Search of human proteins with 169172694

Search of human proteins with 169172694

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2
[Homo sapiens]
         (140 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2 ...   290   2e-79
gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2 ...   252   8e-68
gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo sap...   252   8e-68
gi|224282178 GDNF family receptor alpha 1 isoform b preproprotei...   101   2e-22
gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein...   101   2e-22
gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein ...   101   2e-22
gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo sap...    56   8e-09
gi|194394139 notum pectinacetylesterase homolog [Homo sapiens]         28   1.9  
gi|72534670 phospholipase A2-activating protein [Homo sapiens]         28   2.5  
gi|14042925 ring finger protein 26 [Homo sapiens]                      28   3.2  
gi|83816964 Holliday junction recognition protein [Homo sapiens]       26   9.3  
gi|71725367 primary ciliary dyskinesia protein 1 [Homo sapiens]        26   9.3  
gi|4505227 myeloid cell nuclear differentiation antigen [Homo sa...    26   9.3  

>gi|169172694 PREDICTED: similar to GDNF family receptor alpha 2
           [Homo sapiens]
          Length = 140

 Score =  290 bits (743), Expect = 2e-79
 Identities = 140/140 (100%), Positives = 140/140 (100%)

Query: 1   MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60
           MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL
Sbjct: 1   MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60

Query: 61  RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEAE 120
           RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEAE
Sbjct: 61  RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEAE 120

Query: 121 FSLKGEVSEVTELQLKPNFR 140
           FSLKGEVSEVTELQLKPNFR
Sbjct: 121 FSLKGEVSEVTELQLKPNFR 140


>gi|169173216 PREDICTED: similar to GDNF family receptor alpha 2
           [Homo sapiens]
          Length = 364

 Score =  252 bits (643), Expect = 8e-68
 Identities = 123/140 (87%), Positives = 125/140 (89%)

Query: 1   MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60
           MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL
Sbjct: 1   MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60

Query: 61  RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEAE 120
           RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTE E
Sbjct: 61  RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120

Query: 121 FSLKGEVSEVTELQLKPNFR 140
              +    E    +L   FR
Sbjct: 121 EFYEASPYEPVTSRLSDIFR 140


>gi|47078235 GDNF family receptor alpha 2 preproprotein [Homo
           sapiens]
          Length = 464

 Score =  252 bits (643), Expect = 8e-68
 Identities = 123/140 (87%), Positives = 125/140 (89%)

Query: 1   MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60
           MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL
Sbjct: 1   MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTL 60

Query: 61  RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEAE 120
           RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTE E
Sbjct: 61  RQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGE 120

Query: 121 FSLKGEVSEVTELQLKPNFR 140
              +    E    +L   FR
Sbjct: 121 EFYEASPYEPVTSRLSDIFR 140


>gi|224282178 GDNF family receptor alpha 1 isoform b preproprotein
           [Homo sapiens]
          Length = 460

 Score =  101 bits (252), Expect = 2e-22
 Identities = 44/84 (52%), Positives = 64/84 (76%), Gaps = 5/84 (5%)

Query: 38  VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92
           +DCV+A++ C  E +CS++YRTLRQC+AG++ N  LA+      EC++A+E L++  LY+
Sbjct: 27  LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86

Query: 93  CRCKRGMKKELQCLQIYWSIHLGL 116
           CRCKRGMKKE  CL+IYWS++  L
Sbjct: 87  CRCKRGMKKEKNCLRIYWSMYQSL 110


>gi|22035692 GDNF family receptor alpha 1 isoform b preproprotein
           [Homo sapiens]
          Length = 460

 Score =  101 bits (252), Expect = 2e-22
 Identities = 44/84 (52%), Positives = 64/84 (76%), Gaps = 5/84 (5%)

Query: 38  VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92
           +DCV+A++ C  E +CS++YRTLRQC+AG++ N  LA+      EC++A+E L++  LY+
Sbjct: 27  LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86

Query: 93  CRCKRGMKKELQCLQIYWSIHLGL 116
           CRCKRGMKKE  CL+IYWS++  L
Sbjct: 87  CRCKRGMKKEKNCLRIYWSMYQSL 110


>gi|4885269 GDNF family receptor alpha 1 isoform a preproprotein
           [Homo sapiens]
          Length = 465

 Score =  101 bits (252), Expect = 2e-22
 Identities = 44/84 (52%), Positives = 64/84 (76%), Gaps = 5/84 (5%)

