Guide to the Human Genome
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Search of human proteins with 112734863

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112734863 methyltransferase like 12 [Homo sapiens]
         (240 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112734863 methyltransferase like 12 [Homo sapiens]                 499   e-142
gi|153945707 endothelin converting enzyme 2 isoform C [Homo sapi...    62   4e-10
gi|42542403 CGI-01 protein isoform 1 [Homo sapiens]                    48   7e-06
gi|55956895 CGI-01 protein isoform 3 [Homo sapiens]                    47   2e-05
gi|153945761 endothelin converting enzyme 2 isoform A [Homo sapi...    42   4e-04
gi|58219056 methyltransferase like 10 [Homo sapiens]                   37   0.012
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa...    29   3.2  
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap...    29   3.2  
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap...    29   3.2  
gi|42542405 CGI-01 protein isoform 2 [Homo sapiens]                    29   4.2  
gi|93588611 angiotensin II receptor-associated protein isoform e...    29   4.2  
gi|93588503 angiotensin II receptor-associated protein isoform d...    29   4.2  
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]        28   7.1  
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]        28   7.1  
gi|17402888 neuronal pentraxin receptor [Homo sapiens]                 28   9.2  
gi|143770880 laminin, beta 4 [Homo sapiens]                            28   9.2  
gi|226817316 SH3 domain containing 20 [Homo sapiens]                   28   9.2  
gi|194328738 hypothetical protein LOC23247 [Homo sapiens]              28   9.2  

>gi|112734863 methyltransferase like 12 [Homo sapiens]
          Length = 240

 Score =  499 bits (1286), Expect = e-142
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MAALRRMLHLPSLMMGTCRPFAGSLADSCLADRCLWDRLHAQPRLGTVPTFDWFFGYDEV 60
           MAALRRMLHLPSLMMGTCRPFAGSLADSCLADRCLWDRLHAQPRLGTVPTFDWFFGYDEV
Sbjct: 1   MAALRRMLHLPSLMMGTCRPFAGSLADSCLADRCLWDRLHAQPRLGTVPTFDWFFGYDEV 60

Query: 61  QGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLL 120
           QGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLL
Sbjct: 61  QGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLL 120

Query: 121 EGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSGSFQLLLDKGTWDAVARGGLPRAYQL 180
           EGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSGSFQLLLDKGTWDAVARGGLPRAYQL
Sbjct: 121 EGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSGSFQLLLDKGTWDAVARGGLPRAYQL 180

Query: 181 LSECLRVLNPQGTLIQFSDEDPDVRLPCLEQGSYGWTVTVQELGPFRGITYFAYLIQGSH 240
           LSECLRVLNPQGTLIQFSDEDPDVRLPCLEQGSYGWTVTVQELGPFRGITYFAYLIQGSH
Sbjct: 181 LSECLRVLNPQGTLIQFSDEDPDVRLPCLEQGSYGWTVTVQELGPFRGITYFAYLIQGSH 240


>gi|153945707 endothelin converting enzyme 2 isoform C [Homo
           sapiens]
          Length = 255

 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 63/211 (29%), Positives = 90/211 (42%), Gaps = 35/211 (16%)

Query: 36  WDRLHAQPRLGTVPTFDWFFGYDEVQGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYT 95
           WD+ + Q    + P +DWF  +   + LL P L+        R+L +GCG S+L   L+ 
Sbjct: 26  WDQRY-QGAADSAP-YDWFGDFSSFRALLEPELRPED-----RILVLGCGNSALSYELFL 78

Query: 96  KSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSG 155
               P +V  VD+S V VA M +     P             L +   D + L     S 
Sbjct: 79  GG-FP-NVTSVDYSSVVVAAMQARHAHVP------------QLRWETMDVRKLDF--PSA 122

Query: 156 SFQLLLDKGTWDAVARG----------GLPRAYQLLSECLRVLNPQGTLIQFSDEDPDVR 205
           SF ++L+KGT DA+  G          G+    Q+LSE  RVL P G  I  +   P  R
Sbjct: 123 SFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVSRVLVPGGRFISMTSAAPHFR 182

