Guide to the Human Genome
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Search of human proteins with 169217576

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169217576 PREDICTED: similar to nebulin [Homo sapiens]
         (410 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169217576 PREDICTED: similar to nebulin [Homo sapiens]             837   0.0  
gi|115527120 nebulin [Homo sapiens]                                   503   e-142
gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]             357   1e-98
gi|46049092 nebulin-related anchoring protein isoform C [Homo sa...   330   1e-90
gi|46049105 nebulin-related anchoring protein isoform S [Homo sa...   330   1e-90
gi|5453758 nebulette sarcomeric isoform [Homo sapiens]                 91   1e-18
gi|47087157 nebulette non-muscle isoform [Homo sapiens]                50   4e-06
gi|5453710 LIM and SH3 protein 1 [Homo sapiens]                        47   4e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    32   1.0  
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    32   1.0  
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]      30   4.0  
gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]               30   5.2  
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa...    30   5.2  
gi|4885237 forkhead box C2 [Homo sapiens]                              29   8.8  

>gi|169217576 PREDICTED: similar to nebulin [Homo sapiens]
          Length = 410

 Score =  837 bits (2163), Expect = 0.0
 Identities = 410/410 (100%), Positives = 410/410 (100%)

Query: 1   MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
           MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL
Sbjct: 1   MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 61  GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
           GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV
Sbjct: 61  GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
           SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK
Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180

Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
           NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD
Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
           TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE
Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
           KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ
Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDVSVSPRKQVPHCFA 410
           ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDVSVSPRKQVPHCFA
Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDVSVSPRKQVPHCFA 410


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score =  503 bits (1295), Expect = e-142
 Identities = 238/396 (60%), Positives = 312/396 (78%)

Query: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
            ++ A +N +  S+KLY+    ++K++GYD+R DAI I+ AKASR+IAS+YKYKEGYRKQL
Sbjct: 3472 IMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQL 3531

Query: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
            GHH+G R ++DDPK +W+IH AKIQSDREYKK +EK K   ++P+DM+ +V AKKCQ+LV
Sbjct: 3532 GHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILV 3591

Query: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
            SDIDY++ LH+WTCLPDQNDVIQA+KAYDLQSD +YKSDLEWL+GIGW+P GSVEV +VK
Sbjct: 3592 SDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVK 3651

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A  +L++R YR   + LKFT I DTPE++ AK NA+ +S+ LY  AW+ +K +++V  D
Sbjct: 3652 RAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPD 3711

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
            TP +L +K N+  IS K Y + W++ KM  YDLRADAI I+ AKASRDIASDY YK AYE
Sbjct: 3712 TPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYE 3771

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            KQKGH+IG +S ++DPK++ A +  K+Q++R YKK +   K K S PVDM+SI  AK+ Q
Sbjct: 3772 KQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQ 3831

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
             L +D+DYR+YLH W+C PDQND+IQA+KAYDLQSD
Sbjct: 3832 TLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSD 3867



 Score =  501 bits (1291), Expect = e-142
 Identities = 240/396 (60%), Positives = 310/396 (78%), Gaps = 1/396 (0%)

Query: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
            +L A  N+  IS KLY K W+++K K YD+RADAI IK AKASR+IAS+YKYKE Y KQ 
Sbjct: 3715 ILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQK 3774

Query: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
            GHH+G ++++DDPK + AIHA KIQS+REYKK ++K K   ++P+DM+SI+ AKKCQ LV
Sbjct: 3775 GHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLV 3834

Query: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
            +DIDYRNYLH+WTC+PDQND+IQAKKAYDLQSD LYK+DLEWL+GIGW+P+GS EV+RVK
Sbjct: 3835 TDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVK 3894

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
            NAQN+  + +YR     LK+TSIVDTPEV+ AK NA  IS P YR  W+K+K ++++  D
Sbjct: 3895 NAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPD 3954

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
            TP +  ++ NAL +SNK Y++ W+++K  G D+R DAI IQ AKASR+IASDY YK  +E
Sbjct: 3955 TPEINLARANALNVSNKLYREGWDEMK-AGCDVRLDAIPIQAAKASREIASDYKYKLDHE 4013

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            KQKGHY+G  +A++D K+ WA    K+QN+R Y+  +   KAKI  PVDM+SI  +K  Q
Sbjct: 4014 KQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQ 4073

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
            AL SD+DYR+YLH W+C PDQNDVIQA+KAY+LQSD
Sbjct: 4074 ALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSD 4109



 Score =  494 bits (1272), Expect = e-140
 Identities = 232/396 (58%), Positives = 303/396 (76%)

Query: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
            ++ A  N +  S  LY++   + K++GYD+R+DAI I  AKASR+IAS+YKYKE YRKQL
Sbjct: 3229 IMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQL 3288

Query: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
            GHH+G R + DDPK +W++H AK+QSDREYKK +EK K  +++P+DM+ IV AKKCQ LV
Sbjct: 3289 GHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLV 3348

Query: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
            SD+DY++ LH+W CLPDQND+I A+KAYDLQSDNLYKSDLEW+KGIGW+P  S+EV+R K
Sbjct: 3349 SDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAK 3408

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A  LL++ +YR +PE LKFTSI DTPE + AK NA+ +++ LY  AW+ +K  ++V  D
Sbjct: 3409 RAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPD 3468

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
            TP ++ +K+N +  S+K Y+ A E+ K  GYDLR DAI IQ AKASRDIASDY YK  Y 
Sbjct: 3469 TPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYR 3528

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            KQ GH+IG R+ K+DPK++W+ +V K+Q+DR YKK +   K K S PVDM+ +  AK+ Q
Sbjct: 3529 KQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQ 3588

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
             L SD+DY+H LH W+C PDQNDVIQARKAYDLQSD
Sbjct: 3589 ILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSD 3624



 Score =  483 bits (1244), Expect = e-136
 Identities = 223/396 (56%), Positives = 301/396 (76%)

Query: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
            ++ A  N +  S  LY+    + K+KGYD+R+DAI I  AKASR++ S+YKYK+GYRKQL
Sbjct: 2986 IMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQL 3045

Query: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
            GHH+G R ++DDPK +W++H AKIQSDREYKK +EK K   ++P+DM+ +V AKKCQ LV
Sbjct: 3046 GHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 3105

Query: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
            SD+DY+NYLH+WTCLPDQNDVI A++AYDLQSDN+YKSDL+WL+GIGW+P GS++V++ K
Sbjct: 3106 SDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCK 3165

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A  +L++ +YR  P+ LKFTS+ D+ E + AK NA+ +++ LY  AW+K+K  V++  D
Sbjct: 3166 RAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPD 3225

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
            TP ++ ++ N +  S   Y+QA E+ K  GYDLR+DAI I  AKASRDIASDY YK AY 
Sbjct: 3226 TPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYR 3285

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            KQ GH+IG R+  +DPK++W+ ++ K+Q+DR YKK +  +K + S PVDM+ I  AK+ Q
Sbjct: 3286 KQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQ 3345

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
             L SDVDY+H LH W C PDQND+I ARKAYDLQSD
Sbjct: 3346 TLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSD 3381



 Score =  478 bits (1231), Expect = e-135
 Identities = 223/393 (56%), Positives = 298/393 (75%)

Query: 4    AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHH 63
            A  N +  S+KLY+  + + K+KGYD+  DAI IK AKASREIASEYKYKEG+RKQLGHH
Sbjct: 2503 AKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHH 2562

Query: 64   MGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDI 123
            +G R ++DDPK +W++H AKIQSDREYKK +EK K   ++P+DM+ +V AKKCQ LVSD+
Sbjct: 2563 IGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDV 2622

Query: 124  DYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183
            DY+NYLHQWTCLPDQ+DVI A++AYDLQSDNLYKSDL+WLKGIGW+  GS+E  + K A 
Sbjct: 2623 DYKNYLHQWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRAT 2682

Query: 184  NLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPL 243
             +L++ +YR  P+  KF+S++D+  ++ AK NA+ ++  LY  AW+K+K  V++  DTP 
Sbjct: 2683 QILSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPE 2742

Query: 244  MLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQK 303
            +L +K N +  S K Y+   E+ K  GYD+R DAI I+ AKASRDIAS++ YK  Y KQ 
Sbjct: 2743 VLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQL 2802

Query: 304  GHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALA 363
            GH+IG R+ ++DPK++W+ +V K+Q+DR YKK +   K K S PVDM+ +  AK+ Q L 
Sbjct: 2803 GHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 2862

Query: 364  SDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
            SDVDY++YLH W+C PDQ+DVI AR+AYDLQSD
Sbjct: 2863 SDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSD 2895



 Score =  478 bits (1230), Expect = e-135
 Identities = 222/396 (56%), Positives = 300/396 (75%)

Query: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
            +L A  N +  S KLY+    + K+KGYD+R DAI IK AKASR+IASE+KYKEGYRKQL
Sbjct: 2743 VLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQL 2802

Query: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
            GHH+G R ++DDPK +W++H AKIQSDREYKK +EK K   ++P+DM+ +V AKKCQ LV
Sbjct: 2803 GHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 2862

Query: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
            SD+DY+NYLHQWTCLPDQ+DVI A++AYDLQSDN+YKSDL+W++GIGW+  GS++V + K
Sbjct: 2863 SDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCK 2922

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A  +L++++YR  P+  KFTS+ D+ E + AK NA+ +++ LY  AW+K+K  +++  D
Sbjct: 2923 RATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPD 2982

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
            TP ++ ++ N +  S   Y+ A E+ K  GYDLR+DAI I  AKASRD+ SDY YK  Y 
Sbjct: 2983 TPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYR 3042

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            KQ GH+IG R+ ++DPK++W+ +V K+Q+DR YKK +   K K S PVDM+ +  AK+ Q
Sbjct: 3043 KQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQ 3102

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
             L SDVDY++YLH W+C PDQNDVI AR+AYDLQSD
Sbjct: 3103 TLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSD 3138



 Score =  477 bits (1227), Expect = e-135
 Identities = 223/396 (56%), Positives = 300/396 (75%)

Query: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
            +LQA  N    S KLY+  W +  +KGYD+  DAI ++ AKASR+IAS+YKYK+GYRKQL
Sbjct: 2257 ILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQL 2316

Query: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
            GHH+GFR+LQDDPK V +++ AK+QS+REYKK +EK K   ++P+DM+ +V AKKCQ LV
Sbjct: 2317 GHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELV 2376

Query: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
            SD+DY+NYLHQWTCLPDQNDV+QAKK Y+LQS+NLYKSDLEWL+GIGW P GS+E  + K
Sbjct: 2377 SDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNK 2436

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A  +++E+ YR  P+  KFTSI D  +++ AK NA   S+ LYR AW+K+K  +++  D
Sbjct: 2437 RASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPD 2496

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
            TP ++ +K N +  S+K Y+  +E++K  GYDL  DAI I+ AKASR+IAS+Y YK  + 
Sbjct: 2497 TPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFR 2556

