Guide to the Human Genome
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Search of human proteins with 169170512

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169170512 PREDICTED: similar to Postmeiotic segregation
increased 4-like protein [Homo sapiens]
         (255 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239743246 PREDICTED: hypothetical protein XP_002342778 [Homo ...   516   e-147
gi|169170512 PREDICTED: similar to Postmeiotic segregation incre...   516   e-147
gi|4505913 PMS2 postmeiotic segregation increased 2 isoform a [H...   316   1e-86
gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]       125   5e-29
gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]       125   5e-29
gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]         125   5e-29
gi|4557757 MutL protein homolog 1 [Homo sapiens]                       98   8e-21
gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]                    58   7e-09
gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]                    58   7e-09
gi|119120861 formin-like 3 isoform 2 [Homo sapiens]                    32   0.54 
gi|119120874 formin-like 3 isoform 1 [Homo sapiens]                    32   0.54 
gi|169211534 PREDICTED: hypothetical protein [Homo sapiens]            32   0.70 
gi|169218016 PREDICTED: hypothetical protein [Homo sapiens]            32   0.70 
gi|169210726 PREDICTED: hypothetical protein [Homo sapiens]            32   0.70 
gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Ho...    28   5.9  
gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Ho...    28   5.9  
gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Ho...    28   5.9  

>gi|239743246 PREDICTED: hypothetical protein XP_002342778 [Homo
           sapiens]
          Length = 255

 Score =  516 bits (1328), Expect = e-147
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MLSVFKKEDTIIAKDFGNLRDTITEPAKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGN 60
           MLSVFKKEDTIIAKDFGNLRDTITEPAKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGN
Sbjct: 1   MLSVFKKEDTIIAKDFGNLRDTITEPAKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGN 60

Query: 61  SLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKHHTSKIREFADLTRVETFG 120
           SLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKHHTSKIREFADLTRVETFG
Sbjct: 61  SLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKHHTSKIREFADLTRVETFG 120

Query: 121 FQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFST 180
           FQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFST
Sbjct: 121 FQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFST 180

Query: 181 LPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQPAKLTPRSTPPHPCSLEDNV 240
           LPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQPAKLTPRSTPPHPCSLEDNV
Sbjct: 181 LPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQPAKLTPRSTPPHPCSLEDNV 240

Query: 241 ITVFSSVKNGPGSSR 255
           ITVFSSVKNGPGSSR
Sbjct: 241 ITVFSSVKNGPGSSR 255


>gi|169170512 PREDICTED: similar to Postmeiotic segregation
           increased 4-like protein [Homo sapiens]
          Length = 255

 Score =  516 bits (1328), Expect = e-147
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MLSVFKKEDTIIAKDFGNLRDTITEPAKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGN 60
           MLSVFKKEDTIIAKDFGNLRDTITEPAKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGN
Sbjct: 1   MLSVFKKEDTIIAKDFGNLRDTITEPAKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGN 60

Query: 61  SLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKHHTSKIREFADLTRVETFG 120
           SLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKHHTSKIREFADLTRVETFG
Sbjct: 61  SLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKHHTSKIREFADLTRVETFG 120

Query: 121 FQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFST 180
           FQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFST
Sbjct: 121 FQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFST 180

Query: 181 LPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQPAKLTPRSTPPHPCSLEDNV 240
           LPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQPAKLTPRSTPPHPCSLEDNV
Sbjct: 181 LPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQPAKLTPRSTPPHPCSLEDNV 240

Query: 241 ITVFSSVKNGPGSSR 255
           ITVFSSVKNGPGSSR
Sbjct: 241 ITVFSSVKNGPGSSR 255


>gi|4505913 PMS2 postmeiotic segregation increased 2 isoform a [Homo
           sapiens]
          Length = 862

 Score =  316 bits (810), Expect = 1e-86
 Identities = 157/174 (90%), Positives = 168/174 (96%)

Query: 24  TEPAKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEV 83
           TEPAKAIKPIDRKSVHQICSG VVLSLSTAVK++V NSLDAGATNIDLKLKDYG+DLIEV
Sbjct: 9   TEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKDYGVDLIEV 68

Query: 84  SGNGCGVEEENFEGLTLKHHTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVS 143
           S NGCGVEEENFEGLTLKHHTSKI+EFADLT+VETFGF+G+ALSSLCALSDVTISTCH S
Sbjct: 69  SDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDVTISTCHAS 128

Query: 144 AKVGTRLVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKKKRA 197
           AKVGTRL+FDH+GKIIQKTPYP PRGTTVSV+QLFSTLPVRHKEFQRNIKK+ A
Sbjct: 129 AKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKKEYA 182


>gi|189458898 postmeiotic segregation 1 isoform c [Homo sapiens]
          Length = 770

 Score =  125 bits (313), Expect = 5e-29
 Identities = 64/165 (38%), Positives = 104/165 (63%), Gaps = 1/165 (0%)

Query: 30  IKPIDRKSVHQICSGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGNGCG 89
           +K +   +V  + S  ++ S+ + VK+++ NSLDAGAT++D+KL++YG D IEV  NG G
Sbjct: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60

Query: 90  VEEENFEGLTLKHHTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKVGTR 149
           ++  +   + +K++TSKI    DL  + T+GF+G+AL S+C +++V I+T   +    T+
Sbjct: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120

Query: 150 LVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKK 194
            V D  G I+ + P    +GTTV+  +LF  LPVR K+F    KK
Sbjct: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVR-KQFYSTAKK 164


>gi|189458896 postmeiotic segregation 1 isoform b [Homo sapiens]
          Length = 893

 Score =  125 bits (313), Expect = 5e-29
 Identities = 64/165 (38%), Positives = 104/165 (63%), Gaps = 1/165 (0%)

Query: 30  IKPIDRKSVHQICSGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGNGCG 89
           +K +   +V  + S  ++ S+ + VK+++ NSLDAGAT++D+KL++YG D IEV  NG G
Sbjct: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60

Query: 90  VEEENFEGLTLKHHTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKVGTR 149
           ++  +   + +K++TSKI    DL  + T+GF+G+AL S+C +++V I+T   +    T+
Sbjct: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120

Query: 150 LVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKK 194
            V D  G I+ + P    +GTTV+  +LF  LPVR K+F    KK
Sbjct: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVR-KQFYSTAKK 164


>gi|4505911 postmeiotic segregation 1 isoform a [Homo sapiens]
          Length = 932

 Score =  125 bits (313), Expect = 5e-29
 Identities = 64/165 (38%), Positives = 104/165 (63%), Gaps = 1/165 (0%)

Query: 30  IKPIDRKSVHQICSGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGNGCG 89
           +K +   +V  + S  ++ S+ + VK+++ NSLDAGAT++D+KL++YG D IEV  NG G
Sbjct: 1   MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG 60

Query: 90  VEEENFEGLTLKHHTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKVGTR 149
           ++  +   + +K++TSKI    DL  + T+GF+G+AL S+C +++V I+T   +    T+
Sbjct: 61  IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ 120

Query: 150 LVFDHDGKIIQKTPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKK 194
            V D  G I+ + P    +GTTV+  +LF  LPVR K+F    KK
Sbjct: 121 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVR-KQFYSTAKK 164


>gi|4557757 MutL protein homolog 1 [Homo sapiens]
          Length = 756

 Score = 97.8 bits (242), Expect = 8e-21
 Identities = 56/164 (34%), Positives = 99/164 (60%), Gaps = 8/164 (4%)

Query: 27  AKAIKPIDRKSVHQICSGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGN 86
           A  I+ +D   V++I +G V+   + A+K+++ N LDA +T+I + +K+ G+ LI++  N
Sbjct: 5   AGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDN 64

Query: 87  GCGVEEENFEGLTLKHHTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKV 146
           G G+ +E+ + +  +  TSK++ F DL  + T+GF+G+AL+S+  ++ VTI+T     K 
Sbjct: 65  GTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKC 124

Query: 147 GTRLVFDHDGKIIQKTPYPHP----RGTTVSVKQLFSTLPVRHK 186
             R  +  DGK+  K P P P    +GT ++V+ LF  +  R K
Sbjct: 125 AYRASYS-DGKL--KAP-PKPCAGNQGTQITVEDLFYNIATRRK 164


>gi|91992162 mutL homolog 3 isoform 1 [Homo sapiens]
          Length = 1453

 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 41/147 (27%), Positives = 73/147 (49%), Gaps = 4/147 (2%)

Query: 43  SGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKH 102
           SG  + SL   V+++  NS+DA A  + +++       ++V  NG G+  ++ E +  ++
Sbjct: 15  SGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQ-VQVIDNGFGMGSDDVEKVGNRY 73

Query: 103 HTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKT 162
            TSK     DL     +GF+G+AL+++  ++     +   +  + T +     GK ++  
Sbjct: 74  FTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALKAC 133

Query: 163 PYPHPR---GTTVSVKQLFSTLPVRHK 186
                R   GTTV+V  LF  LPVR K
Sbjct: 134 EADVTRASAGTTVTVYNLFYQLPVRRK 160


>gi|91992160 mutL homolog 3 isoform 2 [Homo sapiens]
          Length = 1429

 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 41/147 (27%), Positives = 73/147 (49%), Gaps = 4/147 (2%)

Query: 43  SGPVVLSLSTAVKKIVGNSLDAGATNIDLKLKDYGMDLIEVSGNGCGVEEENFEGLTLKH 102
           SG  + SL   V+++  NS+DA A  + +++       ++V  NG G+  ++ E +  ++
Sbjct: 15  SGLAISSLGQCVEELALNSIDAEAKCVAVRVNMETFQ-VQVIDNGFGMGSDDVEKVGNRY 73

