Guide to the Human Genome
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Search of human proteins with 169209448

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169209448 PREDICTED: hypothetical protein [Homo sapiens]
         (260 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169209448 PREDICTED: hypothetical protein [Homo sapiens]           531   e-151
gi|169210084 PREDICTED: hypothetical protein [Homo sapiens]           530   e-151
gi|169210523 PREDICTED: hypothetical protein [Homo sapiens]           529   e-150
gi|27436893 tapasin isoform 1 precursor [Homo sapiens]                 34   0.15 
gi|27436897 tapasin isoform 3 precursor [Homo sapiens]                 34   0.15 
gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor ...    31   0.95 
gi|239754370 PREDICTED: hypothetical protein [Homo sapiens]            30   2.1  
gi|239748924 PREDICTED: hypothetical protein [Homo sapiens]            30   2.1  
gi|239742946 PREDICTED: hypothetical protein [Homo sapiens]            30   2.1  
gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]          30   2.1  
gi|116325985 transcript expressed during hematopoiesis 2 [Homo s...    29   4.7  
gi|4885377 histone cluster 1, H1d [Homo sapiens]                       29   4.7  
gi|38194229 kelch-like 17 [Homo sapiens]                               29   4.7  
gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor [...    28   6.1  
gi|122937480 Ras association (RalGDS/AF-6) domain family (N-term...    28   6.1  
gi|41281996 HEAT repeat containing 3 [Homo sapiens]                    28   6.1  
gi|21389443 transmembrane protein 125 [Homo sapiens]                   28   6.1  
gi|239751466 PREDICTED: hypothetical protein XP_002347845 [Homo ...    28   8.0  
gi|32964823 antimicrobial peptide RYA3 [Homo sapiens]                  28   8.0  

>gi|169209448 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 260

 Score =  531 bits (1369), Expect = e-151
 Identities = 260/260 (100%), Positives = 260/260 (100%)

Query: 1   MHVLLTGHVNAEVPGHVGLIITHLAPPGGFGFWFGRRGGPAGATDIGCRRRRSHRRRRRP 60
           MHVLLTGHVNAEVPGHVGLIITHLAPPGGFGFWFGRRGGPAGATDIGCRRRRSHRRRRRP
Sbjct: 1   MHVLLTGHVNAEVPGHVGLIITHLAPPGGFGFWFGRRGGPAGATDIGCRRRRSHRRRRRP 60

Query: 61  GSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPG 120
           GSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPG
Sbjct: 61  GSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPG 120

Query: 121 VGLPAFAVDTGAPRLRVLLLHVCLQGLLVLIVPVALGALECLTRVTRMHHGHVAAQRAGG 180
           VGLPAFAVDTGAPRLRVLLLHVCLQGLLVLIVPVALGALECLTRVTRMHHGHVAAQRAGG
Sbjct: 121 VGLPAFAVDTGAPRLRVLLLHVCLQGLLVLIVPVALGALECLTRVTRMHHGHVAAQRAGG 180

Query: 181 AQDRVAFGALHATPRGALPNPKLAEGASVLVMGNEAPIVTLCAFIWFWCCGIVFIGTFVS 240
           AQDRVAFGALHATPRGALPNPKLAEGASVLVMGNEAPIVTLCAFIWFWCCGIVFIGTFVS
Sbjct: 181 AQDRVAFGALHATPRGALPNPKLAEGASVLVMGNEAPIVTLCAFIWFWCCGIVFIGTFVS 240

Query: 241 KVQPPAALCHIGPDALTVKA 260
           KVQPPAALCHIGPDALTVKA
Sbjct: 241 KVQPPAALCHIGPDALTVKA 260


>gi|169210084 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 260

 Score =  530 bits (1365), Expect = e-151
 Identities = 259/260 (99%), Positives = 260/260 (100%)

Query: 1   MHVLLTGHVNAEVPGHVGLIITHLAPPGGFGFWFGRRGGPAGATDIGCRRRRSHRRRRRP 60
           MHVLLTGHVNAEVPGHVGLIITHLAPPGGFGFWFGRRGGPAGATDIGCRRRRSHRRRRRP
Sbjct: 1   MHVLLTGHVNAEVPGHVGLIITHLAPPGGFGFWFGRRGGPAGATDIGCRRRRSHRRRRRP 60

Query: 61  GSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPG 120
           GSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPG
Sbjct: 61  GSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPG 120