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            KQ GH+IG R+ ++DPK++W+ +V K+Q+DR YKK +   K K S PVDM+ +  AK+ Q
Sbjct: 2557 KQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQ 2616

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
             L SDVDY++YLH W+C PDQ+DVI AR+AYDLQSD
Sbjct: 2617 TLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSD 2652



 Score =  420 bits (1079), Expect = e-117
 Identities = 206/393 (52%), Positives = 275/393 (69%), Gaps = 2/393 (0%)

Query: 4    AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHH 63
            A  NAL +SNKLY++ W++ K  G D+R DAI I+ AKASREIAS+YKYK  + KQ GH+
Sbjct: 3961 ARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHY 4019

Query: 64   MGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDI 123
            +G  T +DD K  WA+ A K+Q++REY+  + K K    +P+DM+SI+ +K  Q LVSD+
Sbjct: 4020 VGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDM 4079

Query: 124  DYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183
            DYRNYLHQWTC+PDQNDVIQAKKAY+LQSDN+YK+DLEWL+GIGW+P  SV V   K+A 
Sbjct: 4080 DYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAA 4139

Query: 184  NLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPL 243
            ++ +E+ YR K E L FT + D  + + AK +   + +  YR  W   K+   +  +TPL
Sbjct: 4140 DIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTL-TETPL 4198

Query: 244  MLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQK 303
            +  ++  A  +    Y++ WE  K TGY L  DA+   HA    D+ S+  YK  + KQK
Sbjct: 4199 LHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQK 4258

Query: 304  GHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALA 363
            GHY+G  + ++DPKLVW  +  ++QN+RLYK+ Y+  KAKI+IP DMVS+ AAK+GQ L 
Sbjct: 4259 GHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLV 4318

Query: 364  SDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
            SD+DYR+YLH W C PDQNDVIQARKAYDLQSD
Sbjct: 4319 SDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSD 4351



 Score =  392 bits (1006), Expect = e-109
 Identities = 192/397 (48%), Positives = 269/397 (67%), Gaps = 1/397 (0%)

Query: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
            ++ A  NA+ +S+KLY+    ++K+KGYD+R DAI IK AKASR+IAS+YKYK  Y K  
Sbjct: 2013 IILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGK 2072

Query: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
            G  +GFR+L+DDPK V ++  AK+QSDREYKK YE +K  ++TP DM+S+  AK  Q  +
Sbjct: 2073 GKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANI 2132

Query: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRV 179
            ++ +Y++ +H++  LPD  ++   +    +QSDN YK D  EW KG+GW P GS+EV + 
Sbjct: 2133 TNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKA 2192

Query: 180  KNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA 239
            K A    +++ YR  P   +F  + D+ +++ AK NA  +++ LY   W K+K  ++V  
Sbjct: 2193 KKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMP 2252

Query: 240  DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299
            DTP +LQ+K N    S K Y+  WE+    GYDL  DAI +Q AKASRDIASDY YK  Y
Sbjct: 2253 DTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGY 2312

Query: 300  EKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEG 359
             KQ GH++G RS ++DPKLV + NV KMQ++R YKK +   K K S PVDM+ +  AK+ 
Sbjct: 2313 RKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKC 2372

Query: 360  QALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
            Q L SDVDY++YLH W+C PDQNDV+QA+K Y+LQS+
Sbjct: 2373 QELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSE 2409



 Score =  380 bits (977), Expect = e-106
 Identities = 195/396 (49%), Positives = 262/396 (66%), Gaps = 1/396 (0%)

Query: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61
            +QA +NAL +S+  Y+ DW  T  KGYD+R DAI I  AK+SR IAS+ KYKE Y K  G
Sbjct: 1526 IQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKG 1585

Query: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121
              +GF +LQDDPK V  ++ AKIQSDREYKK YE SK  ++TPLDM+S+  AKK Q + +
Sbjct: 1586 KQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQEVAT 1645

Query: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRVK 180
            + +YR   H +T LPD  +V  ++ A  +QSDNLYKSD   W+KGIGW+P  S+EV + K
Sbjct: 1646 NANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKAK 1705

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A  +L+E+ YR  PE LKFT  +DT E    K N + + + LY   W K+K  ++V  D
Sbjct: 1706 KAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPD 1765

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
            TP +L S++N + +S+K Y+  WE+ K  GYDLR DAI I+ A+ASRDIASDY YK AYE
Sbjct: 1766 TPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYE 1825

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            + KG +IG RS ++DPKLV    V KMQ+DR YKK Y   K     PVDM+S+ AAK+ Q
Sbjct: 1826 QAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQ 1885

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
             +A++ +YR+ +H ++  PD      A+    +QSD
Sbjct: 1886 EVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSD 1921



 Score =  379 bits (972), Expect = e-105
 Identities = 195/396 (49%), Positives = 267/396 (67%), Gaps = 1/396 (0%)

Query: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61
            +QA +NA  IS  +Y+ D  D  +KGYD+R DAI I+ AKA+R+ AS+ +YK+ Y K  G
Sbjct: 1038 IQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKG 1097

Query: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121
              +GF++LQDDPK V  ++ AKIQSDREYKK YEK+K  +NTP DM ++V AKK Q +VS
Sbjct: 1098 KMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVS 1157

Query: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180
            +++Y++ LH +T LPD  D+  +K    +QSDN+YK D   W+KGIGW+P GS++V +VK
Sbjct: 1158 NVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVK 1217

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A + LNE+ YR  P+ LKFTSIVD+P ++QAK N  Q+S+ LY+   E  K    +  D
Sbjct: 1218 KAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPD 1277

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
             P  LQ+K NA  IS+  Y++ W D+   G ++  DAI I  AKASR+IASDY YK AYE
Sbjct: 1278 LPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYE 1337

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            K KG ++G RS ++DPKLV   NV K+Q+DR YKK Y + K     P DMVSI+AAK  Q
Sbjct: 1338 KSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQ 1397

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
             +A++V+Y+  LHH++  PD   +   R    +QSD
Sbjct: 1398 DVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSD 1433



 Score =  377 bits (967), Expect = e-104
 Identities = 186/397 (46%), Positives = 272/397 (68%), Gaps = 1/397 (0%)

Query: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
            +L + +N + +S+KLY+  W + K+KGYD+R DAI IK A+ASR+IAS+YKYK+ Y +  
Sbjct: 1769 ILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAK 1828

Query: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
            G H+GFR+L+DDPK V  +  AK+QSDREYKK YEKSK   +TP+DM+S+V AKK Q + 
Sbjct: 1829 GKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVA 1888

Query: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRV 179
            ++ +YRN +H +  LPD      AK    +QSDN YK+D  +++KGIGWLP GS+E  + 
Sbjct: 1889 TNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKN 1948

Query: 180  KNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA 239
            K A  +++E+ YR  P+ LK+++++D+  ++ A+ NA  ++E LY+ AWE +K  V++  
Sbjct: 1949 KKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP 2008

Query: 240  DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299
            D P ++ +K NA+ +S+K Y+ + E+ K  GYDLR DAI I+ AKASRDIASDY YK  Y
Sbjct: 2009 DIPQIILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNY 2068

Query: 300  EKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEG 359
            EK KG  +G RS ++DPKLV +  V KMQ+DR YKK Y + K     P DM+S++AAK+ 
Sbjct: 2069 EKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDA 2128

Query: 360  QALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
            QA  ++ +Y+H +H +   PD  ++   R    +QSD
Sbjct: 2129 QANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSD 2165



 Score =  362 bits (929), Expect = e-100
 Identities = 188/396 (47%), Positives = 260/396 (65%), Gaps = 1/396 (0%)

Query: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61
            LQA  NA  IS+  Y++DW+D   KG ++  DAI I  AKASR IAS+YKYKE Y K  G
Sbjct: 1282 LQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKG 1341

Query: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121
             H+GFR+LQDDPK V  ++ AK+QSDREYKK YE +K  ++TP DM+SI  AK  Q + +
Sbjct: 1342 KHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVAT 1401

Query: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180
            +++Y+  LH +T LPD   +   +    +QSDN+YK +   +LKGIGW+P GS+EV +VK
Sbjct: 1402 NVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVK 1461

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A + LNER YR  P+ +KFTS+ D+  ++ A+ N  Q+S+  Y+   EK K    +  +
Sbjct: 1462 KAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPE 1521

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
             P  +Q+K+NAL +S+  Y+  W+     GYDLR DAI I  AK+SR+IASD  YK AYE
Sbjct: 1522 LPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYE 1581

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            K KG  +G  S ++DPKLV   NV K+Q+DR YKK Y   K K   P+DMVS++AAK+ Q
Sbjct: 1582 KAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQ 1641

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
             +A++ +YR   HH++  PD  +V  +R A  +QSD
Sbjct: 1642 EVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSD 1677



 Score =  355 bits (912), Expect = 3e-98
 Identities = 180/396 (45%), Positives = 257/396 (64%), Gaps = 1/396 (0%)

Query: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61
            +Q  +NA  +S+ +Y++DW  +K K +DI+ DAI +  AKA+ +  S+  YK+ Y K  G
Sbjct: 794  IQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKG 853

Query: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121
              +G  ++ DDPK + ++  AK QSDREY+K YEKSK I+  PLDM+ + QAKK Q + S
Sbjct: 854  KMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIAS 913

Query: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180
            D+DY++ LH ++  PD  +V  AKKAY LQSD  YK+D   W+KG GW+P GS+E+ + K
Sbjct: 914  DVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAK 973

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A ++LNE+ YR  P+ LKFTSI D P  +Q+KIN  Q S+  Y+   E+     N+P D
Sbjct: 974  RASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPD 1033

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
             P  +Q+K+NA  IS   Y+   +D+   GYDLR DAI I+ AKA+R  ASD  YK  YE
Sbjct: 1034 LPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYE 1093

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            K KG  +G +S ++DPKLV   NV K+Q+DR YKK Y   K+K + P DM ++ AAK+ Q
Sbjct: 1094 KAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQ 1153

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
             + S+V+Y+H LHH++  PD  D+  ++    +QSD
Sbjct: 1154 DVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSD 1189



 Score =  332 bits (850), Expect = 5e-91
 Identities = 174/386 (45%), Positives = 239/386 (61%), Gaps = 6/386 (1%)

Query: 15   LYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPK 74
            LY++ W   K  GY +  DA+   HA    ++ SE KYK  + KQ GH++G  T++DDPK
Sbjct: 4213 LYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPK 4272

Query: 75   SVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTC 134
             VW  HA +IQ++R YK+ Y K+K   N P DM+S++ AK+ Q LVSDIDYRNYLHQW C
Sbjct: 4273 LVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMC 4332

Query: 135  LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIK 194
             PDQNDVIQA+KAYDLQSDN+Y++DLEWL+GIGW+P  SV+ +RV   Q ++++  Y  K
Sbjct: 4333 HPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKNQEMMSQIKY--K 4390

Query: 195  PEALK----FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKIN 250
              AL+    F S+VD PE++ AKIN+V  S+  Y+  + K K       DTP +  SK  
Sbjct: 4391 KNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDM 4450

