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Search of human proteins with 168693643
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
(440 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|168693643 decay accelerating factor for complement isoform 2 ... 924 0.0
gi|10835143 decay accelerating factor for complement isoform 1 p... 761 0.0
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 168 8e-42
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 168 8e-42
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 155 7e-38
gi|4502503 complement component 4 binding protein, alpha chain p... 154 1e-37
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 119 7e-27
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 119 7e-27
gi|148886654 polydom [Homo sapiens] 116 4e-26
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 108 1e-23
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 108 1e-23
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 108 1e-23
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 107 2e-23
gi|27502421 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502419 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502417 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502415 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502413 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502411 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502409 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502407 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502405 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502402 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|24432108 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502427 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502425 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|27502423 CD46 antigen, complement regulatory protein isoform ... 107 3e-23
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 97 3e-20
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 97 3e-20
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 97 3e-20
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 924 bits (2389), Expect = 0.0
Identities = 440/440 (100%), Positives = 440/440 (100%)
Query: 1 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV 60
MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
Sbjct: 1 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV 60
Query: 61 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP 120
ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
Sbjct: 61 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP 120
Query: 121 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI 180
VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
Sbjct: 121 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI 180
Query: 181 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER 240
LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
Sbjct: 181 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER 240
Query: 241 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT 300
DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
Sbjct: 241 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT 300
Query: 301 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS 360
TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
Sbjct: 301 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS 360
Query: 361 GSRPVTQAGMRWCDRSSLQSRTPGFKRSFHFSLPSSWYYRAHVFHVDRFAWDASNHGLAD 420
GSRPVTQAGMRWCDRSSLQSRTPGFKRSFHFSLPSSWYYRAHVFHVDRFAWDASNHGLAD
Sbjct: 361 GSRPVTQAGMRWCDRSSLQSRTPGFKRSFHFSLPSSWYYRAHVFHVDRFAWDASNHGLAD 420
Query: 421 LAKEELRRKYTQVYRLFLVS 440
LAKEELRRKYTQVYRLFLVS
Sbjct: 421 LAKEELRRKYTQVYRLFLVS 440
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 761 bits (1965), Expect = 0.0
Identities = 363/370 (98%), Positives = 364/370 (98%)
Query: 1 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV 60
MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV
Sbjct: 1 MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTV 60
Query: 61 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP 120
ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP
Sbjct: 61 ITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFP 120
Query: 121 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI 180
VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI
Sbjct: 121 VGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGI 180
Query: 181 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER 240
LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER
Sbjct: 181 LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER 240
Query: 241 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT 300
DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT
Sbjct: 241 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT 300
Query: 301 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS 360
TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS
Sbjct: 301 TVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLS 360
Query: 361 GSRPVTQAGM 370
G T G+
Sbjct: 361 GHTCFTLTGL 370
>gi|86793109 complement receptor 1 isoform S precursor [Homo
sapiens]
Length = 2489
Score = 168 bits (426), Expect = 8e-42
Identities = 101/268 (37%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEE------SFVKIPGEKDSVICLKGSQ--- 86
C PP +PN + + FP + Y C+ SF I GE ++ C Q
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI-GES-TIRCTSDPQGNG 478
Query: 87 -WSDIEEFCN--RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKL 143
WS C C+ P A LK + FP+GT ++YECRP Y P +
Sbjct: 479 VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYYGRPF---SI 534
Query: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
TCL NL WS+ + CK+KSC P + NG + V I G+ I++SC TG++L G +S+
Sbjct: 535 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
Query: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG------ 256
C++SG++ WS P C+ I C PP I NG I R+++ Y VTY CN G
Sbjct: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKV 654
Query: 257 FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 655 FELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 168 bits (426), Expect = 8e-42
Identities = 101/268 (37%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEE------SFVKIPGEKDSVICLKGSQ--- 86
C PP +PN + + FP + Y C+ SF I GE ++ C Q
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI-GES-TIRCTSDPQGNG 928
Query: 87 -WSDIEEFCN--RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKL 143
WS C C+ P A LK + FP+GT ++YECRP Y P +
Sbjct: 929 VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYYGRPF---SI 984
Query: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
TCL NL WS+ + CK+KSC P + NG + V I G+ I++SC TG++L G +S+
Sbjct: 985 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 1044
Query: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG------ 256
C++SG++ WS P C+ I C PP I NG I R+++ Y VTY CN G
Sbjct: 1045 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKV 1104
Query: 257 FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 1105 FELVGEPSIYCTSNDDQVGIWSGPAPQC 1132
Score = 168 bits (425), Expect = 1e-41
Identities = 101/268 (37%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEE------SFVKIPGEKDSVICLKGSQ--- 86
C PP +PN + + FP + Y C+ SF I GE ++ C Q
Sbjct: 1321 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLI-GES-TIRCTSDPQGNG 1378
Query: 87 -WSDIEEFCN--RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKL 143
WS C C+ P A LK + FP+GT ++YECRP Y P +
Sbjct: 1379 VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYYGRPF---SI 1434
Query: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
TCL NL WS+ + CK+KSC P + NG + V I G+ I++SC TG++L G +S+
Sbjct: 1435 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 1494
Query: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG------ 256
C++SG++ WS P C+ I C PP I NG I R+++ Y VTY CN G
Sbjct: 1495 CILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKV 1554
Query: 257 FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 1555 FELVGEPSIYCTSNDDQVGIWSGPAPQC 1582
Score = 162 bits (410), Expect = 6e-40
Identities = 80/173 (46%), Positives = 106/173 (61%), Gaps = 11/173 (6%)
Query: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPG 178
FP+GT + YECRPGY P + CL+N W+ A + C++KSC NP + NG + V
Sbjct: 63 FPIGTYLNYECRPGYSGRPF---SIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIK 119
Query: 179 GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQ 237
GI FG+ I +SC GY+L GS+S+ C+ISG +V W + P C I C PP I NG I
Sbjct: 120 GIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
Query: 238 GERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
R+++ Y VTY CN G F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232
Score = 155 bits (391), Expect = 9e-38
Identities = 95/270 (35%), Positives = 131/270 (48%), Gaps = 27/270 (10%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEES-----FVKIPGEKDSVICLKGSQ---- 86
C PP + N + P I+Y C+ + GE ++ C
Sbjct: 1771 CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGES-TIRCTSDPHGNGV 1829
Query: 87 WSDIEEFCNRS-----CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSP 141
WS C S C+ P + AS P I FPVGT + YECRPGY +
Sbjct: 1830 WSSPAPRCELSVRAGHCKTPEQFPFASPTIP-INDFEFPVGTSLNYECRPGYFGKMF--- 1885
Query: 142 KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTS 201
++CL+NL WS+ + C++KSC P E NG + + FG+T+++SCN G++L GS S
Sbjct: 1886 SISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPS 1945
Query: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG---- 256
+ CL+SG++V W P C I C PP I NG R + VTY C+ G
Sbjct: 1946 TTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGE 2005
Query: 257 --FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
F ++GE SIYCT +D+ G WS PPP C
Sbjct: 2006 QLFELVGERSIYCTSKDDQVGVWSSPPPRC 2035
Score = 136 bits (342), Expect = 4e-32
Identities = 80/254 (31%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 297
Query: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
+ P + A Q ++ F G V Y C PGY + S + C WS A C
Sbjct: 298 QPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGAAS--MRCTPQGDWSPAAPTC 353
Query: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
+ KSC + G++ NG++ P + GA + F C+ G++L GS++S+C+++G W+ +
Sbjct: 354 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 413
Query: 218 PECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
P C +I+CP+PP I NG G+ + + + ++V Y C+ F +IGE +I CT +
Sbjct: 414 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSD 473
Query: 271 -NDEGEWSGPPPEC 283
G WS P P C
Sbjct: 474 PQGNGVWSSPAPRC 487
Score = 136 bits (342), Expect = 4e-32
Identities = 80/254 (31%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 690 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 747
Query: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
+ P + A Q ++ F G V Y C PGY + S + C WS A C
Sbjct: 748 QPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGAAS--MRCTPQGDWSPAAPTC 803
Query: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
+ KSC + G++ NG++ P + GA + F C+ G++L GS++S+C+++G W+ +
Sbjct: 804 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 863
Query: 218 PECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
P C +I+CP+PP I NG G+ + + + ++V Y C+ F +IGE +I CT +
Sbjct: 864 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSD 923
Query: 271 -NDEGEWSGPPPEC 283
G WS P P C
Sbjct: 924 PQGNGVWSSPAPRC 937
Score = 136 bits (342), Expect = 4e-32
Identities = 80/254 (31%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 1197
Query: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
+ P + A Q ++ F G V Y C PGY + S + C WS A C
Sbjct: 1198 QPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGAAS--MRCTPQGDWSPAAPTC 1253
Query: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
+ KSC + G++ NG++ P + GA + F C+ G++L GS++S+C+++G W+ +
Sbjct: 1254 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 1313
Query: 218 PECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
P C +I+CP+PP I NG G+ + + + ++V Y C+ F +IGE +I CT +
Sbjct: 1314 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSD 1373
Query: 271 -NDEGEWSGPPPEC 283
G WS P P C
Sbjct: 1374 PQGNGVWSSPAPRC 1387
Score = 127 bits (320), Expect = 2e-29
Identities = 78/253 (30%), Positives = 120/253 (47%), Gaps = 15/253 (5%)
Query: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCE 99
P+V NA R+ F +I ++C+ FV + +V C +W C+R C+
Sbjct: 2044 PEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSH--TVQCQTNGRWGPKLPHCSRVCQ 2101
Query: 100 VPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCK 159
P + + Q+ F G V Y C P Y + S L C WS C
Sbjct: 2102 PPPEILHGEHTLSH--QDNFSPGQEVFYSCEPSYDLRGAAS--LHCTPQGDWSPEAPRCT 2157
Query: 160 KKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLP 218
KSC + G++ +G++ +P + GA +SF C+ G++L G ++S C+++G W+ +P
Sbjct: 2158 VKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVP 2217
Query: 219 ECREIYCPAPPQIDNGIIQGER-DHYGYRQSVTYACN------KGFTMIGEHSIYCTVN- 270
C +I+CP PP I NG G Y + ++YAC+ F +IGE SI CT +
Sbjct: 2218 VCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDP 2277
Query: 271 NDEGEWSGPPPEC 283
G WS P P C
Sbjct: 2278 QGNGVWSSPAPRC 2290
Score = 125 bits (313), Expect = 1e-28
Identities = 79/254 (31%), Positives = 123/254 (48%), Gaps = 15/254 (5%)
Query: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 1590 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 1647
Query: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
+ P + + Q+ F G V Y C PGY + S L C WS C
Sbjct: 1648 QPPPEILHGEHTPSH--QDNFSPGQEVFYSCEPGYDLRGAAS--LHCTPQGDWSPEAPRC 1703
Query: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
KSC + G++ +G++ P + GA +SF C+ G++L GS+ S C++ G W++ +
Sbjct: 1704 AVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSV 1763
Query: 218 PECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
P C I+CP PP I NG G Y + ++Y C+ F +IGE +I CT +
Sbjct: 1764 PVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSD 1823
Query: 271 -NDEGEWSGPPPEC 283
+ G WS P P C
Sbjct: 1824 PHGNGVWSSPAPRC 1837
Score = 115 bits (288), Expect = 8e-26
Identities = 84/291 (28%), Positives = 125/291 (42%), Gaps = 30/291 (10%)
Query: 21 LLLLVLLCLPAVWGDCGLPPDVPNAQPA-LEGRTSFPEDTVITYKCEESFVKIPGEKDSV 79
L ++VLL LP WG C P +P A+P L FP T + Y+C + G S+
Sbjct: 28 LAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGY---SGRPFSI 84
Query: 80 ICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPS 138
ICLK S W+ ++ C R SC P + + ++ + G+ ++Y C GYR S
Sbjct: 85 ICLKNSVWTGAKDRCRRKSCRNPPDPVNGMV---HVIKG-IQFGSQIKYSCTKGYRLIGS 140
Query: 139 LSPKLTCL---QNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG 193
S TC+ + W C + C P I NG +G+ +++ CN G
Sbjct: 141 SS--ATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPG 198
Query: 194 ------YKLFGSTSSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGI-IQGERDHYGY 245
++L G S +C + V WS P P+C PP ++NGI + R +
Sbjct: 199 SGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSL 258
Query: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
+ V + C GF M G + C N +W P C S + PP V
Sbjct: 259 NEVVEFRCQPGFVMKGPRRVKCQALN---KWEPELPSC---SRVCQPPPDV 303
Score = 114 bits (284), Expect = 2e-25
Identities = 80/278 (28%), Positives = 115/278 (41%), Gaps = 30/278 (10%)
Query: 34 GDCGLPPDVPNAQPALE-GRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEE 92
G C P P A P + FP T + Y+C + G+ S+ CL+ WS +E+
Sbjct: 1844 GHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVED 1900
Query: 93 FCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCL---QN 148
C R SC P + + TQ G+ V Y C G+R S P TCL N
Sbjct: 1901 NCRRKSCGPPPEPFNGMVHINTDTQ----FGSTVNYSCNEGFRLIGS--PSTTCLVSGNN 1954
Query: 149 LKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF--GATISFSCNTG------YKLFGST 200
+ W C+ SC P I NG F G +++ C+TG ++L G
Sbjct: 1955 VTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER 2014
Query: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGI-IQGERDHYGYRQSVTYACNKGFT 258
S +C V WS P P C P+++N I + G R + + + + C GF
Sbjct: 2015 SIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFV 2074
Query: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
M+G H++ C N G W P C S + PP +
Sbjct: 2075 MVGSHTVQCQTN---GRWGPKLPHC---SRVCQPPPEI 2106
Score = 94.0 bits (232), Expect = 2e-19
Identities = 78/266 (29%), Positives = 122/266 (45%), Gaps = 27/266 (10%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
C PP++ + + L + +F + Y CE S+ + G S+ C WS C
Sbjct: 2100 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY-DLRGAA-SLHCTPQGDWSPEAPRCT 2157
Query: 96 -RSC-EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYR-REPSLSPKLTCLQNLKWS 152
+SC + +L + P Q +G V + C G+R + S S + W+
Sbjct: 2158 VKSCDDFLGQLPHGRVLLPLNLQ----LGAKVSFVCDEGFRLKGRSASHCVLAGMKALWN 2213
Query: 153 TAVEFCKKKSCPNPGEIRNGQ-IDVP-GGILFGATISFSCNT------GYKLFGSTSSFC 204
++V C++ CPNP I NG+ P G I +G IS++C+T + L G +S C
Sbjct: 2214 SSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRC 2273
Query: 205 LI--SGSSVQWSDPLPECR---EIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKGFT 258
G+ V WS P P C CP PP+I NG I G Y +++Y C+ G+
Sbjct: 2274 TSDPQGNGV-WSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 2332
Query: 259 MIGEHSIYCTVNNDEGEWSGPPPECR 284
++G+ I+CT D+G WS C+
Sbjct: 2333 LVGKGFIFCT---DQGIWSQLDHYCK 2355
Score = 90.1 bits (222), Expect = 4e-18
Identities = 75/278 (26%), Positives = 113/278 (40%), Gaps = 26/278 (9%)
Query: 32 VWGDCGLPPDVPNAQPALEGRTS-FPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI 90
+ G C P A+ + S FP T + Y+C + G S+ CL WS
Sbjct: 489 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY---GRPFSITCLDNLVWSSP 545
Query: 91 EEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL 149
++ C R SC+ P + + IT VG+ + Y C G+R S + N
Sbjct: 546 KDVCKRKSCKTPPDPVNGMVH--VITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNA 601
Query: 150 K-WSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG------YKLFGST 200
WST C++ C P I NG +G+ +++ CN G ++L G
Sbjct: 602 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 661
Query: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACNKGFT 258
S +C + V WS P P+C PP ++NGI+ + R + + V + C GF
Sbjct: 662 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 721
Query: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
M G + C N +W P C S + PP V
Sbjct: 722 MKGPRRVKCQALN---KWEPELPSC---SRVCQPPPDV 753
Score = 90.1 bits (222), Expect = 4e-18
Identities = 75/278 (26%), Positives = 113/278 (40%), Gaps = 26/278 (9%)
Query: 32 VWGDCGLPPDVPNAQPALEGRTS-FPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI 90
+ G C P A+ + S FP T + Y+C + G S+ CL WS
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY---GRPFSITCLDNLVWSSP 995
Query: 91 EEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL 149
++ C R SC+ P + + IT VG+ + Y C G+R S + N
Sbjct: 996 KDVCKRKSCKTPPDPVNGMVH--VITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNA 1051
Query: 150 K-WSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG------YKLFGST 200
WST C++ C P I NG +G+ +++ CN G ++L G
Sbjct: 1052 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 1111
Query: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACNKGFT 258
S +C + V WS P P+C PP ++NGI+ + R + + V + C GF
Sbjct: 1112 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 1171
Query: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
M G + C N +W P C S + PP V
Sbjct: 1172 MKGPRRVKCQALN---KWEPELPSC---SRVCQPPPDV 1203
Score = 89.7 bits (221), Expect = 5e-18
Identities = 74/278 (26%), Positives = 113/278 (40%), Gaps = 26/278 (9%)
Query: 32 VWGDCGLPPDVPNAQPALEGRTS-FPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI 90
+ G C P A+ + S FP T + Y+C + G S+ CL WS
Sbjct: 1389 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY---GRPFSITCLDNLVWSSP 1445
Query: 91 EEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL 149
++ C R SC+ P + + IT VG+ + Y C G+R S + N
Sbjct: 1446 KDVCKRKSCKTPPDPVNGMVH--VITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNT 1501
Query: 150 K-WSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG------YKLFGST 200
WST C++ C P I NG +G+ +++ CN G ++L G
Sbjct: 1502 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEP 1561
Query: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACNKGFT 258
S +C + V WS P P+C PP ++NGI+ + R + + V + C GF
Sbjct: 1562 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 1621
Query: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
M G + C N +W P C S + PP +
Sbjct: 1622 MKGPRRVKCQALN---KWEPELPSC---SRVCQPPPEI 1653
Score = 83.6 bits (205), Expect = 3e-16
Identities = 74/267 (27%), Positives = 109/267 (40%), Gaps = 28/267 (10%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ--WSDIEEF 93
CG PP+ N + T F + + Y C E F ++ G + + G+ W
Sbjct: 1907 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGF-RLIGSPSTTCLVSGNNVTWDKKAPI 1963
Query: 94 CNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCL-- 146
C SCE P +++ T F GTVV Y+C G E + C
Sbjct: 1964 CEIISCEPPPTISNGDFYSNNRTS--FHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 2021
Query: 147 --QNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGAT---ISFSCNTGYKLFGSTS 201
Q WS+ C + E+ N I VPG F I F C G+ + GS +
Sbjct: 2022 DDQVGVWSSPPPRCISTNKCTAPEVENA-IRVPGNRSFFTLTEIIRFRCQPGFVMVGSHT 2080
Query: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI-IQGERDHYGYRQSVTYACNKGFTMI 260
C +G +W LP C + C PP+I +G +D++ Q V Y+C + +
Sbjct: 2081 VQCQTNG---RWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 2136
Query: 261 GEHSIYCTVNNDEGEWSGPPPECRGKS 287
G S++CT +G+WS P C KS
Sbjct: 2137 GAASLHCT---PQGDWSPEAPRCTVKS 2160
Score = 67.8 bits (164), Expect = 2e-11
Identities = 78/288 (27%), Positives = 123/288 (42%), Gaps = 41/288 (14%)
Query: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
