Guide to the Human Genome
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Search of human proteins with 189571621

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189571621 HRAS-like suppressor 3 [Homo sapiens]
         (162 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189571621 HRAS-like suppressor 3 [Homo sapiens]                    325   1e-89
gi|189571618 HRAS-like suppressor 3 [Homo sapiens]                    325   1e-89
gi|8923526 HRAS-like suppressor 2 [Homo sapiens]                      223   6e-59
gi|149588791 retinoic acid receptor responder (tazarotene induce...   165   1e-41
gi|9966859 HRAS-like suppressor [Homo sapiens]                        148   2e-36
gi|16905367 HRAS-like suppressor family, member 5 isoform 1 [Hom...   138   2e-33
gi|226491950 HRAS-like suppressor family, member 5 isoform 2 [Ho...   138   2e-33
gi|226528146 HRAS-like suppressor family, member 5 isoform 3 [Ho...   108   3e-24
gi|46249410 lecithin retinol acyltransferase [Homo sapiens]            55   3e-08
gi|28557798 family with sequence similarity 84, member B [Homo s...    43   1e-04
gi|21553329 family with sequence similarity 84, member A [Homo s...    34   0.048
gi|7949031 cytochrome P450, family 2, subfamily B, polypeptide 6...    31   0.41 
gi|58218986 thymocyte selection pathway associated [Homo sapiens]      30   1.2  
gi|217416343 fibrosin-like 1 [Homo sapiens]                            27   5.9  
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]           27   7.7  
gi|25777602 proteasome 26S non-ATPase subunit 2 [Homo sapiens]         27   7.7  

>gi|189571621 HRAS-like suppressor 3 [Homo sapiens]
          Length = 162

 Score =  325 bits (833), Expect = 1e-89
 Identities = 162/162 (100%), Positives = 162/162 (100%)

Query: 1   MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV 60
           MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
Sbjct: 1   MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV 60

Query: 61  KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL 120
           KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
Sbjct: 61  KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL 120

Query: 121 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ 162
           RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
Sbjct: 121 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ 162


>gi|189571618 HRAS-like suppressor 3 [Homo sapiens]
          Length = 162

 Score =  325 bits (833), Expect = 1e-89
 Identities = 162/162 (100%), Positives = 162/162 (100%)

Query: 1   MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV 60
           MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV
Sbjct: 1   MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV 60

Query: 61  KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL 120
           KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL
Sbjct: 61  KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL 120

Query: 121 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ 162
           RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ
Sbjct: 121 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ 162


>gi|8923526 HRAS-like suppressor 2 [Homo sapiens]
          Length = 162

 Score =  223 bits (568), Expect = 6e-59
 Identities = 109/157 (69%), Positives = 130/157 (82%)

Query: 6   PEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELL 65
           P P+ GDLIEI R  Y HWAIYVGDGYVVHLAP SE+AGAGAASV+SALT+KAIVKKELL
Sbjct: 6   PRPRLGDLIEISRFGYAHWAIYVGDGYVVHLAPASEIAGAGAASVLSALTNKAIVKKELL 65

Query: 66  YDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYGVA 125
             VAG D Y+VNNKHDD+Y+PLP +KI++RAEELVGQE+ Y LTS+NCEHFVN LRYGV+
Sbjct: 66  SVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVS 125

Query: 126 RSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ 162
           RSDQV   +    VA   LAA SL+G++ +R+KR++Q
Sbjct: 126 RSDQVTGAVTTVGVAAGLLAAASLVGILLARSKRERQ 162


>gi|149588791 retinoic acid receptor responder (tazarotene induced)
           3 [Homo sapiens]
          Length = 164

 Score =  165 bits (418), Expect = 1e-41
 Identities = 83/162 (51%), Positives = 107/162 (66%), Gaps = 1/162 (0%)

Query: 1   MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV 60
           M +P  EPKPGDLIEIFR  Y HWA+Y+GDGYV+HLAPPSE  GAG++SV S L++ A V
Sbjct: 1   MASPHQEPKPGDLIEIFRLGYEHWALYIGDGYVIHLAPPSEYPGAGSSSVFSVLSNSAEV 60

Query: 61  KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL 120
           K+E L DV G   Y+VNN  D +Y P P   II  A+E+VGQ++ Y + S NCEHFV +L
Sbjct: 61  KRERLEDVVGGCCYRVNNSLDHEYQPRPVEVIISSAKEMVGQKMKYSIVSRNCEHFVTQL 120

Query: 121 RYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ 162
           RYG +R  QV    +   VA   L  + + G  F+  + QK+
Sbjct: 121 RYGKSRCKQVEKAKVEVGVA-TALGILVVAGCSFAIRRYQKK 161


>gi|9966859 HRAS-like suppressor [Homo sapiens]
          Length = 168

 Score =  148 bits (374), Expect = 2e-36
 Identities = 72/154 (46%), Positives = 99/154 (64%), Gaps = 2/154 (1%)

