Guide to the Human Genome
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Search of human proteins with 110611243

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110611243 neurotensin receptor 1 [Homo sapiens]
         (418 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110611243 neurotensin receptor 1 [Homo sapiens]                    836   0.0  
gi|6912538 neurotensin receptor 2 [Homo sapiens]                      295   7e-80
gi|188497623 neuromedin U receptor 1 [Homo sapiens]                   179   3e-45
gi|4504095 motilin receptor [Homo sapiens]                            177   1e-44
gi|4504097 G protein-coupled receptor 39 [Homo sapiens]               177   2e-44
gi|170932505 neuromedin U receptor 2 [Homo sapiens]                   174   1e-43
gi|38455410 growth hormone secretagogue receptor isoform 1a [Hom...   173   3e-43
gi|4758434 growth hormone secretagogue receptor isoform 1b [Homo...   127   2e-29
gi|39725940 opioid receptor, kappa 1 [Homo sapiens]                   110   2e-24
gi|149944554 somatostatin receptor 4 [Homo sapiens]                   109   4e-24
gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]      107   2e-23
gi|4503907 galanin receptor 3 [Homo sapiens]                          106   3e-23
gi|63477962 opioid receptor, delta 1 [Homo sapiens]                   102   6e-22
gi|169808392 endothelin receptor type B isoform 1 precursor [Hom...    99   7e-21
gi|4557547 endothelin receptor type B isoform 1 precursor [Homo ...    99   7e-21
gi|4885057 apelin receptor [Homo sapiens]                              97   2e-20
gi|4503383 dopamine receptor D1 [Homo sapiens]                         97   2e-20
gi|157426873 tachykinin receptor 2 [Homo sapiens]                      97   4e-20
gi|6005705 G protein-coupled receptor 182 [Homo sapiens]               96   5e-20
gi|4503905 galanin receptor 2 [Homo sapiens]                           96   6e-20
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]           95   1e-19
gi|4557859 somatostatin receptor 2 [Homo sapiens]                      95   1e-19
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec...    95   1e-19
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]       94   2e-19
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]        94   2e-19
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]      94   2e-19
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]      94   2e-19
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]      94   2e-19
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]      94   2e-19
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]       94   2e-19

>gi|110611243 neurotensin receptor 1 [Homo sapiens]
          Length = 418

 Score =  836 bits (2160), Expect = 0.0
 Identities = 418/418 (100%), Positives = 418/418 (100%)

Query: 1   MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI 60
           MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI
Sbjct: 1   MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDI 60

Query: 61  YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM 120
           YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM
Sbjct: 61  YSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAM 120

Query: 121 PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM 180
           PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM
Sbjct: 121 PVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLM 180

Query: 181 SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN 240
           SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN
Sbjct: 181 SRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVN 240

Query: 241 TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH 300
           TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH
Sbjct: 241 TFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH 300

Query: 301 GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN 360
           GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN
Sbjct: 301 GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN 360

Query: 361 PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY 418
           PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
Sbjct: 361 PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY 418


>gi|6912538 neurotensin receptor 2 [Homo sapiens]
          Length = 410

 Score =  295 bits (754), Expect = 7e-80
 Identities = 146/360 (40%), Positives = 227/360 (63%), Gaps = 31/360 (8%)

Query: 52  SELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALS 111
           + L V+T +++KVL TA+Y  ++ +G  GN ++   + + ++ ++    + +H+ SLAL+
Sbjct: 21  ARLGVDTRLWAKVLFTALYALIWALGAAGNALSVHVVLKARAGRA--GRLRHHVLSLALA 78

Query: 112 DLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAIC 171
            LL LL+ +PVELY+F+W H+PW FGD GCRGYYF+ + C YAT L+VA LS ER LA+C
Sbjct: 79  GLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAYATVLSVAGLSAERCLAVC 138

Query: 172 HPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQN--RSADGQ-HAGGLVCTPTI 228
            P +A++L++  RT+  ++  W AS  LA+PM   MG+++   +ADG+      VCT  +
Sbjct: 139 QPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKHELETADGEPEPASRVCTVLV 198

Query: 229 HTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQA-----------------A 271
               ++V IQVN  +SF+ P+ + + LN +  + L  +  Q                  +
Sbjct: 199 SRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQVPSTSTPGSSTPSRLELLS 258

Query: 272 EQGQVCTV--------GGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRR 323
           E+G +  +        GG+ S      +  R+++L+  V+VLRA+V+ +V+CWLPYH RR
Sbjct: 259 EEGLLSFIVWKKTFIQGGQVSLVRHK-DVRRIRSLQRSVQVLRAIVVMYVICWLPYHARR 317

