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Search of human proteins with 11068137
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11068137 hydroxyacid oxidase 1 [Homo sapiens]
(370 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11068137 hydroxyacid oxidase 1 [Homo sapiens] 730 0.0
gi|54234014 hydroxyacid oxidase 2 [Homo sapiens] 336 2e-92
gi|7705393 hydroxyacid oxidase 2 [Homo sapiens] 336 2e-92
gi|45006951 dihydroorotate dehydrogenase precursor [Homo sapiens] 32 0.91
gi|66933016 inosine monophosphate dehydrogenase 2 [Homo sapiens] 32 1.2
gi|156616279 inosine monophosphate dehydrogenase 1 isoform c [Ho... 31 1.6
gi|34328928 inosine monophosphate dehydrogenase 1 isoform b [Hom... 31 1.6
gi|34328930 inosine monophosphate dehydrogenase 1 isoform a [Hom... 31 1.6
gi|217035152 inosine monophosphate dehydrogenase 1 isoform d [Ho... 31 1.6
gi|217035150 inosine monophosphate dehydrogenase 1 isoform g [Ho... 31 1.6
gi|217035148 inosine monophosphate dehydrogenase 1 isoform f [Ho... 31 1.6
gi|217035146 inosine monophosphate dehydrogenase 1 isoform e [Ho... 31 1.6
gi|62955803 nucleoporin 188kDa [Homo sapiens] 31 1.6
gi|17865805 solute carrier family 8 (sodium/calcium exchanger), ... 29 5.9
gi|33946308 solute carrier family 8 (sodium/calcium exchanger), ... 29 5.9
gi|33946304 solute carrier family 8 (sodium/calcium exchanger), ... 29 5.9
gi|194354001 solute carrier family 8 (sodium/calcium exchanger),... 29 5.9
gi|15147254 solute carrier family 8 (sodium/calcium exchanger), ... 29 5.9
gi|33946311 solute carrier family 8 (sodium/calcium exchanger), ... 29 5.9
gi|31652264 RNA binding motif protein 26 [Homo sapiens] 29 7.7
>gi|11068137 hydroxyacid oxidase 1 [Homo sapiens]
Length = 370
Score = 730 bits (1884), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET 60
MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET
Sbjct: 1 MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAET 60
Query: 61 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE 120
DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE
Sbjct: 61 DLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAE 120
Query: 121 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ 180
AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ
Sbjct: 121 AGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQ 180
Query: 181 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR 240
LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR
Sbjct: 181 LRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILR 240
Query: 241 GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV 300
GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV
Sbjct: 241 GDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDV 300
Query: 301 LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360
LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV
Sbjct: 301 LKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLV 360
Query: 361 RKNPLAVSKI 370
RKNPLAVSKI
Sbjct: 361 RKNPLAVSKI 370
>gi|54234014 hydroxyacid oxidase 2 [Homo sapiens]
Length = 351
Score = 336 bits (862), Expect = 2e-92
Identities = 166/357 (46%), Positives = 241/357 (67%), Gaps = 12/357 (3%)
Query: 5 LICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLST 64
L+C+ D++ HA+ L KS D+ GA+D T DNIAAF R +L PR LR+V+E D T
Sbjct: 3 LVCLTDFQAHAREQLSKSTRDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEVDTRT 62
Query: 65 SVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPE 124
++ G+ +S PIC+ T + DGE++T RA Q+ G + S++A+ S+E++ A PE
Sbjct: 63 TIQGEEISAPICIAPTGFHCLVWPDGEMSTARAAQAAGICYITSTFASCSLEDIVIAAPE 122
Query: 125 ALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMK 184
LRW QLY++ D ++ K+L+++ E +G+KA+ +T+DTP GNR D+RN+ + +
Sbjct: 123 GLRWFQLYVHPDLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRNQLR-------R 175
Query: 185 NFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDA 244
N + L SP++ + + + I S+ W D+ W + +T LPI+ KGIL +DA
Sbjct: 176 NLTLTDLQ-SPKKG----NAIPYFQMTPISTSLCWNDLSWFQSITRLPIILKGILTKEDA 230
Query: 245 REAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKAL 304
AVKH + GI+VSNHG RQLD V A+ID L E+V AV+GK+EV+LDGGVR G DVLKAL
