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Search of human proteins with 100913030
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|100913030 solute carrier family 26 member 2 [Homo sapiens]
(739 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|100913030 solute carrier family 26 member 2 [Homo sapiens] 1457 0.0
gi|47131207 solute carrier family 26, member 1 isoform a [Homo s... 642 0.0
gi|20336272 solute carrier family 26, member 1 isoform a [Homo s... 642 0.0
gi|39752683 prestin isoform a [Homo sapiens] 461 e-130
gi|45827800 prestin isoform b [Homo sapiens] 452 e-127
gi|4505697 pendrin [Homo sapiens] 444 e-124
gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo s... 419 e-117
gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo s... 412 e-115
gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo s... 404 e-112
gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo s... 404 e-112
gi|4557535 solute carrier family 26, member 3 [Homo sapiens] 399 e-111
gi|45827802 prestin isoform c [Homo sapiens] 378 e-104
gi|16418413 solute carrier family 26, member 9 isoform a [Homo s... 358 1e-98
gi|217272867 solute carrier family 26, member 9 isoform b [Homo ... 358 1e-98
gi|16306483 solute carrier family 26, member 7 isoform a [Homo s... 342 1e-93
gi|20336282 solute carrier family 26, member 7 isoform b [Homo s... 340 3e-93
gi|16418457 solute carrier family 26, member 8 isoform a [Homo s... 253 3e-67
gi|65506789 solute carrier family 26, member 10 [Homo sapiens] 247 2e-65
gi|45827804 prestin isoform d [Homo sapiens] 222 1e-57
gi|85540447 solute carrier family 26, member 11 [Homo sapiens] 182 1e-45
gi|20336274 solute carrier family 26, member 1 isoform b [Homo s... 179 8e-45
gi|217272870 solute carrier family 26, member 9 isoform c [Homo ... 169 1e-41
gi|20336285 solute carrier family 26, member 8 isoform b [Homo s... 158 2e-38
gi|52317249 olfactory receptor, family 4, subfamily K, member 14... 34 0.43
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 33 1.2
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 33 1.2
gi|57165415 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glu... 33 1.2
gi|56121818 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glu... 33 1.2
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 32 2.1
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 31 4.7
>gi|100913030 solute carrier family 26 member 2 [Homo sapiens]
Length = 739
Score = 1457 bits (3773), Expect = 0.0
Identities = 739/739 (100%), Positives = 739/739 (100%)
Query: 1 MSSESKEQHNVSPRDSAEGNDSYPSGIHLELQRESSTDFKQFETNDQCRPYHRILIERQE 60
MSSESKEQHNVSPRDSAEGNDSYPSGIHLELQRESSTDFKQFETNDQCRPYHRILIERQE
Sbjct: 1 MSSESKEQHNVSPRDSAEGNDSYPSGIHLELQRESSTDFKQFETNDQCRPYHRILIERQE 60
Query: 61 KSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGI 120
KSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGI
Sbjct: 61 KSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGI 120
Query: 121 LLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDREL 180
LLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDREL
Sbjct: 121 LLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDREL 180
Query: 181 QKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQ 240
QKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQ
Sbjct: 181 QKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQ 240
Query: 241 VGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKT 300
VGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKT
Sbjct: 241 VGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKT 300
Query: 301 NLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSI 360
NLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSI
Sbjct: 301 NLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSI 360
Query: 361 AGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYA 420
AGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYA
Sbjct: 361 AGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYA 420
Query: 421 IGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQK 480
IGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQK
Sbjct: 421 IGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQK 480
Query: 481 SVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIF 540
SVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIF
Sbjct: 481 SVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIF 540
Query: 541 CVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALY 600
CVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALY
Sbjct: 541 CVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALY 600
Query: 601 KQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEMSVQLSHDPLELHTIVIDCSAIQFLD 660
KQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEMSVQLSHDPLELHTIVIDCSAIQFLD
Sbjct: 601 KQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEMSVQLSHDPLELHTIVIDCSAIQFLD 660
Query: 661 TAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCKKEEENLLFYSVYEAMAFAE 720
TAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCKKEEENLLFYSVYEAMAFAE
Sbjct: 661 TAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCKKEEENLLFYSVYEAMAFAE 720
Query: 721 VSKNQKGVCVPNGLSLSSD 739
VSKNQKGVCVPNGLSLSSD
Sbjct: 721 VSKNQKGVCVPNGLSLSSD 739
>gi|47131207 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 642 bits (1655), Expect = 0.0
Identities = 321/673 (47%), Positives = 462/673 (68%), Gaps = 11/673 (1%)
Query: 56 IERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSG 115
+ RQ + +E + +L +C CS + ++ LP +WL +Y ++ + GDVMSG
Sbjct: 17 VRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSG 76
Query: 116 LIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGET 175
L++GI+LVPQ+IAYSLLAG +P+Y LYTSFFA++IYFL+GTSRH+SVGIF +LCLM+G+
Sbjct: 77 LVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQV 136
Query: 176 VDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVA 235
VDRELQ AG+D + G +N STL + C + CYAI V + +T + G+YQV
Sbjct: 137 VDRELQLAGFDPSQDGLQPG--ANSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVL 194
Query: 236 MGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFR 295
MG ++GFVS YLS LL GF GAS TILTSQ K+LLG+ +PR G G ++ TW+ + R
Sbjct: 195 MGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLR 254
Query: 296 NIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHEN 355
+ N+CD++TS +CL VLL KEL++ ++ +L+ P+P EL+V+V ATL SHFG+LH+
Sbjct: 255 GAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKR 314
Query: 356 YNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKAN 415
+ SS+AG IPTGFMPP+VPE L+ VA+DA+A++++ A ++SL+EMFA+ HGY+V+AN
Sbjct: 315 FGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRAN 374
Query: 416 QEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLF 475
QE+ A+G CN++P+F HCF TSAALAK+LVK +TGC TQLS VV+A V+LLVLL +APLF
Sbjct: 375 QELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLF 434
Query: 476 YSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGV 535
+ LQ+SVL + +V+LRGALRK DLP++W +S D ++W T + L+STE GLL GV
Sbjct: 435 HDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGV 494
Query: 536 CFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECF 595
S+ + RTQ+P+++LL + ++ +E + ++ L +PG+++FRF PLYY NK+ F
Sbjct: 495 ILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFF 554
Query: 596 KSALYKQTVNPILIKVAWKK--AAKRKIKEKVVTLGGIQDEMSVQLSHDPLE--LHTIVI 651
+LY T A +K ++ + E G +S + + P HT+VI