Query: 121 VGLPAFAVDTGAPRLRVLLLHVCLQGLLVLIVPVALGALECLTRVTRMHHGHVAAQRAGG 180
           VGLPAFAVDTGAPRLRVLLLHVCLQGLLVLIVPVALGALECLTRVTRMHHGHVAAQRAGG
Sbjct: 121 VGLPAFAVDTGAPRLRVLLLHVCLQGLLVLIVPVALGALECLTRVTRMHHGHVAAQRAGG 180

Query: 181 AQDRVAFGALHATPRGALPNPKLAEGASVLVMGNEAPIVTLCAFIWFWCCGIVFIGTFVS 240
           AQDRVAFGALHATPRGALPNPKLAEGASVLVMGNEAPIVTLCAFIWFWCCGIVFIGTFVS
Sbjct: 181 AQDRVAFGALHATPRGALPNPKLAEGASVLVMGNEAPIVTLCAFIWFWCCGIVFIGTFVS 240

Query: 241 KVQPPAALCHIGPDALTVKA 260
           +VQPPAALCHIGPDALTVKA
Sbjct: 241 EVQPPAALCHIGPDALTVKA 260


>gi|169210523 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 260

 Score =  529 bits (1362), Expect = e-150
 Identities = 259/260 (99%), Positives = 259/260 (99%)

Query: 1   MHVLLTGHVNAEVPGHVGLIITHLAPPGGFGFWFGRRGGPAGATDIGCRRRRSHRRRRRP 60
           MHVLLTGHVNAEVPGHVGLIITHLAPPGGFGFWFG RGGPAGATDIGCRRRRSHRRRRRP
Sbjct: 1   MHVLLTGHVNAEVPGHVGLIITHLAPPGGFGFWFGGRGGPAGATDIGCRRRRSHRRRRRP 60

Query: 61  GSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPG 120
           GSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPG
Sbjct: 61  GSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPG 120

Query: 121 VGLPAFAVDTGAPRLRVLLLHVCLQGLLVLIVPVALGALECLTRVTRMHHGHVAAQRAGG 180
           VGLPAFAVDTGAPRLRVLLLHVCLQGLLVLIVPVALGALECLTRVTRMHHGHVAAQRAGG
Sbjct: 121 VGLPAFAVDTGAPRLRVLLLHVCLQGLLVLIVPVALGALECLTRVTRMHHGHVAAQRAGG 180

Query: 181 AQDRVAFGALHATPRGALPNPKLAEGASVLVMGNEAPIVTLCAFIWFWCCGIVFIGTFVS 240
           AQDRVAFGALHATPRGALPNPKLAEGASVLVMGNEAPIVTLCAFIWFWCCGIVFIGTFVS
Sbjct: 181 AQDRVAFGALHATPRGALPNPKLAEGASVLVMGNEAPIVTLCAFIWFWCCGIVFIGTFVS 240

Query: 241 KVQPPAALCHIGPDALTVKA 260
           KVQPPAALCHIGPDALTVKA
Sbjct: 241 KVQPPAALCHIGPDALTVKA 260


>gi|27436893 tapasin isoform 1 precursor [Homo sapiens]
          Length = 448

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 3/92 (3%)

Query: 12  EVPGHVGLIITHLAPPGGFGFWFGRRGGPAGATD-IGCRRRRSHRRRRRPGSV--AEDLL 68
           E P  +  +++H  P GG    +  RGGP G +     +R  S  R    GSV  +  L 
Sbjct: 308 EAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSVSLSGHLQ 367

Query: 69  PPSILQVLHVVEMLVRLHMNTEVAFGSCGVVT 100
           PP +    H      R+H  +  A G    VT
Sbjct: 368 PPPVTTEQHGARYACRIHHPSLPASGRSAEVT 399


>gi|27436897 tapasin isoform 3 precursor [Homo sapiens]
          Length = 412

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 3/92 (3%)

Query: 12  EVPGHVGLIITHLAPPGGFGFWFGRRGGPAGATD-IGCRRRRSHRRRRRPGSV--AEDLL 68
           E P  +  +++H  P GG    +  RGGP G +     +R  S  R    GSV  +  L 
Sbjct: 308 EAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSVSLSGHLQ 367

Query: 69  PPSILQVLHVVEMLVRLHMNTEVAFGSCGVVT 100
           PP +    H      R+H  +  A G    VT
Sbjct: 368 PPPVTTEQHGARYACRIHHPSLPASGRSAEVT 399


>gi|115511020 Smg-6 homolog, nonsense mediated mRNA decay factor
           [Homo sapiens]
          Length = 1419

 Score = 31.2 bits (69), Expect = 0.95
 Identities = 13/20 (65%), Positives = 14/20 (70%)

