 calcium channel, voltage-dependent, L type, alpha 1C subunit isoform 11 [Homo sapiens] Length = 2146 Score = 4199 bits (10891), Expect = 0.0 Identities = 2108/2157 (97%), Positives = 2115/2157 (98%), Gaps = 30/2157 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E N NAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVN-----------NAEEN 1309 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1310 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1369 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1370 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1429 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1430 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1489 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1490 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1549 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1550 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1609 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1610 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1669 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1670 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1729 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1730 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1789 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1790 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1849 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1850 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1909 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1910 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1969 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1970 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2029 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2030 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2089 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2090 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2146 >gi|193794832 calcium channel, voltage-dependent, L type, alpha 1C subunit isoforom 13 [Homo sapiens] Length = 2144 Score = 4196 bits (10883), Expect = 0.0 Identities = 2107/2157 (97%), Positives = 2114/2157 (98%), Gaps = 32/2157 (1%) Query: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR Sbjct: 1 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR 60 Query: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI Sbjct: 61 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI 120 Query: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA Sbjct: 121 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA 180 Query: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR Sbjct: 181 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR 240 Query: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN Sbjct: 241 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN 300 Query: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI Sbjct: 301 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI 360 Query: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD Sbjct: 361 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD 420 Query: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA Sbjct: 421 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA 480 Query: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT Sbjct: 481 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT 540 Query: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI Sbjct: 541 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI 600 Query: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL Sbjct: 601 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL 660 Query: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG Sbjct: 661 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG 720 Query: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR Sbjct: 721 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR 780 Query: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP Sbjct: 781 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP 840 Query: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT Sbjct: 841 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT 900 Query: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLH 960 IFTNLILFFILLSSISLAAEDPVQHTSFRNHIL D VFT+IFT+EI LKMTAYGAFLH Sbjct: 901 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH 960 Query: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ Sbjct: 961 KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ 1020 Query: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE Sbjct: 1021 CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE 1080 Query: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV Sbjct: 1081 VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRV 1140 Query: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR Sbjct: 1141 EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR 1200 Query: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG Sbjct: 1201 RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG 1260 Query: 1261 LFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEEN 1320 LFTVEMILKLIAFKPK YF D WN FD LIV+GSI+D+ ++E NAEEN Sbjct: 1261 LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITE-------------NAEEN 1307 Query: 1321 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1380 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ Sbjct: 1308 SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ 1367 Query: 1381 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1440 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS Sbjct: 1368 VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS 1427 Query: 1441 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1500 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI Sbjct: 1428 TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI 1487 Query: 1501 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1560 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA Sbjct: 1488 WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA 1547 Query: 1561 TLFALVRTALRIKTE-------------------GNLEQANEELRAIIKKIWKRTSMKLL 1601 TLFALVRTALRIKTE GNLEQANEELRAIIKKIWKRTSMKLL Sbjct: 1548 TLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLL 1607 Query: 1602 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1661 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI Sbjct: 1608 DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI 1667 Query: 1662 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1721 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT Sbjct: 1668 GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT 1727 Query: 1722 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1781 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP Sbjct: 1728 FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRP 1787 Query: 1782 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1841 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM Sbjct: 1788 AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKM 1847 Query: 1842 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1901 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL Sbjct: 1848 NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL 1907 Query: 1902 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1961 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS Sbjct: 1908 ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS 1967 Query: 1962 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2021 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ Sbjct: 1968 RGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQ 2027 Query: 2022 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2081 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI Sbjct: 2028 AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI 2087 Query: 2082 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL Sbjct: 2088 LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2144 >gi|192807298 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform c [Homo sapiens] Length = 2137 Score = 2748 bits (7122), Expect = 0.0 Identities = 1457/2156 (67%), Positives = 1659/2156 (76%), Gaps = 136/2156 (6%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYW+NDA+G + PW+YFV+L+I GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN--CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524 PTSETESVNTENV+G EGEN C L ISKSK SR WRRWNRF RR+CRAAVKS Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSV 523 Query: 525 VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584 FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LLALFT EML+KMYSLGLQAYF Sbjct: 524 TFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYF 583 Query: 585 VSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASL 644 VSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRLLRIFK+TR+W SLSNLVASL Sbjct: 584 VSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASL 643 Query: 645 LNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILT 704 LNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT+RSTFDNFPQ+LLTVFQILT Sbjct: 644 LNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILT 703 Query: 705 GEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764 GEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYILLNVFLAIAVDNLADAESL + Sbjct: 704 GEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNT 763 Query: 765 AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMD 824 AQKEE EEKERKK+AR S E K+ KP V + K+ +D Sbjct: 764 AQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD---------------NKVTID 806 Query: 825 DLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASA 879 D + E+EDK PYP E EE+E+EPE+P GPRPR +SEL++KEK P+PE SA Sbjct: 807 DYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSA 865 Query: 880 FFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYV 939 FFI S N R+ CH+++N IFTNLIL FI+LSS +LAAEDP++ SFRN ILG DY Sbjct: 866 FFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYA 925 Query: 940 FTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRV 999 FT+IFT+EI+LKMT +GAFLHKG+FCRNYFN+LD+LVV VSL+SFGIQSSAI+VVKILRV Sbjct: 926 FTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRV 985 Query: 1000 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS 1059 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Y C+ Sbjct: 986 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCT 1045 Query: 1060 DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE 1119 D +K EC+G +I YKDG+VD P+++ R W+NS F+FDNVL+AMMALFTVSTFEGWP Sbjct: 1046 DEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPA 1105 Query: 1120 LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN 1179 LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMNIFVGFVIVTFQEQGE+EYKN Sbjct: 1106 LLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKN 1165 Query: 1180 CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239 CELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ FEY+MFVLI+LNT+CLAMQ Sbjct: 1166 CELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQ 1225 Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVI 1299 HY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPKGYFSD WN FD LIVIGSIIDV Sbjct: 1226 HYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVA 1285 Query: 1300 LSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQA 1359 LSE + N+EE++RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQA Sbjct: 1286 LSEAD-----------NSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQA 1334 Query: 1360 LPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQ 1419 LPYVALLI MLFFIYAVIGMQ+FGK+A+ D +INRNNNFQTFPQAVLLLFRCATGEAWQ Sbjct: 1335 LPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQ 1394 Query: 1420 DIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF 1479 +IMLAC+PGK C PES+ + E CGS+FA+ YFISFYMLCAFLIINLFVAVIMDNF Sbjct: 1395 EIMLACLPGKLCDPESDYNPGE--EYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNF 1452 Query: 1480 DYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVA 1539 DYLTRDWSILGPHHLDEFKRIW+EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVA Sbjct: 1453 DYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVA 1512 Query: 1540 CKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMK 1599 CKRLV+MNMPLNSDGTVMFNATLFALVRTAL+IKTEGNLEQANEELRA+IKKIWK+TSMK Sbjct: 1513 CKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMK 1572 Query: 1600 LLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGK-PSQRNALSLQAGLRTL 1658 LLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKFKKRKEQGLVGK P++ ++LQAGLRTL Sbjct: 1573 LLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTL 1632 Query: 1659 HDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAF 1718 HDIGPEIRRAIS DL +E E EDD+F+R G L GNHV++ SD R + Sbjct: 1633 HDIGPEIRRAISCDLQDDE------PEETKREEEDDVFKRNGALLGNHVNHVNSDRRDSL 1686 Query: 1719 PQTFTTQRPLHINKAG-SSQGDTESPSHEKLVDST-FTPSSYSS------TGSNANINNA 1770 QT TT RPLH+ + DTE P +S +++S T +NAN+NNA Sbjct: 1687 QQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNANLNNA 1746 Query: 1771 NNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEE 1830 N + RP+ + GH S+ H RE Q + + Sbjct: 1747 NMSKAAHGKRPSIGNLEHVSENGH-----------------HSSHKHDREPQRRSSVKRS 1789 Query: 1831 TSQDETYEVKMNHDTE---------ACSEPSLLSTEMLSYQDD----------------- 1864 S DE D E E S+E Y+DD Sbjct: 1790 DSGDEQLPTICREDPEIHGYFRDPHCLGEQEYFSSEE-CYEDDSSPTWSRQNYGYYSRYP 1848 Query: 1865 ------------ENRQLTLPEEDK---RDIRQSPKRGFL-RSASLGRRASFHLECLKRQK 1908 + Q L ++D D R+SP+R L + + RR+SF+ ECL+RQ Sbjct: 1849 GRNIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQS 1908 Query: 1909 DR-----GGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRG 1963 + +T LPLHL+ Q +AVAGL + +SP+ R +ATPPATP R Sbjct: 1909 SQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYRD 1968 Query: 1964 WPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAG 2023 W P P +++E E+ +++N S PS+H SW P + R P SL VPS Sbjct: 1969 WTPCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTDEP----DISYRTFTPASLTVPSSFR 2024 Query: 2024 APGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILS 2083 SA SLVEAVLISEGLG++A+DPKF+ T E+ADACD+TI+EMESAA +L+ Sbjct: 2025 NKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLLN 2084 Query: 2084 GGAPQSPNGALLPFVNCRDAG-QDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 G NG + P + +D QD G D R EE+L D + +++L Sbjct: 2085 GNVRPRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGR---DEEDLADEMICITTL 2137 >gi|192807300 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform b [Homo sapiens] Length = 2161 Score = 2746 bits (7119), Expect = 0.0 Identities = 1457/2157 (67%), Positives = 1664/2157 (77%), Gaps = 114/2157 (5%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYW+NDA+G + PW+YFV+L+I GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN--CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSN 524 PTSETESVNTENV+G EGEN C L ISKSK SR WRRWNRF RR+CRAAVKS Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLCQAISKSKLSRRWRRWNRFNRRRCRAAVKSV 523 Query: 525 VFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYF 584 FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LLALFT EML+KMYSLGLQAYF Sbjct: 524 TFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQAYF 583 Query: 585 VSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASL 644 VSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRLLRIFK+TR+W SLSNLVASL Sbjct: 584 VSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLVASL 643 Query: 645 LNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILT 704 LNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT+RSTFDNFPQ+LLTVFQILT Sbjct: 644 LNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQILT 703 Query: 705 GEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764 GEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYILLNVFLAIAVDNLADAESL + Sbjct: 704 GEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAESLNT 763 Query: 765 AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMD 824 AQKEE EEKERKK+AR S E K+ KP V + K+ +D Sbjct: 764 AQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD---------------NKVTID 806 Query: 825 DLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASA 879 D + E+EDK PYP E EE+E+EPE+P GPRPR +SEL++KEK P+PE SA Sbjct: 807 DYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSA 865 Query: 880 FFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYV 939 FFI S N R+ CH+++N IFTNLIL FI+LSS +LAAEDP++ SFRN ILG DY Sbjct: 866 FFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYA 925 Query: 940 FTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRV 999 FT+IFT+EI+LKMT +GAFLHKG+FCRNYFN+LD+LVV VSL+SFGIQSSAI+VVKILRV Sbjct: 926 FTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRV 985 Query: 1000 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCS 1059 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Y C+ Sbjct: 986 LRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCT 1045 Query: 1060 DSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPE 1119 D +K EC+G +I YKDG+VD P+++ R W+NS F+FDNVL+AMMALFTVSTFEGWP Sbjct: 1046 DEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPA 1105 Query: 1120 LLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKN 1179 LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMNIFVGFVIVTFQEQGE+EYKN Sbjct: 1106 LLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKN 1165 Query: 1180 CELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQ 1239 CELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ FEY+MFVLI+LNT+CLAMQ Sbjct: 1166 CELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQ 1225 Query: 1240 HYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVI 1299 HY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPKGYFSD WN FD LIVIGSIIDV Sbjct: 1226 HYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVA 1285 Query: 1300 LSETNPAEH----TQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIK 1355 LSE +P E + N+EE++RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIK Sbjct: 1286 LSEADPTESENVPVPTATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIK 1345 Query: 1356 SFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATG 1415 SFQALPYVALLI MLFFIYAVIGMQ+FGK+A+ D +INRNNNFQTFPQAVLLLFRCATG Sbjct: 1346 SFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATG 1405 Query: 1416 EAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVI 1475 EAWQ+IMLAC+PGK C PES+ + E CGS+FA+ YFISFYMLCAFLIINLFVAVI Sbjct: 1406 EAWQEIMLACLPGKLCDPESDYNPGE--EYTCGSNFAIVYFISFYMLCAFLIINLFVAVI 1463 Query: 1476 MDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCP 1535 MDNFDYLTRDWSILGPHHLDEFKRIW+EYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCP Sbjct: 1464 MDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCP 1523 Query: 1536 HRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKR 1595 HRVACKRLV+MNMPLNSDGTVMFNATLFALVRTAL+IKTEGNLEQANEELRA+IKKIWK+ Sbjct: 1524 HRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKK 1583 Query: 1596 TSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGK-PSQRNALSLQAG 1654 TSMKLLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKFKKRKEQGLVGK P++ ++LQAG Sbjct: 1584 TSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAG 1643 Query: 1655 LRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDG 1714 LRTLHDIGPEIRRAIS DL +E E EDD+F+R G L GNHV++ SD Sbjct: 1644 LRTLHDIGPEIRRAISCDLQDDE------PEETKREEEDDVFKRNGALLGNHVNHVNSDR 1697 Query: 1715 RSAFPQTFTTQRPLHINKAG-SSQGDTESPSHEKLVDST-FTPSSYSS------TGSNAN 1766 R + QT TT RPLH+ + DTE P +S +++S T +NAN Sbjct: 1698 RDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPTSTNAN 1757 Query: 1767 INNANNTALGRLPRPA----GYPSTVSTVEGHGPPLSPAIR--VQEVAWKLSSNRCHSRE 1820 +NNAN + RP+ + S H P R V+ + + R S + Sbjct: 1758 LNNANMSKAAHGKRPSIGNLEHVSENGHHSSHKHDREPQRRSSVKRTRYYETYIRSDSGD 1817 Query: 1821 SQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDD---------------- 1864 Q +E+ + D E S+E Y+DD Sbjct: 1818 EQLPTICREDPEIHGYF-----RDPHCLGEQEYFSSEE-CYEDDSSPTWSRQNYGYYSRY 1871 Query: 1865 -------------ENRQLTLPEEDK---RDIRQSPKRGFL-RSASLGRRASFHLECLKRQ 1907 + Q L ++D D R+SP+R L + + RR+SF+ ECL+RQ Sbjct: 1872 PGRNIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLLPPTPASHRRSSFNFECLRRQ 1931 Query: 1908 KDR-----GGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSR 1962 + +T LPLHL+ Q +AVAGL + +SP+ R +ATPPATP R Sbjct: 1932 SSQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQKYSPSHSTRSWATPPATPPYR 1991 Query: 1963 GWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQA 2022 W P P +++E E+ +++N S PS+H SW P + R P SL VPS Sbjct: 1992 DWTPCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTDEP----DISYRTFTPASLTVPSSF 2047 Query: 2023 GAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNIL 2082 SA SLVEAVLISEGLG++A+DPKF+ T E+ADACD+TI+EMESAA +L Sbjct: 2048 RNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTIDEMESAASTLL 2107 Query: 2083 SGGAPQSPNGALLPFVNCRDAG-QDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL 2138 +G NG + P + +D QD G D R EE+L D + +++L Sbjct: 2108 NGNVRPRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGR---DEEDLADEMICITTL 2161 >gi|4502527 calcium channel, voltage-dependent, L type, alpha 1D subunit isoform a [Homo sapiens] Length = 2181 Score = 2746 bits (7119), Expect = 0.0 Identities = 1461/2177 (67%), Positives = 1668/2177 (76%), Gaps = 134/2177 (6%) Query: 50 LSWQAAIDAARQAKLMGSAGNATISTVSS-TQRKRQQYGKPKKQGSTTATRPPRALLCLT 108 LSWQAAIDAARQAK + + V S +QRKRQQY K KKQG+++ +RP RAL CL+ Sbjct: 51 LSWQAAIDAARQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLS 110 Query: 109 LKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLI 168 L NPIRRACISIVEWKPF+I ILL IFANCVALAIYIPFPEDDSN+TN NLE+VEY FLI Sbjct: 111 LNNPIRRACISIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLI 170 Query: 169 IFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATK-ADGANALGGK 227 IFTVE FLK+IAYGLL HPNAY+RNGWNLLDF+IV+VGLFS ILEQ TK +G N GK Sbjct: 171 IFTVETFLKIIAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGK 230 Query: 228 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 287 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL Sbjct: 231 SGGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL 290 Query: 288 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNF 346 ELF+GKMHKTC+ + +D+ AE+DP+PCA +G+GRQC NGT C+ GW GP GITNF Sbjct: 291 ELFIGKMHKTCFFAD--SDIVAEEDPAPCAF-SGNGRQCTANGTECRSGWVGPNGGITNF 347 Query: 347 DNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 DNFAFAMLTVFQCITMEGWTDVLYWVNDA+G +WPW+YFV+LII+GSFFVLNLVLGVLSG Sbjct: 348 DNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSG 407 Query: 407 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSM 466 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENE+EG +E K RN SM Sbjct: 408 EFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGK-RNTSM 466 Query: 467 PTSETESVNTENVAGGDIEGEN---CGA-------------------RLAHRISKSKFSR 504 PTSETESVNTENV+G EGEN CG+ R ISKSK SR Sbjct: 467 PTSETESVNTENVSG---EGENRGCCGSLWCWWRRRGAAKAGPSGCRRWGQAISKSKLSR 523 Query: 505 YWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALL 564 WRRWNRF RR+CRAAVKS FYWLVI LVFLNTLTI+SEHYNQP+WLT++QD ANK LL Sbjct: 524 RWRRWNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLL 583 Query: 565 ALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRL 624 ALFT EML+KMYSLGLQAYFVSLFNRFDCFVVCGGI ETILVE +IMSPLGISV RCVRL Sbjct: 584 ALFTCEMLVKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRL 643 Query: 625 LRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQT 684 LRIFK+TR+W SLSNLVASLLNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDE QT Sbjct: 644 LRIFKVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQT 703 Query: 685 RRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYIL 744 +RSTFDNFPQ+LLTVFQILTGEDWN+VMYDGIMAYGGPS GM+VCIYFIILFICGNYIL Sbjct: 704 KRSTFDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYIL 763 Query: 745 LNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKI 804 LNVFLAIAVDNLADAESL +AQKEE EEKERKK+AR S E K+ KP V + Sbjct: 764 LNVFLAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKN--NKPEVNQIANSD- 820 Query: 805 ELKSITADGESPPATKINMDDLQPNENEDKSPYPN-----PETTGEEDEEEPEMPVGPRP 859 K+ +DD + E+EDK PYP E EE+E+EPE+P GPRP Sbjct: 821 --------------NKVTIDDYR-EEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRP 865 Query: 860 RPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAA 919 R +SEL++KEK P+PE SAFFI S N R+ CH+++N IFTNLIL FI+LSS +LAA Sbjct: 866 RRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHKLINHHIFTNLILVFIMLSSAALAA 925 Query: 920 EDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSV 979 EDP++ SFRN ILG DY FT+IFT+EI+LKMT +GAFLHKG+FCRNYFN+LD+LVV V Sbjct: 926 EDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGV 985 Query: 980 SLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLL 1039 SL+SFGIQSSAI+VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLL Sbjct: 986 SLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLL 1045 Query: 1040 QFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFD 1099 QFMFACIGVQLFKGK Y C+D +K EC+G +I YKDG+VD P+++ R W+NS F+FD Sbjct: 1046 QFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFD 1105 Query: 1100 NVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMN 1159 NVL+AMMALFTVSTFEGWP LLY++IDS+ E+ GPIYN+RVEISIFFIIYIII+AFFMMN Sbjct: 1106 NVLSAMMALFTVSTFEGWPALLYKAIDSNGENIGPIYNHRVEISIFFIIYIIIVAFFMMN 1165 Query: 1160 IFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNST 1219 IFVGFVIVTFQEQGE+EYKNCELDKNQRQCVEYALKARPLRRYIPKN +QYK WYVVNS+ Sbjct: 1166 IFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSS 1225 Query: 1220 YFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYF 1279 FEY+MFVLI+LNT+CLAMQHY QS +F AM+ILNM+FTG+FTVEM+LK+IAFKPKGYF Sbjct: 1226 PFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYF 1285 Query: 1280 SDPWNVFDFLIVIGSIIDVILSETNPAEH----TQCSPSMNAEENSRISITFFRLFRVMR 1335 SD WN FD LIVIGSIIDV LSE +P E + N+EE++RISITFFRLFRVMR Sbjct: 1286 SDAWNTFDSLIVIGSIIDVALSEADPTESENVPVPTATPGNSEESNRISITFFRLFRVMR 1345 Query: 1336 LVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINR 1395 LVKLLSRGEGIRTLLWTFIKSFQALPYVALLI MLFFIYAVIGMQ+FGK+A+ D +INR Sbjct: 1346 LVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKVAMRDNNQINR 1405 Query: 1396 NNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFY 1455 NNNFQTFPQAVLLLFRCATGEAWQ+IMLAC+PGK C PES+ + E CGS+FA+ Y Sbjct: 1406 NNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGE--EYTCGSNFAIVY 1463 Query: 1456 FISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHL 1515 FISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIW+EYDPEAKGRIKHL Sbjct: 1464 FISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPEAKGRIKHL 1523 Query: 1516 DVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTE 1575 DVVTLLRRIQPPLGFGKLCPHRVACKRLV+MNMPLNSDGTVMFNATLFALVRTAL+IKTE Sbjct: 1524 DVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVRTALKIKTE 1583 Query: 1576 GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRK 1635 GNLEQANEELRA+IKKIWK+TSMKLLDQVVPPAGDDEVTVGKFYATFLIQ+YFRKFKKRK Sbjct: 1584 GNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDYFRKFKKRK 1643 Query: 1636 EQGLVGK-PSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDD 1694 EQGLVGK P++ ++LQAGLRTLHDIGPEIRRAIS DL +E E EDD Sbjct: 1644 EQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDE------PEETKREEEDD 1697 Query: 1695 IFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG-SSQGDTESPSHEKLVDST- 1752 +F+R G L GNHV++ SD R + QT TT RPLH+ + DTE P +S Sbjct: 1698 VFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSVC 1757 Query: 1753 FTPSSYSS------TGSNANINNANNTALGRLPRPA----GYPSTVSTVEGHGPPLSPAI 1802 +++S T +NAN+NNAN + RP+ + S H P Sbjct: 1758 HNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGNLEHVSENGHHSSHKHDREPQR 1817 Query: 1803 R--VQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLS 1860 R V+ + + R S + Q +E+ + D E S+E Sbjct: 1818 RSSVKRTRYYETYIRSDSGDEQLPTICREDPEIHGYF-----RDPHCLGEQEYFSSEE-C 1871 Query: 1861 YQDD-----------------------------ENRQLTLPEEDK---RDIRQSPKRGFL 1888 Y+DD + Q L ++D D R+SP+R L Sbjct: 1872 YEDDSSPTWSRQNYGYYSRYPGRNIDSERPRGYHHPQGFLEDDDSPVCYDSRRSPRRRLL 1931 Query: 1889 -RSASLGRRASFHLECLKRQKDR-----GGDISQKTVLPLHLVHHQALAVAGLSPLLQRS 1942 + + RR+SF+ ECL+RQ + +T LPLHL+ Q +AVAGL + Sbjct: 1932 PPTPASHRRSSFNFECLRRQSSQEEVPSSPIFPHRTALPLHLMQQQIMAVAGLDSSKAQK 1991 Query: 1943 HSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGG 2002 +SP+ R +ATPPATP R W P P +++E E+ +++N S PS+H SW P Sbjct: 1992 YSPSHSTRSWATPPATPPYRDWTPCYTPLIQVEQSEALDQVNGSLPSLHRSSWYTDEP-- 2049 Query: 2003 GGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQE 2062 + R P SL VPS SA SLVEAVLISEGLG++A+DPKF+ T E Sbjct: 2050 --DISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHE 2107 Query: 2063 LADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAG-QDRAGGEEDAGCVRARG 2121 +ADACD+TI+EMESAA +L+G NG + P + +D QD G D R Sbjct: 2108 IADACDLTIDEMESAASTLLNGNVRPRANGDVGPLSHRQDYELQDFGPGYSDEEPDPGR- 2166 Query: 2122 RPSEEELQDSRVYVSSL 2138 EE+L D + +++L Sbjct: 2167 --DEEDLADEMICITTL 2181 >gi|110349767 calcium channel, voltage-dependent, L type, alpha 1S subunit [Homo sapiens] Length = 1873 Score = 2298 bits (5954), Expect = 0.0 Identities = 1177/1714 (68%), Positives = 1384/1714 (80%), Gaps = 60/1714 (3%) Query: 77 SSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFA 136 SS Q + + +PKK RPPRAL CLTL+NP+R+ACISIVEWKPFE IILLTIFA Sbjct: 4 SSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLTIFA 63 Query: 137 NCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWN 196 NCVALA+Y+P PEDD+N+ N LE++EY FLI+F++EA +K+IAYG LFH +AYLR+GWN Sbjct: 64 NCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRSGWN 123 Query: 197 LLDFIIVVVGLFSAILEQATKADGANA-LGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQ 255 +LDF IV +G+F+ ILEQ A + KGAG DVKALRAFRVLRPLRLVSGVPSLQ Sbjct: 124 VLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVPSLQ 183 Query: 256 VVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCY--NQEGIADVPAEDDP 313 VVLNSI KAM+PL HIALLVLF++IIYAIIGLELF GKMHKTCY + +A V E+ P Sbjct: 184 VVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENEE-P 242 Query: 314 SPCALETGHGRQCQ-NGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWV 372 SPCA TG GR+C NG+ C+ GW GP HGIT+FDNF F+MLTV+QCITMEGWTDVLYWV Sbjct: 243 SPCA-RTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYWV 301 Query: 373 NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEE 432 NDA+G +WPWIYFVTLI++GSFF+LNLVLGVLSGEF+KEREKAK+RG FQKLREKQQL+E Sbjct: 302 NDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLDE 361 Query: 433 DLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGENCGAR 492 DL+GY+ WITQ E +D E+ EG ++ S+TES+ +I G N Sbjct: 362 DLRGYMSWITQGEVMDVEDFREGK-----LSLDEGGSDTESLY-------EIAGLN---- 405 Query: 493 LAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWL 552 +F R+WR+WNR R KC VKS VFYWLVI +V LNTL+IASEH+NQP WL Sbjct: 406 -----KIIQFIRHWRQWNRIFRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWL 460 Query: 553 TEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMS 612 T +QD AN+ LL+LFT EML+KMY LGL+ YF+S+FNRFDCFVVC GILE +LVE+ M+ Sbjct: 461 TRLQDIANRVLLSLFTTEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMT 520 Query: 613 PLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQL 672 PLGISVLRC+RLLRIFKIT+YW