LP+ C PPDV +A+ + +F + Y CE + + G S+ C WS
Sbjct: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY-DLRGAA-SMRCTPQGDWS 347
Query: 89 DIEEFCN-RSCE--VPTRLNSASLKQPYITQNYFPV----GTVVEYECRPGYRREPSLSP 141
C +SC+ + LN L FPV G V++ C G++ + S +
Sbjct: 348 PAAPTCEVKSCDDFMGQLLNGRVL---------FPVNLQLGAKVDFVCDEGFQLKGSSAS 398
Query: 142 --KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ-IDVPGGIL-FGATISFSCN------ 191
L +++L W+++V C++ CP+P I NG+ P + FG T++++C+
Sbjct: 399 YCVLAGMESL-WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRG 457
Query: 192 TGYKLFGSTSSFCLI--SGSSVQWSDPLPECREI-YCPAPPQIDNGII--QGERDHYGYR 246
T + L G ++ C G+ V WS P P C + +C AP + Q +
Sbjct: 458 TSFDLIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIG 516
Query: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP 294
S+ Y C + SI C D WS P C+ KS K PP
Sbjct: 517 TSLKYECRPEY-YGRPFSITCL---DNLVWSSPKDVCKRKS--CKTPP 558
Score = 67.8 bits (164), Expect = 2e-11
Identities = 78/288 (27%), Positives = 123/288 (42%), Gaps = 41/288 (14%)
Query: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
LP+ C PPDV +A+ + +F + Y CE + + G S+ C WS
Sbjct: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY-DLRGAA-SMRCTPQGDWS 797
Query: 89 DIEEFCN-RSCE--VPTRLNSASLKQPYITQNYFPV----GTVVEYECRPGYRREPSLSP 141
C +SC+ + LN L FPV G V++ C G++ + S +
Sbjct: 798 PAAPTCEVKSCDDFMGQLLNGRVL---------FPVNLQLGAKVDFVCDEGFQLKGSSAS 848
Query: 142 --KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ-IDVPGGIL-FGATISFSCN------ 191
L +++L W+++V C++ CP+P I NG+ P + FG T++++C+
Sbjct: 849 YCVLAGMESL-WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRG 907
Query: 192 TGYKLFGSTSSFCLI--SGSSVQWSDPLPECREI-YCPAPPQIDNGII--QGERDHYGYR 246
T + L G ++ C G+ V WS P P C + +C AP + Q +
Sbjct: 908 TSFDLIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIG 966
Query: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP 294
S+ Y C + SI C D WS P C+ KS K PP
Sbjct: 967 TSLKYECRPEY-YGRPFSITCL---DNLVWSSPKDVCKRKS--CKTPP 1008
Score = 65.9 bits (159), Expect = 7e-11
Identities = 77/288 (26%), Positives = 122/288 (42%), Gaps = 41/288 (14%)
Query: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
LP+ C PPDV +A+ + +F + Y CE + + G S+ C WS
Sbjct: 1190 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY-DLRGAA-SMRCTPQGDWS 1247
Query: 89 DIEEFCN-RSCE--VPTRLNSASLKQPYITQNYFPV----GTVVEYECRPGYRREPSLSP 141
C +SC+ + LN L FPV G V++ C G++ + S +
Sbjct: 1248 PAAPTCEVKSCDDFMGQLLNGRVL---------FPVNLQLGAKVDFVCDEGFQLKGSSAS 1298
Query: 142 --KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ-IDVPGGIL-FGATISFSCN------ 191
L +++L W+++V C++ CP+P I NG+ P + FG ++++C+
Sbjct: 1299 YCVLAGMESL-WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRG 1357
Query: 192 TGYKLFGSTSSFCLI--SGSSVQWSDPLPECREI-YCPAPPQIDNGII--QGERDHYGYR 246
T + L G ++ C G+ V WS P P C + +C AP + Q +
Sbjct: 1358 TSFDLIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIG 1416
Query: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP 294
S+ Y C + SI C D WS P C+ KS K PP
Sbjct: 1417 TSLKYECRPEY-YGRPFSITCL---DNLVWSSPKDVCKRKS--CKTPP 1458
Score = 65.5 bits (158), Expect = 9e-11
Identities = 67/269 (24%), Positives = 101/269 (37%), Gaps = 33/269 (12%)
Query: 49 LEGRTSFPED----TVITYKCEESFVKIPGEKDSVICLKG--SQWSDIEEFCNRS-CEVP 101
L GR FP + + + C+E F ++ G S L G S W+ C + C P
Sbjct: 366 LNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSP 424
Query: 102 TRL-NSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWS 152
+ N +P FP G V Y C P R S + C N WS
Sbjct: 425 PVIPNGRHTGKPL---EVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 481
Query: 153 TAVEFCKKKS-CPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISG 208
+ C C P ++ G ++ + C Y +G S +
Sbjct: 482 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD- 538
Query: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKGFTMIGEHSIYC 267
++ WS P C+ C PP NG++ D G R + Y+C G +IG S C
Sbjct: 539 -NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSR--INYSCTTGHRLIGHSSAEC 595
Query: 268 TVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
++ + WS PP C + + +PPT+
Sbjct: 596 ILSGNAAHWSTKPPIC--QRIPCGLPPTI 622
Score = 65.5 bits (158), Expect = 9e-11
Identities = 67/269 (24%), Positives = 101/269 (37%), Gaps = 33/269 (12%)
Query: 49 LEGRTSFPED----TVITYKCEESFVKIPGEKDSVICLKG--SQWSDIEEFCNRS-CEVP 101
L GR FP + + + C+E F ++ G S L G S W+ C + C P
Sbjct: 816 LNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSP 874
Query: 102 TRL-NSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWS 152
+ N +P FP G V Y C P R S + C N WS
Sbjct: 875 PVIPNGRHTGKPL---EVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
Query: 153 TAVEFCKKKS-CPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISG 208
+ C C P ++ G ++ + C Y +G S +
Sbjct: 932 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD- 988
Query: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKGFTMIGEHSIYC 267
++ WS P C+ C PP NG++ D G R + Y+C G +IG S C
Sbjct: 989 -NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSR--INYSCTTGHRLIGHSSAEC 1045
Query: 268 TVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
++ + WS PP C + + +PPT+
Sbjct: 1046 ILSGNAAHWSTKPPIC--QRIPCGLPPTI 1072
Score = 65.5 bits (158), Expect = 9e-11
Identities = 67/269 (24%), Positives = 101/269 (37%), Gaps = 33/269 (12%)
Query: 49 LEGRTSFPED----TVITYKCEESFVKIPGEKDSVICLKG--SQWSDIEEFCNRS-CEVP 101
L GR FP + + + C+E F ++ G S L G S W+ C + C P
Sbjct: 1266 LNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSP 1324
Query: 102 TRL-NSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWS 152
+ N +P FP G V Y C P R S + C N WS
Sbjct: 1325 PVIPNGRHTGKPL---EVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 1381
Query: 153 TAVEFCKKKS-CPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISG 208
+ C C P ++ G ++ + C Y +G S +
Sbjct: 1382 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD- 1438
Query: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKGFTMIGEHSIYC 267
++ WS P C+ C PP NG++ D G R + Y+C G +IG S C
Sbjct: 1439 -NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSR--INYSCTTGHRLIGHSSAEC 1495
Query: 268 TVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
++ + WS PP C + + +PPT+
Sbjct: 1496 ILSGNTAHWSTKPPIC--QRIPCGLPPTI 1522
Score = 62.4 bits (150), Expect = 8e-10
Identities = 64/247 (25%), Positives = 100/247 (40%), Gaps = 32/247 (12%)
Query: 61 ITYKCEESFVKIPGEKDSVICLKGSQ--WSDIEEFCNRSC--EVPTRLNSASLKQPYITQ 116
+++ C+E F ++ G S L G + W+ C + P LN P+
Sbjct: 2185 VSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPF--- 2240
Query: 117 NYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWSTAVEFCKKK---SCPN 165
P G + Y C R + + + C N WS+ C+ +CP+
Sbjct: 2241 GDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPH 2300
Query: 166 PGEIRNGQIDVPGGI---LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECRE 222
P +I+NG + G + L G TIS+ C+ GY L G FC G WS C+E
Sbjct: 2301 PPKIQNGHY-IGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGI---WSQLDHYCKE 2356
Query: 223 IYCPAPPQIDNGIIQ--GERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
+ C + P NGI + + Y Y VT C G+T+ G C ++ W P
Sbjct: 2357 VNC-SFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADD---RWDPPL 2412
Query: 281 PECRGKS 287
+C ++
Sbjct: 2413 AKCTSRT 2419
Score = 61.6 bits (148), Expect = 1e-09
Identities = 74/279 (26%), Positives = 113/279 (40%), Gaps = 32/279 (11%)
Query: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
LP+ C PP++ + + + +F + Y CE + + G S+ C WS
Sbjct: 1640 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGY-DLRGAA-SLHCTPQGDWS 1697
Query: 89 DIEEFCN-RSC-EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYR-REPSLSPKLTC 145
C +SC + +L + P Q +G V + C G+R + S+S +
Sbjct: 1698 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQ----LGAKVSFVCDEGFRLKGSSVSHCVLV 1753
Query: 146 LQNLKWSTAVEFCKKKSCPNPGEIRNGQ-IDVPGG-ILFGATISFSCN------TGYKLF 197
W+ +V C+ CPNP I NG+ P G I +G IS++C+ + L
Sbjct: 1754 GMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLI 1813
Query: 198 GSTSSFCLIS--GSSVQWSDPLPEC----REIYCPAPPQID--NGIIQGERDHYGYRQSV 249
G ++ C G+ V WS P P C R +C P Q + I + S+
Sbjct: 1814 GESTIRCTSDPHGNGV-WSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSL 1872
Query: 250 TYACNKGFTMIGE-HSIYCTVNNDEGEWSGPPPECRGKS 287
Y C G+ G+ SI C N WS CR KS
Sbjct: 1873 NYECRPGY--FGKMFSISCLENL---VWSSVEDNCRRKS 1906
>gi|86793036 complement receptor 1 isoform F precursor [Homo
sapiens]
Length = 2039
Score = 168 bits (426), Expect = 8e-42
Identities = 101/268 (37%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEE------SFVKIPGEKDSVICLKGSQ--- 86
C PP +PN + + FP + Y C+ SF I GE ++ C Q
Sbjct: 421 CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLI-GES-TIRCTSDPQGNG 478
Query: 87 -WSDIEEFCN--RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKL 143
WS C C+ P A LK + FP+GT ++YECRP Y P +
Sbjct: 479 VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYYGRPF---SI 534
Query: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
TCL NL WS+ + CK+KSC P + NG + V I G+ I++SC TG++L G +S+
Sbjct: 535 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 594
Query: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG------ 256
C++SG++ WS P C+ I C PP I NG I R+++ Y VTY CN G
Sbjct: 595 CILSGNAAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKV 654
Query: 257 FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 655 FELVGEPSIYCTSNDDQVGIWSGPAPQC 682
Score = 168 bits (425), Expect = 1e-41
Identities = 101/268 (37%), Positives = 139/268 (51%), Gaps = 26/268 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEE------SFVKIPGEKDSVICLKGSQ--- 86
C PP +PN + + FP + Y C+ SF I GE ++ C Q
Sbjct: 871 CPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLI-GES-TIRCTSDPQGNG 928
Query: 87 -WSDIEEFCN--RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKL 143
WS C C+ P A LK + FP+GT ++YECRP Y P +
Sbjct: 929 VWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYYGRPF---SI 984
Query: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
TCL NL WS+ + CK+KSC P + NG + V I G+ I++SC TG++L G +S+
Sbjct: 985 TCLDNLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAE 1044
Query: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG------ 256
C++SG++ WS P C+ I C PP I NG I R+++ Y VTY CN G
Sbjct: 1045 CILSGNTAHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKV 1104
Query: 257 FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 1105 FELVGEPSIYCTSNDDQVGIWSGPAPQC 1132
Score = 162 bits (410), Expect = 6e-40
Identities = 80/173 (46%), Positives = 106/173 (61%), Gaps = 11/173 (6%)
Query: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPG 178
FP+GT + YECRPGY P + CL+N W+ A + C++KSC NP + NG + V
Sbjct: 63 FPIGTYLNYECRPGYSGRPF---SIICLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIK 119
Query: 179 GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQ 237
GI FG+ I +SC GY+L GS+S+ C+ISG +V W + P C I C PP I NG I
Sbjct: 120 GIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFIS 179
Query: 238 GERDHYGYRQSVTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
R+++ Y VTY CN G F ++GE SIYCT N+D+ G WSGP P+C
Sbjct: 180 TNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232
Score = 155 bits (391), Expect = 9e-38
Identities = 95/270 (35%), Positives = 131/270 (48%), Gaps = 27/270 (10%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEES-----FVKIPGEKDSVICLKGSQ---- 86
C PP + N + P I+Y C+ + GE ++ C
Sbjct: 1321 CPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGES-TIRCTSDPHGNGV 1379
Query: 87 WSDIEEFCNRS-----CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSP 141
WS C S C+ P + AS P I FPVGT + YECRPGY +
Sbjct: 1380 WSSPAPRCELSVRAGHCKTPEQFPFASPTIP-INDFEFPVGTSLNYECRPGYFGKMF--- 1435
Query: 142 KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTS 201
++CL+NL WS+ + C++KSC P E NG + + FG+T+++SCN G++L GS S
Sbjct: 1436 SISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPS 1495
Query: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG---- 256
+ CL+SG++V W P C I C PP I NG R + VTY C+ G
Sbjct: 1496 TTCLVSGNNVTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGE 1555
Query: 257 --FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
F ++GE SIYCT +D+ G WS PPP C
Sbjct: 1556 QLFELVGERSIYCTSKDDQVGVWSSPPPRC 1585
Score = 136 bits (342), Expect = 4e-32
Identities = 80/254 (31%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 297
Query: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
+ P + A Q ++ F G V Y C PGY + S + C WS A C
Sbjct: 298 QPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGAAS--MRCTPQGDWSPAAPTC 353
Query: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
+ KSC + G++ NG++ P + GA + F C+ G++L GS++S+C+++G W+ +
Sbjct: 354 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 413
Query: 218 PECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
P C +I+CP+PP I NG G+ + + + ++V Y C+ F +IGE +I CT +
Sbjct: 414 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSD 473
Query: 271 -NDEGEWSGPPPEC 283
G WS P P C
Sbjct: 474 PQGNGVWSSPAPRC 487
Score = 136 bits (342), Expect = 4e-32
Identities = 80/254 (31%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 690 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 747
Query: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
+ P + A Q ++ F G V Y C PGY + S + C WS A C
Sbjct: 748 QPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGAAS--MRCTPQGDWSPAAPTC 803
Query: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
+ KSC + G++ NG++ P + GA + F C+ G++L GS++S+C+++G W+ +
Sbjct: 804 EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 863
Query: 218 PECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
P C +I+CP+PP I NG G+ + + + ++V Y C+ F +IGE +I CT +
Sbjct: 864 PVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSD 923
Query: 271 -NDEGEWSGPPPEC 283
G WS P P C
Sbjct: 924 PQGNGVWSSPAPRC 937
Score = 127 bits (320), Expect = 2e-29
Identities = 78/253 (30%), Positives = 120/253 (47%), Gaps = 15/253 (5%)
Query: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCE 99
P+V NA R+ F +I ++C+ FV + +V C +W C+R C+
Sbjct: 1594 PEVENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSH--TVQCQTNGRWGPKLPHCSRVCQ 1651
Query: 100 VPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCK 159
P + + Q+ F G V Y C P Y + S L C WS C
Sbjct: 1652 PPPEILHGEHTLSH--QDNFSPGQEVFYSCEPSYDLRGAAS--LHCTPQGDWSPEAPRCT 1707
Query: 160 KKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLP 218
KSC + G++ +G++ +P + GA +SF C+ G++L G ++S C+++G W+ +P
Sbjct: 1708 VKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSVP 1767
Query: 219 ECREIYCPAPPQIDNGIIQGER-DHYGYRQSVTYACN------KGFTMIGEHSIYCTVN- 270
C +I+CP PP I NG G Y + ++YAC+ F +IGE SI CT +
Sbjct: 1768 VCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDP 1827
Query: 271 NDEGEWSGPPPEC 283
G WS P P C
Sbjct: 1828 QGNGVWSSPAPRC 1840
Score = 125 bits (313), Expect = 1e-28
Identities = 79/254 (31%), Positives = 123/254 (48%), Gaps = 15/254 (5%)
Query: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSC 98
PP+V N + R+ F + V+ ++C+ FV + G + V C ++W C+R C
Sbjct: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFV-MKGPR-RVKCQALNKWEPELPSCSRVC 1197
Query: 99 EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFC 158
+ P + + Q+ F G V Y C PGY + S L C WS C
Sbjct: 1198 QPPPEILHGEHTPSH--QDNFSPGQEVFYSCEPGYDLRGAAS--LHCTPQGDWSPEAPRC 1253
Query: 159 KKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
KSC + G++ +G++ P + GA +SF C+ G++L GS+ S C++ G W++ +
Sbjct: 1254 AVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSV 1313
Query: 218 PECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACN------KGFTMIGEHSIYCTVN 270
P C I+CP PP I NG G Y + ++Y C+ F +IGE +I CT +
Sbjct: 1314 PVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSD 1373
Query: 271 -NDEGEWSGPPPEC 283
+ G WS P P C
Sbjct: 1374 PHGNGVWSSPAPRC 1387
Score = 115 bits (288), Expect = 8e-26
Identities = 84/291 (28%), Positives = 125/291 (42%), Gaps = 30/291 (10%)
Query: 21 LLLLVLLCLPAVWGDCGLPPDVPNAQPA-LEGRTSFPEDTVITYKCEESFVKIPGEKDSV 79
L ++VLL LP WG C P +P A+P L FP T + Y+C + G S+
Sbjct: 28 LAVVVLLALPVAWGQCNAPEWLPFARPTNLTDEFEFPIGTYLNYECRPGY---SGRPFSI 84
Query: 80 ICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPS 138
ICLK S W+ ++ C R SC P + + ++ + G+ ++Y C GYR S
Sbjct: 85 ICLKNSVWTGAKDRCRRKSCRNPPDPVNGMV---HVIKG-IQFGSQIKYSCTKGYRLIGS 140
Query: 139 LSPKLTCL---QNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG 193
S TC+ + W C + C P I NG +G+ +++ CN G
Sbjct: 141 SS--ATCIISGDTVIWDNETPICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPG 198
Query: 194 ------YKLFGSTSSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGI-IQGERDHYGY 245
++L G S +C + V WS P P+C PP ++NGI + R +
Sbjct: 199 SGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSL 258
Query: 246 RQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
+ V + C GF M G + C N +W P C S + PP V
Sbjct: 259 NEVVEFRCQPGFVMKGPRRVKCQALN---KWEPELPSC---SRVCQPPPDV 303
Score = 114 bits (284), Expect = 2e-25
Identities = 80/278 (28%), Positives = 115/278 (41%), Gaps = 30/278 (10%)
Query: 34 GDCGLPPDVPNAQPALE-GRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEE 92
G C P P A P + FP T + Y+C + G+ S+ CL+ WS +E+
Sbjct: 1394 GHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYF---GKMFSISCLENLVWSSVED 1450
Query: 93 FCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCL---QN 148
C R SC P + + TQ G+ V Y C G+R S P TCL N
Sbjct: 1451 NCRRKSCGPPPEPFNGMVHINTDTQ----FGSTVNYSCNEGFRLIGS--PSTTCLVSGNN 1504
Query: 149 LKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF--GATISFSCNTG------YKLFGST 200
+ W C+ SC P I NG F G +++ C+TG ++L G
Sbjct: 1505 VTWDKKAPICEIISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQLFELVGER 1564
Query: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGI-IQGERDHYGYRQSVTYACNKGFT 258
S +C V WS P P C P+++N I + G R + + + + C GF
Sbjct: 1565 SIYCTSKDDQVGVWSSPPPRCISTNKCTAPEVENAIRVPGNRSFFTLTEIIRFRCQPGFV 1624
Query: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
M+G H++ C N G W P C S + PP +
Sbjct: 1625 MVGSHTVQCQTN---GRWGPKLPHC---SRVCQPPPEI 1656
Score = 94.0 bits (232), Expect = 2e-19
Identities = 78/266 (29%), Positives = 122/266 (45%), Gaps = 27/266 (10%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
C PP++ + + L + +F + Y CE S+ + G S+ C WS C
Sbjct: 1650 CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSY-DLRGAA-SLHCTPQGDWSPEAPRCT 1707
Query: 96 -RSC-EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYR-REPSLSPKLTCLQNLKWS 152
+SC + +L + P Q +G V + C G+R + S S + W+
Sbjct: 1708 VKSCDDFLGQLPHGRVLLPLNLQ----LGAKVSFVCDEGFRLKGRSASHCVLAGMKALWN 1763
Query: 153 TAVEFCKKKSCPNPGEIRNGQ-IDVP-GGILFGATISFSCNT------GYKLFGSTSSFC 204
++V C++ CPNP I NG+ P G I +G IS++C+T + L G +S C
Sbjct: 1764 SSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGESSIRC 1823
Query: 205 LI--SGSSVQWSDPLPECR---EIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKGFT 258
G+ V WS P P C CP PP+I NG I G Y +++Y C+ G+
Sbjct: 1824 TSDPQGNGV-WSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYL 1882
Query: 259 MIGEHSIYCTVNNDEGEWSGPPPECR 284
++G+ I+CT D+G WS C+
Sbjct: 1883 LVGKGFIFCT---DQGIWSQLDHYCK 1905
Score = 90.1 bits (222), Expect = 4e-18
Identities = 75/278 (26%), Positives = 113/278 (40%), Gaps = 26/278 (9%)
Query: 32 VWGDCGLPPDVPNAQPALEGRTS-FPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI 90
+ G C P A+ + S FP T + Y+C + G S+ CL WS
Sbjct: 489 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY---GRPFSITCLDNLVWSSP 545
Query: 91 EEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL 149
++ C R SC+ P + + IT VG+ + Y C G+R S + N
Sbjct: 546 KDVCKRKSCKTPPDPVNGMVH--VITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNA 601
Query: 150 K-WSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG------YKLFGST 200
WST C++ C P I NG +G+ +++ CN G ++L G
Sbjct: 602 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEP 661
Query: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACNKGFT 258
S +C + V WS P P+C PP ++NGI+ + R + + V + C GF
Sbjct: 662 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 721
Query: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
M G + C N +W P C S + PP V
Sbjct: 722 MKGPRRVKCQALN---KWEPELPSC---SRVCQPPPDV 753
Score = 89.7 bits (221), Expect = 5e-18
Identities = 74/278 (26%), Positives = 113/278 (40%), Gaps = 26/278 (9%)
Query: 32 VWGDCGLPPDVPNAQPALEGRTS-FPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDI 90
+ G C P A+ + S FP T + Y+C + G S+ CL WS
Sbjct: 939 ILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYY---GRPFSITCLDNLVWSSP 995
Query: 91 EEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL 149
++ C R SC+ P + + IT VG+ + Y C G+R S + N
Sbjct: 996 KDVCKRKSCKTPPDPVNGMVH--VITD--IQVGSRINYSCTTGHRLIGHSSAECILSGNT 1051
Query: 150 K-WSTAVEFCKKKSCPNPGEIRNGQIDVPG--GILFGATISFSCNTG------YKLFGST 200
WST C++ C P I NG +G+ +++ CN G ++L G
Sbjct: 1052 AHWSTKPPICQRIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKVFELVGEP 1111
Query: 201 SSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGIIQGE-RDHYGYRQSVTYACNKGFT 258
S +C + V WS P P+C PP ++NGI+ + R + + V + C GF
Sbjct: 1112 SIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFV 1171
Query: 259 MIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
M G + C N +W P C S + PP +
Sbjct: 1172 MKGPRRVKCQALN---KWEPELPSC---SRVCQPPPEI 1203
Score = 83.6 bits (205), Expect = 3e-16
Identities = 74/267 (27%), Positives = 109/267 (40%), Gaps = 28/267 (10%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ--WSDIEEF 93
CG PP+ N + T F + + Y C E F ++ G + + G+ W
Sbjct: 1457 CGPPPEPFNGMVHINTDTQF--GSTVNYSCNEGF-RLIGSPSTTCLVSGNNVTWDKKAPI 1513
Query: 94 CNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCL-- 146
C SCE P +++ T F GTVV Y+C G E + C
Sbjct: 1514 CEIISCEPPPTISNGDFYSNNRTS--FHNGTVVTYQCHTGPDGEQLFELVGERSIYCTSK 1571