Query: 251  ALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCR 310
                S   Y+ AWE  K  GY L    I I  AK +  + S+  YK  YEKQKGHY+  +
Sbjct: 4451 GKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGK 4510

Query: 311  SAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYRH 370
               E P +V   +  KM++   Y+K Y D KA + IP DM++   AK  Q + SD++YRH
Sbjct: 4511 VIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRH 4570

Query: 371  YLHHWSCFPDQNDVIQARKAYDLQSD 396
            Y H W+   ++ +VI+ R A ++ SD
Sbjct: 4571 YFHQWTSLLEEPNVIRVRNAQEILSD 4596



 Score =  261 bits (668), Expect = 6e-70
 Identities = 142/400 (35%), Positives = 222/400 (55%), Gaps = 4/400 (1%)

Query: 2   LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61
           +Q  +NA  +S+ LY++DW  +K K +DI+ DAI +  AKA+ +  S+  YK+ Y K  G
Sbjct: 547 IQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKG 606

Query: 62  HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTPLDMMSIVQAKKCQ 117
             +G  ++ DDPK + ++  AK QSDR YK+ YEK+K        TP   +        +
Sbjct: 607 KMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSE 666

Query: 118 VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVM 177
               D+  ++ L  +    +        K     SD  YK++ E  KG  + P+   +  
Sbjct: 667 ARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEY 726

Query: 178 RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNV 237
                 +   +  Y++ P+  KFT++ D+P ++QA++N  Q+S+  Y+   E EK   ++
Sbjct: 727 EAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHI 786

Query: 238 PADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKT 297
           PAD P  +Q ++NA  +S+  Y+Q WE  K   +D++ DAI +  AKA+    SD +YK 
Sbjct: 787 PADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKK 846

Query: 298 AYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAK 357
            YEK KG  IG  S  +DPK++ +    K Q+DR Y+K Y   K   + P+DM+ ++ AK
Sbjct: 847 DYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAK 906

Query: 358 EGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397
           + QA+ASDVDY+H LH +S  PD  +V  A+KAY LQSDV
Sbjct: 907 KSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDV 946



 Score =  241 bits (615), Expect = 9e-64
 Identities = 136/388 (35%), Positives = 205/388 (52%), Gaps = 2/388 (0%)

Query: 12   SNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQD 71
            S  LY+  W  TK  GY +    I I  AK +  + SE KYKE Y KQ GH++  + + +
Sbjct: 4455 STILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGE 4514

Query: 72   DPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ 131
             P  V  +   K++S   Y+K YE +K   + P DMM+ V AK+CQ ++SD++YR+Y HQ
Sbjct: 4515 FPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQ 4574

Query: 132  WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLY 191
            WT L ++ +VI+ + A ++ SDN+YK DL WLKGIG     + +++  K + +L ++  Y
Sbjct: 4575 WTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQY 4634

Query: 192  RI--KPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKI 249
                K     +  + DTP  + A  + +  SE  Y+  + + K       +T    +++ 
Sbjct: 4635 TAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRN 4694

Query: 250  NALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGC 309
                 S+  Y++AW+ VK T Y L +  + + HAK  + +AS   Y+  YEK K  Y   
Sbjct: 4695 LKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLP 4754

Query: 310  RSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYR 369
            RS  +DP       V K+  DRLY+  Y  +K KI I  DMV +  AK+ Q   S++DYR
Sbjct: 4755 RSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYR 4814

Query: 370  HYLHHWSCFPDQNDVIQARKAYDLQSDV 397
              LH W C PD       RK  D  SD+
Sbjct: 4815 LRLHEWICHPDLQVNDHVRKVTDQISDI 4842



 Score =  182 bits (461), Expect = 6e-46
 Identities = 124/403 (30%), Positives = 190/403 (47%), Gaps = 14/403 (3%)

Query: 12   SNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQD 71
            S+ LY++ W+  K   Y + +  + + HAK  + +AS  KY+E Y K    +   R++ D
Sbjct: 4700 SSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDD 4759

Query: 72   DPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH 130
            DP +   +   K+  DR Y+  YEK+K  IH  P DM+ +V AK  Q  VS+IDYR  LH
Sbjct: 4760 DPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVP-DMVEMVTAKDSQKKVSEIDYRLRLH 4818

Query: 131  QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERL 190
            +W C PD       +K  D  SD +YK DL WLKGIG     + E++  K+A +L ++  
Sbjct: 4819 EWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIK 4878

Query: 191  YRIKPEALK----FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQ 246
            Y  K   LK    +  + DTP  +QA  +  Q+S+ +Y   +         P    + L 
Sbjct: 4879 Y--KAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLD 4936

Query: 247  SKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHY 306
              ++A ++ +    +       TGY L  D    +H K +R ++S + YK AYE  K + 
Sbjct: 4937 RALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAY- 4995

Query: 307  IGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDV 366
             G     +D   V    V  + ++RLY++ Y+  K KI    D   I   K+ Q   S++
Sbjct: 4996 -GYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSEL 5054

Query: 367  DYRHYLH----HWSCFPDQNDVIQARKAYDLQSDVSVSPRKQV 405
             Y+        H    P    VI  R   D+ SD+      QV
Sbjct: 5055 IYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQV 5097



 Score =  177 bits (448), Expect = 2e-44
 Identities = 110/346 (31%), Positives = 175/346 (50%), Gaps = 6/346 (1%)

Query: 4   AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH- 62
           A +NA  IS + YQ+D+ + K + Y ++ +  E K  K +   AS+ KYKE Y K  G  
Sbjct: 300 ARMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKA 359

Query: 63  HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTP-LDMMSIVQAKKCQ 117
                   ++P+      A    SD+ YK+ YEK+K        TP   + +++Q     
Sbjct: 360 DYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSD 419

Query: 118 VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVM 177
               D   ++ L  +    +        K     SD  YK++ E  +G G+ P+   +  
Sbjct: 420 KKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEY 479

Query: 178 RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNV 237
                 +   +  Y++ P+  KFT + D+P ++QA++N+ Q+S+  Y+   E EK   ++
Sbjct: 480 EAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHI 539

Query: 238 PADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKT 297
           P DTP  +Q K+NA  +S+  Y+Q WE  K   +D++ DAI +  AKA+    SD +YK 
Sbjct: 540 PPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKK 599

Query: 298 AYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAK 343
            YEK KG  IG  S  +DPK++ +  V K Q+DRLYK+ Y   KAK
Sbjct: 600 DYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAK 645



 Score =  133 bits (335), Expect = 3e-31
 Identities = 119/409 (29%), Positives = 183/409 (44%), Gaps = 30/409 (7%)

Query: 5    HINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYR--KQLGH 62
            H   LQ SN LY+     T   GY +  D    KH K +R ++S +KYKE Y   K  G+
Sbjct: 4940 HAYKLQSSN-LYKTSLR-TLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGY 4997

Query: 63   HMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKG-IHNTPLDMMSIVQAKKCQV 118
             +G       PK V  +H  ++    S+R Y++ Y K K  IH TP D   I Q KK Q 
Sbjct: 4998 TLG-------PKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTP-DTPEIRQVKKTQE 5049

Query: 119  LVSDIDYRNYLHQWT----CLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSV 174
             VS++ Y++   +       LP    VI  +   D+ SD  YK DL+ LKG G     + 
Sbjct: 5050 AVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTP 5109

Query: 175  EVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEK 232
            +++R ++ + L +  LY  K   +  K+  ++DTPE  + +     +SE +YR A +K+K
Sbjct: 5110 DMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQK 5169

Query: 233  ANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASD 292
            +      DTP +L++K      S   Y +     +   +        ++HAK  +D+ S+
Sbjct: 5170 SIFTSVPDTPDLLRAKRGQKLQSQYLYVEL-ATKERPHHHAGNQTTALKHAKDVKDMVSE 5228

Query: 293  YLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVS 352
              YK  YEK K  Y       + P L+ A       +D  YK+ +   K K     D + 
Sbjct: 5229 KKYKIQYEKMKDKY---TPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALD 5285

Query: 353  ISAAKEGQALASDVDYRH----YLHHWSCFPDQNDVIQARKAYDLQSDV 397
            I   ++     S + Y+      L  W   PD+ +    R   D  SDV
Sbjct: 5286 IVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDV 5334



 Score =  126 bits (317), Expect = 3e-29
 Identities = 111/401 (27%), Positives = 162/401 (40%), Gaps = 78/401 (19%)

Query: 37   IKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 96
            +KHAK  +++ SE KYK  Y K       +  + D P  + A  A    SD  YK+ ++K
Sbjct: 5216 LKHAKDVKDMVSEKKYKIQYEKMKDK---YTPVPDTPILIRAKRAYWNASDLRYKETFQK 5272

Query: 97   SKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYLHQ---WTCLPDQNDVIQAKKAYDLQS 152
            +KG ++T  D + IV  +K    +S I Y+ NY+ Q   W  +PD+ +    +   D  S
Sbjct: 5273 TKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVS 5332

Query: 153  DNLYKSDLEWLKGIGWLPEGSVEVM----------------------------------- 177
            D  YK DL WLKGIG     + +                                     
Sbjct: 5333 DVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINR 5392

Query: 178  RVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANV 235
              K A  L+NE+ YR   E  K  +  +VD P  + AK    QIS+  YR  +EK K   
Sbjct: 5393 HFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKF 5452

Query: 236  NVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLY 295
                DTP  L++     QIS+  Y+  +   K  GY    D   + H +  +D  SD  Y
Sbjct: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKY 5512

Query: 296  KTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISA 355
            K  Y++ K +   C    +   +  A +  K+  +  YKK Y  +KA             
Sbjct: 5513 KEVYQRNKSN---CTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKA------------- 5556

Query: 356  AKEGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
                              HW   PD+ D +QA K+   QSD
Sbjct: 5557 ------------------HWKWTPDRPDFLQAAKSSLQQSD 5579



 Score =  101 bits (252), Expect = 1e-21
 Identities = 102/381 (26%), Positives = 175/381 (45%), Gaps = 30/381 (7%)

Query: 6    INALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHM- 64
            +N  Q+++    K   +  +  Y    D +E  H K + E+ S  KYKE Y K+ G  M 
Sbjct: 5856 LNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPML 5915

Query: 65   GFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKS-KGIHNTPLDMM-SIVQAKKCQVLVSD 122
             F T    P  + A  + ++QS +EY+K YE+S KG + T L++  +++  K    + S+
Sbjct: 5916 DFET----PTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASE 5971

Query: 123  IDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWL---KGIGWLPEGS 173
             +YR  L +       T + D  D+++AK A  + ++  YK DLE     +G+  +   +
Sbjct: 5972 KEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANET 6031

Query: 174  VEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKE 231
             + MR +NA ++ ++  Y+   E  K  FTS+VDTPE+I A+      S+  Y+   EK 
Sbjct: 6032 PDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKS 6091

Query: 232  KANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIAS 291
             +      DTP + + + N    S  +YQ   ++ K     +  D   I   K ++   S
Sbjct: 6092 MSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSK-GKITVVQDTPEILRVKENQKNFS 6150