Query: 8   PKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELLYD 67
           P PGDLIE+FRP Y+HWA+Y+GDGYV+++AP   +  A   S  S  + KA+VK +LL D
Sbjct: 15  PCPGDLIEVFRPGYQHWALYLGDGYVINIAPVDGIP-ASFTSAKSVFSSKALVKMQLLKD 73

Query: 68  VAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYGVARS 127
           V G+D Y++NNK+D+ Y PLP  +II+R+E ++GQEV Y L   NCEHFV  LRYG   S
Sbjct: 74  VVGNDTYRINNKYDETYPPLPVEEIIKRSEFVIGQEVAYNLLVNNCEHFVTLLRYGEGVS 133

Query: 128 DQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQK 161
           +Q    I         +   S +G +F + +R K
Sbjct: 134 EQANRAISTVEFVTAAVGVFSFLG-LFPKGQRAK 166


>gi|16905367 HRAS-like suppressor family, member 5 isoform 1 [Homo
           sapiens]
          Length = 279

 Score =  138 bits (347), Expect = 2e-33
 Identities = 75/143 (52%), Positives = 92/143 (64%), Gaps = 3/143 (2%)

Query: 6   PEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELL 65
           P P+PGDLIEIFR  Y HWAIYV D  VVHLAPPSE    G  S+ S  +++A+VK   L
Sbjct: 128 PRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVG--SITSIFSNRAVVKYSRL 185

Query: 66  YDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYGVA 125
            DV     ++VNNK D  Y PLP  KIIQR +++V + V Y L   NCEHFVN LRYGV 
Sbjct: 186 EDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNGLRYGVP 245

Query: 126 RSDQVRDVII-AASVAGMGLAAM 147
           RS QV   ++  A  AG  ++A+
Sbjct: 246 RSQQVEHALMEGAKAAGAVISAV 268


>gi|226491950 HRAS-like suppressor family, member 5 isoform 2 [Homo
           sapiens]
          Length = 269

 Score =  138 bits (347), Expect = 2e-33
 Identities = 75/143 (52%), Positives = 92/143 (64%), Gaps = 3/143 (2%)

Query: 6   PEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELL 65
           P P+PGDLIEIFR  Y HWAIYV D  VVHLAPPSE    G  S+ S  +++A+VK   L
Sbjct: 118 PRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVG--SITSIFSNRAVVKYSRL 175

Query: 66  YDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYGVA 125
            DV     ++VNNK D  Y PLP  KIIQR +++V + V Y L   NCEHFVN LRYGV 
Sbjct: 176 EDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNCEHFVNGLRYGVP 235

Query: 126 RSDQVRDVII-AASVAGMGLAAM 147
           RS QV   ++  A  AG  ++A+
Sbjct: 236 RSQQVEHALMEGAKAAGAVISAV 258


>gi|226528146 HRAS-like suppressor family, member 5 isoform 3 [Homo
           sapiens]
          Length = 253

 Score =  108 bits (269), Expect = 3e-24
 Identities = 57/108 (52%), Positives = 69/108 (63%), Gaps = 2/108 (1%)

Query: 6   PEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELL 65
           P P+PGDLIEIFR  Y HWAIYV D  VVHLAPPSE    G  S+ S  +++A+VK   L
Sbjct: 128 PRPRPGDLIEIFRIGYEHWAIYVEDDCVVHLAPPSEEFEVG--SITSIFSNRAVVKYSRL 185

Query: 66  YDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENC 113
            DV     ++VNNK D  Y PLP  KIIQR +++V + V Y L   NC
Sbjct: 186 EDVLHGCSWKVNNKLDGTYLPLPVDKIIQRTKKMVNKIVQYSLIEGNC 233


>gi|46249410 lecithin retinol acyltransferase [Homo sapiens]
          Length = 230

 Score = 54.7 bits (130), Expect = 3e-08
 Identities = 43/166 (25%), Positives = 74/166 (44%), Gaps = 24/166 (14%)

Query: 11  GDLIEIFRPFYRHWAIYVGDGYVVHLAPP-----------SEVAGAGAASVMSALTDKAI 59
           GD++E+ R    H+ IY+GD  V H+ P            ++   +    ++  +   A 
Sbjct: 48  GDVLEVPRTHLTHYGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVAS 107

Query: 60  VKKELLYDVAGSDKYQVNNKHDD-KYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVN 118
           ++ + + D A      VN+  +  +   L   ++ +RAE+L+G    Y L   NCEHFV 
Sbjct: 108 IRVDTVEDFAYGANILVNHLDESLQKKALLNEEVARRAEKLLG-FTPYSLLWNNCEHFVT 166

