BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|189083782 gelsolin isoform c [Homo sapiens] (742 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|189083782 gelsolin isoform c [Homo sapiens] 1510 0.0 gi|189083780 gelsolin isoform c [Homo sapiens] 1510 0.0 gi|4504165 gelsolin isoform a precursor [Homo sapiens] 1491 0.0 gi|38044288 gelsolin isoform b [Homo sapiens] 1485 0.0 gi|189083778 gelsolin isoform b [Homo sapiens] 1485 0.0 gi|189083776 gelsolin isoform b [Homo sapiens] 1485 0.0 gi|189083774 gelsolin isoform b [Homo sapiens] 1485 0.0 gi|189083772 gelsolin isoform b [Homo sapiens] 1485 0.0 gi|162951877 scinderin isoform 1 [Homo sapiens] 915 0.0 gi|194394237 villin 1 [Homo sapiens] 684 0.0 gi|17572824 advillin [Homo sapiens] 642 0.0 gi|14916473 scinderin isoform 2 [Homo sapiens] 601 e-172 gi|94721268 villin-like protein [Homo sapiens] 503 e-142 gi|63252913 gelsolin-like capping protein [Homo sapiens] 342 6e-94 gi|4503743 flightless I homolog [Homo sapiens] 258 2e-68 gi|150417973 supervillin isoform 2 [Homo sapiens] 139 1e-32 gi|150417971 supervillin isoform 1 [Homo sapiens] 139 1e-32 gi|139394599 hypermethylated in cancer 2 [Homo sapiens] 31 3.6 gi|109637761 calpastatin isoform g [Homo sapiens] 31 4.8 gi|38569394 inhibitor of kappa light polypeptide gene enhancer i... 30 6.2 gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] 30 6.2 >gi|189083782 gelsolin isoform c [Homo sapiens] Length = 742 Score = 1510 bits (3910), Expect = 0.0 Identities = 742/742 (100%), Positives = 742/742 (100%) Query: 1 MEKLFCCFPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKT 60 MEKLFCCFPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKT Sbjct: 1 MEKLFCCFPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKT 60 Query: 61 VQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGY 120 VQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGY Sbjct: 61 VQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGY 120 Query: 121 FKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDL 180 FKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDL Sbjct: 121 FKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDL 180 Query: 181 GNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPAL 240 GNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPAL Sbjct: 181 GNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPAL 240 Query: 241 PAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 300 PAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG Sbjct: 241 PAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 300 Query: 301 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPD 360 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPD Sbjct: 301 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPD 360 Query: 361 QTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPV 420 QTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPV Sbjct: 361 QTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPV 420 Query: 421 DPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGT 480 DPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGT Sbjct: 421 DPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGT 480 Query: 481 PVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVE 540 PVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVE Sbjct: 481 PVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVE 540 Query: 541 VLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDG 600 VLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDG Sbjct: 541 VLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDG 600 Query: 601 FWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVML 660 FWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVML Sbjct: 601 FWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVML 660 Query: 661 LDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWF 720 LDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWF Sbjct: 661 LDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWF 720 Query: 721 LGWDDDYWSVDPLDRAMAELAA 742 LGWDDDYWSVDPLDRAMAELAA Sbjct: 721 LGWDDDYWSVDPLDRAMAELAA 742 >gi|189083780 gelsolin isoform c [Homo sapiens] Length = 742 Score = 1510 bits (3910), Expect = 0.0 Identities = 742/742 (100%), Positives = 742/742 (100%) Query: 1 MEKLFCCFPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKT 60 MEKLFCCFPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKT Sbjct: 1 MEKLFCCFPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKT 60 Query: 61 VQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGY 120 VQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGY Sbjct: 61 VQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGY 120 Query: 121 FKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDL 180 FKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDL Sbjct: 121 FKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDL 180 Query: 181 GNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPAL 240 GNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPAL Sbjct: 181 GNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPAL 240 Query: 241 PAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 300 PAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG Sbjct: 241 PAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDG 300 Query: 301 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPD 360 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPD Sbjct: 301 KIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPD 360 Query: 361 QTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPV 420 QTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPV Sbjct: 361 QTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPV 420 Query: 421 DPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGT 480 DPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGT Sbjct: 421 DPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGT 480 Query: 481 PVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVE 540 PVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVE Sbjct: 481 PVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVE 540 Query: 541 VLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDG 600 VLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDG Sbjct: 541 VLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDG 600 Query: 601 FWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVML 660 FWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVML Sbjct: 601 FWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVML 660 Query: 661 LDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWF 720 LDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWF Sbjct: 661 LDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWF 720 Query: 721 LGWDDDYWSVDPLDRAMAELAA 742 LGWDDDYWSVDPLDRAMAELAA Sbjct: 721 LGWDDDYWSVDPLDRAMAELAA 742 >gi|4504165 gelsolin isoform a precursor [Homo sapiens] Length = 782 Score = 1491 bits (3861), Expect = 0.0 Identities = 734/734 (100%), Positives = 734/734 (100%) Query: 9 PNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNL 68 PNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNL Sbjct: 49 PNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNL 108 Query: 69 QYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYK 128 QYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYK Sbjct: 109 QYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYK 168 Query: 129 KGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWC 188 KGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWC Sbjct: 169 KGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWC 228 Query: 189 GSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTA 248 GSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTA Sbjct: 229 GSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTA 288 Query: 249 KEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGK 308 KEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGK Sbjct: 289 KEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGK 348 Query: 309 QANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLS 368 QANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLS Sbjct: 349 QANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLS 408 Query: 369 YLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQF 428 YLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQF Sbjct: 409 YLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQF 468 Query: 429 YGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQ 488 YGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQ Sbjct: 469 YGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQ 528 Query: 489 GKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGAL 548 GKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGAL Sbjct: 529 GKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGAL 588 Query: 549 NSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGK 608 NSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGK Sbjct: 589 NSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGK 648 Query: 609 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF 668 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF Sbjct: 649 AAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVF 708 Query: 669 VWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 728 VWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW Sbjct: 709 VWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 768 Query: 729 SVDPLDRAMAELAA 742 SVDPLDRAMAELAA Sbjct: 769 SVDPLDRAMAELAA 782 >gi|38044288 gelsolin isoform b [Homo sapiens] Length = 731 Score = 1485 bits (3844), Expect = 0.0 Identities = 731/731 (100%), Positives = 731/731 (100%) Query: 12 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 71 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD Sbjct: 1 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 60 Query: 72 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 131 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG Sbjct: 61 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120 Query: 132 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 191 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN Sbjct: 121 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 180 Query: 192 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 251 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED Sbjct: 181 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 240 Query: 252 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 311 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN Sbjct: 241 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 300 Query: 312 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 371 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS Sbjct: 301 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 360 Query: 372 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 431 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG Sbjct: 361 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 420 Query: 432 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 491 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE Sbjct: 421 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 480 Query: 492 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 551 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN Sbjct: 481 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 540 Query: 552 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 611 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY Sbjct: 541 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 600 Query: 612 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 671 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660 Query: 672 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 731 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 720 Query: 732 PLDRAMAELAA 742 PLDRAMAELAA Sbjct: 721 PLDRAMAELAA 731 >gi|189083778 gelsolin isoform b [Homo sapiens] Length = 731 Score = 1485 bits (3844), Expect = 0.0 Identities = 731/731 (100%), Positives = 731/731 (100%) Query: 12 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 71 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD Sbjct: 1 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 60 Query: 72 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 131 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG Sbjct: 61 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120 Query: 132 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 191 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN Sbjct: 121 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 180 Query: 192 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 251 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED Sbjct: 181 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 240 Query: 252 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 311 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN Sbjct: 241 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 300 Query: 312 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 371 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS Sbjct: 301 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 360 Query: 372 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 