Guide to the Human Genome
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Search of human proteins with 169646441

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169646441 GDP dissociation inhibitor 2 isoform 2 [Homo
sapiens]
         (400 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169646441 GDP dissociation inhibitor 2 isoform 2 [Homo sapiens]    811   0.0  
gi|6598323 GDP dissociation inhibitor 2 isoform 1 [Homo sapiens]      790   0.0  
gi|4503971 GDP dissociation inhibitor 1 [Homo sapiens]                699   0.0  
gi|53832014 choroideremia-like Rab escort protein 2 [Homo sapiens]     76   5e-14
gi|9966761 choroideremia isoform a [Homo sapiens]                      69   7e-12
gi|224028271 choroideremia isoform b [Homo sapiens]                    52   1e-06
gi|19923312 v-myc myelocytomatosis viral related oncogene, neuro...    32   1.3  
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]            31   2.3  
gi|105990541 ATP-binding cassette, sub-family A member 4 [Homo s...    30   3.9  
gi|68509940 Golli-mbp isoform 1 [Homo sapiens]                         30   3.9  
gi|68509928 myelin basic protein isoform 3 [Homo sapiens]              30   3.9  
gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]    30   5.0  
gi|4557880 interferon gamma receptor 1 precursor [Homo sapiens]        29   8.6  
gi|14251207 MOV10-like 1 [Homo sapiens]                                29   8.6  

>gi|169646441 GDP dissociation inhibitor 2 isoform 2 [Homo sapiens]
          Length = 400

 Score =  811 bits (2096), Expect = 0.0
 Identities = 400/400 (100%), Positives = 400/400 (100%)

Query: 1   MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG 60
           MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG
Sbjct: 1   MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG 60

Query: 61  SPPESMGRGRDWNVDLIPKFLMANGLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKK 120
           SPPESMGRGRDWNVDLIPKFLMANGLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKK
Sbjct: 61  SPPESMGRGRDWNVDLIPKFLMANGLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKK 120

Query: 121 TTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYL 180
           TTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYL
Sbjct: 121 TTMRDVYKKFDLGQDVIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYL 180

Query: 181 YPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPS 240
           YPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPS
Sbjct: 181 YPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPS 240

Query: 241 YVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAA 300
           YVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAA
Sbjct: 241 YVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAA 300

Query: 301 QGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYD 360
           QGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYD
Sbjct: 301 QGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYD 360

Query: 361 ATTHFETTCDDIKNIYKRMTGSEFDFEEMKRKKNDIYGED 400
           ATTHFETTCDDIKNIYKRMTGSEFDFEEMKRKKNDIYGED
Sbjct: 361 ATTHFETTCDDIKNIYKRMTGSEFDFEEMKRKKNDIYGED 400


>gi|6598323 GDP dissociation inhibitor 2 isoform 1 [Homo sapiens]
          Length = 445

 Score =  790 bits (2040), Expect = 0.0
 Identities = 400/445 (89%), Positives = 400/445 (89%), Gaps = 45/445 (10%)

Query: 1   MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG 60
           MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG
Sbjct: 1   MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG 60

Query: 61  SPPESMGRGRDWNVDLIPKFLMANG----------------------------------- 85
           SPPESMGRGRDWNVDLIPKFLMANG                                   
Sbjct: 61  SPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVTEGSFVYKGGKIYKVP 120

Query: 86  ----------LMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQD 135
                     LMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQD
Sbjct: 121 STEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQD 180

Query: 136 VIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR 195
           VIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR 240

Query: 196 LSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRV 255
           LSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRV
Sbjct: 241 LSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRV 300

Query: 256 ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETK 315
           ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETK
Sbjct: 301 ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETK 360

Query: 316 EPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNI 375
           EPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNI
Sbjct: 361 EPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNI 420