Query: 292  DYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMV 351
              LYK   +   G  IG     + P+++     +K   D +    Y +   + +   D+ 
Sbjct: 6151 SVLYKE--DVSPGTAIG-----KTPEMM----RVKQTQDHISSVKYKEAIGQGTPIPDLP 6199

Query: 352  SISAAKEGQALASDVDYRHYL 372
             +   KE Q   S V Y+  L
Sbjct: 6200 EVKRVKETQKHISSVMYKENL 6220



 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 91/376 (24%), Positives = 173/376 (46%), Gaps = 28/376 (7%)

Query: 10   QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69
            QIS+ LY+ ++N  K +GY    D   + H +  ++  S+ KYKE Y++   +     T+
Sbjct: 5470 QISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSN----CTI 5525

Query: 70   QDDPKSVWAI-HAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY--- 125
            + D   + A   A K+ ++ +YKK YE +K       D    +QA K  +  SD +Y   
Sbjct: 5526 EPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLD 5585

Query: 126  RNYLH--QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183
            R +L   + +   D+N V+  +    ++SD  YK      +G       + +++  K   
Sbjct: 5586 REFLKGCKLSVTDDKNTVLALRNTL-IESDLKYKEKHVKERGTCHAVPDTPQILLAKTVS 5644

Query: 184  NLLNERLYR--IKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAW--EKEKANVNV 237
            NL++E  Y+  +K    +  +T++ +T + +  K     +S+  Y+  +  EK K+N ++
Sbjct: 5645 NLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSI 5704

Query: 238  PADTPLMLQSKINALQISNKRYQQAW-EDVKMT-GYDLRADAIGIQHAKASRDIASDYLY 295
              + P +     +A++++ K+   A+ +D K    Y   AD   I+ A  +   AS+  Y
Sbjct: 5705 MLEPPEVK----HAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEY 5760

Query: 296  KTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKIS--IPVDMVSI 353
            +  + K+  H +   S    P +  A    K+ +   Y++ ++  K K     P D    
Sbjct: 5761 RAKHRKEGSHGL---SMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLY 5817

Query: 354  SAAKEGQALASDVDYR 369
               K+   LAS+V Y+
Sbjct: 5818 KVMKDANNLASEVKYK 5833



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 84/315 (26%), Positives = 143/315 (45%), Gaps = 11/315 (3%)

Query: 37  IKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ-SDREYKKAYE 95
           I H++  +++ S  KYKE + K  G      T   D   +  I   + Q S+ +Y+   +
Sbjct: 86  IAHSQKMQDLFSPNKYKEKFEKTKGQPYASTT---DTPELRRIKKVQDQLSEVKYRMDGD 142

Query: 96  KSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQ 151
            +K I +       I  AKK    VS + Y+        ++   PD  +++QA K   + 
Sbjct: 143 VAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMF 202

Query: 152 SDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEV 209
           S  LY  D E  K + +    S E+ RV  AQ  L++  Y+  +  +  +FT + D P++
Sbjct: 203 SKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDI 262

Query: 210 IQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMT 269
             AK    Q+S+  Y+  +E +            +  +++NA  IS ++YQ+ +E++K  
Sbjct: 263 EFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQ 322

Query: 270 GYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHY-IGCRSAKEDPKLVWAANVLKMQ 328
            Y ++ +    +  K +   AS   YK  YEK KG        A E+P+L          
Sbjct: 323 IYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDAL 382

Query: 329 NDRLYKKAYNDHKAK 343
           +D+LYK+ Y   KAK
Sbjct: 383 SDKLYKENYEKTKAK 397



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 105/408 (25%), Positives = 171/408 (41%), Gaps = 29/408 (7%)

Query: 8    ALQISN-KLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGF 66
            A Q+ N K Y+ D+   K K Y +  D      AK + +  S+ KY++ Y K       F
Sbjct: 5397 ATQLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK---F 5452

Query: 67   RTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-----GIHNTPLDMMSIVQAKKCQVLVS 121
             ++ D P+ +      K  SD  YK  Y K+K      IH+TP+    ++  +K +  VS
Sbjct: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPM----LLHVRKVKDEVS 5508

Query: 122  DIDYRNYLHQ----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-IGWLPEGSVEV 176
            D+ Y+    +     T  PD   +  AK AY + ++  YK   E  K    W P+   + 
Sbjct: 5509 DLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPD-RPDF 5567

Query: 177  MRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKAN 234
            ++   +    ++  Y++  E LK    S+ D    + A  N +  S+  Y+    KE+  
Sbjct: 5568 LQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGT 5627

Query: 235  VNVPADTPLMLQSK-INALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDY 293
             +   DTP +L +K ++ L   NK      + +    Y    +     H K      SD 
Sbjct: 5628 CHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT 5687

Query: 294  LYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSI 353
             YK  + K+KG         E P++  A  V K Q+D  Y+K   ++    ++  D   I
Sbjct: 5688 NYKKKFVKEKGK-SNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTV-ADRPDI 5745

Query: 354  SAAKEGQALASDVDYRHYLH----HWSCFPDQNDVIQARKAYDLQSDV 397
              A +    AS+V+YR        H      + D+  A+KA  L S V
Sbjct: 5746 KKATQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQV 5793



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 95/415 (22%), Positives = 167/415 (40%), Gaps = 55/415 (13%)

Query: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61
            ++A  +A +++  L  K   +  +  +    D  +   A  S    S+++YK       G
Sbjct: 5532 IKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKG 5591

Query: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121
              +   ++ DD  +V A+    I+SD +YK+ + K +G  +   D   I+ AK    LVS
Sbjct: 5592 CKL---SVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVS 5648

Query: 122  DIDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-----IGWLP 170
            +  Y++++ +      +T LP+  D +  K+     SD  YK      KG     I   P
Sbjct: 5649 ENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEP 5708

Query: 171  EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEK 230
                  M V   Q+ +  R  +   E L +T++ D P++ +A   A Q SE  YR    K
Sbjct: 5709 PEVKHAMEVAKKQSDVAYR--KDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRK 5766

Query: 231  EKANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTG----------YDLRADAIGI 280
            E ++       P +  +K  A   S  +Y++ ++  K             Y +  DA  +
Sbjct: 5767 EGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNL 5826

Query: 281  --------------------------QHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKE 314
                                       H   +  +AS Y YK  YEK KGHY    +  +
Sbjct: 5827 ASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHY---HTIPD 5883

Query: 315  DPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYR 369
            + + +      ++Q+   YK+ Y   + K  +  +  +   AKE Q + S  +YR
Sbjct: 5884 NLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYR 5938



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 91/349 (26%), Positives = 140/349 (40%), Gaps = 53/349 (15%)

Query: 10  QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYR--KQLGHHMGFR 67
           Q+S  LY+++W DTK K Y +  DA E+  A  +  + S+  Y E +   K L     F 
Sbjct: 166 QVSKVLYKQNWEDTKDK-YLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSL-----FY 219

Query: 68  TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN 127
              D P+      A K  SD  YKK   + +                             
Sbjct: 220 PYNDSPELRRVAQAQKALSDVAYKKGLAEQQA---------------------------- 251

Query: 128 YLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVKNAQNLL 186
              Q+T L D  D+  AKK  +  S   YK D E  +KG  W      EV   +   + +
Sbjct: 252 ---QFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKG-KWSETPCFEVANARMNADNI 307

Query: 187 NERLYRIKPEALK---FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKA----NVNVPA 239
           + R Y+   E +K   +    +TPE    K   V  S+  Y+  +EK K     NV   +
Sbjct: 308 STRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPAS 367

Query: 240 DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299
           + P + Q K     +S+K Y++ +E  K    +   +    +     ++ +SD  YK +Y
Sbjct: 368 ENPQLRQLKAAGDALSDKLYKENYEKTKAKSINY-CETPKFKLDTVLQNFSSDKKYKDSY 426

Query: 300 EKQ-KGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIP 347
            K   GHY+G   + EDP       V    +D+ YK  Y + + K   P
Sbjct: 427 LKDILGHYVG---SFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFP 472



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 100/419 (23%), Positives = 165/419 (39%), Gaps = 62/419 (14%)

Query: 1   MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
           ++QA  N    S KLY +DW   K   Y    D+ E++    +++  S+  YK+G  +Q 
Sbjct: 192 LVQAVKNTAMFSKKLYTEDWEADKSLFYPYN-DSPELRRVAQAQKALSDVAYKKGLAEQQ 250

Query: 61  GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYE-KSKG-IHNTPLDMMSIVQAKKCQV 118
                F  L D P   +A       S ++YK+ YE K KG    TP       +    ++
Sbjct: 251 AQ---FTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETP-----CFEVANARM 302

Query: 119 LVSDIDYRNYLHQWTCLPDQNDVIQA--------KKAYDLQSDNLYKSDLEWLKG---IG 167
              +I  R Y   +  + DQ   +Q         KKA    S   YK D E  KG     
Sbjct: 303 NADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYN 362

Query: 168 WLPEG-SVEVMRVKNAQNLLNERLYRIKPEALKFTSI--VDTPEVIQAKINAVQISEPLY 224
            LP   + ++ ++K A + L+++LY+   E  K  SI   +TP+     +     S+  Y
Sbjct: 363 VLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKY 422

Query: 225 RNAWEKEKANVNVPA-DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLR--------- 274
           ++++ K+     V + + P          Q S+K Y+  +E+ +  G+  +         
Sbjct: 423 KDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAI 482

Query: 275 -----------------------ADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRS 311
                                   D+  +  A+ +    SD  YK  +E +K     C  
Sbjct: 483 KKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEK---FKCHI 539

Query: 312 AKEDPKLVWAANVLKMQNDRLYKKAYNDHKA-KISIPVDMVSISAAKEGQALASDVDYR 369
             + P  +         +D LYK+ +   KA K  I VD + + AAK      SDV Y+
Sbjct: 540 PPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYK 598



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 52/226 (23%), Positives = 91/226 (40%), Gaps = 14/226 (6%)

Query: 36   EIKHAKASREIASEYKYKEGYRKQLGHHMGFRT-LQDDPKSVWAIHAAKIQSDREYKKAY 94
            E++  K ++E  S   YKE        +MG  T L   P+     H  +  S   YK+  
Sbjct: 6262 EMERVKRNQENFSSVLYKE--------NMGKGTPLAVTPEMERVKHNQENISSVLYKENV 6313

Query: 95   EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDN 154
             K+     TP     + + K+ Q  +S + Y+  L + T  P   ++ + K+  +  S  
Sbjct: 6314 GKATATPVTP----EMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVKRNQENFSSV 6369

Query: 155  LYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKI 214
            LYK ++         PE        +N  ++L    +R + +  K   ++DTPE+ + + 
Sbjct: 6370 LYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQG-KAAYVLDTPEMRRVRE 6428

Query: 215  NAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQ 260
                IS   Y   +EK K         P+  + K N    S+  Y+
Sbjct: 6429 TQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYR 6474