431 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG Sbjct: 361 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 420 Query: 432 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 491 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE Sbjct: 421 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 480 Query: 492 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 551 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN Sbjct: 481 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 540 Query: 552 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 611 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY Sbjct: 541 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 600 Query: 612 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 671 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660 Query: 672 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 731 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 720 Query: 732 PLDRAMAELAA 742 PLDRAMAELAA Sbjct: 721 PLDRAMAELAA 731 >gi|189083776 gelsolin isoform b [Homo sapiens] Length = 731 Score = 1485 bits (3844), Expect = 0.0 Identities = 731/731 (100%), Positives = 731/731 (100%) Query: 12 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 71 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD Sbjct: 1 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 60 Query: 72 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 131 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG Sbjct: 61 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120 Query: 132 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 191 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN Sbjct: 121 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 180 Query: 192 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 251 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED Sbjct: 181 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 240 Query: 252 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 311 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN Sbjct: 241 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 300 Query: 312 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 371 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS Sbjct: 301 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 360 Query: 372 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 431 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG Sbjct: 361 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 420 Query: 432 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 491 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE Sbjct: 421 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 480 Query: 492 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 551 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN Sbjct: 481 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 540 Query: 552 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 611 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY Sbjct: 541 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 600 Query: 612 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 671 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660 Query: 672 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 731 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 720 Query: 732 PLDRAMAELAA 742 PLDRAMAELAA Sbjct: 721 PLDRAMAELAA 731 >gi|189083774 gelsolin isoform b [Homo sapiens] Length = 731 Score = 1485 bits (3844), Expect = 0.0 Identities = 731/731 (100%), Positives = 731/731 (100%) Query: 12 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 71 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD Sbjct: 1 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 60 Query: 72 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 131 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG Sbjct: 61 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120 Query: 132 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 191 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN Sbjct: 121 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 180 Query: 192 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 251 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED Sbjct: 181 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 240 Query: 252 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 311 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN Sbjct: 241 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 300 Query: 312 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 371 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS Sbjct: 301 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 360 Query: 372 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 431 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG Sbjct: 361 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 420 Query: 432 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 491 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE Sbjct: 421 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 480 Query: 492 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 551 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN Sbjct: 481 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 540 Query: 552 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 611 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY Sbjct: 541 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 600 Query: 612 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 671 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660 Query: 672 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 731 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 720 Query: 732 PLDRAMAELAA 742 PLDRAMAELAA Sbjct: 721 PLDRAMAELAA 731 >gi|189083772 gelsolin isoform b [Homo sapiens] Length = 731 Score = 1485 bits (3844), Expect = 0.0 Identities = 731/731 (100%), Positives = 731/731 (100%) Query: 12 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 71 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD Sbjct: 1 MVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 60 Query: 72 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 131 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG Sbjct: 61 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 120 Query: 132 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 191 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN Sbjct: 121 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 180 Query: 192 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 251 