Query: 376 YKRMTGSEFDFEEMKRKKNDIYGED 400
           YKRMTGSEFDFEEMKRKKNDIYGED
Sbjct: 421 YKRMTGSEFDFEEMKRKKNDIYGED 445


>gi|4503971 GDP dissociation inhibitor 1 [Homo sapiens]
          Length = 447

 Score =  699 bits (1804), Expect = 0.0
 Identities = 342/444 (77%), Positives = 377/444 (84%), Gaps = 45/444 (10%)

Query: 1   MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASITPLEDLYKRFKIPG 60
           M+EEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGES+SITPLE+LYKRF++  
Sbjct: 1   MDEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESSSITPLEELYKRFQLLE 60

Query: 61  SPPESMGRGRDWNVDLIPKFLMANG----------------------------------- 85
            PPESMGRGRDWNVDLIPKFLMANG                                   
Sbjct: 61  GPPESMGRGRDWNVDLIPKFLMANGQLVKMLLYTEVTRYLDFKVVEGSFVYKGGKIYKVP 120

Query: 86  ----------LMGLFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQD 135
                     LMG+FEKRRFRKFLV+VANFDE DP+TFEG+DP+ T+MRDVY+KFDLGQD
Sbjct: 121 STETEALASNLMGMFEKRRFRKFLVFVANFDENDPKTFEGVDPQTTSMRDVYRKFDLGQD 180

Query: 136 VIDFTGHALALYRTDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR 195
           VIDFTGHALALYRTDDYLDQPC ET+NRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR
Sbjct: 181 VIDFTGHALALYRTDDYLDQPCLETVNRIKLYSESLARYGKSPYLYPLYGLGELPQGFAR 240

Query: 196 LSAIYGGTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRV 255
           LSAIYGGTYMLNKP+++II++NGKV+GVKSEGE+ARCKQLICDPSY+ DRV K GQVIR+
Sbjct: 241 LSAIYGGTYMLNKPVDDIIMENGKVVGVKSEGEVARCKQLICDPSYIPDRVRKAGQVIRI 300

Query: 256 ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETK 315
           ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMIS+AHNVAAQGKYIAI STTVET 
Sbjct: 301 ICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISYAHNVAAQGKYIAIASTTVETT 360

Query: 316 EPEKEIRPALELLEPIEQKFVSISDLLVPKDLGTESQIFISRTYDATTHFETTCDDIKNI 375
           +PEKE+ PALELLEPI+QKFV+ISDL  P D G ESQ+F S +YDATTHFETTC+DIK+I
Sbjct: 361 DPEKEVEPALELLEPIDQKFVAISDLYEPIDDGCESQVFCSCSYDATTHFETTCNDIKDI 420

Query: 376 YKRMTGSEFDFEEMKRKKNDIYGE 399
           YKRM G+ FDFE MKRK+ND++GE
Sbjct: 421 YKRMAGTAFDFENMKRKQNDVFGE 444


>gi|53832014 choroideremia-like Rab escort protein 2 [Homo sapiens]
          Length = 656

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 51/196 (26%), Positives = 96/196 (48%), Gaps = 13/196 (6%)

Query: 89  LFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYR 148
           + EKR   KFL +   + E+ P  ++    ++ +  +  K   L  ++  F  H++A+  
Sbjct: 291 MVEKRMLMKFLTFCLEY-EQHPDEYQAF--RQCSFSEYLKTKKLTPNLQHFVLHSIAMTS 347

Query: 149 TDDYLDQPCYETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNK 208
                     + +N  K + + L R+G +P+L+PLYG GE+PQGF R+ A++GG Y L  
Sbjct: 348 ESSCTT---IDGLNATKNFLQCLGRFGNTPFLFPLYGQGEIPQGFCRMCAVFGGIYCLRH 404

Query: 209 PIEEIIV--QNGKVIGVKSE-GEIARCKQLICDPSYVKDRV---EKVGQVIRVICILSHP 262
            ++  +V  ++G+   +    G+    K  I + SY+ +      +  Q+ R + I    
Sbjct: 405 KVQCFVVDKESGRCKAIIDHFGQRINAKYFIVEDSYLSEETCSNVQYKQISRAVLITDQS 464