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 37/162 (22%), Positives = 64/162 (39%), Gaps = 10/162 (6%)

Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
           TP +  S+      S  +Y++ +E  K   Y    D   ++  K  +D  S+  Y+   +
Sbjct: 83  TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGD 142

Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
             K     C   ++   +  A  V +  +  LYK+ + D K K  +P D   +  A +  
Sbjct: 143 VAKTI---CHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNT 199

Query: 361 ALASDVDYRHYLHHW----SCFPDQNDVIQARKAYDLQSDVS 398
           A+ S    + Y   W    S F   ND  + R+    Q  +S
Sbjct: 200 AMFSK---KLYTEDWEADKSLFYPYNDSPELRRVAQAQKALS 238


>gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]
          Length = 237

 Score =  357 bits (915), Expect = 1e-98
 Identities = 177/188 (94%), Positives = 178/188 (94%), Gaps = 6/188 (3%)

Query: 50  YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 109
           YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS
Sbjct: 23  YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 110 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 169
           IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL
Sbjct: 83  IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142

Query: 170 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWE 229
           PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE       E
Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV------E 196

Query: 230 KEKANVNV 237
           K + N NV
Sbjct: 197 KSRDNFNV 204



 Score =  136 bits (342), Expect = 4e-32
 Identities = 62/104 (59%), Positives = 78/104 (75%)

Query: 293 YLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVS 352
           Y YK  Y KQ GH++G R+ ++DPK VWA +  K+Q+DR YKKAY   K   + P+DM+S
Sbjct: 23  YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 353 ISAAKEGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
           I  AK+ Q L SD+DYR+YLH W+C PDQNDVIQA+KAYDLQSD
Sbjct: 83  IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSD 126



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 15/194 (7%)

Query: 200 FTSIVDTPEVIQAKINAVQI-SEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKR 258
           F ++ D P+ + A I+A +I S+  Y+ A+EK K   N P D   ++Q+K   + +S+  
Sbjct: 39  FRTLQDDPKSVWA-IHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDID 97

Query: 259 YQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKEDPKL 318
           Y+       +  +    D   +  AK + D+ SD LYK+  E  KG  IG    +   ++
Sbjct: 98  YRN-----YLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGW-LPEGSVEV 149

Query: 319 VWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDY---RHYLHHW 375
           +   N   + N+RLY+        K +  VD   +  AK      S+V+       + H+
Sbjct: 150 MRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHY 207

Query: 376 SCFPDQNDVIQARK 389
             + DQ  +  A++
Sbjct: 208 GSYLDQKQLGPAQQ 221



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 46/162 (28%), Positives = 75/162 (46%), Gaps = 11/162 (6%)

Query: 135 LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIK 194
           L D    + A  A  +QSD  YK   E  KGI   P   + +++ K  Q L+++  YR  
Sbjct: 42  LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY 101

Query: 195 PEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQI 254
               ++T + D  +VIQAK      S+ LY++  E  K    +P  +  +++ K NA  +
Sbjct: 102 LH--QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK-NAQNL 158

Query: 255 SNKR-YQQAWEDVKMTG-------YDLRADAIGIQHAKASRD 288
            N+R Y+   E +K T           + +A+ I   + SRD
Sbjct: 159 LNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200


>gi|46049092 nebulin-related anchoring protein isoform C [Homo
            sapiens]
          Length = 1695

 Score =  330 bits (846), Expect = 1e-90
 Identities = 167/395 (42%), Positives = 250/395 (63%)

Query: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61
            LQA  NA  +S KLY+  W + K KG+++R D++    AKA R++ASE KYKE Y +  G
Sbjct: 737  LQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRG 796

Query: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121
              +G + +Q D +   ++  +K+QS+ EYKK +E +K   +  LDM+ +V A+K Q L +
Sbjct: 797  KLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLAT 856

Query: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181
            D+ Y+   H +T LP    V  AKKAY LQSDN Y++D++W+KG+GW+  GS+ V + K 
Sbjct: 857  DVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKK 916

Query: 182  AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241
            A  L++E+ YR  P+ALKFTSI DTPE++QA+I+  Q  + LYR   E  K +    AD 
Sbjct: 917  AGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADL 976

Query: 242  PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301
            P +L +K+NA+ IS  RY+++W  ++  GY LR DA+  Q AKAS +I SDY YK A+EK
Sbjct: 977  PEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEK 1036

Query: 302  QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361
             KG  +G RS ++D  L  +     +Q+D  YKK +   KA+  +P+DM ++  AK+ Q 
Sbjct: 1037 MKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQT 1096

Query: 362  LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
            LAS+ DY+H L  ++   +   +  A+KA+ LQS+
Sbjct: 1097 LASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSE 1131



 Score =  300 bits (767), Expect = 2e-81
 Identities = 157/396 (39%), Positives = 241/396 (60%), Gaps = 4/396 (1%)

Query: 1   MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
           +++A  NA   S   Y++ W  TK KG++++ DA+ +  AKAS E+AS  KYKE Y K  
Sbjct: 497 LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 556

Query: 61  GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
           G  MG      D + + ++  AK+ S+ EYKK +E+SK   + P+DM++I  AKK Q L 
Sbjct: 557 GKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 612

Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
           SD+DYR  LH++T LP+      AKKAY LQS+  YK+DL W+KG+GWL EGS+ + + K
Sbjct: 613 SDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAK 672

Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
            A  L++E+ YR + + LKFTS+ D+ ++  AK +    S   Y+   E+      +  D
Sbjct: 673 KAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 732

Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
            PL LQ++ NA  +S K Y+ +WE+ K  G++LR D++    AKA RD+AS+  YK  YE
Sbjct: 733 EPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYE 792

Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
           + +G  IG +  + D ++  +  + K+Q++  YKK + D K++  + +DMV +  A++ Q
Sbjct: 793 RSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQ 852

Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
            LA+DV Y+   HH++  P    V  A+KAY LQSD
Sbjct: 853 HLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSD 888



 Score =  298 bits (764), Expect = 5e-81
 Identities = 150/397 (37%), Positives = 247/397 (62%)

Query: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
            +L A +NA+ IS   Y++ W+  +  GY +R DA+  + AKAS EI S+YKYKE + K  
Sbjct: 979  VLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK 1038

Query: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
            G  +G R+L+DD     +++A  +QSD  YKK +E SK   + PLDM ++V AKK Q L 
Sbjct: 1039 GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLA 1098

Query: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
            S+ DY++ L Q+T L +   +  AKKA+ LQS+NLY+SDL +++G+  +  G++E+   K
Sbjct: 1099 SNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRK 1158

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A  L++E  YR  P + K+T++ DTP ++ AK +    +E LY+ A E  +    +   
Sbjct: 1159 KASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLG 1218

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
             P  +++K NA  +S+ RY+++W +++  GY L  +A+  Q A+AS DIASD+LY+  + 
Sbjct: 1219 LPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFV 1278

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            K++G  IG +S ++DP++     + ++Q++  Y++     +A+  +P+DMV +  AK  Q
Sbjct: 1279 KERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQ 1338

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397
            ALASD DYR   H ++  P+   +  A+KA+ LQS++
Sbjct: 1339 ALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSEL 1375



 Score =  283 bits (724), Expect = 2e-76
 Identities = 146/396 (36%), Positives = 241/396 (60%)

Query: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61
            ++A  NA  +S+  Y++ W + + +GY +  +A+  + A+AS +IAS++ Y+  + K+ G
Sbjct: 1223 IRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERG 1282

Query: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121
              +G ++++DDP+        ++QS+ +Y++    S+   + P+DM+ +V AK  Q L S
Sbjct: 1283 KLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALAS 1342

Query: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181
            D DYR   H++T LP+   +  AKKA+ LQS+  YKSDL  +KGIGWL   S ++   K 
Sbjct: 1343 DHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKK 1402

Query: 182  AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241
            A  L++E  YR KP+++KFT++VD+P+++ AK + +  +E +YR+   +      +  D 
Sbjct: 1403 AGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDH 1462

Query: 242  PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301
            P   ++++NAL +S+K Y+ +WE  +   YD R DAI  Q A+ASR+IASD+ YK A+ +
Sbjct: 1463 PDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLR 1522

Query: 302  QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361
             +G  IG RS  +DP++    NV ++Q+D  YKK +   +++     D   +  AK  Q 
Sbjct: 1523 DRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQ 1582

Query: 362  LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397
            LASDV YR  L   +C P+Q  +  A+KA+ LQSDV
Sbjct: 1583 LASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDV 1618



 Score =  189 bits (481), Expect = 3e-48
 Identities = 133/443 (30%), Positives = 224/443 (50%), Gaps = 55/443 (12%)

Query: 1   MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
           +L++   A   S+  Y +D+   + KG          + AK + E+AS+ +Y + Y+K++
Sbjct: 213 LLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEM 272

Query: 61  GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQ-AKKCQVL 119
               G        + +     A  Q  + Y + YE+ +G  + P  +    Q AKK   L
Sbjct: 273 ---RGMAGPAIGAEGILTRECAD-QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHEL 328

Query: 120 VSDIDYRNYLHQ------WTCLPDQNDVI--QAKKAYDLQSDNLYKSDLE-----WLKGI 166
            SDI YR   ++      +  LP Q++++  QA+    L S+N YK + +       +G+
Sbjct: 329 ASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGV 388

Query: 167 GWLPEGSVEVMRVKN-AQNL-------------------------------LNERLYRIK 194
           G +   ++  M+V + A N+                               L +  YR  
Sbjct: 389 G-MDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQS 447

Query: 195 PEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQI 254
            + LK++S+ DTP+++QAKINA Q+S   YR  +EK K N  +P D P ++++K NA   
Sbjct: 448 IDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLF 507

Query: 255 SNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKE 314
           S  +Y++ WE  K  G++++ DA+ +  AKAS ++AS+  YK  YEK KG  +G      
Sbjct: 508 SEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMG----TA 563

Query: 315 DPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYRHYLHH 374
           D +L+ +  + KM ++  YKK + + K +  +P+DMV+I  AK+ Q LASD+DYR  LH 
Sbjct: 564 DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHE 623

Query: 375 WSCFPDQNDVIQARKAYDLQSDV 397
           ++  P+      A+KAY LQS++
Sbjct: 624 YTVLPEDMKTQWAKKAYGLQSEL 646



 Score =  165 bits (418), Expect = 6e-41
 Identities = 80/187 (42%), Positives = 119/187 (63%)

Query: 3    QAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH 62
            +A +NAL +S+K+Y+  W  T+   YD R DAI  + A+ASREIAS+++YKE + +  G 
Sbjct: 1467 RARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGL 1526

Query: 63   HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSD 122
             +G+R++ DDP+    ++  ++QSD EYKK + KS+   ++  D   ++QAK+ Q L SD
Sbjct: 1527 QIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASD 1586

Query: 123  IDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNA 182
            + YR  L Q TC P+Q  +  A+KA+ LQSD  YKSDL   +G+GW P GS +V   + A
Sbjct: 1587 VHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRA 1646