Sbjct: 555 LQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRAALVPAAAGFHTVVI 614
Query: 652 DCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCKK-----EEEN 706
DC+ + FLD AG+ TL+++RRDY A+GI +LLA C+P VRD L+ G + + EE
Sbjct: 615 DCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEE 674
Query: 707 LLFYSVYEAMAFA 719
LF SV++A+ A
Sbjct: 675 QLFLSVHDAVQTA 687
>gi|20336272 solute carrier family 26, member 1 isoform a [Homo
sapiens]
Length = 701
Score = 642 bits (1655), Expect = 0.0
Identities = 321/673 (47%), Positives = 462/673 (68%), Gaps = 11/673 (1%)
Query: 56 IERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSG 115
+ RQ + +E + +L +C CS + ++ LP +WL +Y ++ + GDVMSG
Sbjct: 17 VRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSG 76
Query: 116 LIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGET 175
L++GI+LVPQ+IAYSLLAG +P+Y LYTSFFA++IYFL+GTSRH+SVGIF +LCLM+G+
Sbjct: 77 LVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQV 136
Query: 176 VDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVA 235
VDRELQ AG+D + G +N STL + C + CYAI V + +T + G+YQV
Sbjct: 137 VDRELQLAGFDPSQDGLQPG--ANSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVL 194
Query: 236 MGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFR 295
MG ++GFVS YLS LL GF GAS TILTSQ K+LLG+ +PR G G ++ TW+ + R
Sbjct: 195 MGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLR 254
Query: 296 NIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHEN 355
+ N+CD++TS +CL VLL KEL++ ++ +L+ P+P EL+V+V ATL SHFG+LH+
Sbjct: 255 GAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKR 314
Query: 356 YNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKAN 415
+ SS+AG IPTGFMPP+VPE L+ VA+DA+A++++ A ++SL+EMFA+ HGY+V+AN
Sbjct: 315 FGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRAN 374
Query: 416 QEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLF 475
QE+ A+G CN++P+F HCF TSAALAK+LVK +TGC TQLS VV+A V+LLVLL +APLF
Sbjct: 375 QELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLF 434
Query: 476 YSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGV 535
+ LQ+SVL + +V+LRGALRK DLP++W +S D ++W T + L+STE GLL GV
Sbjct: 435 HDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGV 494
Query: 536 CFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECF 595
S+ + RTQ+P+++LL + ++ +E + ++ L +PG+++FRF PLYY NK+ F
Sbjct: 495 ILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFF 554
Query: 596 KSALYKQTVNPILIKVAWKK--AAKRKIKEKVVTLGGIQDEMSVQLSHDPLE--LHTIVI 651
+LY T A +K ++ + E G +S + + P HT+VI
Sbjct: 555 LQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRAALVPAAAGFHTVVI 614
Query: 652 DCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCKK-----EEEN 706
DC+ + FLD AG+ TL+++RRDY A+GI +LLA C+P VRD L+ G + + EE
Sbjct: 615 DCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEE 674
Query: 707 LLFYSVYEAMAFA 719
LF SV++A+ A
Sbjct: 675 QLFLSVHDAVQTA 687
>gi|39752683 prestin isoform a [Homo sapiens]
Length = 744
Score = 461 bits (1187), Expect = e-130
Identities = 257/702 (36%), Positives = 401/702 (57%), Gaps = 53/702 (7%)
Query: 52 HRILIERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGD 111
H +L ER D + + KL++ C+P K +N+I FLP+ +WLP Y K+ +LGD
Sbjct: 25 HPVLQERLHTKD-KVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGD 83
Query: 112 VMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLM 171
++SG+ G+L +PQ +A+++LA P++GLY+SF+ I+Y LGTSRHIS+G F V+ LM
Sbjct: 84 LVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLM 143
Query: 172 IGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGV 231
IG R + P ++ G N T R + V +VT ++G+
Sbjct: 144 IGGVAVRLV-----------PDDIVIPGGVNATNGTEAR----DALRVKVAMSVTLLSGI 188
Query: 232 YQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWI 291
Q +G + GFV++YL++ L+ GF T A+ + TS KYL G+ R +G+ S++ + +
Sbjct: 189 IQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTV 248
Query: 292 HVFRNIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGK 351
V +N+ N+C L L+ +LL KE NE FK KL APIP+E VV T S
Sbjct: 249 AVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFN 308
Query: 352 LHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYT 411
L E+YN + G +P G +PP P+ +L V VDAIAI+I+GF++T+S+++ A KHGY
Sbjct: 309 LKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQ 368
Query: 412 VKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVI 471
V NQE+ A+G CN I S F F+ S +L+++LV+E TG TQL+G + +L++LLV+L
Sbjct: 369 VDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILAT 428
Query: 472 APLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGL 531
LF SL ++VL I IVNL+G +F DLP W S+++ IW T +SS L + GL
Sbjct: 429 GFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGL 488
Query: 532 LVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYIN 591
+ V ++ VI RTQ P +LG + E++V+ + AY+ ++ PGIKIF+ AP+YY N
Sbjct: 489 ITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYAN 548
Query: 592 KECFKSALYKQT-VNPILIKVAWKKAAKRKIKE---------KVVTLGGIQD-------- 633
+ + +AL ++T VNP +I A +KA ++ KE VV D
Sbjct: 549 SDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDATKPE 608
Query: 634 EMSVQLSHDPL------------------ELHTIVIDCSAIQFLDTAGIHTLKEVRRDYE 675
E ++ + P+ +HT+++D + + F+D+ G+ TL + ++Y
Sbjct: 609 EEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYG 668
Query: 676 AIGIQVLLAQCNPTVRDSLTNGEYCKKEE-ENLLFYSVYEAM 716
+GI V LA C+ V + LT + + LLF+S+++A+
Sbjct: 669 DVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAV 710
>gi|45827800 prestin isoform b [Homo sapiens]
Length = 685
Score = 452 bits (1162), Expect = e-127
Identities = 249/676 (36%), Positives = 387/676 (57%), Gaps = 52/676 (7%)
Query: 52 HRILIERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGD 111
H +L ER D + + KL++ C+P K +N+I FLP+ +WLP Y K+ +LGD
Sbjct: 25 HPVLQERLHTKD-KVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGD 83
Query: 112 VMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLM 171
++SG+ G+L +PQ +A+++LA P++GLY+SF+ I+Y LGTSRHIS+G F V+ LM
Sbjct: 84 LVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLM 143
Query: 172 IGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGV 231
IG R + P ++ G N T R + V +VT ++G+
Sbjct: 144 IGGVAVRLV-----------PDDIVIPGGVNATNGTEAR----DALRVKVAMSVTLLSGI 188
Query: 232 YQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWI 291
Q +G + GFV++YL++ L+ GF T A+ + TS KYL G+ R +G+ S++ + +
Sbjct: 189 IQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTV 248
Query: 292 HVFRNIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGK 351
V +N+ N+C L L+ +LL KE NE FK KL APIP+E VV T S
Sbjct: 249 AVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFN 308
Query: 352 LHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYT 411
L E+YN + G +P G +PP P+ +L V VDAIAI+I+GF++T+S+++ A KHGY
Sbjct: 309 LKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQ 368
Query: 412 VKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVI 471
V NQE+ A+G CN I S F F+ S +L+++LV+E TG TQL+G + +L++LLV+L
Sbjct: 369 VDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILAT 428
Query: 472 APLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGL 531
LF SL ++VL I IVNL+G +F DLP W S+++ IW T +SS L + GL
Sbjct: 429 GFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGL 488
Query: 532 LVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYIN 591
+ V ++ VI RTQ P +LG + E++V+ + AY+ ++ PGIKIF+ AP+YY N
Sbjct: 489 ITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYAN 548