Query: 206 LPCLEQGSYGWTVTVQELGPFRGITYFAYLI 236
                Q  YGW++     G   G  +  YL+
Sbjct: 183 TRHYAQAYYGWSLRHATYG--SGFHFHLYLM 211


>gi|42542403 CGI-01 protein isoform 1 [Homo sapiens]
          Length = 699

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 47/178 (26%), Positives = 74/178 (41%), Gaps = 25/178 (14%)

Query: 51  FDWFFGYDEVQGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSP 110
           F+W+  Y E+ G+L   ++  +     +VL +GCG S L   LY       D++ +D S 
Sbjct: 29  FEWYGTYLELCGVLHKYIKPRE-----KVLVIGCGNSELSEQLYDVGYR--DIVNIDISE 81

Query: 111 VAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSGSFQLLLDKGTWDAV- 169
           V +  M             C       + F+  D   +       SFQ++LDKGT DAV 
Sbjct: 82  VVIKQMKE-----------CNATRRPQMSFLKMDMTQMEF--PDASFQVVLDKGTLDAVL 128

Query: 170 ---ARGGLPRAYQLLSECLRVLNPQGTLIQFSDEDPDVRLPCLEQGS-YGWTVTVQEL 223
                  L +  ++L+E  RVL   G  +  S     +    +   S  GW V V ++
Sbjct: 129 TDEEEKTLQQVDRMLAEVGRVLQVGGRYLCISLAQAHILKKAVGHFSREGWMVRVHQV 186


>gi|55956895 CGI-01 protein isoform 3 [Homo sapiens]
          Length = 543

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 41/147 (27%), Positives = 64/147 (43%), Gaps = 24/147 (16%)

Query: 51  FDWFFGYDEVQGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSP 110
           F+W+  Y E+ G+L   ++  +     +VL +GCG S L   LY       D++ +D S 
Sbjct: 29  FEWYGTYLELCGVLHKYIKPRE-----KVLVIGCGNSELSEQLYDVGYR--DIVNIDISE 81

Query: 111 VAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSGSFQLLLDKGTWDAV- 169
           V +  M             C       + F+  D   +       SFQ++LDKGT DAV 
Sbjct: 82  VVIKQMKE-----------CNATRRPQMSFLKMDMTQMEF--PDASFQVVLDKGTLDAVL 128

Query: 170 ---ARGGLPRAYQLLSECLRVLNPQGT 193
                  L +  ++L+E  RVL  + T
Sbjct: 129 TDEEEKTLQQVDRMLAEVGRVLQGRET 155


>gi|153945761 endothelin converting enzyme 2 isoform A [Homo
           sapiens]
          Length = 883

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 42/137 (30%), Positives = 62/137 (45%), Gaps = 23/137 (16%)

Query: 36  WDRLHAQPRLGTVPTFDWFFGYDEVQGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYT 95
           WD+ + Q    + P +DWF  +   + LL P L+        R+L +GCG S+L   L+ 
Sbjct: 26  WDQRY-QGAADSAP-YDWFGDFSSFRALLEPELRPED-----RILVLGCGNSALSYELFL 78

Query: 96  KSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSG 155
               P +V  VD+S V VA M +     P             L +   D + L     S 
Sbjct: 79  GG-FP-NVTSVDYSSVVVAAMQARHAHVP------------QLRWETMDVRKLDF--PSA 122

Query: 156 SFQLLLDKGTWDAVARG 172
           SF ++L+KGT DA+  G
Sbjct: 123 SFDVVLEKGTLDALLAG 139


>gi|58219056 methyltransferase like 10 [Homo sapiens]
          Length = 291

 Score = 37.4 bits (85), Expect = 0.012
 Identities = 50/205 (24%), Positives = 82/205 (40%), Gaps = 25/205 (12%)

