Guide to the Human Genome
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Search of human proteins with 169194724

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169194724 PREDICTED: similar to FXYD domain-containing ion
transport regulator 6 [Homo sapiens]
         (95 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169194724 PREDICTED: similar to FXYD domain-containing ion tr...   191   1e-49
gi|169194767 PREDICTED: similar to FXYD domain-containing ion tr...   191   1e-49
gi|169190389 PREDICTED: similar to FXYD domain-containing ion tr...   191   1e-49
gi|11612655 FXYD domain-containing ion transport regulator 6 [Ho...   154   1e-38
gi|11612672 phospholemman precursor [Homo sapiens]                     71   2e-13
gi|11612670 phospholemman precursor [Homo sapiens]                     71   2e-13
gi|209862817 FXYD domain containing ion transport regulator 3 is...    63   4e-11
gi|209862809 FXYD domain containing ion transport regulator 3 is...    63   4e-11
gi|5174635 FXYD domain containing ion transport regulator 3 isof...    63   4e-11
gi|11125766 FXYD domain-containing ion transport regulator 2 iso...    52   1e-07
gi|11125764 FXYD domain-containing ion transport regulator 2 iso...    52   1e-07
gi|209862819 FXYD domain containing ion transport regulator 3 is...    51   2e-07
gi|11612674 FXYD domain containing ion transport regulator 3 iso...    51   2e-07
gi|27764904 FXYD domain containing ion transport regulator 4 [Ho...    51   2e-07
gi|209862811 FXYD domain containing ion transport regulator 3 is...    50   4e-07
gi|11612659 FXYD domain-containing ion transport regulator 7 [Ho...    44   4e-05
gi|47778938 FXYD domain-containing ion transport regulator 5 [Ho...    41   2e-04
gi|21618361 FXYD domain-containing ion transport regulator 5 [Ho...    41   2e-04
gi|14917119 keratin 34 [Homo sapiens]                                  28   1.2  
gi|188595665 FXYD domain-containing ion transport regulator 2 is...    28   2.1  
gi|46358066 hypothetical protein LOC388325 [Homo sapiens]              26   6.0  
gi|14270496 protocadherin gamma subfamily B, 3 isoform 2 precurs...    26   6.0  
gi|11128033 protocadherin gamma subfamily B, 3 isoform 1 precurs...    26   6.0  

>gi|169194724 PREDICTED: similar to FXYD domain-containing ion
          transport regulator 6 [Homo sapiens]
          Length = 95

 Score =  191 bits (484), Expect = 1e-49
 Identities = 95/95 (100%), Positives = 95/95 (100%)

Query: 1  MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR 60
          MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR
Sbjct: 1  MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR 60

Query: 61 CKCSFNQKPRTPGEEEAQVENLITANATKLQKAES 95
          CKCSFNQKPRTPGEEEAQVENLITANATKLQKAES
Sbjct: 61 CKCSFNQKPRTPGEEEAQVENLITANATKLQKAES 95


>gi|169194767 PREDICTED: similar to FXYD domain-containing ion
          transport regulator 6 [Homo sapiens]
          Length = 95

 Score =  191 bits (484), Expect = 1e-49
 Identities = 95/95 (100%), Positives = 95/95 (100%)

Query: 1  MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR 60
          MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR
Sbjct: 1  MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR 60

Query: 61 CKCSFNQKPRTPGEEEAQVENLITANATKLQKAES 95
          CKCSFNQKPRTPGEEEAQVENLITANATKLQKAES
Sbjct: 61 CKCSFNQKPRTPGEEEAQVENLITANATKLQKAES 95


>gi|169190389 PREDICTED: similar to FXYD domain-containing ion
          transport regulator 6 [Homo sapiens]
          Length = 95

 Score =  191 bits (484), Expect = 1e-49
 Identities = 95/95 (100%), Positives = 95/95 (100%)

Query: 1  MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR 60
          MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR
Sbjct: 1  MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR 60

Query: 61 CKCSFNQKPRTPGEEEAQVENLITANATKLQKAES 95
          CKCSFNQKPRTPGEEEAQVENLITANATKLQKAES
Sbjct: 61 CKCSFNQKPRTPGEEEAQVENLITANATKLQKAES 95