Sbjct: 231 ELAVKHNVQGIIVSNHGGRQLDEVLASIDALTEVVAAVKGKIEVYLDGGVRTGNDVLKAL 290
Query: 305 ALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVR 361
ALGAK +F+GRPI+WGLA +GE GV++VL IL EF +MAL+GC++V I++ LV+
Sbjct: 291 ALGAKCIFLGRPILWGLACKGEHGVKEVLNILTNEFHTSMALTGCRSVAEINRNLVQ 347
>gi|7705393 hydroxyacid oxidase 2 [Homo sapiens]
Length = 351
Score = 336 bits (862), Expect = 2e-92
Identities = 166/357 (46%), Positives = 241/357 (67%), Gaps = 12/357 (3%)
Query: 5 LICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLST 64
L+C+ D++ HA+ L KS D+ GA+D T DNIAAF R +L PR LR+V+E D T
Sbjct: 3 LVCLTDFQAHAREQLSKSTRDFIEGGADDSITRDDNIAAFKRIRLRPRYLRDVSEVDTRT 62
Query: 65 SVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPE 124
++ G+ +S PIC+ T + DGE++T RA Q+ G + S++A+ S+E++ A PE
Sbjct: 63 TIQGEEISAPICIAPTGFHCLVWPDGEMSTARAAQAAGICYITSTFASCSLEDIVIAAPE 122
Query: 125 ALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMK 184
LRW QLY++ D ++ K+L+++ E +G+KA+ +T+DTP GNR D+RN+ + +
Sbjct: 123 GLRWFQLYVHPDLQLNKQLIQRVESLGFKALVITLDTPVCGNRRHDIRNQLR-------R 175
Query: 185 NFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDA 244
N + L SP++ + + + I S+ W D+ W + +T LPI+ KGIL +DA
Sbjct: 176 NLTLTDLQ-SPKKG----NAIPYFQMTPISTSLCWNDLSWFQSITRLPIILKGILTKEDA 230
Query: 245 REAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKAL 304
AVKH + GI+VSNHG RQLD V A+ID L E+V AV+GK+EV+LDGGVR G DVLKAL
Sbjct: 231 ELAVKHNVQGIIVSNHGGRQLDEVLASIDALTEVVAAVKGKIEVYLDGGVRTGNDVLKAL 290
Query: 305 ALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVR 361
ALGAK +F+GRPI+WGLA +GE GV++VL IL EF +MAL+GC++V I++ LV+
Sbjct: 291 ALGAKCIFLGRPILWGLACKGEHGVKEVLNILTNEFHTSMALTGCRSVAEINRNLVQ 347
>gi|45006951 dihydroorotate dehydrogenase precursor [Homo sapiens]
Length = 395
Score = 32.0 bits (71), Expect = 0.91
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Query: 251 GLNGILVSNHGARQLDGVPA---TIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALG 307
GL G L S G L G P + + E+ +G+V + GGV G D L+ + G
Sbjct: 291 GLQGALRSETGG--LSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAG 348
Query: 308 AKAVFVGRPIV-WGLAFQGEKGVQDVLEILKEE 339
A V + + WG G K +++ +LKE+
Sbjct: 349 ASLVQLYTALTFWGPPVVG-KVKRELEALLKEQ 380
>gi|66933016 inosine monophosphate dehydrogenase 2 [Homo sapiens]
Length = 514
Score = 31.6 bits (70), Expect = 1.2
Identities = 23/78 (29%), Positives = 34/78 (43%), Gaps = 8/78 (10%)
Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMA 345
V V DGG++ + KALALGA V +G + GE D + + K
Sbjct: 359 VPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKK-------- 410
Query: 346 LSGCQNVKVIDKTLVRKN 363
G ++ +DK L +N
Sbjct: 411 YRGMGSLDAMDKHLSSQN 428
>gi|156616279 inosine monophosphate dehydrogenase 1 isoform c [Homo
sapiens]
Length = 589
Score = 31.2 bits (69), Expect = 1.6
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILK 337
V + DGG++ V+KALALGA V +G + GE D + + K
Sbjct: 434 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKK 485
>gi|34328928 inosine monophosphate dehydrogenase 1 isoform b [Homo
sapiens]
Length = 563
Score = 31.2 bits (69), Expect = 1.6
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILK 337
V + DGG++ V+KALALGA V +G + GE D + + K
Sbjct: 408 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKK 459
>gi|34328930 inosine monophosphate dehydrogenase 1 isoform a [Homo
sapiens]
Length = 599
Score = 31.2 bits (69), Expect = 1.6
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILK 337
V + DGG++ V+KALALGA V +G + GE D + + K
Sbjct: 444 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKK 495
>gi|217035152 inosine monophosphate dehydrogenase 1 isoform d [Homo
sapiens]
Length = 566
Score = 31.2 bits (69), Expect = 1.6
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILK 337
V + DGG++ V+KALALGA V +G + GE D + + K
Sbjct: 411 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKK 462
>gi|217035150 inosine monophosphate dehydrogenase 1 isoform g [Homo
sapiens]
Length = 489
Score = 31.2 bits (69), Expect = 1.6
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILK 337
V + DGG++ V+KALALGA V +G + GE D + + K
Sbjct: 334 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKK 385