Query: 147 --QNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGAT---ISFSCNTGYKLFGSTS 201
Q WS+ C + E+ N I VPG F I F C G+ + GS +
Sbjct: 1572 DDQVGVWSSPPPRCISTNKCTAPEVENA-IRVPGNRSFFTLTEIIRFRCQPGFVMVGSHT 1630
Query: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGI-IQGERDHYGYRQSVTYACNKGFTMI 260
C +G +W LP C + C PP+I +G +D++ Q V Y+C + +
Sbjct: 1631 VQCQTNG---RWGPKLPHCSRV-CQPPPEILHGEHTLSHQDNFSPGQEVFYSCEPSYDLR 1686
Query: 261 GEHSIYCTVNNDEGEWSGPPPECRGKS 287
G S++CT +G+WS P C KS
Sbjct: 1687 GAASLHCT---PQGDWSPEAPRCTVKS 1710
Score = 67.8 bits (164), Expect = 2e-11
Identities = 78/288 (27%), Positives = 123/288 (42%), Gaps = 41/288 (14%)
Query: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
LP+ C PPDV +A+ + +F + Y CE + + G S+ C WS
Sbjct: 290 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY-DLRGAA-SMRCTPQGDWS 347
Query: 89 DIEEFCN-RSCE--VPTRLNSASLKQPYITQNYFPV----GTVVEYECRPGYRREPSLSP 141
C +SC+ + LN L FPV G V++ C G++ + S +
Sbjct: 348 PAAPTCEVKSCDDFMGQLLNGRVL---------FPVNLQLGAKVDFVCDEGFQLKGSSAS 398
Query: 142 --KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ-IDVPGGIL-FGATISFSCN------ 191
L +++L W+++V C++ CP+P I NG+ P + FG T++++C+
Sbjct: 399 YCVLAGMESL-WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRG 457
Query: 192 TGYKLFGSTSSFCLI--SGSSVQWSDPLPECREI-YCPAPPQIDNGII--QGERDHYGYR 246
T + L G ++ C G+ V WS P P C + +C AP + Q +
Sbjct: 458 TSFDLIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIG 516
Query: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP 294
S+ Y C + SI C D WS P C+ KS K PP
Sbjct: 517 TSLKYECRPEY-YGRPFSITCL---DNLVWSSPKDVCKRKS--CKTPP 558
Score = 65.9 bits (159), Expect = 7e-11
Identities = 77/288 (26%), Positives = 122/288 (42%), Gaps = 41/288 (14%)
Query: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
LP+ C PPDV +A+ + +F + Y CE + + G S+ C WS
Sbjct: 740 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY-DLRGAA-SMRCTPQGDWS 797
Query: 89 DIEEFCN-RSCE--VPTRLNSASLKQPYITQNYFPV----GTVVEYECRPGYRREPSLSP 141
C +SC+ + LN L FPV G V++ C G++ + S +
Sbjct: 798 PAAPTCEVKSCDDFMGQLLNGRVL---------FPVNLQLGAKVDFVCDEGFQLKGSSAS 848
Query: 142 --KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ-IDVPGGIL-FGATISFSCN------ 191
L +++L W+++V C++ CP+P I NG+ P + FG ++++C+
Sbjct: 849 YCVLAGMESL-WNSSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRG 907
Query: 192 TGYKLFGSTSSFCLI--SGSSVQWSDPLPECREI-YCPAPPQIDNGII--QGERDHYGYR 246
T + L G ++ C G+ V WS P P C + +C AP + Q +
Sbjct: 908 TSFDLIGESTIRCTSDPQGNGV-WSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIG 966
Query: 247 QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP 294
S+ Y C + SI C D WS P C+ KS K PP
Sbjct: 967 TSLKYECRPEY-YGRPFSITCL---DNLVWSSPKDVCKRKS--CKTPP 1008
Score = 65.5 bits (158), Expect = 9e-11
Identities = 67/269 (24%), Positives = 101/269 (37%), Gaps = 33/269 (12%)
Query: 49 LEGRTSFPED----TVITYKCEESFVKIPGEKDSVICLKG--SQWSDIEEFCNRS-CEVP 101
L GR FP + + + C+E F ++ G S L G S W+ C + C P
Sbjct: 366 LNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSP 424
Query: 102 TRL-NSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWS 152
+ N +P FP G V Y C P R S + C N WS
Sbjct: 425 PVIPNGRHTGKPL---EVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 481
Query: 153 TAVEFCKKKS-CPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISG 208
+ C C P ++ G ++ + C Y +G S +
Sbjct: 482 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD- 538
Query: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKGFTMIGEHSIYC 267
++ WS P C+ C PP NG++ D G R + Y+C G +IG S C
Sbjct: 539 -NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSR--INYSCTTGHRLIGHSSAEC 595
Query: 268 TVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
++ + WS PP C + + +PPT+
Sbjct: 596 ILSGNAAHWSTKPPIC--QRIPCGLPPTI 622
Score = 65.5 bits (158), Expect = 9e-11
Identities = 67/269 (24%), Positives = 101/269 (37%), Gaps = 33/269 (12%)
Query: 49 LEGRTSFPED----TVITYKCEESFVKIPGEKDSVICLKG--SQWSDIEEFCNRS-CEVP 101
L GR FP + + + C+E F ++ G S L G S W+ C + C P
Sbjct: 816 LNGRVLFPVNLQLGAKVDFVCDEGF-QLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSP 874
Query: 102 TRL-NSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWS 152
+ N +P FP G V Y C P R S + C N WS
Sbjct: 875 PVIPNGRHTGKPL---EVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNGVWS 931
Query: 153 TAVEFCKKKS-CPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISG 208
+ C C P ++ G ++ + C Y +G S +
Sbjct: 932 SPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEY--YGRPFSITCLD- 988
Query: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKGFTMIGEHSIYC 267
++ WS P C+ C PP NG++ D G R + Y+C G +IG S C
Sbjct: 989 -NLVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSR--INYSCTTGHRLIGHSSAEC 1045
Query: 268 TVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
++ + WS PP C + + +PPT+
Sbjct: 1046 ILSGNTAHWSTKPPIC--QRIPCGLPPTI 1072
Score = 62.4 bits (150), Expect = 8e-10
Identities = 64/247 (25%), Positives = 100/247 (40%), Gaps = 32/247 (12%)
Query: 61 ITYKCEESFVKIPGEKDSVICLKGSQ--WSDIEEFCNRSC--EVPTRLNSASLKQPYITQ 116
+++ C+E F ++ G S L G + W+ C + P LN P+
Sbjct: 1735 VSFVCDEGF-RLKGRSASHCVLAGMKALWNSSVPVCEQIFCPNPPAILNGRHTGTPF--- 1790
Query: 117 NYFPVGTVVEYECRPGYRREPSLS----PKLTCLQ----NLKWSTAVEFCKKK---SCPN 165
P G + Y C R + + + C N WS+ C+ +CP+
Sbjct: 1791 GDIPYGKEISYACDTHPDRGMTFNLIGESSIRCTSDPQGNGVWSSPAPRCELSVPAACPH 1850
Query: 166 PGEIRNGQIDVPGGI---LFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECRE 222
P +I+NG + G + L G TIS+ C+ GY L G FC G WS C+E
Sbjct: 1851 PPKIQNGHY-IGGHVSLYLPGMTISYICDPGYLLVGKGFIFCTDQGI---WSQLDHYCKE 1906
Query: 223 IYCPAPPQIDNGIIQ--GERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
+ C + P NGI + + Y Y VT C G+T+ G C ++ W P
Sbjct: 1907 VNC-SFPLFMNGISKELEMKKVYHYGDYVTLKCEDGYTLEGSPWSQCQADD---RWDPPL 1962
Query: 281 PECRGKS 287
+C ++
Sbjct: 1963 AKCTSRT 1969
Score = 61.6 bits (148), Expect = 1e-09
Identities = 74/279 (26%), Positives = 113/279 (40%), Gaps = 32/279 (11%)
Query: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
LP+ C PP++ + + + +F + Y CE + + G S+ C WS
Sbjct: 1190 LPSCSRVCQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGY-DLRGAA-SLHCTPQGDWS 1247
Query: 89 DIEEFCN-RSC-EVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYR-REPSLSPKLTC 145
C +SC + +L + P Q +G V + C G+R + S+S +
Sbjct: 1248 PEAPRCAVKSCDDFLGQLPHGRVLFPLNLQ----LGAKVSFVCDEGFRLKGSSVSHCVLV 1303
Query: 146 LQNLKWSTAVEFCKKKSCPNPGEIRNGQ-IDVPGG-ILFGATISFSCN------TGYKLF 197
W+ +V C+ CPNP I NG+ P G I +G IS++C+ + L
Sbjct: 1304 GMRSLWNNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLI 1363
Query: 198 GSTSSFCLIS--GSSVQWSDPLPEC----REIYCPAPPQID--NGIIQGERDHYGYRQSV 249
G ++ C G+ V WS P P C R +C P Q + I + S+
Sbjct: 1364 GESTIRCTSDPHGNGV-WSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSL 1422
Query: 250 TYACNKGFTMIGE-HSIYCTVNNDEGEWSGPPPECRGKS 287
Y C G+ G+ SI C N WS CR KS
Sbjct: 1423 NYECRPGY--FGKMFSISCLENL---VWSSVEDNCRRKS 1456
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 155 bits (392), Expect = 7e-38
Identities = 89/222 (40%), Positives = 123/222 (55%), Gaps = 21/222 (9%)
Query: 71 KIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNY-FPVGTVVEYEC 129
+ PG + + L S +SD C VP L A + +T ++ FP+GT + YEC
Sbjct: 15 RFPGLLLAALVLLLSSFSD-------QCNVPEWLPFA--RPTNLTDDFEFPIGTYLNYEC 65
Query: 130 RPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFS 189
RPGY P + CL+N W++A + CK+KSC NP + NG V I F + I +S
Sbjct: 66 RPGYSGRPF---SIICLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQFRSQIKYS 122
Query: 190 CNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQG-ERDHYGYRQS 248
C GY+L GS+S+ C+ISG++V W + P C I C PP I NG R+++ Y
Sbjct: 123 CPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGSV 182
Query: 249 VTYACNKG------FTMIGEHSIYCTVNNDE-GEWSGPPPEC 283
VTY CN G F ++GE SIYCT +D+ G WSGP P+C
Sbjct: 183 VTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQC 224
Score = 127 bits (318), Expect = 3e-29
Identities = 90/320 (28%), Positives = 140/320 (43%), Gaps = 34/320 (10%)
Query: 39 PPDVPNAQPALEGRTSFPEDTVITYKCEESF-VKIPGEKDSVICLKGSQWSDIEEFCNRS 97
PP+V N + R+ F + V+ ++C+ F +K P V C ++W C+R
Sbjct: 232 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSH---VKCQALNKWEPELPSCSRV 288
Query: 98 CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEF 157
C+ P + A Q ++ F G V Y C PGY S L C WS A
Sbjct: 289 CQPPPDVLHAERTQR--DKDNFSPGQEVFYSCEPGYDLRGSTY--LHCTPQGDWSPAAPR 344
Query: 158 CKKKSCPN-PGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDP 216
C+ KSC + G++ NG + P + GA + F C+ G++L GS++S+C+++G W+
Sbjct: 345 CEVKSCDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSS 404
Query: 217 LPECREIYCPAPPQIDNGIIQGERD-HYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
+P C C PP NG++ D H G R + Y+C G +IG S C ++ +
Sbjct: 405 VPVCERKSCETPPVPVNGMVHVITDIHVGSR--INYSCTTGHRLIGHSSAECILSGNTAH 462
Query: 276 WSGPPPECRGKSLTSKVPPTVQKPTTVNVPT------TEVSPT--------------SQK 315
WS PP C + + PP + P EVS T +
Sbjct: 463 WSMKPPIC--QQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGES 520
Query: 316 TTTKTTTPNAQATRSTPVSR 335
T +T+ P+ S+P R
Sbjct: 521 TIRRTSEPHGNGVWSSPAPR 540
Score = 114 bits (286), Expect = 1e-25
Identities = 81/267 (30%), Positives = 131/267 (49%), Gaps = 19/267 (7%)
Query: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
LP+ C PPDV +A+ + +F + Y CE + + G + C WS
Sbjct: 282 LPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGY-DLRGST-YLHCTPQGDWS 339
Query: 89 DIEEFCN-RSCE-VPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPK--LT 144
C +SC+ +L + + P Q +G V++ C G++ + S + L
Sbjct: 340 PAAPRCEVKSCDDFLGQLPNGHVLFPLNLQ----LGAKVDFVCDEGFQLKGSSASYCVLA 395
Query: 145 CLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFC 204
+++L W+++V C++KSC P NG + V I G+ I++SC TG++L G +S+ C
Sbjct: 396 GMESL-WNSSVPVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAEC 454
Query: 205 LISGSSVQWSDPLPECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACN------KGF 257
++SG++ WS P C++I+CP PP I NG G Y + V+Y C+ F
Sbjct: 455 ILSGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTF 514
Query: 258 TMIGEHSIYCTVN-NDEGEWSGPPPEC 283
+IGE +I T + G WS P P C
Sbjct: 515 NLIGESTIRRTSEPHGNGVWSSPAPRC 541
Score = 79.7 bits (195), Expect = 5e-15
Identities = 64/265 (24%), Positives = 103/265 (38%), Gaps = 24/265 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ--WSDIEEF 93
C PPD N + F I Y C + + ++ G + + G+ W +
Sbjct: 96 CRNPPDPVNGMAHVIKDIQFRSQ--IKYSCPKGY-RLIGSSSATCIISGNTVIWDNKTPV 152
Query: 94 CNRS-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLS----PKLTCLQN 148
C+R C +P + + I++ YF G+VV Y C G R + P + C
Sbjct: 153 CDRIICGLPPTIANGDFTS--ISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSK 210
Query: 149 LK----WSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGAT--ISFSCNTGYKLFGSTSS 202
WS C + P + NG + LF + F C G+ + G +
Sbjct: 211 DDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHV 270
Query: 203 FCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGE 262
C +W LP C + P P + Q ++D++ Q V Y+C G+ + G
Sbjct: 271 KCQALN---KWEPELPSCSRVCQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGS 327
Query: 263 HSIYCTVNNDEGEWSGPPPECRGKS 287
++CT +G+WS P C KS
Sbjct: 328 TYLHCT---PQGDWSPAAPRCEVKS 349
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 154 bits (390), Expect = 1e-37
Identities = 80/198 (40%), Positives = 113/198 (57%), Gaps = 5/198 (2%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVE 156
+C P L+ A+ +T+ F GT ++Y C PGY R S + LTC + +W
Sbjct: 49 NCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHS-TQTLTCNSDGEWVYNT- 106
Query: 157 FCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDP 216
FC K C +PGE+RNGQ+++ + FG+ I FSC+ G+ L GST+S C + V WS P
Sbjct: 107 FCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHP 166
Query: 217 LPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDE-GE 275
LP+C + C PP I NG GE + Y Y SVTY+C+ F+++G SI CTV N+ G
Sbjct: 167 LPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGV 226
Query: 276 WSGPPPECRGKSLTSKVP 293
W PP C + +T + P
Sbjct: 227 WRPSPPTC--EKITCRKP 242
Score = 103 bits (256), Expect = 4e-22
Identities = 70/239 (29%), Positives = 115/239 (48%), Gaps = 28/239 (11%)
Query: 57 EDTVITYKCEESFVKIPGEKDSVI-CLKGSQWSDIEEFC--NRSCEVPTRLNSASLKQPY 113
+DT++ +KC++ FV SVI C S+W+ C N +P +++ P
Sbjct: 260 KDTIV-FKCQKGFVL---RGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPR 315
Query: 114 IT-QNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNP----GE 168
T ++ + VGTV+ Y C PGY+ + C +NL+W T + C+ CP P GE
Sbjct: 316 PTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRW-TPYQGCEALCCPEPKLNNGE 374
Query: 169 IRNGQIDVPGG---ILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYC 225
I + P +G ISFSC+ TS F I WS P C +I C
Sbjct: 375 ITQHRKSRPANHCVYFYGDEISFSCH-------ETSRFSAICQGDGTWSPRTPSCGDI-C 426
Query: 226 PAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
PP+I +G + + +++ + Y C+KG+ ++G+ + C+ ++ WS P P+C+
Sbjct: 427 NFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSH----WSAPAPQCK 481
Score = 101 bits (252), Expect = 1e-21
Identities = 67/272 (24%), Positives = 118/272 (43%), Gaps = 15/272 (5%)
Query: 22 LLLVLLCLPAVWGDCGLPPDVPNAQPA--LEGRTSFPEDTVITYKCEESFVKIPGEKDSV 79
+ L+ LPAV G+CG PP + A P T F T + Y C +V+ + ++
Sbjct: 36 MTLIAALLPAVLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQ-TL 94
Query: 80 ICLKGSQWSDIEEFC-NRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPS 138
C +W FC + C P L + ++ + G+ +E+ C G+ S
Sbjct: 95 TCNSDGEWV-YNTFCIYKRCRHPGELRNGQVE----IKTDLSFGSQIEFSCSEGFFLIGS 149
Query: 139 LSPKLTCL-QNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKL 196
+ + + + WS + C+ C P +IRNG+ +G ++++SC+ + L
Sbjct: 150 TTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSL 209
Query: 197 FGSTSSFCLISGSSVQ-WSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNK 255
G S C + ++ W P C +I C P ++ G Y Y+ ++ + C K
Sbjct: 210 LGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQK 269
Query: 256 GFTMIGEHSIYCTVNNDEGEWSGPPPECRGKS 287
GF + G I+C + + +W+ PP C S
Sbjct: 270 GFVLRGSSVIHC---DADSKWNPSPPACEPNS 298
Score = 79.3 bits (194), Expect = 6e-15
Identities = 65/254 (25%), Positives = 101/254 (39%), Gaps = 28/254 (11%)
Query: 40 PDVPNAQ----PALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
PD+P+A P + TV+ Y+C + E +VIC K +W+ + C
Sbjct: 303 PDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQG-CE 361
Query: 96 RSCEVPTRLNSASLKQ-----PYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
C +LN+ + Q P YF G + + C R C +
Sbjct: 362 ALCCPEPKLNNGEITQHRKSRPANHCVYF-YGDEISFSCHETSRFSA------ICQGDGT 414
Query: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVPGGI-LFGATISFSCNTGYKLFGSTSSFCLISGS 209
WS C C P +I +G F I + C+ GY L G C S
Sbjct: 415 WSPRTPSCGD-ICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYS-- 471
Query: 210 SVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTV 269
WS P P+C+ + P++ NG + ++D Y ++VT C+ G+ ++G SI C+
Sbjct: 472 --HWSAPAPQCKALC--RKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSG 527
Query: 270 NNDEGEWSGPPPEC 283
N W P+C
Sbjct: 528 NR---TWYPEVPKC 538
Score = 46.2 bits (108), Expect = 6e-05
Identities = 48/186 (25%), Positives = 72/186 (38%), Gaps = 12/186 (6%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
C P + N + ++ V Y E SF + S IC WS C
Sbjct: 364 CCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSAICQGDGTWSPRTPSCG 423
Query: 96 RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
C P ++ KQ + +Y + YEC GY KL+C + WS
Sbjct: 424 DICNFPPKIAHGHYKQ---SSSYSFFKEEIIYECDKGYILVG--QAKLSCSYS-HWSAPA 477
Query: 156 EFCKKKSCPNPGEIRNGQIDV-PGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
C K C P E+ NG++ V + ++ C++GY + G S C SG+ W
Sbjct: 478 PQC-KALCRKP-ELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITC--SGNRT-WY 532
Query: 215 DPLPEC 220
+P+C
Sbjct: 533 PEVPKC 538
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 119 bits (297), Expect = 7e-27
Identities = 82/263 (31%), Positives = 123/263 (46%), Gaps = 33/263 (12%)
Query: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCE 99
P VP + G T + +T+ C+ +F + G K SV C + W
Sbjct: 94 PIVPGGYK-IRGSTPYRHGDSVTFACKTNF-SMNGNK-SVWCQANNMWGPTR-------- 142
Query: 100 VPTRLNSASLKQP---------YITQNYFPV--GTVVEYECRPGYRREPSLSPKLTCLQN 148
+PT ++ L+ P + ++N + G V Y C GY + CL +
Sbjct: 143 LPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI--INCLSS 200
Query: 149 LKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISG 208
KWS C++ C + G NG++ P + G T +F C+ GY+L G SS C+I+G
Sbjct: 201 GKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAG 260
Query: 209 SSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNK------GFTMIG 261
V W+ +P C EI+CP+PP I NG I + Y VTY C+ F +IG
Sbjct: 261 QGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIG 319
Query: 262 EHSIYCTVNNDE-GEWSGPPPEC 283
E ++ CTV++ + G WSGP P C
Sbjct: 320 ESTLRCTVDSQKTGTWSGPAPRC 342
Score = 107 bits (268), Expect = 2e-23
Identities = 73/277 (26%), Positives = 123/277 (44%), Gaps = 28/277 (10%)
Query: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
+C P + N E S +TY CE ++ + GEK + CL +WS + C
Sbjct: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV-GEK-IINCLSSGKWSAVPPTC 210
Query: 95 NRS-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRRE-PSLSPKLTCLQNLKWS 152
+ C+ R + +K+P I + VG + C GYR + P S + Q + W
Sbjct: 211 EEARCKSLGRFPNGKVKEPPILR----VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAW- 265
Query: 153 TAVEFCKKKSCPNPGEIRNGQI--DVPGGILFGATISFSCN------TGYKLFGSTSSFC 204
T + C++ CP+P I NG+ + + +G+ ++++C+ + L G ++ C
Sbjct: 266 TKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRC 325
Query: 205 LISGSSV-QWSDPLPECR----EIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTM 259
+ WS P P C + CP P + ++ G++D Y Y +V +AC GFT+
Sbjct: 326 TVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL 385
Query: 260 IGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
G I C N +G W P C + + PP +
Sbjct: 386 KGSKQIRC---NAQGTWEPSAPVCEKE---CQAPPNI 416
Score = 92.8 bits (229), Expect = 5e-19
Identities = 79/269 (29%), Positives = 118/269 (43%), Gaps = 30/269 (11%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ----WSDIE 91
C PP + N + +F ++Y+C++ F + GEK + C S+ WS
Sbjct: 719 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEK-KLQCRSDSKGHGSWSGPS 776
Query: 92 EFCNRSCEVPTRLNSASLKQPYI---TQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQN 148
C RS V TR + +K Y T + + +V +C PG+ S + C +
Sbjct: 777 PQCLRSPPV-TRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV--IRCHTD 833
Query: 149 LKWSTAVEFCKKKS---CPNPGEIRNGQIDVPGGILF----GATISFSCNTGYKLFGSTS 201
W V C KK+ CP P + NG + GG + G +I +SC+ GY L G
Sbjct: 834 NTWVPGVPTCIKKAFIGCPPPPKTPNG--NHTGGNIARFSPGMSILYSCDQGYLLVGEAL 891
Query: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQG--ERDHYGYRQSVTYACNKGFTM 259
C G+ WS P P C+E+ C +P +D GI +G R Y Y VT C G+ +
Sbjct: 892 LLCTHEGT---WSQPAPHCKEVNCSSPADMD-GIQKGLEPRKMYQYGAVVTLECEDGYML 947
Query: 260 IGEHSIYCTVNNDEGEWSGPPPECRGKSL 288
G C + +W+ P CR +SL
Sbjct: 948 EGSPQSQC---QSDHQWNPPLAVCRSRSL 973
Score = 92.0 bits (227), Expect = 9e-19
Identities = 71/272 (26%), Positives = 117/272 (43%), Gaps = 23/272 (8%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCE---ESFVKIPGEKDSVI-CLKGSQ----W 87
C PP + N FP T +TY C E V+ +S I C Q W
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 88 SDIEEFCNRSCEVPTRLNSASLKQPYITQN----YFPVGTVVEYECRPGYRREPSLSPKL 143
S C S + + + + Y YF TV ++C G+ + S ++
Sbjct: 587 SGPAPLCKLSL-LAVQCSHVHIANGYKISGKEAPYFYNDTVT-FKCYSGFTLKGS--SQI 642
Query: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSF 203
C + W + C+K++C + +R ++P G ++ SC GY+L G
Sbjct: 643 RCKADNTWDPEIPVCEKETCQH---VRQSLQELPAGSRV-ELVNTSCQDGYQLTGHAYQM 698
Query: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACNKGFTMIGE 262
C + + + W +P C+ I+C PP I NG G +++ Y V+Y C++GF ++GE
Sbjct: 699 CQDAENGI-WFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGE 757
Query: 263 HSIYC-TVNNDEGEWSGPPPECRGKSLTSKVP 293
+ C + + G WSGP P+C ++ P
Sbjct: 758 KKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCP 789
Score = 85.9 bits (211), Expect = 7e-17
Identities = 72/273 (26%), Positives = 109/273 (39%), Gaps = 38/273 (13%)
Query: 30 PAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSD 89
P +C PP++ N Q F T I Y C +V + GE +S+ C W+
Sbjct: 404 PVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV-GE-ESIQCTSEGVWTP 461
Query: 90 IEEFCN-RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQN 148
C +CE R + ++ + V C GY+ S+ + C
Sbjct: 462 PVPQCKVAACEATGRQLLTKPQHQFVRPD-------VNSSCGEGYKLSGSVYQE--CQGT 512
Query: 149 LKWSTAVEFCKKKSCPNPGEIRNGQI------DVPGGILFGATISFSCNTG------YKL 196
+ W + CK+ +CP P I NG D P +G T++++CN G + L
Sbjct: 513 IPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFP----YGTTVTYTCNPGPERGVEFSL 568
Query: 197 FGSTSSFCLISGSSV-QWSDPLPECR----EIYCPAPPQIDNGI-IQGERDHYGYRQSVT 250
G ++ C + WS P P C+ + C + I NG I G+ Y Y +VT
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVT 627
Query: 251 YACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
+ C GFT+ G I C +N W P C
Sbjct: 628 FKCYSGFTLKGSSQIRCKADN---TWDPEIPVC 657
Score = 79.0 bits (193), Expect = 8e-15
Identities = 71/244 (29%), Positives = 104/244 (42%), Gaps = 42/244 (17%)
Query: 65 CEESF-VKIPGEKDSVICLKGSQWSDI----EEFCNRSCEVPTRLNSASLKQPYITQNYF 119
C+E + ++ P VI +G W+ + E FC P LN + +Y
Sbjct: 242 CDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSP---PPILNGRHIGNSLANVSY- 297
Query: 120 PVGTVVEYECRPGYRR--------EPSLSPKLTCLQNLKWSTAVEFCKKKS----CPNP- 166
G++V Y C P E +L + + WS C+ + CP+P
Sbjct: 298 --GSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQ 355
Query: 167 ---GEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREI 223
G + +GQ D + T+ F+C G+ L GS C G+ W P C E
Sbjct: 356 ILRGRMVSGQKD---RYTYNDTVIFACMFGFTLKGSKQIRCNAQGT---WEPSAPVC-EK 408