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED Sbjct: 181 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 240 Query: 252 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 311 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN Sbjct: 241 AANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQAN 300 Query: 312 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 371 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS Sbjct: 301 TEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLS 360 Query: 372 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 431 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG Sbjct: 361 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 420 Query: 432 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 491 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE Sbjct: 421 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 480 Query: 492 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 551 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN Sbjct: 481 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 540 Query: 552 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 611 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY Sbjct: 541 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAY 600 Query: 612 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 671 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV Sbjct: 601 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 660 Query: 672 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 731 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD Sbjct: 661 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVD 720 Query: 732 PLDRAMAELAA 742 PLDRAMAELAA Sbjct: 721 PLDRAMAELAA 731 >gi|162951877 scinderin isoform 1 [Homo sapiens] Length = 715 Score = 915 bits (2366), Expect = 0.0 Identities = 431/715 (60%), Positives = 547/715 (76%), Gaps = 8/715 (1%) Query: 16 HPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYW 75 H EF +AGK+ GLQ+WR+EK +LVPVP + +GDF+ GDAY++L T + G Y LH+W Sbjct: 7 HEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRG-FTYHLHFW 65 Query: 76 LGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASG 135 LG ECSQDES AAAIFTVQ+DDYL G+ VQ+RE+QG+ES F+ YFK GLKYK GGVASG Sbjct: 66 LGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASG 125 Query: 136 FKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRY 195 HV+ N++ +RL VKGRRVVRATEVP+SW+SFN GDCFI+DLG I+QWCGS+ N+Y Sbjct: 126 LNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKY 185 Query: 196 ERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALP-AGTEDTAKEDAAN 254 ERLKA QV+ GIR NER GR+ + V EEG+EP +++VLG KP LP G +D D +N Sbjct: 186 ERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISN 245 Query: 255 RKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEE 314 RK+AKLY VS+ +G+M V++VA+ENPF+ L SE+CFILDHG +IFVWKGK AN +E Sbjct: 246 RKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQE 305 Query: 315 RKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHI 374 RKAA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G Y++ + Sbjct: 306 RKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKV 365 Query: 375 ANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSY 434 A ++++PFDA+ LH+S MAAQH M DDG+G+ +IWR+E + ++ VD +YG+FYGGD Y Sbjct: 366 AQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCY 425 Query: 435 IILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAH 494 IILY Y +GQIIY WQGA +T+DE+ SA LT QLD LGG VQ RV QGKEP H Sbjct: 426 IILYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVH 481 Query: 495 LMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAF 554 L+SLF KP+IIYK GTS++GGQ TRLFQVR N A TR VEV A +LNSND F Sbjct: 482 LLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVF 541 Query: 555 VLKTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRT 613 VLK P ++ Y+WVG GAS+ E+ GA+ + VL+ + +++ EG EP+ FW +LGGK Y+T Sbjct: 542 VLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQT 601 Query: 614 SPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGK 673 SP L+ + D HPPRL+ CSNK GRFVIEE+PGE Q+DLA DDVMLLD W+Q+F+W+GK Sbjct: 602 SPLLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGK 660 Query: 674 DSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 728 D+ E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD W Sbjct: 661 DANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 715 >gi|194394237 villin 1 [Homo sapiens] Length = 827 Score = 684 bits (1765), Expect = 0.0 Identities = 361/711 (50%), Positives = 452/711 (63%), Gaps = 14/711 (1%) Query: 26 PGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDES 85 PGLQIWR+E +VPVP++ +G FF GD Y+IL + +L YD+HYW+G + S DE Sbjct: 17 PGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIIL-AIHKTASSLSYDIHYWIGQDSSLDEQ 75 Query: 86 GAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVV 145 GAAAI+T Q+DD+L GRAVQHREVQG ES F GYFK GL +KGGVASG KHV N Sbjct: 76 GAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYD 135 Query: 146 VQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSK 205 VQRL VKG+R V A EV +SW+SFN GD F+LDLG I QW G S R ERL+ ++K Sbjct: 136 VQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAK 195 Query: 206 GIRDNERSGRARVHVSEEGTE------PEAMLQVLGPKPALPAGTEDTAKEDAANRKLAK 259 IRD ER GR V V + E E M VLG + L A DT E A L K Sbjct: 196 EIRDQERGGRTYVGVVDGENELASPKLMEVMNHVLGKRRELKAAVPDTVVEPALKAAL-K 254 Query: 260 LYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAAL 319 LY VS+ G + V VA P Q L EDC+ILD G KI+VWKGK+AN +E+K A+ Sbjct: 255 LYHVSDSEGNLVVREVATR-PLTQDLLSHEDCYILDQG-GLKIYVWKGKKANEQEKKGAM 312 Query: 320 KTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVER 379 A +FI YP TQV V +G E+ +F+Q F+ W ++T GLG ++ +A VE+ Sbjct: 313 SHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKWTASNRTSGLGKTHTVGSVAKVEQ 372 Query: 380 VPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYN 439 V FDA ++H +AAQ M DDG+G+ Q+WRIE VPVD G FYGGD Y++LY Sbjct: 373 VKFDATSMHVKPQVAAQQKMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYT 432 Query: 440 YRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLF 499 Y G +Q ++Y WQG+Q++QDE+ ASA LD++ G PVQ RV GKEP HLMS+F Sbjct: 433 YLIGEKQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIF 492 Query: 500 GGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTP 559 G+ M++Y+GGTSR STRLFQV+ A T+A EV +A LNSND FVLKT Sbjct: 493 KGR-MVVYQGGTSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQ 551 Query: 560 SAAYLWVGTGASEAEKTGAQELL-RVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLK 618 S YLW G G S E+ A+ + + R + V EG EP FW ALGGKA Y + RL+ Sbjct: 552 SCCYLWCGKGCSGDEREMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQ 611 Query: 619 DKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEE 678 ++ + PRLF CSNK GRF+ E+P + Q+DL DDV LLD WDQVF W+GK + EE Sbjct: 612 EENL-VITPRLFECSNKTGRFLATEIP-DFNQDDLEEDDVFLLDVWDQVFFWIGKHANEE 669 Query: 679 EKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 729 EK A T+A+ Y++T P+ RD TPI VVKQG EPP+F GWFL WD WS Sbjct: 670 EKKAAATTAQEYLKTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWS 720 >gi|17572824 advillin [Homo sapiens] Length = 819 Score = 642 bits (1655), Expect = 0.0 Identities = 339/718 (47%), Positives = 442/718 (61%), Gaps = 14/718 (1%) Query: 19 FLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGN 78 F +PG+ +WR+EK +L VP + +G+F+ GD YVIL T ++ + L D+H+W+G Sbjct: 7 FRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVAS-LLSQDIHFWIGK 65 Query: 79 ECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKH 138 + SQDE AAI+T QLDDYL G VQHREVQ ES TF GYFK G+ YK+GGVASG KH Sbjct: 66 DSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKH 125 Query: 139 VVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERL 198 V N V+RL VKG+R +RATEV +SW+SFN GD F+LDLG I QW G SN ERL Sbjct: 126 VETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERL 185 Query: 199 KATQVSKGIRDNERSGRARVHVSE---EGTEPEAML---QVLGPKPALPAGTEDTAKEDA 252 KA ++K IRD ER GRA + V E E PE M LG + + D D Sbjct: 186 KAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEII-DQ 244 Query: 253 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 312 + LY +S+ AG ++V+ VA P Q L +DC+ILD KI+VWKGK A Sbjct: 245 KQKSTIMLYHISDSAGQLAVTEVATR-PLVQDLLNHDDCYILDQSGT-KIYVWKGKGATK 302 Query: 313 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSS 372 E++AA+ A FI YP T V + +G E+ +FKQ F+ W DQT GLG ++ Sbjct: 303 AEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIG 362 Query: 373 HIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGD 432 IA V + FD LHT +AAQ M DDG G+ ++WRIE VPV+ YG FYGGD Sbjct: 363 KIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGD 422 Query: 433 SYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 492 Y++LY Y G+ I+Y WQG ++QDE+AASA ++D + G VQ RV G EP Sbjct: 423 CYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEP 482 Query: 493 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 552 H M++F GK ++I++GGTSR+G RLFQ+ N T+AVEV A +LNSND Sbjct: 483 RHFMAIFKGK-LVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSND 541 Query: 553 AFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAAY 611 F+L+T + YLW G G+S E+ A+EL +L VAEG EP FW+ LGGK Y Sbjct: 542 VFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPY 601 Query: 612 RTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWV 671 RL+ + +D RLF CSNK G+FV+ E+ + Q+DL DVMLLDTWDQVF+W+ Sbjct: 602 ANDKRLQQEILDVQ-SRLFECSNKTGQFVVTEIT-DFTQDDLNPTDVMLLDTWDQVFLWI 659 Query: 672 GKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWS 729 G ++ EK AL +A++Y+ T P+ RD TPI ++KQGFEPP F GWFL WD + WS Sbjct: 660 GAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWS 717 >gi|14916473 scinderin isoform 2 [Homo sapiens] Length = 468 Score = 601 bits (1549), Expect = e-172 Identities = 281/473 (59%), Positives = 360/473 (76%), Gaps = 6/473 (1%) Query: 257 LAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERK 316 +AKLY VS+ +G+M V++VA+ENPF+ L SE+CFILDHG +IFVWKGK AN +ERK Sbjct: 1 MAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERK 60 Query: 317 AALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIAN 376 AA+KTA +F+ +M+Y K TQ+ VLPEGGETP+FKQFFK+WRD DQ+DG G Y++ +A Sbjct: 61 AAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQ 120 Query: 377 VERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYII 436 ++++PFDA+ LH+S MAAQH M DDG+G+ +IWR+E + ++ VD +YG+FYGGD YII Sbjct: 121 IKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYII 180 Query: 437 LYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLM 496 LY Y +GQIIY WQGA +T+DE+ SA LT QLD LGG VQ RV QGKEP HL+ Sbjct: 181 LYTY----PRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLL 236 Query: 497 SLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVL 556 SLF KP+IIYK GTS++GGQ TRLFQVR N A TR VEV A +LNSND FVL Sbjct: 237 SLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVL 296 Query: 557 KTP-SAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSP 615 K P ++ Y+WVG GAS+ E+ GA+ + VL+ + +++ EG EP+ FW +LGGK Y+TSP Sbjct: 297 KLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSP 356 Query: 616 RLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDS 675 L+ + D HPPRL+ CSNK GRFVIEE+PGE Q+DLA DDVMLLD W+Q+F+W+GKD+ Sbjct: 357 LLETQAED-HPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDA 415 Query: 676 QEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYW 728 E EK E+L SAK Y+ETDP+ RD+RTPI ++KQG EPP+F GWFLGWD W Sbjct: 416 NEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW 468 Score = 135 bits (340), Expect = 1e-31 Identities = 110/337 (32%), Positives = 155/337 (45%), Gaps = 32/337 (9%) Query: 28 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGA 87 ++IWRVE + V N YG+F+ GD Y+IL T G + Y W G ++DE Sbjct: 151 VEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYP--RGQIIYT---WQGANATRDELTT 205 Query: 88 AAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSG--LKYKKGGVASGFKHVVPNEVV 145 +A TVQLD L G+AVQ R QG E L FK + YK G G + P Sbjct: 206 SAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAP---- 261 Query: 146 VQRLFQVKGR--RVVRATEVPVSWESFNNGDCFILDLGNNI-HQWCGSNSNRYERLKATQ 202 RLFQV+ + R EV V S N+ D F+L L N + W G +++ E A Sbjct: 262 PTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEY 321 Query: 203 VSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAG-TEDTAKEDAANRKLAKLY 261 V+ + + + +EG EPE LG K +T ED R LY Sbjct: 322 VASVL-------KCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLETQAEDHPPR----LY 370 Query: 262 KVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKT 321 SN G + + E F Q L +D +LD + +IF+W GK AN E+K +LK+ Sbjct: 371 GCSNKTGRFVIEEIPGE--FTQDDLAEDDVMLLDAWE--QIFIWIGKDANEVEKKESLKS 426 Query: 322 ASDFI--TKMDYPKQTQVSVLPEGGETPLFKQFFKNW 356 A ++ K+T + ++ +G E P F +F W Sbjct: 427 AKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGW 463 Score = 37.0 bits (84), Expect = 0.066 Identities = 47/203 (23%), Positives = 79/203 (38%), Gaps = 37/203 (18%) Query: 155 RRVVRATEVPVSWESFNNGDCFILDLG--NNIHQWCGSNSNRYERLKATQVSKG-IRDNE 211 R V A E P S + +CFILD G I W G ++N ER A + ++ ++ Sbjct: 15 RVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMN 74 Query: 212 RSGRARVHVSEEGTEPEAMLQ------------------VLGPKPALPAGTEDTAKEDAA 253 S ++ V EG E Q V + D +K ++ Sbjct: 75 YSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIKQIPFDASKLHSS 134 Query: 254 