>gi|11612655 FXYD domain-containing ion transport regulator 6
          [Homo sapiens]
          Length = 95

 Score =  154 bits (389), Expect = 1e-38
 Identities = 76/95 (80%), Positives = 86/95 (90%)

Query: 1  MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR 60
          ME+VL+FLCSLLA +VLA A E+EK++DPFHYDYQTLRI GLV AVVLFS+GILLIL  R
Sbjct: 1  MELVLVFLCSLLAPMVLASAAEKEKEMDPFHYDYQTLRIGGLVFAVVLFSVGILLILSRR 60

Query: 61 CKCSFNQKPRTPGEEEAQVENLITANATKLQKAES 95
          CKCSFNQKPR PG+EEAQVENLITANAT+ QKAE+
Sbjct: 61 CKCSFNQKPRAPGDEEAQVENLITANATEPQKAEN 95


>gi|11612672 phospholemman precursor [Homo sapiens]
          Length = 92

 Score = 71.2 bits (173), Expect = 2e-13
 Identities = 41/88 (46%), Positives = 56/88 (63%), Gaps = 6/88 (6%)

Query: 4  VLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRCKC 63
          +L+F   LL    +A A E  K+ DPF YDYQ+L+I GLV A +LF +GIL++L  RC+C
Sbjct: 7  ILVFCVGLLT---MAKA-ESPKEHDPFTYDYQSLQIGGLVIAGILFILGILIVLSRRCRC 62

Query: 64 SFNQKPRT--PGEEEAQVENLITANATK 89
           FNQ+ RT  P EEE    + I   +T+
Sbjct: 63 KFNQQQRTGEPDEEEGTFRSSIRRLSTR 90


>gi|11612670 phospholemman precursor [Homo sapiens]
          Length = 92

 Score = 71.2 bits (173), Expect = 2e-13
 Identities = 41/88 (46%), Positives = 56/88 (63%), Gaps = 6/88 (6%)

Query: 4  VLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRCKC 63
          +L+F   LL    +A A E  K+ DPF YDYQ+L+I GLV A +LF +GIL++L  RC+C
Sbjct: 7  ILVFCVGLLT---MAKA-ESPKEHDPFTYDYQSLQIGGLVIAGILFILGILIVLSRRCRC 62

Query: 64 SFNQKPRT--PGEEEAQVENLITANATK 89
           FNQ+ RT  P EEE    + I   +T+
Sbjct: 63 KFNQQQRTGEPDEEEGTFRSSIRRLSTR 90


>gi|209862817 FXYD domain containing ion transport regulator 3
          isoform 1 precursor [Homo sapiens]
          Length = 87

 Score = 63.2 bits (152), Expect = 4e-11
 Identities = 30/75 (40%), Positives = 48/75 (64%), Gaps = 1/75 (1%)

Query: 1  MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR 60
          M+ V + L   LA   + DA + E +  PF+YD+ +L++ GL+CA VL ++GI++++  +
Sbjct: 1  MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK 60

Query: 61 CKCSFNQKP-RTPGE 74
          CKC F QK    PGE
Sbjct: 61 CKCKFGQKSGHHPGE 75


>gi|209862809 FXYD domain containing ion transport regulator 3
           isoform 3 [Homo sapiens]
          Length = 144

 Score = 63.2 bits (152), Expect = 4e-11
 Identities = 30/75 (40%), Positives = 48/75 (64%), Gaps = 1/75 (1%)

Query: 1   MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR 60
           M+ V + L   LA   + DA + E +  PF+YD+ +L++ GL+CA VL ++GI++++  +
Sbjct: 58  MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK 117

Query: 61  CKCSFNQKP-RTPGE 74
           CKC F QK    PGE
Sbjct: 118 CKCKFGQKSGHHPGE 132


>gi|5174635 FXYD domain containing ion transport regulator 3
          isoform 1 precursor [Homo sapiens]
          Length = 87

 Score = 63.2 bits (152), Expect = 4e-11
 Identities = 30/75 (40%), Positives = 48/75 (64%), Gaps = 1/75 (1%)

