BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|169217576 PREDICTED: similar to nebulin [Homo sapiens] (410 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|169217576 PREDICTED: similar to nebulin [Homo sapiens] 837 0.0 gi|115527120 nebulin [Homo sapiens] 503 e-142 gi|239752495 PREDICTED: similar to nebulin [Homo sapiens] 357 1e-98 gi|46049092 nebulin-related anchoring protein isoform C [Homo sa... 330 1e-90 gi|46049105 nebulin-related anchoring protein isoform S [Homo sa... 330 1e-90 gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 91 1e-18 gi|47087157 nebulette non-muscle isoform [Homo sapiens] 50 4e-06 gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 47 4e-05 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 32 1.0 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 32 1.0 gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] 30 4.0 gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens] 30 5.2 gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 30 5.2 gi|4885237 forkhead box C2 [Homo sapiens] 29 8.8 >gi|169217576 PREDICTED: similar to nebulin [Homo sapiens] Length = 410 Score = 837 bits (2163), Expect = 0.0 Identities = 410/410 (100%), Positives = 410/410 (100%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDVSVSPRKQVPHCFA 410 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDVSVSPRKQVPHCFA Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDVSVSPRKQVPHCFA 410 >gi|115527120 nebulin [Homo sapiens] Length = 6669 Score = 503 bits (1295), Expect = e-142 Identities = 238/396 (60%), Positives = 312/396 (78%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 ++ A +N + S+KLY+ ++K++GYD+R DAI I+ AKASR+IAS+YKYKEGYRKQL Sbjct: 3472 IMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQL 3531 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 GHH+G R ++DDPK +W+IH AKIQSDREYKK +EK K ++P+DM+ +V AKKCQ+LV Sbjct: 3532 GHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILV 3591 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 SDIDY++ LH+WTCLPDQNDVIQA+KAYDLQSD +YKSDLEWL+GIGW+P GSVEV +VK Sbjct: 3592 SDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVK 3651 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A +L++R YR + LKFT I DTPE++ AK NA+ +S+ LY AW+ +K +++V D Sbjct: 3652 RAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPD 3711 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 TP +L +K N+ IS K Y + W++ KM YDLRADAI I+ AKASRDIASDY YK AYE Sbjct: 3712 TPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYE 3771 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 KQKGH+IG +S ++DPK++ A + K+Q++R YKK + K K S PVDM+SI AK+ Q Sbjct: 3772 KQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQ 3831 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 L +D+DYR+YLH W+C PDQND+IQA+KAYDLQSD Sbjct: 3832 TLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSD 3867 Score = 501 bits (1291), Expect = e-142 Identities = 240/396 (60%), Positives = 310/396 (78%), Gaps = 1/396 (0%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 +L A N+ IS KLY K W+++K K YD+RADAI IK AKASR+IAS+YKYKE Y KQ Sbjct: 3715 ILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQK 3774 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 GHH+G ++++DDPK + AIHA KIQS+REYKK ++K K ++P+DM+SI+ AKKCQ LV Sbjct: 3775 GHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLV 3834 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 +DIDYRNYLH+WTC+PDQND+IQAKKAYDLQSD LYK+DLEWL+GIGW+P+GS EV+RVK Sbjct: 3835 TDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVK 3894 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 NAQN+ + +YR LK+TSIVDTPEV+ AK NA IS P YR W+K+K ++++ D Sbjct: 3895 NAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPD 3954 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 TP + ++ NAL +SNK Y++ W+++K G D+R DAI IQ AKASR+IASDY YK +E Sbjct: 3955 TPEINLARANALNVSNKLYREGWDEMK-AGCDVRLDAIPIQAAKASREIASDYKYKLDHE 4013 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 KQKGHY+G +A++D K+ WA K+QN+R Y+ + KAKI PVDM+SI +K Q Sbjct: 4014 KQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQ 4073 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 AL SD+DYR+YLH W+C PDQNDVIQA+KAY+LQSD Sbjct: 4074 ALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSD 4109 Score = 494 bits (1272), Expect = e-140 Identities = 232/396 (58%), Positives = 303/396 (76%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 ++ A N + S LY++ + K++GYD+R+DAI I AKASR+IAS+YKYKE YRKQL Sbjct: 3229 IMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQL 3288 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 GHH+G R + DDPK +W++H AK+QSDREYKK +EK K +++P+DM+ IV AKKCQ LV Sbjct: 3289 GHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLV 3348 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 SD+DY++ LH+W CLPDQND+I A+KAYDLQSDNLYKSDLEW+KGIGW+P S+EV+R K Sbjct: 3349 SDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAK 3408 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A LL++ +YR +PE LKFTSI DTPE + AK NA+ +++ LY AW+ +K ++V D Sbjct: 3409 RAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPD 3468 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 TP ++ +K+N + S+K Y+ A E+ K GYDLR DAI IQ AKASRDIASDY YK Y Sbjct: 3469 TPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYR 3528 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 KQ GH+IG R+ K+DPK++W+ +V K+Q+DR YKK + K K S PVDM+ + AK+ Q Sbjct: 3529 KQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQ 3588 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 L SD+DY+H LH W+C PDQNDVIQARKAYDLQSD Sbjct: 3589 ILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSD 3624 Score = 483 bits (1244), Expect = e-136 Identities = 223/396 (56%), Positives = 301/396 (76%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 ++ A N + S LY+ + K+KGYD+R+DAI I AKASR++ S+YKYK+GYRKQL Sbjct: 2986 IMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQL 3045 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 GHH+G R ++DDPK +W++H AKIQSDREYKK +EK K ++P+DM+ +V AKKCQ LV Sbjct: 3046 GHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 3105 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 SD+DY+NYLH+WTCLPDQNDVI A++AYDLQSDN+YKSDL+WL+GIGW+P GS++V++ K Sbjct: 3106 SDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCK 3165 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A +L++ +YR P+ LKFTS+ D+ E + AK NA+ +++ LY AW+K+K V++ D Sbjct: 3166 RAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPD 3225 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 TP ++ ++ N + S Y+QA E+ K GYDLR+DAI I AKASRDIASDY YK AY Sbjct: 3226 TPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYR 3285 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 KQ GH+IG R+ +DPK++W+ ++ K+Q+DR YKK + +K + S PVDM+ I AK+ Q Sbjct: 3286 KQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQ 3345 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 L SDVDY+H LH W C PDQND+I ARKAYDLQSD Sbjct: 3346 TLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSD 3381 Score = 478 bits (1231), Expect = e-135 Identities = 223/393 (56%), Positives = 298/393 (75%) Query: 4 AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHH 63 A N + S+KLY+ + + K+KGYD+ DAI IK AKASREIASEYKYKEG+RKQLGHH Sbjct: 2503 AKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHH 2562 Query: 64 MGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDI 123 +G R ++DDPK +W++H AKIQSDREYKK +EK K ++P+DM+ +V AKKCQ LVSD+ Sbjct: 2563 IGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDV 2622 Query: 124 DYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183 DY+NYLHQWTCLPDQ+DVI A++AYDLQSDNLYKSDL+WLKGIGW+ GS+E + K A Sbjct: 2623 DYKNYLHQWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRAT 2682 Query: 184 NLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPL 243 +L++ +YR P+ KF+S++D+ ++ AK NA+ ++ LY AW+K+K V++ DTP Sbjct: 2683 QILSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPE 2742 Query: 244 MLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQK 303 +L +K N + S K Y+ E+ K GYD+R DAI I+ AKASRDIAS++ YK Y KQ Sbjct: 2743 VLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQL 2802 Query: 304 GHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALA 363 GH+IG R+ ++DPK++W+ +V K+Q+DR YKK + K K S PVDM+ + AK+ Q L Sbjct: 2803 GHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 2862 Query: 364 SDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 SDVDY++YLH W+C PDQ+DVI AR+AYDLQSD Sbjct: 2863 SDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSD 2895 Score = 478 bits (1230), Expect = e-135 Identities = 222/396 (56%), Positives = 300/396 (75%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 +L A N + S KLY+ + K+KGYD+R DAI IK AKASR+IASE+KYKEGYRKQL Sbjct: 2743 VLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQL 2802 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 GHH+G R ++DDPK +W++H AKIQSDREYKK +EK K ++P+DM+ +V AKKCQ LV Sbjct: 2803 GHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLV 2862 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 SD+DY+NYLHQWTCLPDQ+DVI A++AYDLQSDN+YKSDL+W++GIGW+ GS++V + K Sbjct: 2863 SDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCK 2922 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A +L++++YR P+ KFTS+ D+ E + AK NA+ +++ LY AW+K+K +++ D Sbjct: 2923 RATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPD 2982 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 TP ++ ++ N + S Y+ A E+ K GYDLR+DAI I AKASRD+ SDY YK Y Sbjct: 2983 TPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYR 3042 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 KQ GH+IG R+ ++DPK++W+ +V K+Q+DR YKK + K K S PVDM+ + AK+ Q Sbjct: 3043 KQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQ 3102 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 L SDVDY++YLH W+C PDQNDVI AR+AYDLQSD Sbjct: 3103 TLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSD 3138 Score = 477 bits (1227), Expect = e-135 Identities = 223/396 (56%), Positives = 300/396 (75%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 +LQA N S KLY+ W + +KGYD+ DAI ++ AKASR+IAS+YKYK+GYRKQL Sbjct: 2257 ILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQL 2316 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 GHH+GFR+LQDDPK V +++ AK+QS+REYKK +EK K ++P+DM+ +V AKKCQ LV Sbjct: 2317 GHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELV 2376 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 SD+DY+NYLHQWTCLPDQNDV+QAKK