>gi|217035148 inosine monophosphate dehydrogenase 1 isoform f [Homo
sapiens]
Length = 509
Score = 31.2 bits (69), Expect = 1.6
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILK 337
V + DGG++ V+KALALGA V +G + GE D + + K
Sbjct: 354 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKK 405
>gi|217035146 inosine monophosphate dehydrogenase 1 isoform e [Homo
sapiens]
Length = 514
Score = 31.2 bits (69), Expect = 1.6
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 286 VEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILK 337
V + DGG++ V+KALALGA V +G + GE D + + K
Sbjct: 359 VPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKK 410
>gi|62955803 nucleoporin 188kDa [Homo sapiens]
Length = 1749
Score = 31.2 bits (69), Expect = 1.6
Identities = 28/103 (27%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
Query: 205 LAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQ 264
LA Y+ DP++ I+ L+RL ++ ++ G+DA A++ L S +
Sbjct: 855 LAKYIYHKHDPALPRLAIQLLKRLATVAPMSVYACLGNDAA-AIRDAFLTRLQSKIEDMR 913
Query: 265 LDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALG 307
+ + ++ L VE G +E+FL+ V+ G+D K +LG
Sbjct: 914 IKVM--ILEFLTVAVETQPGLIELFLNLEVKDGSDGSKEFSLG 954
>gi|17865805 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform B precursor [Homo sapiens]
Length = 924
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/36 (30%), Positives = 18/36 (50%)
Query: 75 ICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSW 110
+C+ +R H+ GEL R C+ T + +S W
Sbjct: 871 VCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 906
>gi|33946308 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform F [Homo sapiens]
Length = 284
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/36 (30%), Positives = 18/36 (50%)
Query: 75 ICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSW 110
+C+ +R H+ GEL R C+ T + +S W
Sbjct: 231 VCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 266
>gi|33946304 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform D precursor [Homo sapiens]
Length = 921
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/36 (30%), Positives = 18/36 (50%)
Query: 75 ICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSW 110
+C+ +R H+ GEL R C+ T + +S W
Sbjct: 868 VCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 903
>gi|194354001 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform G [Homo sapiens]
Length = 298
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/36 (30%), Positives = 18/36 (50%)
Query: 75 ICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSW 110
+C+ +R H+ GEL R C+ T + +S W
Sbjct: 245 VCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 280
>gi|15147254 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform A precursor [Homo sapiens]
Length = 925
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/36 (30%), Positives = 18/36 (50%)
Query: 75 ICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSW 110
+C+ +R H+ GEL R C+ T + +S W
Sbjct: 872 VCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 907
>gi|33946311 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform C precursor [Homo sapiens]
Length = 927
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/36 (30%), Positives = 18/36 (50%)
Query: 75 ICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSW 110
+C+ +R H+ GEL R C+ T + +S W
Sbjct: 874 VCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 909
>gi|31652264 RNA binding motif protein 26 [Homo sapiens]
Length = 980
Score = 28.9 bits (63), Expect = 7.7
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 107 LSSWATSSIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGN 166
L SW + ++E + +A P AL L + K + K+L +A + +F+ +T
Sbjct: 13 LKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKEL--KALCIDQLDVFLQKETQIFVE 70
Query: 167 RL-DDVRNRFKLPP 179
+L D V + LPP
Sbjct: 71 KLFDAVNTKSYLPP 84
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,732,164
Number of Sequences: 37866
Number of extensions: 512040
Number of successful extensions: 1139
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1119
Number of HSP's gapped (non-prelim): 20
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.