Query: 224 YCPAPPQIDNGIIQGERDH---YGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
C APP I NG Q E H + S+ Y+CN G+ ++GE SI CT EG W+ P
Sbjct: 409 ECQAPPNILNG--QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCT---SEGVWTPPV 463
Query: 281 PECR 284
P+C+
Sbjct: 464 PQCK 467
Score = 75.1 bits (183), Expect = 1e-13
Identities = 63/204 (30%), Positives = 89/204 (43%), Gaps = 26/204 (12%)
Query: 121 VGTVVEYECRPGYRREPSLSPKLTCLQNLK----WSTAVEFC----KKKSCPNPGEIRNG 172
VGTV+ Y C +R S L C+ K W C K SCP P I G
Sbjct: 43 VGTVIRYSCSGTFRLIGEKS--LLCITKDKVDGTWDKPAPKCEYFNKYSSCPEP--IVPG 98
Query: 173 QIDVPGGILF--GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIY---CPA 227
+ G + G +++F+C T + + G+ S +C +++ LP C ++ CPA
Sbjct: 99 GYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC--QANNMWGPTRLPTCVSVFPLECPA 156
Query: 228 PPQIDNGIIQGER-DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC--- 283
P I NG E SVTY+C G+ ++GE I C G+WS PP C
Sbjct: 157 LPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCL---SSGKWSAVPPTCEEA 213
Query: 284 RGKSLTSKVPPTVQKPTTVNVPTT 307
R KSL V++P + V T
Sbjct: 214 RCKSLGRFPNGKVKEPPILRVGVT 237
Score = 65.5 bits (158), Expect = 9e-11
Identities = 53/186 (28%), Positives = 78/186 (41%), Gaps = 23/186 (12%)
Query: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLK----WSTAVEFCKKKS----CPNPGEIR 170
F G V YEC G+ KL C + K WS C + CPNP E++
Sbjct: 738 FLYGNEVSYECDQGFYLLGE--KKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNP-EVK 794
Query: 171 NGQI--DVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECRE---IYC 225
+G + CN G+ + GS C + W +P C + I C
Sbjct: 795 HGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRCHTDNT---WVPGVPTCIKKAFIGC 851
Query: 226 PAPPQIDNGIIQGER-DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
P PP+ NG G + S+ Y+C++G+ ++GE + CT EG WS P P C+
Sbjct: 852 PPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCT---HEGTWSQPAPHCK 908
Query: 285 GKSLTS 290
+ +S
Sbjct: 909 EVNCSS 914
Score = 60.1 bits (144), Expect = 4e-09
Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 7/116 (6%)
Query: 162 SCPNPGEIRNGQIDVPGG-ILFGATISFSCNTGYKLFGSTSSFCLISGS-SVQWSDPLPE 219
SC +P I NG+I I G I +SC+ ++L G S C+ W P P+
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 220 C----REIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNN 271
C + CP P I+G Y + SVT+AC F+M G S++C NN
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTP-YRHGDSVTFACKTNFSMNGNKSVWCQANN 136
Score = 48.9 bits (115), Expect = 9e-06
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 7/136 (5%)
Query: 28 CLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQW 87
C+ + C PP PN F I Y C++ ++ + GE ++C W
Sbjct: 843 CIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV-GEA-LLLCTHEGTW 900
Query: 88 SDIEEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCL 146
S C +C P ++ +++ + + G VV EC GY E SP+ C
Sbjct: 901 SQPAPHCKEVNCSSPADMD--GIQKGLEPRKMYQYGAVVTLECEDGYMLEG--SPQSQCQ 956
Query: 147 QNLKWSTAVEFCKKKS 162
+ +W+ + C+ +S
Sbjct: 957 SDHQWNPPLAVCRSRS 972
Score = 43.5 bits (101), Expect = 4e-04
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 223 IYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYC-TVNNDEGEWSGPPP 281
I C +PP I NG I + Y+C+ F +IGE S+ C T + +G W P P
Sbjct: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80
Query: 282 ECRGKSLTSKVPPTV 296
+C + S P +
Sbjct: 81 KCEYFNKYSSCPEPI 95
Score = 32.0 bits (71), Expect = 1.1
Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 2/67 (2%)
Query: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
+C P D+ Q LE R + V+T +CE+ ++ + G S C QW+ C
Sbjct: 911 NCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM-LEGSPQSQ-CQSDHQWNPPLAVC 968
Query: 95 NRSCEVP 101
P
Sbjct: 969 RSRSLAP 975
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 119 bits (297), Expect = 7e-27
Identities = 82/263 (31%), Positives = 123/263 (46%), Gaps = 33/263 (12%)
Query: 40 PDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCE 99
P VP + G T + +T+ C+ +F + G K SV C + W
Sbjct: 94 PIVPGGYK-IRGSTPYRHGDSVTFACKTNF-SMNGNK-SVWCQANNMWGPTR-------- 142
Query: 100 VPTRLNSASLKQP---------YITQNYFPV--GTVVEYECRPGYRREPSLSPKLTCLQN 148
+PT ++ L+ P + ++N + G V Y C GY + CL +
Sbjct: 143 LPTCVSVFPLECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKI--INCLSS 200
Query: 149 LKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISG 208
KWS C++ C + G NG++ P + G T +F C+ GY+L G SS C+I+G
Sbjct: 201 GKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAG 260
Query: 209 SSVQWSDPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNK------GFTMIG 261
V W+ +P C EI+CP+PP I NG I + Y VTY C+ F +IG
Sbjct: 261 QGVAWT-KMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIG 319
Query: 262 EHSIYCTVNNDE-GEWSGPPPEC 283
E ++ CTV++ + G WSGP P C
Sbjct: 320 ESTLRCTVDSQKTGTWSGPAPRC 342
Score = 107 bits (268), Expect = 2e-23
Identities = 73/277 (26%), Positives = 123/277 (44%), Gaps = 28/277 (10%)
Query: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
+C P + N E S +TY CE ++ + GEK + CL +WS + C
Sbjct: 153 ECPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLV-GEK-IINCLSSGKWSAVPPTC 210
Query: 95 NRS-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRRE-PSLSPKLTCLQNLKWS 152
+ C+ R + +K+P I + VG + C GYR + P S + Q + W
Sbjct: 211 EEARCKSLGRFPNGKVKEPPILR----VGVTANFFCDEGYRLQGPPSSRCVIAGQGVAW- 265
Query: 153 TAVEFCKKKSCPNPGEIRNGQI--DVPGGILFGATISFSCN------TGYKLFGSTSSFC 204
T + C++ CP+P I NG+ + + +G+ ++++C+ + L G ++ C
Sbjct: 266 TKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRC 325
Query: 205 LISGSSV-QWSDPLPECR----EIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTM 259
+ WS P P C + CP P + ++ G++D Y Y +V +AC GFT+
Sbjct: 326 TVDSQKTGTWSGPAPRCELSTSAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL 385
Query: 260 IGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
G I C N +G W P C + + PP +
Sbjct: 386 KGSKQIRC---NAQGTWEPSAPVCEKE---CQAPPNI 416
Score = 98.2 bits (243), Expect = 1e-20
Identities = 67/241 (27%), Positives = 112/241 (46%), Gaps = 15/241 (6%)
Query: 55 FPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYI 114
F DTV T+KC F + G + C + W C + C+ P L+ +
Sbjct: 621 FYNDTV-TFKCYSGFT-LKGSSQ-IRCKADNTWDPEIPVCEKGCQSPPGLHHG--RHTGG 675
Query: 115 TQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQI 174
+F G V+Y C PGY + S + C+ + WS + C++ +C + +R
Sbjct: 676 NTVFFVSGMTVDYTCDPGYLLVGNKS--IHCMPSGNWSPSAPRCEE-TCQH---VRQSLQ 729
Query: 175 DVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNG 234
++P G ++ SC GY+L G C + + + W +P C+ I+C PP I NG
Sbjct: 730 ELPAGSRV-ELVNTSCQDGYQLTGHAYQMCQDAENGI-WFKKIPLCKVIHCHPPPVIVNG 787
Query: 235 IIQG-ERDHYGYRQSVTYACNKGFTMIGEHSIYC-TVNNDEGEWSGPPPECRGKSLTSKV 292
G +++ Y V+Y C++GF ++GE + C + + G WSGP P+C ++
Sbjct: 788 KHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRC 847
Query: 293 P 293
P
Sbjct: 848 P 848
Score = 92.8 bits (229), Expect = 5e-19
Identities = 79/269 (29%), Positives = 118/269 (43%), Gaps = 30/269 (11%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ----WSDIE 91
C PP + N + +F ++Y+C++ F + GEK + C S+ WS
Sbjct: 778 CHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLL-GEK-KLQCRSDSKGHGSWSGPS 835
Query: 92 EFCNRSCEVPTRLNSASLKQPYI---TQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQN 148
C RS V TR + +K Y T + + +V +C PG+ S + C +
Sbjct: 836 PQCLRSPPV-TRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV--IRCHTD 892
Query: 149 LKWSTAVEFCKKKS---CPNPGEIRNGQIDVPGGILF----GATISFSCNTGYKLFGSTS 201
W V C KK+ CP P + NG + GG + G +I +SC+ GY L G
Sbjct: 893 NTWVPGVPTCIKKAFIGCPPPPKTPNG--NHTGGNIARFSPGMSILYSCDQGYLLVGEAL 950
Query: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQG--ERDHYGYRQSVTYACNKGFTM 259
C G+ WS P P C+E+ C +P +D GI +G R Y Y VT C G+ +
Sbjct: 951 LLCTHEGT---WSQPAPHCKEVNCSSPADMD-GIQKGLEPRKMYQYGAVVTLECEDGYML 1006
Query: 260 IGEHSIYCTVNNDEGEWSGPPPECRGKSL 288
G C + +W+ P CR +SL
Sbjct: 1007 EGSPQSQC---QSDHQWNPPLAVCRSRSL 1032
Score = 85.9 bits (211), Expect = 7e-17
Identities = 72/273 (26%), Positives = 109/273 (39%), Gaps = 38/273 (13%)
Query: 30 PAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSD 89
P +C PP++ N Q F T I Y C +V + GE +S+ C W+
Sbjct: 404 PVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLV-GE-ESIQCTSEGVWTP 461
Query: 90 IEEFCN-RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQN 148
C +CE R + ++ + V C GY+ S+ + C
Sbjct: 462 PVPQCKVAACEATGRQLLTKPQHQFVRPD-------VNSSCGEGYKLSGSVYQE--CQGT 512
Query: 149 LKWSTAVEFCKKKSCPNPGEIRNGQI------DVPGGILFGATISFSCNTG------YKL 196
+ W + CK+ +CP P I NG D P +G T++++CN G + L
Sbjct: 513 IPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFP----YGTTVTYTCNPGPERGVEFSL 568
Query: 197 FGSTSSFCLISGSSV-QWSDPLPECR----EIYCPAPPQIDNGI-IQGERDHYGYRQSVT 250
G ++ C + WS P P C+ + C + I NG I G+ Y Y +VT
Sbjct: 569 IGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQC-SHVHIANGYKISGKEAPYFYNDTVT 627
Query: 251 YACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
+ C GFT+ G I C +N W P C
Sbjct: 628 FKCYSGFTLKGSSQIRCKADN---TWDPEIPVC 657
Score = 79.0 bits (193), Expect = 8e-15
Identities = 71/244 (29%), Positives = 104/244 (42%), Gaps = 42/244 (17%)
Query: 65 CEESF-VKIPGEKDSVICLKGSQWSDI----EEFCNRSCEVPTRLNSASLKQPYITQNYF 119
C+E + ++ P VI +G W+ + E FC P LN + +Y
Sbjct: 242 CDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSP---PPILNGRHIGNSLANVSY- 297
Query: 120 PVGTVVEYECRPGYRR--------EPSLSPKLTCLQNLKWSTAVEFCKKKS----CPNP- 166
G++V Y C P E +L + + WS C+ + CP+P
Sbjct: 298 --GSIVTYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHPQ 355
Query: 167 ---GEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREI 223
G + +GQ D + T+ F+C G+ L GS C G+ W P C E
Sbjct: 356 ILRGRMVSGQKD---RYTYNDTVIFACMFGFTLKGSKQIRCNAQGT---WEPSAPVC-EK 408
Query: 224 YCPAPPQIDNGIIQGERDH---YGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPP 280
C APP I NG Q E H + S+ Y+CN G+ ++GE SI CT EG W+ P
Sbjct: 409 ECQAPPNILNG--QKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCT---SEGVWTPPV 463
Query: 281 PECR 284
P+C+
Sbjct: 464 PQCK 467
Score = 75.1 bits (183), Expect = 1e-13
Identities = 63/204 (30%), Positives = 89/204 (43%), Gaps = 26/204 (12%)
Query: 121 VGTVVEYECRPGYRREPSLSPKLTCLQNLK----WSTAVEFC----KKKSCPNPGEIRNG 172
VGTV+ Y C +R S L C+ K W C K SCP P I G
Sbjct: 43 VGTVIRYSCSGTFRLIGEKS--LLCITKDKVDGTWDKPAPKCEYFNKYSSCPEP--IVPG 98
Query: 173 QIDVPGGILF--GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIY---CPA 227
+ G + G +++F+C T + + G+ S +C +++ LP C ++ CPA
Sbjct: 99 GYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC--QANNMWGPTRLPTCVSVFPLECPA 156
Query: 228 PPQIDNGIIQGER-DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC--- 283
P I NG E SVTY+C G+ ++GE I C G+WS PP C
Sbjct: 157 LPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCL---SSGKWSAVPPTCEEA 213
Query: 284 RGKSLTSKVPPTVQKPTTVNVPTT 307
R KSL V++P + V T
Sbjct: 214 RCKSLGRFPNGKVKEPPILRVGVT 237
Score = 66.2 bits (160), Expect = 5e-11
Identities = 72/336 (21%), Positives = 120/336 (35%), Gaps = 90/336 (26%)
Query: 29 LPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS 88
+P C PP + + + F + Y C+ ++ + G K S+ C+ WS
Sbjct: 654 IPVCEKGCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLV-GNK-SIHCMPSGNWS 711
Query: 89 DIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEY---ECRPGYRREPSLSPKLTC 145
C +C+ + SL++ P G+ VE C+ GY+
Sbjct: 712 PSAPRCEETCQHVRQ----SLQE-------LPAGSRVELVNTSCQDGYQLTGHAYQMCQD 760
Query: 146 LQNLKWSTAVEFCKKKSCPNPGEIRNGQID--VPGGILFGATISFSCNT----------- 192
+N W + CK C P I NG+ + L+G +S+ C+
Sbjct: 761 AENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQ 820
Query: 193 ----------------------------------GYKLFGSTSSFC-------------L 205
GYKL + S++ +
Sbjct: 821 CRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYVDCNPGFI 880
Query: 206 ISGSSV-------QWSDPLPECRE---IYCPAPPQIDNGIIQGER-DHYGYRQSVTYACN 254
++GS V W +P C + I CP PP+ NG G + S+ Y+C+
Sbjct: 881 MNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCD 940
Query: 255 KGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTS 290
+G+ ++GE + CT EG WS P P C+ + +S
Sbjct: 941 QGYLLVGEALLLCT---HEGTWSQPAPHCKEVNCSS 973
Score = 63.9 bits (154), Expect = 3e-10
Identities = 68/275 (24%), Positives = 107/275 (38%), Gaps = 31/275 (11%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCE---ESFVKIPGEKDSVI-CLKGSQ----W 87
C PP + N FP T +TY C E V+ +S I C Q W
Sbjct: 527 CPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGESTIRCTSNDQERGTW 586
Query: 88 SDIEEFCNRSCEVPTRLNSASLKQPYITQN----YFPVGTVVEYECRPGYRREPSLSPKL 143
S C S + + + + Y YF TV ++C G+ + S ++
Sbjct: 587 SGPAPLCKLSL-LAVQCSHVHIANGYKISGKEAPYFYNDTVT-FKCYSGFTLKGS--SQI 642
Query: 144 TCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF--GATISFSCNTGYKLFGSTS 201
C + W + C+K C +P + +G+ + F G T+ ++C+ GY L G+ S
Sbjct: 643 RCKADNTWDPEIPVCEK-GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKS 701
Query: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIG 261
C+ SG+ WS P C E C Q + G R + V +C G+ + G
Sbjct: 702 IHCMPSGN---WSPSAPRCEET-CQHVRQSLQELPAGSR-----VELVNTSCQDGYQLTG 752
Query: 262 EHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
H+ + + G W P C K + PP +
Sbjct: 753 -HAYQMCQDAENGIWFKKIPLC--KVIHCHPPPVI 784
Score = 60.1 bits (144), Expect = 4e-09
Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 7/116 (6%)
Query: 162 SCPNPGEIRNGQIDVPGG-ILFGATISFSCNTGYKLFGSTSSFCLISGS-SVQWSDPLPE 219
SC +P I NG+I I G I +SC+ ++L G S C+ W P P+
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 220 C----REIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNN 271
C + CP P I+G Y + SVT+AC F+M G S++C NN
Sbjct: 82 CEYFNKYSSCPEPIVPGGYKIRGSTP-YRHGDSVTFACKTNFSMNGNKSVWCQANN 136
Score = 48.9 bits (115), Expect = 9e-06
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 7/136 (5%)
Query: 28 CLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQW 87
C+ + C PP PN F I Y C++ ++ + GE ++C W
Sbjct: 902 CIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLV-GEA-LLLCTHEGTW 959
Query: 88 SDIEEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCL 146
S C +C P ++ +++ + + G VV EC GY E SP+ C
Sbjct: 960 SQPAPHCKEVNCSSPADMD--GIQKGLEPRKMYQYGAVVTLECEDGYMLEG--SPQSQCQ 1015
Query: 147 QNLKWSTAVEFCKKKS 162
+ +W+ + C+ +S
Sbjct: 1016 SDHQWNPPLAVCRSRS 1031
Score = 43.5 bits (101), Expect = 4e-04
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 223 IYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYC-TVNNDEGEWSGPPP 281
I C +PP I NG I + Y+C+ F +IGE S+ C T + +G W P P
Sbjct: 21 ISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAP 80
Query: 282 ECRGKSLTSKVPPTV 296
+C + S P +
Sbjct: 81 KCEYFNKYSSCPEPI 95
Score = 32.0 bits (71), Expect = 1.1
Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 2/67 (2%)
Query: 35 DCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC 94
+C P D+ Q LE R + V+T +CE+ ++ + G S C QW+ C
Sbjct: 970 NCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYM-LEGSPQSQ-CQSDHQWNPPLAVC 1027
Query: 95 NRSCEVP 101
P
Sbjct: 1028 RSRSLAP 1034
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 116 bits (291), Expect = 4e-26
Identities = 81/279 (29%), Positives = 127/279 (45%), Gaps = 33/279 (11%)
Query: 28 CLPAVWGD---------CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDS 78
C+P GD C P + N + E T E +T+ C+E + + K
Sbjct: 1772 CVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAE---VTFSCQEGYQLMGVTK-- 1826
Query: 79 VICLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREP 137
+ CL+ +W+ + +C SC P A + I + F G+ V Y C GY
Sbjct: 1827 ITCLESGEWNHLIPYCKAVSCGKP-----AIPENGCIEELAFTFGSKVTYRCNKGYTLAG 1881
Query: 138 SLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLF 197
+ +CL N WS + C+ C +P I NG+ + G+ + +T S+SC+TGY L
Sbjct: 1882 D--KESSCLANSSWSHSPPVCEPVKCSSPENINNGKY-ILSGLTYLSTASYSCDTGYSLQ 1938
Query: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGF 257
G + C SG W P C ++C PP I + +I G +++ +R +VTY C +G+
Sbjct: 1939 GPSIIECTASGI---WDRAPPACHLVFCGEPPAIKDAVITG--NNFTFRNTVTYTCKEGY 1993
Query: 258 TMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
T+ G +I C +G+WS +C S PP V
Sbjct: 1994 TLAGLDTIECLA---DGKWSRSDQQCLAVSCDE--PPIV 2027
Score = 110 bits (275), Expect = 3e-24
Identities = 76/277 (27%), Positives = 123/277 (44%), Gaps = 20/277 (7%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
C PP V + + F +V+++KC E FV K + C++G QW+ +
Sbjct: 2083 CEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAK--IECMRGGQWNPSP--MS 2138
Query: 96 RSCEVPTRLNSA-SLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
C +P R S+ Y + + + G +V Y C G+ + K TC +WS+
Sbjct: 2139 IQC-IPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGE--KKSTCEATGQWSSP 2195
Query: 155 VEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C SC P ++ NG ++ G +F + + + CN GYK GS C ++ W
Sbjct: 2196 IPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVC---QANRHWH 2252
Query: 215 DPLP-ECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDE 273
P C + C PP I NG ++GE G V + CN+G+ ++G+ S C
Sbjct: 2253 SESPLMCVPLDCGKPPPIQNGFMKGENFEVG--SKVQFFCNEGYELVGDSSWTC---QKS 2307
Query: 274 GEWSGPP-PECRGKSLTSKVPPTVQKPTTVNVPTTEV 309
G+W+ P+C PP ++ + TTEV
Sbjct: 2308 GKWNKKSNPKCMPAKCPE--PPLLENQLVLKELTTEV 2342
Score = 110 bits (275), Expect = 3e-24
Identities = 79/263 (30%), Positives = 128/263 (48%), Gaps = 29/263 (11%)
Query: 26 LLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGS 85
L+C+P DCG PP + N ++G +F + + + C E + ++ G+ S C K
Sbjct: 2257 LMCVPL---DCGKPPPIQNG--FMKGE-NFEVGSKVQFFCNEGY-ELVGDS-SWTCQKSG 2308
Query: 86 QWSDIE--EFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRRE-PSLSPK 142
+W+ + C P L + + + T+ VG VV + C+ G+ + PS+
Sbjct: 2309 KWNKKSNPKCMPAKCPEPPLLENQLVLKELTTE----VG-VVTFSCKEGHVLQGPSV--- 2360
Query: 143 LTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTS 201
L CL + +W+ + CK C P I G + +P L FG+T+ +SC G+ L G+++
Sbjct: 2361 LKCLPSQQWNDSFPVCKIVLCTPPPLISFG-VPIPSSALHFGSTVKYSCVGGFFLRGNST 2419
Query: 202 SFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIG 261
+ C G+ WS PLPEC + CP P +I NGII + Y + Y C GF ++G
Sbjct: 2420 TLCQPDGT---WSSPLPECVPVECPQPEEIPNGII--DVQGLAYLSTALYTCKPGFELVG 2474
Query: 262 EHSIYCTVNNDEGEWSGPPPECR 284
+ C + G W G P C+
Sbjct: 2475 NTTTLC---GENGHWLGGKPTCK 2494
Score = 108 bits (270), Expect = 1e-23
Identities = 67/232 (28%), Positives = 109/232 (46%), Gaps = 19/232 (8%)
Query: 53 TSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFC-NRSCEVPTRLNSASLKQ 111
++F T+++Y C + + +IC + W+ C + C++PT + L+
Sbjct: 2673 SNFLYGTMVSYTCNPGYELLGNPV--LICQEDGTWNGSAPSCISIECDLPTAPENGFLR- 2729
Query: 112 PYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRN 171
T+ +G+ V+Y C+PG+ S CL+N KWS A C+ SC P + N
Sbjct: 2730 --FTET--SMGSAVQYSCKPGHILAGS--DLRLCLENRKWSGASPRCEAISCKKPNPVMN 2783
Query: 172 GQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQI 231
G I + +T+ + C+ GY L G+ C W + P C + C +PP
Sbjct: 2784 GSIK-GSNYTYLSTLYYECDPGYVLNGTERRTC---QDDKNWDEDEPICIPVDCSSPPVS 2839
Query: 232 DNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
NG ++G D Y +++ + Y CN+GF + G S C N G WSG P+C
Sbjct: 2840 ANGQVRG--DEYTFQKEIEYTCNEGFLLEGARSRVCLAN---GSWSGATPDC 2886
Score = 107 bits (266), Expect = 3e-23
Identities = 73/254 (28%), Positives = 113/254 (44%), Gaps = 28/254 (11%)
Query: 35 DCGLPPDVPNAQPALEGRTSFPEDTV---ITYKCEESFVKIPGEKDSVICLKGSQWSDIE 91
+C LP N G F E ++ + Y C+ + D +CL+ +WS
Sbjct: 2716 ECDLPTAPEN------GFLRFTETSMGSAVQYSCKPGHIL--AGSDLRLCLENRKWSGAS 2767
Query: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
C SC+ P + + S+K NY + T+ YEC PGY + + TC +
Sbjct: 2768 PRCEAISCKKPNPVMNGSIKG----SNYTYLSTLY-YECDPGYVLNGT--ERRTCQDDKN 2820
Query: 151 WSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSS 210
W C C +P NGQ+ F I ++CN G+ L G+ S CL +GS
Sbjct: 2821 WDEDEPICIPVDCSSPPVSANGQVR-GDEYTFQKEIEYTCNEGFLLEGARSRVCLANGS- 2878
Query: 211 VQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVN 270
WS P+C + C PPQ+ NG+ +G YG+ + VT+ C++G+ + G + C
Sbjct: 2879 --WSGATPDCVPVRCATPPQLANGVTEGL--DYGFMKEVTFHCHEGYILHGAPKLTC--- 2931
Query: 271 NDEGEWSGPPPECR 284
+G W P C+
Sbjct: 2932 QSDGNWDAEIPLCK 2945
Score = 100 bits (248), Expect = 3e-21
Identities = 68/248 (27%), Positives = 111/248 (44%), Gaps = 17/248 (6%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
C LP ++ + L F + ++ C E + G SV L G+ W F +
Sbjct: 3181 CPLPENITHI---LVHGDDFSVNRQVSVSCAEGYT-FEGVNISVCQLDGT-WEP--PFSD 3233
Query: 96 RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAV 155
SC + S + ++ + + + + Y+C PGY E + + C +N +WS V
Sbjct: 3234 ESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNR--ERVCQENRQWSGGV 3291
Query: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
CK+ C P E NG+ D+ G + +SCN GY L G + + C +G+ WS
Sbjct: 3292 AICKETRCETPLEFLNGKADIENRTT-GPNVVYSCNRGYSLEGPSEAHCTENGT---WSH 3347
Query: 216 PLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGE 275
P+P C+ CP P I + E++ Y Q+V+ C +GF + G I C N +
Sbjct: 3348 PVPLCKPNPCPVPFVIPENALLSEKEFY-VDQNVSIKCREGFLLQGHGIITC---NPDET 3403
Query: 276 WSGPPPEC 283
W+ +C
Sbjct: 3404 WTQTSAKC 3411
Score = 99.8 bits (247), Expect = 4e-21
Identities = 81/267 (30%), Positives = 113/267 (42%), Gaps = 30/267 (11%)
Query: 27 LCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ 86
+C+P DC PP N Q + T E I Y C E F+ + G + S +CL
Sbjct: 2827 ICIPV---DCSSPPVSANGQVRGDEYTFQKE---IEYTCNEGFL-LEGAR-SRVCLANGS 2878
Query: 87 WSDIEEFCNRSCEVPTRLNSASLKQPYITQNY-FPVGTVVEYECRPGYRREPSLSPKLTC 145
WS C VP R + +T+ + V + C GY + PKLTC
Sbjct: 2879 WSGATPDC-----VPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGA--PKLTC 2931
Query: 146 LQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILF--GATISFSCNTGYKLFGSTSSF 203
+ W + CK +C P ++ +G P G F G I + C GYKL G++S
Sbjct: 2932 QSDGNWDAEIPLCKPVNCGPPEDLAHG---FPNGFSFIHGGHIQYQCFPGYKLHGNSSRR 2988
Query: 204 CLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEH 263
CL +GS WS P C C + P I+ G + G G ++ C KGF ++G