Query: 20  PFAGSLADSCLADRCLWDRLHAQPRLGTV----PTFDWFFGYDEVQGLLLPLLQEAQAAS 75
           P       S L  R  WD ++ +  L T      T + +FG +E    L+  +Q+ +   
Sbjct: 22  PGEDGFVPSALGTREHWDAVYER-ELQTFREYGDTGEIWFG-EESMNRLIRWMQKHKIPL 79

Query: 76  PLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPA 135
              VLD+G G       L        ++ G+D+SP A+    S++E              
Sbjct: 80  DASVLDIGTGNGVFLVELAKFGFS--NITGIDYSPSAIQLSGSIIEK----------EGL 127

Query: 136 SSLHFMHADAQNLGAVASSGSFQLLLDKGTWDAVA---RGGLPRAYQLLSECLRVLNPQG 192
           S++     D  NL    S   F + +DKGT+DA++      + +  Q +    RVL  +G
Sbjct: 128 SNIKLKVEDFLNLSTQLSG--FHICIDKGTFDAISLNPDNAIEKRKQYVKSLSRVLKVKG 185

Query: 193 TLIQFSDEDPDVRLPCLEQGSYGWT 217
             +  S       L  L + S GW+
Sbjct: 186 FFLITSCNWTKEEL--LNEFSEGWS 208


>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
           sapiens]
          Length = 817

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 14/34 (41%), Positives = 17/34 (50%)

Query: 121 EGGPGQTPLCPGHPASSLHFMHADAQNLGAVASS 154
           EGG  + PLCPG PA     +   A   GA  S+
Sbjct: 755 EGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSA 788


>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
           sapiens]
          Length = 887

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 14/34 (41%), Positives = 17/34 (50%)

Query: 121 EGGPGQTPLCPGHPASSLHFMHADAQNLGAVASS 154
           EGG  + PLCPG PA     +   A   GA  S+
Sbjct: 824 EGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSA 857


>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sapiens]
          Length = 1152

 Score = 29.3 bits (64), Expect = 3.2
 Identities = 14/34 (41%), Positives = 17/34 (50%)

Query: 121  EGGPGQTPLCPGHPASSLHFMHADAQNLGAVASS 154
            EGG  + PLCPG PA     +   A   GA  S+
Sbjct: 1089 EGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSA 1122


>gi|42542405 CGI-01 protein isoform 2 [Homo sapiens]
          Length = 613

 Score = 28.9 bits (63), Expect = 4.2
 Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 5/73 (6%)

Query: 156 SFQLLLDKGTWDAV----ARGGLPRAYQLLSECLRVLNPQGTLIQFSDEDPDVRLPCLEQ 211
           SFQ++LDKGT DAV        L +  ++L+E  RVL   G  +  S     +    +  
Sbjct: 28  SFQVVLDKGTLDAVLTDEEEKTLQQVDRMLAEVGRVLQVGGRYLCISLAQAHILKKAVGH 87

Query: 212 GS-YGWTVTVQEL 223
            S  GW V V ++
Sbjct: 88  FSREGWMVRVHQV 100


>gi|93588611 angiotensin II receptor-associated protein isoform e
           [Homo sapiens]
          Length = 147

 Score = 28.9 bits (63), Expect = 4.2
 Identities = 35/121 (28%), Positives = 45/121 (37%), Gaps = 31/121 (25%)

Query: 30  LADRCLWDRLHAQPRLGTVPTFDWFFGYDEVQGLLLPLLQEAQAASP-----LRVL---- 80
           L   C W    A+PRL T+          E+   L  L   A  A+      LR+L    
Sbjct: 17  LLTTCFWRHFSAKPRLETI----------ELTCALCKLRSAAHRATAGLHCILRLLCLGQ 66

Query: 81  -------DVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLLEGGP-GQTPLCPG 132
                   VGCG++    GL+ +  H    L     P   AH + L  G P G  PL  G
Sbjct: 67  LHHPGLGRVGCGSA----GLHRRHKHVSGWLAGHHLPGHRAHQHLLPAGQPHGHGPLWRG 122

Query: 133 H 133
           H
Sbjct: 123 H 123


>gi|93588503 angiotensin II receptor-associated protein isoform d
           [Homo sapiens]
          Length = 155