Query: 592 KECFKSALYKQT-VNPILIKVAWKKAAKRKIKE---------KVVTLGGIQD-------- 633
+ + +AL ++T VNP +I A +KA ++ KE VV D
Sbjct: 549 SDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDATKPE 608
Query: 634 EMSVQLSHDPL------------------ELHTIVIDCSAIQFLDTAGIHTLKEVRRDYE 675
E ++ + P+ +HT+++D + + F+D+ G+ TL + ++Y
Sbjct: 609 EEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYG 668
Query: 676 AIGIQVLLAQCNPTVR 691
+GI V LA C+ ++
Sbjct: 669 DVGIYVYLAGCSAFIQ 684
>gi|4505697 pendrin [Homo sapiens]
Length = 780
Score = 444 bits (1142), Expect = e-124
Identities = 246/725 (33%), Positives = 407/725 (56%), Gaps = 61/725 (8%)
Query: 51 YHRILIERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILG 110
Y + ++Q + ++ + + L K C CS +A ++ +P+L+WLPKY +K+ +L
Sbjct: 27 YSELAFQQQHERRLQERKTLRESLAKCCSCSRKRAFGVLKTLVPILEWLPKYRVKEWLLS 86
Query: 111 DVMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCL 170
DV+SG+ G++ Q +AY+LLA YGLY++FF + YF+ GTSRHISVG F V+ L
Sbjct: 87 DVISGVSTGLVATLQGMAYALLAAVPVGYGLYSAFFPILTYFIFGTSRHISVGPFPVVSL 146
Query: 171 MIGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAG 230
M+G V A L SNG T+LN T + +++ S +T + G
Sbjct: 147 MVGSVV--------LSMAPDEHFLVSSSNG-TVLNTTMIDTAARDTARVLIASALTLLVG 197
Query: 231 VYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTW 290
+ Q+ G Q+GF+ YL+D L+ GF T A+F +L SQ K +L ++ NGV S+I T
Sbjct: 198 IIQLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIYTL 257
Query: 291 IHVFRNIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFG 350
+ +F+NI TNL D LL ++V + KELN+ F+ K+ PIPIE++V + AT S+
Sbjct: 258 VEIFQNIGDTNLADFTAGLLTIVVCMAVKELNDRFRHKIPVPIPIEVIVTIIATAISYGA 317
Query: 351 KLHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGY 410
L +NYN+ I IP GF+PP++P +L + + +I+++ +AI VS+ +++A K+ Y
Sbjct: 318 NLEKNYNAGIVKSIPRGFLPPELPPVSLFSEMLAASFSIAVVAYAIAVSVGKVYATKYDY 377
Query: 411 TVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLV 470
T+ NQE A G NI FF CF + AL++T V+ESTG TQ++G+++A ++++ +L
Sbjct: 378 TIDGNQEFIAFGISNIFSGFFSCFVATTALSRTAVQESTGGKTQVAGIISAAIVMIAILA 437
Query: 471 IAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIG 530
+ L LQKSVL + I NL+G + D+P++W +++D VIW T + S +L ++G
Sbjct: 438 LGKLLEPLQKSVLAAVVIANLKGMFMQLCDIPRLWRQNKIDAVIWVFTCIVSIILGLDLG 497
Query: 531 LLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYI 590
LL G+ F + V+LR Q P + LG + +++++S YKN++ G+KI RF +P++Y
Sbjct: 498 LLAGLIFGLLTVVLRVQFPSWNGLGSIPSTDIYKSTKNYKNIEEPQGVKILRFSSPIFYG 557
Query: 591 NKECFKSALYKQTVNPILIKVAWKK-AAKRKIKEKV------VTLGGI------------ 631
N + FK + K TV I+V K+ A RKI++ + T GI
Sbjct: 558 NVDGFKKCI-KSTVGFDAIRVYNKRLKALRKIQKLIKSGQLRATKNGIISDAVSTNNAFE 616
Query: 632 ------------------------QDEMSVQLSHDPLELHTIVIDCSAIQFLDTAGIHTL 667
E+ V+++ + +H++V+DC AI FLD G+ +L
Sbjct: 617 PDEDIEDLEELDIPTKEIEIQVDWNSELPVKVNVPKVPIHSLVLDCGAISFLDVVGVRSL 676
Query: 668 KEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCKKEEENL----LFYSVYEAMAFAEVS- 722
+ + ++++ I + V A V + L E C ++N+ F +V++A+ + +
Sbjct: 677 RVIVKEFQRIDVNVYFASLQDYVIEKL---EQCGFFDDNIRKDTFFLTVHDAILYLQNQV 733
Query: 723 KNQKG 727
K+Q+G
Sbjct: 734 KSQEG 738
>gi|94721257 solute carrier family 26, member 6 isoform 3 [Homo
sapiens]
Length = 740
Score = 419 bits (1078), Expect = e-117
Identities = 231/685 (33%), Positives = 385/685 (56%), Gaps = 66/685 (9%)
Query: 79 QCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPV 138
QCS A+A ++L LPVL WLP+Y ++ +LGD++SGL V I+ +PQ +AY+LLAG PV
Sbjct: 61 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 120
Query: 139 YGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVS 198
+GLY+SF+ IYFL GTSRHISVG F V+ +M+G + SL +
Sbjct: 121 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE---------------SLAPQA 165
Query: 199 NGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVT 258
+++N T+ + + V ST++ + G++QV +G GFV YLS+ L+ G+ T
Sbjct: 166 LNDSMINETA-----RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTT 220
Query: 259 GASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPT 318
A+ + SQ KY+ GL+L +G SLI T + V + ++ + ++T+ + +VL+
Sbjct: 221 AAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVV 280
Query: 319 KELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNL 378
K LN+ + +L PIP EL+ ++ AT S+ L + + G+IP G +PP P L
Sbjct: 281 KLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQL 340
Query: 379 IPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSA 438
+ A I+++GFAI +SL ++FA +HGY V +NQE+ A+G N+I F CF S
Sbjct: 341 FSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSC 400
Query: 439 ALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKF 498
+++++LV+ESTG ++Q++G +++L +LL+++ + LF+ L K+VL I IVNL+G LR+
Sbjct: 401 SMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQL 460
Query: 499 RDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVE 558
D+ +W +R D +IW VT ++ LL+ ++GL+V V FS+ V++RTQ P S+LG V
Sbjct: 461 SDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVP 520
Query: 559 ESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKKAAK 618
+++++ V+ Y + G+K+FR A +Y+ N E + AL ++ + ++ KK K
Sbjct: 521 DTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKK--K 578
Query: 619 RKIKEKVVTLGGIQDEMSVQLSHDPL---------------------------------- 644
K++ + L +Q E ++ PL
Sbjct: 579 LLKKQEQLKLKQLQKEEKLRKQAGPLLSACLAPQQVSSGDKMEDATANGQEDSKAPDGST 638
Query: 645 ---------ELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLT 695
+ H++++D A+ F+DT + +LK + D+ I ++V +A C+ V L
Sbjct: 639 LKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEVEVYMAACHSPVVSQLE 698
Query: 696 NGEYCKKE-EENLLFYSVYEAMAFA 719
G + + LF SV++A+ FA
Sbjct: 699 AGHFFDASITKKHLFASVHDAVTFA 723
>gi|94721255 solute carrier family 26, member 6 isoform 2 [Homo
sapiens]
Length = 758
Score = 412 bits (1060), Expect = e-115
Identities = 228/701 (32%), Positives = 386/701 (55%), Gaps = 80/701 (11%)
Query: 79 QCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPV 138
QCS A+A ++L LPVL WLP+Y ++ +LGD++SGL V I+ +PQ +AY+LLAG PV
Sbjct: 61 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 120
Query: 139 YGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVS 198
+GLY+SF+ IYFL GTSRHISVG F V+ +M+G + SL +
Sbjct: 121 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE---------------SLAPQA 165
Query: 199 NGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVT 258
+++N T+ + + V ST++ + G++QV +G GFV YLS+ L+ G+ T
Sbjct: 166 LNDSMINETA-----RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTT 220
Query: 259 GASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPT 318
A+ + SQ KY+ GL+L +G SLI T + V + ++ + ++T+ + +VL+
Sbjct: 221 AAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVV 280
Query: 319 KELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNL 378
K LN+ + +L PIP EL+ ++ AT S+ L + + G+IP G +PP P L
Sbjct: 281 KLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQL 340
Query: 379 IPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSA 438
+ A I+++GFAI +SL ++FA +HGY V +NQE+ A+G N+I F CF S
Sbjct: 341 FSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSC 400
Query: 439 ALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKF 498
+++++LV+ESTG ++Q++G +++L +LL+++ + LF+ L K+VL I IVNL+G LR+
Sbjct: 401 SMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQL 460
Query: 499 RDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVE 558
D+ +W +R D +IW VT ++ LL+ ++GL+V V FS+ V++RTQ P S+LG V
Sbjct: 461 SDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVP 520