Query: 183  QNLLNER 189
              L N R
Sbjct: 1647 AELANAR 1653



 Score =  101 bits (252), Expect = 1e-21
 Identities = 102/396 (25%), Positives = 183/396 (46%), Gaps = 27/396 (6%)

Query: 16  YQKDWNDTKQKG----YDIRA-DAIEIKHAKASREIASEYKYKEGYRKQL-GHHMGFRTL 69
           Y++D+N  K KG    + + A D + +K A++  ++ SE KYKE Y+  + G + G   +
Sbjct: 334 YRQDFN--KMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEG---V 388

Query: 70  QDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYL 129
             D +++ A+    + S+  YK  Y+     +N P  +    Q     V + D +YR  +
Sbjct: 389 GMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSI 448

Query: 130 H--QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLN 187
              +++ + D   ++QAK      S   Y++D E  K    LP+   ++++ K    L +
Sbjct: 449 DKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFS 508

Query: 188 ERLYRIKPEALK---FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLM 244
           E  Y+   E  K   F   +D   ++ AK +    S   Y+  +EK K      AD+ L+
Sbjct: 509 EVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLL 568

Query: 245 LQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKG 304
              +I A   S   Y++ +E+ K T + L  D + I+HAK ++ +ASD      Y K+  
Sbjct: 569 HSLQI-AKMSSEVEYKKGFEESK-TRFHLPMDMVNIRHAKKAQTLASD----LDYRKKLH 622

Query: 305 HYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALAS 364
            Y       ED K  WA     +Q++  YK      K    +    +++  AK+   L S
Sbjct: 623 EY---TVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS 679

Query: 365 DVDYRHYLHH--WSCFPDQNDVIQARKAYDLQSDVS 398
           + +YR  +    ++   D + +  A+K+ +LQS V+
Sbjct: 680 EKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVA 715



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 72/339 (21%), Positives = 133/339 (39%), Gaps = 57/339 (16%)

Query: 10   QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69
            Q+ ++L  +    + Q  + +  D + + HAK ++ +AS++ Y+  Y K       F  L
Sbjct: 1304 QLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK-------FTAL 1356

Query: 70   QDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY- 128
             +D K  WA  A  +QS+  YK      KGI    L    +  AKK   L+S+  YR   
Sbjct: 1357 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKP 1416

Query: 129  ------------------------------------LHQWTCLPDQNDVIQAKKAYDLQS 152
                                                LH++T +PD  D  +A+      S
Sbjct: 1417 DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLS 1476

Query: 153  DNLYKSDLEWLKGIGW------LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDT 206
            D +Y++  E  +   +      +P  +    R   +     E   R +   + + S+ D 
Sbjct: 1477 DKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDD 1536

Query: 207  PEVIQ-AKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWED 265
            P +     +  +Q S+  Y+  + K ++  +   D P +LQ+K +    S+  Y+Q    
Sbjct: 1537 PRMKHFLNVGRLQ-SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQ 1595

Query: 266  VKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKG 304
                      + +G++HA+ +  + SD  YK+     +G
Sbjct: 1596 PTCD-----PEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1629



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 72/284 (25%), Positives = 128/284 (45%), Gaps = 54/284 (19%)

Query: 135 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 191
           LPD   V  ++A+K+   +    Y  D E  +G G  P        R K A  L ++  Y
Sbjct: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193

Query: 192 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA-DTP-LMLQS 247
           +   +    +F+++VDTPE++++K  A   S+  Y   +E+++   + PA  TP   +  
Sbjct: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAK 253

Query: 248 KINALQISNKRYQQAWEDVK-MTGYDLRADAI---------------------------- 278
           + N L    + +QQ  ++++ M G  + A+ I                            
Sbjct: 254 RANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPA 313

Query: 279 ----GIQHAKASRDIASDYLYKTAYEKQKG--HYIGCRSAKEDPKLVWAANVLKMQNDRL 332
                 Q+AK + ++ASD  Y+  + K KG  HY     A+++  L  A +V K+ ++  
Sbjct: 314 MITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSL-PAQDNLVLKQAQSVNKLVSENK 372

Query: 333 YKKAYNDHK--AKISIPVDMVSISAAKEGQALASDV----DYRH 370
           YK+ Y +H       + +D  ++ A K G +LAS+V    DY+H
Sbjct: 373 YKENYQNHMRGRYEGVGMDRRTLHAMKVG-SLASNVAYKADYKH 415


>gi|46049105 nebulin-related anchoring protein isoform S [Homo
            sapiens]
          Length = 1730

 Score =  330 bits (846), Expect = 1e-90
 Identities = 167/395 (42%), Positives = 250/395 (63%)

Query: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61
            LQA  NA  +S KLY+  W + K KG+++R D++    AKA R++ASE KYKE Y +  G
Sbjct: 772  LQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRG 831

Query: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121
              +G + +Q D +   ++  +K+QS+ EYKK +E +K   +  LDM+ +V A+K Q L +
Sbjct: 832  KLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLAT 891

Query: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181
            D+ Y+   H +T LP    V  AKKAY LQSDN Y++D++W+KG+GW+  GS+ V + K 
Sbjct: 892  DVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKK 951

Query: 182  AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241
            A  L++E+ YR  P+ALKFTSI DTPE++QA+I+  Q  + LYR   E  K +    AD 
Sbjct: 952  AGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADL 1011

Query: 242  PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301
            P +L +K+NA+ IS  RY+++W  ++  GY LR DA+  Q AKAS +I SDY YK A+EK
Sbjct: 1012 PEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEK 1071

Query: 302  QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361
             KG  +G RS ++D  L  +     +Q+D  YKK +   KA+  +P+DM ++  AK+ Q 
Sbjct: 1072 MKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQT 1131

Query: 362  LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
            LAS+ DY+H L  ++   +   +  A+KA+ LQS+
Sbjct: 1132 LASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSE 1166



 Score =  300 bits (767), Expect = 2e-81
 Identities = 157/396 (39%), Positives = 241/396 (60%), Gaps = 4/396 (1%)

Query: 1   MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
           +++A  NA   S   Y++ W  TK KG++++ DA+ +  AKAS E+AS  KYKE Y K  
Sbjct: 532 LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591

Query: 61  GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
           G  MG      D + + ++  AK+ S+ EYKK +E+SK   + P+DM++I  AKK Q L 
Sbjct: 592 GKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 647

Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
           SD+DYR  LH++T LP+      AKKAY LQS+  YK+DL W+KG+GWL EGS+ + + K
Sbjct: 648 SDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAK 707

Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
            A  L++E+ YR + + LKFTS+ D+ ++  AK +    S   Y+   E+      +  D
Sbjct: 708 KAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 767

Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
            PL LQ++ NA  +S K Y+ +WE+ K  G++LR D++    AKA RD+AS+  YK  YE
Sbjct: 768 EPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYE 827

Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
           + +G  IG +  + D ++  +  + K+Q++  YKK + D K++  + +DMV +  A++ Q
Sbjct: 828 RSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQ 887

Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396
            LA+DV Y+   HH++  P    V  A+KAY LQSD
Sbjct: 888 HLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSD 923



 Score =  298 bits (764), Expect = 5e-81
 Identities = 150/397 (37%), Positives = 247/397 (62%)

Query: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60
            +L A +NA+ IS   Y++ W+  +  GY +R DA+  + AKAS EI S+YKYKE + K  
Sbjct: 1014 VLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK 1073

Query: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120
            G  +G R+L+DD     +++A  +QSD  YKK +E SK   + PLDM ++V AKK Q L 
Sbjct: 1074 GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLA 1133

Query: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180
            S+ DY++ L Q+T L +   +  AKKA+ LQS+NLY+SDL +++G+  +  G++E+   K
Sbjct: 1134 SNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRK 1193

Query: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240
             A  L++E  YR  P + K+T++ DTP ++ AK +    +E LY+ A E  +    +   
Sbjct: 1194 KASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLG 1253

Query: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300
             P  +++K NA  +S+ RY+++W +++  GY L  +A+  Q A+AS DIASD+LY+  + 
Sbjct: 1254 LPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFV 1313

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360
            K++G  IG +S ++DP++     + ++Q++  Y++     +A+  +P+DMV +  AK  Q
Sbjct: 1314 KERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQ 1373

Query: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397
            ALASD DYR   H ++  P+   +  A+KA+ LQS++
Sbjct: 1374 ALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSEL 1410



 Score =  283 bits (724), Expect = 2e-76
 Identities = 146/396 (36%), Positives = 241/396 (60%)

Query: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61
            ++A  NA  +S+  Y++ W + + +GY +  +A+  + A+AS +IAS++ Y+  + K+ G
Sbjct: 1258 IRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERG 1317

Query: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121
              +G ++++DDP+        ++QS+ +Y++    S+   + P+DM+ +V AK  Q L S
Sbjct: 1318 KLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALAS 1377

Query: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181
            D DYR   H++T LP+   +  AKKA+ LQS+  YKSDL  +KGIGWL   S ++   K 
Sbjct: 1378 DHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKK 1437

Query: 182  AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241
            A  L++E  YR KP+++KFT++VD+P+++ AK + +  +E +YR+   +      +  D 
Sbjct: 1438 AGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDH 1497

Query: 242  PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301
            P   ++++NAL +S+K Y+ +WE  +   YD R DAI  Q A+ASR+IASD+ YK A+ +
Sbjct: 1498 PDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLR 1557

Query: 302  QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361
             +G  IG RS  +DP++    NV ++Q+D  YKK +   +++     D   +  AK  Q 
Sbjct: 1558 DRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQ 1617

Query: 362  LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397
            LASDV YR  L   +C P+Q  +  A+KA+ LQSDV
Sbjct: 1618 LASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDV 1653



 Score =  191 bits (486), Expect = 8e-49
 Identities = 125/390 (32%), Positives = 202/390 (51%), Gaps = 14/390 (3%)

Query: 16  YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH-HMGFRTLQDDPK 74
           Y +++ + + KG          ++AK + E+AS+ KY++ + K  G  H      QD+  
Sbjct: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLV 357

Query: 75  SVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYLH--- 130
              A    K+ S+ EYKK  E S+G      +        K     SD  Y+ NY +   
Sbjct: 358 LKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMR 417

Query: 131 -QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNL--LN 187
            ++  +      + A K   L S+  YK+D +    I      +      + A  L  L 
Sbjct: 418 GRYEGVGMDRRTLHAMKVGSLASNVAYKADYK--HDIVDYNYPATLTPSYQTAMKLVPLK 475

Query: 188 ERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQS 247
           +  YR   + LK++S+ DTP+++QAKINA Q+S   YR  +EK K N  +P D P ++++
Sbjct: 476 DANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKA 535

Query: 248 KINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYI 307
           K NA   S  +Y++ WE  K  G++++ DA+ +  AKAS ++AS+  YK  YEK KG  +
Sbjct: 536 KTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAM 595

Query: 308 GCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVD 367
           G      D +L+ +  + KM ++  YKK + + K +  +P+DMV+I  AK+ Q LASD+D
Sbjct: 596 G----TADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLD 651