Query: 263 IKNTN-DANSCQIIIP 277
           I  T+ D  +  +I+P
Sbjct: 465 ILKTDLDQQTSILIVP 480



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 22/44 (50%), Positives = 32/44 (72%)

Query: 4  EYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASIT 47
          E+DV+++GTGL E IL+   S +G++VLH+D   YYGG  AS +
Sbjct: 8  EFDVVIIGTGLPESILAAACSRSGQRVLHIDSRSYYGGNWASFS 51


>gi|9966761 choroideremia isoform a [Homo sapiens]
          Length = 653

 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 63/269 (23%), Positives = 119/269 (44%), Gaps = 29/269 (10%)

Query: 89  LFEKRRFRKFLVYVANFDEKDPRTFEGIDPKKTTMRDVYKKFDLGQDVIDFTGHALALYR 148
           + EKR   KFL +   + EK P  ++G +  + T  +  K   L  ++     H++A+  
Sbjct: 289 MVEKRMLMKFLTFCMEY-EKYPDEYKGYE--EITFYEYLKTQKLTPNLQYIVMHSIAM-- 343

Query: 149 TDDYLDQPCYETINRIKL---YSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYM 205
                 +    TI+ +K    +   L RYG +P+L+PLYG GELPQ F R+ A++GG Y 
Sbjct: 344 ----TSETASSTIDGLKATKNFLHCLGRYGNTPFLFPLYGQGELPQCFCRMCAVFGGIYC 399

Query: 206 LNKPIEEIIV----QNGKVIGVKSEGEIARCKQLICDPSYVKDRV---EKVGQVIRVICI 258
           L   ++ ++V    +  K I +   G+    +  + + SY  + +    +  Q+ R + I
Sbjct: 400 LRHSVQCLVVDKESRKCKAI-IDQFGQRIISEHFLVEDSYFPENMCSRVQYRQISRAVLI 458

Query: 259 LSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPE 318
               +  T+      I+    +      + V  +  +     +G Y+  ++ T       
Sbjct: 459 TDRSVLKTDSDQQISILTVPAEEPGTFAVRVIELCSSTMTCMKGTYLVHLTCT------- 511

Query: 319 KEIRPALELLEPIEQK-FVSISDLLVPKD 346
              + A E LE + QK FV  +++ +  +
Sbjct: 512 -SSKTAREDLESVVQKLFVPYTEMEIENE 539



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 23/44 (52%), Positives = 32/44 (72%)

Query: 4  EYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASIT 47
          E+DVIV+GTGL E I++   S +G++VLH+D   YYGG  AS +
Sbjct: 8  EFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFS 51


>gi|224028271 choroideremia isoform b [Homo sapiens]
          Length = 110

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 23/44 (52%), Positives = 32/44 (72%)

Query: 4  EYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGGESASIT 47
          E+DVIV+GTGL E I++   S +G++VLH+D   YYGG  AS +
Sbjct: 8  EFDVIVIGTGLPESIIAAACSRSGRRVLHVDSRSYYGGNWASFS 51


>gi|19923312 v-myc myelocytomatosis viral related oncogene,
          neuroblastoma derived [Homo sapiens]
          Length = 464

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 14/36 (38%), Positives = 22/36 (61%)

Query: 34 DRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRG 69
          D + +Y G   S  P ED++K+F++  +PP S  RG
Sbjct: 31 DEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRG 66


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 20/95 (21%), Positives = 44/95 (46%), Gaps = 12/95 (12%)

Query: 202 GTYMLNKPIEEIIVQNGKVIGVKSEGEIARCKQLICDPSYV---------KDRVEKVGQV 252
           G ++L  P   +  ++   +  K +   +R ++  C P+ +         +DR + +G+ 
Sbjct: 488 GLHLLKVPCSSLCAESSGAVETKLQAIFSRARR--CRPAVLLLTAVDLLGRDR-DGLGED 544