Query: 559 ESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKKAA- 617
+++++ V+ Y + G+K+FR A +Y+ N E + AL ++ + ++ KK
Sbjct: 521 DTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLL 580
Query: 618 -------------KRKIKEKVVTLGGIQDEMSVQLSHDPL-------------------- 644
+ K++++ + G ++V S + +
Sbjct: 581 KKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNNVEDCKMMVSSGDKMED 640
Query: 645 -------------------------ELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGI 679
+ H++++D A+ F+DT + +LK + D+ I +
Sbjct: 641 ATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREIEV 700
Query: 680 QVLLAQCNPTVRDSLTNGEYCKKE-EENLLFYSVYEAMAFA 719
+V +A C+ V L G + + LF SV++A+ FA
Sbjct: 701 EVYMAACHSPVVSQLEAGHFFDASITKKHLFASVHDAVTFA 741
>gi|94721259 solute carrier family 26, member 6 isoform 4 [Homo
sapiens]
Length = 738
Score = 404 bits (1037), Expect = e-112
Identities = 229/703 (32%), Positives = 383/703 (54%), Gaps = 83/703 (11%)
Query: 79 QCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPV 138
QCS A+A ++L LPVL WLP+Y ++ +LGD++SGL V I+ +PQ +AY+LLAG PV
Sbjct: 40 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 99
Query: 139 YGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVS 198
+GLY+SF+ IYFL GTSRHISVG F V+ +M+G + SL +
Sbjct: 100 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE---------------SLAPQA 144
Query: 199 NGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVT 258
+++N T+ + + V ST++ + G++QV +G GFV YLS+ L+ G+ T
Sbjct: 145 LNDSMINETA-----RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTT 199
Query: 259 GASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPT 318
A+ + SQ KY+ GL+L +G SLI T + V + ++ + ++T+ + +VL+
Sbjct: 200 AAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVV 259
Query: 319 KELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNL 378
K LN+ + +L PIP EL+ ++ AT S+ L + + G+IP G +PP P L
Sbjct: 260 KLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQL 319
Query: 379 IPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSA 438
+ A I+++GFAI +SL ++FA +HGY V +NQE+ A+G N+I F CF S
Sbjct: 320 FSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSC 379
Query: 439 ALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKF 498
+++++LV+ESTG ++Q++G +++L +LL+++ + LF+ L K+VL I IVNL+G LR+
Sbjct: 380 SMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQL 439
Query: 499 RDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVE 558
D+ +W +R D +IW VT ++ LL+ ++GL+V V FS+ V++RTQ P S+LG V
Sbjct: 440 SDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVP 499
Query: 559 ESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKK--- 615
+++++ V+ Y + G+K+FR A +Y+ N E + AL ++ + ++ KK
Sbjct: 500 DTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLL 559
Query: 616 -----------AAKRKIKEKVVTLGGIQDEMSVQLSHDPLELHTIVIDCSAIQ------- 657
+ K++++ + G ++V S + + + V DC +Q
Sbjct: 560 KKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNN-VEDCKMMQVSSGDKM 618
Query: 658 ----------------------------------------FLDTAGIHTLKEVRRDYEAI 677
F+DT + +LK + D+ I
Sbjct: 619 EDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREI 678
Query: 678 GIQVLLAQCNPTVRDSLTNGEYCKKE-EENLLFYSVYEAMAFA 719
++V +A C+ V L G + + LF SV++A+ FA
Sbjct: 679 EVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVHDAVTFA 721
>gi|94721253 solute carrier family 26, member 6 isoform 1 [Homo
sapiens]
Length = 759
Score = 404 bits (1037), Expect = e-112
Identities = 229/703 (32%), Positives = 383/703 (54%), Gaps = 83/703 (11%)
Query: 79 QCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPV 138
QCS A+A ++L LPVL WLP+Y ++ +LGD++SGL V I+ +PQ +AY+LLAG PV
Sbjct: 61 QCSRARAYALLLQHLPVLVWLPRYPVRDWLLGDLLSGLSVAIMQLPQGLAYALLAGLPPV 120
Query: 139 YGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVS 198
+GLY+SF+ IYFL GTSRHISVG F V+ +M+G + SL +
Sbjct: 121 FGLYSSFYPVFIYFLFGTSRHISVGTFAVMSVMVGSVTE---------------SLAPQA 165
Query: 199 NGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVT 258
+++N T+ + + V ST++ + G++QV +G GFV YLS+ L+ G+ T
Sbjct: 166 LNDSMINETA-----RDAARVQVASTLSVLVGLFQVGLGLIHFGFVVTYLSEPLVRGYTT 220
Query: 259 GASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPT 318
A+ + SQ KY+ GL+L +G SLI T + V + ++ + ++T+ + +VL+
Sbjct: 221 AAAVQVFVSQLKYVFGLHLSSHSGPLSLIYTVLEVCWKLPQSKVGTVVTAAVAGVVLVVV 280
Query: 319 KELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNL 378
K LN+ + +L PIP EL+ ++ AT S+ L + + G+IP G +PP P L
Sbjct: 281 KLLNDKLQQQLPMPIPGELLTLIGATGISYGMGLKHRFEVDVVGNIPAGLVPPVAPNTQL 340
Query: 379 IPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSA 438
+ A I+++GFAI +SL ++FA +HGY V +NQE+ A+G N+I F CF S
Sbjct: 341 FSKLVGSAFTIAVVGFAIAISLGKIFALRHGYRVDSNQELVALGLSNLIGGIFQCFPVSC 400
Query: 439 ALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKF 498
+++++LV+ESTG ++Q++G +++L +LL+++ + LF+ L K+VL I IVNL+G LR+
Sbjct: 401 SMSRSLVQESTGGNSQVAGAISSLFILLIIVKLGELFHDLPKAVLAAIIIVNLKGMLRQL 460
Query: 499 RDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVE 558
D+ +W +R D +IW VT ++ LL+ ++GL+V V FS+ V++RTQ P S+LG V
Sbjct: 461 SDMRSLWKANRADLLIWLVTFTATILLNLDLGLVVAVIFSLLLVVVRTQMPHYSVLGQVP 520
Query: 559 ESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKK--- 615
+++++ V+ Y + G+K+FR A +Y+ N E + AL ++ + ++ KK
Sbjct: 521 DTDIYRDVAEYSEAKEVRGVKVFRSSATVYFANAEFYSDALKQRCGVDVDFLISQKKKLL 580
Query: 616 -----------AAKRKIKEKVVTLGGIQDEMSVQLSHDPLELHTIVIDCSAIQ------- 657
+ K++++ + G ++V S + + + V DC +Q
Sbjct: 581 KKQEQLKLKQLQKEEKLRKQAASPKGASVSINVNTSLEDMRSNN-VEDCKMMQVSSGDKM 639
Query: 658 ----------------------------------------FLDTAGIHTLKEVRRDYEAI 677
F+DT + +LK + D+ I
Sbjct: 640 EDATANGQEDSKAPDGSTLKALGLPQPDFHSLILDLGALSFVDTVCLKSLKNIFHDFREI 699
Query: 678 GIQVLLAQCNPTVRDSLTNGEYCKKE-EENLLFYSVYEAMAFA 719
++V +A C+ V L G + + LF SV++A+ FA
Sbjct: 700 EVEVYMAACHSPVVSQLEAGHFFDASITKKHLFASVHDAVTFA 742
>gi|4557535 solute carrier family 26, member 3 [Homo sapiens]
Length = 764
Score = 399 bits (1024), Expect = e-111
Identities = 225/712 (31%), Positives = 384/712 (53%), Gaps = 53/712 (7%)
Query: 57 ERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGL 116
E +K+ + K F + L+ C CSP KAK ++L P+ WLP Y LK+ +L D++SG+
Sbjct: 23 ENHKKTGRHHKTF-LDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLKEWLLSDIVSGI 81
Query: 117 IVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETV 176
GI+ V Q +A++LL PVYGLY SFF +IIY GTSRHISVG F +L +M+G V
Sbjct: 82 STGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLAV 141
Query: 177 DRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAM 236
+ KA D + L SN S+LL+ R+ ++VT ++G+ Q+A
Sbjct: 142 SGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVA--------AAASVTVLSGIIQLAF 193
Query: 237 GFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRN 296
G ++GFV +YLS++L+SGF T A+ +L SQ K++ L +P S+ VF
Sbjct: 194 GILRIGFVVIYLSESLISGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQ 253
Query: 297 IHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENY 356
I KTN+ DL+T+L+ LLV+ KE+N+ FK KL PIPIE ++ V A S+ +
Sbjct: 254 IEKTNIADLVTALIVLLVVSIVKEINQRFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRF 313
Query: 357 NSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQ 416
++ G + GF PP P+ + D I+++ FA+ S++ +++ K+ Y + NQ
Sbjct: 314 KVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVAFAVAFSVASVYSLKYDYPLDGNQ 373
Query: 417 EMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFY 476