Query: 103 HTSKIREFADLTRVETFGFQGKALSSLCALSDVTISTCHVSAKVGTRLVFDHDGKIIQKT 162
            TSK     DL     +GF+G+AL+++  ++     +   +  + T +     GK ++  
Sbjct: 74  FTSKCHSVQDLENPRFYGFRGEALANIADMASAVEISSKKNRTMKTFVKLFQSGKALKAC 133

Query: 163 PYPHPR---GTTVSVKQLFSTLPVRHK 186
                R   GTTV+V  LF  LPVR K
Sbjct: 134 EADVTRASAGTTVTVYNLFYQLPVRRK 160


>gi|119120861 formin-like 3 isoform 2 [Homo sapiens]
          Length = 976

 Score = 32.0 bits (71), Expect = 0.54
 Identities = 18/46 (39%), Positives = 21/46 (45%), Gaps = 1/46 (2%)

Query: 211 EGSPAMLPVQPAKLTPRSTP-PHPCSLEDNVITVFSSVKNGPGSSR 255
           EG P   P  P  L P   P P PC LE+    V SS+   P  +R
Sbjct: 8   EGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKAR 53


>gi|119120874 formin-like 3 isoform 1 [Homo sapiens]
          Length = 1027

 Score = 32.0 bits (71), Expect = 0.54
 Identities = 18/46 (39%), Positives = 21/46 (45%), Gaps = 1/46 (2%)

Query: 211 EGSPAMLPVQPAKLTPRSTP-PHPCSLEDNVITVFSSVKNGPGSSR 255
           EG P   P  P  L P   P P PC LE+    V SS+   P  +R
Sbjct: 8   EGVPGEPPSVPLLLPPGKMPMPEPCELEERFALVLSSMNLPPDKAR 53


>gi|169211534 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 205

 Score = 31.6 bits (70), Expect = 0.70
 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 6/85 (7%)

Query: 162 TPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQP 221
           TP PH  G  V+  +  S  P    E  + +    A F  ++ R C  L G  AM+P Q 
Sbjct: 66  TPVPHSAGPQVT--RFHSPSPPHISELSQTL---HAPFQGSWPRPCHALSGPRAMVPNQL 120

Query: 222 AKLTP-RSTPPHPCSLEDNVITVFS 245
              TP  +  PH C++      +F+
Sbjct: 121 HPGTPCPAHVPHSCTMPAGTCPLFT 145


>gi|169218016 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 205

 Score = 31.6 bits (70), Expect = 0.70
 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 6/85 (7%)

Query: 162 TPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQP 221
           TP PH  G  V+  +  S  P    E  + +    A F  ++ R C  L G  AM+P Q 
Sbjct: 66  TPVPHSAGPQVT--RFHSPSPPHISELSQTL---HAPFQGSWPRPCHALSGPRAMVPNQL 120

Query: 222 AKLTP-RSTPPHPCSLEDNVITVFS 245
              TP  +  PH C++      +F+
Sbjct: 121 HPGTPCPAHVPHSCTMPAGTCPLFT 145


>gi|169210726 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 205

 Score = 31.6 bits (70), Expect = 0.70
 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 6/85 (7%)

Query: 162 TPYPHPRGTTVSVKQLFSTLPVRHKEFQRNIKKKRACFPFAFCRDCQFLEGSPAMLPVQP 221
           TP PH  G  V+  +  S  P    E  + +    A F  ++ R C  L G  AM+P Q 
Sbjct: 66  TPVPHSAGPQVT--RFHSPSPPHISELSQTL---HAPFQGSWPRPCHALSGPRAMVPNQL 120

Query: 222 AKLTP-RSTPPHPCSLEDNVITVFS 245
              TP  +  PH C++      +F+
Sbjct: 121 HPGTPCPAHVPHSCTMPAGTCPLFT 145


>gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Homo
           sapiens]
          Length = 1542

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 1/31 (3%)

Query: 206 DCQFLEGS-PAMLPVQPAKLTPRSTPPHPCS 235
           DC    G+ PA LP  P    P + PPH C+
Sbjct: 386 DCTLYPGNLPADLPTPPETSVPVTLPPHNCT 416


>gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Homo
           sapiens]
          Length = 1817

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 1/31 (3%)

Query: 206 DCQFLEGS-PAMLPVQPAKLTPRSTPPHPCS 235
           DC    G+ PA LP  P    P + PPH C+
Sbjct: 661 DCTLYPGNLPADLPTPPETSVPVTLPPHNCT 691


>gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Homo
           sapiens]
          Length = 1817

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 1/31 (3%)

Query: 206 DCQFLEGS-PAMLPVQPAKLTPRSTPPHPCS 235
           DC    G+ PA LP  P    P + PPH C+
Sbjct: 661 DCTLYPGNLPADLPTPPETSVPVTLPPHNCT 691


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,399,772
Number of Sequences: 37866
Number of extensions: 465601
Number of successful extensions: 1207
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1196
Number of HSP's gapped (non-prelim): 17
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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