NRKLAKLYKVSNGAGTMSV-------SLVADENPFAQGALKSEDCFIL--DHGKDGKIFV 304 + A+ V +G+G + + + D+N + G DC+I+ + + I+ Sbjct: 135 PQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSY--GEFYGGDCYIILYTYPRGQIIYT 192 Query: 305 WKGKQANTEERKAALKTASDFIT 327 W+G A +E T S F+T Sbjct: 193 WQGANATRDE-----LTTSAFLT 210 >gi|94721268 villin-like protein [Homo sapiens] Length = 856 Score = 503 bits (1295), Expect = e-142 Identities = 290/729 (39%), Positives = 414/729 (56%), Gaps = 28/729 (3%) Query: 23 GKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGN--LQYDLHYWLGNEC 80 G + GL IW E +VPVP YG+FF YVIL Q DLHYW+G + Sbjct: 9 GMQGGLHIWISENRKMVPVPEGAYGNFFEEHCYVILHVPQSPKATQGASSDLHYWVGKQA 68 Query: 81 SQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVV 140 + GAA F +L D L G+ V HRE QG ES F YF+ G+ Y+KGG+AS KHV Sbjct: 69 GAEAQGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGIIYRKGGLASDLKHVE 128 Query: 141 PNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKA 200 N +QRL +KGR+ V ATEV +SW SFN GD F+LDLG + QW G ++ E+ + Sbjct: 129 TNLFNIQRLLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARG 188 Query: 201 TQVSKGIRDNER-SGRARVHVSEEGTEPEAMLQ----VLGPK-PALPAGT--EDTAKEDA 252 ++ +RD ER GRA++ V ++ + ++Q VLG + +L A T +D + Sbjct: 189 LALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSLRAATPSKDINQLQK 248 Query: 253 ANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANT 312 AN +L +Y+ G V L P Q L+ ED +ILD G KI+VW+G+ ++ Sbjct: 249 ANVRLYHVYE----KGKDLVVLELATPPLTQDLLQEEDFYILDQG-GFKIYVWQGRMSSL 303 Query: 313 EERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDP-DQTDGLGLSYLS 371 +ERKAA A FI YP T V V+ +G E+ FKQ F+ W + + LG S Sbjct: 304 QERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSEKRRRNQKLGGRDKS 363 Query: 372 SHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGG 431 H V D LHT +AAQ M DDG+G+ ++W I+ ++ PVDP +GQ G Sbjct: 364 IH------VKLDVGKLHTQPKLAAQLRMVDDGSGKVEVWCIQDLHRQPVDPKRHGQLCAG 417 Query: 432 DSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKE 491 + Y++LY Y+ GR I+Y WQG Q+T DE+ A +LD GG VQ V G E Sbjct: 418 NCYLVLYTYQRLGRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSE 477 Query: 492 PAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSN 551 P H +++F G+ ++I++ G + ++TRLFQV+ + TR +EV +A +LNS+ Sbjct: 478 PPHFLAIFQGQ-LVIFQERAGHHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSS 536 Query: 552 DAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVL-RAQPVQVAEGSEPDGFWEALGGKAA 610 D F+L T S YLW G G + ++ A+ ++ V+ R V EG EP FWEALGG+A Sbjct: 537 DIFLLVTASVCYLWFGKGCNGDQREMARVVVTVISRKNEETVLEGQEPPHFWEALGGRAP 596 Query: 611 YRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVW 670 Y ++ RL + ++ + PRLF CS+ +G V+ EV G QEDL D+MLLDTW ++F+W Sbjct: 597 YPSNKRLPE-EVPSFQPRLFECSSHMGCLVLAEV-GFFSQEDLDKYDIMLLDTWQEIFLW 654 Query: 671 VGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSV 730 +G+ + E + EA+ + Y++T PA R TPI +VKQG EPP+F+GWF WD W+ Sbjct: 655 LGEAASEWK--EAVAWGQEYLKTHPAGRSPATPIVLVKQGHEPPTFIGWFFTWDPYKWTS 712 Query: 731 DPLDRAMAE 739 P + + + Sbjct: 713 HPSHKEVVD 721 >gi|63252913 gelsolin-like capping protein [Homo sapiens] Length = 348 Score = 342 bits (878), Expect = 6e-94 Identities = 171/337 (50%), Positives = 230/337 (68%), Gaps = 8/337 (2%) Query: 24 KEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD-LHYWLGNECSQ 82 ++PGL +WRVEK VPV G FF+GD+Y++L NG + LH W+G + S+ Sbjct: 17 QDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVL-----HNGPEEVSHLHLWIGQQSSR 71 Query: 83 DESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGF-KHVVP 141 DE GA A+ V L+ L R VQHREVQG ES F+ YF GLKY++GGV S F K Sbjct: 72 DEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG 131 Query: 142 NEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKAT 201 +++L+QVKG++ +RATE ++W+SFN GDCFILDLG NI WCG SN ER KA Sbjct: 132 APAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191 Query: 202 QVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGT-EDTAKEDAANRKLAKL 260 ++ IRD+ER G+A+V + +G EP M+QVLGPKPAL G E+ D AN + A L Sbjct: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251 Query: 261 YKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALK 320 YKVS+ G M+++ VAD +PFA L S+DCF+LD+G GKI++WKG++AN +ER+AAL+ Sbjct: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311 Query: 321 TASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWR 357 A FI++M Y TQV +LP+G E+P+FKQFFK+W+ Sbjct: 312 VAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK 348 Score = 125 bits (314), Expect = 1e-28 Identities = 100/338 (29%), Positives = 154/338 (45%), Gaps = 36/338 (10%) Query: 409 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAI 468 +WR+E VPV G F+ GDSY++L+N G + ++ W G QS++DE A A+ Sbjct: 23 VWRVEKLKPVPVAQENQGVFFSGDSYLVLHN---GPEEVSHLHLWIGQQSSRDEQGACAV 79 Query: 469 LTAQLDEELGGTPVQSRVVQGKEPAHLMSLF--------GGKPMIIYKGGTSREGGQTAP 520 L L+ LG PVQ R VQG E MS F GG +K T AP Sbjct: 80 LAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTG------AP 133 Query: 521 AS-TRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQ 579 A+ +L+QV+ RA E + N+ D F+L + W G ++ E+ A+ Sbjct: 134 AAIKKLYQVKGKK--NIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKAR 191 Query: 580 ELLRVLR-------AQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKD---KKMDAHPPRL 629 +L +R AQ V +G EP + LG K A + +D K +A L Sbjct: 192 DLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAAL 251 Query: 630 FACSNKIGRFVIEEV--PGELMQEDLATDDVMLLDT--WDQVFVWVGKDSQEEEKTEALT 685 + S+ G+ + +V E L +DD +LD ++++W G+ + E+E+ AL Sbjct: 252 YKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQ 311 Query: 686 SAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGW 723 A+ +I T + ++ QG E P F +F W Sbjct: 312 VAEGFISR--MQYAPNTQVEILPQGHESPIFKQFFKDW 347 >gi|4503743 flightless I homolog [Homo sapiens] Length = 1269 Score = 258 bits (658), Expect = 2e-68 Identities = 221/795 (27%), Positives = 352/795 (44%), Gaps = 103/795 (12%) Query: 14 VEHPEFLK--AGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYD 71 +++ EF G+ PGL IW++E F V V +G F+ D Y++LKT +G+L ++ Sbjct: 485 LDYSEFFTEDVGQLPGLTIWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWE 544 Query: 72 LHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGG 131 ++YW+G E + D+ +AI V L +YL RE G ES FL F + + Y +GG Sbjct: 545 IYYWIGGEATLDKKACSAIHAVNLRNYLGAECRTVREEMGDESEEFLQVFDNDISYIEGG 604 Query: 132 VASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSN 191 ASGF + V + V R+++V G++ ++ VP+ S + F+LD G +I+ W G+ Sbjct: 605 TASGF-YTVEDTHYVTRMYRVYGKKNIKLEPVPLKGTSLDPRFVFLLDRGLDIYVWRGAQ 663 Query: 192 SNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKED 251 + KA ++ I NER G+A + + +G E + LG + P+ + ED Sbjct: 664 ATLSSTTKARLFAEKINKNERKGKAEITLLVQGQELPEFWEALGGE---PSEIKKHVPED 