Y+LQS+NLYKSDLEWL+GIGW P GS+E + K Sbjct: 2377 SDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNK 2436 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A +++E+ YR P+ KFTSI D +++ AK NA S+ LYR AW+K+K +++ D Sbjct: 2437 RASEIISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPD 2496 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 TP ++ +K N + S+K Y+ +E++K GYDL DAI I+ AKASR+IAS+Y YK + Sbjct: 2497 TPDIVLAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFR 2556 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 KQ GH+IG R+ ++DPK++W+ +V K+Q+DR YKK + K K S PVDM+ + AK+ Q Sbjct: 2557 KQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQ 2616 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 L SDVDY++YLH W+C PDQ+DVI AR+AYDLQSD Sbjct: 2617 TLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSD 2652 Score = 420 bits (1079), Expect = e-117 Identities = 206/393 (52%), Positives = 275/393 (69%), Gaps = 2/393 (0%) Query: 4 AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHH 63 A NAL +SNKLY++ W++ K G D+R DAI I+ AKASREIAS+YKYK + KQ GH+ Sbjct: 3961 ARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHY 4019 Query: 64 MGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDI 123 +G T +DD K WA+ A K+Q++REY+ + K K +P+DM+SI+ +K Q LVSD+ Sbjct: 4020 VGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDM 4079 Query: 124 DYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183 DYRNYLHQWTC+PDQNDVIQAKKAY+LQSDN+YK+DLEWL+GIGW+P SV V K+A Sbjct: 4080 DYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAA 4139 Query: 184 NLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPL 243 ++ +E+ YR K E L FT + D + + AK + + + YR W K+ + +TPL Sbjct: 4140 DIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTL-TETPL 4198 Query: 244 MLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQK 303 + ++ A + Y++ WE K TGY L DA+ HA D+ S+ YK + KQK Sbjct: 4199 LHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQK 4258 Query: 304 GHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALA 363 GHY+G + ++DPKLVW + ++QN+RLYK+ Y+ KAKI+IP DMVS+ AAK+GQ L Sbjct: 4259 GHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLV 4318 Query: 364 SDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 SD+DYR+YLH W C PDQNDVIQARKAYDLQSD Sbjct: 4319 SDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSD 4351 Score = 392 bits (1006), Expect = e-109 Identities = 192/397 (48%), Positives = 269/397 (67%), Gaps = 1/397 (0%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 ++ A NA+ +S+KLY+ ++K+KGYD+R DAI IK AKASR+IAS+YKYK Y K Sbjct: 2013 IILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNYEKGK 2072 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 G +GFR+L+DDPK V ++ AK+QSDREYKK YE +K ++TP DM+S+ AK Q + Sbjct: 2073 GKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDAQANI 2132 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRV 179 ++ +Y++ +H++ LPD ++ + +QSDN YK D EW KG+GW P GS+EV + Sbjct: 2133 TNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKA 2192 Query: 180 KNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA 239 K A +++ YR P +F + D+ +++ AK NA +++ LY W K+K ++V Sbjct: 2193 KKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMP 2252 Query: 240 DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299 DTP +LQ+K N S K Y+ WE+ GYDL DAI +Q AKASRDIASDY YK Y Sbjct: 2253 DTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPVDAISVQLAKASRDIASDYKYKQGY 2312 Query: 300 EKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEG 359 KQ GH++G RS ++DPKLV + NV KMQ++R YKK + K K S PVDM+ + AK+ Sbjct: 2313 RKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVLAKKC 2372 Query: 360 QALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Q L SDVDY++YLH W+C PDQNDV+QA+K Y+LQS+ Sbjct: 2373 QELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQSE 2409 Score = 380 bits (977), Expect = e-106 Identities = 195/396 (49%), Positives = 262/396 (66%), Gaps = 1/396 (0%) Query: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 +QA +NAL +S+ Y+ DW T KGYD+R DAI I AK+SR IAS+ KYKE Y K G Sbjct: 1526 IQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKG 1585 Query: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 +GF +LQDDPK V ++ AKIQSDREYKK YE SK ++TPLDM+S+ AKK Q + + Sbjct: 1586 KQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQEVAT 1645 Query: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRVK 180 + +YR H +T LPD +V ++ A +QSDNLYKSD W+KGIGW+P S+EV + K Sbjct: 1646 NANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKAK 1705 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A +L+E+ YR PE LKFT +DT E K N + + + LY W K+K ++V D Sbjct: 1706 KAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPD 1765 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 TP +L S++N + +S+K Y+ WE+ K GYDLR DAI I+ A+ASRDIASDY YK AYE Sbjct: 1766 TPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYE 1825 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 + KG +IG RS ++DPKLV V KMQ+DR YKK Y K PVDM+S+ AAK+ Q Sbjct: 1826 QAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQ 1885 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 +A++ +YR+ +H ++ PD A+ +QSD Sbjct: 1886 EVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSD 1921 Score = 379 bits (972), Expect = e-105 Identities = 195/396 (49%), Positives = 267/396 (67%), Gaps = 1/396 (0%) Query: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 +QA +NA IS +Y+ D D +KGYD+R DAI I+ AKA+R+ AS+ +YK+ Y K G Sbjct: 1038 IQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKG 1097 Query: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 +GF++LQDDPK V ++ AKIQSDREYKK YEK+K +NTP DM ++V AKK Q +VS Sbjct: 1098 KMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVS 1157 Query: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180 +++Y++ LH +T LPD D+ +K +QSDN+YK D W+KGIGW+P GS++V +VK Sbjct: 1158 NVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVK 1217 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A + LNE+ YR P+ LKFTSIVD+P ++QAK N Q+S+ LY+ E K + D Sbjct: 1218 KAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPD 1277 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 P LQ+K NA IS+ Y++ W D+ G ++ DAI I AKASR+IASDY YK AYE Sbjct: 1278 LPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYE 1337 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 K KG ++G RS ++DPKLV NV K+Q+DR YKK Y + K P DMVSI+AAK Q Sbjct: 1338 KSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQ 1397 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 +A++V+Y+ LHH++ PD + R +QSD Sbjct: 1398 DVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSD 1433 Score = 377 bits (967), Expect = e-104 Identities = 186/397 (46%), Positives = 272/397 (68%), Gaps = 1/397 (0%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 +L + +N + +S+KLY+ W + K+KGYD+R DAI IK A+ASR+IAS+YKYK+ Y + Sbjct: 1769 ILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAK 1828 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 G H+GFR+L+DDPK V + AK+QSDREYKK YEKSK +TP+DM+S+V AKK Q + Sbjct: 1829 GKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVA 1888 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDL-EWLKGIGWLPEGSVEVMRV 179 ++ +YRN +H + LPD AK +QSDN YK+D +++KGIGWLP GS+E + Sbjct: 1889 TNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKN 1948 Query: 180 KNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA 239 K A +++E+ YR P+ LK+++++D+ ++ A+ NA ++E LY+ AWE +K V++ Sbjct: 1949 KKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP 2008 Query: 240 DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299 D P ++ +K NA+ +S+K Y+ + E+ K GYDLR DAI I+ AKASRDIASDY YK Y Sbjct: 2009 DIPQIILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNY 2068 Query: 300 EKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEG 359 EK KG +G RS ++DPKLV + V KMQ+DR YKK Y + K P DM+S++AAK+ Sbjct: 2069 EKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDA 2128 Query: 360 QALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 QA ++ +Y+H +H + PD ++ R +QSD Sbjct: 2129 QANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSD 2165 Score = 362 bits (929), Expect = e-100 Identities = 188/396 (47%), Positives = 260/396 (65%), Gaps = 1/396 (0%) Query: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 LQA NA IS+ Y++DW+D KG ++ DAI I AKASR IAS+YKYKE Y K G Sbjct: 1282 LQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKG 1341 Query: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 H+GFR+LQDDPK V ++ AK+QSDREYKK YE +K ++TP DM+SI AK Q + + Sbjct: 1342 KHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVAT 1401 Query: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180 +++Y+ LH +T LPD + + +QSDN+YK + +LKGIGW+P GS+EV +VK Sbjct: 1402 NVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVK 1461 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A + LNER YR P+ +KFTS+ D+ ++ A+ N Q+S+ Y+ EK K + + Sbjct: 1462 KAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPE 1521 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 P +Q+K+NAL +S+ Y+ W+ GYDLR DAI I AK+SR+IASD YK AYE Sbjct: 1522 LPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYE 1581 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 K KG +G S ++DPKLV NV K+Q+DR YKK Y K K P+DMVS++AAK+ Q Sbjct: 1582 KAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQ 1641 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 +A++ +YR HH++ PD +V +R A +QSD Sbjct: 1642 EVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSD 1677 Score = 355 bits (912), Expect = 3e-98 Identities = 180/396 (45%), Positives = 257/396 (64%), Gaps = 1/396 (0%) Query: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 +Q +NA +S+ +Y++DW +K K +DI+ DAI + AKA+ + S+ YK+ Y K G Sbjct: 794 IQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKSKG 853 Query: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 +G ++ DDPK + ++ AK QSDREY+K YEKSK I+ PLDM+ + QAKK Q + S Sbjct: 854 KMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKSQAIAS 913 Query: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVK 180 D+DY++ LH ++ PD +V AKKAY LQSD YK+D W+KG GW+P GS+E+ + K Sbjct: 914 DVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLEMEKAK 973 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A ++LNE+ YR P+ LKFTSI D P +Q+KIN Q S+ Y+ E+ N+P D Sbjct: 974 RASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPD 1033 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 P +Q+K+NA IS Y+ +D+ GYDLR DAI I+ AKA+R ASD YK YE Sbjct: 1034 LPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYE 1093 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 K KG +G +S ++DPKLV NV K+Q+DR YKK Y K+K + P DM ++ AAK+ Q Sbjct: 1094 KAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQ 1153 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 + S+V+Y+H LHH++ PD D+ ++ +QSD Sbjct: 1154 DVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSD 1189 Score = 332 bits (850), Expect = 5e-91 Identities = 174/386 (45%), Positives = 239/386 (61%), Gaps = 6/386 (1%) Query: 15 LYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPK 74 LY++ W K GY + DA+ HA ++ SE KYK + KQ GH++G T++DDPK Sbjct: 4213 LYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPK 4272 Query: 75 SVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTC 134 VW HA +IQ++R YK+ Y K+K N P DM+S++ AK+ Q LVSDIDYRNYLHQW C Sbjct: 4273 LVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMC 4332 Query: 135 LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIK 194 PDQNDVIQA+KAYDLQSDN+Y++DLEWL+GIGW+P SV+ +RV Q ++++ Y K Sbjct: 4333 HPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKNQEMMSQIKY--K 4390 Query: 195 PEALK----FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKIN 250 AL+ F S+VD PE++ AKIN+V S+ Y+ + K K DTP + SK Sbjct: 4391 KNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDM 4450 Query: 251 ALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCR 310 S Y+ AWE K GY L I I AK + + S+ YK YEKQKGHY+ + Sbjct: 4451 GKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGK 4510 Query: 311 SAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYRH 370 E P +V + KM++ Y+K Y D KA + IP DM++ AK Q + SD++YRH Sbjct: 4511 VIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRH 4570 Query: 371 YLHHWSCFPDQNDVIQARKAYDLQSD 396 Y H W+ ++ +VI+ R A ++ SD Sbjct: 4571 YFHQWTSLLEEPNVIRVRNAQEILSD 4596 Score = 261 bits (668), Expect = 6e-70 Identities = 142/400 (35%), Positives = 222/400 (55%), Gaps = 4/400 (1%) Query: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 +Q +NA +S+ LY++DW +K K +DI+ DAI + AKA+ + S+ YK+ Y K G Sbjct: 547 IQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKG 606 Query: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTPLDMMSIVQAKKCQ 117 +G ++ DDPK + ++ AK QSDR YK+ YEK+K TP + + Sbjct: 607 KMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSE 666 Query: 118 VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVM 177 D+ ++ L + + K SD YK++ E KG + P+ + Sbjct: 667 ARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEY 726 Query: 178 RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNV 237 + + Y++ P+ KFT++ D+P ++QA++N Q+S+ Y+ E EK ++ Sbjct: 727 EAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHI 786 Query: 238 PADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKT 297 PAD P +Q ++NA +S+ Y+Q WE K +D++ DAI + AKA+ SD +YK Sbjct: 787 PADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKK 846 Query: 298 AYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAK 357 YEK KG IG S +DPK++ + K Q+DR Y+K Y K + P+DM+ ++ AK Sbjct: 847 DYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAK 906 Query: 358 EGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 + QA+ASDVDY+H LH +S PD +V A+KAY LQSDV Sbjct: 907 KSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDV 946 Score = 241 bits (615), Expect = 9e-64 Identities = 136/388 (35%), Positives = 205/388 (52%), Gaps = 2/388 (0%) Query: 12 SNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQD 71 S LY+ W TK GY + I I AK + + SE KYKE Y KQ GH++ + + + Sbjct: 4455 STILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGE 4514 Query: 72 DPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ 131 P V + K++S Y+K YE +K + P DMM+ V AK+CQ ++SD++YR+Y HQ Sbjct: 4515 FPGVVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQ 4574 Query: 132 WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLY 191 WT L ++ +VI+ + A ++ SDN+YK DL WLKGIG + +++ K + +L ++ Y Sbjct: 4575 WTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQY 4634 Query: 192 RI--KPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKI 249 K + + DTP + A + + SE Y+ + + K +T +++ Sbjct: 4635 TAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRN 4694 Query: 250 NALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGC 309 S+ Y++AW+ VK T Y L + + + HAK + +AS Y+ YEK K Y Sbjct: 4695 LKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLP 4754 Query: 310 RSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYR 369 RS +DP V K+ DRLY+ Y +K KI I DMV + AK+ Q S++DYR Sbjct: 4755 RSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYR 4814 Query: 370 HYLHHWSCFPDQNDVIQARKAYDLQSDV 397 LH W C PD RK D SD+ Sbjct: 4815 LRLHEWICHPDLQVNDHVRKVTDQISDI 4842 Score = 182 bits (461), Expect = 6e-46 Identities = 124/403 (30%), Positives = 190/403 (47%), Gaps = 14/403 (3%) Query: 12 SNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQD 71 S+ LY++ W+ K Y + + + + HAK + +AS KY+E Y K + R++ D Sbjct: 4700 SSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDD 4759 Query: 72 DPKSVWAIHAAKIQSDREYKKAYEKSK-GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH 130 DP + + K+ DR Y+ YEK+K IH P DM+ +V AK Q VS+IDYR LH Sbjct: 4760 DPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVP-DMVEMVTAKDSQKKVSEIDYRLRLH 4818 Query: 131 QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERL 190 +W C PD +K D SD +YK DL WLKGIG + E++ K+A +L ++ Sbjct: 4819 EWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIK 4878 Query: 191 YRIKPEALK----FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQ 246 Y K LK + + DTP +QA + Q+S+ +Y + P + L Sbjct: 4879 Y--KAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLD 4936 Query: 247 SKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHY 306 ++A ++ + + TGY L D +H K +R ++S + YK AYE K + Sbjct: 4937 RALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAY- 4995 Query: 307 IGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDV 366 G +D V V + ++RLY++ Y+ K KI D I K+ Q S++ Sbjct: 4996 -GYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSEL 5054 Query: 367 DYRHYLH----HWSCFPDQNDVIQARKAYDLQSDVSVSPRKQV 405 Y+ H P VI R D+ SD+ QV Sbjct: 5055 IYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQV 5097 Score = 177 bits (448), Expect = 2e-44 Identities = 110/346 (31%), Positives = 175/346 (50%), Gaps = 6/346 (1%) Query: 4 AHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH- 62 A +NA IS + YQ+D+ + K + Y ++ + E K K + AS+ KYKE Y K G Sbjct: 300 ARMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKA 359 Query: 63 HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIH----NTP-LDMMSIVQAKKCQ 117 ++P+ A SD+ YK+ YEK+K TP + +++Q Sbjct: 360 DYNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSD 419 Query: 118 VLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVM 177 D ++ L + + K SD YK++ E +G G+ P+ + Sbjct: 420 KKYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEY 479 Query: 178 RVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNV 237 + + Y++ P+ KFT + D+P ++QA++N+ Q+S+ Y+ E EK ++ Sbjct: 480 EAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHI 539 Query: 238 PADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKT 297 P DTP +Q K+NA +S+ Y+Q WE K +D++ DAI + AKA+ SD +YK Sbjct: 540 PPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKK 599 Query: 298 AYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAK 343 YEK KG IG S +DPK++ + V K Q+DRLYK+ Y KAK Sbjct: 600 DYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAK 645 Score = 133 bits (335), Expect = 3e-31 Identities = 119/409 (29%), Positives = 183/409 (44%), Gaps = 30/409 (7%) Query: 5 HINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYR--KQLGH 62 H LQ SN LY+ T GY + D KH K +R ++S +KYKE Y K G+ Sbjct: 4940 HAYKLQSSN-LYKTSLR-TLPTGYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGY 4997 Query: 63 HMGFRTLQDDPKSVWAIHAAKIQ---SDREYKKAYEKSKG-IHNTPLDMMSIVQAKKCQV 118 +G PK V +H ++ S+R Y++ Y K K IH TP D I Q KK Q Sbjct: 4998 TLG-------PKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTP-DTPEIRQVKKTQE 5049 Query: 119 LVSDIDYRNYLHQWT----CLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSV 174 VS++ Y++ + LP VI + D+ SD YK DL+ LKG G + Sbjct: 5050 AVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTP 5109 Query: 175 EVMRVKNAQNLLNERLYRIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEK 232 +++R ++ + L + LY K + K+ ++DTPE + + +SE +YR A +K+K Sbjct: 5110 DMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQK 5169 Query: 233 ANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASD 292 + DTP +L++K S Y + + + ++HAK +D+ S+ Sbjct: 5170 SIFTSVPDTPDLLRAKRGQKLQSQYLYVEL-ATKERPHHHAGNQTTALKHAKDVKDMVSE 5228 Query: 293 YLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVS 352 YK YEK K Y + P L+ A +D YK+ + K K D + Sbjct: 5229 KKYKIQYEKMKDKY---TPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALD 5285 Query: 353 ISAAKEGQALASDVDYRH----YLHHWSCFPDQNDVIQARKAYDLQSDV 397 I ++ S + Y+ L W PD+ + R D SDV Sbjct: 5286 IVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDV 5334 Score = 126 bits (317), Expect = 3e-29 Identities = 111/401 (27%), Positives = 162/401 (40%), Gaps = 78/401 (19%) Query: 37 IKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 96 +KHAK +++ SE KYK Y K + + D P + A A SD YK+ ++K Sbjct: 5216 LKHAKDVKDMVSEKKYKIQYEKMKDK---YTPVPDTPILIRAKRAYWNASDLRYKETFQK 5272 Query: 97 SKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYLHQ---WTCLPDQNDVIQAKKAYDLQS 152 +KG ++T D + IV +K +S I Y+ NY+ Q W +PD+ + + D S Sbjct: 5273 TKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVS 5332 Query: 153 DNLYKSDLEWLKGIGWLPEGSVEVM----------------------------------- 177 D YK DL WLKGIG + + Sbjct: 5333 DVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPINR 5392 Query: 178 RVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANV 235 K A L+NE+ YR E K + +VD P + AK QIS+ YR +EK K Sbjct: 5393 HFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKF 5452 Query: 236 NVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLY 295 DTP L++ QIS+ Y+ + K GY D + H + +D SD Y Sbjct: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKY 5512 Query: 296 KTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISA 355 K Y++ K + C + + A + K+ + YKK Y +KA Sbjct: 5513 KEVYQRNKSN---CTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKA------------- 5556 Query: 356 AKEGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 HW PD+ D +QA K+ QSD Sbjct: 5557 ------------------HWKWTPDRPDFLQAAKSSLQQSD 5579 Score = 101 bits (252), Expect = 1e-21 