Query: 119 ELRYGVARSDQ-----------VRDVIIAASVAGMGLAAMSLIGVM 153
             RYG   S Q           +RD     + A +GLA++   G++
Sbjct: 167 YCRYGTPISPQSDKFCETVKIIIRDQRSVLASAVLGLASIVCTGLV 212


>gi|28557798 family with sequence similarity 84, member B [Homo
           sapiens]
          Length = 310

 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 38/116 (32%), Positives = 54/116 (46%), Gaps = 22/116 (18%)

Query: 9   KPGDLIE-IFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELLYD 67
           KPGDL+E + +  Y HWA+YVG+  VVHL             + S LTD +         
Sbjct: 117 KPGDLVEFVSQAQYPHWAVYVGNFQVVHL--------HRLEVINSFLTDAS--------- 159

Query: 68  VAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYG 123
             G     VN+ +  +Y PL  S +++ A   VG +   +L+  N E F    RYG
Sbjct: 160 -QGRRGRVVNDLY--RYKPLSSSAVVRNALAHVGAKE-RELSWRNSESFAAWCRYG 211


>gi|21553329 family with sequence similarity 84, member A [Homo
           sapiens]
          Length = 292

 Score = 34.3 bits (77), Expect = 0.048
 Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 29/123 (23%)

Query: 9   KPGDLIEIF--RPFYR------HWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIV 60
           +PGDL+E+   +P         HWA+YVG G ++HL                    +  +
Sbjct: 121 EPGDLLELLWLQPAPEPPAPAPHWAVYVGGGQIIHL-------------------HQGEI 161

Query: 61  KKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNEL 120
           +++ LY+   ++  +V N    +Y PL    ++Q A   +G +   ++   N E F    
Sbjct: 162 RQDSLYEAGAANVGRVVNSW-YRYRPLVAELVVQNACGHLGLK-SEEICWTNSESFAAWC 219

Query: 121 RYG 123
           R+G
Sbjct: 220 RFG 222


>gi|7949031 cytochrome P450, family 2, subfamily B, polypeptide 6
          [Homo sapiens]
          Length = 491

 Score = 31.2 bits (69), Expect = 0.41
 Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 6/60 (10%)

Query: 4  PIPEPKPGDLIE-----IFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKA 58
          P P P  G+L++     + + F R    Y GD + VHL P   V   G  ++  AL DKA
Sbjct: 34 PRPLPLLGNLLQMDRRGLLKSFLRFREKY-GDVFTVHLGPRPVVMLCGVEAIREALVDKA 92


>gi|58218986 thymocyte selection pathway associated [Homo sapiens]
          Length = 641

 Score = 29.6 bits (65), Expect = 1.2
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 6/67 (8%)

Query: 25  AIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQ----VNNKH 80
           ++ VGD ++VH +  +EV   G   V++ L  + I+KK   Y+ A    Y     V   H
Sbjct: 382 SVSVGDQFLVHQSETTEVLCEGIKKVVNVLACEKILKKS--YEAALLPLYMEGGFVEVIH 439

Query: 81  DDKYSPL 87
           D K  P+
Sbjct: 440 DKKQYPI 446


>gi|217416343 fibrosin-like 1 [Homo sapiens]
          Length = 1045

 Score = 27.3 bits (59), Expect = 5.9
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 42  VAGAG-AASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELV 100
           V+G G +    S   DKA V  E L+   G+DK     K + K  P+P    ++R+ EL 
Sbjct: 199 VSGRGYSCDSESGPDDKASVGSEKLF-APGTDKGPALEKSEAKAGPVPKVSGLERSRELS 257

Query: 101 GQEVL 105
            +  L
Sbjct: 258 AESFL 262


>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
          Length = 463

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 10/28 (35%), Positives = 16/28 (57%)

Query: 6   PEPKPGDLIEIFRPFYRHWAIYVGDGYV 33
           P+ +PG  + +  P+Y  WA  V  G+V
Sbjct: 73  PDGEPGSFVNVSCPWYLPWASSVPQGHV 100


>gi|25777602 proteasome 26S non-ATPase subunit 2 [Homo sapiens]
          Length = 908

 Score = 26.9 bits (58), Expect = 7.7
 Identities = 20/67 (29%), Positives = 37/67 (55%), Gaps = 4/67 (5%)

Query: 40  SEVAGAGAASVMSALTD--KAIVKKE--LLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQR 95
           S+VA AG  +V+ +  D    I+ K   +LY +  + + ++    D++  PLP S  + +
Sbjct: 789 SQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQ 848

Query: 96  AEELVGQ 102
           A ++VGQ
Sbjct: 849 AVDVVGQ 855


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,054,243
Number of Sequences: 37866
Number of extensions: 251813
Number of successful extensions: 545
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 526
Number of HSP's gapped (non-prelim): 16
length of query: 162
length of database: 18,247,518
effective HSP length: 94
effective length of query: 68
effective length of database: 14,688,114
effective search space: 998791752
effective search space used: 998791752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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