Query: 38  VDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLAN-----KECQAALEVLQESPLYD 92
           +DCV+A++ C  E +CS++YRTLRQC+AG++ N  LA+      EC++A+E L++  LY+
Sbjct: 27  LDCVKASDQCLKEQSCSTKYRTLRQCVAGKETNFSLASGLEAKDECRSAMEALKQKSLYN 86

Query: 93  CRCKRGMKKELQCLQIYWSIHLGL 116
           CRCKRGMKKE  CL+IYWS++  L
Sbjct: 87  CRCKRGMKKEKNCLRIYWSMYQSL 110


>gi|22035694 GDNF family receptor alpha 3 preproprotein [Homo
           sapiens]
          Length = 400

 Score = 56.2 bits (134), Expect = 8e-09
 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 8/90 (8%)

Query: 40  CVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKE------CQAALEVLQESPLYDC 93
           C++A   C A+  CS+ Y  L  C +    +T L ++E      C  A + L+ S L  C
Sbjct: 44  CLQARRKCQADPTCSAAYHHLDSCTSSI--STPLPSEEPSVPADCLEAAQQLRNSSLIGC 101

Query: 94  RCKRGMKKELQCLQIYWSIHLGLTEAEFSL 123
            C R MK ++ CL IYW++H   +   + L
Sbjct: 102 MCHRRMKNQVACLDIYWTVHRARSLGNYEL 131


>gi|194394139 notum pectinacetylesterase homolog [Homo sapiens]
          Length = 496

 Score = 28.5 bits (62), Expect = 1.9
 Identities = 15/47 (31%), Positives = 22/47 (46%)

Query: 22  SPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGRD 68
           SP+     E  G R  +  +     C    NC SRY T+R+ ++ RD
Sbjct: 105 SPAGYYLKESRGSRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRD 151


>gi|72534670 phospholipase A2-activating protein [Homo sapiens]
          Length = 795

 Score = 28.1 bits (61), Expect = 2.5
 Identities = 13/56 (23%), Positives = 28/56 (50%), Gaps = 3/56 (5%)

Query: 58  RTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKK---ELQCLQIYW 110
           +T++   AGR   T   +++C   L +L E+    C     +++     +CL++Y+
Sbjct: 173 KTVKLWKAGRCERTFSGHEDCVRGLAILSETEFLSCANDASIRRWQITGECLEVYY 228


>gi|14042925 ring finger protein 26 [Homo sapiens]
          Length = 433

 Score = 27.7 bits (60), Expect = 3.2
 Identities = 12/32 (37%), Positives = 16/32 (50%)

Query: 78  CQAALEVLQESPLYDCRCKRGMKKELQCLQIY 109
           CQA  E+L   P+Y   C    +  LQ L +Y
Sbjct: 401 CQACTEILMRHPVYHRNCPLCRRGILQTLNVY 432


>gi|83816964 Holliday junction recognition protein [Homo sapiens]
          Length = 748

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 17/53 (32%), Positives = 21/53 (39%)

Query: 21  ASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTML 73
           ASP  LQG E      P    +A  L  A  N   R     +CL   D ++ L
Sbjct: 472 ASPGGLQGLETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSDSSSSL 524


>gi|71725367 primary ciliary dyskinesia protein 1 [Homo sapiens]
          Length = 554

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 11/40 (27%), Positives = 24/40 (60%), Gaps = 1/40 (2%)

Query: 90  LYDCRCKRGMKKELQCLQIYWSIHLGLTEAEFSLKGEVSE 129
           L++ + ++ + +E++   + W +HLG     F LK E++E
Sbjct: 73  LFEQKVRQDIHEEMEN-HLKWQVHLGKDPMSFKLKKELTE 111


>gi|4505227 myeloid cell nuclear differentiation antigen [Homo
           sapiens]
          Length = 407

 Score = 26.2 bits (56), Expect = 9.3
 Identities = 10/40 (25%), Positives = 24/40 (60%)

Query: 69  RNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQI 108
           +NT+   ++   +++V+     ++ +C++G K  L CLQ+
Sbjct: 335 KNTIYEIQDNTGSMDVVGSGKWHNIKCEKGDKLRLFCLQL 374


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.135    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,452,133
Number of Sequences: 37866
Number of extensions: 218980
Number of successful extensions: 481
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 466
Number of HSP's gapped (non-prelim): 13
length of query: 140
length of database: 18,247,518
effective HSP length: 92
effective length of query: 48
effective length of database: 14,763,846
effective search space: 708664608
effective search space used: 708664608
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.