Guide to the Human Genome
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Search of human proteins with 189095241

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189095241 potassium voltage-gated channel, Isk-related
family, member 1 [Homo sapiens]
         (129 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189095241 potassium voltage-gated channel, Isk-related family...   263   3e-71
gi|189095239 potassium voltage-gated channel, Isk-related family...   263   3e-71
gi|189095237 potassium voltage-gated channel, Isk-related family...   263   3e-71
gi|60218915 potassium voltage-gated channel, Isk-related family,...   263   3e-71
gi|27436978 potassium voltage-gated channel, Isk-related family,...    55   2e-08
gi|154448884 potassium voltage-gated channel, Isk-related family...    41   3e-04
gi|4885443 potassium voltage-gated channel, Isk-related family, ...    37   0.006
gi|6912442 potassium voltage-gated channel, Isk-related family, ...    33   0.081
gi|239747139 PREDICTED: hypothetical protein XP_002343922 [Homo ...    29   1.2  
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ...    28   2.6  
gi|113410972 PREDICTED: hypothetical protein [Homo sapiens]            28   2.6  
gi|193788732 calcium channel, voltage-dependent, L type, alpha 1...    26   7.6  
gi|193788724 calcium channel, voltage-dependent, L type, alpha 1...    26   7.6  
gi|193788720 calcium channel, voltage-dependent, L type, alpha 1...    26   7.6  
gi|193788544 calcium channel, voltage-dependent, L type, alpha 1...    26   7.6  
gi|193788540 calcium channel, voltage-dependent, L type, alpha 1...    26   7.6  
gi|193788538 calcium channel, voltage-dependent, L type, alpha 1...    26   7.6  
gi|193794830 calcium channel, voltage-dependent, L type, alpha 1...    26   7.6  
gi|193794828 calcium channel, voltage-dependent, L type, alpha 1...    26   7.6  
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  26   7.6  
gi|148225857 G protein-coupled receptor 34 [Homo sapiens]              26   9.9  
gi|4885319 G protein-coupled receptor 34 [Homo sapiens]                26   9.9  

>gi|189095241 potassium voltage-gated channel, Isk-related family,
           member 1 [Homo sapiens]
          Length = 129

 Score =  263 bits (672), Expect = 3e-71
 Identities = 129/129 (100%), Positives = 129/129 (100%)

Query: 1   MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 60
           MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG
Sbjct: 1   MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 60

Query: 61  IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 120
           IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT
Sbjct: 61  IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 120

Query: 121 HLPETKPSP 129
           HLPETKPSP
Sbjct: 121 HLPETKPSP 129


>gi|189095239 potassium voltage-gated channel, Isk-related family,
           member 1 [Homo sapiens]
          Length = 129

 Score =  263 bits (672), Expect = 3e-71
 Identities = 129/129 (100%), Positives = 129/129 (100%)

Query: 1   MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 60
           MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG
Sbjct: 1   MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 60

Query: 61  IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 120
           IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT
Sbjct: 61  IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 120

Query: 121 HLPETKPSP 129
           HLPETKPSP
Sbjct: 121 HLPETKPSP 129


>gi|189095237 potassium voltage-gated channel, Isk-related family,
           member 1 [Homo sapiens]
          Length = 129

 Score =  263 bits (672), Expect = 3e-71
 Identities = 129/129 (100%), Positives = 129/129 (100%)

Query: 1   MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 60
           MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG
Sbjct: 1   MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 60

Query: 61  IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 120
           IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT
Sbjct: 61  IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 120

Query: 121 HLPETKPSP 129
           HLPETKPSP
Sbjct: 121 HLPETKPSP 129


>gi|60218915 potassium voltage-gated channel, Isk-related family,
           member 1 [Homo sapiens]
          Length = 129

 Score =  263 bits (672), Expect = 3e-71
 Identities = 129/129 (100%), Positives = 129/129 (100%)

Query: 1   MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 60
           MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG
Sbjct: 1   MILSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLG 60

Query: 61  IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 120
           IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT
Sbjct: 61  IMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNT 120

Query: 121 HLPETKPSP 129
           HLPETKPSP
Sbjct: 121 HLPETKPSP 129


>gi|27436978 potassium voltage-gated channel, Isk-related family,
           member 2 [Homo sapiens]
          Length = 123