SLSNLVASLLNS+RSIASLLLLLFLFI+IF+LLGMQL Sbjct: 521 PLGISVLRCIRLLRIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQL 580 Query: 673 FGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIY 732 FGG+++F++ + RRS FDNFPQ+L++VFQ+LTGEDW S+MY+GIMAYGGPS+PGMLVCIY Sbjct: 581 FGGRYDFEDTEVRRSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIY 640 Query: 733 FIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVE 792 FIILF+CGNYILLNVFLAIAVDNLA+AESLTSAQK + EEK+R+K+++ P+K +E E Sbjct: 641 FIILFVCGNYILLNVFLAIAVDNLAEAESLTSAQKAKAEEKKRRKMSK-GLPDKSEE--E 697 Query: 793 KPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPE 852 K + + E+K + + I P K+ +D+ + N NE K PYP+ + G+++E+EPE Sbjct: 698 KSTMAKKLEQKPKGEGI------PTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPE 751 Query: 853 MPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILL 912 +P+ PRPRPL+EL LKEKAVP+PEAS+FFIFS N+ R+ CHRIVN T FTN IL FILL Sbjct: 752 IPLSPRPRPLAELQLKEKAVPIPEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILL 811 Query: 913 SSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNIL 972 SS +LAAEDP++ S RN IL + D FTS+FT+EI+LKMT YGAFLHKGSFCRNYFN+L Sbjct: 812 SSAALAAEDPIRADSMRNQILKHFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNML 871 Query: 973 DLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI 1032 DLLVV+VSLIS G++SSAI+VVKILRVLRVLRPLRAINRAKGLKHVVQC+FVAI TIGNI Sbjct: 872 DLLVVAVSLISMGLESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNI 931 Query: 1033 VIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWE 1092 V+VTTLLQFMFACIGVQLFKGK + C+D SK TE EC+G Y YKDG+ ++ R W Sbjct: 932 VLVTTLLQFMFACIGVQLFKGKFFRCTDLSKMTEEECRGYYYVYKDGDPMQIELRHREWV 991 Query: 1093 NSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIII 1152 +S F FDNVL+AMM+LFTVSTFEGWP+LLY++IDS+ ED GPIYN RVE++IFFIIYII+ Sbjct: 992 HSDFHFDNVLSAMMSLFTVSTFEGWPQLLYKAIDSNAEDVGPIYNNRVEMAIFFIIYIIL 1051 Query: 1153 IAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKV 1212 IAFFMMNIFVGFVIVTFQEQGE EYKNCELDKNQRQCV+YALKARPLR YIPKN +QY+V Sbjct: 1052 IAFFMMNIFVGFVIVTFQEQGETEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQV 1111 Query: 1213 WYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIA 1272 WY+V S+YFEYLMF LI+LNTICL MQHY QS +ILN+ FT +FT+EMILKL+A Sbjct: 1112 WYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMA 1171 Query: 1273 FKPKGYFSDPWNVFDFLIVIGSIIDVILSETN----PAEHTQC----SPSMNAEENSRIS 1324 FK +GYF DPWNVFDFLIVIGSIIDVILSE + + C +++ +E++RIS Sbjct: 1172 FKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARIS 1231 Query: 1325 ITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGK 1384 FFRLFRVMRL+KLLSR EG+RTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ+FGK Sbjct: 1232 SAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQMFGK 1291 Query: 1385 IALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGE 1444 IAL D T+INRNNNFQTFPQAVLLLFRCATGEAWQ+I+LAC GK C PES+ + E Sbjct: 1292 IALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPESDYAPGE--E 1349 Query: 1445 TPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEY 1504 CG++FA +YFISFYMLCAFL+INLFVAVIMDNFDYLTRDWSILGPHHLDEFK IWAEY Sbjct: 1350 YTCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWSILGPHHLDEFKAIWAEY 1409 Query: 1505 DPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFA 1564 DPEAKGRIKHLDVVTLLRRIQPPLGFGK CPHRVACKRLV MNMPLNSDGTV FNATLFA Sbjct: 1410 DPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFA 1469 Query: 1565 LVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLI 1624 LVRTAL+IKTEGN EQANEELRAIIKKIWKRTSMKLLDQV+PP GDDEVTVGKFYATFLI Sbjct: 1470 LVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYATFLI 1529 Query: 1625 QEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTL-HDIGPEIRRAISGDLTAEEELDKAM 1683 QE+FRKF KR+E+ G +++ + +QAGLRT+ + PEI R +SGDL AEEEL++AM Sbjct: 1530 QEHFRKFMKRQEE-YYGYRPKKDIVQIQAGLRTIEEEAAPEICRTVSGDLAAEEELERAM 1588 Query: 1684 KEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESP 1743 V AA E+ IFRR GGLFG ++ + ++ P QRPL A + ESP Sbjct: 1589 ---VEAAMEEGIFRRTGGLFGQVDNFLER--TNSLPPVMANQRPLQF--AEIEMEEMESP 1641 Query: 1744 SHEKLVDSTFTPSSYSSTGSNANINNAN-NTALG 1776 + F ++ + AN NNAN N A G Sbjct: 1642 ----VFLEDFPQDPRTNPLARANTNNANANVAYG 1671 Score = 49.7 bits (117), Expect = 3e-05 Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 24/151 (15%) Query: 1965 PPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGA 2024 PP P R+E ++ +S+ S+H E TP +R R + S+ A Sbjct: 1737 PPAPCQCPRVESSMPEDRKSSTPGSLH-----EETPH------SRSTRENT----SRCSA 1781 Query: 2025 PGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSG 2084 P + + L++ L+ GLG A D FI T Q LADAC M EE+E A +L G Sbjct: 1782 P------ATALLIQKALVRGGLGTLAADANFIMATGQALADACQMEPEEVEIMATELLKG 1835 Query: 2085 GAPQSPNGALLPFVNCRDAGQDRAGGEEDAG 2115 ++P G + + C + G ++ G Sbjct: 1836 --REAPEG-MASSLGCLNLGSSLGSLDQHQG 1863 >gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F subunit [Homo sapiens] Length = 1977 Score = 2279 bits (5906), Expect = 0.0 Identities = 1256/2148 (58%), Positives = 1492/2148 (69%), Gaps = 235/2148 (10%) Query: 16 QGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATIST 75 +G +P P+ AN AG PE PG A + + G++G Sbjct: 5 EGGKDTTPEPSPAN-----GAGPGPEWGLCPGPP---------AVEGESSGASG------ 44 Query: 76 VSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIF 135 T ++R Q+ K K +A R PRAL CLTL NP+RR+CISIVEWKPF+I+ILLTIF Sbjct: 45 -LGTPKRRNQHSKHKTVAVASAQRSPRALFCLTLANPLRRSCISIVEWKPFDILILLTIF 103 Query: 136 ANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGW 195 ANCVAL +YIPFPEDDSN N NLE+VEY+FL+IFTVE LK++AYGL+ HP+AY+RNGW Sbjct: 104 ANCVALGVYIPFPEDDSNTANHNLEQVEYVFLVIFTVETVLKIVAYGLVLHPSAYIRNGW 163 Query: 196 NLLDFIIVVVGLFSAILEQATKADG-ANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSL 254 NLLDFIIVVVGLFS +LEQ G A GGK GFDVKALRAFRVLRPLRLVSGVPSL Sbjct: 164 NLLDFIIVVVGLFSVLLEQGPGRPGDAPHTGGKPGGFDVKALRAFRVLRPLRLVSGVPSL 223 Query: 255 QVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPS 314 +VLNSI+KA+VPLLHIALLVLFVIIIYAIIGLELF+G+MHKTCY +D+ AE+DPS Sbjct: 224 HIVLNSIMKALVPLLHIALLVLFVIIIYAIIGLELFLGRMHKTCYFLG--SDMEAEEDPS 281 Query: 315 PCALETGHGRQCQ-NGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 PCA +G GR C N T C+ W GP GITNFDNF FAMLTVFQC+TMEGWTDVLYW+ Sbjct: 282 PCA-SSGSGRACTLNQTECRGRWPGPNGGITNFDNFFFAMLTVFQCVTMEGWTDVLYWMQ 340 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA+G + PW+YFV+L+I GSFFVLNLVLGVLSGEFSKEREKAKARGDFQK REKQQ+EED Sbjct: 341 DAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKQREKQQMEED 400 Query: 434 LKGYLDWITQAEDIDPEN----------EDEGMDEEKPR--------------------- 462 L+GYLDWITQAE++D E+ +EG +P+ Sbjct: 401 LRGYLDWITQAEELDMEDPSADDNLGSMAEEGRAGHRPQLAELTNRRRGRLRWFSHSTRS 460 Query: 463 ------NMSMPTSETESVNTENVAGGDIEG--ENCGARLAHRISKSKFSRYWRRWNRFCR 514 + S+P S+T S+ + EG +C R ++I K++ R RR NR R Sbjct: 461 THSTSSHASLPASDTGSMTETQGDEDEEEGALASC-TRCLNKIMKTRVCRRLRRANRVLR 519 Query: 515 RKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLK 574 +CR AVKSN YW V+ LVFLNTLTIASEH+ QP WLT++Q+ ANK LL LFT EMLLK Sbjct: 520 ARCRRAVKSNACYWAVLLLVFLNTLTIASEHHGQPVWLTQIQEYANKVLLCLFTVEMLLK 579 Query: 575 MYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYW 634 +Y LG AY S FNRFDCFVVCGGILET LVE M PLGISVLRCVRLLRIFK+TR+W Sbjct: 580 LYGLGPSAYVSSFFNRFDCFVVCGGILETTLVEVGAMQPLGISVLRCVRLLRIFKVTRHW 639 Query: 635 NSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQ 694 SLSNLVASLLNS++SIASLLLLLFLFIIIFSLLGMQLFGGKFNFD+ T+RSTFD FPQ Sbjct: 640 ASLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDQTHTKRSTFDTFPQ 699 Query: 695 SLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVD 754 +LLTVFQILTGEDWN VMYDGIMAYGGP FPGMLVCIYFIILFICGNYILLNVFLAIAVD Sbjct: 700 ALLTVFQILTGEDWNVVMYDGIMAYGGPFFPGMLVCIYFIILFICGNYILLNVFLAIAVD 759 Query: 755 NLADAESLTSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGE 814 NLA ++ T+ K E+ E+ P++ + LV P V + +EE + Sbjct: 760 NLASGDAGTAKDKGGEKSNEKD------LPQENEGLV--PGVEKEEEEGARREGA----- 806 Query: 815 SPPATKINMDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPM 874 D++ E E+ EE+EEE E L E+ KEK VP+ Sbjct: 807 ----------DMEEEEEEE-----------EEEEEEEEEEGAGGVELLQEVVPKEKVVPI 845 Query: 875 PEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILG 934 PE SAFF S N R CH +++ +FTNLIL FI+LSS+SLAAEDP++ SFRNHILG Sbjct: 846 PEGSAFFCLSQTNPLRKGCHTLIHHHVFTNLILVFIILSSVSLAAEDPIRAHSFRNHILG 905 Query: 935 NADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVV 994 DY FTSIFT+EI+LKMT +GAFLH+GSFCR++FN+LDLLVVSVSLISFGI SSAI+VV Sbjct: 906 YFDYAFTSIFTVEILLKMTVFGAFLHRGSFCRSWFNMLDLLVVSVSLISFGIHSSAISVV 965 Query: 995 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGK 1054 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNI+IVTTLLQFMFACIGVQLFKGK Sbjct: 966 KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGK 1025 Query: 1055 LYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTF 1114 YTC+D +K T ECKG+++ Y DG+V P+++ R W NS F+FDNVL+AMMALFTVSTF Sbjct: 1026 FYTCTDEAKHTPQECKGSFLVYPDGDVSRPLVRERLWVNSDFNFDNVLSAMMALFTVSTF 1085 Query: 1115 EGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE 1174 EGWP LLY++ID++ ED GPIYNYRVEIS+FFI+YIIIIAFFMMNIFVGFVI+TF+ QGE Sbjct: 1086 EGWPALLYKAIDAYAEDHGPIYNYRVEISVFFIVYIIIIAFFMMNIFVGFVIITFRAQGE 1145 Query: 1175 QEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTI 1234 QEY+NCELDKNQRQCVEYALKA+PLRRYIPKN HQY+VW VNS FEYLMF+LILLNT+ Sbjct: 1146 QEYQNCELDKNQRQCVEYALKAQPLRRYIPKNPHQYRVWATVNSAAFEYLMFLLILLNTV 1205 Query: 1235 CLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGS 1294 LAMQHY Q+ F AM+ILNM+FTGLFT+EM+LK+IAFKPK YF+D WN FD LIV+GS Sbjct: 1206 ALAMQHYEQTAPFNYAMDILNMVFTGLFTIEMVLKIIAFKPKHYFTDAWNTFDALIVVGS 1265 Query: 1295 IIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFI 1354 I+D+ ++E N H ++E++SRISITFFRLFRVMRLVKLLS+GEGIRTLLWTFI Sbjct: 1266 IVDIAVTEVNNGGHL----GESSEDSSRISITFFRLFRVMRLVKLLSKGEGIRTLLWTFI 1321 Query: 1355 KSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCAT 1414 KSFQALPYVALLI M+FFIYAVIGMQ+FGK+AL D T+INRNNNFQTFPQAVLLLFRCAT Sbjct: 1322 KSFQALPYVALLIAMIFFIYAVIGMQMFGKVALQDGTQINRNNNFQTFPQAVLLLFRCAT 1381 Query: 1415 GEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAV 1474 GEAWQ+IMLA +PG +C PES+ E CGS+FA+ YFISF+MLCAFLIINLFVAV Sbjct: 1382 GEAWQEIMLASLPGNRCDPESDFGPGE--EFTCGSNFAIAYFISFFMLCAFLIINLFVAV 1439 Query: 1475 IMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLC 1534 IMDNFDYLTRDWSILGPHHLDEFKRIW+EYDP AKGRIKHLDVV LLRRIQPPLGFGKLC Sbjct: 1440 IMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLC 1499 Query: 1535 PHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWK 1594 PHRVACKRLV+MNMPLNSDGTV FNATLFALVRT+L+IKTEGNLEQAN+ELR +IKKIWK Sbjct: 1500 PHRVACKRLVAMNMPLNSDGTVTFNATLFALVRTSLKIKTEGNLEQANQELRIVIKKIWK 1559 Query: 1595 RTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALS-LQA 1653 R KLLD+V+PP ++EVTVGKFYATFLIQ+YFRKF++RKE+GL+G + + S LQA Sbjct: 1560 RMKQKLLDEVIPPPDEEEVTVGKFYATFLIQDYFRKFRRRKEKGLLGNDAAPSTSSALQA 1619 Query: 1654 GLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSD 1713 GLR+L D+GPE+R+A++ D EEE +E V E D+ Sbjct: 1620 GLRSLQDLGPEMRQALTCDTEEEEE---EGQEGVEEEDEKDL------------------ 1658 Query: 1714 GRSAFPQTFTTQRPLHINKAGSSQGDTES---PSHEKLVDS-TFTPSS---YSSTGSNAN 1766 T + +++ + +G S P ++L DS +F PS + T S + Sbjct: 1659 ---------ETNKATMVSQPSARRGSGISVSLPVGDRLPDSLSFGPSDDDRGTPTSSQPS 1709 Query: 1767 INNANNTALGRLPRPAGYPSTVSTV--EGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAA 1824 + A + R G + + T+ EG+ P Sbjct: 1710 VPQAGSNTHRR-----GSGALIFTIPEEGNSQP-------------------------KG 1739 Query: 1825 MAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKR--DIRQS 1882 GQ + +DE ++++ E P L P +R D Sbjct: 1740 TKGQNKQDEDEEVPDRLSYLDEQAGTPPC-------------SVLLPPHRAQRYMDGHLV 1786 Query: 1883 PKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRS 1942 P+R L GR+ SF ++CL+RQ G LP+ +H+ R+ Sbjct: 1787 PRRRLLPPTPAGRKPSFTIQCLQRQ----GSCED---LPIPGTYHRG-----------RN 1828 Query: 1943 HSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGG 2002 P +ATPP RG L EG L Sbjct: 1829 SGPNRAQGSWATPP----QRGRLLYAPLLLVEEGAAGEGYL------------------- 1865 Query: 2003 GGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQE 2062 G SS R L VP P GSA SLVEAVLISEGLG FA+DP+F+ + QE Sbjct: 1866 GRSSGPLRTF-TCLHVPGTHSDPSHGKRGSADSLVEAVLISEGLGLFARDPRFVALAKQE 1924 Query: 2063 LADACDMTIEEMESAADNILSGGAPQ--SPNGALLPFVNCRDAGQDRA 2108 +ADAC +T++EM++AA ++L+ G S ++L + D G + A Sbjct: 1925 IADACRLTLDEMDNAASDLLAQGTSSLYSDEESILSRFDEEDLGDEMA 1972 >gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo sapiens] Length = 2261 Score = 776 bits (2003), Expect = 0.0 Identities = 405/869 (46%), Positives = 565/869 (65%), Gaps = 56/869 (6%) Query: 790 LVEKPAVGESKEEKIELKSITADGESPPATK--INMDDLQPNENEDKSPYPNPETTGEED 847 +V P+ ++ K K + PPA +N +Q N+N + P P E +E+ Sbjct: 1146 IVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKEEEKKEE 1205 Query: 848 EEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLIL 907 EE+ GP+P MP S+ FI S+ N R CH I+N F IL Sbjct: 1206 EEDDRGEDGPKP--------------MPPYSSMFILSTTNPLRRLCHYILNLRYFEMCIL 1251 Query: 908 FFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRN 967 I +SSI+LAAEDPVQ + RN++L DYVFT +FT E+++KM G LH+G++ R+ Sbjct: 1252 MVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRD 1311 Query: 968 YFNILDLLVVSVSLISFGIQSSA----INVVKILRVLRVLRPLRAINRAKGLKHVVQCVF 1023 +NILD +VVS +L++F ++ IN +K LRVLRVLRPL+ I R LK V CV Sbjct: 1312 LWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVV 1371 Query: 1024 VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH 1083 +++ + NI+IV L F+FA + VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV Sbjct: 1372 NSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVK- 1430 Query: 1084 PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS 1143 + R W+ +F +DNVL A++ LFTVST EGWP++L S+D+ E++GP YR+E+S Sbjct: 1431 --ARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMS 1488 Query: 1144 IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI 1203 IF+++Y ++ FF +NIFV +I+TFQEQG++ + L+KN+R C+++A+ A+PL R++ Sbjct: 1489 IFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHM 1548 Query: 1204 PKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGL 1261 P+N+ QY++W V S FEY + +I LNTI L M+ YG S ++ A+ + N++FT L Sbjct: 1549 PQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSL 1608 Query: 1262 FTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENS 1321 F++E +LK++AF YF D WN+FDF+ V+GSI D++++E N+ Sbjct: 1609 FSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITDILVTEFG---------------NN 1653 Query: 1322 RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQV 1381 I+++F RLFR RL+KLL +G IR LLWTF++SF+ALPYV LLI MLFFIYA+IGMQV Sbjct: 1654 FINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQV 1713 Query: 1382 FGKIALN--------DTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAP 1433 FG I ++ D +I +NNF+TF QA++LLFR ATGEAW +IML+C+ GK C Sbjct: 1714 FGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKPC-- 1771 Query: 1434 ESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH 1493 NS CG+ FA FYF+SF LC+FL++NLFVAVIMDNF+YLTRD SILGPHH Sbjct: 1772 ---DKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHH 1828 Query: 1494 LDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSD 1553 LDE+ R+WAEYDP A GRI + D+ +LLR I PPLG GK CPHRVACKRL+ M++P+ D Sbjct: 1829 LDEYVRVWAEYDPAACGRIHYKDMYSLLRVISPPLGLGKKCPHRVACKRLLRMDLPVADD 1888 Query: 1554 GTVMFNATLFALVRTALRIKTE---GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD 1610 TV FN+TL AL+RTAL IK + +Q + ELR + IW S K LD +V P Sbjct: 1889 NTVHFNSTLMALIRTALDIKIAKGGADKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKS 1948 Query: 1611 DEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 ++TVGK YA +I EY+R+ K +K Q + Sbjct: 1949 TDLTVGKIYAAMMIMEYYRQSKAKKLQAM 1977 Score = 671 bits (1730), Expect = 0.0 Identities = 383/827 (46%), Positives = 507/827 (61%), Gaps = 64/827 (7%) Query: 18 SNYGSPRPA-HANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTV 76 + +G PA + + AAAG+ GA S Q G G + Sbjct: 2 ARFGDEMPARYGGGGSGAAAGVVVGSGGGRGAGGSRQG-----------GQPGAQRMYKQ 50 Query: 77 SSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLT 133 S QR R Y P +Q T R +L + N +R+ I EW PFE +IL T Sbjct: 51 SMAQRARTMALYNPIPVRQNCLTVNR---SLFLFSEDNVVRKYAKKITEWPPFEYMILAT 107 Query: 134 IFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN 193 I ANC+ LA+ P+DD + L+ E F+ IF EA +K+IA G FH +YLRN Sbjct: 108 IIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRN 167 Query: 194 GWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPS 253 GWN++DF++V+ G+ + + G FD++ LRA RVLRPL+LVSG+PS Sbjct: 168 GWNVMDFVVVLTGILATV----------------GTEFDLRTLRAVRVLRPLKLVSGIPS 211 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 LQVVL SI+KAM+PLL I LL+ F I+I+AIIGLE +MGK H TC+ +EG D+ E P Sbjct: 212 LQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCF-EEGTDDIQGES-P 269 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 +PC E R C NGT C+P W+GP +GIT FDN FA+LTVFQCITMEGWTD+LY N Sbjct: 270 APCGTEEP-ARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSN 328 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA G W W+YF+ LIIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E + Sbjct: 329 DASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERE 388 Query: 434 LKGYLDWITQAEDIDPENEDEGMDEEKP-----RNMSMPTSETESVNTENVAGGDIEGEN 488 L GY++WI++AE++ ++ ++ P R ++ S+T+ +N E + + Sbjct: 389 LNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIKKSKTDLLNPEEAEDQLADIAS 448 Query: 489 CG---ARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEH 545 G AR + + +K + S ++ + R R R VK+ FYW V+ LV LNTL +A H Sbjct: 449 VGSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVH 508 Query: 546 YNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETIL 605 YNQP WL++ A L LF +EM +KMY LG + YF S FN FDC V+ G I E I Sbjct: 509 YNQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIW 568 Query: 606 VETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIF 665 K + GISVLR +RLLRIFK+T+YW SL NLV SLLNS++SI SLL LLFLFI++F Sbjct: 569 AVIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVF 628 Query: 666 SLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP 725 +LLGMQLFGG+FNFDE T + FD FP +++TVFQILTGEDWN VMYDGI + GG Sbjct: 629 ALLGMQLFGGQFNFDE-GTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQ-G 686 Query: 726 GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERK--------- 776 GM+ IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EEEE +K Sbjct: 687 GMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEV 746 Query: 777 ------KLARTASPEKKQELVEKPA--VGESKEEKIELKSITADGES 815 A + K+Q+ +KPA V E + ++ +++ A E+ Sbjct: 747 AEVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREA 793 Score = 202 bits (513), Expect = 4e-51 Identities = 176/705 (24%), Positives = 317/705 (44%), Gaps = 120/705 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 + K+++ + + P ++ L+ NP+RR C I+ + FE+ IL+ I + + Sbjct: 1200 EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI 1259 Query: 140 ALAIYIPFPEDDSNATNSNLERV-EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198 ALA P NA +N+ R +Y+F +FT E +K+I GL+ H AY R+ WN+L Sbjct: 1260 ALAAEDPV---QPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNIL 1316 Query: 199 DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258 DFI+V L + +K N +K+LR RVLRPL+ + +P L+ V Sbjct: 1317 DFIVVSGALVAFAFTGNSKGKDINT---------IKSLRVLRVLRPLKTIKRLPKLKAVF 1367 Query: 259 NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK-MHKTCYNQEGIADVPAEDDPSPCA 317 + ++ ++ + +I ++ + + I+A++ ++LF GK H T ++E D Sbjct: 1368 DCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDC---------- 1417 Query: 318 LETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV- 376 G + V + K+ ++DN +A+LT+F T EGW VL DA Sbjct: 1418 --RGKYLLYEKNEVKARDREWKKYEF-HYDNVLWALLTLFTVSTGEGWPQVLKHSVDATF 1474 Query: 377 --------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQ 428 R I++V ++ FF +N+ + ++ F ++ GD K+ E+ Sbjct: 1475 ENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KMMEEY 1525 Query: 429 QLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGEN 488 LE++ + +D+ A KP MP Sbjct: 1526 SLEKNERACIDFAISA---------------KPLTRHMP--------------------- 1549 Query: 489 CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ 548 ++K S +R W V S F + ++ ++ LNT+ + + Y Sbjct: 1550 ----------QNKQSFQYRMWQ---------FVVSPPFEYTIMAMIALNTIVLMMKFYGA 1590 Query: 549 PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVET 608 N +LF+ E +LK+ + G+ YF +N FD V G I + ILV Sbjct: 1591 SVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITD-ILVTE 1649 Query: 609 KIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLL 668 + + +S LR R R+ K+ R ++ L+ + + S +++ + LL+ + I++++ Sbjct: 1650 FGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1709 Query: 669 GMQLFGG--------KFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAY 719 GMQ+FG + DE Q T + F F Q+L+ +F+ TGE W+++M + Sbjct: 1710 GMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGK 1769 Query: 720 GGPSFPGML--------VCIYFI-ILFICGNYILLNVFLAIAVDN 755 G+L YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1770 PCDKNSGILTRECGNEFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1813 Score = 143 bits (360), Expect = 2e-33 Identities = 179/785 (22%), Positives = 325/785 (41%), Gaps = 161/785 (20%) Query: 480 AGGDIEGENCGARLAHRISKSKFSRYWRRWNRF-CRRKCRAAVKS-------NV------ 525 AGG +G GA+ ++ S ++ +R +N R+ C +S NV Sbjct: 33 AGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAK 92 Query: 526 -------FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKM 575 F ++++ + N + +A E + + ++E D + +F E +K+ Sbjct: 93 KITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKI 152 Query: 576 YSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT 631 +LG +Y + +N D VV GIL T+ E + LR VR+LR K+ Sbjct: 153 IALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTE------FDLRTLRAVRVLRPLKLV 206 Query: 632 RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF-------DEMQT 684 SL ++ S++ ++ + + LLLF I+IF+++G++ + GKF+ D++Q Sbjct: 207 SGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQG 266 Query: 685 RR------------------------------STFDNFPQSLLTVFQILTGEDWNSVMYD 714 + FDN ++LTVFQ +T E W ++Y+ Sbjct: 267 ESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYN 326 Query: 715 GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE 774 A G +YFI L I G++ +LN+ L + A +E+E Sbjct: 327 SNDASGNT-----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERE 368 Query: 775 RKKLARTASPEKKQELVEKPAVGE----SKEEKIELKSITADGES--PPATKINMDDLQP 828 R + R ++Q+ +E+ G SK E++ L DGE P + ++ Sbjct: 369 RVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDGALRRTTIK- 427 Query: 829 NENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNR 888 + K+ NPE ED+ VG P + +K + E S FF R Sbjct: 428 ---KSKTDLLNPEEA--EDQLADIASVGS---PFARASIKSAKL---ENSTFF-HKKERR 475 Query: 889 FRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEI 948 R R+V F +L + L+++ +A Q + + L A+++F +F E+ Sbjct: 476 MRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQ-PEWLSDFLYYAEFIFLGLFMSEM 534 Query: 949 ILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRP 1005 +KM G + + FN D V+ S+ I+ + +LR LR+LR Sbjct: 535 FIKMYGLGT----RPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRI 590 Query: 1006 LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT 1065 + L+++V + ++++I +++ + L +FA +G+QLF G+ + + + T Sbjct: 591 FKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQ-FNFDEGTPPT 649 Query: 1066 EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI 1125 +FD AA+M +F + T E W E++Y I Sbjct: 650 -------------------------------NFDTFPAAIMTVFQILTGEDWNEVMYDGI 678 Query: 1126 DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEY 1177 S +G + SI+FI+ + + ++N+F+ + +T EQ E+E Sbjct: 679 KSQGGVQGGMV-----FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEA 733 Query: 1178 KNCEL 1182 N +L Sbjct: 734 ANQKL 738 Score = 116 bits (291), Expect = 2e-25 Identities = 96/331 (29%), Positives = 163/331 (49%), Gaps = 33/331 (9%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILGNA 936 + F+FS +N R +I F +IL I+ + I LA E P + + L + Sbjct: 77 SLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDT 136 Query: 937 DYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI-SFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV ++ + G + ++ Sbjct: 137 EPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFD----LR 192 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ +FA IG++ + GK Sbjct: 193 TLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252 Query: 1056 YT------CSDSSKQTEAEC--KGNYITYKDGEVDHPIIQPRSWE---NSKFDFDNVLAA 1104 +T D ++ A C + T +G P WE N FDN+L A Sbjct: 253 HTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPY-----WEGPNNGITQFDNILFA 307 Query: 1105 MMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 1164 ++ +F T EGW +LLY S D+ G +N+ ++FI III +FFM+N+ +G Sbjct: 308 VLTVFQCITMEGWTDLLYNSNDA----SGNTWNW-----LYFIPLIIIGSFFMLNLVLGV 358 Query: 1165 VIVTFQEQGEQ-EYKNCELDKNQRQCVEYAL 1194 + F ++ E+ E + L ++Q +E L Sbjct: 359 LSGEFAKERERVENRRAFLKLRRQQQIEREL 389 Score = 114 bits (286), Expect = 8e-25 Identities = 77/294 (26%), Positives = 138/294 (46%), Gaps = 42/294 (14%) Query: 1195 KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL 1254 K R +R YI + +V + F + + L+ LNT+C+A+ HY Q + Sbjct: 472 KERRMRFYIRR---------MVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYA 522 Query: 1255 NMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPS 1314 +F GLF EM +K+ + YF +N FD ++IGSI +VI + P Sbjct: 523 EFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKP--------- 573 Query: 1315 MNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIY 1374 + I+ R R++R+ K+ +R L+ + + S +++ + L+ + ++ Sbjct: 574 -----GTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVF 628 Query: 1375 AVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPE 1434 A++GMQ+FG + E NF TFP A++ +F+ TGE W ++M Sbjct: 629 ALLGMQLFG--GQFNFDEGTPPTNFDTFPAAIMTVFQILTGEDWNEVMY----------- 675 Query: 1435 SEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1485 ++G G F++ YFI + + ++N+F+A+ +DN LT+D Sbjct: 676 --DGIKSQGGVQGGMVFSI-YFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 726 Score = 94.4 bits (233), Expect = 1e-18 Identities = 79/311 (25%), Positives = 143/311 (45%), Gaps = 41/311 (13%) Query: 514 RRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNW-LTEVQDTANKALLALFTAEML 572 RR C + F ++ ++ ++++ +A+E QPN V + +FT EM+ Sbjct: 1234 RRLCHYILNLRYFEMCILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMV 1293 Query: 573 LKMYSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLG-ISVLRCVRLLRI 627 +KM LGL AYF L+N D VV G ++ + I LR +R+LR Sbjct: 1294 IKMIDLGLVLHQGAYFRDLWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRP 1353 Query: 628 FKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF---------- 677 K + L + ++NS++++ ++L++ LF+ IF+++ +QLF GKF Sbjct: 1354 LKTIKRLPKLKAVFDCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEF 1413 Query: 678 -----------NFDEMQTRRST-------FDNFPQSLLTVFQILTGEDWNSVM---YDGI 716 +E++ R +DN +LLT+F + TGE W V+ D Sbjct: 1414 EKDCRGKYLLYEKNEVKARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDAT 1473 Query: 717 MAYGGPSFPG--MLVCIYFIILFICGNYILLNVFLAIAVDNLAD-AESLTSAQKEEEEEK 773 GPS PG M + I++++ F+ + +N+F+A+ + + + + E+ E+ Sbjct: 1474 FENQGPS-PGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNER 1532 Query: 774 ERKKLARTASP 784 A +A P Sbjct: 1533 ACIDFAISAKP 1543 Score = 82.0 bits (201), Expect = 6e-15 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 62/297 (20%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N + L + S A + L +F +F++E LKV+A+G+L Sbjct: 1567 PFEYTIMAMIALNTIVLMMKF---YGASVAYENALRVFNIVFTSLFSLECVLKVMAFGIL 1623 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + G N + ++ LR FR R Sbjct: 1624 ----NYFRDAWNIFDFVTVLGSITDILVTEF----GNNFI-------NLSFLRLFRAARL 1668 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F GI Sbjct: 1669 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF---------GNIGI 1719 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 DV ED T H NF F A++ +F+ T E Sbjct: 1720 -DVEDEDSDEDEFQITEH---------------------NNFRTFFQALMLLFRSATGEA 1757 Query: 365 WTDVLY-------------WVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ + G ++ + YFV+ I + SF +LNL + V+ F Sbjct: 1758 WHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1814 Score = 67.8 bits (164), Expect = 1e-10 Identities = 70/302 (23%), Positives = 120/302 (39%), Gaps = 81/302 (26%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + ++ F G+F E +K+IA F Sbjct: 100 FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159 Query: 1274 KPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRV 1333 Y + WNV DF++V+ I+ + +E + R RV Sbjct: 160 HKGSYLRNGWNVMDFVVVLTGILATVGTE--------------------FDLRTLRAVRV 199 Query: 1334 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF-GKI------- 1385 +R +KL+S ++ +L + +K+ L + LL+ I+A+IG++ + GK Sbjct: 200 LRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEE 259 Query: 1386 ----------ALNDTTEINR---------------NNNFQTFPQ---AVLLLFRCATGEA 1417 A T E R NN F AVL +F+C T E Sbjct: 260 GTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEG 319 Query: 1418 WQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMD 1477 W D++ NS + G+++ YFI ++ +F ++NL + V+ Sbjct: 320 WTDLLY---------------NSNDAS---GNTWNWLYFIPLIIIGSFFMLNLVLGVLSG 361 Query: 1478 NF 1479 F Sbjct: 362 EF 363 >gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B subunit [Homo sapiens] Length = 2339 Score = 769 bits (1986), Expect = 0.0 Identities = 429/947 (45%), Positives = 590/947 (62%), Gaps = 74/947 (7%) Query: 764 SAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESP----PAT 819 + +KE E++ +K A +K++EL + +E +L++ P P+T Sbjct: 991 AVEKETTEKEATEKEAEIVEADKEKELRNH----QPREPHCDLETSGTVTVGPMHTLPST 1046 Query: 820 KINMDDLQPNENEDK-------SPYPNPETTGEEDEEEPEMPVGPRPR----PLSELHLK 868 + + QP + +++ S P+P T P M GP P + L+ Sbjct: 1047 CLQKVEEQPEDADNQRNVTRMGSQPPDPNTI----VHIPVMLTGPLGEATVVPSGNVDLE 1102 Query: 869 EKAV----------------PMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILL 912 +A P+ S+ F S N R CH IV F +IL I L Sbjct: 1103 SQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFCHYIVTMRYFEVVILVVIAL 1162 Query: 913 SSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNIL 972 SSI+LAAEDPV+ S RN+ L DY+FT +FT E+++KM G LH G++ R+ +NIL Sbjct: 1163 SSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNIL 1222 Query: 973 DLLVVSVSLISFGIQSSA---INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTI 1029 D +VVS +L++F S IN +K LRVLRVLRPL+ I R LK V CV +++ + Sbjct: 1223 DFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNV 1282 Query: 1030 GNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPR 1089 NI+IV L F+FA I VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV+ QPR Sbjct: 1283 LNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELERDCRGQYLDYEKEEVE---AQPR 1339 Query: 1090 SWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIY 1149 W+ F +DNVL A++ LFTVST EGWP +L S+D+ E++GP YR+E+SIF+++Y Sbjct: 1340 QWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVY 1399 Query: 1150 IIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQH- 1208 ++ FF +NIFV +I+TFQEQG++ C L+KN+R C+++A+ A+PL RY+P+N+ Sbjct: 1400 FVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFAISAKPLTRYMPQNRQS 1459 Query: 1209 -QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMI 1267 QYK W V S FEY + +I LNT+ L M+ Y +++ + LN++FT +F++E + Sbjct: 1460 FQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECV 1519 Query: 1268 LKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITF 1327 LK+IAF YF D WNVFDF+ V+GSI D++++E AE N+ I+++F Sbjct: 1520 LKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEI-------------AETNNFINLSF 1566 Query: 1328 FRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIAL 1387 RLFR RL+KLL +G IR LLWTF++SF+ALPYV LLI MLFFIYA+IGMQVFG IAL Sbjct: 1567 LRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIAL 1626 Query: 1388 NDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPC 1447 +D T INR+NNF+TF QA++LLFR ATGEAW +IML+C+ + C E +N+TE C Sbjct: 1627 DDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQAC---DEQANATE----C 1679 Query: 1448 GSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPE 1507 GS FA FYF+SF LC+FL++NLFVAVIMDNF+YLTRD SILGPHHLDEF R+WAEYDP Sbjct: 1680 GSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPA 1739 Query: 1508 AKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL-NSDGTVMFNATLFALV 1566 A GRI + D+ +L+ + PPLG GK CP RVA KRLV MNMP+ N D TV F +TL AL+ Sbjct: 1740 ACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALI 1799 Query: 1567 RTALRIK---TEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFL 1623 RTAL IK Q + ELR I +W K LD +VPP DE+TVGK YA + Sbjct: 1800 RTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALM 1859 Query: 1624 IQEYFRKFKKRKE--QGLVGKPSQRNALSLQAGLR-TLHDIGPEIRR 1667 I +++++ K ++ Q G SQ +SL L+ TL P + R Sbjct: 1860 IFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLR 1906 Score = 648 bits (1671), Expect = 0.0 Identities = 371/803 (46%), Positives = 486/803 (60%), Gaps = 59/803 (7%) Query: 89 PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFP 148 P KQ T R +L + N +R+ I EW PFE +IL TI ANC+ LA+ P Sbjct: 63 PVKQNCFTVNR---SLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLP 119 Query: 149 EDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLF 208 + D + L+ E F+ IF EA +K+IA G +FH +YLRNGWN++DF++V+ G+ Sbjct: 120 DGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGI- 178 Query: 209 SAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPL 268 L G FD++ LRA RVLRPL+LVSG+PSLQVVL SI+KAMVPL Sbjct: 179 ---------------LATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPL 223 Query: 269 LHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQN 328 L I LL+ F I+++AIIGLE +MGK HK C+ A+ P D PC E R C+ Sbjct: 224 LQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAE-PVGD--FPCGKEAP-ARLCEG 279 Query: 329 GTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTL 388 T C+ W GP GITNFDN FA+LTVFQCITMEGWTD+LY NDA G W W+YF+ L Sbjct: 280 DTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPL 339 Query: 389 IIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDID 448 IIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E +L GYL+WI +AE++ Sbjct: 340 IIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVM 399 Query: 449 PENEDEGMDEEKP----RNMSMPTSETESVNTENVAGGDIEGENCG-----ARLAHRISK 499 ED +E+ P + + S + ++ E G D + C AR + + K Sbjct: 400 LAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAEE--GEDRFADLCAVGSPFARASLKSGK 457 Query: 500 SKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTA 559 ++ S Y+RR + R R VK+ FYW+V+ +V LNTL +A HYNQP LT A Sbjct: 458 TESSSYFRRKEKMFRFFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFA 517 Query: 560 NKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVL 619 L LF EM LKMY LG ++YF S FN FD V+ G + E + K S GISVL Sbjct: 518 EFVFLGLFLTEMSLKMYGLGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVL 577 Query: 620 RCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF 679 R +RLLRIFK+T+YW+SL NLV SLLNS++SI SLL LLFLFI++F+LLGMQLFGG+FNF Sbjct: 578 RALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNF 637 Query: 680 DEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFIC 739 + +T + FD FP ++LTVFQILTGEDWN+VMY GI + GG S GM YFI+L + Sbjct: 638 QD-ETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIESQGGVS-KGMFSSFYFIVLTLF 695 Query: 740 GNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE-------------- 785 GNY LLNVFLAIAVDNLA+A+ LT +EE EE +KLA + E Sbjct: 696 GNYTLLNVFLAIAVDNLANAQELTK-DEEEMEEAANQKLALQKAKEVAEVSPMSAANISI 754 Query: 786 --KKQELVEKPAVGESKEEKIELKSITAD-----GESPPATKINMDDLQPNENEDKSPYP 838 ++Q + +V E + ++ L+++ A E P ++ + + K+ Sbjct: 755 AARQQNSAKARSVWEQRASQLRLQNLRASCEALYSEMDPEERLRFATTRHLRPDMKTHLD 814 Query: 839 NPETTGEEDEEEPEMPVGPRPRP 861 P E + PVG + RP Sbjct: 815 RPLVV-ELGRDGARGPVGGKARP 836 Score = 216 bits (550), Expect = 2e-55 Identities = 179/716 (25%), Positives = 322/716 (44%), Gaps = 113/716 (15%) Query: 64 LMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPR------ALLCLTLKNPIRRAC 117 L G G AT+ + + Q GK + + PR ++ CL+ N +RR C Sbjct: 1084 LTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFC 1143 Query: 118 ISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK 177 IV + FE++IL+ I + +ALA P D N+ L+ ++Y+F +FT E +K Sbjct: 1144 HYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPR--NNALKYLDYIFTGVFTFEMVIK 1201 Query: 178 VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR 237 +I GLL HP AY R+ WN+LDF IVV G A +K N +K+LR Sbjct: 1202 MIDLGLLLHPGAYFRDLWNILDF-IVVSGALVAFAFSGSKGKDINT---------IKSLR 1251 Query: 238 AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT 297 RVLRPL+ + +P L+ V + ++ ++ +L+I ++ + + I+A+I ++LF GK Sbjct: 1252 VLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFF-Y 1310 Query: 298 CYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVF 357 C ++ + E + Q W K ++DN +A+LT+F Sbjct: 1311 CTDESKELERDCRGQYLDYEKEEVEAQPRQ--------W---KKYDFHYDNVLWALLTLF 1359 Query: 358 QCITMEGWTDVLYWVNDAVGRDWP---------WIYFVTLIIIGSFFVLNLVLGVLSGEF 408 T EGW VL DA + I++V ++ FF +N+ + ++ F Sbjct: 1360 TVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITF 1419 Query: 409 SKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPT 468 ++ GD K+ + LE++ + +D+ A KP MP Sbjct: 1420 QEQ-------GD--KVMSECSLEKNERACIDFAISA---------------KPLTRYMP- 1454 Query: 469 SETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYW 528 +++ S ++ W V S F + Sbjct: 1455 ------------------------------QNRQSFQYKTW---------TFVVSPPFEY 1475 Query: 529 LVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLF 588 ++ ++ LNT+ + + Y+ P + N ++F+ E +LK+ + G+ YF + Sbjct: 1476 FIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAW 1535 Query: 589 NRFDCFVVCGGILETILVE-TKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNS 647 N FD V G I + ++ E + + + +S LR R R+ K+ R ++ L+ + + S Sbjct: 1536 NVFDFVTVLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQS 1595 Query: 648 VRSIASLLLLLFLFIIIFSLLGMQLFGG-KFNFDEMQTRRSTFDNFPQSLLTVFQILTGE 706 +++ + LL+ + I++++GMQ+FG + D R + F F Q+L+ +F+ TGE Sbjct: 1596 FKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGE 1655 Query: 707 DWNSVMYDGIMAYGGPSFPGMLVC------IYFI-ILFICGNYILLNVFLAIAVDN 755 W+ +M + C YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1656 AWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1710 Score = 127 bits (320), Expect = 9e-29 Identities = 77/275 (28%), Positives = 135/275 (49%), Gaps = 35/275 (12%) Query: 1215 VVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFK 1274 +V + F +++ ++ LNT+C+AM HY Q + +F GLF EM LK+ Sbjct: 478 MVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLG 537 Query: 1275 PKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRVM 1334 P+ YF +N FDF +++GS+ +V+ + P S I+ R R++ Sbjct: 538 PRSYFRSSFNCFDFGVIVGSVFEVVWAAIKP--------------GSSFGISVLRALRLL 583 Query: 1335 RLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF-GKIALNDTTEI 1393 R+ K+ +R L+ + + S +++ + L+ + ++A++GMQ+F G+ D T Sbjct: 584 RIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETP- 642 Query: 1394 NRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAV 1453 NF TFP A+L +F+ TGE W +M + ES+ S F+ Sbjct: 643 --TTNFDTFPAAILTVFQILTGEDWNAVMYHGI-------ESQGGVSK-------GMFSS 686 Query: 1454 FYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1485 FYFI + + ++N+F+A+ +DN LT+D Sbjct: 687 FYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 721 Score = 125 bits (315), Expect = 3e-28 Identities = 161/728 (22%), Positives = 302/728 (41%), Gaps = 146/728 (20%) Query: 526 FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQ- 581 F ++++ + N + +A E + ++E D + +F E +K+ +LG Sbjct: 97 FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156 Query: 582 ---AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLS 638 +Y + +N D VV GIL T + + LR VR+LR K+ SL Sbjct: 157 HKGSYLRNGWNVMDFVVVLTGILATAGTD------FDLRTLRAVRVLRPLKLVSGIPSLQ 210 Query: 639 NLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF------------------- 679 ++ S++ ++ + + LLLF I++F+++G++ + GKF+ Sbjct: 211 VVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAEPVGDFPCGK 270 Query: 680 --------DEMQTRR---------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGP 722 + + R + FDN ++LTVFQ +T E W ++Y+ A G Sbjct: 271 EAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNT 330 Query: 723 SFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTA 782 +YFI L I G++ +LN+ L + A +E+ER + R Sbjct: 331 -----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERERVENRRAF 372 Query: 783 SPEKKQELVEKPAVG------ESKEEKIELKSITADGESP------PATKINMDDLQPNE 830 ++Q+ +E+ G +++E + + A+ +SP ATK + +DL E Sbjct: 373 LKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAE 432 Query: 831 NEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFR 890 ED VG P + LK E+S++F FR Sbjct: 433 EG-------------EDRFADLCAVGS---PFARASLKSGKT---ESSSYFR-RKEKMFR 472 Query: 891 LQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIIL 950 R+V F ++L + L+++ +A Q L A++VF +F E+ L Sbjct: 473 FFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTT-TLYFAEFVFLGLFLTEMSL 531 Query: 951 KMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRPLR 1007 KM YG L S+ R+ FN D V+ S+ I+ + + +LR LR+LR + Sbjct: 532 KM--YG--LGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFK 587 Query: 1008 AINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEA 1067 L+++V + ++++I +++ + L +FA +G+QLF G+ Sbjct: 588 VTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQF------------ 635 Query: 1068 ECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDS 1127 ++D E +FD AA++ +F + T E W ++Y I+S Sbjct: 636 -------NFQD-------------ETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIES 675 Query: 1128 HTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE--QEYKNCELDKN 1185 +++ S +FI+ + + ++N+F+ + E ++ + E N Sbjct: 676 QGGVSKGMFS-----SFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEMEEAAN 730 Query: 1186 QRQCVEYA 1193 Q+ ++ A Sbjct: 731 QKLALQKA 738 Score = 118 bits (296), Expect = 5e-26 Identities = 94/326 (28%), Positives = 164/326 (50%), Gaps = 24/326 (7%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILGNA 936 + F+FS +N R RI F +IL I+ + I LA E P + + L + Sbjct: 74 SLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDT 133 Query: 937 DYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKI 996 + F IF E +K+ A G HKGS+ RN +N++D +VV +++ + ++ Sbjct: 134 EPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA---TAGTDFDLRT 190 Query: 997 LRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLY 1056 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ MFA IG++ + GK + Sbjct: 191 LRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFH 250 Query: 1057 -TCSDSSKQTEAECKGNYITYKDGEV---DHPIIQPRSWENSKF---DFDNVLAAMMALF 1109 C +S T+AE G++ K+ + W F +FDN+L A++ +F Sbjct: 251 KACFPNS--TDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVF 308 Query: 1110 TVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTF 1169 T EGW ++LY + D+ G +N+ ++FI III +FFM+N+ +G + F Sbjct: 309 QCITMEGWTDILYNTNDA----AGNTWNW-----LYFIPLIIIGSFFMLNLVLGVLSGEF 359 Query: 1170 QEQGEQ-EYKNCELDKNQRQCVEYAL 1194 ++ E+ E + L ++Q +E L Sbjct: 360 AKERERVENRRAFLKLRRQQQIEREL 385 Score = 83.2 bits (204), Expect = 3e-15 Identities = 70/295 (23%), Positives = 130/295 (44%), Gaps = 66/295 (22%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N V L + D L+ + +F +F++E LK+IA+G+L Sbjct: 1472 PFEYFIMAMIALNTVVLMMKF---YDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVL 1528 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + + + ++ LR FR R Sbjct: 1529 ----NYFRDAWNVFDFVTVLGSITDILVTEIAETNNF---------INLSFLRLFRAARL 1575 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F Sbjct: 1576 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-------------- 1621 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 ++ +DD S +H NF F A++ +F+ T E Sbjct: 1622 GNIALDDDTSI-----------------------NRHN--NFRTFLQALMLLFRSATGEA 1656 Query: 365 WTDVLYWV--NDAV---------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ N A G D+ + YFV+ I + SF +LNL + V+ F Sbjct: 1657 WHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1711 Score = 69.3 bits (168), Expect = 4e-11 Identities = 65/301 (21%), Positives = 118/301 (39%), Gaps = 80/301 (26%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + G ++ F G+F E +K+IA F Sbjct: 97 FEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVF 156 Query: 1274 KPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRV 1333 Y + WNV DF++V+ I+ A + + R RV Sbjct: 157 HKGSYLRNGWNVMDFVVVLTGIL--------------------ATAGTDFDLRTLRAVRV 196 Query: 1334 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQV----FGKIALND 1389 +R +KL+S ++ +L + +K+ L + LL+ ++A+IG++ F K + Sbjct: 197 LRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPN 256 Query: 1390 TTEIN-------------------------------RNNNFQTFPQAVLLLFRCATGEAW 1418 +T+ NF A+L +F+C T E W Sbjct: 257 STDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVFQCITMEGW 316 Query: 1419 QDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDN 1478 DI+ N+ + G+++ YFI ++ +F ++NL + V+ Sbjct: 317 TDILY---------------NTNDA---AGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGE 358 Query: 1479 F 1479 F Sbjct: 359 F 359 >gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo sapiens] Length = 2506 Score = 767 bits (1981), Expect = 0.0 Identities = 401/869 (46%), Positives = 563/869 (64%), Gaps = 56/869 (6%) Query: 790 LVEKPAVGESKEEKIELKSITADGESPPATK--INMDDLQPNENEDKSPYPNPETTGEED 847 +V P+ ++ K K + PPA +N +Q N+N + P P E +E+ Sbjct: 1145 IVTNPSGTQTNSAKTARKPDHTTVDIPPACPPPLNHTVVQVNKNANPDPLPKKEEEKKEE 1204 Query: 848 EEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTIFTNLIL 907 EE+ GP+P MP S+ FI S+ N R CH I+N F IL Sbjct: 1205 EEDDRGEDGPKP--------------MPPYSSMFILSTTNPLRRLCHYILNLRYFEMCIL 1250 Query: 908 FFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRN 967 I +SSI+LAAEDPVQ + RN++L DYVFT +FT E+++KM G LH+G++ R+ Sbjct: 1251 MVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRD 1310 Query: 968 YFNILDLLVVSVSLISFGIQSSA----INVVKILRVLRVLRPLRAINRAKGLKHVVQCVF 1023 +NILD +VVS +L++F ++ IN +K LRVLRVLRPL+ I R LK V CV Sbjct: 1311 LWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVV 1370 Query: 1024 VAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDH 1083 +++ + NI+IV L F+FA + VQLFKGK + C+D SK+ E +C+G Y+ Y+ EV Sbjct: 1371 NSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDCRGKYLLYEKNEVK- 1429 Query: 1084 PIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEIS 1143 + R W+ +F +DNVL A++ LFTVST EGWP++L S+D+ E++GP YR+E+S Sbjct: 1430 --ARDREWKKYEFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMS 1487 Query: 1144 IFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYI 1203 IF+++Y ++ FF +NIFV +I+TFQEQG++ + L+KN+R C+++A+ A+PL R++ Sbjct: 1488 IFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHM 1547 Query: 1204 PKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGL 1261 P+N+ QY++W V S FEY + +I LNTI L M+ YG S ++ A+ + N++FT L Sbjct: 1548 PQNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSL 1607 Query: 1262 FTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENS 1321 F++E +LK++AF YF D WN+FDF+ V+GSI D++++E