Sbjct: 2989 CLSNGS---WSGSSPSCLPCRC-STPVIEYGTVNGTDFDCG--KAARIQCFKGFKLLGLS 3042
Query: 264 SIYCTVNNDEGEWSGPPPECRGKSLTS 290
I C +G+WS P C S S
Sbjct: 3043 EITCEA---DGQWSSGFPHCEHTSCGS 3066
Score = 93.6 bits (231), Expect = 3e-19
Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 30/269 (11%)
Query: 25 VLLCLPAV-WGD---------CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPG 74
VL CLP+ W D C PP + P F + + Y C F + G
Sbjct: 2360 VLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHF--GSTVKYSCVGGFF-LRG 2416
Query: 75 EKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYR 134
++ G+ S + E C P + + + Q + T + Y C+PG+
Sbjct: 2417 NSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIID----VQGLAYLSTAL-YTCKPGFE 2471
Query: 135 REPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGY 194
+ + C +N W CK C P EI NG+ + +G T+++SCN G+
Sbjct: 2472 LVGNTTT--LCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTD-LHYGQTVTYSCNRGF 2528
Query: 195 KLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACN 254
+L G ++ CL +G W P C I+C +P I+NG ++G Y Y + Y+C
Sbjct: 2529 RLEGPSALTCLETGD---WDVDAPSCNAIHCDSPQPIENGFVEGA--DYSYGAIIIYSCF 2583
Query: 255 KGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
GF + G C +E WS P C
Sbjct: 2584 PGFQVAGHAMQTC----EESGWSSSIPTC 2608
Score = 87.4 bits (215), Expect = 2e-17
Identities = 74/302 (24%), Positives = 111/302 (36%), Gaps = 70/302 (23%)
Query: 28 CLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQW 87
C+P +C P ++PN ++G + Y C+ F + + +C + W
Sbjct: 2435 CVPV---ECPQPEEIPNGIIDVQGLAYL---STALYTCKPGFELVGNT--TTLCGENGHW 2486
Query: 88 SDIEEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRRE-PSLSPKLTC 145
+ C C P + + K Y +Y G V Y C G+R E PS LTC
Sbjct: 2487 LGGKPTCKAIECLKPKEILNG--KFSYTDLHY---GQTVTYSCNRGFRLEGPSA---LTC 2538
Query: 146 LQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCL 205
L+ W C C +P I NG ++ +GA I +SC G+++ G C
Sbjct: 2539 LETGDWDVDAPSCNAIHCDSPQPIENGFVE-GADYSYGAIIIYSCFPGFQVAGHAMQTCE 2597
Query: 206 ISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQS----------------- 248
SG WS +P C I C PP ID G +D GY +
Sbjct: 2598 ESG----WSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYH 2653
Query: 249 ---------------------------VTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPP 281
V+Y CN G+ ++G + C ++G W+G P
Sbjct: 2654 LGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLIC---QEDGTWNGSAP 2710
Query: 282 EC 283
C
Sbjct: 2711 SC 2712
Score = 87.0 bits (214), Expect = 3e-17
Identities = 68/247 (27%), Positives = 99/247 (40%), Gaps = 23/247 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
CG P+ P + + +F ++ I Y+CE + ++ G ++ V C + QWS C
Sbjct: 3241 CG-KPESPEHGFVVGSKYTF--ESTIIYQCEPGY-ELEGNRERV-CQENRQWSGGVAICK 3295
Query: 96 RS-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRRE-PSLSPKLTCLQNLKWST 153
+ CE P + T G V Y C GY E PS + C +N WS
Sbjct: 3296 ETRCETPLEFLNGKADIENRT-----TGPNVVYSCNRGYSLEGPS---EAHCTENGTWSH 3347
Query: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQW 213
V CK CP P I + +S C G+ L G C W
Sbjct: 3348 PVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITC---NPDETW 3404
Query: 214 SDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDE 273
+ +C +I C P ++N I +G HY Y +TY+C G+ + G C N
Sbjct: 3405 TQTSAKCEKISCGPPAHVENAIARGV--HYQYGDMITYSCYSGYMLEGFLRSVCLEN--- 3459
Query: 274 GEWSGPP 280
G W+ PP
Sbjct: 3460 GTWTSPP 3466
Score = 86.7 bits (213), Expect = 4e-17
Identities = 69/247 (27%), Positives = 97/247 (39%), Gaps = 62/247 (25%)
Query: 81 CLKGSQWSDIEEFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSL 139
CL QW+ C R SC VP L + + + + F G+ V Y+C GY
Sbjct: 1672 CLNQGQWTQPLPHCERISCGVPPPLENG-----FHSADDFYAGSTVTYQCNNGYYLLG-- 1724
Query: 140 SPKLTCLQNLKWSTAVEFC-------------KKKSCPN--------------------- 165
++ C N W+ C + SC N
Sbjct: 1725 DSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCA 1784
Query: 166 -------PGEIRNGQIDVPGGILF--GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDP 216
PG NG G ++ GA ++FSC GY+L G T CL SG +W+
Sbjct: 1785 EPIKCKAPGNPENGH---SSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESG---EWNHL 1838
Query: 217 LPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEW 276
+P C+ + C P +NG I E + + VTY CNKG+T+ G+ C N+ W
Sbjct: 1839 IPYCKAVSCGKPAIPENGCI--EELAFTFGSKVTYRCNKGYTLAGDKESSCLANS---SW 1893
Query: 277 SGPPPEC 283
S PP C
Sbjct: 1894 SHSPPVC 1900
Score = 84.3 bits (207), Expect = 2e-16
Identities = 70/253 (27%), Positives = 102/253 (40%), Gaps = 25/253 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
CG P +PNA TS ++ VITY C +V I G D +IC + WS C
Sbjct: 3064 CGSLPMIPNA---FISETSSWKENVITYSCRSGYV-IQGSSD-LICTEKGVWSQPYPVCE 3118
Query: 96 R-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTA 154
SC P + +A T + V+ C GY + + TC ++ +W
Sbjct: 3119 PLSCGSPPSVANA-----VATGEAHTYESEVKLRCLEGYTMDTD-TDTFTCQKDGRWFPE 3172
Query: 155 VEFCKKKSCPNPGEIRNGQIDVPG-GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQW 213
C K CP P I + I V G +S SC GY G S C + G+ W
Sbjct: 3173 RISCSPKKCPLPENITH--ILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGT---W 3227
Query: 214 SDPLPE--CREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNN 271
P + C + C P ++G + G + Y + ++ Y C G+ + G C N
Sbjct: 3228 EPPFSDESCSPVSCGKPESPEHGFVVGSK--YTFESTIIYQCEPGYELEGNRERVCQENR 3285
Query: 272 DEGEWSGPPPECR 284
+WSG C+
Sbjct: 3286 ---QWSGGVAICK 3295
Score = 82.8 bits (203), Expect = 6e-16
Identities = 36/101 (35%), Positives = 57/101 (56%), Gaps = 8/101 (7%)
Query: 183 GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDH 242
G+ ++ C+ G++L G+ +CL G QW+ PLP C I C PP ++NG + +
Sbjct: 1651 GSKVNLFCDPGFQLVGNPVQYCLNQG---QWTQPLPHCERISCGVPPPLENGFHSADDFY 1707
Query: 243 YGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
G +VTY CN G+ ++G+ ++CT D G W+G P C
Sbjct: 1708 AG--STVTYQCNNGYYLLGDSRMFCT---DNGSWNGVSPSC 1743
Score = 82.4 bits (202), Expect = 7e-16
Identities = 69/260 (26%), Positives = 106/260 (40%), Gaps = 23/260 (8%)
Query: 27 LCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ 86
LC P +CG P D+ + P SF I Y+C + K+ G S CL
Sbjct: 2943 LCKPV---NCGPPEDLAHGFP---NGFSFIHGGHIQYQCFPGY-KLHGNS-SRRCLSNGS 2994
Query: 87 WSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCL 146
WS C +P R ++ ++ + F G +C G++ LS ++TC
Sbjct: 2995 WSGSSPSC-----LPCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLL-GLS-EITCE 3047
Query: 147 QNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLI 206
+ +WS+ C+ SC + I N I I++SC +GY + GS+ C
Sbjct: 3048 ADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENV-ITYSCRSGYVIQGSSDLICTE 3106
Query: 207 SGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIY 266
G WS P P C + C +PP + N + GE + Y V C +G+TM + +
Sbjct: 3107 KGV---WSQPYPVCEPLSCGSPPSVANAVATGEA--HTYESEVKLRCLEGYTMDTDTDTF 3161
Query: 267 CTVNNDEGEWSGPPPECRGK 286
+G W C K
Sbjct: 3162 TC--QKDGRWFPERISCSPK 3179
Score = 80.5 bits (197), Expect = 3e-15
Identities = 51/174 (29%), Positives = 76/174 (43%), Gaps = 11/174 (6%)
Query: 110 KQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEI 169
+ P + F GT+V Y C PGY E +P L C ++ W+ + C C P
Sbjct: 2666 ESPATHSSNFLYGTMVSYTCNPGY--ELLGNPVLICQEDGTWNGSAPSCISIECDLPTAP 2723
Query: 170 RNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPP 229
NG + + G+ + +SC G+ L GS CL + +WS P C I C P
Sbjct: 2724 ENGFLRFTETSM-GSAVQYSCKPGHILAGSDLRLCL---ENRKWSGASPRCEAISCKKPN 2779
Query: 230 QIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
+ NG I+G +Y Y ++ Y C+ G+ + G C D+ W P C
Sbjct: 2780 PVMNGSIKG--SNYTYLSTLYYECDPGYVLNGTERRTC---QDDKNWDEDEPIC 2828
Score = 70.9 bits (172), Expect = 2e-12
Identities = 62/268 (23%), Positives = 104/268 (38%), Gaps = 27/268 (10%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVI-CLKGSQWSDIEEFC 94
C P ++ N + L G T + +Y C+ + + S+I C W C
Sbjct: 1905 CSSPENINNGKYILSGLTYL---STASYSCDTGYSL---QGPSIIECTASGIWDRAPPAC 1958
Query: 95 NRS-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
+ C P ++K IT N F V Y C+ GY + CL + KWS
Sbjct: 1959 HLVFCGEPP-----AIKDAVITGNNFTFRNTVTYTCKEGYTLAGL--DTIECLADGKWSR 2011
Query: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQW 213
+ + C SC P + + + LFG + C+ GY L ++ C G +W
Sbjct: 2012 SDQQCLAVSCDEPPIVDHASPETAHR-LFGDIAFYYCSDGYSLADNSQLLCNAQG---KW 2067
Query: 214 SDP----LPECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACNKGFTMIGEHSIYCT 268
P +P C +C PP + I++ + + V++ C +GF + I C
Sbjct: 2068 VPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECM 2127
Query: 269 VNNDEGEWSGPPPECRGKSLTSKVPPTV 296
G+W+ P + + PP++
Sbjct: 2128 RG---GQWNPSPMSIQCIPVRCGEPPSI 2152
Score = 68.9 bits (167), Expect = 8e-12
Identities = 68/291 (23%), Positives = 105/291 (36%), Gaps = 63/291 (21%)
Query: 122 GTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGIL 181
G+ V C PG++ + P CL +W+ + C++ SC P + NG
Sbjct: 1651 GSKVNLFCDPGFQLVGN--PVQYCLNQGQWTQPLPHCERISCGVPPPLENG-FHSADDFY 1707
Query: 182 FGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECRE------------------- 222
G+T+++ CN GY L G + FC +GS W+ P C +
Sbjct: 1708 AGSTVTYQCNNGYYLLGDSRMFCTDNGS---WNGVSPSCLDVDECAVGSDCSEHASCLNV 1764
Query: 223 ----------------------IYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMI 260
I C AP +NG GE Y VT++C +G+ ++
Sbjct: 1765 DGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGE--IYTVGAEVTFSCQEGYQLM 1822
Query: 261 GEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKT 320
G I C + GEW+ P C K+++ P + + T S + +
Sbjct: 1823 GVTKITCL---ESGEWNHLIPYC--KAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGY 1877
Query: 321 T---------TPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGS 362
T N+ + S PV K N G SG T L + S
Sbjct: 1878 TLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTAS 1928
Score = 55.1 bits (131), Expect = 1e-07
Identities = 41/147 (27%), Positives = 61/147 (41%), Gaps = 8/147 (5%)
Query: 138 SLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKL 196
S SP+ C+ + + + C+ CP NG I F A C+ G+ L
Sbjct: 354 STSPE-DCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDL 412
Query: 197 FGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKG 256
GS+ CL +G WS CR CP Q +G I Y+ + AC++G
Sbjct: 413 VGSSIILCLPNGL---WSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEG 469
Query: 257 FTMIGEHSIYCTVNNDEGEWSGPPPEC 283
+ + G + C N+ +W GP P C
Sbjct: 470 YRLEGSDKLTCQGNS---QWDGPEPRC 493
Score = 34.7 bits (78), Expect = 0.18
Identities = 41/162 (25%), Positives = 60/162 (37%), Gaps = 28/162 (17%)
Query: 79 VICLKGSQWSDIEEFCN-RSCEVPTRLNSASLKQPY-----ITQNYFPVGTVVEYECRPG 132
++CL WS E +C R+C L+QP + T C G
Sbjct: 418 ILCLPNGLWSGSESYCRVRTCP--------HLRQPKHGHISCSTREMLYKTTCLVACDEG 469
Query: 133 YRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGG-----ILFGATIS 187
YR E S KLTC N +W C ++ C + ++ I P FG
Sbjct: 470 YRLEGS--DKLTCQGNSQWDGPEPRCVERHC-STFQMPKDVIISPHNCGKQPAKFGTICY 526
Query: 188 FSCNTGYKLFGSTSSF-CLISGSSVQWSDPLPE--CREIYCP 226
SC G+ L G C SG +W+ + C+++ P
Sbjct: 527 VSCRQGFILSGVKEMLRCTTSG---KWNVGVQAAVCKDVEAP 565
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 108 bits (269), Expect = 1e-23
Identities = 81/256 (31%), Positives = 111/256 (43%), Gaps = 24/256 (9%)
Query: 34 GDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
G CG+P + N Q + G DTV+ Y+C F I IC + WS
Sbjct: 2775 GHCGIPELIVNGQ--VIGENYGYRDTVV-YQCNPGFRLIGSSVR--ICQQDHNWSGQLPS 2829
Query: 94 CNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWS 152
C SC P S + N F VV + C GY + K C N +WS
Sbjct: 2830 CVPVSCGHP-----GSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPT--KAQCQANRQWS 2882
Query: 153 TAVEFCKKKSCPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
CK +C +PG N + + G +G + + CN GY LFGS+ C +G
Sbjct: 2883 HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNG- 2941
Query: 210 SVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTV 269
QW PLPEC I C P N ++ GE+ Y + +V Y+C +++G+ S C +
Sbjct: 2942 --QWDKPLPECIMIDCGHPGVPPNAVLSGEK--YTFGSTVHYSCTGKRSLLGQSSRTCQL 2997
Query: 270 NNDEGEWSGPPPECRG 285
N G WSG P C G
Sbjct: 2998 N---GHWSGSQPHCSG 3010
Score = 105 bits (261), Expect = 1e-22
Identities = 87/288 (30%), Positives = 120/288 (41%), Gaps = 38/288 (13%)
Query: 25 VLLCLP----------AVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPG 74
VL+C P + DCG P PNA L G + + + Y C +
Sbjct: 2934 VLICQPNGQWDKPLPECIMIDCGHPGVPPNA--VLSGE-KYTFGSTVHYSCTGKRSLLG- 2989
Query: 75 EKDSVICLKGSQWSDIEEFCNR----SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECR 130
+ S C WS + C+ +C P S ++ + F + V Y C
Sbjct: 2990 -QSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQE-----SNFRTKSTVRYACD 3043
Query: 131 PGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSC 190
GY S + TCL N W+ CK C NPG NG++ G F +++ +SC
Sbjct: 3044 TGYILHGS--EERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSC 3101
Query: 191 NTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVT 250
GY L G + C +G+ WS LP C I C P NG+ G D Y Q+V+
Sbjct: 3102 MEGYILSGPSVRQCTANGT---WSGTLPNCTIISCGDPGIPANGLRYG--DDYVVGQNVS 3156
Query: 251 YACNKGFTM--IGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Y C G+TM G CT+N G WSG P CR ++T PP +
Sbjct: 3157 YMCQPGYTMELNGSRIRTCTIN---GTWSGVMPTCR--AVTCPTPPQI 3199
Score = 98.2 bits (243), Expect = 1e-20
Identities = 78/256 (30%), Positives = 110/256 (42%), Gaps = 25/256 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
CG+P N T + T +TY C + + E + +C WS+ +
Sbjct: 2592 CGIPKAPTNGGILT---TDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK--T 2646
Query: 96 RSCEVPT--RLNSASLKQP---YITQNYFPVGTVVEYECRPGYRREPSLSP-KLTCLQNL 149
C V T +NS L+ + +++ T V + C PGY L P + CL N
Sbjct: 2647 PRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYH---GLGPASIECLPNG 2703
Query: 150 KWSTAVE--FCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLIS 207
WS E +C+ SC NG + +G+T F+C+ G+ L GS CL S
Sbjct: 2704 TWSWRNERPYCQIISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS 2762
Query: 208 GSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYC 267
G WS+ C +C P I NG + GE +YGYR +V Y CN GF +IG C
Sbjct: 2763 GL---WSESETRCLAGHCGIPELIVNGQVIGE--NYGYRDTVVYQCNPGFRLIGSSVRIC 2817
Query: 268 TVNNDEGEWSGPPPEC 283
+ WSG P C
Sbjct: 2818 ---QQDHNWSGQLPSC 2830
Score = 97.4 bits (241), Expect = 2e-20
Identities = 79/274 (28%), Positives = 120/274 (43%), Gaps = 29/274 (10%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKI-PGEKDSVICLKGSQWSDIEEFC 94
CG P N + T+F + Y C E ++ P + C WS C
Sbjct: 3074 CGNPGTTANGKVFRIDGTTFSSSVI--YSCMEGYILSGPSVRQ---CTANGTWSGTLPNC 3128
Query: 95 NR-SCEVP-TRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWS 152
SC P N Y+ VG V Y C+PGY E + S TC N WS
Sbjct: 3129 TIISCGDPGIPANGLRYGDDYV------VGQNVSYMCQPGYTMELNGSRIRTCTINGTWS 3182
Query: 153 TAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
+ C+ +CP P +I NG+++ +G +IS+ C+ GY+L C+ +G+
Sbjct: 3183 GVMPTCRAVTCPTPPQISNGRLE-GTNFDWGFSISYICSPGYELSFPAVLTCVGNGT--- 3238
Query: 213 WSDPLPECREIYCPAPPQIDNGI-IQGERD--HYGYRQSVTYACNKGFTMIGEHSIYCTV 269
WS +P+C +C P GI QG+R+ + Y+ V+++CN F ++G + C
Sbjct: 3239 WSGEVPQCLPKFCGDP-----GIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQA 3293
Query: 270 NNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVN 303
+G WSG P C + TS P V + + N
Sbjct: 3294 ---DGTWSGSSPHCIEPTQTSCENPGVPRHGSQN 3324
Score = 67.0 bits (162), Expect = 3e-11
Identities = 59/212 (27%), Positives = 89/212 (41%), Gaps = 33/212 (15%)
Query: 16 GELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGE 75
GE+P+ CLP GD G+P AQ EG+ SF + +++ C F+ +
Sbjct: 3241 GEVPQ-------CLPKFCGDPGIP-----AQGKREGK-SFIYQSEVSFSCNFPFILVGSS 3287
Query: 76 KDSVICLKGSQWSDIEEFC----NRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRP 131
+ IC WS C SCE P S + F VG+VV++ C+
Sbjct: 3288 --TRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF----GFQVGSVVQFHCKK 3341
Query: 132 GYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQI---DVPGGILFGATISF 188
G+ + S + TCL +L WS C SC P + + D+P G T+ +
Sbjct: 3342 GHLLQGSTTR--TCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPS---HGYTLIY 3396
Query: 189 SCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
+C G+ L G T + S W+ +P C
Sbjct: 3397 TCQPGFFLAGGTEH--RVCRSDNTWTGKVPIC 3426
Score = 65.1 bits (157), Expect = 1e-10
Identities = 73/275 (26%), Positives = 112/275 (40%), Gaps = 32/275 (11%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESF-VKIPGEKDSVICLKGSQWS-DIEEF 93
C PP + N + LEG T+F I+Y C + + P + C+ WS ++ +
Sbjct: 3193 CPTPPQISNGR--LEG-TNFDWGFSISYICSPGYELSFPAV---LTCVGNGTWSGEVPQC 3246
Query: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
+ C P Q F + V + C + S + C + WS
Sbjct: 3247 LPKFCGDP-----GIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTR--ICQADGTWSG 3299
Query: 154 AVEFC---KKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSS 210
+ C + SC NPG R+G + G G+ + F C G+ L GST+ CL
Sbjct: 3300 SSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL---PD 3356
Query: 211 VQWSDPLPECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACNKGFTMIG--EHSIYC 267
+ WS PEC C P + + G + +GY ++ Y C GF + G EH + C
Sbjct: 3357 LTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGY--TLIYTCQPGFFLAGGTEHRV-C 3413
Query: 268 TVNNDEGEWSGPPPECR-GKSLTSKVP-PTVQKPT 300
+N W+G P C G + K P P + P+
Sbjct: 3414 RSDN---TWTGKVPICEAGSKILVKDPRPALGTPS 3445
Score = 53.1 bits (126), Expect = 5e-07
Identities = 34/85 (40%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 161 KSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
+SCP+P RNG + + G TISF C GY L G+++ CL G S W+ PLP C
Sbjct: 2182 QSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALTCL-HGVSRNWNHPLPRC 2239
Query: 221 REIYCPAPPQIDNGII--QGERDHY 243
E C NG I G D Y
Sbjct: 2240 -EALCGGNITAMNGTIYSPGYPDEY 2263
Score = 52.8 bits (125), Expect = 6e-07
Identities = 36/124 (29%), Positives = 52/124 (41%), Gaps = 6/124 (4%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQ-WSDPLPECR 221
C P +G I G + + ++C+ G++L G +S+ C S W P+P C+
Sbjct: 2529 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2588
Query: 222 EIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWS--GP 279
I C P NG I G R VTY CN G+ + + V +G WS
Sbjct: 2589 AISCGIPKAPTNGGILTTDYLVGTR--VTYFCNDGY-RLSSKELTTAVCQSDGTWSNHNK 2645
Query: 280 PPEC 283
P C
Sbjct: 2646 TPRC 2649
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 5/75 (6%)
Query: 163 CPNPGEIRNG-QIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECR 221
C +PG + G +I GI G T++FSC++GY+L G++ CL G V WS PLP C
Sbjct: 1142 CEDPGIPQYGSRIGFNFGI--GDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC- 1197
Query: 222 EIYCPAPPQIDNGII 236
C A + GI+
Sbjct: 1198 VAECGASATNNEGIL 1212
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/224 (24%), Positives = 77/224 (34%), Gaps = 56/224 (25%)
Query: 113 YITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK--WSTAVEFCKKKSCPNPGEIR 170
++ N F VG + +EC PGY + + LTCL + W+ + C+ C
Sbjct: 2194 FVIGNDFTVGQTISFECFPGYTLIGNSA--LTCLHGVSRNWNHPLPRCEAL-CGGNITAM 2250
Query: 171 NGQIDVPG---------------------GILFGATI----------------------- 186
NG I PG GI T+
Sbjct: 2251 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2310
Query: 187 -SFSCNTGYKLFGSTSSFCLIS-GSSVQWSDPLPECREIY----CPAPPQIDNGIIQGER 240
FS NT + STS+ LI S S Y C PP + N I E
Sbjct: 2311 GQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTED 2370
Query: 241 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
D + + Y C GFT++G + C + + + G PP C+
Sbjct: 2371 DEFEIGDIIRYQCLPGFTLVGNAILTCRL-GERLQMDGAPPVCQ 2413
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQWSDPLPECR 221
CP+PGE NG+ + G+T+ FSC+ Y L G+ S C I+ WSD P C+
Sbjct: 446 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 504
Query: 222 EIYCPAPPQIDNG 234
C + Q +G
Sbjct: 505 VKTCGSNLQGPSG 517
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
C +PG + G G G+TI + CN GY L GS+ C+ +G W PLP C
Sbjct: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCM-TGERRAWDYPLPSC 1370
Score = 39.3 bits (90), Expect = 0.007
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 15/89 (16%)
Query: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGAT------ISFSCNTGYKLFGSTSSFCLI-SG 208
E + SC NPG P G+L+G I +SC TGY L G C+ S
Sbjct: 131 EELQSSSCGNPGV-------PPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSV 183
Query: 209 SSVQWSDPLPECR-EIYCPAPPQIDNGII 236
++ W P+P CR E C + +GII
Sbjct: 184 NTASWDFPVPICRAEDACGGTMRGSSGII 212
Score = 38.9 bits (89), Expect = 0.009
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQ 212
AV C + E R G+ + G+++ F CN GY L GS + C + S Q
Sbjct: 1829 AVPRTSSTQCSSVPEPRFGR-RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1887
Query: 213 WSDPLPEC 220
W+D LP C
Sbjct: 1888 WNDSLPTC 1895
Score = 38.1 bits (87), Expect = 0.016
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
SCP P +G I + + G +SF C+ GY L G + C+ G +W+ P+P C
Sbjct: 2011 SCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCM-PGPVRRWNYPIPIC 2067
Score = 37.7 bits (86), Expect = 0.021
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Query: 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
CP P NG + G G Q++++ C G+T+IG ++ C ++ W+ P P C
Sbjct: 2184 CPDPRPFRNGFVIGNDFTVG--QTISFECFPGYTLIGNSALTC-LHGVSRNWNHPLPRC 2239
Score = 37.0 bits (84), Expect = 0.036
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 5/63 (7%)
Query: 239 ERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP--TV 296
E D + R + + C GF +IGE SI C NN +WS P C L++ P TV
Sbjct: 636 EGDGFSNRDVLRFECQFGFELIGEKSIVCQENN---QWSANIPICIFPCLSNFTAPMGTV 692
Query: 297 QKP 299
P
Sbjct: 693 LSP 695
Score = 36.6 bits (83), Expect = 0.047
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
Query: 160 KKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSS-VQWSDPLP 218
++SC +PG I NG + G+T+++ C+ GY L G ++ C++ W+ LP
Sbjct: 1658 RESCFDPGNIMNGT-RLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1716
Query: 219 EC 220
C
Sbjct: 1717 SC 1718
Score = 35.8 bits (81), Expect = 0.079