720 Query: 252 AANRKLAKLYKVSNGAGTM-------SVSLVADENP---------FAQGALKSEDCFILD 295 + KLYKV G G + +S+ + P Q L + +ILD Sbjct: 721 FWPPQ-PKLYKVGLGLGYLELPQINYKLSVEHKQRPKVELMPRMRLLQSLLDTRCVYILD 779 Query: 296 HGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKN 355 D +F+W G+++ R AALK + + P+ VS EG E +FK FKN Sbjct: 780 CWSD--VFIWLGRKSPRLVRAAALKLGQELCGMLHRPRHATVSRSLEGTEAQVFKAKFKN 837 Query: 356 WRDPDQTD----------GLGLS-YLSSHIANVERVPFDAATLH------TSTAMAAQ-- 396 W D D GLS + +++ D L S A A Q Sbjct: 838 WDDVLTVDYTRNAEAVLQSPGLSGKVKRDAEKKDQMKADLTALFLPRQPPMSLAEAEQLM 897 Query: 397 HGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNY---------------- 440 ++D G + + +EG + +G FY D Y+ L Y Sbjct: 898 EEWNEDLDGMEG-FVLEGKKFARLPEEEFGHFYTQDCYVFLCRYWVPVEYEEEEKKEDKE 956 Query: 441 -RHGGRQGQ-----------------IIYNWQGAQ-STQDEVAASAILTAQLDEELGGTP 481 + G++G+ I+Y WQG + S + + L + + G Sbjct: 957 EKAEGKEGEEATAEAEEKQPEEDFQCIVYFWQGREASNMGWLTFTFSLQKKFESLFPGKL 1016 Query: 482 VQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRAN-SAGATRAVE 540 R+ Q +E +S F K II++G G P+ L+Q+R N SA TR ++ Sbjct: 1017 EVVRMTQQQENPKFLSHFKRK-FIIHRGKRKAVQGAQQPS---LYQIRTNGSALCTRCIQ 1072 Query: 541 VLPKAGALNSNDAFVLKTP-------SAAYLWVGTGASEAEKTGAQELLRVL---RAQPV 590 + + LNS F+LK P Y WVG + E A+++L + Sbjct: 1073 INTDSSLLNSEFCFILKVPFESEDNQGIVYAWVGRASDPDEAKLAEDILNTMFDTSYSKQ 1132 Query: 591 QVAEGSEPDG-FWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELM 649 + EG EP+ FW +G + Y D + H RLF CSN+ G F + E + Sbjct: 1133 VINEGEEPENFFWVGIGAQKPYD-----DDAEYMKH-TRLFRCSNEKGYFAVTEKCSDFC 1186 Query: 650 QEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIE-TDPANRDRRTPITVVK 708 Q+DLA DD+MLLD +V++WVG + + E +L + + YI+ +R + +V+ Sbjct: 1187 QDDLADDDIMLLDNGQEVYMWVGTQTSQVEIKLSLKACQVYIQHMRSKEHERPRRLRLVR 1246 Query: 709 QGFEPPSFVGWFLGW 723 +G E +F F W Sbjct: 1247 KGNEQHAFTRCFHAW 1261 Score = 92.8 bits (229), Expect = 1e-18 Identities = 95/348 (27%), Positives = 141/348 (40%), Gaps = 41/348 (11%) Query: 409 IWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRH-GGRQGQIIYNWQGAQSTQDEVAASA 467 IW+IE V V+ A +G+FY D YI+L + G IY W G ++T D+ A SA Sbjct: 503 IWQIENFVPVLVEEAFHGKFYEADCYIVLKTFLDDSGSLNWEIYYWIGGEATLDKKACSA 562 Query: 468 ILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPAS---TR 524 I L LG R G E + +F I Y G + G T + TR Sbjct: 563 IHAVNLRNYLGAECRTVREEMGDESEEFLQVFDND--ISYIEGGTASGFYTVEDTHYVTR 620 Query: 525 LFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRV 584 +++V V + K +L+ F+L Y+W G A+ + T A+ Sbjct: 621 MYRVYGKKNIKLEPVPL--KGTSLDPRFVFLLDRGLDIYVWRGAQATLSSTTKARLFAEK 678 Query: 585 L-------RAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMDAHPP--RLFACSNK 635 + +A+ + +G E FWEALGG+ S K D PP +L+ Sbjct: 679 INKNERKGKAEITLLVQGQELPEFWEALGGEP----SEIKKHVPEDFWPPQPKLYKVGLG 734 Query: 636 IG-----------------RFVIEEVPG-ELMQEDLATDDVMLLDTWDQVFVWVGKDSQE 677 +G R +E +P L+Q L T V +LD W VF+W+G+ S Sbjct: 735 LGYLELPQINYKLSVEHKQRPKVELMPRMRLLQSLLDTRCVYILDCWSDVFIWLGRKSPR 794 Query: 678 EEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 725 + AL + +R R ++ +G E F F WDD Sbjct: 795 LVRAAALKLGQEL--CGMLHRPRHATVSRSLEGTEAQVFKAKFKNWDD 840 >gi|150417973 supervillin isoform 2 [Homo sapiens] Length = 2214 Score = 139 bits (349), Expect = 1e-32 Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%) Query: 149 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 208 L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+ Sbjct: 1445 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1504 Query: 209 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 259 G ++ EEG ++LG + + + + E +AA + Sbjct: 1505 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1564 Query: 260 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 315 +Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R Sbjct: 1565 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1616 Query: 316 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 350 K A + A I +D P++ Q L E ET LFK Sbjct: 1617 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1676 Query: 351 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 397 + F +W + +++ L+ H + + +P A T+ + + Sbjct: 1677 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1736 Query: 398 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 440 G+ + G ++Q +W I + + + GQF+ GD+Y++ + + Sbjct: 1737 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1795 Query: 441 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 492 R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP Sbjct: 1796 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1852 Query: 493 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 552 + F G M+++ G E + + RL+ VR +EV +L S Sbjct: 1853 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1910 Query: 553 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 596 + V+ + A YLW G A + ++ G ++ P++ EGS Sbjct: 1911 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1970 Query: 597 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 643 EP GFW+ALG + L+D PRLF S+ G F V+ Sbjct: 1971 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 2030 Query: 644 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 693 +P +QEDL + + L+D +V++W G E + T + + K +ET Sbjct: 2031 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 2088 Query: 694 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 724 N + P + ++ G EP +F F W+ Sbjct: 2089 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 2123 Score = 67.4 bits (163), Expect = 5e-11 Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%) Query: 28 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 73 + +W + +FD +P G F GDAYV+ V G+ Q H Sbjct: 1754 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1813 Query: 74 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 132 +W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V Sbjct: 1814 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1865 Query: 133 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 187 SG + V + RL+ V+G V EV S + ++ N I+ W Sbjct: 1866 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1925 Query: 188 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 240 G + + + + I++ S + +H +EG+EP LG + Sbjct: 1926 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1982 Query: 241 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 290 D +D + A +L+ +S+ +G + + V PF Q L S Sbjct: 1983 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 2042 Query: 291 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 335 F++D+ + +++W+G + +RK+A++T + + K Sbjct: 2043 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 2100 Query: 336 QVSVLPEGGETPL-FKQFFKNW 356 S