N+ Sbjct: 1608 FSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITDILVTEFG---------------NN 1652 Query: 1322 RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQV 1381 I+++F RLFR RL+KLL +G IR LLWTF++SF+ALPYV LLI MLFFIYA+IGMQV Sbjct: 1653 FINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQV 1712 Query: 1382 FGKIALN--------DTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAP 1433 FG I ++ D +I +NNF+TF QA++LLFR ATGEAW +IML+C+ GK C Sbjct: 1713 FGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKPC-- 1770 Query: 1434 ESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH 1493 NS CG+ FA FYF+SF LC+FL++NLFVAVIMDNF+YLTRD SILGPHH Sbjct: 1771 ---DKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHH 1827 Query: 1494 LDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSD 1553 LDE+ R+WAEYDP A GR+ +LD+ +LR + PPLG GK CP RVA KRL+ M++P+ D Sbjct: 1828 LDEYVRVWAEYDPAAWGRMPYLDMYQMLRHMSPPLGLGKKCPARVAYKRLLRMDLPVADD 1887 Query: 1554 GTVMFNATLFALVRTALRIKTE---GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGD 1610 TV FN+TL AL+RTAL IK + +Q + ELR + IW S K LD +V P Sbjct: 1888 NTVHFNSTLMALIRTALDIKIAKGGADKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKS 1947 Query: 1611 DEVTVGKFYATFLIQEYFRKFKKRKEQGL 1639 ++TVGK YA +I EY+R+ K +K Q + Sbjct: 1948 TDLTVGKIYAAMMIMEYYRQSKAKKLQAM 1976 Score = 671 bits (1731), Expect = 0.0 Identities = 383/826 (46%), Positives = 507/826 (61%), Gaps = 63/826 (7%) Query: 18 SNYGSPRPA-HANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTV 76 + +G PA + + AAAG+ GA S Q G G + Sbjct: 2 ARFGDEMPARYGGGGSGAAAGVVVGSGGGRGAGGSRQG-----------GQPGAQRMYKQ 50 Query: 77 SSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLT 133 S QR R Y P +Q T R +L + N +R+ I EW PFE +IL T Sbjct: 51 SMAQRARTMALYNPIPVRQNCLTVNR---SLFLFSEDNVVRKYAKKITEWPPFEYMILAT 107 Query: 134 IFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRN 193 I ANC+ LA+ P+DD + L+ E F+ IF EA +K+IA G FH +YLRN Sbjct: 108 IIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAFHKGSYLRN 167 Query: 194 GWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPS 253 GWN++DF++V+ G+ + + G FD++ LRA RVLRPL+LVSG+PS Sbjct: 168 GWNVMDFVVVLTGILATV----------------GTEFDLRTLRAVRVLRPLKLVSGIPS 211 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 LQVVL SI+KAM+PLL I LL+ F I+I+AIIGLE +MGK H TC+ +EG D+ E P Sbjct: 212 LQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCF-EEGTDDIQGES-P 269 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 +PC E R C NGT C+P W+GP +GIT FDN FA+LTVFQCITMEGWTD+LY N Sbjct: 270 APCGTEEP-ARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYNSN 328 Query: 374 DAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEED 433 DA G W W+YF+ LIIIGSFF+LNLVLGVLSGEF+KERE+ + R F KLR +QQ+E + Sbjct: 329 DASGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERE 388 Query: 434 LKGYLDWITQAEDIDPENEDEGMDEEKP----RNMSMPTSETESVNTENVAGGDIEGENC 489 L GY++WI++AE++ ++ ++ P R ++ S+T+ +N E + + Sbjct: 389 LNGYMEWISKAEEVILAEDETDGEQRHPFDALRRTTIKKSKTDLLNPEEAEDQLADIASV 448 Query: 490 G---ARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHY 546 G AR + + +K + S ++ + R R R VK+ FYW V+ LV LNTL +A HY Sbjct: 449 GSPFARASIKSAKLENSTFFHKKERRMRFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHY 508 Query: 547 NQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILV 606 NQP WL++ A L LF +EM +KMY LG + YF S FN FDC V+ G I E I Sbjct: 509 NQPEWLSDFLYYAEFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWA 568 Query: 607 ETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFS 666 K + GISVLR +RLLRIFK+T+YW SL NLV SLLNS++SI SLL LLFLFI++F+ Sbjct: 569 VIKPGTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFA 628 Query: 667 LLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPG 726 LLGMQLFGG+FNFDE T + FD FP +++TVFQILTGEDWN VMYDGI + GG G Sbjct: 629 LLGMQLFGGQFNFDE-GTPPTNFDTFPAAIMTVFQILTGEDWNEVMYDGIKSQGGVQ-GG 686 Query: 727 MLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERK---------- 776 M+ IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EEEE +K Sbjct: 687 MVFSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAANQKLALQKAKEVA 746 Query: 777 -----KLARTASPEKKQELVEKPA--VGESKEEKIELKSITADGES 815 A + K+Q+ +KPA V E + ++ +++ A E+ Sbjct: 747 EVSPLSAANMSIAVKEQQKNQKPAKSVWEQRTSEMRKQNLLASREA 792 Score = 202 bits (513), Expect = 4e-51 Identities = 176/705 (24%), Positives = 317/705 (44%), Gaps = 120/705 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 + K+++ + + P ++ L+ NP+RR C I+ + FE+ IL+ I + + Sbjct: 1199 EEKKEEEEDDRGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMCILMVIAMSSI 1258 Query: 140 ALAIYIPFPEDDSNATNSNLERV-EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLL 198 ALA P NA +N+ R +Y+F +FT E +K+I GL+ H AY R+ WN+L Sbjct: 1259 ALAAEDPV---QPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYFRDLWNIL 1315 Query: 199 DFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVL 258 DFI+V L + +K N +K+LR RVLRPL+ + +P L+ V Sbjct: 1316 DFIVVSGALVAFAFTGNSKGKDINT---------IKSLRVLRVLRPLKTIKRLPKLKAVF 1366 Query: 259 NSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGK-MHKTCYNQEGIADVPAEDDPSPCA 317 + ++ ++ + +I ++ + + I+A++ ++LF GK H T ++E D Sbjct: 1367 DCVVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFEKDC---------- 1416 Query: 318 LETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV- 376 G + V + K+ ++DN +A+LT+F T EGW VL DA Sbjct: 1417 --RGKYLLYEKNEVKARDREWKKYEF-HYDNVLWALLTLFTVSTGEGWPQVLKHSVDATF 1473 Query: 377 --------GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQ 428 R I++V ++ FF +N+ + ++ F ++ GD K+ E+ Sbjct: 1474 ENQGPSPGYRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KMMEEY 1524 Query: 429 QLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDIEGEN 488 LE++ + +D+ A KP MP Sbjct: 1525 SLEKNERACIDFAISA---------------KPLTRHMP--------------------- 1548 Query: 489 CGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQ 548 ++K S +R W V S F + ++ ++ LNT+ + + Y Sbjct: 1549 ----------QNKQSFQYRMWQ---------FVVSPPFEYTIMAMIALNTIVLMMKFYGA 1589 Query: 549 PNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVET 608 N +LF+ E +LK+ + G+ YF +N FD V G I + ILV Sbjct: 1590 SVAYENALRVFNIVFTSLFSLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITD-ILVTE 1648 Query: 609 KIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLL 668 + + +S LR R R+ K+ R ++ L+ + + S +++ + LL+ + I++++ Sbjct: 1649 FGNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAII 1708 Query: 669 GMQLFGG--------KFNFDEMQ-TRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAY 719 GMQ+FG + DE Q T + F F Q+L+ +F+ TGE W+++M + Sbjct: 1709 GMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGK 1768 Query: 720 GGPSFPGML--------VCIYFI-ILFICGNYILLNVFLAIAVDN 755 G+L YF+ +F+C ++++LN+F+A+ +DN Sbjct: 1769 PCDKNSGILTRECGNEFAYFYFVSFIFLC-SFLMLNLFVAVIMDN 1812 Score = 144 bits (364), Expect = 7e-34 Identities = 179/784 (22%), Positives = 325/784 (41%), Gaps = 160/784 (20%) Query: 480 AGGDIEGENCGARLAHRISKSKFSRYWRRWNRF-CRRKCRAAVKS-------NV------ 525 AGG +G GA+ ++ S ++ +R +N R+ C +S NV Sbjct: 33 AGGSRQGGQPGAQRMYKQSMAQRARTMALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAK 92 Query: 526 -------FYWLVIFLVFLNTLTIASEHY---NQPNWLTEVQDTANKALLALFTAEMLLKM 575 F ++++ + N + +A E + + ++E D + +F E +K+ Sbjct: 93 KITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKI 152 Query: 576 YSLGLQ----AYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKIT 631 +LG +Y + +N D VV GIL T+ E + LR VR+LR K+ Sbjct: 153 IALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTE------FDLRTLRAVRVLRPLKLV 206 Query: 632 RYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNF-------DEMQT 684 SL ++ S++ ++ + + LLLF I+IF+++G++ + GKF+ D++Q Sbjct: 207 SGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEEGTDDIQG 266 Query: 685 RR------------------------------STFDNFPQSLLTVFQILTGEDWNSVMYD 714 + FDN ++LTVFQ +T E W ++Y+ Sbjct: 267 ESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEGWTDLLYN 326 Query: 715 GIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKE 774 A G +YFI L I G++ +LN+ L + A +E+E Sbjct: 327 SNDASGNT-----WNWLYFIPLIIIGSFFMLNLVLGVLSGEFA-------------KERE 368 Query: 775 RKKLARTASPEKKQELVEKPAVGE----SKEEKIELKSITADGESP-PATKINMDDLQPN 829 R + R ++Q+ +E+ G SK E++ L DGE P + ++ Sbjct: 369 RVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDGEQRHPFDALRRTTIK-- 426 Query: 830 ENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRF 889 + K+ NPE ED+ VG P + +K + E S FF R Sbjct: 427 --KSKTDLLNPEEA--EDQLADIASVGS---PFARASIKSAKL---ENSTFF-HKKERRM 475 Query: 890 RLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEII 949 R R+V F +L + L+++ +A Q + + L A+++F +F E+ Sbjct: 476 RFYIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQ-PEWLSDFLYYAEFIFLGLFMSEMF 534 Query: 950 LKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISF---GIQSSAINVVKILRVLRVLRPL 1006 +KM G + + FN D V+ S+ I+ + +LR LR+LR Sbjct: 535 IKMYGLGT----RPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIF 590 Query: 1007 RAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTE 1066 + L+++V + ++++I +++ + L +FA +G+QLF G+ + + + T Sbjct: 591 KVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQ-FNFDEGTPPT- 648 Query: 1067 AECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSID 1126 +FD AA+M +F + T E W E++Y I Sbjct: 649 ------------------------------NFDTFPAAIMTVFQILTGEDWNEVMYDGIK 678 Query: 1127 SHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEYK 1178 S +G + SI+FI+ + + ++N+F+ + +T EQ E+E Sbjct: 679 SQGGVQGGMV-----FSIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEEAA 733 Query: 1179 NCEL 1182 N +L Sbjct: 734 NQKL 737 Score = 116 bits (291), Expect = 2e-25 Identities = 96/331 (29%), Positives = 163/331 (49%), Gaps = 33/331 (9%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILGNA 936 + F+FS +N R +I F +IL I+ + I LA E P + + L + Sbjct: 77 SLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDT 136 Query: 937 DYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI-SFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV ++ + G + ++ Sbjct: 137 EPYFIGIFCFEAGIKIIALGFAFHKGSYLRNGWNVMDFVVVLTGILATVGTEFD----LR 192 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ +FA IG++ + GK Sbjct: 193 TLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKF 252 Query: 1056 YT------CSDSSKQTEAEC--KGNYITYKDGEVDHPIIQPRSWE---NSKFDFDNVLAA 1104 +T D ++ A C + T +G P WE N FDN+L A Sbjct: 253 HTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPY-----WEGPNNGITQFDNILFA 307 Query: 1105 MMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGF 1164 ++ +F T EGW +LLY S D+ G +N+ ++FI III +FFM+N+ +G Sbjct: 308 VLTVFQCITMEGWTDLLYNSNDA----SGNTWNW-----LYFIPLIIIGSFFMLNLVLGV 358 Query: 1165 VIVTFQEQGEQ-EYKNCELDKNQRQCVEYAL 1194 + F ++ E+ E + L ++Q +E L Sbjct: 359 LSGEFAKERERVENRRAFLKLRRQQQIEREL 389 Score = 114 bits (286), Expect = 8e-25 Identities = 77/294 (26%), Positives = 138/294 (46%), Gaps = 42/294 (14%) Query: 1195 KARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNIL 1254 K R +R YI + +V + F + + L+ LNT+C+A+ HY Q + Sbjct: 471 KERRMRFYIRR---------MVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYA 521 Query: 1255 NMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPS 1314 +F GLF EM +K+ + YF +N FD ++IGSI +VI + P Sbjct: 522 EFIFLGLFMSEMFIKMYGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKP--------- 572 Query: 1315 MNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIY 1374 + I+ R R++R+ K+ +R L+ + + S +++ + L+ + ++ Sbjct: 573 -----GTSFGISVLRALRLLRIFKVTKYWASLRNLVVSLLNSMKSIISLLFLLFLFIVVF 627 Query: 1375 AVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPE 1434 A++GMQ+FG + E NF TFP A++ +F+ TGE W ++M Sbjct: 628 ALLGMQLFG--GQFNFDEGTPPTNFDTFPAAIMTVFQILTGEDWNEVMY----------- 674 Query: 1435 SEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1485 ++G G F++ YFI + + ++N+F+A+ +DN LT+D Sbjct: 675 --DGIKSQGGVQGGMVFSI-YFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 725 Score = 82.0 bits (201), Expect = 6e-15 Identities = 73/297 (24%), Positives = 130/297 (43%), Gaps = 62/297 (20%) Query: 125 PFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 PFE I+ I N + L + S A + L +F +F++E LKV+A+G+L Sbjct: 1566 PFEYTIMAMIALNTIVLMMKF---YGASVAYENALRVFNIVFTSLFSLECVLKVMAFGIL 1622 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DF+ V+ + ++ + G N + ++ LR FR R Sbjct: 1623 ----NYFRDAWNIFDFVTVLGSITDILVTEF----GNNFI-------NLSFLRLFRAARL 1667 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F GI Sbjct: 1668 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF---------GNIGI 1718 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 DV ED T H NF F A++ +F+ T E Sbjct: 1719 -DVEDEDSDEDEFQITEH---------------------NNFRTFFQALMLLFRSATGEA 1756 Query: 365 WTDVLY-------------WVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEF 408 W +++ + G ++ + YFV+ I + SF +LNL + V+ F Sbjct: 1757 WHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLNLFVAVIMDNF 1813 Score = 67.8 bits (164), Expect = 1e-10 Identities = 70/302 (23%), Positives = 120/302 (39%), Gaps = 81/302 (26%) Query: 1221 FEYLMFVLILLNTICLAMQHY---GQSCLFKIAMNILNMLFTGLFTVEMILKLIA----F 1273 FEY++ I+ N I LA++ + ++ F G+F E +K+IA F Sbjct: 100 FEYMILATIIANCIVLALEQHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFAF 159 Query: 1274 KPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLFRV 1333 Y + WNV DF++V+ I+ + +E + R RV Sbjct: 160 HKGSYLRNGWNVMDFVVVLTGILATVGTE--------------------FDLRTLRAVRV 199 Query: 1334 MRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF-GKI------- 1385 +R +KL+S ++ +L + +K+ L + LL+ I+A+IG++ + GK Sbjct: 200 LRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAILIFAIIGLEFYMGKFHTTCFEE 259 Query: 1386 ----------ALNDTTEINR---------------NNNFQTFPQ---AVLLLFRCATGEA 1417 A T E R NN F AVL +F+C T E Sbjct: 260 GTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGITQFDNILFAVLTVFQCITMEG 319 Query: 1418 WQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMD 1477 W D++ NS + G+++ YFI ++ +F ++NL + V+ Sbjct: 320 WTDLLY---------------NSNDAS---GNTWNWLYFIPLIIIGSFFMLNLVLGVLSG 361 Query: 1478 NF 1479 F Sbjct: 362 EF 363 >gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E subunit [Homo sapiens] Length = 2270 Score = 749 bits (1935), Expect = 0.0 Identities = 390/833 (46%), Positives = 546/833 (65%), Gaps = 38/833 (4%) Query: 833 DKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQ 892 D P E EDEEE E + + +E M S+ FIFS+ N R Sbjct: 1093 DGEASPLKEAEIREDEEEVEKKKQKKEK-------RETGKAMVPHSSMFIFSTTNPIRRA 1145 Query: 893 CHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLEIILKM 952 CH IVN F IL I SSI+LAAEDPV S RN +L DYVFT +FT E+++KM Sbjct: 1146 CHYIVNLRYFEMCILLVIAASSIALAAEDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKM 1205 Query: 953 TAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA-------INVVKILRVLRVLRP 1005 G L GS+ R+ +NILD +VV +L++F + ++ I +K LRVLRVLRP Sbjct: 1206 IDQGLILQDGSYFRDLWNILDFVVVVGALVAFALANALGTNKGRDIKTIKSLRVLRVLRP 1265 Query: 1006 LRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQT 1065 L+ I R LK V CV +++ + NI+IV L F+FA I VQLFKGK + C+DSSK T Sbjct: 1266 LKTIKRLPKLKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKDT 1325 Query: 1066 EAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSI 1125 E EC GNY+ ++ +++ ++ R W+ +F +DN++ A++ LFTVST EGWP++L S+ Sbjct: 1326 EKECIGNYVDHEKNKME---VKGREWKRHEFHYDNIIWALLTLFTVSTGEGWPQVLQHSV 1382 Query: 1126 DSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKN 1185 D ED+GP + R+E+SIF+++Y ++ FF +NIFV +I+TFQEQG++ + C L+KN Sbjct: 1383 DVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLEKN 1442 Query: 1186 QRQCVEYALKARPLRRYIPKNQH--QYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQ 1243 +R C+++A+ A+PL RY+P+N+H QY+VW+ V S FEY + +I LNT+ L M++Y Sbjct: 1443 