Query: 253 IRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDI 287
            RV+ +L H + N +  NSC  ++     +R  D+
Sbjct: 545 ARVMAVLRHLLLNEDPLNSCPPLMVVATTSRAQDL 579


>gi|105990541 ATP-binding cassette, sub-family A member 4 [Homo
            sapiens]
          Length = 2273

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 8/94 (8%)

Query: 18   ILSGIMSVNGKKVL--------HMDRNPYYGGESASITPLEDLYKRFKIPGSPPESMGRG 69
            + SG  +V GK +L        +M   P +      +T  E LY   ++ G P E + + 
Sbjct: 1991 VTSGDATVAGKSILTNISEVHQNMGYCPQFDAIDELLTGREHLYLYARLRGVPAEEIEKV 2050

Query: 70   RDWNVDLIPKFLMANGLMGLFEKRRFRKFLVYVA 103
             +W++  +   + A+ L G +     RK    +A
Sbjct: 2051 ANWSIKSLGLTVYADCLAGTYSGGNKRKLSTAIA 2084


>gi|68509940 Golli-mbp isoform 1 [Homo sapiens]
          Length = 304

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 7/52 (13%)

Query: 26  NGKKVLHMDRNPYYG-------GESASITPLEDLYKRFKIPGSPPESMGRGR 70
           +GK   H  R  +YG       G +    P+   +K    P +PP S G+GR
Sbjct: 190 SGKDSHHPARTAHYGSLPQKSHGRTQDENPVVHFFKNIVTPRTPPPSQGKGR 241


>gi|68509928 myelin basic protein isoform 3 [Homo sapiens]
          Length = 171

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 7/52 (13%)

Query: 26  NGKKVLHMDRNPYYG-------GESASITPLEDLYKRFKIPGSPPESMGRGR 70
           +GK   H  R  +YG       G +    P+   +K    P +PP S G+GR
Sbjct: 57  SGKDSHHPARTAHYGSLPQKSHGRTQDENPVVHFFKNIVTPRTPPPSQGKGR 108


>gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]
          Length = 610

 Score = 29.6 bits (65), Expect = 5.0
 Identities = 13/39 (33%), Positives = 25/39 (64%)

Query: 3   EEYDVIVLGTGLTECILSGIMSVNGKKVLHMDRNPYYGG 41
           E+ DV+V+G+G      + I++  GK+VL ++++   GG
Sbjct: 66  EKLDVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGG 104


>gi|4557880 interferon gamma receptor 1 precursor [Homo sapiens]
          Length = 489

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 13/31 (41%), Positives = 21/31 (67%), Gaps = 1/31 (3%)

Query: 366 ETTCD-DIKNIYKRMTGSEFDFEEMKRKKND 395
           ETTC   + N+Y RM GSE  ++ + +K++D
Sbjct: 164 ETTCYIRVYNVYVRMNGSEIQYKILTQKEDD 194


>gi|14251207 MOV10-like 1 [Homo sapiens]
          Length = 1211

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 8/77 (10%)

Query: 251  QVIRVICILSHPIKNTNDANSCQIIIP-QNQVN------RKSDIYVCMISFAHNVAAQGK 303
            QV+R  C+L+H I +   A+   +I P + QV       R  D+    +        Q +
Sbjct: 1042 QVLRYCCLLAHSISSQVSASDIGVITPYRKQVEKIRILLRNVDLMDIKVGSVEEFQGQ-E 1100

Query: 304  YIAIVSTTVETKEPEKE 320
            Y+ I+ +TV + E   E
Sbjct: 1101 YLVIIISTVRSNEDRFE 1117


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.139    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,934,886
Number of Sequences: 37866
Number of extensions: 664264
Number of successful extensions: 1338
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1323
Number of HSP's gapped (non-prelim): 21
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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