 Score = 28.9 bits (63), Expect = 4.2
 Identities = 35/121 (28%), Positives = 45/121 (37%), Gaps = 31/121 (25%)

Query: 30  LADRCLWDRLHAQPRLGTVPTFDWFFGYDEVQGLLLPLLQEAQAASP-----LRVL---- 80
           L   C W    A+PRL T+          E+   L  L   A  A+      LR+L    
Sbjct: 17  LLTTCFWRHFSAKPRLETI----------ELTCALCKLRSAAHRATAGLHCILRLLCLGQ 66

Query: 81  -------DVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLLEGGP-GQTPLCPG 132
                   VGCG++    GL+ +  H    L     P   AH + L  G P G  PL  G
Sbjct: 67  LHHPGLGRVGCGSA----GLHRRHKHVSGWLAGHHLPGHRAHQHLLPAGQPHGHGPLWRG 122

Query: 133 H 133
           H
Sbjct: 123 H 123


>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 101 VDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSGSFQLL 160
           V  L  + +   VA   S + GG    PL   HPA+ L ++  D+Q+   +AS    +LL
Sbjct: 98  VSFLCANDASYVVAQWASWMSGGVA-VPLYRKHPAAQLEYVICDSQSSVVLASQEYLELL 156


>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
          Length = 576

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 101 VDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSGSFQLL 160
           V  L  + +   VA   S + GG    PL   HPA+ L ++  D+Q+   +AS    +LL
Sbjct: 98  VSFLCANDASYVVAQWASWMSGGVA-VPLYRKHPAAQLEYVICDSQSSVVLASQEYLELL 156


>gi|17402888 neuronal pentraxin receptor [Homo sapiens]
          Length = 500

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 22/67 (32%), Positives = 26/67 (38%), Gaps = 12/67 (17%)

Query: 73  AASPLRVLDVGCGTSSLCTGLYTKSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPG 132
           AASP R L  G   +S+ +G    SP P   L                 GG    P  PG
Sbjct: 29  AASPARALPGGADNASVASGA-AASPGPQRSLSALHGA-----------GGSAGPPALPG 76

Query: 133 HPASSLH 139
            PA+S H
Sbjct: 77  APAASAH 83


>gi|143770880 laminin, beta 4 [Homo sapiens]
          Length = 1761

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 12/27 (44%), Positives = 17/27 (62%)

Query: 122 GGPGQTPLCPGHPASSLHFMHADAQNL 148
           G P +  LCP  P+S+ +F H+  QNL
Sbjct: 905 GQPCRPCLCPDDPSSNQYFAHSCYQNL 931


>gi|226817316 SH3 domain containing 20 [Homo sapiens]
          Length = 263

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 8/80 (10%)

Query: 112 AVAHMNSLLEGGPG---QTPLCPGHPASSLHFMHADAQN--LGAVASSGSFQLLLDKGTW 166
           A    +SL  G P      P  P  PA SL+ +   A +   G + SSGSF+     G+W
Sbjct: 128 AATQRSSLAPGLPACLYLRPAAPVRPAQSLNDLACAAVSPPAGLLGSSGSFKACSVAGSW 187

Query: 167 ---DAVARGGLPRAYQLLSE 183
                +AR      Y+++ +
Sbjct: 188 VCPRPLARSDSENVYEVIQD 207


>gi|194328738 hypothetical protein LOC23247 [Homo sapiens]
          Length = 1618

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 2/60 (3%)

Query: 91  TGLYTKSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTP-LCPGHPASSLHFMHADAQNLG 149
           T LY  SPH VD+            +N  L G    +P  CP HP   L F+  + + LG
Sbjct: 506 TKLYV-SPHDVDIRNTATPGELGRLVNRNLAGKKDSSPWTCPFHPPLQLFFVIRNTRQLG 564


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.448 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,353,464
Number of Sequences: 37866
Number of extensions: 510407
Number of successful extensions: 1017
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1006
Number of HSP's gapped (non-prelim): 18
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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