ERACIDFAISAKPLTRYMPQNRHTFQYRVWHFVVSPSFEYTIMAMIALNTVVLMMKYYSA 1502 Query: 1244 SCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSET 1303 C +++A+ LN+ FT +F++E +LK+IAF YF D WN+FDF+ VIGSI ++IL+++ Sbjct: 1503 PCTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEIILTDS 1562 Query: 1304 NPAEHTQCSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYV 1363 S +++F +LFR RL+KLL +G IR LLWTF++SF+ALPYV Sbjct: 1563 KLVN------------TSGFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYV 1610 Query: 1364 ALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIML 1423 LLI MLFFIYA+IGMQVFG I L++ + INR+NNF++F +++LLFR ATGEAWQ+IML Sbjct: 1611 CLLIAMLFFIYAIIGMQVFGNIKLDEESHINRHNNFRSFFGSLMLLFRSATGEAWQEIML 1670 Query: 1424 ACMPGKKCAPESE-PSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYL 1482 +C+ K C P++ PS E E CG+ A YF+SF C+FL++NLFVAVIMDNF+YL Sbjct: 1671 SCLGEKGCEPDTTAPSGQNENER-CGTDLAYVYFVSFIFFCSFLMLNLFVAVIMDNFEYL 1729 Query: 1483 TRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKR 1542 TRD SILGPHHLDEF R+WAEYD A GRI + ++ +L + PPLG GK CP +VA KR Sbjct: 1730 TRDSSILGPHHLDEFVRVWAEYDRAACGRIHYTEMYEMLTLMSPPLGLGKRCPSKVAYKR 1789 Query: 1543 LVSMNMPLNSDGTVMFNATLFALVRTALRIKTE---GNLEQANEELRAIIKKIWKRTSMK 1599 LV MNMP+ D TV F +TL AL+RTAL IK + +Q + EL+ IW S K Sbjct: 1790 LVLMNMPVAEDMTVHFTSTLMALIRTALDIKIAKGGADRQQLDSELQKETLAIWPHLSQK 1849 Query: 1600 LLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQ 1652 +LD +VP ++TVGK YA +I +Y+++ K +K++ + Q+NA Q Sbjct: 1850 MLDLLVPMPKASDLTVGKIYAAMMIMDYYKQSKVKKQRQQL--EEQKNAPMFQ 1900 Score = 630 bits (1626), Expect = e-180 Identities = 359/754 (47%), Positives = 468/754 (62%), Gaps = 35/754 (4%) Query: 60 RQAKLMGSAGNATISTVSSTQRKRQQ--YGK-PKKQGSTTATRPPRALLCLTLKNPIRRA 116 RQ + ++G A + QR R Y P +Q T R +L N +R+ Sbjct: 25 RQGTPVPASGQAAAYKQTKAQRARTMALYNPIPVRQNCFTVNR---SLFIFGEDNIVRKY 81 Query: 117 CISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFL 176 +++W PFE +IL TI ANC+ LA+ PEDD + LE+ E F+ IF EA + Sbjct: 82 AKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGI 141 Query: 177 KVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKAL 236 K++A G +FH +YLRNGWN++DFI+V+ G+ AT N D++ L Sbjct: 142 KIVALGFIFHKGSYLRNGWNVMDFIVVLSGIL------ATAGTHFNT------HVDLRTL 189 Query: 237 RAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHK 296 RA RVLRPL+LVSG+PSLQ+VL SI+KAMVPLL I LL+ F I+++AIIGLE + GK+H+ Sbjct: 190 RAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHR 249 Query: 297 TCY-NQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLT 355 C+ N GI + D P PC ++ C G CK W GP GIT FDN FA+LT Sbjct: 250 ACFMNNSGILE--GFDPPHPCGVQG-----CPAGYECKD-WIGPNDGITQFDNILFAVLT 301 Query: 356 VFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKA 415 VFQCITMEGWT VLY NDA+G W W+YF+ LIIIGSFFVLNLVLGVLSGEF+KERE+ Sbjct: 302 VFQCITMEGWTTVLYNTNDALGATWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERERV 361 Query: 416 KARGDFQKLREKQQLEEDLKGYLDWITQAEDI--DPENEDEGMDE-EKPRNMSMPTSETE 472 + R F KLR +QQ+E +L GY WI +AE++ EN++ G E R ++ S TE Sbjct: 362 ENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTE 421 Query: 473 SVNTENVAGGDIEGENCGARLAHRISKSKFS---RYWRRWNRFCRRKCRAAVKSNVFYWL 529 ++ ++ ++ + G LA KS Y+R R R R VKS VFYW+ Sbjct: 422 AMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRISIRHMVKSQVFYWI 481 Query: 530 VIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFN 589 V+ LV LNT +A H+NQP WLT + A L LF EM LKMY +G + YF S FN Sbjct: 482 VLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRLYFHSSFN 541 Query: 590 RFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVR 649 FD V G I E + + + GISVLR +RLLRIFKIT+YW SL NLV SL++S++ Sbjct: 542 CFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSSMK 601 Query: 650 SIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWN 709 SI SLL LLFLFI++F+LLGMQLFGG+FNF++ T + FD FP +++TVFQILTGEDWN Sbjct: 602 SIISLLFLLFLFIVVFALLGMQLFGGRFNFND-GTPSANFDTFPAAIMTVFQILTGEDWN 660 Query: 710 SVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEE 769 VMY+GI + GG S GM IYFI+L + GNY LLNVFLAIAVDNLA+A+ LT ++EE Sbjct: 661 EVMYNGIRSQGGVS-SGMWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEE 719 Query: 770 EEEKERKKLARTASPEKKQELVEKPAVGESKEEK 803 EE +K + A P++ + + Sbjct: 720 EEAFNQKHALQKAKEVSPMSAPNMPSIERDRRRR 753 Score = 220 bits (561), Expect = 1e-56 Identities = 185/707 (26%), Positives = 329/707 (46%), Gaps = 124/707 (17%) Query: 80 QRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCV 139 ++K+Q K +K+ + A P ++ + NPIRRAC IV + FE+ ILL I A+ + Sbjct: 1112 EKKKQ---KKEKRETGKAMVPHSSMFIFSTTNPIRRACHYIVNLRYFEMCILLVIAASSI 1168 Query: 140 ALAIYIPFPEDDSNATNSNLERV----EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGW 195 ALA +D TNS +V +Y+F +FT E +K+I GL+ +Y R+ W Sbjct: 1169 ALAA------EDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKMIDQGLILQDGSYFRDLW 1222 Query: 196 NLLDFIIVVVGLFSAILEQATKADGANALG-GKGAGF-DVKALRAFRVLRPLRLVSGVPS 253 N+LDF++VV L + L ANALG KG +K+LR RVLRPL+ + +P Sbjct: 1223 NILDFVVVVGALVAFAL--------ANALGTNKGRDIKTIKSLRVLRVLRPLKTIKRLPK 1274 Query: 254 LQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDP 313 L+ V + ++ ++ + +I ++ + I+A+I ++LF GK C + ++D Sbjct: 1275 LKAVFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFF-YCTDS-------SKDTE 1326 Query: 314 SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVN 373 C G+ + + G + +H ++DN +A+LT+F T EGW VL Sbjct: 1327 KEC---IGNYVDHEKNKMEVKGREWKRHEF-HYDNIIWALLTLFTVSTGEGWPQVLQHSV 1382 Query: 374 DAVGRD---------WPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKL 424 D D I++V ++ FF +N+ + ++ F ++ GD K+ Sbjct: 1383 DVTEEDRGPSRSNRMEMSIFYVVYFVVFPFFFVNIFVALIIITFQEQ-------GD--KM 1433 Query: 425 REKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVAGGDI 484 E+ LE++ + +D+ A KP MP Sbjct: 1434 MEECSLEKNERACIDFAISA---------------KPLTRYMP----------------- 1461 Query: 485 EGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASE 544 +++ + +R W+ V S F + ++ ++ LNT+ + + Sbjct: 1462 --------------QNRHTFQYRVWH---------FVVSPSFEYTIMAMIALNTVVLMMK 1498 Query: 545 HYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETI 604 +Y+ P N A +F+ E +LK+ + G YF +N FD V G I E I Sbjct: 1499 YYSAPCTYELALKYLNIAFTMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEII 1558 Query: 605 LVETKIMSPLG--ISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFI 662 L ++K+++ G +S L+ R R+ K+ R ++ L+ + + S +++ + LL+ + Sbjct: 1559 LTDSKLVNTSGFNMSFLKLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLF 1618 Query: 663 IIFSLLGMQLFGG-KFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG- 720 I++++GMQ+FG K + + R + F +F SL+ +F+ TGE W +M + G Sbjct: 1619 FIYAIIGMQVFGNIKLDEESHINRHNNFRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGC 1678 Query: 721 -----GPSFPGM-------LVCIYFIILFICGNYILLNVFLAIAVDN 755 PS L +YF+ ++++LN+F+A+ +DN Sbjct: 1679 EPDTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMDN 1725 Score = 201 bits (510), Expect = 8e-51 Identities = 173/698 (24%), Positives = 307/698 (43%), Gaps = 141/698 (20%) Query: 879 AFFIFSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAED--PVQHTSFRNHILGNA 936 + FIF +N R ++++ F +IL I+ + I LA E P + + L Sbjct: 68 SLFIFGEDNIVRKYAKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKT 127 Query: 937 DYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVV-SVSLISFGIQSSAINVVK 995 + F IF E +K+ A G HKGS+ RN +N++D +VV S L + G + ++ Sbjct: 128 EPYFIGIFCFEAGIKIVALGFIFHKGSYLRNGWNVMDFIVVLSGILATAGTHFNTHVDLR 187 Query: 996 ILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKL 1055 LR +RVLRPL+ ++ L+ V++ + A+ + I ++ MFA IG++ + GKL Sbjct: 188 TLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKL 247 Query: 1056 YTCSDSSKQTEAECKGNYITYKDG-EVDHPI--------IQPRSW---ENSKFDFDNVLA 1103 + C N +G + HP + + W + FDN+L Sbjct: 248 HRA----------CFMNNSGILEGFDPPHPCGVQGCPAGYECKDWIGPNDGITQFDNILF 297 Query: 1104 AMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVG 1163 A++ +F T EGW +LY + D+ G +N+ ++FI III +FF++N+ +G Sbjct: 298 AVLTVFQCITMEGWTTVLYNTNDA----LGATWNW-----LYFIPLIIIGSFFVLNLVLG 348 Query: 1164 ------------------FVIVTFQEQGEQEYKNCEL----------------------- 1182 F+ + Q+Q E+E Sbjct: 349 VLSGEFAKERERVENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALE 408 Query: 1183 -----------------DKNQRQCVEYALKARPLRRYIPKN---------QHQYK----- 1211 D + CV+ + PL R K+ +H+ + Sbjct: 409 VLRRATIKRSRTEAMTRDSSDEHCVDISSVGTPLARASIKSAKVDGVSYFRHKERLLRIS 468 Query: 1212 VWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLI 1271 + ++V S F +++ L+ LNT C+A+ H+ Q + LF GLF +EM LK+ Sbjct: 469 IRHMVKSQVFYWIVLSLVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMY 528 Query: 1272 AFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLF 1331 P+ YF +N FDF + +GSI +V+ + P + I+ R Sbjct: 529 GMGPRLYFHSSFNCFDFGVTVGSIFEVVWAIFRP--------------GTSFGISVLRAL 574 Query: 1332 RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVF-GKIALNDT 1390 R++R+ K+ +R L+ + + S +++ + L+ + ++A++GMQ+F G+ ND Sbjct: 575 RLLRIFKITKYWASLRNLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGRFNFNDG 634 Query: 1391 TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS 1450 T + NF TFP A++ +F+ TGE W ++M + ++G G Sbjct: 635 TP---SANFDTFPAAIMTVFQILTGEDWNEVMYNGI-------------RSQGGVSSG-M 677 Query: 1451 FAVFYFISFYMLCAFLIINLFVAVIMDNF---DYLTRD 1485 ++ YFI + + ++N+F+A+ +DN LT+D Sbjct: 678 WSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKD 715 Score = 133 bits (335), Expect = 2e-30 Identities = 155/731 (21%), Positives = 302/731 (41%), Gaps = 140/731 (19%) Query: 526 FYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKA---LLALFTAEMLLKMYSLGL-- 580 F ++++ + N + +A E + + T + K + +F E +K+ +LG Sbjct: 91 FEYMILATIIANCIVLALEQHLPEDDKTPMSRRLEKTEPYFIGIFCFEAGIKIVALGFIF 150 Query: 581 --QAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLS 638 +Y + +N D VV GIL T T + + + LR VR+LR K+ SL Sbjct: 151 HKGSYLRNGWNVMDFIVVLSGILAT--AGTHFNTHVDLRTLRAVRVLRPLKLVSGIPSLQ 208 Query: 639 NLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFN-------------FDEMQTR 685 ++ S++ ++ + + LLLF I++F+++G++ + GK + FD Sbjct: 209 IVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYSGKLHRACFMNNSGILEGFDPPHPC 268 Query: 686 R--------------------STFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFP 725 + FDN ++LTVFQ +T E W +V+Y+ A G Sbjct: 269 GVQGCPAGYECKDWIGPNDGITQFDNILFAVLTVFQCITMEGWTTVLYNTNDALGAT--- 325 Query: 726 GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASPE 785 +YFI L I G++ +LN+ L + A +E+ER + R Sbjct: 326 --WNWLYFIPLIIIGSFFVLNLVLGVLSGEFA-------------KERERVENRRAFMKL 370 Query: 786 KKQELVEKPAVGE----SKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNPE 841 ++Q+ +E+ G K E++ L + + + ++ + E + Sbjct: 371 RRQQQIERELNGYRAWIDKAEEVMLAEENKNAGTSALEVLRRATIKRSRTEAMT------ 424 Query: 842 TTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDTI 901 + +E + + PL+ +K V + R+ +V + Sbjct: 425 ---RDSSDEHCVDISSVGTPLARASIKSAKVD----GVSYFRHKERLLRISIRHMVKSQV 477 Query: 902 FTNLILFFILLSSISLAAEDPVQHTS--FRNHILGNADYVFTSIFTLEIILKMTAYGAFL 959 F ++L + L++ +A V H + H+L A+++F +F LE+ LKM G L Sbjct: 478 FYWIVLSLVALNTACVAI---VHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRL 534 Query: 960 HKGSFCRNYFNILD--LLVVSVSLISFGIQSSAINV-VKILRVLRVLRPLRAINRAKGLK 1016 + + FN D + V S+ + + I + + +LR LR+LR + L+ Sbjct: 535 ----YFHSSFNCFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLR 590 Query: 1017 HVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITY 1076 ++V + ++++I +++ + L +FA +G+QLF G+ + Sbjct: 591 NLVVSLMSSMKSIISLLFLLFLFIVVFALLGMQLFGGRF-------------------NF 631 Query: 1077 KDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIY 1136 DG +FD AA+M +F + T E W E++Y I S ++ Sbjct: 632 NDG-------------TPSANFDTFPAAIMTVFQILTGEDWNEVMYNGIRSQGGVSSGMW 678 Query: 1137 NYRVEISIFFIIYIIIIAFFMMNIFVGFVI--------VTFQEQGEQEYKNCELDKNQRQ 1188 + +I+FI+ + + ++N+F+ + +T EQ E+E NQ+ Sbjct: 679 S-----AIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEEEE------AFNQKH 727 Query: 1189 CVEYALKARPL 1199 ++ A + P+ Sbjct: 728 ALQKAKEVSPM 738 Score = 81.3 bits (199), Expect = 1e-14 Identities = 72/302 (23%), Positives = 131/302 (43%), Gaps = 74/302 (24%) Query: 126 FEIIILLTIFANCVALAI-YIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLL 184 FE I+ I N V L + Y P A L+ + F ++F++E LKVIA+G L Sbjct: 1480 FEYTIMAMIALNTVVLMMKYYSAPCTYELA----LKYLNIAFTMVFSLECVLKVIAFGFL 1535 Query: 185 FHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRP 244 Y R+ WN+ DFI V+ + IL + + + GF++ L+ FR R Sbjct: 1536 ----NYFRDTWNIFDFITVIGSITEIILTDSKLVNTS--------GFNMSFLKLFRAARL 1583 Query: 245 LRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGI 304 ++L+ +++++L + +++ L ++ LL+ + IYAIIG+++F Sbjct: 1584 IKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVF-------------- 1629 Query: 305 ADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEG 364 ++ ++ E+ R NF +F +++ +F+ T E Sbjct: 1630 GNIKLDE-------ESHINRH------------------NNFRSFFGSLMLLFRSATGEA 1664 Query: 365 WTDVLYWV------------------NDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSG 406 W +++ N+ G D ++YFV+ I SF +LNL + V+ Sbjct: 1665 WQEIMLSCLGEKGCEPDTTAPSGQNENERCGTDLAYVYFVSFIFFCSFLMLNLFVAVIMD 1724 Query: 407 EF 408 F Sbjct: 1725 NF 1726 >gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo sapiens] Length = 1977 Score = 335 bits (860), Expect = 2e-91 Identities = 255/856 (29%), Positives = 433/856 (50%), Gaps = 79/856 (9%) Query: 754 DNLADAESLTSAQKEEEEEKERKKLARTASPEKK--------QELVEKPAV--------G 797 +N +L K KE+ K++ S K Q + P++ G Sbjct: 1024 ENYISNHTLAEMSKGHNFLKEKDKISGFGSSVDKHLMEDSDGQSFIHNPSLTVTVPIAPG 1083 Query: 798 ESKEEKIELKSITADGESPPATKINMDDLQPNE-NEDKSPYPNPETTGEEDEEEPEMPVG 856 ES E + + +++D +S +K+ ++ +E + +P P GEE E EP Sbjct: 1084 ESDLENMNAEELSSDSDSE-YSKVRLNRSSSSECSTVDNPLPGE---GEEAEAEPMNSDE 1139 Query: 857 PRPRPLSELHLKEKAVPMPEASAFFIFSSNNRF----RLQCHRIVNDTIFTNLILFFILL 912 P E + V I S + R C++IV + F + I+ ILL Sbjct: 1140 P------EACFTDGCVRRFSCCQVNIESGKGKIWWNIRKTCYKIVEHSWFESFIVLMILL 1193 Query: 913 SSISLAAEDP-VQHTSFRNHILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNI 971 SS +LA ED ++ IL AD +FT IF LE++LK AYG ++ N + Sbjct: 1194 SSGALAFEDIYIERKKTIKIILEYADKIFTYIFILEMLLKWIAYGY----KTYFTNAWCW 1249 Query: 972 LDLLVVSVSLISFGIQS---SAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRT 1028 LD L+V VSL++ + S + +K LR LR LRPLRA++R +G++ VV + AI + Sbjct: 1250 LDFLIVDVSLVTLVANTLGYSDLGPIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPS 1309 Query: 1029 IGNIVIVTTLLQFMFACIGVQLFKGKLYTC---SDSSKQTEAECKGNYITYKDGEVDHPI 1085 I N+++V + +F+ +GV LF GK Y C +D S+ ++ + V + Sbjct: 1310 IMNVLLVCLIFWLIFSIMGVNLFAGKFYECINTTDGSRFPASQVPNRSECFALMNVSQNV 1369 Query: 1086 IQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIF 1145 W+N K +FDNV ++L V+TF+GW ++Y ++DS DK P Y Y + + I+ Sbjct: 1370 ----RWKNLKVNFDNVGLGYLSLLQVATFKGWTIIMYAAVDSVNVDKQPKYEYSLYMYIY 1425 Query: 1146 FIIYIIIIAFFMMNIFVGFVIVTFQEQ----GEQEYKNCELDKNQRQCVEYALKARPLRR 1201 F+++II +FF +N+F+G +I F +Q G Q+ E K ++ +P ++ Sbjct: 1426 FVVFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMTEEQKKYYNAMKKLGSKKP-QK 1484 Query: 1202 YIPK--NQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFT 1259 IP+ N+ Q ++ +V + F+ + VLI LN + + ++ GQS + +N++F Sbjct: 1485 PIPRPGNKIQGCIFDLVTNQAFDISIMVLICLNMVTMMVEKEGQSQHMTEVLYWINVVFI 1544 Query: 1260 GLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEE 1319 LFT E +LKLI+ + YF+ WN+FDF++VI SI+ + L++ E SP++ Sbjct: 1545 ILFTGECVLKLISLR-HYYFTVGWNIFDFVVVIISIVGMFLADL--IETYFVSPTL---- 1597 Query: 1320 NSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGM 1379 RL R+ R+++L+ +GIRTLL+ + S AL + LL+ ++ FIYA+ GM Sbjct: 1598 -----FRVIRLARIGRILRLVKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGM 1652 Query: 1380 QVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGK--KCAPES-E 1436 F + D IN NF+TF +++ LF+ T W ++ + K C P+ Sbjct: 1653 