E+ A+G NI+ F F S AL+++ V+ESTG TQ++G++ A+++L+V+L I L
Sbjct: 374 ELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAIIVLIVVLAIGFLLA 433
Query: 477 SLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVC 536
LQKSVL + + NL+G L +F ++ ++W + D +IW +T + + +L +GL V
Sbjct: 434 PLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAASVA 493
Query: 537 FSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFK 596
F + ++ RTQ PK S L + + ++++ Y ++ G+KIFR +P+Y+ N F+
Sbjct: 494 FQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFR 553
Query: 597 SALYKQT-VNPILIKVAWKKAAK--RKIKEK----------VVTLGGIQ----------- 632
L +P+ I KA + RK++++ + T+ I+
Sbjct: 554 RKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQI 613
Query: 633 -------------------DEMSVQLSHDPLELHTIVIDCSAIQFLDTAGIHTLKEVRRD 673
D++ + + + LH++++D SA+ FLD + + LK + ++
Sbjct: 614 EVLDQPINTTDLPFHIDWNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQE 673
Query: 674 YEAIGIQVLLAQCNPTVRDSLTNGEYCKKE-EENLLFYSVYEAMAFAEVSKN 724
+ I + V + + + L E+ E + ++ F ++++A+ + K+
Sbjct: 674 FIRIKVDVYIVGTDDDFIEKLNRYEFFDGEVKSSIFFLTIHDAVLHILMKKD 725
>gi|45827802 prestin isoform c [Homo sapiens]
Length = 516
Score = 378 bits (970), Expect = e-104
Identities = 199/496 (40%), Positives = 297/496 (59%), Gaps = 16/496 (3%)
Query: 52 HRILIERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGD 111
H +L ER D + + KL++ C+P K +N+I FLP+ +WLP Y K+ +LGD
Sbjct: 25 HPVLQERLHTKD-KVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGD 83
Query: 112 VMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLM 171
++SG+ G+L +PQ +A+++LA P++GLY+SF+ I+Y LGTSRHIS+G F V+ LM
Sbjct: 84 LVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLM 143
Query: 172 IGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGV 231
IG R + P ++ G N T R + V +VT ++G+
Sbjct: 144 IGGVAVRLV-----------PDDIVIPGGVNATNGTEAR----DALRVKVAMSVTLLSGI 188
Query: 232 YQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWI 291
Q +G + GFV++YL++ L+ GF T A+ + TS KYL G+ R +G+ S++ + +
Sbjct: 189 IQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTV 248
Query: 292 HVFRNIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGK 351
V +N+ N+C L L+ +LL KE NE FK KL APIP+E VV T S
Sbjct: 249 AVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFN 308
Query: 352 LHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYT 411
L E+YN + G +P G +PP P+ +L V VDAIAI+I+GF++T+S+++ A KHGY
Sbjct: 309 LKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQ 368
Query: 412 VKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVI 471
V NQE+ A+G CN I S F F+ S +L+++LV+E TG TQL+G + +L++LLV+L
Sbjct: 369 VDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILAT 428
Query: 472 APLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGL 531
LF SL ++VL I IVNL+G +F DLP W S+++ IW T +SS L + GL
Sbjct: 429 GFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGL 488
Query: 532 LVGVCFSIFCVILRTQ 547
+ V ++ VI RTQ
Sbjct: 489 ITAVIIALLTVIYRTQ 504
>gi|16418413 solute carrier family 26, member 9 isoform a [Homo
sapiens]
Length = 791
Score = 358 bits (919), Expect = 1e-98
Identities = 220/730 (30%), Positives = 365/730 (50%), Gaps = 81/730 (11%)
Query: 60 EKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVG 119
EK D + V +KL+ +CS AK K ++ G LPVL WLPKY +K I+ D++ GL G
Sbjct: 25 EKKDRTYP--VGEKLRNAFRCSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGG 82
Query: 120 ILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRE 179
+ VPQ +A++LLA V GLY+SFF + YF LG + G F V+ +++G +
Sbjct: 83 SIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNICLQL 142
Query: 180 LQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFF 239
++ + ++A + V + + V +T+ + + Q+ +GF
Sbjct: 143 APESKFQVFNNATNESYVDTAAM------------EAERLHVSATLACLTAIIQMGLGFM 190
Query: 240 QVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHK 299
Q GFV++YLS++ + GF+T A IL S KY+ GL +P G GS++ T+I + +N+
Sbjct: 191 QFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPH 250
Query: 300 TNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSS 359
TN+ LI +L+ L+ KELN + K++ PIP E++VVV AT S K+ + Y+
Sbjct: 251 TNIASLIFALISGAFLVLVKELNARYMHKIRFPIPTEMIVVVVATAISGGCKMPKKYHMQ 310
Query: 360 IAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMY 419
I G I GF P P + + A +++I+ + I +++ A KHGY V +NQEM
Sbjct: 311 IVGEIQRGFPTPVSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMI 370
Query: 420 AIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQ 479
A+G N SFF AL+ TL + G +Q++ + +LV+++ +LV+ Y L
Sbjct: 371 ALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLP 430
Query: 480 KSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSI 539
KSVLG + VNL+ +L++ D +W S++D IW V+ LSS LS G+ VGV FS+
Sbjct: 431 KSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSV 490
Query: 540 FCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSAL 599
V+ +TQ L V +++++ + Y Q GIKI + +PLY+ N E F+ +
Sbjct: 491 LVVVFQTQFRNGYALAQVMDTDIYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKV 550
Query: 600 YKQT-VNPILIKVAWKKAAKRK---------------IKEKVVTLGGIQDEMSVQLSHDP 643
+T ++P + +A +K K++ +K K V+L +Q + DP
Sbjct: 551 IAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDP 610
Query: 644 -------------------------------------------------LELHTIVIDCS 654
+ HT+++D S
Sbjct: 611 NNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMS 670
Query: 655 AIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCK--KEEENLLFYSV 712
+ F+D GI L ++ Y IG++V L + V + +++G + E +F S+
Sbjct: 671 GVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSI 730
Query: 713 YEAMAFAEVS 722
++A+ FA+ +
Sbjct: 731 HDAVLFAQAN 740
>gi|217272867 solute carrier family 26, member 9 isoform b [Homo
sapiens]
Length = 887
Score = 358 bits (919), Expect = 1e-98
Identities = 220/730 (30%), Positives = 365/730 (50%), Gaps = 81/730 (11%)
Query: 60 EKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVG 119
EK D + V +KL+ +CS AK K ++ G LPVL WLPKY +K I+ D++ GL G
Sbjct: 25 EKKDRTYP--VGEKLRNAFRCSSAKIKAVVFGLLPVLSWLPKYKIKDYIIPDLLGGLSGG 82
Query: 120 ILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRE 179
+ VPQ +A++LLA V GLY+SFF + YF LG + G F V+ +++G +
Sbjct: 83 SIQVPQGMAFALLANLPAVNGLYSSFFPLLTYFFLGGVHQMVPGTFAVISILVGNICLQL 142
Query: 180 LQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFF 239
++ + ++A + V + + V +T+ + + Q+ +GF
Sbjct: 143 APESKFQVFNNATNESYVDTAAM------------EAERLHVSATLACLTAIIQMGLGFM 190
Query: 240 QVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHK 299
Q GFV++YLS++ + GF+T A IL S KY+ GL +P G GS++ T+I + +N+
Sbjct: 191 QFGFVAIYLSESFIRGFMTAAGLQILISVLKYIFGLTIPSYTGPGSIVFTFIDICKNLPH 250
Query: 300 TNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSS 359
TN+ LI +L+ L+ KELN + K++ PIP E++VVV AT S K+ + Y+
Sbjct: 251 TNIASLIFALISGAFLVLVKELNARYMHKIRFPIPTEMIVVVVATAISGGCKMPKKYHMQ 310
Query: 360 IAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMY 419
I G I GF P P + + A +++I+ + I +++ A KHGY V +NQEM
Sbjct: 311 IVGEIQRGFPTPVSPVVSQWKDMIGTAFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMI 370
Query: 420 AIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQ 479
A+G N SFF AL+ TL + G +Q++ + +LV+++ +LV+ Y L
Sbjct: 371 ALGCSNFFGSFFKIHVICCALSVTLAVDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLP 430
Query: 480 KSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSI 539
KSVLG + VNL+ +L++ D +W S++D IW V+ LSS LS G+ VGV FS+
Sbjct: 431 KSVLGALIAVNLKNSLKQLTDPYYLWRKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSV 490