Identities = 102/381 (26%), Positives = 175/381 (45%), Gaps = 30/381 (7%) Query: 6 INALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHM- 64 +N Q+++ K + + Y D +E H K + E+ S KYKE Y K+ G M Sbjct: 5856 LNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPML 5915 Query: 65 GFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKS-KGIHNTPLDMM-SIVQAKKCQVLVSD 122 F T P + A + ++QS +EY+K YE+S KG + T L++ +++ K + S+ Sbjct: 5916 DFET----PTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASE 5971 Query: 123 IDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWL---KGIGWLPEGS 173 +YR L + T + D D+++AK A + ++ YK DLE +G+ + + Sbjct: 5972 KEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANET 6031 Query: 174 VEVMRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKE 231 + MR +NA ++ ++ Y+ E K FTS+VDTPE+I A+ S+ Y+ EK Sbjct: 6032 PDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKS 6091 Query: 232 KANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIAS 291 + DTP + + + N S +YQ ++ K + D I K ++ S Sbjct: 6092 MSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSK-GKITVVQDTPEILRVKENQKNFS 6150 Query: 292 DYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMV 351 LYK + G IG + P+++ +K D + Y + + + D+ Sbjct: 6151 SVLYKE--DVSPGTAIG-----KTPEMM----RVKQTQDHISSVKYKEAIGQGTPIPDLP 6199 Query: 352 SISAAKEGQALASDVDYRHYL 372 + KE Q S V Y+ L Sbjct: 6200 EVKRVKETQKHISSVMYKENL 6220 Score = 95.5 bits (236), Expect = 8e-20 Identities = 91/376 (24%), Positives = 173/376 (46%), Gaps = 28/376 (7%) Query: 10 QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69 QIS+ LY+ ++N K +GY D + H + ++ S+ KYKE Y++ + T+ Sbjct: 5470 QISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSN----CTI 5525 Query: 70 QDDPKSVWAI-HAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY--- 125 + D + A A K+ ++ +YKK YE +K D +QA K + SD +Y Sbjct: 5526 EPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLD 5585 Query: 126 RNYLH--QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQ 183 R +L + + D+N V+ + ++SD YK +G + +++ K Sbjct: 5586 REFLKGCKLSVTDDKNTVLALRNTL-IESDLKYKEKHVKERGTCHAVPDTPQILLAKTVS 5644 Query: 184 NLLNERLYR--IKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAW--EKEKANVNV 237 NL++E Y+ +K + +T++ +T + + K +S+ Y+ + EK K+N ++ Sbjct: 5645 NLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSI 5704 Query: 238 PADTPLMLQSKINALQISNKRYQQAW-EDVKMT-GYDLRADAIGIQHAKASRDIASDYLY 295 + P + +A++++ K+ A+ +D K Y AD I+ A + AS+ Y Sbjct: 5705 MLEPPEVK----HAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEY 5760 Query: 296 KTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKIS--IPVDMVSI 353 + + K+ H + S P + A K+ + Y++ ++ K K P D Sbjct: 5761 RAKHRKEGSHGL---SMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLY 5817 Query: 354 SAAKEGQALASDVDYR 369 K+ LAS+V Y+ Sbjct: 5818 KVMKDANNLASEVKYK 5833 Score = 91.7 bits (226), Expect = 1e-18 Identities = 84/315 (26%), Positives = 143/315 (45%), Gaps = 11/315 (3%) Query: 37 IKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQ-SDREYKKAYE 95 I H++ +++ S KYKE + K G T D + I + Q S+ +Y+ + Sbjct: 86 IAHSQKMQDLFSPNKYKEKFEKTKGQPYASTT---DTPELRRIKKVQDQLSEVKYRMDGD 142 Query: 96 KSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH----QWTCLPDQNDVIQAKKAYDLQ 151 +K I + I AKK VS + Y+ ++ PD +++QA K + Sbjct: 143 VAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMF 202 Query: 152 SDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEV 209 S LY D E K + + S E+ RV AQ L++ Y+ + + +FT + D P++ Sbjct: 203 SKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDI 262 Query: 210 IQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMT 269 AK Q+S+ Y+ +E + + +++NA IS ++YQ+ +E++K Sbjct: 263 EFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQ 322 Query: 270 GYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHY-IGCRSAKEDPKLVWAANVLKMQ 328 Y ++ + + K + AS YK YEK KG A E+P+L Sbjct: 323 IYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDAL 382 Query: 329 NDRLYKKAYNDHKAK 343 +D+LYK+ Y KAK Sbjct: 383 SDKLYKENYEKTKAK 397 Score = 91.7 bits (226), Expect = 1e-18 Identities = 105/408 (25%), Positives = 171/408 (41%), Gaps = 29/408 (7%) Query: 8 ALQISN-KLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGF 66 A Q+ N K Y+ D+ K K Y + D AK + + S+ KY++ Y K F Sbjct: 5397 ATQLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDK---F 5452 Query: 67 RTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK-----GIHNTPLDMMSIVQAKKCQVLVS 121 ++ D P+ + K SD YK Y K+K IH+TP+ ++ +K + VS Sbjct: 5453 TSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPM----LLHVRKVKDEVS 5508 Query: 122 DIDYRNYLHQ----WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-IGWLPEGSVEV 176 D+ Y+ + T PD + AK AY + ++ YK E K W P+ + Sbjct: 5509 DLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPD-RPDF 5567 Query: 177 MRVKNAQNLLNERLYRIKPEALK--FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKAN 234 ++ + ++ Y++ E LK S+ D + A N + S+ Y+ KE+ Sbjct: 5568 LQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGT 5627 Query: 235 VNVPADTPLMLQSK-INALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDY 293 + DTP +L +K ++ L NK + + Y + H K SD Sbjct: 5628 CHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT 5687 Query: 294 LYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSI 353 YK + K+KG E P++ A V K Q+D Y+K ++ ++ D I Sbjct: 5688 NYKKKFVKEKGK-SNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTV-ADRPDI 5745 Query: 354 SAAKEGQALASDVDYRHYLH----HWSCFPDQNDVIQARKAYDLQSDV 397 A + AS+V+YR H + D+ A+KA L S V Sbjct: 5746 KKATQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQV 5793 Score = 85.1 bits (209), Expect = 1e-16 Identities = 95/415 (22%), Positives = 167/415 (40%), Gaps = 55/415 (13%) Query: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 ++A +A +++ L K + + + D + A S S+++YK G Sbjct: 5532 IKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKG 5591 Query: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 + ++ DD +V A+ I+SD +YK+ + K +G + D I+ AK LVS Sbjct: 5592 CKL---SVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVS 5648 Query: 122 DIDYRNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG-----IGWLP 170 + Y++++ + +T LP+ D + K+ SD YK KG I P Sbjct: 5649 ENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEP 5708 Query: 171 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEK 230 M V Q+ + R + E L +T++ D P++ +A A Q SE YR K Sbjct: 5709 PEVKHAMEVAKKQSDVAYR--KDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRK 5766 Query: 231 EKANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTG----------YDLRADAIGI 280 E ++ P + +K A S +Y++ ++ K Y + DA + Sbjct: 5767 EGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKDANNL 5826 Query: 281 --------------------------QHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKE 314 H + +AS Y YK YEK KGHY + + Sbjct: 5827 ASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHY---HTIPD 5883 Query: 315 DPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYR 369 + + + ++Q+ YK+ Y + K + + + AKE Q + S +YR Sbjct: 5884 NLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYR 5938 Score = 79.0 bits (193), Expect = 7e-15 Identities = 91/349 (26%), Positives = 140/349 (40%), Gaps = 53/349 (15%) Query: 10 QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYR--KQLGHHMGFR 67 Q+S LY+++W DTK K Y + DA E+ A + + S+ Y E + K L F Sbjct: 166 QVSKVLYKQNWEDTKDK-YLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSL-----FY 219 Query: 68 TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRN 127 D P+ A K SD YKK + + Sbjct: 220 PYNDSPELRRVAQAQKALSDVAYKKGLAEQQA---------------------------- 251 Query: 128 YLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLPEGSVEVMRVKNAQNLL 186 Q+T L D D+ AKK + S YK D E +KG W EV + + + Sbjct: 252 ---QFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKG-KWSETPCFEVANARMNADNI 307 Query: 187 NERLYRIKPEALK---FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKA----NVNVPA 239 + R Y+ E +K + +TPE K V S+ Y+ +EK K NV + Sbjct: 308 STRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPAS 367 Query: 240 DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAY 299 + P + Q K +S+K Y++ +E K + + + ++ +SD YK +Y Sbjct: 368 ENPQLRQLKAAGDALSDKLYKENYEKTKAKSINY-CETPKFKLDTVLQNFSSDKKYKDSY 426 Query: 300 EKQ-KGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIP 347 K GHY+G + EDP V +D+ YK Y + + K P Sbjct: 427 LKDILGHYVG---SFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFP 472 Score = 69.7 bits (169), Expect = 5e-12 Identities = 100/419 (23%), Positives = 165/419 (39%), Gaps = 62/419 (14%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 ++QA N S KLY +DW K Y D+ E++ +++ S+ YK+G +Q Sbjct: 192 LVQAVKNTAMFSKKLYTEDWEADKSLFYPYN-DSPELRRVAQAQKALSDVAYKKGLAEQQ 250 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYE-KSKG-IHNTPLDMMSIVQAKKCQV 118 F L D P +A S ++YK+ YE K KG TP + ++ Sbjct: 251 AQ---FTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETP-----CFEVANARM 302 Query: 119 LVSDIDYRNYLHQWTCLPDQNDVIQA--------KKAYDLQSDNLYKSDLEWLKG---IG 167 +I R Y + + DQ +Q KKA S YK D E KG Sbjct: 303 NADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYN 362 Query: 168 WLPEG-SVEVMRVKNAQNLLNERLYRIKPEALKFTSI--VDTPEVIQAKINAVQISEPLY 224 LP + ++ ++K A + L+++LY+ E K SI +TP+ + S+ Y Sbjct: 363 VLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKY 422 Query: 225 RNAWEKEKANVNVPA-DTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLR--------- 274 ++++ K+ V + + P Q S+K Y+ +E+ + G+ + Sbjct: 423 KDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAI 482 Query: 275 -----------------------ADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRS 311 D+ + A+ + SD YK +E +K C Sbjct: 483 KKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEK---FKCHI 539 Query: 312 AKEDPKLVWAANVLKMQNDRLYKKAYNDHKA-KISIPVDMVSISAAKEGQALASDVDYR 369 + P + +D LYK+ + KA K I VD + + AAK SDV Y+ Sbjct: 540 PPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYK 598 Score = 40.0 bits (92), Expect = 0.004 Identities = 52/226 (23%), Positives = 91/226 (40%), Gaps = 14/226 (6%) Query: 36 EIKHAKASREIASEYKYKEGYRKQLGHHMGFRT-LQDDPKSVWAIHAAKIQSDREYKKAY 94 E++ K ++E S YKE +MG T L P+ H + S YK+ Sbjct: 6262 EMERVKRNQENFSSVLYKE--------NMGKGTPLAVTPEMERVKHNQENISSVLYKENV 6313 Query: 95 EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDN 154 K+ TP + + K+ Q +S + Y+ L + T P ++ + K+ + S Sbjct: 6314 GKATATPVTP----EMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVKRNQENFSSV 6369 Query: 155 LYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKI 214 LYK ++ PE +N ++L +R + + K ++DTPE+ + + Sbjct: 6370 LYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQG-KAAYVLDTPEMRRVRE 6428 Query: 215 NAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQ 260 IS Y +EK K P+ + K N S+ Y+ Sbjct: 6429 TQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYR 6474 Score = 34.7 bits (78), Expect = 0.16 Identities = 37/162 (22%), Positives = 64/162 (39%), Gaps = 10/162 (6%) Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 TP + S+ S +Y++ +E K Y D ++ K +D S+ Y+ + Sbjct: 83 TPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGD 142 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 K C ++ + A V + + LYK+ + D K K +P D + A + Sbjct: 143 VAKTI---CHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNT 199 Query: 361 ALASDVDYRHYLHHW----SCFPDQNDVIQARKAYDLQSDVS 398 A+ S + Y W S F ND + R+ Q +S Sbjct: 200 AMFSK---KLYTEDWEADKSLFYPYNDSPELRRVAQAQKALS 238 >gi|239752495 PREDICTED: similar to nebulin [Homo sapiens] Length = 237 Score = 357 bits (915), Expect = 1e-98 Identities = 177/188 (94%), Positives = 178/188 (94%), Gaps = 6/188 (3%) Query: 50 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 109 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 110 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 169 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142 Query: 170 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWE 229 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE E Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV------E 196 Query: 230 KEKANVNV 237 K + N NV Sbjct: 197 KSRDNFNV 204 Score = 136 bits (342), Expect = 4e-32 Identities = 62/104 (59%), Positives = 78/104 (75%) Query: 293 YLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVS 352 Y YK Y KQ GH++G R+ ++DPK VWA + K+Q+DR YKKAY K + P+DM+S Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 353 ISAAKEGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 I AK+ Q L SD+DYR+YLH W+C PDQNDVIQA+KAYDLQSD Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSD 126 Score = 45.4 bits (106), Expect = 9e-05 Identities = 50/194 (25%), Positives = 89/194 (45%), Gaps = 15/194 (7%) Query: 200 FTSIVDTPEVIQAKINAVQI-SEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKR 258 F ++ D P+ + A I+A +I S+ Y+ A+EK K N P D ++Q+K + +S+ Sbjct: 39 FRTLQDDPKSVWA-IHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDID 97 Query: 259 YQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKEDPKL 318 Y+ + + D + AK + D+ SD LYK+ E KG IG + ++ Sbjct: 98 YRN-----YLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKG--IGW-LPEGSVEV 149 Query: 319 VWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDY---RHYLHHW 375 + N + N+RLY+ K + VD + AK S+V+ + H+ Sbjct: 150 MRVKNAQNLLNERLYR--IKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHY 207 Query: 376 SCFPDQNDVIQARK 389 + DQ + A++ Sbjct: 208 GSYLDQKQLGPAQQ 221 Score = 41.2 bits (95), Expect = 0.002 Identities = 46/162 (28%), Positives = 75/162 (46%), Gaps = 11/162 (6%) Query: 135 LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIK 194 L D + A A +QSD YK E KGI P + +++ K Q L+++ YR Sbjct: 42 LQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY 101 Query: 195 PEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQI 254 ++T + D +VIQAK S+ LY++ E K +P + +++ K NA + Sbjct: 102 LH--QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK-NAQNL 158 Query: 255 SNKR-YQQAWEDVKMTG-------YDLRADAIGIQHAKASRD 288 N+R Y+ E +K T + +A+ I + SRD Sbjct: 159 LNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRD 200 >gi|46049092 nebulin-related anchoring protein isoform C [Homo sapiens] Length = 1695 Score = 330 bits (846), Expect = 1e-90 Identities = 167/395 (42%), Positives = 250/395 (63%) Query: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 LQA NA +S KLY+ W + K KG+++R D++ AKA R++ASE KYKE Y + G Sbjct: 737 LQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRG 796 Query: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 +G + +Q D + ++ +K+QS+ EYKK +E +K + LDM+ +V A+K Q L + Sbjct: 797 KLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLAT 856 Query: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181 D+ Y+ H +T LP V AKKAY LQSDN Y++D++W+KG+GW+ GS+ V + K Sbjct: 857 DVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKK 916 Query: 182 AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241 A L++E+ YR P+ALKFTSI DTPE++QA+I+ Q + LYR E K + AD Sbjct: 917 AGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADL 976 Query: 242 PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301 P +L +K+NA+ IS RY+++W ++ GY LR DA+ Q AKAS +I SDY YK A+EK Sbjct: 977 PEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEK 1036 Query: 302 QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361 KG +G RS ++D L + +Q+D YKK + KA+ +P+DM ++ AK+ Q Sbjct: 1037 MKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQT 1096 Query: 362 LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 LAS+ DY+H L ++ + + A+KA+ LQS+ Sbjct: 1097 LASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSE 1131 Score = 300 bits (767), Expect = 2e-81 Identities = 157/396 (39%), Positives = 241/396 (60%), Gaps = 4/396 (1%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 +++A NA S Y++ W TK KG++++ DA+ + AKAS E+AS KYKE Y K Sbjct: 497 LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 556 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 G MG D + + ++ AK+ S+ EYKK +E+SK + P+DM++I AKK Q L Sbjct: 557 GKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 612 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 SD+DYR LH++T LP+ AKKAY LQS+ YK+DL W+KG+GWL EGS+ + + K Sbjct: 613 SDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAK 672 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A L++E+ YR + + LKFTS+ D+ ++ AK + S Y+ E+ + D Sbjct: 673 KAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 732 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 PL LQ++ NA +S K Y+ +WE+ K G++LR D++ AKA RD+AS+ YK YE Sbjct: 733 EPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYE 792 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 + +G IG + + D ++ + + K+Q++ YKK + D K++ + +DMV + A++ Q Sbjct: 793 RSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQ 852 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 LA+DV Y+ HH++ P V A+KAY LQSD Sbjct: 853 HLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSD 888 Score = 298 bits (764), Expect = 5e-81 Identities = 150/397 (37%), Positives = 247/397 (62%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 +L A +NA+ IS Y++ W+ + GY +R DA+ + AKAS EI S+YKYKE + K Sbjct: 979 VLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK 1038 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 G +G R+L+DD +++A +QSD YKK +E SK + PLDM ++V AKK Q L Sbjct: 1039 GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLA 1098 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 S+ DY++ L Q+T L + + AKKA+ LQS+NLY+SDL +++G+ + G++E+ K Sbjct: 1099 SNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRK 1158 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A L++E YR P + K+T++ DTP ++ AK + +E LY+ A E + + Sbjct: 1159 KASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLG 1218 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 P +++K NA +S+ RY+++W +++ GY L +A+ Q A+AS DIASD+LY+ + Sbjct: 1219 LPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFV 1278 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 K++G IG +S ++DP++ + ++Q++ Y++ +A+ +P+DMV + AK Q Sbjct: 1279 KERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQ 1338 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 ALASD DYR H ++ P+ + A+KA+ LQS++ Sbjct: 1339 ALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSEL 1375 Score = 283 bits (724), Expect = 2e-76 Identities = 146/396 (36%), Positives = 241/396 (60%) Query: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 ++A NA +S+ Y++ W + + +GY + +A+ + A+AS +IAS++ Y+ + K+ G Sbjct: 1223 IRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERG 1282 Query: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 +G ++++DDP+ ++QS+ +Y++ S+ + P+DM+ +V AK Q L S Sbjct: 1283 KLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALAS 1342 Query: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181 D DYR H++T LP+ + AKKA+ LQS+ YKSDL +KGIGWL S ++ K Sbjct: 1343 DHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKK 1402 Query: 182 AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241 A L++E YR KP+++KFT++VD+P+++ AK + + +E +YR+ + + D Sbjct: 1403 AGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDH 1462 Query: 242 PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301 P ++++NAL +S+K Y+ +WE + YD R DAI Q A+ASR+IASD+ YK A+ + Sbjct: 1463 PDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLR 1522 Query: 302 QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361 +G IG RS +DP++ NV ++Q+D YKK + +++ D + AK Q Sbjct: 1523 DRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQ 1582 Query: 362 LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 LASDV YR L +C P+Q + A+KA+ LQSDV Sbjct: 1583 LASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDV 1618 Score = 189 bits (481), Expect = 3e-48 Identities = 133/443 (30%), Positives = 224/443 (50%), Gaps = 55/443 (12%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 +L++ A S+ Y +D+ + KG + AK + E+AS+ +Y + Y+K++ Sbjct: 213 LLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEM 272 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQ-AKKCQVL 119 G + + A Q + Y + YE+ +G + P + Q AKK L Sbjct: 273 ---RGMAGPAIGAEGILTRECAD-QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHEL 328 Query: 120 VSDIDYRNYLHQ------WTCLPDQNDVI--QAKKAYDLQSDNLYKSDLE-----WLKGI 166 SDI YR ++ + LP Q++++ QA+ L S+N YK + + +G+ Sbjct: 329 ASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGV 388 Query: 167 GWLPEGSVEVMRVKN-AQNL-------------------------------LNERLYRIK 194 G + ++ M+V + A N+ L + YR Sbjct: 389 G-MDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQS 447 Query: 195 PEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQI 254 + LK++S+ DTP+++QAKINA Q+S YR +EK K N +P D P ++++K NA Sbjct: 448 IDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLF 507 Query: 255 SNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIGCRSAKE 314 S +Y++ WE K G++++ DA+ + AKAS ++AS+ YK YEK KG +G Sbjct: 508 SEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMG----TA 563 Query: 315 DPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVDYRHYLHH 374 D +L+ + + KM ++ YKK + + K + +P+DMV+I AK+ Q LASD+DYR LH Sbjct: 564 DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHE 623 Query: 375 WSCFPDQNDVIQARKAYDLQSDV 397 ++ P+ A+KAY LQS++ Sbjct: 624 YTVLPEDMKTQWAKKAYGLQSEL 646 Score = 165 bits (418), Expect = 6e-41 Identities = 80/187 (42%), Positives = 119/187 (63%) Query: 3 QAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH 62 +A +NAL +S+K+Y+ W T+ YD R DAI + A+ASREIAS+++YKE + + G Sbjct: 1467 RARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGL 1526 Query: 63 HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSD 122 +G+R++ DDP+ ++ ++QSD EYKK + KS+ ++ D ++QAK+ Q L SD Sbjct: 1527 QIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASD 1586 Query: 123 IDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNA 182 + YR L Q TC P+Q + A+KA+ LQSD YKSDL +G+GW P GS +V + A Sbjct: 1587 VHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRA 1646 Query: 183 QNLLNER 189 L N R Sbjct: 1647 AELANAR 1653 Score = 101 bits (252), Expect = 1e-21 Identities = 102/396 (25%), Positives = 183/396 (46%), Gaps = 27/396 (6%) Query: 16 YQKDWNDTKQKG----YDIRA-DAIEIKHAKASREIASEYKYKEGYRKQL-GHHMGFRTL 69 Y++D+N K KG + + A D + +K A++ ++ SE KYKE Y+ + G + G + Sbjct: 334 YRQDFN--KMKGAAHYHSLPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEG---V 388 Query: 70 QDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYL 129 D +++ A+ + S+ YK Y+ +N P + Q V + D +YR + Sbjct: 389 GMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSI 448 Query: 130 H--QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLN 187 +++ + D ++QAK S Y++D E K LP+ ++++ K L + Sbjct: 449 DKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFS 508 Query: 188 ERLYRIKPEALK---FTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLM 244 E Y+ E K F +D ++ AK + S Y+ +EK K AD+ L+ Sbjct: 509 EVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLL 568 Query: 245 LQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKG 304 +I A S Y++ +E+ K T + L D + I+HAK ++ +ASD Y K+ Sbjct: 569 HSLQI-AKMSSEVEYKKGFEESK-TRFHLPMDMVNIRHAKKAQTLASD----LDYRKKLH 622 Query: 305 HYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALAS 364 Y ED K WA +Q++ YK K + +++ AK+ L S Sbjct: 623 EY---TVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS 679 Query: 365 DVDYRHYLHH--WSCFPDQNDVIQARKAYDLQSDVS 398 + +YR + ++ D + + A+K+ +LQS V+ Sbjct: 680 EKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVA 715 Score = 72.0 bits (175), Expect = 9e-13 Identities = 72/339 (21%), Positives = 133/339 (39%), Gaps = 57/339 (16%) Query: 10 QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69 Q+ ++L + + Q + + D + + HAK ++ +AS++ Y+ Y K F L Sbjct: 1304 QLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK-------FTAL 1356 Query: 70 QDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY- 128 +D K WA A +QS+ YK KGI L + AKK L+S+ YR Sbjct: 1357 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKP 1416 Query: 129 ------------------------------------LHQWTCLPDQNDVIQAKKAYDLQS 152 LH++T +PD D +A+ S Sbjct: 1417 DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLS 1476 Query: 153 DNLYKSDLEWLKGIGW------LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDT 206 D +Y++ E + + +P + R + E R + + + S+ D Sbjct: 1477 DKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDD 1536 Query: 207 PEVIQ-AKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWED 265 P + + +Q S+ Y+ + K ++ + D P +LQ+K + S+ Y+Q Sbjct: 1537 PRMKHFLNVGRLQ-SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQ 1595 Query: 266 VKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKG 304 + +G++HA+ + + SD YK+ +G Sbjct: 1596 PTCD-----PEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1629 Score = 58.5 bits (140), Expect = 1e-08 Identities = 72/284 (25%), Positives = 128/284 (45%), Gaps = 54/284 (19%) Query: 135 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 191 LPD V ++A+K+ + Y D E +G G P R K A L ++ Y Sbjct: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193 Query: 192 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA-DTP-LMLQS 247 + + +F+++VDTPE++++K A S+ Y +E+++ + PA TP + Sbjct: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAK 253 Query: 248 KINALQISNKRYQQAWEDVK-MTGYDLRADAI---------------------------- 278 + N L + +QQ ++++ M G + A+ I Sbjct: 254 RANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPA 313 Query: 279 ----GIQHAKASRDIASDYLYKTAYEKQKG--HYIGCRSAKEDPKLVWAANVLKMQNDRL 332 Q+AK + ++ASD Y+ + K KG HY A+++ L A +V K+ ++ Sbjct: 314 MITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSL-PAQDNLVLKQAQSVNKLVSENK 372 Query: 333 YKKAYNDHK--AKISIPVDMVSISAAKEGQALASDV----DYRH 370 YK+ Y +H + +D ++ A K G +LAS+V DY+H Sbjct: 373 YKENYQNHMRGRYEGVGMDRRTLHAMKVG-SLASNVAYKADYKH 415 >gi|46049105 nebulin-related anchoring protein isoform S [Homo sapiens] Length = 1730 Score = 330 bits (846), Expect = 1e-90 Identities = 167/395 (42%), Positives = 250/395 (63%) Query: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 LQA NA +S KLY+ W + K KG+++R D++ AKA R++ASE KYKE Y + G Sbjct: 772 LQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRG 831 Query: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 +G + +Q D + ++ +K+QS+ EYKK +E +K + LDM+ +V A+K Q L + Sbjct: 832 KLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLAT 891 Query: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181 D+ Y+ H +T LP V AKKAY LQSDN Y++D++W+KG+GW+ GS+ V + K Sbjct: 892 DVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKK 951 Query: 182 AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241 A L++E+ YR P+ALKFTSI DTPE++QA+I+ Q + LYR E K + AD Sbjct: 952 AGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADL 1011 Query: 242 PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301 P +L +K+NA+ IS RY+++W ++ GY LR DA+ Q AKAS +I SDY YK A+EK Sbjct: 1012 PEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEK 1071 Query: 302 QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361 KG +G RS ++D L + +Q+D YKK + KA+ +P+DM ++ AK+ Q Sbjct: 1072 MKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQT 1131 Query: 362 LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 LAS+ DY+H L ++ + + A+KA+ LQS+ Sbjct: 1132 LASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSE 1166 Score = 300 bits (767), Expect = 2e-81 Identities = 157/396 (39%), Positives = 241/396 (60%), Gaps = 4/396 (1%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 +++A NA S Y++ W TK KG++++ DA+ + AKAS E+AS KYKE Y K Sbjct: 532 LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 G MG D + + ++ AK+ S+ EYKK +E+SK + P+DM++I AKK Q L Sbjct: 592 GKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 647 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 SD+DYR LH++T LP+ AKKAY LQS+ YK+DL W+KG+GWL EGS+ + + K Sbjct: 648 SDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAK 707 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A L++E+ YR + + LKFTS+ D+ ++ AK + S Y+ E+ + D Sbjct: 708 KAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 767 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 PL LQ++ NA +S K Y+ +WE+ K G++LR D++ AKA RD+AS+ YK YE Sbjct: 768 EPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYE 827 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 + +G IG + + D ++ + + K+Q++ YKK + D K++ + +DMV + A++ Q Sbjct: 828 RSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQ 887 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 LA+DV Y+ HH++ P V A+KAY LQSD Sbjct: 888 HLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSD 923 Score = 298 bits (764), Expect = 5e-81 Identities = 150/397 (37%), Positives = 247/397 (62%) Query: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 +L A +NA+ IS Y++ W+ + GY +R DA+ + AKAS EI S+YKYKE + K Sbjct: 1014 VLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK 1073 Query: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 G +G R+L+DD +++A +QSD YKK +E SK + PLDM ++V AKK Q L Sbjct: 1074 GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLA 1133 Query: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 S+ DY++ L Q+T L + + AKKA+ LQS+NLY+SDL +++G+ + G++E+ K Sbjct: 1134 SNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRK 1193 Query: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 A L++E YR P + K+T++ DTP ++ AK + +E LY+ A E + + Sbjct: 1194 KASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLG 1253 Query: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 P +++K NA +S+ RY+++W +++ GY L +A+ Q A+AS DIASD+LY+ + Sbjct: 1254 LPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFV 1313 Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 K++G IG +S ++DP++ + ++Q++ Y++ +A+ +P+DMV + AK Q Sbjct: 1314 KERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQ 1373 Query: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 ALASD DYR H ++ P+ + A+KA+ LQS++ Sbjct: 1374 ALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSEL 1410 Score = 283 bits (724), Expect = 2e-76 Identities = 146/396 (36%), Positives = 241/396 (60%) Query: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 ++A NA +S+ Y++ W + + +GY + +A+ + A+AS +IAS++ Y+ + K+ G Sbjct: 1258 IRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERG 1317 Query: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 +G ++++DDP+ ++QS+ +Y++ S+ + P+DM+ +V AK Q L S Sbjct: 1318 KLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALAS 1377 Query: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181 D DYR H++T LP+ + AKKA+ LQS+ YKSDL +KGIGWL S ++ K Sbjct: 1378 DHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKK 1437 Query: 182 AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241 A L++E YR KP+++KFT++VD+P+++ AK + + +E +YR+ + + D Sbjct: 1438 AGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDH 1497 Query: 242 PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301 P ++++NAL +S+K Y+ +WE + YD R DAI Q A+ASR+IASD+ YK A+ + Sbjct: 1498 PDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLR 1557 Query: 302 QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361 +G IG RS +DP++ NV ++Q+D YKK + +++ D + AK Q Sbjct: 1558 DRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQ 1617 Query: 362 LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 LASDV YR L +C P+Q + A+KA+ LQSDV Sbjct: 1618 LASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDV 1653 Score = 191 bits (486), Expect = 8e-49 Identities = 125/390 (32%), Positives = 202/390 (51%), Gaps = 14/390 (3%) Query: 16 YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH-HMGFRTLQDDPK 74 Y +++ + + KG ++AK + E+AS+ KY++ + K G H QD+ Sbjct: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLV 357 Query: 75 SVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYLH--- 130 A K+ S+ EYKK E S+G + K SD Y+ NY + Sbjct: 358 LKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMR 417 Query: 131 -QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNL--LN 187 ++ + + A K L S+ YK+D + I + + A L L Sbjct: 418 GRYEGVGMDRRTLHAMKVGSLASNVAYKADYK--HDIVDYNYPATLTPSYQTAMKLVPLK 475 Query: 188 ERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQS 247 + YR + LK++S+ DTP+++QAKINA Q+S YR +EK K N +P D P ++++ Sbjct: 476 DANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKA 535 Query: 248 KINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYI 307 K NA S +Y++ WE K G++++ DA+ + AKAS ++AS+ YK YEK KG + Sbjct: 536 KTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAM 595 Query: 308 GCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVD 367 G D +L+ + + KM ++ YKK + + K + +P+DMV+I AK+ Q LASD+D Sbjct: 596 G----TADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLD 651 Query: 368 YRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 YR LH ++ P+ A+KAY LQS++ Sbjct: 652 YRKKLHEYTVLPEDMKTQWAKKAYGLQSEL 681 Score = 165 bits (418), Expect = 6e-41 Identities = 80/187 (42%), Positives = 119/187 (63%) Query: 3 QAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH 62 +A +NAL +S+K+Y+ W T+ YD R DAI + A+ASREIAS+++YKE + + G Sbjct: 1502 RARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGL 1561 Query: 63 HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSD 122 +G+R++ DDP+ ++ ++QSD EYKK + KS+ ++ D ++QAK+ Q L SD Sbjct: 1562 QIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASD 1621 Query: 123 IDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNA 182 + YR L Q TC P+Q + A+KA+ LQSD YKSDL +G+GW P GS +V + A Sbjct: 1622 VHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRA 1681 Query: 183 QNLLNER 189 L N R Sbjct: 1682 AELANAR 1688 Score = 74.7 bits (182), Expect = 1e-13 Identities = 94/437 (21%), Positives = 183/437 (41%), Gaps = 92/437 (21%) Query: 16 YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKS 75 Y +D+ + KG + AK + ++AS+ +YK G+ +++ F T+ D P+ Sbjct: 157 YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISR---FSTVVDTPEL 213 Query: 76 VWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQ-AKKCQVLVSDIDY-RNYLHQWT 133 + + A++QSD Y + YE+ +G + P + Q AK+ L SD+ Y + Y + Sbjct: 214 LRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMR 273 Query: 134 CL-----------------------PDQND---------------VIQAKKAYDLQSDNL 155 + P++ + AKKA++L SD Sbjct: 274 GMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIK 333 Query: 156 YKSDLEWLKGIGW---LP-EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI--VDTPE- 208 Y+ D +KG LP + ++ + + ++ L++E Y+ E+ + SI +TP+ Sbjct: 334 YRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQF 393 Query: 209 -------------------------------VIQAKINAVQI----SEPLYRNAWEKEKA 233 + + ++A+++ S Y+ ++ + Sbjct: 394 RNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIV 453 Query: 234 NVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDY 293 + N PA Q+ + + + + Y+Q+ + +K Y D I AK + S Sbjct: 454 DYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLK---YSSVTDTPQIVQAKINAQQLSHV 510 Query: 294 LYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAK-ISIPVDMVS 352 Y+ YEK K +Y ++ P+LV A K+ ++ YK+ + K K + +D +S Sbjct: 511 NYRADYEKNKLNY---TLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMS 567 Query: 353 ISAAKEGQALASDVDYR 369 + AAK LAS++ Y+ Sbjct: 568 LLAAKASGELASNIKYK 584 Score = 72.0 bits (175), Expect = 9e-13 Identities = 72/339 (21%), Positives = 133/339 (39%), Gaps = 57/339 (16%) Query: 10 QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69 Q+ ++L + + Q + + D + + HAK ++ +AS++ Y+ Y K F L Sbjct: 1339 QLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK-------FTAL 1391 Query: 70 QDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY- 128 +D K WA A +QS+ YK KGI L + AKK L+S+ YR Sbjct: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKP 1451 Query: 129 ------------------------------------LHQWTCLPDQNDVIQAKKAYDLQS 152 LH++T +PD D +A+ S Sbjct: 1452 DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLS 1511 Query: 153 DNLYKSDLEWLKGIGW------LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDT 206 D +Y++ E + + +P + R + E R + + + S+ D Sbjct: 1512 DKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDD 1571 Query: 207 PEVIQ-AKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWED 265 P + + +Q S+ Y+ + K ++ + D P +LQ+K + S+ Y+Q Sbjct: 1572 PRMKHFLNVGRLQ-SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQ 1630 Query: 266 VKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKG 304 + +G++HA+ + + SD YK+ +G Sbjct: 1631 PTCD-----PEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1664 Score = 52.8 bits (125), Expect = 6e-07 Identities = 67/278 (24%), Positives = 113/278 (40%), Gaps = 59/278 (21%) Query: 135 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 191 LPD V ++A+K+ + Y D E +G G P R K A L ++ Y Sbjct: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193 Query: 192 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA-DTPLMLQSK 248 + + +F+++VDTPE++++K A S+ Y +E+++ + PA TP Sbjct: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITP------ 247 Query: 249 INALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIG 308 Q AK + ++ASD Y Y+K+ G Sbjct: 248 ------------------------------AYQIAKRANELASDVRYHQQYQKEMRGMAG 277 Query: 309 CRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMV-SISAAKEGQALASDVD 367 E A+ Q + Y + Y +H+ K S P + + AK+ LASD+ Sbjct: 278 PAIGAEGILTRECAD----QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIK 333 Query: 368 YRHYLH------HWSCFPDQNDVI--QARKAYDLQSDV 397 YR + H+ P Q++++ QA+ L S+V Sbjct: 334 YRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371 >gi|5453758 nebulette sarcomeric isoform [Homo sapiens] Length = 1014 Score = 91.3 bits (225), Expect = 1e-18 Identities = 103/428 (24%), Positives = 192/428 (44%), Gaps = 35/428 (8%) Query: 6 INALQISNKLYQKDWNDTKQKGYDIRADAIE---IKHAKASREIASEYKYKEGYRKQLGH 62 + A ++S+++ K+ D + K + +E + + + +AS KYK+ + Sbjct: 220 VEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNM--- 276 Query: 63 HMGFRTLQDDPKSVWAIH---AAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVL 119 + D P ++ H A+K+ S REYKK +E++KG+++ D + + K VL Sbjct: 277 ---HDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVL 333 Query: 120 VSDIDYRNYLHQWTCLP-----DQNDVIQAKKAYDLQSDNLYKSDLE-WLKGIGWLP-EG 172 S + Y+ + P + +K+A +QS+ +YK D E +KG L + Sbjct: 334 QSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDK 393 Query: 173 SVEVMRVKNAQNLLNERLYR------IKPEALKFTSIVDTPEVIQAKINAVQISEPLYRN 226 + E + VK NLL E+ Y+ IK + ++ S + ++ +AK + SE Y+ Sbjct: 394 TPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNS--EVLDIQRAKRASEMASEKEYKK 451 Query: 227 AWEK--EKANVNVPADTPLMLQSKINALQISNKRYQQAWE-DVKMTGYDLRADAIGIQHA 283 E + + DT M +K A S K Y++ E ++K G + D + +Q A Sbjct: 452 DLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRA 511 Query: 284 KASRDIASDYLYKTAYEKQ-KGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKA 342 K + ++AS YK E + KG G + + + P ++ A ++ + R YK + Sbjct: 512 KKASEMASQKQYKKDLENEIKGK--GMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLS 569 Query: 343 KISIPVDMVSISAAKEGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDVSVSPR 402 S D I K Q S V Y+ + + D ++ + +K + Q+ SV + Sbjct: 570 NYSTIADTPEIQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKK--NQQNISSVKYK 627 Query: 403 KQVPHCFA 410 +++ H A Sbjct: 628 EEIKHATA 635 Score = 77.0 bits (188), Expect = 3e-14 Identities = 83/349 (23%), Positives = 140/349 (40%), Gaps = 43/349 (12%) Query: 12 SNKLYQKDW-NDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQ 70 S K Y+KD N+ K KG + D +I AK + EI S+ KYK+ K L + + T+ Sbjct: 519 SQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSN---YSTIA 575 Query: 71 DDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLH 130 D P+ I K Y+K G D I + KK Q +S + Y+ + Sbjct: 576 DTPE----IQRIKTTQQNISAVFYKKEVGAGTAVKDSPEIERVKKNQQNISSVKYKEEIK 631 Query: 131 QWTCLPDQNDVIQAKKAYDLQSDNLYKSD----------------------LEWLKGIGW 168 T + D ++ + K+ S+ YK L +K G Sbjct: 632 HATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEIERVRRNQEQLSAVKYKGE 691 Query: 169 LPEGSV-----EVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPL 223 L G+ E+ R K Q ++ YR + + T++ TPE+ + K N IS Sbjct: 692 LQRGTAISDPPELKRAKENQKNISNVYYR--GQLGRATTLSVTPEMERVKKNQENISSVK 749 Query: 224 YRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHA 283 Y ++ K ++ DTP M K IS +Y + +E K G+ D + Sbjct: 750 YTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPVTERV 809 Query: 284 KASRDIASDYLYKTAY------EKQKGHYIGCRSAKEDPKLVWAANVLK 326 + + + SD YK + +++ G + + + DP ++ + L+ Sbjct: 810 RKNTQVVSDAAYKGVHPHIVEMDRRPGIIVDLKVWRTDPGSIFDLDPLE 858 Score = 69.7 bits (169), Expect = 5e-12 Identities = 99/442 (22%), Positives = 179/442 (40%), Gaps = 60/442 (13%) Query: 10 QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69 Q+ +++ K +D KG+ A E K + E+ ++++ YRK + + Sbjct: 119 QLQSEVAYKQKHDAA-KGFSDYAHMKEPPEVKHAMEV-NKHQSNISYRKDVQDTHTYSAE 176 Query: 70 QDDPKSVWAIHAAKIQSDREYKKAY----------------------------------- 94 D P A +KI S+ EYKK Sbjct: 177 LDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFD 236 Query: 95 --EKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQW----TCLPDQNDVIQAKKAY 148 K K H PL+ S Q + L S++ Y+ + + LP+ + KA Sbjct: 237 NEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKAS 296 Query: 149 DLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALK---FTSIVD 205 + S YK E KG+ +VE + K L ++ Y+ + E K V+ Sbjct: 297 KMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVE 356 Query: 206 TPEVIQAKINAVQISEPLYRNAWEKE-KANVNVPAD-TPLMLQSKINALQISNKRYQQAW 263 TP +K SE +Y+ +EKE K ++ D TP L K + K Y++ Sbjct: 357 TPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDL 416 Query: 264 E-DVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK-QKGHYIGCRSAKEDPKLVWA 321 E ++K G +L ++ + IQ AK + ++AS+ YK E KG G ++ + ++ A Sbjct: 417 ENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGK--GMQAGTDTLEMQHA 474 Query: 322 ANVLKMQNDRLYKK-AYNDHKAK-ISIPVDMVSISAAKEGQALASDVDYRHYLHH----- 374 ++ +++ YK+ + K K + + D + + AK+ +AS Y+ L + Sbjct: 475 KKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGK 534 Query: 375 -WSCFPDQNDVIQARKAYDLQS 395 D D+++A++ ++ S Sbjct: 535 GMQVSMDIPDILRAKRTSEIYS 556 Score = 44.3 bits (103), Expect = 2e-04 Identities = 