SNFAYVKKED--GINDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPKKVH 1710 Query: 1437 PSNSTEGETPCGS-SFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRD-WSILGPHHL 1494 P +S EG+ CG+ S +FYF+S+ ++ +++N+++AVI++NF T + L Sbjct: 1711 PGSSVEGD--CGNPSVGIFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDF 1768 Query: 1495 DEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDG 1554 + F +W ++DP+A I+ + + PPL K P++V +L++M++P+ S Sbjct: 1769 EMFYEVWEKFDPDATQFIEFSKLSDFAAALDPPLLIAK--PNKV---QLIAMDLPMVSGD 1823 Query: 1555 TVMFNATLFALVRTAL 1570 + LFA + L Sbjct: 1824 RIHCLDILFAFTKRVL 1839 Score = 174 bits (441), Expect = 8e-43 Identities = 176/696 (25%), Positives = 293/696 (42%), Gaps = 132/696 (18%) Query: 113 IRRACISIVEWKPFEIIILLTIFANCVALA---IYIPFPEDDSNATNSNLERVEYLFLII 169 IR+ C IVE FE I+L I + ALA IYI + LE + +F I Sbjct: 1170 IRKTCYKIVEHSWFESFIVLMILLSSGALAFEDIYI----ERKKTIKIILEYADKIFTYI 1225 Query: 170 FTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGA 229 F +E LK IAYG Y N W LDF+IV V L + + AN LG Sbjct: 1226 FILEMLLKWIAYGY----KTYFTNAWCWLDFLIVDVSLVTLV---------ANTLGYSDL 1272 Query: 230 GFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLEL 289 G +K+LR R LRPLR +S ++VV+N++I A+ ++++ L+ L +I++I+G+ L Sbjct: 1273 G-PIKSLRTLRALRPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNL 1331 Query: 290 FMGKMHKTCYNQEGIADVPAEDDP--SPCALETGHGRQCQNGTVCKPGWDGPKHGITNFD 347 F GK ++ C N + PA P S C + + W K NFD Sbjct: 1332 FAGKFYE-CINTTDGSRFPASQVPNRSECFALMNVSQNVR--------WKNLK---VNFD 1379 Query: 348 NFAFAMLTVFQCITMEGWTDVLYWVNDAVGRD---------WPWIYFVTLIIIGSFFVLN 398 N L++ Q T +GWT ++Y D+V D + +IYFV II GSFF LN Sbjct: 1380 NVGLGYLSLLQVATFKGWTIIMYAAVDSVNVDKQPKYEYSLYMYIYFVVFIIFGSFFTLN 1439 Query: 399 LVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDE 458 L +GV+ F+++++K + D E+++ +K Q P N+ +G Sbjct: 1440 LFIGVIIDNFNQQKKKLGGQ-DIFMTEEQKKYYNAMKKLGSKKPQKPIPRPGNKIQGCIF 1498 Query: 459 EKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCR 518 + N + S + C + + K S++ Sbjct: 1499 DLVTNQAFDISIMVLI--------------CLNMVTMMVEKEGQSQH------------- 1531 Query: 519 AAVKSNVFYWLVIFLVFLNT------LTIASEHYNQPNWLTEVQDTANKALLALFTAEML 572 + V YW+ + + L T L +Y W +++ +F A++ Sbjct: 1532 ---MTEVLYWINVVFIILFTGECVLKLISLRHYYFTVGWNIFDFVVVIISIVGMFLADL- 1587 Query: 573 LKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITR 632 ++ YFVS P V+R R+ RI ++ + Sbjct: 1588 -------IETYFVS--------------------------PTLFRVIRLARIGRILRLVK 1614 Query: 633 YWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNF 692 + L+ +L+ S+ ++ ++ LLLFL + I+++ GM F D + F+ F Sbjct: 1615 GAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKKEDGIND-MFNFETF 1673 Query: 693 PQSLLTVFQILTGEDWNSVM----------YDGIMAYGGPSFPG-----MLVCIYFIILF 737 S++ +FQI T W+ ++ D + G S G + YF+ Sbjct: 1674 GNSMICLFQITTSAGWDGLLAPILNSKPPDCDPKKVHPGSSVEGDCGNPSVGIFYFVSYI 1733 Query: 738 ICGNYILLNVFLAIAVDNLADA-ESLTSAQKEEEEE 772 I +++N+++A+ ++N + A E T E++ E Sbjct: 1734 IISFLVVVNMYIAVILENFSVATEESTEPLSEDDFE 1769 Score = 160 bits (404), Expect = 2e-38 Identities = 106/355 (29%), Positives = 180/355 (50%), Gaps = 50/355 (14%) Query: 103 ALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERV 162 AL L+ +P+RR I I+ F ++I+ TI NC+ + + P P+ N V Sbjct: 105 ALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMNNP-PDWTKN--------V 155 Query: 163 EYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGAN 222 EY F I+T E+ +K++A G +LR+ WN LDF+++V + + Sbjct: 156 EYTFTGIYTFESLVKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVN--------- 206 Query: 223 ALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIY 282 LG +V ALR FRVLR L+ +S +P L+ ++ ++I+++ L + +L +F + ++ Sbjct: 207 -LG------NVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVF 259 Query: 283 AIIGLELFMGKMHKTCY-----NQEGIADV-----------------PAEDDPSPCALET 320 A+IGL+LFMG + C+ N E + + D C T Sbjct: 260 ALIGLQLFMGNLKHKCFRNSLENNETLESIMNTLESEEDFRKYFYYLEGSKDALLCGFST 319 Query: 321 GHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDW 380 G QC G C P +G T+FD F++A L +F+ +T + W ++ A G+ + Sbjct: 320 DSG-QCPEGYTCVKIGRNPDYGYTSFDTFSWAFLALFRLMTQDYWENLYQQTLRAAGKTY 378 Query: 381 PWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLK 435 I+FV +I +GSF+++NL+L V++ + +E+ +A QK E QQ+ + LK Sbjct: 379 -MIFFVVVIFLGSFYLINLILAVVAMAY-EEQNQANIEEAKQKELEFQQMLDRLK 431 Score = 130 bits (328), Expect = 1e-29 Identities = 100/324 (30%), Positives = 168/324 (51%), Gaps = 30/324 (9%) Query: 492 RLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFL-VFLNTLTIASEHYNQPN 550 R AH+ S YW ++ +KC + + F L I + + LNTL +A EH+ Sbjct: 705 RFAHKFLIWNCSPYWIKF-----KKCIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTE 759 Query: 551 WLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKI 610 V N +F AEM+LK+ ++ YF +N FD +V ++E L + + Sbjct: 760 EFKNVLAIGNLVFTGIFAAEMVLKLIAMDPYEYFQVGWNIFDSLIVTLSLVELFLADVE- 818 Query: 611 MSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGM 670 G+SVLR RLLR+FK+ + W +L+ L+ + NSV ++ +L L+L + + IF+++GM Sbjct: 819 ----GLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGM 874 Query: 671 QLFGGKFN------FDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSF 724 QLFG + D+ R ++F S L VF++L GE W M+D + G Sbjct: 875 QLFGKSYKECVCKINDDCTLPRWHMNDFFHSFLIVFRVLCGE-WIETMWDCMEVAG---- 929 Query: 725 PGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASP 784 M + +Y +++ I GN ++LN+FLA+ + + + +++LT+ EE+ + ++A T Sbjct: 930 QAMCLIVYMMVMVI-GNLVVLNLFLALLLSSFS-SDNLTAI--EEDPDANNLQIAVTRIK 985 Query: 785 E----KKQELVEKPAVGESKEEKI 804 + KQ L E SK+ KI Sbjct: 986 KGINYVKQTLREFILKAFSKKPKI 1009 Score = 118 bits (296), Expect = 5e-26 Identities = 77/277 (27%), Positives = 139/277 (50%), Gaps = 51/277 (18%) Query: 1212 VWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLI 1271 ++++V + + + + I+LNT+ +AM+H+ + FK + I N++FTG+F EM+LKLI Sbjct: 726 IYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKNVLAIGNLVFTGIFAAEMVLKLI 785 Query: 1272 AFKPKGYFSDPWNVFDFLIVIGSIIDVILSETNPAEHTQCSPSMNAEENSRISITFFRLF 1331 A P YF WN+FD LIV S++++ L++ ++ R F Sbjct: 786 AMDPYEYFQVGWNIFDSLIVTLSLVELFLADVE-------------------GLSVLRSF 826 Query: 1332 RVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGK------I 1385 R++R+ KL + L+ S AL + L++ ++ FI+AV+GMQ+FGK Sbjct: 827 RLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVC 886 Query: 1386 ALNDTTEINR---NNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTE 1442 +ND + R N+ F +F L++FR GE W + M CM Sbjct: 887 KINDDCTLPRWHMNDFFHSF----LIVFRVLCGE-WIETMWDCM---------------- 925 Query: 1443 GETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNF 1479 G + + ++ ++ +++NLF+A+++ +F Sbjct: 926 --EVAGQAMCLIVYMMVMVIGNLVVLNLFLALLLSSF 960 Score = 102 bits (253), Expect = 5e-21 Identities = 79/325 (24%), Positives = 148/325 (45%), Gaps = 42/325 (12%) Query: 509 WNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASE--HYNQPNWLTEVQDTANKALLAL 566 WN R+ C V+ + F ++ ++ L++ +A E + + + + + A+K + Sbjct: 1168 WN--IRKTCYKIVEHSWFESFIVLMILLSSGALAFEDIYIERKKTIKIILEYADKIFTYI 1225 Query: 567 FTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLG-ISVLRCVRLL 625 F EMLLK + G + YF + + D F++ L T++ T S LG I LR +R L Sbjct: 1226 FILEMLLKWIAYGYKTYFTNAWCWLD-FLIVDVSLVTLVANTLGYSDLGPIKSLRTLRAL 1284 Query: 626 RIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF-------- 677 R + + + +V +L+ ++ SI ++LL+ +F +IFS++G+ LF GKF Sbjct: 1285 RPLRALSRFEGMRVVVNALIGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYECINTTD 1344 Query: 678 ----------NFDEM------------QTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDG 715 N E + + FDN L++ Q+ T + W +MY Sbjct: 1345 GSRFPASQVPNRSECFALMNVSQNVRWKNLKVNFDNVGLGYLSLLQVATFKGWTIIMYAA 1404 Query: 716 IMAYGGPSFP----GMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQK--EE 769 + + P + + IYF++ I G++ LN+F+ + +DN + Q Sbjct: 1405 VDSVNVDKQPKYEYSLYMYIYFVVFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDIFMT 1464 Query: 770 EEEKERKKLARTASPEKKQELVEKP 794 EE+K+ + +K Q+ + +P Sbjct: 1465 EEQKKYYNAMKKLGSKKPQKPIPRP 1489 Score = 100 bits (250), Expect = 1e-20 Identities = 96/407 (23%), Positives = 180/407 (44%), Gaps = 70/407 (17%) Query: 830 ENEDKSPYPNPETTGEEDEEEP----EMPVGPRPRPLSELHL----KEKAVPMPEASAFF 881 + +D P P + E ++ P ++P G PL +L K+ + + + F Sbjct: 39 KKDDDEEAPKPSSDLEAGKQLPFIYGDIPPGMVSEPLEDLDPYYADKKTFIVLNKGKTIF 98 Query: 882 IFSSN---------NRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHI 932 F++ + R +I+ ++F+ LI+ IL + I + +P T Sbjct: 99 RFNATPALYMLSPFSPLRRISIKILVHSLFSMLIMCTILTNCIFMTMNNPPDWTK----- 153 Query: 933 LGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAIN 992 N +Y FT I+T E ++K+ A G + + +F R+ +N LD +V+ + ++ + + Sbjct: 154 --NVEYTFTGIYTFESLVKILARGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVN---LG 208 Query: 993 VVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFK 1052 V LR RVLR L+ I+ GLK +V + +++ + +++I+T +FA IG+QLF Sbjct: 209 NVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFM 268 Query: 1053 GKL-YTCSDSSKQTEAECKG------------NYITYKDGEVDHPIIQ--------PRSW 1091 G L + C +S + + Y Y +G D + P + Sbjct: 269 GNLKHKCFRNSLENNETLESIMNTLESEEDFRKYFYYLEGSKDALLCGFSTDSGQCPEGY 328 Query: 1092 ENSKF---------DFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEI 1142 K FD A +ALF + T + W L +++ + G Y Sbjct: 329 TCVKIGRNPDYGYTSFDTFSWAFLALFRLMTQDYWENLYQQTLRA----AGKTY------ 378 Query: 1143 SIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE---QEYKNCELDKNQ 1186 IFF++ I + +F+++N+ + V + ++EQ + +E K EL+ Q Sbjct: 379 MIFFVVVIFLGSFYLINLILAVVAMAYEEQNQANIEEAKQKELEFQQ 425 Score = 86.3 bits (212), Expect = 3e-16 Identities = 95/353 (26%), Positives = 151/353 (42%), Gaps = 48/353 (13%) Query: 79 TQRKRQQYGKPKKQGSTTATRP-PRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFAN 137 T+ +++ Y KK GS +P PR N I+ +V + F+I I++ I N Sbjct: 1464 TEEQKKYYNAMKKLGSKKPQKPIPRP------GNKIQGCIFDLVTNQAFDISIMVLICLN 1517 Query: 138 CVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNL 197 V + + E S L + +F+I+FT E LK+I+ + Y GWN+ Sbjct: 1518 MVTMMVE---KEGQSQHMTEVLYWINVVFIILFTGECVLKLISLR-----HYYFTVGWNI 1569 Query: 198 LDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVV 257 DF++V++ + L AD F V +R R+ R LRLV G ++ + Sbjct: 1570 FDFVVVIISIVGMFL-----ADLIETYFVSPTLFRV--IRLARIGRILRLVKGAKGIRTL 1622 Query: 258 LNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCA 317 L +++ ++ L +I LL+ V+ IYAI G+ F ++GI D+ Sbjct: 1623 LFALMMSLPALFNIGLLLFLVMFIYAIFGMSNF-----AYVKKEDGINDM--------FN 1669 Query: 318 LET-GHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAV 376 ET G+ C GWDG I N V ++EG N +V Sbjct: 1670 FETFGNSMICLFQITTSAGWDGLLAPILNSKPPDCDPKKVHPGSSVEGDCG-----NPSV 1724 Query: 377 GRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFS---KEREKAKARGDFQKLRE 426 G YFV+ III V+N+ + V+ FS +E + + DF+ E Sbjct: 1725 G----IFYFVSYIIISFLVVVNMYIAVILENFSVATEESTEPLSEDDFEMFYE 1773 Score = 84.0 bits (206), Expect = 1e-15 Identities = 75/299 (25%), Positives = 132/299 (44%), Gaps = 60/299 (20%) Query: 115 RACISIVEWKPF-EIIILLTIFANCVALAI-YIPFPEDDSNATNSNLERVEYLFLIIFTV 172 + CI + PF ++ I + I N + +A+ + P E+ N L +F IF Sbjct: 723 KKCIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKNV----LAIGNLVFTGIFAA 778 Query: 173 EAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFD 232 E LK+IA P Y + GWN+ D +IV + L L Sbjct: 779 EMVLKLIA----MDPYEYFQVGWNIFDSLIVTLSLVELFLADVE---------------G 819 Query: 233 VKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMG 292 + LR+FR+LR +L P+L +++ I ++ L ++ L++ ++ I+A++G++LF G Sbjct: 820 LSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-G 878 Query: 293 KMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFA 352 K +K C DD C L P W + ++F + Sbjct: 879 KSYKECV-------CKINDD---CTL---------------PRW--------HMNDFFHS 905 Query: 353 MLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKE 411 L VF+ + E W + ++ + G+ I ++ +++IG+ VLNL L +L FS + Sbjct: 906 FLIVFRVLCGE-WIETMWDCMEVAGQAMCLIVYMMVMVIGNLVVLNLFLALLLSSFSSD 963 Score = 70.1 bits (170), Expect = 2e-11 Identities = 47/169 (27%), Positives = 89/169 (52%), Gaps = 8/169 (4%) Query: 888 RFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILGNADYVFTSIFTLE 947 +F+ + IV D I I+L+++ +A E F+N +L + VFT IF E Sbjct: 721 KFKKCIYFIVMDPFVDLAITICIVLNTLFMAMEHHPMTEEFKN-VLAIGNLVFTGIFAAE 779 Query: 948 IILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLR 1007 ++LK+ A + + + +NI D L+V++SL+ + + + +LR R+LR + Sbjct: 780 MVLKLIAMDPY----EYFQVGWNIFDSLIVTLSLVELFLAD--VEGLSVLRSFRLLRVFK 833 Query: 1008 AINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLY 1056 L +++ + ++ +GN+ +V ++ F+FA +G+QLF GK Y Sbjct: 834 LAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLF-GKSY 881 Score = 62.4 bits (150), Expect = 5e-09 Identities = 80/383 (20%), Positives = 148/383 (38%), Gaps = 75/383 (19%) Query: 524 NVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKM----YSLG 579 ++F L++ + N + + N P+W V+ T ++T E L+K+ + +G Sbjct: 126 SLFSMLIMCTILTNCIFMTMN--NPPDWTKNVEYT----FTGIYTFESLVKILARGFCVG 179 Query: 580 LQAYFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSN 639 + +N D V+ L T+ ++ +S LR R+LR K L Sbjct: 180 EFTFLRDPWNWLDFVVIVFAYL------TEFVNLGNVSALRTFRVLRALKTISVIPGLKT 233 Query: 640 LVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKF----------NFDEMQTRRSTF 689 +V +L+ SV+ ++ +++L + +F+L+G+QLF G N + +++ +T Sbjct: 234 IVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLKHKCFRNSLENNETLESIMNTL 293 Query: 690 DN-------------FPQSLLTVFQILTG---EDWNSVMYDGIMAYGGPSF--------- 724 ++ +LL F +G E + V YG SF Sbjct: 294 ESEEDFRKYFYYLEGSKDALLCGFSTDSGQCPEGYTCVKIGRNPDYGYTSFDTFSWAFLA 353 Query: 725 --------------------PGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTS 764 G I+F+++ G++ L+N+ LA+ E Sbjct: 354 LFRLMTQDYWENLYQQTLRAAGKTYMIFFVVVIFLGSFYLINLILAVVA---MAYEEQNQ 410 Query: 765 AQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPAT-KINM 823 A EE ++KE + +K+QE E A ++ I I ES T K++ Sbjct: 411 ANIEEAKQKELEFQQMLDRLKKEQEEAEAIAAAAAEYTSIRRSRIMGLSESSSETSKLSS 470 Query: 824 DDLQPNENEDKSPYPNPETTGEE 846 + N K ++GEE Sbjct: 471 KSAKERRNRRKKKNQKKLSSGEE 493 Score = 59.3 bits (142), Expect = 4e-08 Identities = 60/285 (21%), Positives = 111/285 (38%), Gaps = 109/285 (38%) Query: 1258 FTGLFTVEMILKLIAFKPKGY-------FSDPWNVFDFLIVIGSIIDVILSETNPAEHTQ 1310 FTG++T E ++K++A +G+ DPWN DF++++ + + ++ N Sbjct: 159 FTGIYTFESLVKILA---RGFCVGEFTFLRDPWNWLDFVVIVFAYLTEFVNLGN------ 209 Query: 1311 CSPSMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML 1370 ++ R FRV+R +K +S G++T++ I+S + L V +L V Sbjct: 210 --------------VSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFC 255 Query: 1371 FFIYAVIGMQVF----------GKIALNDTTE---------------------------- 1392 ++A+IG+Q+F + N+T E Sbjct: 256 LSVFALIGLQLFMGNLKHKCFRNSLENNETLESIMNTLESEEDFRKYFYYLEGSKDALLC 315 Query: 1393 -----------------INRN-----NNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK 1430 I RN +F TF A L LFR T + W+++ + Sbjct: 316 GFSTDSGQCPEGYTCVKIGRNPDYGYTSFDTFSWAFLALFRLMTQDYWENLYQQTL---- 371 Query: 1431 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVI 1475 G ++ +F+ + + L +F +INL +AV+ Sbjct: 372 --------------RAAGKTYMIFFVVVIF-LGSFYLINLILAVV 401 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.137 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 82,195,663 Number of Sequences: 37866 Number of extensions: 3969350 Number of successful extensions: 26018 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 122 Number of HSP's successfully gapped in prelim test: 264 Number of HSP's that attempted gapping in prelim test: 19313 Number of HSP's gapped (non-prelim): 2882 length of query: 2138 length of database: 18,247,518 effective HSP length: 118 effective length of query: 2020 effective length of database: 13,779,330 effective search space: 27834246600 effective search space used: 27834246600 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.