Query: 540 FCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSAL 599
V+ +TQ L V +++++ + Y Q GIKI + +PLY+ N E F+ +
Sbjct: 491 LVVVFQTQFRNGYALAQVMDTDIYVNPKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKV 550
Query: 600 YKQT-VNPILIKVAWKKAAKRK---------------IKEKVVTLGGIQDEMSVQLSHDP 643
+T ++P + +A +K K++ +K K V+L +Q + DP
Sbjct: 551 IAKTGMDPQKVLLAKQKYLKKQEKRRMRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDP 610
Query: 644 -------------------------------------------------LELHTIVIDCS 654
+ HT+++D S
Sbjct: 611 NNNQTPANGTSVSYITFSPDSSSPAQSEPPASAEAPGEPSDMLASVPPFVTFHTLILDMS 670
Query: 655 AIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPTVRDSLTNGEYCK--KEEENLLFYSV 712
+ F+D GI L ++ Y IG++V L + V + +++G + E +F S+
Sbjct: 671 GVSFVDLMGIKALAKLSSTYGKIGVKVFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSI 730
Query: 713 YEAMAFAEVS 722
++A+ FA+ +
Sbjct: 731 HDAVLFAQAN 740
>gi|16306483 solute carrier family 26, member 7 isoform a [Homo
sapiens]
Length = 656
Score = 342 bits (876), Expect = 1e-93
Identities = 206/639 (32%), Positives = 342/639 (53%), Gaps = 31/639 (4%)
Query: 93 LPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYF 152
LP+L W P Y+LK+N+L D +SG+++ + V Q +A+++L+ PV+GLY S F +IIY
Sbjct: 32 LPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIYA 91
Query: 153 LLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRIC 212
+ G H++ G F + L+ V+R + + + +L SN S L +
Sbjct: 92 IFGMGHHVATGTFALTSLISANAVERIVPQ-------NMQNLTTQSNTSVL------GLS 138
Query: 213 DKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYL 272
D I V + V+F+ GV QVAM Q+G + +++ ++S TGA+ ++TSQ KYL
Sbjct: 139 DFEMQRIHVAAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYL 198
Query: 273 LGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAP 332
LG+ +P +G + +VF NI L L+ SLL ++VL+ KELNE FK K+K
Sbjct: 199 LGMKMPYISGPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVV 258
Query: 333 IPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISII 392
+P++LV+++AA+ A + + Y + GHIP G P+ P N++ +V +A ++++
Sbjct: 259 LPVDLVLIIAASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALV 318
Query: 393 GFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCH 452
G+ +++L++ AKK Y++ NQE A G NI+ SFF C ++AA+ +T STG
Sbjct: 319 GYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAK 378
Query: 453 TQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDT 512
TQ++ +++ + +L+V+ I PL Y L VL I +V L+G L +FRDL K W++ ++D
Sbjct: 379 TQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDW 438
Query: 513 VIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNL 572
IW T + + + +GLL GV +I VI R P++ + + E+ V +
Sbjct: 439 GIWVSTYVFTICFAANVGLLFGVVCTIAIVIGRF--PRAMTVSIKNMKEMEFKVKTEMDS 496
Query: 573 QIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKKAAKRKIKEKVVTL---- 628
+ +KI PL ++N + F Y +N I + A + K + TL
Sbjct: 497 ETLQQVKIISINNPLVFLNAKKF----YTDLMNMIQKENACNQPLDDISKCEQNTLLNSL 552
Query: 629 --GGIQDEMSVQLSHDPLELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQC 686
G +E S P E +++DCS F D +G+ L EV D + + VLLA C
Sbjct: 553 SNGNCNEEASQSC---PNEKCYLILDCSGFTFFDYSGVSMLVEVYMDCKGRSVDVLLAHC 609
Query: 687 NPTVRDSLTNGEYCKKEEENLLFY-SVYEAMAFAEVSKN 724
++ ++T Y + E +F+ SV A++ +KN
Sbjct: 610 TASLIKAMT--YYGNLDSEKPIFFESVSAAISHIHSNKN 646
>gi|20336282 solute carrier family 26, member 7 isoform b [Homo
sapiens]
Length = 663
Score = 340 bits (872), Expect = 3e-93
Identities = 204/639 (31%), Positives = 340/639 (53%), Gaps = 31/639 (4%)
Query: 93 LPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYF 152
LP+L W P Y+LK+N+L D +SG+++ + V Q +A+++L+ PV+GLY S F +IIY
Sbjct: 32 LPILDWAPHYNLKENLLPDTVSGIMLAVQQVTQGLAFAVLSSVHPVFGLYGSLFPAIIYA 91
Query: 153 LLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRIC 212
+ G H++ G F + L+ V+R + + + +L SN S L +
Sbjct: 92 IFGMGHHVATGTFALTSLISANAVERIVPQ-------NMQNLTTQSNTSVL------GLS 138
Query: 213 DKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYL 272
D I V + V+F+ GV QVAM Q+G + +++ ++S TGA+ ++TSQ KYL
Sbjct: 139 DFEMQRIHVAAAVSFLGGVIQVAMFVLQLGSATFVVTEPVISAMTTGAATHVVTSQVKYL 198
Query: 273 LGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAP 332
LG+ +P +G + +VF NI L L+ SLL ++VL+ KELNE FK K+K
Sbjct: 199 LGMKMPYISGPLGFFYIYAYVFENIKSVRLEALLLSLLSIVVLVLVKELNEQFKRKIKVV 258
Query: 333 IPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISII 392
+P++LV+++AA+ A + + Y + GHIP G P+ P N++ +V +A ++++
Sbjct: 259 LPVDLVLIIAASFACYCTNMENTYGLEVVGHIPQGIPSPRAPPMNILSAVITEAFGVALV 318
Query: 393 GFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCH 452
G+ +++L++ AKK Y++ NQE A G NI+ SFF C ++AA+ +T STG
Sbjct: 319 GYVASLALAQGSAKKFKYSIDDNQEFLAHGLSNIVSSFFFCIPSAAAMGRTAGLYSTGAK 378
Query: 453 TQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDT 512
TQ++ +++ + +L+V+ I PL Y L VL I +V L+G L +FRDL K W++ ++D
Sbjct: 379 TQVACLISCIFVLIVIYAIGPLLYWLPMCVLASIIVVGLKGMLIQFRDLKKYWNVDKIDW 438
Query: 513 VIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNL 572
IW T + + + +GLL GV +I VI R P++ + + E+ V +
Sbjct: 439 GIWVSTYVFTICFAANVGLLFGVVCTIAIVIGRF--PRAMTVSIKNMKEMEFKVKTEMDS 496
Query: 573 QIKPGIKIFRFVAPLYYINKECFKSALYKQTVNPILIKVAWKKAAKRKIKEKVVTL---- 628
+ +KI PL ++N + F Y +N I + A + K + TL
Sbjct: 497 ETLQQVKIISINNPLVFLNAKKF----YTDLMNMIQKENACNQPLDDISKCEQNTLLNSL 552
Query: 629 --GGIQDEMSVQLSHDPLELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQC 686
G +E S P E +++DCS F D +G+ L EV D + + VLLA C
Sbjct: 553 SNGNCNEEASQSC---PNEKCYLILDCSGFTFFDYSGVSMLVEVYMDCKGRSVDVLLAHC 609
Query: 687 NPTVRDSLTNGEYCKKEEENLLFYSVYEAMAFAEVSKNQ 725
++ ++T Y + E +F+ A A + + N+
Sbjct: 610 TASLIKAMT--YYGNLDSEKPIFFESVSA-AISHIHSNK 645
>gi|16418457 solute carrier family 26, member 8 isoform a [Homo
sapiens]
Length = 970
Score = 253 bits (647), Expect = 3e-67
Identities = 145/534 (27%), Positives = 279/534 (52%), Gaps = 27/534 (5%)
Query: 78 CQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQ-- 135
C+CS + +L P L+W+ Y LK +LGD+++G+ VG++ VPQ + SLLA Q
Sbjct: 62 CRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLI 121
Query: 136 EPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETV------DRELQKAGY-DNA 188
P+ Y +F +S+IY + G+ +S+G F ++ ++ + + +L + N
Sbjct: 122 PPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKNE 181
Query: 189 HSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYL 248
SAPS M N S + V +T TF+ G+ Q+ MG +GF++ YL
Sbjct: 182 FSAPSYLMGYNKS-----------------LSVVATTTFLTGIIQLIMGVLGLGFIATYL 224
Query: 249 SDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLITS 308
++ +S ++ + I+ SQ ++ G+ + G S I+ + K N ++
Sbjct: 225 PESAMSAYLAAVALHIMLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVF 284
Query: 309 LLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPTGF 368
L ++ L K + F ++ P+EL +++ T+ ++ + + ++ IP F
Sbjct: 285 LTVVVALRINKCIRISF-NQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSF 343
Query: 369 MPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIP 428
+ P P+++L+P + + A ++S++ + + L + A H Y+V +NQ++ AIG CN++
Sbjct: 344 LLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVS 403
Query: 429 SFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITI 488
SFF + A+A+T++++ +G Q + +V A V+LL+++ + FY+L +VL I +
Sbjct: 404 SFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIIL 463
Query: 489 VNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQK 548
N+ L +LP +W + D +W +T SS L +IGL++ V + F +R+ +