65/321 (20%), Positives = 124/321 (38%), Gaps = 27/321 (8%) Query: 66 FRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDY 125 ++ + +D A ++ SD YK+ ++KSK D + K +S+ Y Sbjct: 30 YKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKY 89 Query: 126 RNYLHQ------WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL-----PEGSV 174 + + + +P D + A + LQS+ YK + KG P Sbjct: 90 KGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVK 149 Query: 175 EVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNA---WEKE 231 M V Q+ ++ R + + +++ +D P++ A + IS Y+ KE Sbjct: 150 HAMEVNKHQSNISYR--KDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKE 207 Query: 232 KANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIAS 291 A + P + SK+++ +++ +D K L ++ + + + +AS Sbjct: 208 PAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPL--ESASFRQNQLAATLAS 265 Query: 292 DYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVL---KMQNDRLYKKAYNDHKAKISIPV 348 + YK + + P L++ +VL KM + R YKK + ++K Sbjct: 266 NVKYKKDIQNMHD------PVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDA 319 Query: 349 DMVSISAAKEGQALASDVDYR 369 D V K L S V Y+ Sbjct: 320 DAVEHLHHKGNAVLQSQVKYK 340 >gi|47087157 nebulette non-muscle isoform [Homo sapiens] Length = 270 Score = 50.1 bits (118), Expect = 4e-06 Identities = 35/124 (28%), Positives = 58/124 (46%), Gaps = 7/124 (5%) Query: 180 KNAQNLLNERLYRIKPEA------LKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKA 233 K A N+ N + Y KP FT++ DTPE ++ K + S+ Y+ +E+ K Sbjct: 36 KMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKG 95 Query: 234 N-VNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASD 292 ++ DTP + + K QISN +Y + +E K G+ D + + + + SD Sbjct: 96 RGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSD 155 Query: 293 YLYK 296 YK Sbjct: 156 AAYK 159 Score = 45.4 bits (106), Expect = 9e-05 Identities = 24/76 (31%), Positives = 40/76 (52%), Gaps = 2/76 (2%) Query: 16 YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKS 75 Y++D+ ++K +G+ I D E++ K ++E S KY E + K G GF + DDP + Sbjct: 86 YKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGR--GFTPVVDDPVT 143 Query: 76 VWAIHAAKIQSDREYK 91 ++ SD YK Sbjct: 144 ERVRKNTQVVSDAAYK 159 Score = 40.0 bits (92), Expect = 0.004 Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 4/98 (4%) Query: 132 WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERL 190 +T + D + ++ K+ +LQS YK D E KG G+ + + E+ R+K Q ++ Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 191 YRIKPEALK---FTSIVDTPEVIQAKINAVQISEPLYR 225 Y E K FT +VD P + + N +S+ Y+ Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 38.5 bits (88), Expect = 0.011 Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 2/103 (1%) Query: 232 KANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIAS 291 K + ADTP L+ K + S +Y++ +E+ K G+ + D +Q K +++ S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 292 DYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYK 334 + Y +EK KG G +DP ++ +D YK Sbjct: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 34.7 bits (78), Expect = 0.16 Identities = 31/130 (23%), Positives = 60/130 (46%), Gaps = 12/130 (9%) Query: 39 HAKASREIASEYKYKEGYRKQL---GHH--MGFRTLQDDPKSVWAIHAAKIQSDREYKKA 93 H + + + YK GY K+ H+ F T+ D P+++ +++QS +YK+ Sbjct: 31 HCEVCKMALNMNNYK-GYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRD 89 Query: 94 YEKSKGI-HNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKA 147 +E+SKG + D + + K+ Q +S++ Y + +T + D + +K Sbjct: 90 FEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKN 149 Query: 148 YDLQSDNLYK 157 + SD YK Sbjct: 150 TQVVSDAAYK 159 >gi|5453710 LIM and SH3 protein 1 [Homo sapiens] Length = 261 Score = 46.6 bits (109), Expect = 4e-05 Identities = 39/135 (28%), Positives = 60/135 (44%), Gaps = 13/135 (9%) Query: 180 KNAQNLLNERLYRIKPEA------LKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKA 233 K N+ N + Y KP FT + DTPE ++ K + S+ Y+ +EK K Sbjct: 36 KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95 Query: 234 -NVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASD 292 +V ADTP + + K QISN +Y + +E +M + G RD Sbjct: 96 KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM------GPSGGEGMEPERRDSQDG 149 Query: 293 YLYKTAYEKQKGHYI 307 Y+ E+Q+ H+I Sbjct: 150 SSYRRPLEQQQPHHI 164 Score = 35.8 bits (81), Expect = 0.072 Identities = 31/129 (24%), Positives = 59/129 (45%), Gaps = 8/129 (6%) Query: 39 HAKASREIASEYKYKEGYRKQL---GHH--MGFRTLQDDPKSVWAIHAAKIQSDREYKKA 93 H + + + YK GY K+ H+ F + D P+++ +++QS YK+ Sbjct: 31 HCETCKMTLNMKNYK-GYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEE 89 Query: 94 YEKSKGI-HNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQS 152 +EK+KG + D + + KK Q +S+I Y + P + ++ ++ D Q Sbjct: 90 FEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRMGPSGGEGMEPERR-DSQD 148 Query: 153 DNLYKSDLE 161 + Y+ LE Sbjct: 149 GSSYRRPLE 157 Score = 32.0 bits (71), Expect = 1.0 Identities = 13/43 (30%), Positives = 25/43 (58%) Query: 16 YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRK 58 Y++++ K KG+ + AD E++ K +++ S KY E + K Sbjct: 86 YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEK 128 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 32.0 bits (71), Expect = 1.0 Identities = 64/366 (17%), Positives = 152/366 (41%), Gaps = 47/366 (12%) Query: 3 QAHINALQISNKLYQKDWNDTKQK----GYDIRADAIEIKHAKASREIASEYKYKEGYRK 58 +A + ++ NK+ + +T K ++ R E++H K E A E + + + + Sbjct: 579 EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLE 638 Query: 59 QLGHHMGFR--TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKC 116 + + + L+ + + A+ + +RE +K + N + S+ + + Sbjct: 639 KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESL-EKENS 697 Query: 117 QVLVSDIDYRNYLHQWTC-------LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 169 Q+ +++ R + C L +N ++++K + L K+ + + + Sbjct: 698 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757 Query: 170 PEG-SVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAW 228 +G +E R++ N+++ +++ E + + +Q + ++IS + Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESE---LQDLEMENQTLQKNLEELKISS---KRLE 811 Query: 229 EKEKANVNVPADTPLMLQSKINALQISNKRYQQAWE--DVKMTGYDLRADAIGIQHAKAS 286 + EK N ++ +T + + K L+ NKR +Q E D + +++ + ++ S Sbjct: 812 QLEKENKSLEQETSQLEKDK-KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLS 870 Query: 287 RDIASDYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISI 346 ++I +YK + C KE L+ +N L K+A D K +++ Sbjct: 871 KEIG---IYKES----------CVRLKE----------LEKENKELVKRATIDIKTLVTL 907 Query: 347 PVDMVS 352 D+VS Sbjct: 908 REDLVS 913 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 32.0 bits (71), Expect = 1.0 Identities = 64/366 (17%), Positives = 152/366 (41%), Gaps = 47/366 (12%) Query: 3 QAHINALQISNKLYQKDWNDTKQK----GYDIRADAIEIKHAKASREIASEYKYKEGYRK 58 +A + ++ NK+ + +T K ++ R E++H K E A E + + + + Sbjct: 579 EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLE 638 Query: 59 QLGHHMGFR--TLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKC 116 + + + L+ + + A+ + +RE +K + N + S+ + + Sbjct: 639 KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESL-EKENS 697 Query: 117 QVLVSDIDYRNYLHQWTC-------LPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 169 Q+ +++ R + C L +N ++++K + L K+ + + + Sbjct: 698 QLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757 Query: 170 PEG-SVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAW 228 +G +E R++ N+++ +++ E + + +Q + ++IS + Sbjct: 758 YQGLDIENQRLQKTLENSNKKIQQLESE---LQDLEMENQTLQKNLEELKISS---KRLE 811 Query: 229 EKEKANVNVPADTPLMLQSKINALQISNKRYQQAWE--DVKMTGYDLRADAIGIQHAKAS 286 + EK N ++ +T + + K L+ NKR +Q E D + +++ + ++ S Sbjct: 812 QLEKENKSLEQETSQLEKDK-KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLS 870 Query: 287 RDIASDYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISI 346 ++I +YK + C KE L+ +N L K+A D K +++ Sbjct: 871 KEIG---IYKES----------CVRLKE----------LEKENKELVKRATIDIKTLVTL 907 Query: 347 PVDMVS 352 D+VS Sbjct: 908 REDLVS 913 >gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] Length = 1844 Score = 30.0 bits (66), Expect = 4.0 Identities = 38/159 (23%), Positives = 60/159 (37%), Gaps = 20/159 (12%) Query: 103 TPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEW 162 TPL+M S V+ KK + V N HQ + +N+ + D + D +D Sbjct: 100 TPLEMFSNVEFKKKRKRV------NLSHQLNNIKTENEAPIEISSDDSKEDYSLNNDFV- 152 Query: 163 LKGIGWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEP 222 E S V+R K +L E + K + TS+ ++ K+N Q + Sbjct: 153 --------ESSTSVLRYKKQVEVLAENIQDTKSQPNTMTSLQNS-----KKVNPKQGTTK 199 Query: 223 LYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQ 261 K K V L L ++N L+ K +Q Sbjct: 200 NDFKKLRKRKCRDVVDLSESLPLAEELNLLKKDGKDTKQ 238 >gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens] Length = 5890 Score = 29.6 bits (65), Expect = 5.2 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Query: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYND--HKAKISIPVDMVSISAAKE 358 K KGHY S E KL + L + RL + ND +K I +P +S+S KE Sbjct: 5831 KSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPEVELSVSTKKE 5890 >gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sapiens] Length = 1710 Score = 29.6 bits (65), Expect = 5.2 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Query: 118 VLVSDIDYRNYL--HQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVE 175 V + DI+ RN + H+WT + + K L + + D +L G+ W G E Sbjct: 560 VYLGDINSRNMIRTHEWT----HHQTKRLKFNILLTTYEILLKDKAFLGGLNWAFIGVDE 615 Query: 176 VMRVKNAQNLLNERLYRIK 194 R+KN +LL + L K Sbjct: 616 AHRLKNDDSLLYKTLIDFK 634 >gi|4885237 forkhead box C2 [Homo sapiens] Length = 501 Score = 28.9 bits (63), Expect = 8.8 Identities = 11/40 (27%), Positives = 25/40 (62%) Query: 335 KAYNDHKAKISIPVDMVSISAAKEGQALASDVDYRHYLHH 374 +A +DH + + P+ ++++A +EG A+ ++H+ HH Sbjct: 356 EALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHH 395 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.130 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,361,125 Number of Sequences: 37866 Number of extensions: 579296 Number of successful extensions: 2100 Number of sequences better than 10.0: 14 Number of HSP's better than 10.0 without gapping: 9 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 1450 Number of HSP's gapped (non-prelim): 92 length of query: 410 length of database: 18,247,518 effective HSP length: 105 effective length of query: 305 effective length of database: 14,271,588 effective search space: 4352834340 effective search space used: 4352834340 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.