Query: 41  AGATDIGCRRRRSHRRRRRP 60
           AG TD GCRRRR  R + RP
Sbjct: 271 AGLTDNGCRRRRQDRTKERP 290


>gi|239754370 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 435

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 37/136 (27%), Positives = 48/136 (35%), Gaps = 33/136 (24%)

Query: 35  GRRGGPAGATDIGCRRRRSHRRRRR------------------PGSVAEDLLPP----SI 72
           GR  G  GA + G RR+ + RR                     PG+ A   LP     + 
Sbjct: 223 GRESGSTGAINQGRRRKDAARRLPNRNLLRDLSLPRGAQSSPLPGARASSFLPAPQHGAP 282

Query: 73  LQVLHVVEMLVRL---------HMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPGVGL 123
           L V HV +   R          H  T  A G    +  L    L   R    +C P   L
Sbjct: 283 LDVAHVPDSGPRAASAPARTPGHARTRAAAGPAAYLRGLMVASLAWVRRHAHTCPP--PL 340

Query: 124 PAFAVDTGAPRLRVLL 139
           PA ++  GA R R+ L
Sbjct: 341 PAASLAAGAERARLNL 356


>gi|239748924 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 435

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 37/136 (27%), Positives = 48/136 (35%), Gaps = 33/136 (24%)

Query: 35  GRRGGPAGATDIGCRRRRSHRRRRR------------------PGSVAEDLLPP----SI 72
           GR  G  GA + G RR+ + RR                     PG+ A   LP     + 
Sbjct: 223 GRESGSTGAINQGRRRKDAARRLPNRNLLRDLSLPRGAQSSPLPGARASSFLPAPQHGAP 282

Query: 73  LQVLHVVEMLVRL---------HMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPGVGL 123
           L V HV +   R          H  T  A G    +  L    L   R    +C P   L
Sbjct: 283 LDVAHVPDSGPRAASAPARTPGHARTRAAAGPAAYLRGLMVASLAWVRRHAHTCPP--PL 340

Query: 124 PAFAVDTGAPRLRVLL 139
           PA ++  GA R R+ L
Sbjct: 341 PAASLAAGAERARLNL 356


>gi|239742946 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 435

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 37/136 (27%), Positives = 48/136 (35%), Gaps = 33/136 (24%)

Query: 35  GRRGGPAGATDIGCRRRRSHRRRRR------------------PGSVAEDLLPP----SI 72
           GR  G  GA + G RR+ + RR                     PG+ A   LP     + 
Sbjct: 223 GRESGSTGAINQGRRRKDAARRLPNRNLLRDLSLPRGAQSSPLPGARASSFLPAPQHGAP 282

Query: 73  LQVLHVVEMLVRL---------HMNTEVAFGSCGVVTHLAAERLVTTRVALASCQPGVGL 123
           L V HV +   R          H  T  A G    +  L    L   R    +C P   L
Sbjct: 283 LDVAHVPDSGPRAASAPARTPGHARTRAAAGPAAYLRGLMVASLAWVRRHAHTCPP--PL 340

Query: 124 PAFAVDTGAPRLRVLL 139
           PA ++  GA R R+ L
Sbjct: 341 PAASLAAGAERARLNL 356


>gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
          Length = 1097

 Score = 30.0 bits (66), Expect = 2.1
 Identities = 22/40 (55%), Positives = 23/40 (57%), Gaps = 6/40 (15%)

Query: 38   GGPAGATD-IGCRRRRSHRRRRR---PGSVAEDLLPPSIL 73
            G P GA D I CR  RSH RRR+   PGSV     PPS L
Sbjct: 1037 GFPGGADDRILCRVGRSHSRRRQGLAPGSVL--CFPPSSL 1074


>gi|116325985 transcript expressed during hematopoiesis 2 [Homo
           sapiens]
          Length = 113

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 2/70 (2%)

Query: 40  PAGATDIGCRRRRSHRRRRRPGSV-AEDLLPPSILQVLHVVEMLVRL-HMNTEVAFGSCG 97
           P GA + GC  R  H RRRR  +V        ++L   +V + +V L H     A+   G
Sbjct: 9   PLGALEQGCPIRVEHDRRRRQFTVRLNGCHDRAVLLYEYVGKRIVDLQHTEVPDAYRGRG 68

Query: 98  VVTHLAAERL 107
           +  HLA   L
Sbjct: 69  IAKHLAKAAL 78


>gi|4885377 histone cluster 1, H1d [Homo sapiens]
          Length = 221

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 25/111 (22%), Positives = 44/111 (39%), Gaps = 8/111 (7%)