Query: 1  MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCR 60
          M+ V + L   LA   + DA + E +  PF+YD+ +L++ GL+CA VL ++GI++++  +
Sbjct: 1  MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSAK 60

Query: 61 CKCSFNQKP-RTPGE 74
          CKC F QK    PGE
Sbjct: 61 CKCKFGQKSGHHPGE 75


>gi|11125766 FXYD domain-containing ion transport regulator 2
          isoform 1 [Homo sapiens]
          Length = 66

 Score = 51.6 bits (122), Expect = 1e-07
 Identities = 22/50 (44%), Positives = 35/50 (70%)

Query: 27 IDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRCKCSFNQKPRTPGEEE 76
          +DPF+YDY+T+R  GL+ A + F +G+L++L  R +C  N+K R   E+E
Sbjct: 16 VDPFYYDYETVRNGGLIFAGLAFIVGLLILLSRRFRCGGNKKRRQINEDE 65


>gi|11125764 FXYD domain-containing ion transport regulator 2
          isoform 2 [Homo sapiens]
          Length = 64

 Score = 51.6 bits (122), Expect = 1e-07
 Identities = 22/50 (44%), Positives = 35/50 (70%)

Query: 27 IDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRCKCSFNQKPRTPGEEE 76
          +DPF+YDY+T+R  GL+ A + F +G+L++L  R +C  N+K R   E+E
Sbjct: 14 VDPFYYDYETVRNGGLIFAGLAFIVGLLILLSRRFRCGGNKKRRQINEDE 63


>gi|209862819 FXYD domain containing ion transport regulator 3
           isoform 2 precursor [Homo sapiens]
          Length = 113

 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 27/101 (26%)

Query: 1   MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLIL--- 57
           M+ V + L   LA   + DA + E +  PF+YD+ +L++ GL+CA VL ++GI++++   
Sbjct: 1   MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEW 60

Query: 58  -----------------------GCRCKCSFNQKP-RTPGE 74
                                  G +CKC F QK    PGE
Sbjct: 61  RSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGE 101


>gi|11612674 FXYD domain containing ion transport regulator 3
           isoform 2 precursor [Homo sapiens]
          Length = 113

 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 31/101 (30%), Positives = 49/101 (48%), Gaps = 27/101 (26%)

Query: 1   MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLIL--- 57
           M+ V + L   LA   + DA + E +  PF+YD+ +L++ GL+CA VL ++GI++++   
Sbjct: 1   MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEW 60

Query: 58  -----------------------GCRCKCSFNQKP-RTPGE 74
                                  G +CKC F QK    PGE
Sbjct: 61  RSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQKSGHHPGE 101


>gi|27764904 FXYD domain containing ion transport regulator 4
          [Homo sapiens]
          Length = 89

 Score = 51.2 bits (121), Expect = 2e-07
 Identities = 21/50 (42%), Positives = 33/50 (66%)

Query: 28 DPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRCKCSFNQKPRTPGEEEA 77
          DPF+YD++ L++ GL+C  +L   GI  +L  +CKC  +QK  +P  E+A
Sbjct: 28 DPFYYDWKNLQLSGLICGGLLAIAGIAAVLSGKCKCKSSQKQHSPVPEKA 77


>gi|209862811 FXYD domain containing ion transport regulator 3
          isoform4 precursor [Homo sapiens]
          Length = 96

 Score = 50.1 bits (118), Expect = 4e-07
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 26/94 (27%)

Query: 1  MEVVLIFLCSLLAHIVLADAVEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLIL--- 57
          M+ V + L   LA   + DA + E +  PF+YD+ +L++ GL+CA VL ++GI++++   
Sbjct: 1  MQKVTLGLLVFLAGFPVLDANDLEDKNSPFYYDWHSLQVGGLICAGVLCAMGIIIVMSEW 60

Query: 58 -----------------------GCRCKCSFNQK 68
                                 G +CKC F QK
Sbjct: 61 RSSGEQAGRGWGSPPLTTQLSPTGAKCKCKFGQK 94


>gi|11612659 FXYD domain-containing ion transport regulator 7
          [Homo sapiens]
          Length = 80