Sbjct: 464 SNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHR 523
Query: 549 PKSSLLGLVEESEVFESVSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQ 602
K LLG + + ++ S++ Y+ + PG+KIF+ + + ++N K L K+
Sbjct: 524 AKILLLGQIPNTNIYRSINDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKE 577
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/75 (29%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Query: 646 LHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPT-VRDSLTNGEYCKKEE 704
+HTI++D S + ++D+ G+ L+++ ++ I +L+A C+ + VR N +
Sbjct: 721 VHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGIT 780
Query: 705 ENLLFYSVYEAMAFA 719
+ LF SV++A+ FA
Sbjct: 781 KTQLFLSVHDAVLFA 795
>gi|65506789 solute carrier family 26, member 10 [Homo sapiens]
Length = 563
Score = 247 bits (631), Expect = 2e-65
Identities = 141/388 (36%), Positives = 217/388 (55%), Gaps = 18/388 (4%)
Query: 127 IAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYD 186
+A++LLA PV+GLYTSFF +IY LLGT RH+S G F +L LM G V+R + +
Sbjct: 42 MAFALLASVPPVFGLYTSFFPVLIYSLLGTGRHLSTGTFAILSLMTGSAVERLVPEP--- 98
Query: 187 NAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSV 246
+V N S + D + V + V F +G + M Q+G +S
Sbjct: 99 ---------LVGNLSGIEKEQLD------AQRVGVAAAVAFGSGALMLGMFVLQLGVLST 143
Query: 247 YLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWIHVFRNIHKTNLCDLI 306
+LS+ ++ +GA+ +L SQ LLGL+LPR G SL T + + +++ +L
Sbjct: 144 FLSEPVVKALTSGAALHVLLSQLPSLLGLSLPRQIGCFSLFKTLASLLTALPRSSPAELT 203
Query: 307 TSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGKLHENYNSSIAGHIPT 366
S L L +L+P KELN F+ +L PIP E+V+V+ A++ + Y I G +P
Sbjct: 204 ISALSLALLVPVKELNVRFRDRLPTPIPGEVVLVLLASVLCFTSSVDTRYQVQIVGLLPG 263
Query: 367 GFMPPKVPEWNLIPSVAVDAIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNI 426
GF P +P +P + D++ I+++ FA++ SL+ + A K+ YT+ +NQE A G N+
Sbjct: 264 GFPQPLLPNLAELPRILADSLPIALVSFAVSASLASIHADKYSYTIDSNQEFLAHGASNL 323
Query: 427 IPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVI 486
I S F CF SA LA T + G TQL+G+ + V+L VLL + P FY L K+VL I
Sbjct: 324 ISSLFSCFPNSATLATTNLLVDAGGKTQLAGLFSCTVVLSVLLWLGPFFYYLPKAVLACI 383
Query: 487 TIVNLRGALRKFRDLPKMWSISRMDTVI 514
I ++R + ++LP++W ISR+D ++
Sbjct: 384 NISSMRQVFCQMQELPQLWHISRVDFLL 411
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 646 LHTIVIDCSAIQFLDTAGIHTLKEVRRDYEA----IGIQVLLAQCNPTVRDSLTNGEYCK 701
+ +V+D S + F D AG + +VR + I++LLAQCN V+ +LT
Sbjct: 464 VRVVVLDFSGVTFADAAGAREVVQVRERLASRCRDARIRLLLAQCNALVQGTLTRVGLLD 523
Query: 702 KEEENLLFYSVYEAMAFA 719
+ + LF SV +A A+A
Sbjct: 524 RVTPDQLFVSVQDAAAYA 541
>gi|45827804 prestin isoform d [Homo sapiens]
Length = 335
Score = 222 bits (565), Expect = 1e-57
Identities = 120/325 (36%), Positives = 181/325 (55%), Gaps = 16/325 (4%)
Query: 52 HRILIERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGD 111
H +L ER D + + KL++ C+P K +N+I FLP+ +WLP Y K+ +LGD
Sbjct: 25 HPVLQERLHTKD-KVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGD 83
Query: 112 VMSGLIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLM 171
++SG+ G+L +PQ +A+++LA P++GLY+SF+ I+Y LGTSRHIS+G F V+ LM
Sbjct: 84 LVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLM 143
Query: 172 IGETVDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGV 231
IG R + P ++ G N T R + V +VT ++G+
Sbjct: 144 IGGVAVRLV-----------PDDIVIPGGVNATNGTEAR----DALRVKVAMSVTLLSGI 188
Query: 232 YQVAMGFFQVGFVSVYLSDALLSGFVTGASFTILTSQAKYLLGLNLPRTNGVGSLITTWI 291
Q +G + GFV++YL++ L+ GF T A+ + TS KYL G+ R +G+ S++ + +
Sbjct: 189 IQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTV 248
Query: 292 HVFRNIHKTNLCDLITSLLCLLVLLPTKELNEHFKSKLKAPIPIELVVVVAATLASHFGK 351
V +N+ N+C L L+ +LL KE NE FK KL APIP+E VV T S
Sbjct: 249 AVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFN 308
Query: 352 LHENYNSSIAGHIPTGFMPPKVPEW 376
L E+YN + G +P GF W
Sbjct: 309 LKESYNVDVVGTLPLGFHTEMTRRW 333
>gi|85540447 solute carrier family 26, member 11 [Homo sapiens]
Length = 606
Score = 182 bits (461), Expect = 1e-45
Identities = 132/505 (26%), Positives = 237/505 (46%), Gaps = 81/505 (16%)
Query: 78 CQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQEP 137
C CSPA + LP+L WLP Y L+ + D ++GL VG+ +PQ++AY+ +AG P
Sbjct: 23 CCCSPAALQRR----LPILAWLPSYSLQW-LKMDFVAGLSVGLTAIPQALAYAEVAGLPP 77
Query: 138 VYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGETVDRELQKAGYDNAHSAPSLGMV 197
YGLY++F +YF LGTSR +++G ++ L++ E
Sbjct: 78 QYGLYSAFMGCFVYFFLGTSRDVTLGPTAIMSLLVSFYTFHE------------------ 119
Query: 198 SNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGFFQVGFVSVYLSDALLSGFV 257
YA+++ F++G Q+AMG ++GF+ ++S ++ GF
Sbjct: 120 -----------------PAYAVLLA----FLSGCIQLAMGVLRLGFLLDFISYPVIKGFT 158
Query: 258 TGASFTILTSQAKYLLGL-NLPRTNGVGSLITTWIHVFRNIHKTNLCDLITSLLCLLVLL 316
+ A+ TI Q K LLGL N+PR H F I +T + D + L+C+L+LL
Sbjct: 159 SAAAVTIGFGQIKNLLGLQNIPRP-----FFLQVYHTFLRIAETRVGDAVLGLVCMLLLL 213
Query: 317 PTKELNEHFKS---KLKAPIPIELVVVVAATLASH-----FGKLHENYNSSIAGHIP--- 365
K + +H ++ + + +V AAT A + F L Y+ + G+ P
Sbjct: 214 VLKLMRDHVPPVHPEMPPGVRLSRGLVWAATTARNALVVSFAALVA-YSFEVTGYQPFIL 272
Query: 366 -----TGFMPPKVPEWN------------LIPSVAVDAIAISIIGFAITVSLSEMFAKKH 408
G P ++P ++ ++ + + ++G ++++++ FA ++
Sbjct: 273 TGETAEGLPPVRIPPFSVTTANGTISFTEMVQDMGAGLAVVPLMGLLESIAVAKAFASQN 332
Query: 409 GYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLSGVVTALVLLLVL 468
Y + ANQE+ AIG N++ S + + + +T V +G T G+VT +++LL L
Sbjct: 333 NYRIDANQELLAIGLTNMLGSLVSSYPVTGSFGRTAVNAQSGVCTPAGGLVTGVLVLLSL 392
Query: 469 LVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTE 528
+ LFY + KS L + I+ + L + +W + R+D + VT L +
Sbjct: 393 DYLTSLFYYIPKSALAAVIIMAV-APLFDTKIFRTLWRVKRLDLLPLCVTFL-LCFWEVQ 450
Query: 529 IGLLVGVCFSIFCVILRTQKPKSSL 553
G+L G S+ ++ +P++ +
Sbjct: 451 YGILAGALVSLLMLLHSAARPETKV 475
>gi|20336274 solute carrier family 26, member 1 isoform b [Homo
sapiens]
Length = 224
Score = 179 bits (454), Expect = 8e-45
Identities = 86/182 (47%), Positives = 123/182 (67%), Gaps = 2/182 (1%)
Query: 56 IERQEKSDTNFKEFVIKKLQKNCQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSG 115
+ RQ + +E + +L +C CS + ++ LP +WL +Y ++ + GDVMSG
Sbjct: 17 VRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSG 76
Query: 116 LIVGILLVPQSIAYSLLAGQEPVYGLYTSFFASIIYFLLGTSRHISVGIFGVLCLMIGET 175
L++GI+LVPQ+IAYSLLAG +P+Y LYTSFFA++IYFL+GTSRH+SVGIF +LCLM+G+
Sbjct: 77 LVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQV 136
Query: 176 VDRELQKAGYDNAHSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVA 235
VDRELQ AG+D + G +N STL + C + CYAI V + +T + G+YQ +
Sbjct: 137 VDRELQLAGFDPSQDGLQPG--ANSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQTS 194
Query: 236 MG 237
G
Sbjct: 195 WG 196
>gi|217272870 solute carrier family 26, member 9 isoform c [Homo
sapiens]
Length = 459
Score = 169 bits (427), Expect = 1e-41
Identities = 109/404 (26%), Positives = 190/404 (47%), Gaps = 67/404 (16%)
Query: 386 AIAISIIGFAITVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLV 445
A +++I+ + I +++ A KHGY V +NQEM A+G N SFF AL+ TL
Sbjct: 5 AFSLAIVSYVINLAMGRTLANKHGYDVDSNQEMIALGCSNFFGSFFKIHVICCALSVTLA 64
Query: 446 KESTGCHTQLSGVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMW 505
+ G +Q++ + +LV+++ +LV+ Y L KSVLG + VNL+ +L++ D +W
Sbjct: 65 VDGAGGKSQVASLCVSLVVMITMLVLGIYLYPLPKSVLGALIAVNLKNSLKQLTDPYYLW 124
Query: 506 SISRMDTVIWFVTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFES 565
S++D IW V+ LSS LS G+ VGV FS+ V+ +TQ L V +++++ +