L G PL F F +W Sbjct: 2101 PKSYLIHAGLEPLTFTNMFPSW 2122 >gi|150417971 supervillin isoform 1 [Homo sapiens] Length = 1788 Score = 139 bits (349), Expect = 1e-32 Identities = 164/695 (23%), Positives = 285/695 (41%), Gaps = 135/695 (19%) Query: 149 LFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIR 208 L Q+KGRR V+ V + N+GDCF+L + W G +N E+ KA++++ I+ Sbjct: 1019 LLQIKGRRHVQTRLVEPRASALNSGDCFLLLSPHCCFLWVGEFANVIEKAKASELATLIQ 1078 Query: 209 DNERSGRARVHVS--EEGTEPEA-----MLQVLGPKPALPAGTEDTAKE--DAANRKLAK 259 G ++ EEG ++LG + + + + E +AA + Sbjct: 1079 TKRELGCRATYIQTIEEGINTHTHAAKDFWKLLGGQTSYQSAGDPKEDELYEAAIIETNC 1138 Query: 260 LYKVSNGAGTMSVSLVADENPFAQ----GALKSEDCFILDHGKDGKIFVWKGKQANTEER 315 +Y++ M LV D++ + + L+ ++ + D G + ++VW GK+ +R Sbjct: 1139 IYRL------MDDKLVPDDDYWGKIPKCSLLQPKEVLVFDFGSE--VYVWHGKEVTLAQR 1190 Query: 316 KAALKTASDF-----------ITKMD-------YPKQTQ-------VSVLPEGGETPLFK 350 K A + A I +D P++ Q L E ET LFK Sbjct: 1191 KIAFQLAKHLWNGTFDYENCDINPLDPGECNPLIPRKGQGRPDWAIFGRLTEHNETILFK 1250 Query: 351 QFFKNWRDPDQTDGLGLSYLSSH------------IANVERVP-FDAATLHTSTAMAAQH 397 + F +W + +++ L+ H + + +P A T+ + + Sbjct: 1251 EKFLDWTELKRSNEKNPGELAQHKEDPRTDVKAYDVTRMVSMPQTTAGTILDGVNVGRGY 1310 Query: 398 GMDDDGTGQKQ---------IWRIEGSNKVPVDPATYGQFYGGDSYIILYNY-------- 440 G+ + G ++Q +W I + + + GQF+ GD+Y++ + + Sbjct: 1311 GLVE-GHDRRQFEITSVSVDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGS 1369 Query: 441 --------RHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEP 492 R G++ + + WQG ST E SA++T +LDEE G Q +V+QGKEP Sbjct: 1370 RQKGEHSVRAAGKEKCVYFFWQGRHSTVSEKGTSALMTVELDEERG---AQVQVLQGKEP 1426 Query: 493 AHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSND 552 + F G M+++ G E + + RL+ VR +EV +L S Sbjct: 1427 PCFLQCFQG-GMVVHSGRREEE-EENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRT 1484 Query: 553 AFVLKTPSAA--YLWVGTGA-SEAEKTGAQELLRVLRAQPVQVA-------------EGS 596 + V+ + A YLW G A + ++ G ++ P++ EGS Sbjct: 1485 SMVVLNVNKALIYLWHGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGS 1544 Query: 597 EPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF-------------VIEE 643 EP GFW+ALG + L+D PRLF S+ G F V+ Sbjct: 1545 EPLGFWDALGRRDRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSS 1604 Query: 644 VPGELMQEDLAT---DDVMLLDTWDQVFVWVGKDSQEEEKTEA-----LTSAKRYIET-- 693 +P +QEDL + + L+D +V++W G E + T + + K +ET Sbjct: 1605 MP--FLQEDLYSAPQPALFLVDNHHEVYLWQGWWPIENKITGSARIRWASDRKSAMETVL 1662 Query: 694 ---DPANRDRRTPIT-VVKQGFEPPSFVGWFLGWD 724 N + P + ++ G EP +F F W+ Sbjct: 1663 QYCKGKNLKKPAPKSYLIHAGLEPLTFTNMFPSWE 1697 Score = 67.4 bits (163), Expect = 5e-11 Identities = 87/382 (22%), Positives = 148/382 (38%), Gaps = 66/382 (17%) Query: 28 LQIWRVEKFDLVPVPTNLYGDFFTGDAYVI--LKTVQLRNGNLQYDLH------------ 73 + +W + +FD +P G F GDAYV+ V G+ Q H Sbjct: 1328 VDVWHILEFDYSRLPKQSIGQFHEGDAYVVKWKFMVSTAVGSRQKGEHSVRAAGKEKCVY 1387 Query: 74 -YWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGV 132 +W G + E G +A+ TV+LD+ R Q + +QG E FL F+ G+ V Sbjct: 1388 FFWQGRHSTVSEKGTSALMTVELDE---ERGAQVQVLQGKEPPCFLQCFQGGMV-----V 1439 Query: 133 ASGFKHVVPNEVVVQ-RLFQVKGRRVVRAT--EVPVSWESFNNGDCFILDLGNN--IHQW 187 SG + V + RL+ V+G V EV S + ++ N I+ W Sbjct: 1440 HSGRREEEEENVQSEWRLYCVRGEVPVEGNLLEVACHCSSLRSRTSMVVLNVNKALIYLW 1499 Query: 188 CGSNSNRYERLKATQVSKGIRDN-------ERSGRARVHVSEEGTEPEAMLQVLGPKPAL 240 G + + + + I++ S + +H +EG+EP LG + Sbjct: 1500 HGCKAQAHTKEVGRTAANKIKEQCPLEAGLHSSSKVTIHECDEGSEPLGFWDALGRR--- 1556 Query: 241 PAGTEDTAKEDAANRKLA-KLYKVSNGAGTMSVS---------LVADENPFAQGALKSED 290 D +D + A +L+ +S+ +G + + V PF Q L S Sbjct: 1557 DRKAYDCMLQDPGSFNFAPRLFILSSSSGDFAATEFVYPARAPSVVSSMPFLQEDLYSAP 1616 Query: 291 ---CFILDHGKDGKIFVWKG------------KQANTEERKAALKTASDFITKMDYPKQT 335 F++D+ + +++W+G + +RK+A++T + + K Sbjct: 1617 QPALFLVDNHHE--VYLWQGWWPIENKITGSARIRWASDRKSAMETVLQYCKGKNLKKPA 1674 Query: 336 QVSVLPEGGETPL-FKQFFKNW 356 S L G PL F F +W Sbjct: 1675 PKSYLIHAGLEPLTFTNMFPSW 1696 >gi|139394599 hypermethylated in cancer 2 [Homo sapiens] Length = 615 Score = 31.2 bits (69), Expect = 3.6 Identities = 30/114 (26%), Positives = 46/114 (40%), Gaps = 18/114 (15%) Query: 419 PVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELG 478 P+ PAT G D L + +HG + +A + + ELG Sbjct: 255 PLPPATPGPHLTPDDAAQLSDSQHG---------------SPPAASAPPVANSASYSELG 299 Query: 479 GTPVQSRVVQGKEPAHLMSLF--GGKPMIIYKGGT-SREGGQTAPASTRLFQVR 529 GTP + ++G E HL L GG+P + T +E G+ P + F+ R Sbjct: 300 GTPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERR 353 >gi|109637761 calpastatin isoform g [Homo sapiens] Length = 772 Score = 30.8 bits (68), Expect = 4.8 Identities = 36/146 (24%), Positives = 53/146 (36%), Gaps = 18/146 (12%) Query: 190 SNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAK 249 S+S KA VS+ + + + TEPE Q PK +LP DT Sbjct: 81 SSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKPK-SLPKQASDTGS 139 Query: 250 EDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGA---LKSEDCFILDHGKDGKIFVWK 306 DA N+K +VS A++ P + K +D I Sbjct: 140 NDAHNKK--------------AVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAIS 185 Query: 307 GKQANTEERKAALKTASDFITKMDYP 332 GK + ++ K +L A +K D P Sbjct: 186 GKPGDKKKEKKSLTPAVPVESKPDKP 211 >gi|38569394 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein [Homo sapiens] Length = 1332 Score = 30.4 bits (67), Expect = 6.2 Identities = 15/48 (31%), Positives = 25/48 (52%) Query: 678 EEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDD 725 E+ T + S IE DP +R+ + +++V +GF P G +G D Sbjct: 29 EQGTVLIGSEHGLIEVDPVSREVKNEVSLVAEGFLPEDGSGRIVGVQD 76 >gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] Length = 3639 Score = 30.4 bits (67), Expect = 6.2 Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 12/73 (16%) Query: 582 LRVLRAQPVQVAEGSEP--DGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRF 639 LR+ + A SE + +W ALG AA SP+LK K + + L C+ K R Sbjct: 3576 LRLTSGAEILFAAPSEEQAESWWRALGSTAAQSLSPKLKAKPVSS----LNECTTKDAR- 3630 Query: 640 VIEEVPGELMQED 652 PG L++ D Sbjct: 3631 -----PGCLLRSD 3638 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.134 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,523,205 Number of Sequences: 37866 Number of extensions: 1358656 Number of successful extensions: 3227 Number of sequences better than 10.0: 21 Number of HSP's better than 10.0 without gapping: 18 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 2889 Number of HSP's gapped (non-prelim): 43 length of query: 742 length of database: 18,247,518 effective HSP length: 110 effective length of query: 632 effective length of database: 14,082,258 effective search space: 8899987056 effective search space used: 8899987056 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.