Query: 98  VVTHLAAERLVTTRVALASCQPGVGLPAFAVDTGAPRLRVLLLHVCLQGLLVLIVPVALG 157
           ++T   A     + V+LA+ +  +    + V+    R+++ L  +  +G LV        
Sbjct: 44  LITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGAS 103

Query: 158 ALECLTRVTRMHHGHVAAQRAGGAQDRVAFGALHATPRGALPNPKLAEGAS 208
               L +      G   A++AG A+ R         P GA   PK   GA+
Sbjct: 104 GSFKLNKKAASGEGKPKAKKAGAAKPR--------KPAGAAKKPKKVAGAA 146


>gi|38194229 kelch-like 17 [Homo sapiens]
          Length = 642

 Score = 28.9 bits (63), Expect = 4.7
 Identities = 11/24 (45%), Positives = 16/24 (66%)

Query: 96  CGVVTHLAAERLVTTRVALASCQP 119
           C +V H+AA+ +   +V LASC P
Sbjct: 92  CDIVLHVAAKEIRAHKVVLASCSP 115


>gi|55770854 N-methyl-D-aspartate receptor subunit 2C precursor [Homo
            sapiens]
          Length = 1233

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 2/41 (4%)

Query: 2    HVLLTGHVNAEVPGHVGLIITHLAPPGGFGFWFGRRGGPAG 42
            HV L  H +A +P   G +  HL P    G W     GP G
Sbjct: 1148 HVCL--HAHAHLPFCWGAVCPHLPPCASHGSWLSGAWGPLG 1186


>gi|122937480 Ras association (RalGDS/AF-6) domain family
           (N-terminal) member 10 [Homo sapiens]
          Length = 615

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 12/19 (63%), Positives = 13/19 (68%)

Query: 47  GCRRRRSHRRRRRPGSVAE 65
           GCRRRR  RR RR GS  +
Sbjct: 147 GCRRRRRQRRSRRLGSAGD 165


>gi|41281996 HEAT repeat containing 3 [Homo sapiens]
          Length = 680

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 13/44 (29%), Positives = 21/44 (47%)

Query: 53  SHRRRRRPGSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAFGSC 96
           SH+RR R  +   DLLPP+  ++   + +L       E+    C
Sbjct: 331 SHKRRVRRKTFVSDLLPPTDKELRETIALLTAQQTALEIIVNMC 374


>gi|21389443 transmembrane protein 125 [Homo sapiens]
          Length = 219

 Score = 28.5 bits (62), Expect = 6.1
 Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 2/42 (4%)

Query: 142 VCLQGLLVLIVPVALGALECLTRVTRMHHGHVAAQRAGGAQD 183
           +CL  LLVL+  +   A++ +  + + H  HVA  R+GG  D
Sbjct: 74  LCLLALLVLVKQLMSSAVQDMNCIRQAH--HVALLRSGGGAD 113


>gi|239751466 PREDICTED: hypothetical protein XP_002347845 [Homo
          sapiens]
          Length = 80

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 12/28 (42%), Positives = 14/28 (50%)

Query: 6  TGHVNAEVPGHVGLIITHLAPPGGFGFW 33
          TGH +  +P   GL    L  PGG  FW
Sbjct: 36 TGHADGNIPAGPGLCSPQLLLPGGQLFW 63


>gi|32964823 antimicrobial peptide RYA3 [Homo sapiens]
          Length = 476

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 32/92 (34%), Positives = 43/92 (46%), Gaps = 11/92 (11%)

Query: 61  GSVAEDLLPPSILQVLHVVEMLVRLHMNTEVAF---GSCGVVTHLAAERLVTTRVALASC 117
           G   E+L  P +L  L +    V+L ++T+V     G  G +  LAAE  VT+RVALA  
Sbjct: 94  GLKIEELTLPKVLLKL-LPGFGVQLSLHTKVGMHCSGPLGGLLQLAAEVNVTSRVALAVS 152

Query: 118 QPGVGLPAFAVDTGAPRLRVLLLHVCL-QGLL 148
             G  +          R   LL H+ L  GLL
Sbjct: 153 SRGTPILIL------KRCSTLLGHISLFSGLL 178


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.142    0.458 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,284,553
Number of Sequences: 37866
Number of extensions: 517649
Number of successful extensions: 1644
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1635
Number of HSP's gapped (non-prelim): 20
length of query: 260
length of database: 18,247,518
effective HSP length: 100
effective length of query: 160
effective length of database: 14,460,918
effective search space: 2313746880
effective search space used: 2313746880
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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