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
SC +PG +G+ G+T+SFSC++GY+L C + WS PLP C
Sbjct: 969 SCLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPLPTC 1023
Score = 35.4 bits (80), Expect = 0.10
Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 20/152 (13%)
Query: 217 LPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYC-TVNNDEGE 275
+P C + P+ G G + + SV + CN G+ + G +I C TV N +
Sbjct: 1830 VPRTSSTQCSSVPEPRFGRRIG--NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1887
Query: 276 WSGPPPEC---RGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTP 332
W+ P C G LT + K T ++ E + K T P +
Sbjct: 1888 WNDSLPTCIVPCGGILTKR------KGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQV 1941
Query: 333 VSRTTKH------FHETTPNKGS--GTTSGTT 356
VS T+H F++ N G+ SGTT
Sbjct: 1942 VSFATEHNWDSLDFYDGGDNNAPRLGSYSGTT 1973
Score = 33.9 bits (76), Expect = 0.30
Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 7/106 (6%)
Query: 178 GGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQ 237
G + G T+S + N + F S + V S L C + P PQ I
Sbjct: 1272 GASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCED---PGIPQFGYKI-- 1326
Query: 238 GERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
++ H+ ++ Y CN G+T+ G + C + + W P P C
Sbjct: 1327 SDQGHFA-GSTIIYGCNPGYTLHGSSLLKC-MTGERRAWDYPLPSC 1370
Score = 33.5 bits (75), Expect = 0.39
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGY-KLFGSTSSFCLISGSSVQWSDPLPEC 220
CP+PG N + G++IS C G+ K G+ + C++ V WS +P+C
Sbjct: 794 CPDPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 851
Score = 32.7 bits (73), Expect = 0.67
Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 8/78 (10%)
Query: 207 SGSSVQWSDPLPE-CREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSI 265
SG ++Q+S + CR+ P P NG G+ G +V + C+ G+ + GE I
Sbjct: 1474 SGFAIQFSSSVATACRD---PGVPM--NGTRNGDGREPG--DTVVFQCDPGYELQGEERI 1526
Query: 266 YCTVNNDEGEWSGPPPEC 283
C + W PP C
Sbjct: 1527 TCIQVENRYFWQPSPPVC 1544
Score = 32.3 bits (72), Expect = 0.88
Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 19/122 (15%)
Query: 171 NGQIDVPGGILFGATISFSCNTGYKLFGS-------TSSFCL-ISGSSVQWSD-PLPECR 221
NG P L G+ + + N G L+G+ S F + G ++ +S+ L C
Sbjct: 1086 NGSFTQPLARLTGSDLPPTINAG--LYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCE 1143
Query: 222 EIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPP 281
+ P PQ + I ++G ++T++C+ G+ + G I C + WS P P
Sbjct: 1144 D---PGIPQYGSRI----GFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLP 1195
Query: 282 EC 283
C
Sbjct: 1196 RC 1197
Score = 32.0 bits (71), Expect = 1.1
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 3/59 (5%)
Query: 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
CP P +GI G+R Y V++ C++G+++ G I C + W+ P P C
Sbjct: 2012 CPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITC-MPGPVRRWNYPIPIC 2067
Score = 30.4 bits (67), Expect = 3.3
Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
+C +PG NG + G G T+ F C+ GY+L G C+ + W P C
Sbjct: 1487 ACRDPGVPMNGTRNGDGREP-GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1544
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 108 bits (269), Expect = 1e-23
Identities = 81/256 (31%), Positives = 111/256 (43%), Gaps = 24/256 (9%)
Query: 34 GDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
G CG+P + N Q + G DTV+ Y+C F I IC + WS
Sbjct: 2646 GHCGIPELIVNGQ--VIGENYGYRDTVV-YQCNPGFRLIGSSVR--ICQQDHNWSGQLPS 2700
Query: 94 CNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWS 152
C SC P S + N F VV + C GY + K C N +WS
Sbjct: 2701 CVPVSCGHP-----GSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPT--KAQCQANRQWS 2753
Query: 153 TAVEFCKKKSCPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
CK +C +PG N + + G +G + + CN GY LFGS+ C +G
Sbjct: 2754 HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNG- 2812
Query: 210 SVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTV 269
QW PLPEC I C P N ++ GE+ Y + +V Y+C +++G+ S C +
Sbjct: 2813 --QWDKPLPECIMIDCGHPGVPPNAVLSGEK--YTFGSTVHYSCTGKRSLLGQSSRTCQL 2868
Query: 270 NNDEGEWSGPPPECRG 285
N G WSG P C G
Sbjct: 2869 N---GHWSGSQPHCSG 2881
Score = 105 bits (261), Expect = 1e-22
Identities = 87/288 (30%), Positives = 120/288 (41%), Gaps = 38/288 (13%)
Query: 25 VLLCLP----------AVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPG 74
VL+C P + DCG P PNA L G + + + Y C +
Sbjct: 2805 VLICQPNGQWDKPLPECIMIDCGHPGVPPNA--VLSGE-KYTFGSTVHYSCTGKRSLLG- 2860
Query: 75 EKDSVICLKGSQWSDIEEFCNR----SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECR 130
+ S C WS + C+ +C P S ++ + F + V Y C
Sbjct: 2861 -QSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQE-----SNFRTKSTVRYACD 2914
Query: 131 PGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSC 190
GY S + TCL N W+ CK C NPG NG++ G F +++ +SC
Sbjct: 2915 TGYILHGS--EERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSC 2972
Query: 191 NTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVT 250
GY L G + C +G+ WS LP C I C P NG+ G D Y Q+V+
Sbjct: 2973 MEGYILSGPSVRQCTANGT---WSGTLPNCTIISCGDPGIPANGLRYG--DDYVVGQNVS 3027
Query: 251 YACNKGFTM--IGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Y C G+TM G CT+N G WSG P CR ++T PP +
Sbjct: 3028 YMCQPGYTMELNGSRIRTCTIN---GTWSGVMPTCR--AVTCPTPPQI 3070
Score = 97.4 bits (241), Expect = 2e-20
Identities = 79/274 (28%), Positives = 120/274 (43%), Gaps = 29/274 (10%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKI-PGEKDSVICLKGSQWSDIEEFC 94
CG P N + T+F + Y C E ++ P + C WS C
Sbjct: 2945 CGNPGTTANGKVFRIDGTTFSSSVI--YSCMEGYILSGPSVRQ---CTANGTWSGTLPNC 2999
Query: 95 NR-SCEVP-TRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWS 152
SC P N Y+ VG V Y C+PGY E + S TC N WS
Sbjct: 3000 TIISCGDPGIPANGLRYGDDYV------VGQNVSYMCQPGYTMELNGSRIRTCTINGTWS 3053
Query: 153 TAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
+ C+ +CP P +I NG+++ +G +IS+ C+ GY+L C+ +G+
Sbjct: 3054 GVMPTCRAVTCPTPPQISNGRLE-GTNFDWGFSISYICSPGYELSFPAVLTCVGNGT--- 3109
Query: 213 WSDPLPECREIYCPAPPQIDNGI-IQGERD--HYGYRQSVTYACNKGFTMIGEHSIYCTV 269
WS +P+C +C P GI QG+R+ + Y+ V+++CN F ++G + C
Sbjct: 3110 WSGEVPQCLPKFCGDP-----GIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQA 3164
Query: 270 NNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVN 303
+G WSG P C + TS P V + + N
Sbjct: 3165 ---DGTWSGSSPHCIEPTQTSCENPGVPRHGSQN 3195
Score = 95.1 bits (235), Expect = 1e-19
Identities = 77/255 (30%), Positives = 107/255 (41%), Gaps = 25/255 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ----WSDIE 91
C P P+ + +T ++V+ + C+ F ++ G K S +C K S W
Sbjct: 2465 CSTPESPPHGY--IISQTGGQLNSVVRWACDRGF-RLVG-KSSAVCRKSSYGYHAWDAPV 2520
Query: 92 EFCNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK 150
C SC +P + + +T +Y VGT V Y C GYR C +
Sbjct: 2521 PACQAISCGIPKAPTNGGI----LTTDYL-VGTRVTYFCNDGYRLSSKELTTAVCQSDGT 2575
Query: 151 WST--AVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISG 208
WS C SC NG + +G+T F+C+ G+ L GS CL SG
Sbjct: 2576 WSNHNKTPRCVVISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSG 2634
Query: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCT 268
WS+ C +C P I NG + GE +YGYR +V Y CN GF +IG C
Sbjct: 2635 L---WSESETRCLAGHCGIPELIVNGQVIGE--NYGYRDTVVYQCNPGFRLIGSSVRIC- 2688
Query: 269 VNNDEGEWSGPPPEC 283
+ WSG P C
Sbjct: 2689 --QQDHNWSGQLPSC 2701
Score = 67.0 bits (162), Expect = 3e-11
Identities = 59/212 (27%), Positives = 89/212 (41%), Gaps = 33/212 (15%)
Query: 16 GELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGE 75
GE+P+ CLP GD G+P AQ EG+ SF + +++ C F+ +
Sbjct: 3112 GEVPQ-------CLPKFCGDPGIP-----AQGKREGK-SFIYQSEVSFSCNFPFILVGSS 3158
Query: 76 KDSVICLKGSQWSDIEEFC----NRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRP 131
+ IC WS C SCE P S + F VG+VV++ C+
Sbjct: 3159 --TRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF----GFQVGSVVQFHCKK 3212
Query: 132 GYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQI---DVPGGILFGATISF 188
G+ + S + TCL +L WS C SC P + + D+P G T+ +
Sbjct: 3213 GHLLQGSTTR--TCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPS---HGYTLIY 3267
Query: 189 SCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
+C G+ L G T + S W+ +P C
Sbjct: 3268 TCQPGFFLAGGTEH--RVCRSDNTWTGKVPIC 3297
Score = 65.1 bits (157), Expect = 1e-10
Identities = 73/275 (26%), Positives = 112/275 (40%), Gaps = 32/275 (11%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESF-VKIPGEKDSVICLKGSQWS-DIEEF 93
C PP + N + LEG T+F I+Y C + + P + C+ WS ++ +
Sbjct: 3064 CPTPPQISNGR--LEG-TNFDWGFSISYICSPGYELSFPAV---LTCVGNGTWSGEVPQC 3117
Query: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
+ C P Q F + V + C + S + C + WS
Sbjct: 3118 LPKFCGDP-----GIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTR--ICQADGTWSG 3170
Query: 154 AVEFC---KKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSS 210
+ C + SC NPG R+G + G G+ + F C G+ L GST+ CL
Sbjct: 3171 SSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL---PD 3227
Query: 211 VQWSDPLPECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACNKGFTMIG--EHSIYC 267
+ WS PEC C P + + G + +GY ++ Y C GF + G EH + C
Sbjct: 3228 LTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGY--TLIYTCQPGFFLAGGTEHRV-C 3284
Query: 268 TVNNDEGEWSGPPPECR-GKSLTSKVP-PTVQKPT 300
+N W+G P C G + K P P + P+
Sbjct: 3285 RSDN---TWTGKVPICEAGSKILVKDPRPALGTPS 3316
Score = 53.1 bits (126), Expect = 5e-07
Identities = 34/85 (40%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 161 KSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
+SCP+P RNG + + G TISF C GY L G+++ CL G S W+ PLP C
Sbjct: 2118 QSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALTCL-HGVSRNWNHPLPRC 2175
Query: 221 REIYCPAPPQIDNGII--QGERDHY 243
E C NG I G D Y
Sbjct: 2176 -EALCGGNITAMNGTIYSPGYPDEY 2199
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 5/75 (6%)
Query: 163 CPNPGEIRNG-QIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECR 221
C +PG + G +I GI G T++FSC++GY+L G++ CL G V WS PLP C
Sbjct: 1078 CEDPGIPQYGSRIGFNFGI--GDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC- 1133
Query: 222 EIYCPAPPQIDNGII 236
C A + GI+
Sbjct: 1134 VAECGASATNNEGIL 1148
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/224 (24%), Positives = 77/224 (34%), Gaps = 56/224 (25%)
Query: 113 YITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK--WSTAVEFCKKKSCPNPGEIR 170
++ N F VG + +EC PGY + + LTCL + W+ + C+ C
Sbjct: 2130 FVIGNDFTVGQTISFECFPGYTLIGNSA--LTCLHGVSRNWNHPLPRCEAL-CGGNITAM 2186
Query: 171 NGQIDVPG---------------------GILFGATI----------------------- 186
NG I PG GI T+
Sbjct: 2187 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2246
Query: 187 -SFSCNTGYKLFGSTSSFCLIS-GSSVQWSDPLPECREIY----CPAPPQIDNGIIQGER 240
FS NT + STS+ LI S S Y C PP + N I E
Sbjct: 2247 GQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTED 2306
Query: 241 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
D + + Y C GFT++G + C + + + G PP C+
Sbjct: 2307 DEFEIGDIIRYQCLPGFTLVGNAILTCRL-GERLQMDGAPPVCQ 2349
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQWSDPLPECR 221
CP+PGE NG+ + G+T+ FSC+ Y L G+ S C I+ WSD P C+
Sbjct: 382 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 440
Query: 222 EIYCPAPPQIDNG 234
C + Q +G
Sbjct: 441 VKTCGSNLQGPSG 453
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
C +PG + G G G+TI + CN GY L GS+ C+ +G W PLP C
Sbjct: 1250 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCM-TGERRAWDYPLPSC 1306
Score = 39.3 bits (90), Expect = 0.007
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 15/89 (16%)
Query: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGAT------ISFSCNTGYKLFGSTSSFCLI-SG 208
E + SC NPG P G+L+G I +SC TGY L G C+ S
Sbjct: 171 EELQSSSCGNPGV-------PPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSV 223
Query: 209 SSVQWSDPLPECR-EIYCPAPPQIDNGII 236
++ W P+P CR E C + +GII
Sbjct: 224 NTASWDFPVPICRAEDACGGTMRGSSGII 252
Score = 38.9 bits (89), Expect = 0.009
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQ 212
AV C + E R G+ + G+++ F CN GY L GS + C + S Q
Sbjct: 1765 AVPRTSSTQCSSVPEPRFGR-RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1823
Query: 213 WSDPLPEC 220
W+D LP C
Sbjct: 1824 WNDSLPTC 1831
Score = 38.1 bits (87), Expect = 0.016
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
SCP P +G I + + G +SF C+ GY L G + C+ G +W+ P+P C
Sbjct: 1947 SCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCM-PGPVRRWNYPIPIC 2003
Score = 37.7 bits (86), Expect = 0.021
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Query: 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
CP P NG + G G Q++++ C G+T+IG ++ C ++ W+ P P C
Sbjct: 2120 CPDPRPFRNGFVIGNDFTVG--QTISFECFPGYTLIGNSALTC-LHGVSRNWNHPLPRC 2175
Score = 37.0 bits (84), Expect = 0.036
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 5/63 (7%)
Query: 239 ERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP--TV 296
E D + R + + C GF +IGE SI C NN +WS P C L++ P TV
Sbjct: 572 EGDGFSNRDVLRFECQFGFELIGEKSIVCQENN---QWSANIPICIFPCLSNFTAPMGTV 628
Query: 297 QKP 299
P
Sbjct: 629 LSP 631
Score = 36.6 bits (83), Expect = 0.047
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
Query: 160 KKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSS-VQWSDPLP 218
++SC +PG I NG + G+T+++ C+ GY L G ++ C++ W+ LP
Sbjct: 1594 RESCFDPGNIMNGT-RLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1652
Query: 219 EC 220
C
Sbjct: 1653 SC 1654
Score = 35.8 bits (81), Expect = 0.079
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
SC +PG +G+ G+T+SFSC++GY+L C + WS PLP C
Sbjct: 905 SCLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPLPTC 959
Score = 35.4 bits (80), Expect = 0.10
Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 20/152 (13%)
Query: 217 LPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYC-TVNNDEGE 275
+P C + P+ G G + + SV + CN G+ + G +I C TV N +
Sbjct: 1766 VPRTSSTQCSSVPEPRFGRRIG--NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1823
Query: 276 WSGPPPEC---RGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTP 332
W+ P C G LT + K T ++ E + K T P +
Sbjct: 1824 WNDSLPTCIVPCGGILTKR------KGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQV 1877
Query: 333 VSRTTKH------FHETTPNKGS--GTTSGTT 356
VS T+H F++ N G+ SGTT
Sbjct: 1878 VSFATEHNWDSLDFYDGGDNNAPRLGSYSGTT 1909
Score = 33.9 bits (76), Expect = 0.30
Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 7/106 (6%)
Query: 178 GGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQ 237
G + G T+S + N + F S + V S L C + P PQ I
Sbjct: 1208 GASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCED---PGIPQFGYKI-- 1262
Query: 238 GERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
++ H+ ++ Y CN G+T+ G + C + + W P P C
Sbjct: 1263 SDQGHFA-GSTIIYGCNPGYTLHGSSLLKC-MTGERRAWDYPLPSC 1306
Score = 33.5 bits (75), Expect = 0.39
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGY-KLFGSTSSFCLISGSSVQWSDPLPEC 220
CP+PG N + G++IS C G+ K G+ + C++ V WS +P+C
Sbjct: 730 CPDPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 787
Score = 32.7 bits (73), Expect = 0.67
Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 8/78 (10%)
Query: 207 SGSSVQWSDPLPE-CREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSI 265
SG ++Q+S + CR+ P P NG G+ G +V + C+ G+ + GE I
Sbjct: 1410 SGFAIQFSSSVATACRD---PGVPM--NGTRNGDGREPG--DTVVFQCDPGYELQGEERI 1462
Query: 266 YCTVNNDEGEWSGPPPEC 283
C + W PP C
Sbjct: 1463 TCIQVENRYFWQPSPPVC 1480
Score = 32.3 bits (72), Expect = 0.88
Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 19/122 (15%)
Query: 171 NGQIDVPGGILFGATISFSCNTGYKLFGS-------TSSFCL-ISGSSVQWSD-PLPECR 221
NG P L G+ + + N G L+G+ S F + G ++ +S+ L C
Sbjct: 1022 NGSFTQPLARLTGSDLPPTINAG--LYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCE 1079
Query: 222 EIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPP 281
+ P PQ + I ++G ++T++C+ G+ + G I C + WS P P
Sbjct: 1080 D---PGIPQYGSRI----GFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLP 1131
Query: 282 EC 283
C
Sbjct: 1132 RC 1133
Score = 32.0 bits (71), Expect = 1.1
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 3/59 (5%)
Query: 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
CP P +GI G+R Y V++ C++G+++ G I C + W+ P P C
Sbjct: 1948 CPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITC-MPGPVRRWNYPIPIC 2003
Score = 30.4 bits (67), Expect = 3.3
Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
+C +PG NG + G G T+ F C+ GY+L G C+ + W P C
Sbjct: 1423 ACRDPGVPMNGTRNGDGREP-GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1480
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 108 bits (269), Expect = 1e-23
Identities = 81/256 (31%), Positives = 111/256 (43%), Gaps = 24/256 (9%)
Query: 34 GDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
G CG+P + N Q + G DTV+ Y+C F I IC + WS
Sbjct: 2815 GHCGIPELIVNGQ--VIGENYGYRDTVV-YQCNPGFRLIGSSVR--ICQQDHNWSGQLPS 2869
Query: 94 CNR-SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWS 152
C SC P S + N F VV + C GY + K C N +WS
Sbjct: 2870 CVPVSCGHP-----GSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPT--KAQCQANRQWS 2922
Query: 153 TAVEFCKKKSCPNPGEIRNGQIDVP---GGILFGATISFSCNTGYKLFGSTSSFCLISGS 209
CK +C +PG N + + G +G + + CN GY LFGS+ C +G
Sbjct: 2923 HPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNG- 2981
Query: 210 SVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTV 269
QW PLPEC I C P N ++ GE+ Y + +V Y+C +++G+ S C +
Sbjct: 2982 --QWDKPLPECIMIDCGHPGVPPNAVLSGEK--YTFGSTVHYSCTGKRSLLGQSSRTCQL 3037
Query: 270 NNDEGEWSGPPPECRG 285
N G WSG P C G
Sbjct: 3038 N---GHWSGSQPHCSG 3050
Score = 105 bits (261), Expect = 1e-22
Identities = 87/288 (30%), Positives = 120/288 (41%), Gaps = 38/288 (13%)
Query: 25 VLLCLP----------AVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPG 74
VL+C P + DCG P PNA L G + + + Y C +
Sbjct: 2974 VLICQPNGQWDKPLPECIMIDCGHPGVPPNA--VLSGE-KYTFGSTVHYSCTGKRSLLG- 3029
Query: 75 EKDSVICLKGSQWSDIEEFCNR----SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECR 130
+ S C WS + C+ +C P S ++ + F + V Y C
Sbjct: 3030 -QSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQE-----SNFRTKSTVRYACD 3083
Query: 131 PGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSC 190
GY S + TCL N W+ CK C NPG NG++ G F +++ +SC
Sbjct: 3084 TGYILHGS--EERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSC 3141
Query: 191 NTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVT 250
GY L G + C +G+ WS LP C I C P NG+ G D Y Q+V+
Sbjct: 3142 MEGYILSGPSVRQCTANGT---WSGTLPNCTIISCGDPGIPANGLRYG--DDYVVGQNVS 3196
Query: 251 YACNKGFTM--IGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTV 296
Y C G+TM G CT+N G WSG P CR ++T PP +
Sbjct: 3197 YMCQPGYTMELNGSRIRTCTIN---GTWSGVMPTCR--AVTCPTPPQI 3239
Score = 98.2 bits (243), Expect = 1e-20
Identities = 78/256 (30%), Positives = 110/256 (42%), Gaps = 25/256 (9%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
CG+P N T + T +TY C + + E + +C WS+ +
Sbjct: 2632 CGIPKAPTNGGILT---TDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNK--T 2686
Query: 96 RSCEVPT--RLNSASLKQP---YITQNYFPVGTVVEYECRPGYRREPSLSP-KLTCLQNL 149
C V T +NS L+ + +++ T V + C PGY L P + CL N
Sbjct: 2687 PRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYH---GLGPASIECLPNG 2743
Query: 150 KWSTAVE--FCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLIS 207
WS E +C+ SC NG + +G+T F+C+ G+ L GS CL S
Sbjct: 2744 TWSWRNERPYCQIISCGELPTPPNGN-KIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS 2802
Query: 208 GSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYC 267
G WS+ C +C P I NG + GE +YGYR +V Y CN GF +IG C
Sbjct: 2803 GL---WSESETRCLAGHCGIPELIVNGQVIGE--NYGYRDTVVYQCNPGFRLIGSSVRIC 2857
Query: 268 TVNNDEGEWSGPPPEC 283
+ WSG P C
Sbjct: 2858 ---QQDHNWSGQLPSC 2870
Score = 97.4 bits (241), Expect = 2e-20
Identities = 79/274 (28%), Positives = 120/274 (43%), Gaps = 29/274 (10%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKI-PGEKDSVICLKGSQWSDIEEFC 94
CG P N + T+F + Y C E ++ P + C WS C
Sbjct: 3114 CGNPGTTANGKVFRIDGTTFSSSVI--YSCMEGYILSGPSVRQ---CTANGTWSGTLPNC 3168
Query: 95 NR-SCEVP-TRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWS 152
SC P N Y+ VG V Y C+PGY E + S TC N WS
Sbjct: 3169 TIISCGDPGIPANGLRYGDDYV------VGQNVSYMCQPGYTMELNGSRIRTCTINGTWS 3222
Query: 153 TAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQ 212
+ C+ +CP P +I NG+++ +G +IS+ C+ GY+L C+ +G+
Sbjct: 3223 GVMPTCRAVTCPTPPQISNGRLE-GTNFDWGFSISYICSPGYELSFPAVLTCVGNGT--- 3278
Query: 213 WSDPLPECREIYCPAPPQIDNGI-IQGERD--HYGYRQSVTYACNKGFTMIGEHSIYCTV 269
WS +P+C +C P GI QG+R+ + Y+ V+++CN F ++G + C
Sbjct: 3279 WSGEVPQCLPKFCGDP-----GIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQA 3333
Query: 270 NNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVN 303
+G WSG P C + TS P V + + N
Sbjct: 3334 ---DGTWSGSSPHCIEPTQTSCENPGVPRHGSQN 3364
Score = 67.0 bits (162), Expect = 3e-11
Identities = 59/212 (27%), Positives = 89/212 (41%), Gaps = 33/212 (15%)
Query: 16 GELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGE 75
GE+P+ CLP GD G+P AQ EG+ SF + +++ C F+ +
Sbjct: 3281 GEVPQ-------CLPKFCGDPGIP-----AQGKREGK-SFIYQSEVSFSCNFPFILVGSS 3327
Query: 76 KDSVICLKGSQWSDIEEFC----NRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRP 131
+ IC WS C SCE P S + F VG+VV++ C+
Sbjct: 3328 --TRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTF----GFQVGSVVQFHCKK 3381
Query: 132 GYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQI---DVPGGILFGATISF 188
G+ + S + TCL +L WS C SC P + + D+P G T+ +
Sbjct: 3382 GHLLQGSTTR--TCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPS---HGYTLIY 3436
Query: 189 SCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
+C G+ L G T + S W+ +P C
Sbjct: 3437 TCQPGFFLAGGTEH--RVCRSDNTWTGKVPIC 3466
Score = 65.1 bits (157), Expect = 1e-10
Identities = 73/275 (26%), Positives = 112/275 (40%), Gaps = 32/275 (11%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESF-VKIPGEKDSVICLKGSQWS-DIEEF 93