 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 23/51 (45%), Positives = 38/51 (74%), Gaps = 1/51 (1%)

Query: 45  LYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVYIESDAWQEKDKAYV 95
           LY+++++G F F  + I++S ++SK+ EHSNDP++ YI  D WQEK K+ +
Sbjct: 51  LYLMVMIGMFSFIIVAILVSTVKSKRREHSNDPYHQYIVED-WQEKYKSQI 100


>gi|154448884 potassium voltage-gated channel, Isk-related family,
          member 4 [Homo sapiens]
          Length = 170

 Score = 40.8 bits (94), Expect = 3e-04
 Identities = 19/51 (37%), Positives = 31/51 (60%), Gaps = 1/51 (1%)

Query: 43 EALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVYIESD-AWQEKDK 92
          E  Y+L+V+ F+G F +GIML Y++SK+ E  +    +Y + +  W E  K
Sbjct: 35 EYFYILVVMSFYGIFLIGIMLGYMKSKRREKKSSLLLLYKDEERLWGEAMK 85


>gi|4885443 potassium voltage-gated channel, Isk-related family,
          member 3 [Homo sapiens]
          Length = 103

 Score = 36.6 bits (83), Expect = 0.006
 Identities = 14/40 (35%), Positives = 27/40 (67%)

Query: 45 LYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVYIES 84
          +Y+L V+  F      ++L Y RS+K++  +DP++VYI++
Sbjct: 59 MYILFVMFLFAVTVGSLILGYTRSRKVDKRSDPYHVYIKN 98


>gi|6912442 potassium voltage-gated channel, Isk-related family,
          member 1-like [Homo sapiens]
          Length = 142

 Score = 32.7 bits (73), Expect = 0.081
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 33 RSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSND 76
          R   S+ G    LY+L+++ F+     G++L+Y RS+KL  + D
Sbjct: 49 REVTSAKGDDAYLYILLIMIFYACLAGGLILAYTRSRKLVEAKD 92


>gi|239747139 PREDICTED: hypothetical protein XP_002343922 [Homo
           sapiens]
          Length = 182

 Score = 28.9 bits (63), Expect = 1.2
 Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 5/59 (8%)

Query: 61  IMLSYIRSKKLEHSNDPFNVYIESDAWQEKD---KAYVQARVLESYRSCYVVENHLAIE 116
           ++ SY+R K  EHS      Y+     + ++   + YV+ R L+   S  V+E+HL ++
Sbjct: 51  VLESYVREKHSEHSRSALESYVRDKHSEPRNIVLETYVRDRHLDPRSS--VLESHLRVK 107



 Score = 26.9 bits (58), Expect = 4.5
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 6/58 (10%)

Query: 61  IMLSYIRSKKLEHSN---DPFNVYIESDAWQEKDKAYVQARVLESYRSC---YVVENH 112
           ++ SY+R+K  EHS    + +  Y  SD      ++YV+ +  E  RS    YV + H
Sbjct: 19  VLESYVRNKHSEHSRSVLESYRRYKHSDPHSSVLESYVREKHSEHSRSALESYVRDKH 76


>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
           [Homo sapiens]
          Length = 918

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 15/63 (23%), Positives = 33/63 (52%)

Query: 3   LSNTTAVTPFLTKLWQETVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIM 62
           LS+ T+ T ++ ++   T + G +       +P+ + G++EA+ V + L F     LG++
Sbjct: 579 LSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVL 638

Query: 63  LSY 65
             +
Sbjct: 639 FCF 641


>gi|113410972 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 182

 Score = 27.7 bits (60), Expect = 2.6
 Identities = 16/59 (27%), Positives = 31/59 (52%), Gaps = 5/59 (8%)

Query: 61  IMLSYIRSKKLEHSNDPFNVYIESDAWQEKD---KAYVQARVLESYRSCYVVENHLAIE 116
           ++ SY+R K  EHS      Y+     + ++   + YV+ R L+   S  V+E+H+ ++
Sbjct: 51  VLESYVREKHSEHSRSALESYVRDKHSEPRNIVLETYVRDRHLDPRSS--VLESHVRVK 107


>gi|193788732 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 5 [Homo sapiens]
          Length = 2166