 Score = 43.5 bits (101), Expect = 4e-05
 Identities = 16/36 (44%), Positives = 26/36 (72%)

Query: 28 DPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRCKC 63
          DPF+YDY T++  G+  A +LF +GIL+++  + KC
Sbjct: 16 DPFYYDYNTVQTVGMTLATILFLLGILIVISKKVKC 51


>gi|47778938 FXYD domain-containing ion transport regulator 5 [Homo
           sapiens]
          Length = 178

 Score = 41.2 bits (95), Expect = 2e-04
 Identities = 18/35 (51%), Positives = 24/35 (68%)

Query: 28  DPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRCK 62
           DPF YD  TLR RGL+ A VLF  GI+++   +C+
Sbjct: 133 DPFFYDEHTLRKRGLLVAAVLFITGIIILTSGKCR 167


>gi|21618361 FXYD domain-containing ion transport regulator 5 [Homo
           sapiens]
          Length = 178

 Score = 41.2 bits (95), Expect = 2e-04
 Identities = 18/35 (51%), Positives = 24/35 (68%)

Query: 28  DPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRCK 62
           DPF YD  TLR RGL+ A VLF  GI+++   +C+
Sbjct: 133 DPFFYDEHTLRKRGLLVAAVLFITGIIILTSGKCR 167


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/44 (29%), Positives = 22/44 (50%)

Query: 21 VEREKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRCKCS 64
          ++R++++ P H   Q L    + C+  +     L  LGCR  CS
Sbjct: 16 LQRKERLKPAHIHLQQLTCFSITCSSTMSYSCCLPSLGCRTSCS 59


>gi|188595665 FXYD domain-containing ion transport regulator 2
           isoform 3 [Homo sapiens]
          Length = 145

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 11/25 (44%), Positives = 19/25 (76%)

Query: 33  DYQTLRIRGLVCAVVLFSIGILLIL 57
           DY+T+R  GL+ A + F +G+L++L
Sbjct: 88  DYETVRNGGLIFAGLAFIVGLLILL 112


>gi|46358066 hypothetical protein LOC388325 [Homo sapiens]
          Length = 145

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 9/58 (15%)

Query: 42 LVCAVVLFSIGILLILGCRCKCSFNQ-------KP--RTPGEEEAQVENLITANATKL 90
          L  A+++ S+G+ LIL C CK    +       KP      +EE   EN++  +  +L
Sbjct: 23 LAVAIIVVSVGLGLILYCVCKWQLRRGKKWEIAKPLKHKQVDEEKMYENVLNESPVQL 80


>gi|14270496 protocadherin gamma subfamily B, 3 isoform 2 precursor
           [Homo sapiens]
          Length = 814

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 11/72 (15%)

Query: 10  SLLAHIVLADAVE--------REKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRC 61
           +++ H++ AD+++        R    DP   + Q   +  L    VLF + ++L +  R 
Sbjct: 657 TVMLHLIFADSLQEIQPDLSDRPTPSDP-QAELQFHLVVALALISVLFLLAVILAISLRL 715

Query: 62  KCSFNQKPRTPG 73
           +CS   +P T G
Sbjct: 716 RCS--SRPATEG 725


>gi|11128033 protocadherin gamma subfamily B, 3 isoform 1 precursor
           [Homo sapiens]
          Length = 929

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 11/72 (15%)

Query: 10  SLLAHIVLADAVE--------REKQIDPFHYDYQTLRIRGLVCAVVLFSIGILLILGCRC 61
           +++ H++ AD+++        R    DP   + Q   +  L    VLF + ++L +  R 
Sbjct: 657 TVMLHLIFADSLQEIQPDLSDRPTPSDP-QAELQFHLVVALALISVLFLLAVILAISLRL 715

Query: 62  KCSFNQKPRTPG 73
           +CS   +P T G
Sbjct: 716 RCS--SRPATEG 725


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,437,058
Number of Sequences: 37866
Number of extensions: 117462
Number of successful extensions: 379
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 354
Number of HSP's gapped (non-prelim): 23
length of query: 95
length of database: 18,247,518
effective HSP length: 66
effective length of query: 29
effective length of database: 15,748,362
effective search space: 456702498
effective search space used: 456702498
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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