Query: 368 YRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397
           YR  LH ++  P+      A+KAY LQS++
Sbjct: 652 YRKKLHEYTVLPEDMKTQWAKKAYGLQSEL 681



 Score =  165 bits (418), Expect = 6e-41
 Identities = 80/187 (42%), Positives = 119/187 (63%)

Query: 3    QAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH 62
            +A +NAL +S+K+Y+  W  T+   YD R DAI  + A+ASREIAS+++YKE + +  G 
Sbjct: 1502 RARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGL 1561

Query: 63   HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSD 122
             +G+R++ DDP+    ++  ++QSD EYKK + KS+   ++  D   ++QAK+ Q L SD
Sbjct: 1562 QIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASD 1621

Query: 123  IDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNA 182
            + YR  L Q TC P+Q  +  A+KA+ LQSD  YKSDL   +G+GW P GS +V   + A
Sbjct: 1622 VHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRA 1681

Query: 183  QNLLNER 189
              L N R
Sbjct: 1682 AELANAR 1688



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 94/437 (21%), Positives = 183/437 (41%), Gaps = 92/437 (21%)

Query: 16  YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKS 75
           Y +D+   + KG          + AK + ++AS+ +YK G+ +++     F T+ D P+ 
Sbjct: 157 YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISR---FSTVVDTPEL 213

Query: 76  VWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQ-AKKCQVLVSDIDY-RNYLHQWT 133
           + +   A++QSD  Y + YE+ +G  + P  +    Q AK+   L SD+ Y + Y  +  
Sbjct: 214 LRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMR 273

Query: 134 CL-----------------------PDQND---------------VIQAKKAYDLQSDNL 155
            +                       P++ +                  AKKA++L SD  
Sbjct: 274 GMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIK 333

Query: 156 YKSDLEWLKGIGW---LP-EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI--VDTPE- 208
           Y+ D   +KG      LP + ++ + + ++   L++E  Y+   E+ +  SI   +TP+ 
Sbjct: 334 YRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQF 393

Query: 209 -------------------------------VIQAKINAVQI----SEPLYRNAWEKEKA 233
                                          + +  ++A+++    S   Y+  ++ +  
Sbjct: 394 RNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIV 453

Query: 234 NVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDY 293
           + N PA      Q+ +  + + +  Y+Q+ + +K   Y    D   I  AK +    S  
Sbjct: 454 DYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLK---YSSVTDTPQIVQAKINAQQLSHV 510

Query: 294 LYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAK-ISIPVDMVS 352
            Y+  YEK K +Y      ++ P+LV A    K+ ++  YK+ +   K K   + +D +S
Sbjct: 511 NYRADYEKNKLNY---TLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMS 567

Query: 353 ISAAKEGQALASDVDYR 369
           + AAK    LAS++ Y+
Sbjct: 568 LLAAKASGELASNIKYK 584



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 72/339 (21%), Positives = 133/339 (39%), Gaps = 57/339 (16%)

Query: 10   QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69
            Q+ ++L  +    + Q  + +  D + + HAK ++ +AS++ Y+  Y K       F  L
Sbjct: 1339 QLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK-------FTAL 1391

Query: 70   QDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY- 128
             +D K  WA  A  +QS+  YK      KGI    L    +  AKK   L+S+  YR   
Sbjct: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKP 1451

Query: 129  ------------------------------------LHQWTCLPDQNDVIQAKKAYDLQS 152
                                                LH++T +PD  D  +A+      S
Sbjct: 1452 DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLS 1511

Query: 153  DNLYKSDLEWLKGIGW------LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDT 206
            D +Y++  E  +   +      +P  +    R   +     E   R +   + + S+ D 
Sbjct: 1512 DKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDD 1571

Query: 207  PEVIQ-AKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWED 265
            P +     +  +Q S+  Y+  + K ++  +   D P +LQ+K +    S+  Y+Q    
Sbjct: 1572 PRMKHFLNVGRLQ-SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQ 1630

Query: 266  VKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKG 304
                      + +G++HA+ +  + SD  YK+     +G
Sbjct: 1631 PTCD-----PEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1664



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 67/278 (24%), Positives = 113/278 (40%), Gaps = 59/278 (21%)

Query: 135 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 191
           LPD   V  ++A+K+   +    Y  D E  +G G  P        R K A  L ++  Y
Sbjct: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193

Query: 192 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA-DTPLMLQSK 248
           +   +    +F+++VDTPE++++K  A   S+  Y   +E+++   + PA  TP      
Sbjct: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITP------ 247

Query: 249 INALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIG 308
                                           Q AK + ++ASD  Y   Y+K+     G
Sbjct: 248 ------------------------------AYQIAKRANELASDVRYHQQYQKEMRGMAG 277

Query: 309 CRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMV-SISAAKEGQALASDVD 367
                E       A+    Q  + Y + Y +H+ K S P  +  +   AK+   LASD+ 
Sbjct: 278 PAIGAEGILTRECAD----QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIK 333

Query: 368 YRHYLH------HWSCFPDQNDVI--QARKAYDLQSDV 397
           YR   +      H+   P Q++++  QA+    L S+V
Sbjct: 334 YRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371


>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
          Length = 1014

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 103/428 (24%), Positives = 192/428 (44%), Gaps = 35/428 (8%)

Query: 6   INALQISNKLYQKDWNDTKQKGYDIRADAIE---IKHAKASREIASEYKYKEGYRKQLGH 62
           + A ++S+++  K+  D + K      + +E    +  + +  +AS  KYK+  +     
Sbjct: 220 VEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNM--- 276

Query: 63  HMGFRTLQDDPKSVWAIH---AAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVL 119
                 + D P  ++  H   A+K+ S REYKK +E++KG+++   D +  +  K   VL
Sbjct: 277 ---HDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVL 333

Query: 120 VSDIDYRNYLHQWTCLP-----DQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLP-EG 172
            S + Y+    +    P     +      +K+A  +QS+ +YK D E  +KG   L  + 
Sbjct: 334 QSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDK 393

Query: 173 SVEVMRVKNAQNLLNERLYR------IKPEALKFTSIVDTPEVIQAKINAVQISEPLYRN 226
           + E + VK   NLL E+ Y+      IK + ++  S  +  ++ +AK  +   SE  Y+ 
Sbjct: 394 TPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNS--EVLDIQRAKRASEMASEKEYKK 451

Query: 227 AWEK--EKANVNVPADTPLMLQSKINALQISNKRYQQAWE-DVKMTGYDLRADAIGIQHA 283
             E   +   +    DT  M  +K  A   S K Y++  E ++K  G  +  D + +Q A
Sbjct: 452 DLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRA 511

Query: 284 KASRDIASDYLYKTAYEKQ-KGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKA 342
           K + ++AS   YK   E + KG   G + + + P ++ A    ++ + R YK       +
Sbjct: 512 KKASEMASQKQYKKDLENEIKGK--GMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLS 569

Query: 343 KISIPVDMVSISAAKEGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDVSVSPR 402
             S   D   I   K  Q   S V Y+  +   +   D  ++ + +K  + Q+  SV  +
Sbjct: 570 NYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKK--NQQNISSVKYK 627

Query: 403 KQVPHCFA 410
           +++ H  A
Sbjct: 628 EEIKHATA 635



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 83/349 (23%), Positives = 140/349 (40%), Gaps = 43/349 (12%)

Query: 12  SNKLYQKDW-NDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQ 70
           S K Y+KD  N+ K KG  +  D  +I  AK + EI S+ KYK+   K L +   + T+ 
Sbjct: 519 SQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSN---YSTIA 575

Query: 71  DDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH 130
           D P+    I   K          Y+K  G      D   I + KK Q  +S + Y+  + 
Sbjct: 576 DTPE----IQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIK 631

Query: 131 QWTCLPDQNDVIQAKKAYDLQSDNLYKSD----------------------LEWLKGIGW 168
             T + D  ++ + K+     S+  YK                        L  +K  G 
Sbjct: 632 HATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKGE 691

Query: 169 LPEGSV-----EVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPL 223
           L  G+      E+ R K  Q  ++   YR   +  + T++  TPE+ + K N   IS   
Sbjct: 692 LQRGTAISDPPELKRAKENQKNISNVYYR--GQLGRATTLSVTPEMERVKKNQENISSVK 749

Query: 224 YRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHA 283
           Y    ++ K   ++  DTP M   K     IS  +Y + +E  K  G+    D    +  
Sbjct: 750 YTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERV 809

Query: 284 KASRDIASDYLYKTAY------EKQKGHYIGCRSAKEDPKLVWAANVLK 326
           + +  + SD  YK  +      +++ G  +  +  + DP  ++  + L+
Sbjct: 810 RKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLDPLE 858



 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 99/442 (22%), Positives = 179/442 (40%), Gaps = 60/442 (13%)

Query: 10  QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69
           Q+ +++  K  +D   KG+   A   E    K + E+ ++++    YRK +     +   
Sbjct: 119 QLQSEVAYKQKHDAA-KGFSDYAHMKEPPEVKHAMEV-NKHQSNISYRKDVQDTHTYSAE 176

Query: 70  QDDPKSVWAIHAAKIQSDREYKKAY----------------------------------- 94
            D P    A   +KI S+ EYKK                                     
Sbjct: 177 LDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFD 236

Query: 95  --EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQW----TCLPDQNDVIQAKKAY 148
              K K  H  PL+  S  Q +    L S++ Y+  +       + LP+   +    KA 
Sbjct: 237 NEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKAS 296

Query: 149 DLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK---FTSIVD 205
            + S   YK   E  KG+      +VE +  K    L ++  Y+ + E  K       V+
Sbjct: 297 KMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVE 356

Query: 206 TPEVIQAKINAVQISEPLYRNAWEKE-KANVNVPAD-TPLMLQSKINALQISNKRYQQAW 263
           TP    +K      SE +Y+  +EKE K   ++  D TP  L  K     +  K Y++  
Sbjct: 357 TPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDL 416

Query: 264 E-DVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK-QKGHYIGCRSAKEDPKLVWA 321
           E ++K  G +L ++ + IQ AK + ++AS+  YK   E   KG   G ++  +  ++  A
Sbjct: 417 ENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGK--GMQAGTDTLEMQHA 474

Query: 322 ANVLKMQNDRLYKK-AYNDHKAK-ISIPVDMVSISAAKEGQALASDVDYRHYLHH----- 374
               ++ +++ YK+    + K K + +  D + +  AK+   +AS   Y+  L +     
Sbjct: 475 KKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGK 534

Query: 375 -WSCFPDQNDVIQARKAYDLQS 395
                 D  D+++A++  ++ S
Sbjct: 535 GMQVSMDIPDILRAKRTSEIYS 556



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 65/321 (20%), Positives = 124/321 (38%), Gaps = 27/321 (8%)

Query: 66  FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 125
           ++ + +D     A    ++ SD  YK+ ++KSK       D   +   K     +S+  Y
Sbjct: 30  YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKY 89