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 44   ALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVY 81
            A+ +L +L F G FT+ ++L  I  K   + +DP+NV+
Sbjct: 1250 AMNILNML-FTGLFTVEMILKLIAFKPKGYFSDPWNVF 1286


>gi|193788724 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 2 [Homo sapiens]
          Length = 2186

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 44   ALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVY 81
            A+ +L +L F G FT+ ++L  I  K   + +DP+NV+
Sbjct: 1270 AMNILNML-FTGLFTVEMILKLIAFKPKGYFSDPWNVF 1306


>gi|193788720 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 1 [Homo sapiens]
          Length = 2221

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 44   ALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVY 81
            A+ +L +L F G FT+ ++L  I  K   + +DP+NV+
Sbjct: 1270 AMNILNML-FTGLFTVEMILKLIAFKPKGYFSDPWNVF 1306


>gi|193788544 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 19 [Homo sapiens]
          Length = 2135

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 44   ALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVY 81
            A+ +L +L F G FT+ ++L  I  K   + +DP+NV+
Sbjct: 1247 AMNILNML-FTGLFTVEMILKLIAFKPKGYFSDPWNVF 1283


>gi|193788540 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 16 [Homo sapiens]
          Length = 2138

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 44   ALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVY 81
            A+ +L +L F G FT+ ++L  I  K   + +DP+NV+
Sbjct: 1250 AMNILNML-FTGLFTVEMILKLIAFKPKGYFSDPWNVF 1286


>gi|193788538 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 15 [Homo sapiens]
          Length = 2138

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 44   ALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVY 81
            A+ +L +L F G FT+ ++L  I  K   + +DP+NV+
Sbjct: 1250 AMNILNML-FTGLFTVEMILKLIAFKPKGYFSDPWNVF 1286


>gi|193794830 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 10 [Homo sapiens]
          Length = 2155

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 44   ALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVY 81
            A+ +L +L F G FT+ ++L  I  K   + +DP+NV+
Sbjct: 1250 AMNILNML-FTGLFTVEMILKLIAFKPKGYFSDPWNVF 1286


>gi|193794828 calcium channel, voltage-dependent, L type, alpha 1C
            subunit isoform 7 [Homo sapiens]
          Length = 2157

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 14/38 (36%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 44   ALYVLMVLGFFGFFTLGIMLSYIRSKKLEHSNDPFNVY 81
            A+ +L +L F G FT+ ++L  I  K   + +DP+NV+
Sbjct: 1250 AMNILNML-FTGLFTVEMILKLIAFKPKGYFSDPWNVF 1286


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 26.2 bits (56), Expect = 7.6
 Identities = 16/58 (27%), Positives = 25/58 (43%)

Query: 67  RSKKLEHSNDPFNVYIESDAWQEKDKAYVQARVLESYRSCYVVENHLAIEQPNTHLPE 124
           R KK +    PF+   +S    E   + ++ +  E  RS    EN  +  Q N H+ E
Sbjct: 678 REKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHE 735


>gi|148225857 G protein-coupled receptor 34 [Homo sapiens]
          Length = 381

 Score = 25.8 bits (55), Expect = 9.9
 Identities = 15/51 (29%), Positives = 28/51 (54%)

Query: 20  TVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKK 70
           T+++GG+ S +        + K EA++  +++  F    L I+LSYI+  K
Sbjct: 193 TLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIKIGK 243


>gi|4885319 G protein-coupled receptor 34 [Homo sapiens]
          Length = 381

 Score = 25.8 bits (55), Expect = 9.9
 Identities = 15/51 (29%), Positives = 28/51 (54%)

Query: 20  TVQQGGNMSGLARRSPRSSDGKLEALYVLMVLGFFGFFTLGIMLSYIRSKK 70
           T+++GG+ S +        + K EA++  +++  F    L I+LSYI+  K
Sbjct: 193 TLKKGGHNSTMCFHYRDKHNAKGEAIFNFILVVMFWLIFLLIILSYIKIGK 243


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,845,710
Number of Sequences: 37866
Number of extensions: 175021
Number of successful extensions: 384
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 370
Number of HSP's gapped (non-prelim): 24
length of query: 129
length of database: 18,247,518
effective HSP length: 90
effective length of query: 39
effective length of database: 14,839,578
effective search space: 578743542
effective search space used: 578743542
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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