Sbjct: 125 RKSKLDCCIWVVSFLSSFFLSLPYGVAVGVAFSVLVVVFQTQFRNGYALAQVMDTDIYVN 184
Query: 566 VSAYKNLQIKPGIKIFRFVAPLYYINKECFKSALYKQT-VNPILIKVAWKKAAKRK---- 620
Y Q GIKI + +PLY+ N E F+ + +T ++P + +A +K K++
Sbjct: 185 PKTYNRAQDIQGIKIITYCSPLYFANSEIFRQKVIAKTGMDPQKVLLAKQKYLKKQEKRR 244
Query: 621 -----------IKEKVVTLGGIQDEMSVQLSHDP-------------------------- 643
+K K V+L +Q + DP
Sbjct: 245 MRPTQQRRSLFMKTKTVSLQELQQDFENAPPTDPNNNQTPANGTSVSYITFSPDSSSPAQ 304
Query: 644 -----------------------LELHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQ 680
+ HT+++D S + F+D GI L ++ Y IG++
Sbjct: 305 SEPPASAEAPGEPSDMLASVPPFVTFHTLILDMSGVSFVDLMGIKALAKLSSTYGKIGVK 364
Query: 681 VLLAQCNPTVRDSLTNGEYCK--KEEENLLFYSVYEAMAFAEVS 722
V L + V + +++G + E +F S+++A+ FA+ +
Sbjct: 365 VFLVNIHAQVYNDISHGGVFEDGSLECKHVFPSIHDAVLFAQAN 408
>gi|20336285 solute carrier family 26, member 8 isoform b [Homo
sapiens]
Length = 865
Score = 158 bits (399), Expect = 2e-38
Identities = 73/266 (27%), Positives = 150/266 (56%)
Query: 337 LVVVVAATLASHFGKLHENYNSSIAGHIPTGFMPPKVPEWNLIPSVAVDAIAISIIGFAI 396
++ ++ T+ ++ + + ++ IP F+ P P+++L+P + + A ++S++ +
Sbjct: 207 IIQIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFL 266
Query: 397 TVSLSEMFAKKHGYTVKANQEMYAIGFCNIIPSFFHCFTTSAALAKTLVKESTGCHTQLS 456
+ L + A H Y+V +NQ++ AIG CN++ SFF + A+A+T++++ +G Q +
Sbjct: 267 LIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFA 326
Query: 457 GVVTALVLLLVLLVIAPLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWF 516
+V A V+LL+++ + FY+L +VL I + N+ L +LP +W + D +W
Sbjct: 327 SLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWM 386
Query: 517 VTMLSSALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGLVEESEVFESVSAYKNLQIKP 576
+T SS L +IGL++ V + F +R+ + K LLG + + ++ S++ Y+ + P
Sbjct: 387 MTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIP 446
Query: 577 GIKIFRFVAPLYYINKECFKSALYKQ 602
G+KIF+ + + ++N K L K+
Sbjct: 447 GVKIFQCCSSITFVNVYYLKHKLLKE 472
Score = 71.6 bits (174), Expect = 2e-12
Identities = 52/170 (30%), Positives = 85/170 (50%), Gaps = 27/170 (15%)
Query: 78 CQCSPAKAKNMILGFLPVLQWLPKYDLKKNILGDVMSGLIVGILLVPQSIAYSLLAGQ-- 135
C+CS + +L P L+W+ Y LK +LGD+++G+ VG++ VPQ + SLLA Q
Sbjct: 62 CRCSWHRFLRCMLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLI 121
Query: 136 EPVYGLYTSFFASIIYFLLGTSRHISVGIFGVL------CLMIGETVDRELQKAGY-DNA 188
P+ Y +F +S+IY + G+ +S+G F ++ L + + +L + N
Sbjct: 122 PPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKNE 181
Query: 189 HSAPSLGMVSNGSTLLNHTSDRICDKSCYAIMVGSTVTFIAGVYQVAMGF 238
SAPS M N S + V +T TF+ G+ Q+ +GF
Sbjct: 182 FSAPSYLMGYNKS-----------------LSVVATTTFLTGIIQI-IGF 213
Score = 42.0 bits (97), Expect = 0.002
Identities = 22/75 (29%), Positives = 44/75 (58%), Gaps = 1/75 (1%)
Query: 646 LHTIVIDCSAIQFLDTAGIHTLKEVRRDYEAIGIQVLLAQCNPT-VRDSLTNGEYCKKEE 704
+HTI++D S + ++D+ G+ L+++ ++ I +L+A C+ + VR N +
Sbjct: 616 VHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGIT 675
Query: 705 ENLLFYSVYEAMAFA 719
+ LF SV++A+ FA
Sbjct: 676 KTQLFLSVHDAVLFA 690
>gi|52317249 olfactory receptor, family 4, subfamily K, member 14
[Homo sapiens]
Length = 310
Score = 34.3 bits (77), Expect = 0.43
Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 14/137 (10%)
Query: 498 FRDLPKMWSISRMDTVIWFVTMLS-SALLSTEIGLLVGVCFSIFCVILRTQKPKSSLLGL 556
F DLP + ++ MDT + + M+S S LLS LL+ + +++ + +R + S+
Sbjct: 179 FCDLPLVIKLACMDTYVLGIIMISDSGLLSLSCFLLLLISYTVILLAIRQRAAGST---- 234
Query: 557 VEESEVFESVSAY-KNLQIKPGIKIFRFVAPLYYINKECFKSALY---KQTVNPIL--IK 610
S+ + SA+ + + G IF +V P + + S Y +NPI+ ++
Sbjct: 235 ---SKALSTCSAHIMVVTLFFGPCIFVYVRPFSRFSVDKLLSVFYTIFTPLLNPIIYTLR 291
Query: 611 VAWKKAAKRKIKEKVVT 627
KAA +K++ + VT
Sbjct: 292 NEEMKAAMKKLQNRRVT 308
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 32.7 bits (73), Expect = 1.2
Identities = 25/108 (23%), Positives = 54/108 (50%), Gaps = 10/108 (9%)
Query: 542 VILRTQKPKSSLLGLVEESEVFE----------SVSAYKNLQIKPGIKIFRFVAPLYYIN 591
+I RTQ L VE + E ++ ++ N++ P +K+F + PL
Sbjct: 790 LITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSA 849
Query: 592 KECFKSALYKQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEMSVQL 639
+ + A K+ I ++A +A +++++EK+VTL ++++ +Q+
Sbjct: 850 ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQV 897
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 32.7 bits (73), Expect = 1.2
Identities = 25/108 (23%), Positives = 54/108 (50%), Gaps = 10/108 (9%)
Query: 542 VILRTQKPKSSLLGLVEESEVFE----------SVSAYKNLQIKPGIKIFRFVAPLYYIN 591
+I RTQ L VE + E ++ ++ N++ P +K+F + PL
Sbjct: 790 LITRTQARCRGFLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSA 849
Query: 592 KECFKSALYKQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEMSVQL 639
+ + A K+ I ++A +A +++++EK+VTL ++++ +Q+
Sbjct: 850 ETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQV 897
>gi|57165415 dolichyl pyrophosphate Glc1Man9GlcNAc2
alpha-1,3-glucosyltransferase isoform b [Homo sapiens]
Length = 467
Score = 32.7 bits (73), Expect = 1.2
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 472 APLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGL 531
AP F++L ++ V++++ L+ ++PK S + + S L+T I
Sbjct: 282 APNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICT 341
Query: 532 LVGVCFSIFCVILRTQKPKSSL 553
L+ + SIFC+ + Q P+ L
Sbjct: 342 LIAILPSIFCLWFKPQGPRGFL 363
>gi|56121818 dolichyl pyrophosphate Glc1Man9GlcNAc2
alpha-1,3-glucosyltransferase isoform a [Homo sapiens]
Length = 526
Score = 32.7 bits (73), Expect = 1.2
Identities = 21/82 (25%), Positives = 40/82 (48%)
Query: 472 APLFYSLQKSVLGVITIVNLRGALRKFRDLPKMWSISRMDTVIWFVTMLSSALLSTEIGL 531
AP F++L ++ V++++ L+ ++PK S + + S L+T I
Sbjct: 282 APNFWALYNALDKVLSVIGLKLKFLDPNNIPKASMTSGLVQQFQHTVLPSVTPLATLICT 341
Query: 532 LVGVCFSIFCVILRTQKPKSSL 553
L+ + SIFC+ + Q P+ L
Sbjct: 342 LIAILPSIFCLWFKPQGPRGFL 363
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal
[Homo sapiens]
Length = 1937
Score = 32.0 bits (71), Expect = 2.1
Identities = 25/111 (22%), Positives = 55/111 (49%), Gaps = 10/111 (9%)
Query: 542 VILRTQKPKSSLLGLVEESEVFE----------SVSAYKNLQIKPGIKIFRFVAPLYYIN 591
+I RTQ L VE ++ + +V A+ N++ P +K+F + PL
Sbjct: 787 IITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSA 846
Query: 592 KECFKSALYKQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEMSVQLSHD 642
+ + A K+ ++A +A +++++EK+VTL ++++ +Q+ +
Sbjct: 847 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSE 897
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 30.8 bits (68), Expect = 4.7
Identities = 25/108 (23%), Positives = 54/108 (50%), Gaps = 10/108 (9%)
Query: 542 VILRTQKPKSSLLGLVEESEVFE----------SVSAYKNLQIKPGIKIFRFVAPLYYIN 591
+I RTQ L VE ++ E +V A+ N++ P +K++ + PL
Sbjct: 788 LITRTQAMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSA 847
Query: 592 KECFKSALYKQTVNPILIKVAWKKAAKRKIKEKVVTLGGIQDEMSVQL 639
+ + A K+ ++A +A +++++EK+VTL ++++ +Q+
Sbjct: 848 ETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQV 895
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,083,286
Number of Sequences: 37866
Number of extensions: 1033669
Number of successful extensions: 2406
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2324
Number of HSP's gapped (non-prelim): 52
length of query: 739
length of database: 18,247,518
effective HSP length: 110
effective length of query: 629
effective length of database: 14,082,258
effective search space: 8857740282
effective search space used: 8857740282
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.