C PP + N + LEG T+F I+Y C + + P + C+ WS ++ +
Sbjct: 3233 CPTPPQISNGR--LEG-TNFDWGFSISYICSPGYELSFPAV---LTCVGNGTWSGEVPQC 3286
Query: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
+ C P Q F + V + C + S + C + WS
Sbjct: 3287 LPKFCGDP-----GIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTR--ICQADGTWSG 3339
Query: 154 AVEFC---KKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSS 210
+ C + SC NPG R+G + G G+ + F C G+ L GST+ CL
Sbjct: 3340 SSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL---PD 3396
Query: 211 VQWSDPLPECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACNKGFTMIG--EHSIYC 267
+ WS PEC C P + + G + +GY ++ Y C GF + G EH + C
Sbjct: 3397 LTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGY--TLIYTCQPGFFLAGGTEHRV-C 3453
Query: 268 TVNNDEGEWSGPPPECR-GKSLTSKVP-PTVQKPT 300
+N W+G P C G + K P P + P+
Sbjct: 3454 RSDN---TWTGKVPICEAGSKILVKDPRPALGTPS 3485
Score = 53.1 bits (126), Expect = 5e-07
Identities = 34/85 (40%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 161 KSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
+SCP+P RNG + + G TISF C GY L G+++ CL G S W+ PLP C
Sbjct: 2222 QSCPDPRPFRNGFV-IGNDFTVGQTISFECFPGYTLIGNSALTCL-HGVSRNWNHPLPRC 2279
Query: 221 REIYCPAPPQIDNGII--QGERDHY 243
E C NG I G D Y
Sbjct: 2280 -EALCGGNITAMNGTIYSPGYPDEY 2303
Score = 52.8 bits (125), Expect = 6e-07
Identities = 36/124 (29%), Positives = 52/124 (41%), Gaps = 6/124 (4%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQ-WSDPLPECR 221
C P +G I G + + ++C+ G++L G +S+ C S W P+P C+
Sbjct: 2569 CSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQ 2628
Query: 222 EIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWS--GP 279
I C P NG I G R VTY CN G+ + + V +G WS
Sbjct: 2629 AISCGIPKAPTNGGILTTDYLVGTR--VTYFCNDGY-RLSSKELTTAVCQSDGTWSNHNK 2685
Query: 280 PPEC 283
P C
Sbjct: 2686 TPRC 2689
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 5/75 (6%)
Query: 163 CPNPGEIRNG-QIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECR 221
C +PG + G +I GI G T++FSC++GY+L G++ CL G V WS PLP C
Sbjct: 1182 CEDPGIPQYGSRIGFNFGI--GDTLTFSCSSGYRLEGTSEIICLGGGRRV-WSAPLPRC- 1237
Query: 222 EIYCPAPPQIDNGII 236
C A + GI+
Sbjct: 1238 VAECGASATNNEGIL 1252
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/224 (24%), Positives = 77/224 (34%), Gaps = 56/224 (25%)
Query: 113 YITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLK--WSTAVEFCKKKSCPNPGEIR 170
++ N F VG + +EC PGY + + LTCL + W+ + C+ C
Sbjct: 2234 FVIGNDFTVGQTISFECFPGYTLIGNSA--LTCLHGVSRNWNHPLPRCEAL-CGGNITAM 2290
Query: 171 NGQIDVPG---------------------GILFGATI----------------------- 186
NG I PG GI T+
Sbjct: 2291 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2350
Query: 187 -SFSCNTGYKLFGSTSSFCLIS-GSSVQWSDPLPECREIY----CPAPPQIDNGIIQGER 240
FS NT + STS+ LI S S Y C PP + N I E
Sbjct: 2351 GQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTED 2410
Query: 241 DHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
D + + Y C GFT++G + C + + + G PP C+
Sbjct: 2411 DEFEIGDIIRYQCLPGFTLVGNAILTCRL-GERLQMDGAPPVCQ 2453
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/73 (35%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQWSDPLPECR 221
CP+PGE NG+ + G+T+ FSC+ Y L G+ S C I+ WSD P C+
Sbjct: 486 CPDPGEPENGK-RIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCK 544
Query: 222 EIYCPAPPQIDNG 234
C + Q +G
Sbjct: 545 VKTCGSNLQGPSG 557
Score = 41.2 bits (95), Expect = 0.002
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
C +PG + G G G+TI + CN GY L GS+ C+ +G W PLP C
Sbjct: 1354 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCM-TGERRAWDYPLPSC 1410
Score = 39.3 bits (90), Expect = 0.007
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 15/89 (16%)
Query: 156 EFCKKKSCPNPGEIRNGQIDVPGGILFGAT------ISFSCNTGYKLFGSTSSFCLI-SG 208
E + SC NPG P G+L+G I +SC TGY L G C+ S
Sbjct: 171 EELQSSSCGNPGV-------PPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSV 223
Query: 209 SSVQWSDPLPECR-EIYCPAPPQIDNGII 236
++ W P+P CR E C + +GII
Sbjct: 224 NTASWDFPVPICRAEDACGGTMRGSSGII 252
Score = 38.9 bits (89), Expect = 0.009
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 2/68 (2%)
Query: 154 AVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFC-LISGSSVQ 212
AV C + E R G+ + G+++ F CN GY L GS + C + S Q
Sbjct: 1869 AVPRTSSTQCSSVPEPRFGR-RIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1927
Query: 213 WSDPLPEC 220
W+D LP C
Sbjct: 1928 WNDSLPTC 1935
Score = 38.1 bits (87), Expect = 0.016
Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
SCP P +G I + + G +SF C+ GY L G + C+ G +W+ P+P C
Sbjct: 2051 SCPEPQTPSSG-IKIGDRYMVGDVVSFQCDQGYSLQGHSHITCM-PGPVRRWNYPIPIC 2107
Score = 37.7 bits (86), Expect = 0.021
Identities = 18/59 (30%), Positives = 30/59 (50%), Gaps = 3/59 (5%)
Query: 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
CP P NG + G G Q++++ C G+T+IG ++ C ++ W+ P P C
Sbjct: 2224 CPDPRPFRNGFVIGNDFTVG--QTISFECFPGYTLIGNSALTC-LHGVSRNWNHPLPRC 2279
Score = 37.0 bits (84), Expect = 0.036
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 5/63 (7%)
Query: 239 ERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPP--TV 296
E D + R + + C GF +IGE SI C NN +WS P C L++ P TV
Sbjct: 676 EGDGFSNRDVLRFECQFGFELIGEKSIVCQENN---QWSANIPICIFPCLSNFTAPMGTV 732
Query: 297 QKP 299
P
Sbjct: 733 LSP 735
Score = 36.6 bits (83), Expect = 0.047
Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 2/62 (3%)
Query: 160 KKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSS-VQWSDPLP 218
++SC +PG I NG + G+T+++ C+ GY L G ++ C++ W+ LP
Sbjct: 1698 RESCFDPGNIMNGT-RLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALP 1756
Query: 219 EC 220
C
Sbjct: 1757 SC 1758
Score = 35.8 bits (81), Expect = 0.079
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
SC +PG +G+ G+T+SFSC++GY+L C + WS PLP C
Sbjct: 1009 SCLDPGIPVHGR-RYGHDFSIGSTVSFSCDSGYRLSHEEPLLC---EKNHWWSHPLPTC 1063
Score = 35.4 bits (80), Expect = 0.10
Identities = 39/152 (25%), Positives = 59/152 (38%), Gaps = 20/152 (13%)
Query: 217 LPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYC-TVNNDEGE 275
+P C + P+ G G + + SV + CN G+ + G +I C TV N +
Sbjct: 1870 VPRTSSTQCSSVPEPRFGRRIG--NEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQ 1927
Query: 276 WSGPPPEC---RGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTP 332
W+ P C G LT + K T ++ E + K T P +
Sbjct: 1928 WNDSLPTCIVPCGGILTKR------KGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQV 1981
Query: 333 VSRTTKH------FHETTPNKGS--GTTSGTT 356
VS T+H F++ N G+ SGTT
Sbjct: 1982 VSFATEHNWDSLDFYDGGDNNAPRLGSYSGTT 2013
Score = 33.9 bits (76), Expect = 0.30
Identities = 27/106 (25%), Positives = 43/106 (40%), Gaps = 7/106 (6%)
Query: 178 GGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQ 237
G + G T+S + N + F S + V S L C + P PQ I
Sbjct: 1312 GASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCED---PGIPQFGYKI-- 1366
Query: 238 GERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
++ H+ ++ Y CN G+T+ G + C + + W P P C
Sbjct: 1367 SDQGHFA-GSTIIYGCNPGYTLHGSSLLKC-MTGERRAWDYPLPSC 1410
Score = 33.5 bits (75), Expect = 0.39
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGY-KLFGSTSSFCLISGSSVQWSDPLPEC 220
CP+PG N + G++IS C G+ K G+ + C++ V WS +P+C
Sbjct: 834 CPDPGIPINAR-RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKC 891
Score = 32.7 bits (73), Expect = 0.67
Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 8/78 (10%)
Query: 207 SGSSVQWSDPLPE-CREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSI 265
SG ++Q+S + CR+ P P NG G+ G +V + C+ G+ + GE I
Sbjct: 1514 SGFAIQFSSSVATACRD---PGVPM--NGTRNGDGREPG--DTVVFQCDPGYELQGEERI 1566
Query: 266 YCTVNNDEGEWSGPPPEC 283
C + W PP C
Sbjct: 1567 TCIQVENRYFWQPSPPVC 1584
Score = 32.3 bits (72), Expect = 0.88
Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 19/122 (15%)
Query: 171 NGQIDVPGGILFGATISFSCNTGYKLFGS-------TSSFCL-ISGSSVQWSD-PLPECR 221
NG P L G+ + + N G L+G+ S F + G ++ +S+ L C
Sbjct: 1126 NGSFTQPLARLTGSDLPPTINAG--LYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCE 1183
Query: 222 EIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPP 281
+ P PQ + I ++G ++T++C+ G+ + G I C + WS P P
Sbjct: 1184 D---PGIPQYGSRI----GFNFGIGDTLTFSCSSGYRLEGTSEIIC-LGGGRRVWSAPLP 1235
Query: 282 EC 283
C
Sbjct: 1236 RC 1237
Score = 32.0 bits (71), Expect = 1.1
Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 3/59 (5%)
Query: 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
CP P +GI G+R Y V++ C++G+++ G I C + W+ P P C
Sbjct: 2052 CPEPQTPSSGIKIGDR--YMVGDVVSFQCDQGYSLQGHSHITC-MPGPVRRWNYPIPIC 2107
Score = 30.4 bits (67), Expect = 3.3
Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 1/59 (1%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
+C +PG NG + G G T+ F C+ GY+L G C+ + W P C
Sbjct: 1527 ACRDPGVPMNGTRNGDGREP-GDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVC 1584
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 107 bits (267), Expect = 2e-23
Identities = 84/280 (30%), Positives = 125/280 (44%), Gaps = 33/280 (11%)
Query: 28 CLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQW 87
CL G G+P A L G F V+ Y C S I D+ +C + S W
Sbjct: 2855 CLAISCGHPGVP-----ANAVLTGEL-FTYGAVVHYSCRGSESLIGN--DTRVCQEDSHW 2906
Query: 88 SDIEEFCNRS----CEVP-TRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPK 142
S C + C P T + + L + T++ ++ + C G++ S P+
Sbjct: 2907 SGALPHCTGNNPGFCGDPGTPAHGSRLGDDFKTKS------LLRFSCEMGHQLRGS--PE 2958
Query: 143 LTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSS 202
TCL N WS C+ SC NPG NG I GILF +++ ++C GYK G +
Sbjct: 2959 RTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTR 3018
Query: 203 FCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTM--I 260
C +G+ W+ P+C I C P + NGI G + + ++V+Y CN G+ M +
Sbjct: 3019 HCTANGT---WTGTAPDCTIISCGDPGTLANGIQFG--TDFTFNKTVSYQCNPGYVMEAV 3073
Query: 261 GEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPT 300
+I CT +G W+ P C K++ PP VQ T
Sbjct: 3074 TSATIRCT---KDGRWNPSKPVC--KAVLCPQPPPVQNGT 3108
Score = 101 bits (252), Expect = 1e-21
Identities = 67/209 (32%), Positives = 100/209 (47%), Gaps = 22/209 (10%)
Query: 81 CLKGSQWSDIEEFCNRS-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSL 139
CL WS E C C P + + +I+ + F V Y+C PG+R +
Sbjct: 2663 CLANGLWSGSETRCLAGHCGSPDPIVNG-----HISGDGFSYRDTVVYQCNPGFRLVGT- 2716
Query: 140 SPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGAT--ISFSCNTGYKLF 197
S ++ CLQ+ KWS C +C +PG +G G F ++F+CNTGY L
Sbjct: 2717 SVRI-CLQDHKWSGQTPVCVPITCGHPGNPAHG---FTNGSEFNLNDVVNFTCNTGYLLQ 2772
Query: 198 GSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGER---DHYGYRQSVTYACN 254
G + + C +G QWS PLP CR + C P ++N I G++ + + Y S+ Y C
Sbjct: 2773 GVSRAQCRSNG---QWSSPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCK 2829
Query: 255 KGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
KGF ++G ++ C N G W P+C
Sbjct: 2830 KGFYLLGSSALTCMAN---GLWDRSLPKC 2855
Score = 99.8 bits (247), Expect = 4e-21
Identities = 74/259 (28%), Positives = 118/259 (45%), Gaps = 25/259 (9%)
Query: 34 GDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEF 93
G CG P + N + +G + DTV+ Y+C F ++ G ICL+ +WS
Sbjct: 2679 GHCGSPDPIVNGHISGDGFSY--RDTVV-YQCNPGF-RLVGTSVR-ICLQDHKWSGQTPV 2733
Query: 94 CNRSCEVP-TRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWS 152
C VP T + + + + F + VV + C GY + + C N +WS
Sbjct: 2734 C-----VPITCGHPGNPAHGFTNGSEFNLNDVVNFTCNTGYLLQGV--SRAQCRSNGQWS 2786
Query: 153 TAVEFCKKKSCPNPG----EIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISG 208
+ + C+ +C +PG IR+GQ + P +G +I + C G+ L GS++ C+ +G
Sbjct: 2787 SPLPTCRVVNCSDPGFVENAIRHGQQNFPESFEYGMSILYHCKKGFYLLGSSALTCMANG 2846
Query: 209 SSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCT 268
W LP+C I C P N ++ GE YG V Y+C ++IG + C
Sbjct: 2847 L---WDRSLPKCLAISCGHPGVPANAVLTGELFTYG--AVVHYSCRGSESLIGNDTRVC- 2900
Query: 269 VNNDEGEWSGPPPECRGKS 287
++ WSG P C G +
Sbjct: 2901 --QEDSHWSGALPHCTGNN 2917
Score = 93.2 bits (230), Expect = 4e-19
Identities = 81/264 (30%), Positives = 109/264 (41%), Gaps = 41/264 (15%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSD------ 89
CG+P N + G F D+ + Y+C E F ++ + +C + WS+
Sbjct: 2496 CGIPESPGNG--SFTGN-EFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPT 2552
Query: 90 --------IEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSP 141
IE S V RL S SL + G V C PGY E
Sbjct: 2553 CKPVACPSIE--AQLSEHVIWRLVSGSLNE---------YGAQVLLSCSPGYYLEGWRL- 2600
Query: 142 KLTCLQNLKWSTAVE--FCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGS 199
L C N W+ E C+ SC + NG + ++GAT F+CNTGY L GS
Sbjct: 2601 -LRCQANGTWNIGDERPSCRVISCGSLSFPPNGN-KIGTLTVYGATAIFTCNTGYTLVGS 2658
Query: 200 TSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTM 259
CL +G WS C +C +P I NG I G D + YR +V Y CN GF +
Sbjct: 2659 HVRECLANG---LWSGSETRCLAGHCGSPDPIVNGHISG--DGFSYRDTVVYQCNPGFRL 2713
Query: 260 IGEHSIYCTVNNDEGEWSGPPPEC 283
+G C + +WSG P C
Sbjct: 2714 VGTSVRICL---QDHKWSGQTPVC 2734
Score = 90.9 bits (224), Expect = 2e-18
Identities = 49/165 (29%), Positives = 78/165 (47%), Gaps = 9/165 (5%)
Query: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPG 178
F V Y+C PGY E S + C ++ +W+ + CK CP P ++NG ++
Sbjct: 3054 FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVLCPQPPPVQNGTVE-GS 3112
Query: 179 GILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQG 238
+G++IS+SC GY+L S S+ G V W +P+C ++C P G + G
Sbjct: 3113 DFRWGSSISYSCMDGYQL--SHSAILSCEGRGV-WKGEIPQCLPVFCGDPGIPAEGRLSG 3169
Query: 239 ERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
+ + Y+ V + C F ++G C +G WSG P C
Sbjct: 3170 K--SFTYKSEVFFQCKSPFILVGSSRRVCQA---DGTWSGIQPTC 3209
Score = 68.9 bits (167), Expect = 8e-12
Identities = 62/251 (24%), Positives = 105/251 (41%), Gaps = 39/251 (15%)
Query: 16 GELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGE 75
GE+P+ CLP GD G+P A+ L G+ SF + + ++C+ F+ +
Sbjct: 3146 GEIPQ-------CLPVFCGDPGIP-----AEGRLSGK-SFTYKSEVFFQCKSPFILVGSS 3192
Query: 76 KDSVICLKGSQWSDIEEFC----NRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRP 131
+ +C WS I+ C + +C P + + + VG+ V + CR
Sbjct: 3193 RR--VCQADGTWSGIQPTCIDPAHNTCPDPGTPHFGIQN----SSRGYEVGSTVFFRCRK 3246
Query: 132 GYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCN 191
GY + S + TCL NL WS C +C P + + FG T+ ++C+
Sbjct: 3247 GYHIQGSTT--RTCLANLTWSGIQTECIPHACRQPETPAHADVRAIDLPTFGYTLVYTCH 3304
Query: 192 TGYKLFGSTSSFCLISGSSVQWSDPLPEC-----REI-----YCPAPPQI--DNGIIQGE 239
G+ L G + + ++W+ P C RE+ P P + N + +G
Sbjct: 3305 PGFFLAGGSEH--RTCKADMKWTGKSPVCKSKGVREVNETVTKTPVPSDVFFVNSLWKGY 3362
Query: 240 RDHYGYRQSVT 250
++ G RQ T
Sbjct: 3363 YEYLGKRQPAT 3373
Score = 60.5 bits (145), Expect = 3e-09
Identities = 71/324 (21%), Positives = 118/324 (36%), Gaps = 77/324 (23%)
Query: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
CG P + N ++ T F + ++Y+C +V ++ C K +W+ + C
Sbjct: 3038 CGDPGTLANG---IQFGTDFTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCK 3094
Query: 96 RS-CEVPTRLNSASLKQPYITQNYFPVGTVVEYECR------------------------ 130
C P + + +++ + F G+ + Y C
Sbjct: 3095 AVLCPQPPPVQNGTVEG-----SDFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIP 3149
Query: 131 ---------PGYRREPSLSPKL-----------------------TCLQNLKWSTAVEFC 158
PG E LS K C + WS C
Sbjct: 3150 QCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTC 3209
Query: 159 ---KKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD 215
+CP+PG G + G G+T+ F C GY + GST+ CL +++ WS
Sbjct: 3210 IDPAHNTCPDPGTPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTCL---ANLTWSG 3266
Query: 216 PLPECREIYCPAPPQIDNGIIQG-ERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG 274
EC C P + ++ + +GY ++ Y C+ GF + G S + T D
Sbjct: 3267 IQTECIPHACRQPETPAHADVRAIDLPTFGY--TLVYTCHPGFFLAG-GSEHRTCKADM- 3322
Query: 275 EWSGPPPECRGKSLTSKVPPTVQK 298
+W+G P C+ K + +V TV K
Sbjct: 3323 KWTGKSPVCKSKGV-REVNETVTK 3345
Score = 58.2 bits (139), Expect = 1e-08
Identities = 53/198 (26%), Positives = 81/198 (40%), Gaps = 23/198 (11%)
Query: 121 VGTVVEYECRPGYRREPSLSPKLTCLQN----LKWSTAVEFCKKKSCPNPGEIRNGQIDV 176
VG+ V Y C+PGYR TC +N +W + C+ SC P NG
Sbjct: 2452 VGSKVHYFCKPGYRMVG--HSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSF-T 2508
Query: 177 PGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSD--PLPECREIYCPA-PPQIDN 233
+ + + C+ G+KL S + + + WS+ P C+ + CP+ Q+
Sbjct: 2509 GNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGL-WSNKGKPPTCKPVACPSIEAQLSE 2567
Query: 234 GII----QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWS--GPPPECRGKS 287
+I G + YG V +C+ G+ + G + C N G W+ P CR S
Sbjct: 2568 HVIWRLVSGSLNEYG--AQVLLSCSPGYYLEGWRLLRCQAN---GTWNIGDERPSCRVIS 2622
Query: 288 LTS-KVPPTVQKPTTVNV 304
S PP K T+ V
Sbjct: 2623 CGSLSFPPNGNKIGTLTV 2640
Score = 48.5 bits (114), Expect = 1e-05
Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 9/129 (6%)
Query: 154 AVEFCKK--KSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLI-SGSS 210
A+EF +K ++C +PG I NG V G+TI++ C++GYK+ +S C+I +
Sbjct: 1554 AIEFKEKPREACFDPGNIMNGT-RVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGK 1612
Query: 211 VQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYR--QSVTYACN--KGFTMIGEHSIY 266
W LP C C G++ + Y Q Y+ K F + G+ + +
Sbjct: 1613 PSWDQVLPSC-NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYF 1671
Query: 267 CTVNNDEGE 275
T ND E
Sbjct: 1672 QTALNDLAE 1680
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 1/75 (1%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCL-ISGSSVQWSDPLPECR 221
CP+PG NG+ GA + FSC Y L GS S C ++ + WSD P CR
Sbjct: 349 CPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQGSKSITCQRVTETLAAWSDHRPICR 408
Query: 222 EIYCPAPPQIDNGII 236
C + + +G+I
Sbjct: 409 ARTCGSNLRGPSGVI 423
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/69 (37%), Positives = 32/69 (46%), Gaps = 6/69 (8%)
Query: 156 EFCKKKSCPNPGEIRNGQIDVPGGILF--GATISFSCNTGYKLFGSTSSFCLIS-GSSVQ 212
E +C NPGEI G + G F G I +SC GY L G C++S G+
Sbjct: 138 EVLPSHTCGNPGEILKGVLH---GTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGAS 194
Query: 213 WSDPLPECR 221
W P P CR
Sbjct: 195 WDFPAPFCR 203
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 160 KKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGY-KLFGSTSSFCLISGSSVQWSDPLP 218
+ C +PG NG+ L G+++SF C+ G+ K GS S C++ +V WS +P
Sbjct: 695 QNECHDPGIPINGR-RFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVP 753
Query: 219 ECREIYCPAPPQIDNGII 236
C E C +G+I
Sbjct: 754 RC-EAPCGGHLTASSGVI 770
Score = 40.0 bits (92), Expect = 0.004
Identities = 19/38 (50%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Query: 183 GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
G +++FSC GY+L G+T CL G V WS PLP C
Sbjct: 1065 GDSLTFSCFLGYRLEGATKLTCLGGGRRV-WSAPLPRC 1101
Score = 39.7 bits (91), Expect = 0.005
Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 163 CPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
C +PG G G + +SCN GY + GS + CL SG W PLP C
Sbjct: 1218 CEDPGIPNYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTCL-SGDRRVWDKPLPSC 1274
Score = 38.9 bits (89), Expect = 0.009
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 183 GATISFSCNTGYKLFGSTSSFC-LISGSSVQWSDPLPEC 220
G+ + F CN GY L GST+ C + + QW+D +P C
Sbjct: 1761 GSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
Score = 38.9 bits (89), Expect = 0.009
Identities = 35/129 (27%), Positives = 50/129 (38%), Gaps = 17/129 (13%)
Query: 161 KSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
++CP+P +NG + + G ++SF C GY L G C G + W+ P P C
Sbjct: 2086 QNCPDPPPFQNGYM-INSDYSVGQSVSFECYPGYILIGHPVLTCQ-HGINRNWNYPFPRC 2143
Query: 221 REIYCPAPPQIDNGII--QGERDHYGYRQSVTYACNKGFTMIGEHSIYC--------TVN 270
+ C NG I G D Y + C T+ H +Y VN
Sbjct: 2144 -DAPCGYNVTSQNGTIYSPGFPDEY----PILKDCIWLITVPPGHGVYINFTLLQTEAVN 2198
Query: 271 NDEGEWSGP 279
+ W GP
Sbjct: 2199 DYIAVWDGP 2207
Score = 38.5 bits (88), Expect = 0.012
Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 6/77 (7%)
Query: 207 SGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIY 266
SG S+Q+S + C P NG G+ G +VT+ C+ G+ + G+ I
Sbjct: 1378 SGFSIQFSTSIAAT----CNDPGMPQNGTRYGDSREAG--DTVTFQCDPGYQLQGQAKIT 1431
Query: 267 CTVNNDEGEWSGPPPEC 283
C N+ W PP C
Sbjct: 1432 CVQLNNRFFWQPDPPTC 1448
Score = 37.4 bits (85), Expect = 0.027
Identities = 19/59 (32%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
CP PP NG + Y QSV++ C G+ +IG H + + W+ P P C
Sbjct: 2088 CPDPPPFQNGYMINS--DYSVGQSVSFECYPGYILIG-HPVLTCQHGINRNWNYPFPRC 2143
Score = 35.4 bits (80), Expect = 0.10
Identities = 52/231 (22%), Positives = 86/231 (37%), Gaps = 31/231 (13%)
Query: 61 ITYKCEESFVKIPGEKDSVICLKGSQ--WSDIEEFCNRSCEVPTRLNSASLKQPYITQNY 118
+++ C++ FVK G + L+ WS C C +S + P Y
Sbjct: 720 VSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPG-WPGY 778
Query: 119 FPVGTVVEY--ECRPGYRREPSLSPKLTCLQNLKWSTA-VEFCKKKSCPNPGEIRNGQID 175
+ E+ E +PG+ + + T + + T V S P GE Q
Sbjct: 779 YKDSLHCEWIIEAKPGHSIKITFDRFQT---EVNYDTLEVRDGPASSSPLIGEYHGTQAP 835
Query: 176 VPGGILFGATISFSCNTG---YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQID 232
F +TG Y LF + +S I G + + E P P
Sbjct: 836 -----------QFLISTGNFMYLLFTTDNSRSSI-GFLIHYESVTLESDSCLDPGIPV-- 881
Query: 233 NGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
NG G +G R +VT++C+ G+T+ + + C N+ +W+ P C
Sbjct: 882 NGHRHG--GDFGIRSTVTFSCDPGYTLSDDEPLVCERNH---QWNHALPSC 927
Score = 35.0 bits (79), Expect = 0.14
Identities = 16/68 (23%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Query: 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
C PP + + E D + V Y C+ G+T++G + C +++ + ++ G P C
Sbjct: 2259 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSS-QLQFEGSLPTCE 2317
Query: 285 GKSLTSKV 292
+ ++V
Sbjct: 2318 AQCPANEV 2325
Score = 34.3 bits (77), Expect = 0.23
Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 10/51 (19%)
Query: 242 HYGYR---------QSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
+YGYR V Y+CN G+ M G +++ C ++ D W P P C