Query: 126 RNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL-----PEGSV 174
           +  +        +  +P   D + A +   LQS+  YK   +  KG         P    
Sbjct: 90  KGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVK 149

Query: 175 EVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNA---WEKE 231
             M V   Q+ ++ R  +   +   +++ +D P++  A   +  IS   Y+       KE
Sbjct: 150 HAMEVNKHQSNISYR--KDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKE 207

Query: 232 KANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIAS 291
            A +  P     +  SK+++     +++    +D K     L  ++   +  + +  +AS
Sbjct: 208 PAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPL--ESASFRQNQLAATLAS 265

Query: 292 DYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVL---KMQNDRLYKKAYNDHKAKISIPV 348
           +  YK   +             + P L++  +VL   KM + R YKK + ++K       
Sbjct: 266 NVKYKKDIQNMHD------PVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDA 319

Query: 349 DMVSISAAKEGQALASDVDYR 369
           D V     K    L S V Y+
Sbjct: 320 DAVEHLHHKGNAVLQSQVKYK 340


>gi|47087157 nebulette non-muscle isoform [Homo sapiens]
          Length = 270

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 7/124 (5%)

Query: 180 KNAQNLLNERLYRIKPEA------LKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKA 233
           K A N+ N + Y  KP          FT++ DTPE ++ K  +   S+  Y+  +E+ K 
Sbjct: 36  KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95

Query: 234 N-VNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASD 292
              ++  DTP + + K    QISN +Y + +E  K  G+    D    +  + +  + SD
Sbjct: 96  RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSD 155

Query: 293 YLYK 296
             YK
Sbjct: 156 AAYK 159



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 2/76 (2%)

Query: 16  YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKS 75
           Y++D+ ++K +G+ I  D  E++  K ++E  S  KY E + K  G   GF  + DDP +
Sbjct: 86  YKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVT 143

Query: 76  VWAIHAAKIQSDREYK 91
                  ++ SD  YK
Sbjct: 144 ERVRKNTQVVSDAAYK 159



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 4/98 (4%)

Query: 132 WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERL 190
           +T + D  + ++ K+  +LQS   YK D E  KG G+ +   + E+ R+K  Q  ++   
Sbjct: 62  FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 191 YRIKPEALK---FTSIVDTPEVIQAKINAVQISEPLYR 225
           Y    E  K   FT +VD P   + + N   +S+  Y+
Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 2/103 (1%)

Query: 232 KANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIAS 291
           K +    ADTP  L+ K  +   S  +Y++ +E+ K  G+ +  D   +Q  K +++  S
Sbjct: 59  KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 292 DYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYK 334
           +  Y   +EK KG   G     +DP         ++ +D  YK
Sbjct: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 31/130 (23%), Positives = 60/130 (46%), Gaps = 12/130 (9%)

Query: 39  HAKASREIASEYKYKEGYRKQL---GHH--MGFRTLQDDPKSVWAIHAAKIQSDREYKKA 93
           H +  +   +   YK GY K+     H+    F T+ D P+++     +++QS  +YK+ 
Sbjct: 31  HCEVCKMALNMNNYK-GYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRD 89

Query: 94  YEKSKGI-HNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKA 147
           +E+SKG   +   D   + + K+ Q  +S++ Y     +     +T + D     + +K 
Sbjct: 90  FEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKN 149

Query: 148 YDLQSDNLYK 157
             + SD  YK
Sbjct: 150 TQVVSDAAYK 159


>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
          Length = 261

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 13/135 (9%)

Query: 180 KNAQNLLNERLYRIKPEA------LKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKA 233
           K   N+ N + Y  KP          FT + DTPE ++ K  +   S+  Y+  +EK K 
Sbjct: 36  KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95

Query: 234 -NVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASD 292
              +V ADTP + + K    QISN +Y + +E  +M        + G       RD    
Sbjct: 96  KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM------GPSGGEGMEPERRDSQDG 149

Query: 293 YLYKTAYEKQKGHYI 307
             Y+   E+Q+ H+I
Sbjct: 150 SSYRRPLEQQQPHHI 164



 Score = 35.8 bits (81), Expect = 0.072
 Identities = 31/129 (24%), Positives = 59/129 (45%), Gaps = 8/129 (6%)

Query: 39  HAKASREIASEYKYKEGYRKQL---GHH--MGFRTLQDDPKSVWAIHAAKIQSDREYKKA 93
           H +  +   +   YK GY K+     H+    F  + D P+++     +++QS   YK+ 
Sbjct: 31  HCETCKMTLNMKNYK-GYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEE 89

Query: 94  YEKSKGI-HNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQS 152
           +EK+KG   +   D   + + KK Q  +S+I Y     +    P   + ++ ++  D Q 
Sbjct: 90  FEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR-DSQD 148

Query: 153 DNLYKSDLE 161
            + Y+  LE
Sbjct: 149 GSSYRRPLE 157



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 13/43 (30%), Positives = 25/43 (58%)

Query: 16  YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRK 58
           Y++++   K KG+ + AD  E++  K +++  S  KY E + K
Sbjct: 86  YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 64/366 (17%), Positives = 152/366 (41%), Gaps = 47/366 (12%)

Query: 3   QAHINALQISNKLYQKDWNDTKQK----GYDIRADAIEIKHAKASREIASEYKYKEGYRK 58
           +A +  ++  NK+  +   +T  K     ++ R    E++H K   E A E + +  + +
Sbjct: 579 EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLE 638

Query: 59  QLGHHMGFR--TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKC 116
           +    +  +   L+   + + A+     + +RE +K  +      N    + S+ + +  
Sbjct: 639 KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESL-EKENS 697

Query: 117 QVLVSDIDYRNYLHQWTC-------LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 169
           Q+   +++ R  +    C       L  +N  ++++K    +   L K+  +  + +   
Sbjct: 698 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757

Query: 170 PEG-SVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAW 228
            +G  +E  R++      N+++ +++ E      +    + +Q  +  ++IS    +   
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESE---LQDLEMENQTLQKNLEELKISS---KRLE 811

Query: 229 EKEKANVNVPADTPLMLQSKINALQISNKRYQQAWE--DVKMTGYDLRADAIGIQHAKAS 286
           + EK N ++  +T  + + K   L+  NKR +Q  E  D  +   +++   +  ++   S
Sbjct: 812 QLEKENKSLEQETSQLEKDK-KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLS 870

Query: 287 RDIASDYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISI 346
           ++I    +YK +          C   KE          L+ +N  L K+A  D K  +++
Sbjct: 871 KEIG---IYKES----------CVRLKE----------LEKENKELVKRATIDIKTLVTL 907

Query: 347 PVDMVS 352
             D+VS
Sbjct: 908 REDLVS 913


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 32.0 bits (71), Expect = 1.0
 Identities = 64/366 (17%), Positives = 152/366 (41%), Gaps = 47/366 (12%)

Query: 3   QAHINALQISNKLYQKDWNDTKQK----GYDIRADAIEIKHAKASREIASEYKYKEGYRK 58
           +A +  ++  NK+  +   +T  K     ++ R    E++H K   E A E + +  + +
Sbjct: 579 EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLE 638

Query: 59  QLGHHMGFR--TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKC 116
           +    +  +   L+   + + A+     + +RE +K  +      N    + S+ + +  
Sbjct: 639 KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESL-EKENS 697

Query: 117 QVLVSDIDYRNYLHQWTC-------LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 169
           Q+   +++ R  +    C       L  +N  ++++K    +   L K+  +  + +   
Sbjct: 698 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757

Query: 170 PEG-SVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAW 228
            +G  +E  R++      N+++ +++ E      +    + +Q  +  ++IS    +   
Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESE---LQDLEMENQTLQKNLEELKISS---KRLE 811

Query: 229 EKEKANVNVPADTPLMLQSKINALQISNKRYQQAWE--DVKMTGYDLRADAIGIQHAKAS 286
           + EK N ++  +T  + + K   L+  NKR +Q  E  D  +   +++   +  ++   S
Sbjct: 812 QLEKENKSLEQETSQLEKDK-KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLS 870

Query: 287 RDIASDYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISI 346
           ++I    +YK +          C   KE          L+ +N  L K+A  D K  +++
Sbjct: 871 KEIG---IYKES----------CVRLKE----------LEKENKELVKRATIDIKTLVTL 907

Query: 347 PVDMVS 352
             D+VS
Sbjct: 908 REDLVS 913


>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
          Length = 1844

 Score = 30.0 bits (66), Expect = 4.0
 Identities = 38/159 (23%), Positives = 60/159 (37%), Gaps = 20/159 (12%)

Query: 103 TPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEW 162
           TPL+M S V+ KK +  V      N  HQ   +  +N+      + D + D    +D   
Sbjct: 100 TPLEMFSNVEFKKKRKRV------NLSHQLNNIKTENEAPIEISSDDSKEDYSLNNDFV- 152

Query: 163 LKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEP 222
                   E S  V+R K    +L E +   K +    TS+ ++      K+N  Q +  
Sbjct: 153 --------ESSTSVLRYKKQVEVLAENIQDTKSQPNTMTSLQNS-----KKVNPKQGTTK 199

Query: 223 LYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQ 261
                  K K    V     L L  ++N L+   K  +Q
Sbjct: 200 NDFKKLRKRKCRDVVDLSESLPLAEELNLLKKDGKDTKQ 238


>gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]
          Length = 5890

 Score = 29.6 bits (65), Expect = 5.2
 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 2/60 (3%)

Query: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYND--HKAKISIPVDMVSISAAKE 358
            K KGHY    S  E  KL  +   L  +  RL   + ND  +K  I +P   +S+S  KE
Sbjct: 5831 KSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPEVELSVSTKKE 5890


>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
           sapiens]
          Length = 1710

 Score = 29.6 bits (65), Expect = 5.2
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%)

Query: 118 VLVSDIDYRNYL--HQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVE 175
           V + DI+ RN +  H+WT     +   + K    L +  +   D  +L G+ W   G  E
Sbjct: 560 VYLGDINSRNMIRTHEWT----HHQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDE 615

Query: 176 VMRVKNAQNLLNERLYRIK 194
             R+KN  +LL + L   K
Sbjct: 616 AHRLKNDDSLLYKTLIDFK 634


>gi|4885237 forkhead box C2 [Homo sapiens]
          Length = 501

 Score = 28.9 bits (63), Expect = 8.8
 Identities = 11/40 (27%), Positives = 25/40 (62%)

Query: 335 KAYNDHKAKISIPVDMVSISAAKEGQALASDVDYRHYLHH 374
           +A +DH +  + P+  ++++A +EG   A+   ++H+ HH
Sbjct: 356 EALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHH 395


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.130    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,361,125
Number of Sequences: 37866
Number of extensions: 579296
Number of successful extensions: 2100
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1450
Number of HSP's gapped (non-prelim): 92
length of query: 410
length of database: 18,247,518
effective HSP length: 105
effective length of query: 305
effective length of database: 14,271,588
effective search space: 4352834340
effective search space used: 4352834340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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