Sbjct: 1225 NYGYRIRDEGHFTDTVVLYSCNPGYAMHGSNTLTC-LSGDRRVWDKPLPSC 1274
Score = 33.9 bits (76), Expect = 0.30
Identities = 14/36 (38%), Positives = 20/36 (55%), Gaps = 3/36 (8%)
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
++T+ C F ++GE I C NN +WSG P C
Sbjct: 549 TLTFECPAAFELVGERVITCQQNN---QWSGNKPSC 581
Score = 33.9 bits (76), Expect = 0.30
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 157 FCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDP 216
F KK P P + + G + + C+ GY L G+ C +S S +Q+
Sbjct: 2254 FQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLS-SQLQFEGS 2312
Query: 217 LPECREIYCPA 227
LP C E CPA
Sbjct: 2313 LPTC-EAQCPA 2322
Score = 32.7 bits (73), Expect = 0.67
Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 18/139 (12%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECR 221
SC +PG NG G +T++FSC+ GY L + L+ + QW+ LP C
Sbjct: 873 SCLDPGIPVNGHRH-GGDFGIRSTVTFSCDPGYTL---SDDEPLVCERNHQWNHALPSC- 927
Query: 222 EIYCPAPPQIDNGII--QGERDHYGYRQSVTYAC----NKGFTMIGEHSIYCTVNND--- 272
+ C Q +G + G D Y + T+ KG MI H+ + ++D
Sbjct: 928 DALCGGYIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMI-FHTFHLESSHDYLL 986
Query: 273 ---EGEWSGPPPECRGKSL 288
+G +S P G L
Sbjct: 987 ITEDGSFSEPVARLTGSVL 1005
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 9/87 (10%)
Query: 34 GDCGLPPDVPNAQPALEGRT--SFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIE 91
G CG P PA RT SF +T++C +F ++ GE+ + C + +QWS +
Sbjct: 526 GGCGDP-----GIPAYGKRTGSSFLHGDTLTFECPAAF-ELVGER-VITCQQNNQWSGNK 578
Query: 92 EFCNRSCEVPTRLNSASLKQPYITQNY 118
C SC +S + P + Y
Sbjct: 579 PSCVFSCFFNFTASSGIILSPNYPEEY 605
Score = 32.0 bits (71), Expect = 1.1
Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Query: 148 NLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLIS 207
++++ST++ +C +PG +NG G T++F C+ GY+L G C+
Sbjct: 1381 SIQFSTSIA----ATCNDPGMPQNGT-RYGDSREAGDTVTFQCDPGYQLQGQAKITCVQL 1435
Query: 208 GSSVQWSDPLPEC 220
+ W P C
Sbjct: 1436 NNRFFWQPDPPTC 1448
Score = 31.6 bits (70), Expect = 1.5
Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 242 HYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
H+G S+T++C G+ + G + C + WS P P C
Sbjct: 1061 HFGVGDSLTFSCFLGYRLEGATKLTC-LGGGRRVWSAPLPRC 1101
Score = 30.8 bits (68), Expect = 2.6
Identities = 48/238 (20%), Positives = 84/238 (35%), Gaps = 24/238 (10%)
Query: 53 TSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ----WSDIEEFCNRSCEVPTRLNSAS 108
T F + ITY+C+ + + + S+ C+ G+ W + CN C +
Sbjct: 1579 TDFKLGSTITYQCDSGYKIL--DPSSITCVIGADGKPSWDQVLPSCNAPCGGQYTGSEGV 1636
Query: 109 LKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCL--QNLKWSTAVEFCKKKSCPNP 166
+ P NY G + Y PK + Q + TA+ +
Sbjct: 1637 VLSPNYPHNY-TAGQICLYSITV---------PKEFVVFGQFAYFQTALNDLAELFDGTH 1686
Query: 167 GEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCP 226
+ R + G G T+ + + L S S G + +P + C
Sbjct: 1687 AQAR--LLSSLSGSHSGETLPLATSNQILLRFSAKSGASARGFHFVYQ-AVPRTSDTQCS 1743
Query: 227 APPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYC-TVNNDEGEWSGPPPEC 283
+ P+ G G G V + CN G+ + G +++C +V N +W+ P C
Sbjct: 1744 SVPEPRYGRRIGSEFSAG--SIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC 1799
Score = 30.8 bits (68), Expect = 2.6
Identities = 51/247 (20%), Positives = 83/247 (33%), Gaps = 63/247 (25%)
Query: 96 RSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTC--LQNLKWST 153
+ C+ P + A + + F +G V+Y+C PGY + LTC L++
Sbjct: 2257 KKCQPPPAVPQAEM---LTEDDDFEIGDFVKYQCHPGYTLVG--TDILTCKLSSQLQFEG 2311
Query: 154 AVEFCKKKSCPNPGEIRNGQIDV------PGGILFGATISFSC----NTGYKLF------ 197
++ C+ + CP E+R G V PG T S+S N +F
Sbjct: 2312 SLPTCEAQ-CP-ANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQS 2369
Query: 198 --------------GSTSSFCLISGSSVQWSDPLPECREI-------------------- 223
G + ++SG+ + S+ ++
Sbjct: 2370 EKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYA 2429
Query: 224 --YCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNN-DEGEWSGPP 280
YC + NG I R V Y C G+ M+G + C N +W
Sbjct: 2430 APYCSLTHPLKNGGIL-NRTAGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLT 2488
Query: 281 PECRGKS 287
P C+ S
Sbjct: 2489 PLCQAVS 2495
Score = 30.4 bits (67), Expect = 3.3
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
Query: 232 DNGI-IQGER--DHYGYRQSVTYACNKGFTMI-GEHSIYCTVNNDEGEWSGPPPEC 283
D GI I G R D + SV++ C+ GF G SI C + + WS P C
Sbjct: 700 DPGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRC 755
Score = 30.0 bits (66), Expect = 4.4
Identities = 16/59 (27%), Positives = 27/59 (45%), Gaps = 2/59 (3%)
Query: 162 SCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPEC 220
+C P + + I + + +SF C GY L G + C+ G+ +W+ P P C
Sbjct: 1915 ACQEPA-LPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCM-PGTVRRWNYPSPLC 1971
Score = 29.6 bits (65), Expect = 5.7
Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 119 FPVGTVVEYECRPGYRREPSLSPKLTCLQN--LKWSTAVEFCKKKSCPNPGEIRNGQIDV 176
F G++V +EC PGY + S + + N +W+ + C C R G I
Sbjct: 1758 FSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTIPSC-VVPCSGNFTQRRGTILS 1816
Query: 177 PG 178
PG
Sbjct: 1817 PG 1818
Score = 28.9 bits (63), Expect = 9.7
Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 3/59 (5%)
Query: 225 CPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
C P N I G+R Y +++ C G+T+ G I C + W+ P P C
Sbjct: 1916 CQEPALPSNSIKIGDR--YMVNDVLSFQCEPGYTLQGRSHISC-MPGTVRRWNYPSPLC 1971
>gi|27502421 CD46 antigen, complement regulatory protein isoform 13
precursor [Homo sapiens]
Length = 373
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 79.0 bits (193), Expect = 8e-15
Identities = 74/307 (24%), Positives = 122/307 (39%), Gaps = 29/307 (9%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKV---------PPTVQK 298
+V + C+KGF + G +I C N+ W P P+C S +S P K
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKCLKVSTSSTTKSPASSASGPRPTYK 307
Query: 299 PTTVNVP 305
P N P
Sbjct: 308 PPVSNYP 314
>gi|27502419 CD46 antigen, complement regulatory protein isoform 11
precursor [Homo sapiens]
Length = 348
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 77.0 bits (188), Expect = 3e-14
Identities = 67/276 (24%), Positives = 114/276 (41%), Gaps = 20/276 (7%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
+V + C+KGF + G +I C N+ W P P+C
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKC 283
>gi|27502417 CD46 antigen, complement regulatory protein isoform 10
precursor [Homo sapiens]
Length = 370
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 77.8 bits (190), Expect = 2e-14
Identities = 69/283 (24%), Positives = 117/283 (41%), Gaps = 20/283 (7%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTS 290
+V + C+KGF + G +I C N+ W P P+C S +S
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKCLKVSTSS 290
>gi|27502415 CD46 antigen, complement regulatory protein isoform 9
precursor [Homo sapiens]
Length = 363
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 77.8 bits (190), Expect = 2e-14
Identities = 69/283 (24%), Positives = 117/283 (41%), Gaps = 20/283 (7%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTS 290
+V + C+KGF + G +I C N+ W P P+C S +S
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKCLKVSTSS 290
>gi|27502413 CD46 antigen, complement regulatory protein isoform 7
precursor [Homo sapiens]
Length = 378
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 82.4 bits (202), Expect = 7e-16
Identities = 74/319 (23%), Positives = 130/319 (40%), Gaps = 25/319 (7%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT 307
+V + C+KGF + G +I C N+ W P P+C +PP+ KP ++ +
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKC-----LKVLPPSSTKPPALSHSVS 302
Query: 308 EVSPTSQKTTTKTTTPNAQ 326
S T ++ + P +
Sbjct: 303 TSSTTKSPASSASGYPKPE 321
>gi|27502411 CD46 antigen, complement regulatory protein isoform 6
precursor [Homo sapiens]
Length = 369
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 79.7 bits (195), Expect = 5e-15
Identities = 73/298 (24%), Positives = 120/298 (40%), Gaps = 26/298 (8%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
+V + C+KGF + G +I C N+ W P P+C K P KP N P
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKC------LKGPRPTYKPPVSNYP 299
>gi|27502409 CD46 antigen, complement regulatory protein isoform 5
precursor [Homo sapiens]
Length = 362
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 79.7 bits (195), Expect = 5e-15
Identities = 73/298 (24%), Positives = 120/298 (40%), Gaps = 26/298 (8%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
+V + C+KGF + G +I C N+ W P P+C K P KP N P
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKC------LKGPRPTYKPPVSNYP 299
>gi|27502407 CD46 antigen, complement regulatory protein isoform 3
precursor [Homo sapiens]
Length = 377
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 79.0 bits (193), Expect = 8e-15
Identities = 74/307 (24%), Positives = 122/307 (39%), Gaps = 29/307 (9%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKV---------PPTVQK 298
+V + C+KGF + G +I C N+ W P P+C S +S P K
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKCLKVSTSSTTKSPASSASGPRPTYK 307
Query: 299 PTTVNVP 305
P N P
Sbjct: 308 PPVSNYP 314
>gi|27502405 CD46 antigen, complement regulatory protein isoform 14
precursor [Homo sapiens]
Length = 349
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 79.7 bits (195), Expect = 5e-15
Identities = 73/298 (24%), Positives = 120/298 (40%), Gaps = 26/298 (8%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVP 305
+V + C+KGF + G +I C N+ W P P+C K P KP N P
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKC------LKGPRPTYKPPVSNYP 299
>gi|27502402 CD46 antigen, complement regulatory protein isoform 1
precursor [Homo sapiens]
Length = 392
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 84.7 bits (208), Expect = 1e-16
Identities = 81/330 (24%), Positives = 135/330 (40%), Gaps = 34/330 (10%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT 307
+V + C+KGF + G +I C N+ W P P+C +PP+ KP ++
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKC-----LKVLPPSSTKPPALS---- 298
Query: 308 EVSPTSQKTTTKTTTPNAQATRST---PVS 334
S +TTK+ +A R T PVS
Sbjct: 299 --HSVSTSSTTKSPASSASGPRPTYKPPVS 326
>gi|24432108 CD46 antigen, complement regulatory protein isoform 4
precursor [Homo sapiens]
Length = 384
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 79.0 bits (193), Expect = 8e-15
Identities = 74/307 (24%), Positives = 122/307 (39%), Gaps = 29/307 (9%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKV---------PPTVQK 298
+V + C+KGF + G +I C N+ W P P+C S +S P K
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKCLKVSTSSTTKSPASSASGPRPTYK 307
Query: 299 PTTVNVP 305
P N P
Sbjct: 308 PPVSNYP 314
>gi|27502427 CD46 antigen, complement regulatory protein isoform 12
precursor [Homo sapiens]
Length = 355
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 77.0 bits (188), Expect = 3e-14
Identities = 67/276 (24%), Positives = 114/276 (41%), Gaps = 20/276 (7%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPEC 283
+V + C+KGF + G +I C N+ W P P+C
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKC 283
>gi|27502425 CD46 antigen, complement regulatory protein isoform 8
precursor [Homo sapiens]
Length = 385
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 82.4 bits (202), Expect = 7e-16
Identities = 74/319 (23%), Positives = 130/319 (40%), Gaps = 25/319 (7%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT 307
+V + C+KGF + G +I C N+ W P P+C +PP+ KP ++ +
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKC-----LKVLPPSSTKPPALSHSVS 302
Query: 308 EVSPTSQKTTTKTTTPNAQ 326
S T ++ + P +
Sbjct: 303 TSSTTKSPASSASGYPKPE 321
>gi|27502423 CD46 antigen, complement regulatory protein isoform 2
precursor [Homo sapiens]
Length = 399
Score = 107 bits (266), Expect = 3e-23
Identities = 64/196 (32%), Positives = 96/196 (48%), Gaps = 13/196 (6%)
Query: 97 SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKW-STAV 155
+CE P + L + Y+ +G V+Y+C+ GY P L+ C +N W +
Sbjct: 34 ACEEPPTFEAMELIGK--PKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSD 91
Query: 156 EFCKKKSCPNPGEIRNGQ-IDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWS 214
+ C +++CP + NGQ + G FG + F CN GY L G +C + GS WS
Sbjct: 92 DACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWS 151
Query: 215 DPLPECREIYCPAPPQIDNG-IIQGERDHYGYRQSVTYACNKG-----FTMIGEHSIYCT 268
P C ++ C PP+I NG E + + Y +VTY+C+ F++IGE +IYC
Sbjct: 152 GKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYC- 210
Query: 269 VNNDEGEWSGPPPECR 284
D WS PEC+
Sbjct: 211 --GDNSVWSRAAPECK 224
Score = 84.7 bits (208), Expect = 1e-16
Identities = 81/330 (24%), Positives = 135/330 (40%), Gaps = 34/330 (10%)
Query: 19 PRLLLLVLLCLPAVWGD-CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKD 77
P LLL ++ L + D C PP + + + + + YKC++ + IP
Sbjct: 17 PGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLAT 76
Query: 78 SVICLKGSQWSDI-EEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRR- 135
IC + W + ++ C R E + Q + G + + C GY
Sbjct: 77 HTICDRNHTWLPVSDDACYR--ETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLI 134
Query: 136 -EPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGA--TISFSCNT 192
E L +L + WS C+K C P +I+NG+ +F +++SC+
Sbjct: 135 GEEILYCELKGSVAI-WSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDP 193
Query: 193 G-----YKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQ 247
+ L G ++ +C G + WS PEC+ + C P + I G + Y+
Sbjct: 194 APGPDPFSLIGESTIYC---GDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKA 250
Query: 248 SVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTT 307
+V + C+KGF + G +I C N+ W P P+C +PP+ KP ++
Sbjct: 251 TVMFECDKGFYLDGSDTIVCDSNS---TWDPPVPKC-----LKVLPPSSTKPPALS---- 298
Query: 308 EVSPTSQKTTTKTTTPNAQATRST---PVS 334
S +TTK+ +A R T PVS
Sbjct: 299 --HSVSTSSTTKSPASSASGPRPTYKPPVS 326
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4
[Homo sapiens]
Length = 809
Score = 97.1 bits (240), Expect = 3e-20
Identities = 60/168 (35%), Positives = 85/168 (50%), Gaps = 8/168 (4%)
Query: 122 GTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKK-KSCPNPGEIRNGQIDVP-GG 179
GTV+ Y+C PGY E S LTC +L WS A C+K +C +PGEI NG G
Sbjct: 551 GTVLTYQCEPGY--ELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAG 608
Query: 180 ILFGATISFSCNTGYKLFGSTSSFCLISGSSV-QWSDPLPECREIY--CPAPPQIDNGII 236
G+ + + C GY L G+ C + +WSD +P+C Y C P +NG
Sbjct: 609 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 668
Query: 237 QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
+ HY +S+ + C +GF +IGE +I C V +W+ PP C+
Sbjct: 669 TLYKHHYQAGESLRFFCYEGFELIGEVTITC-VPGHPSQWTSQPPLCK 715
Score = 67.0 bits (162), Expect = 3e-11
Identities = 53/175 (30%), Positives = 75/175 (42%), Gaps = 17/175 (9%)
Query: 59 TVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR--SCEVPTRLNSASLKQPYITQ 116
TV+TY+CE + + D + C WS C + +C P + + +
Sbjct: 552 TVLTYQCEPGYELLGS--DILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTA---SD 606
Query: 117 NYFPVGTVVEYECRPGYRREPSLSPKLTCLQ----NLKWSTAVEFC--KKKSCPNPGEIR 170
FPVG+ V+Y C PGY E + LTC KWS V C K + C NPG
Sbjct: 607 AGFPVGSHVQYRCLPGYSLEG--AAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 664
Query: 171 NG-QIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIY 224
NG Q G ++ F C G++L G + C + G QW+ P C+ Y
Sbjct: 665 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC-VPGHPSQWTSQPPLCKVAY 718
Score = 48.5 bits (114), Expect = 1e-05
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 7/109 (6%)
Query: 178 GGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIY-CPAPPQIDNGII 236
G ++ G +++ C GY+L GS C + WS P C++I C P +I NG
Sbjct: 546 GDLIRGTVLTYQCEPGYELLGSDILTC---QWDLSWSAAPPACQKIMTCADPGEIANGHR 602
Query: 237 QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG--EWSGPPPEC 283
+ V Y C G+++ G + C + D G +WS P+C
Sbjct: 603 TASDAGFPVGSHVQYRCLPGYSLEGAAMLTC-YSRDTGTPKWSDRVPKC 650
Score = 36.2 bits (82), Expect = 0.061
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 10/63 (15%)
Query: 162 SCPNPGEIRNGQIDV----PGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
SC P +G + V PGG T +F C++GY+L G + CL +G+ W+
Sbjct: 175 SCGFPPRPAHGDVSVTDLHPGG-----TATFHCDSGYQLQGEETLICL-NGTRPSWNGET 228
Query: 218 PEC 220
P C
Sbjct: 229 PSC 231
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3
[Homo sapiens]
Length = 840
Score = 97.1 bits (240), Expect = 3e-20
Identities = 60/168 (35%), Positives = 85/168 (50%), Gaps = 8/168 (4%)
Query: 122 GTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKK-KSCPNPGEIRNGQIDVP-GG 179
GTV+ Y+C PGY E S LTC +L WS A C+K +C +PGEI NG G
Sbjct: 595 GTVLTYQCEPGY--ELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAG 652
Query: 180 ILFGATISFSCNTGYKLFGSTSSFCLISGSSV-QWSDPLPECREIY--CPAPPQIDNGII 236
G+ + + C GY L G+ C + +WSD +P+C Y C P +NG
Sbjct: 653 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 712
Query: 237 QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
+ HY +S+ + C +GF +IGE +I C V +W+ PP C+
Sbjct: 713 TLYKHHYQAGESLRFFCYEGFELIGEVTITC-VPGHPSQWTSQPPLCK 759
Score = 65.9 bits (159), Expect = 7e-11
Identities = 55/186 (29%), Positives = 79/186 (42%), Gaps = 18/186 (9%)
Query: 59 TVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR--SCEVPTRLNSASLKQPYITQ 116
TV+TY+CE + + D + C WS C + +C P + + +
Sbjct: 596 TVLTYQCEPGYELLGS--DILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTA---SD 650
Query: 117 NYFPVGTVVEYECRPGYRREPSLSPKLTCLQ----NLKWSTAVEFC--KKKSCPNPGEIR 170
FPVG+ V+Y C PGY E + LTC KWS V C K + C NPG
Sbjct: 651 AGFPVGSHVQYRCLPGYSLEG--AAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 708
Query: 171 NG-QIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPP 229
NG Q G ++ F C G++L G + C + G QW+ P C+ P
Sbjct: 709 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC-VPGHPSQWTSQPPLCKVTQTTDPS 767
Query: 230 -QIDNG 234
Q++ G
Sbjct: 768 RQLEGG 773
Score = 48.5 bits (114), Expect = 1e-05
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 7/109 (6%)
Query: 178 GGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIY-CPAPPQIDNGII 236
G ++ G +++ C GY+L GS C + WS P C++I C P +I NG
Sbjct: 590 GDLIRGTVLTYQCEPGYELLGSDILTC---QWDLSWSAAPPACQKIMTCADPGEIANGHR 646
Query: 237 QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG--EWSGPPPEC 283
+ V Y C G+++ G + C + D G +WS P+C
Sbjct: 647 TASDAGFPVGSHVQYRCLPGYSLEGAAMLTC-YSRDTGTPKWSDRVPKC 694
Score = 36.2 bits (82), Expect = 0.061
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 10/63 (15%)
Query: 162 SCPNPGEIRNGQIDV----PGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
SC P +G + V PGG T +F C++GY+L G + CL +G+ W+
Sbjct: 219 SCGFPPRPAHGDVSVTDLHPGG-----TATFHCDSGYQLQGEETLICL-NGTRPSWNGET 272
Query: 218 PEC 220
P C
Sbjct: 273 PSC 275
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2
[Homo sapiens]
Length = 910
Score = 97.1 bits (240), Expect = 3e-20
Identities = 60/168 (35%), Positives = 85/168 (50%), Gaps = 8/168 (4%)
Query: 122 GTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKK-KSCPNPGEIRNGQIDVP-GG 179
GTV+ Y+C PGY E S LTC +L WS A C+K +C +PGEI NG G
Sbjct: 665 GTVLTYQCEPGY--ELLGSDILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAG 722
Query: 180 ILFGATISFSCNTGYKLFGSTSSFCLISGSSV-QWSDPLPECREIY--CPAPPQIDNGII 236
G+ + + C GY L G+ C + +WSD +P+C Y C P +NG
Sbjct: 723 FPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPENGYQ 782
Query: 237 QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
+ HY +S+ + C +GF +IGE +I C V +W+ PP C+
Sbjct: 783 TLYKHHYQAGESLRFFCYEGFELIGEVTITC-VPGHPSQWTSQPPLCK 829
Score = 65.9 bits (159), Expect = 7e-11
Identities = 55/186 (29%), Positives = 79/186 (42%), Gaps = 18/186 (9%)
Query: 59 TVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNR--SCEVPTRLNSASLKQPYITQ 116
TV+TY+CE + + D + C WS C + +C P + + +
Sbjct: 666 TVLTYQCEPGYELLGS--DILTCQWDLSWSAAPPACQKIMTCADPGEIANGHRTA---SD 720
Query: 117 NYFPVGTVVEYECRPGYRREPSLSPKLTCLQ----NLKWSTAVEFC--KKKSCPNPGEIR 170
FPVG+ V+Y C PGY E + LTC KWS V C K + C NPG
Sbjct: 721 AGFPVGSHVQYRCLPGYSLEG--AAMLTCYSRDTGTPKWSDRVPKCALKYEPCLNPGVPE 778
Query: 171 NG-QIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPP 229
NG Q G ++ F C G++L G + C + G QW+ P C+ P
Sbjct: 779 NGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITC-VPGHPSQWTSQPPLCKVTQTTDPS 837
Query: 230 -QIDNG 234
Q++ G
Sbjct: 838 RQLEGG 843
Score = 48.5 bits (114), Expect = 1e-05
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 7/109 (6%)
Query: 178 GGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIY-CPAPPQIDNGII 236
G ++ G +++ C GY+L GS C + WS P C++I C P +I NG
Sbjct: 660 GDLIRGTVLTYQCEPGYELLGSDILTC---QWDLSWSAAPPACQKIMTCADPGEIANGHR 716
Query: 237 QGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEG--EWSGPPPEC 283
+ V Y C G+++ G + C + D G +WS P+C
Sbjct: 717 TASDAGFPVGSHVQYRCLPGYSLEGAAMLTC-YSRDTGTPKWSDRVPKC 764
Score = 36.2 bits (82), Expect = 0.061
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 10/63 (15%)
Query: 162 SCPNPGEIRNGQIDV----PGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPL 217
SC P +G + V PGG T +F C++GY+L G + CL +G+ W+
Sbjct: 289 SCGFPPRPAHGDVSVTDLHPGG-----TATFHCDSGYQLQGEETLICL-NGTRPSWNGET 342
Query: 218 PEC 220
P C
Sbjct: 343 PSC 345
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,976,071
Number of Sequences: 37866
Number of extensions: 1113347
Number of successful extensions: 9971
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 149
Number of HSP's successfully gapped in prelim test: 147
Number of HSP's that attempted gapping in prelim test: 4202
Number of HSP's gapped (non-prelim): 2964
length of query: 440
length of database: 18,247,518
effective HSP length: 105
effective length of query: 335
effective length of database: 14,271,588
effective search space: 4780981980
effective search space used: 4780981980
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.