Query: 324 LMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLC 383
           LM+CY+ D+ WT  LY+FYHYFYMVTN LFYVSS + P+LYN VS++FR +FL  ++ LC
Sbjct: 318 LMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNAVSSSFRKLFLEAVSSLC 377


>gi|188497623 neuromedin U receptor 1 [Homo sapiens]
          Length = 426

 Score =  179 bits (455), Expect = 3e-45
 Identities = 111/358 (31%), Positives = 192/358 (53%), Gaps = 28/358 (7%)

Query: 66  VTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELY 125
           + A YL +FVVG VGN +T   + R K++++     +Y+L SLA+SDLL LL+ +P+ELY
Sbjct: 63  ICATYLLIFVVGAVGNGLTCLVILRHKAMRT---PTNYYLFSLAVSDLLVLLVGLPLELY 119

Query: 126 NFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRT 185
             +W ++P+  G  GC     L +    A+ LNV +LSVERY+A+ HP +A+++++R+  
Sbjct: 120 E-MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHV 178

Query: 186 KKFISAIWLASALLAVP--MLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFM 243
           ++ + A+W  + L ++P   L  + + +    G      VC      A   +V+Q    +
Sbjct: 179 RRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALL 238

Query: 244 SFIFPMVVISVLNTIIANKL----TVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALR 299
            F  PM ++SVL  +I  +L     +++++A  +G         S ++  ++    +  R
Sbjct: 239 FFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAA----RSRYTCRLQQ-HDRGRR 293

Query: 300 HGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTI 359
              ++L  +V+ F +CW P+H  R+M+  +S  QWT  L+  + + ++++   FY+ S  
Sbjct: 294 QVTKMLFVLVVVFGICWAPFHADRVMWSVVS--QWTDGLHLAFQHVHVISGIFFYLGSAA 351

Query: 360 NPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETL 417
           NP+LY+L+S+ FR  F   L CL     R R R           S+H+LS   T  TL
Sbjct: 352 NPVLYSLMSSRFRETFQEAL-CLGACCHRLRPR----------HSSHSLSRMTTGSTL 398


>gi|4504095 motilin receptor [Homo sapiens]
          Length = 412

 Score =  177 bits (450), Expect = 1e-44
 Identities = 124/381 (32%), Positives = 186/381 (48%), Gaps = 76/381 (19%)

Query: 64  VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVE 123
           V VTAV L LFVVG  GN VT   + R + +++   T + +LGS+A+SDLL +LL +P +
Sbjct: 39  VPVTAVCLCLFVVGVSGNVVTVMLIGRYRDMRT---TTNLYLGSMAVSDLL-ILLGLPFD 94

Query: 124 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 183
           LY  +W   PW FG   CR   ++ + CTYAT L++ +LSVERYLAIC P +A+ L++R 
Sbjct: 95  LYR-LWRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRR 153

Query: 184 RTKKFISAIWLASALLAVPMLFTMGEQN-------------------------------- 211
           R +  I+ +W  + L A P LF +G +                                 
Sbjct: 154 RVRALIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRA 213

Query: 212 ---------RSADGQHAGGLVCTPT-IHTATVKVVIQVNTFMSFIFPMVVISVLNTIIAN 261
                     +A+        C P+      ++V++ V T   F  P + +S+L  +I  
Sbjct: 214 PPPSPPSGPETAEAAALFSRECRPSPAQLGALRVMLWVTT-AYFFLPFLCLSILYGLIGR 272

Query: 262 KLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHV 321
           +L    R    +G   +              GR +  R  VRVL  VV+AF++CWLP+HV
Sbjct: 273 ELWSSRRPL--RGPAAS--------------GRERGHRQTVRVLLVVVLAFIICWLPFHV 316

Query: 322 RRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLAC 381
            R+++    D +    +  F  YF +V   LFY+S++INPILYNL+S  +R       A 
Sbjct: 317 GRIIYINTEDSR----MMYFSQYFNIVALQLFYLSASINPILYNLISKKYR-------AA 365

Query: 382 LCPVWRRRRKRP-AFSRKADS 401
              +   R+ RP  F R  D+
Sbjct: 366 AFKLLLARKSRPRGFHRSRDT 386


>gi|4504097 G protein-coupled receptor 39 [Homo sapiens]
          Length = 453

 Score =  177 bits (449), Expect = 2e-44
 Identities = 112/345 (32%), Positives = 175/345 (50%), Gaps = 21/345 (6%)

Query: 53  ELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSD 112
           E +V T I  K+ +  VYL +FV+G +GN+ T       +    LQ  V  H+ SLA SD
Sbjct: 22  EFEVATWI--KITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSD 79

Query: 113 LLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICH 172
           +L  L+ MP+E Y+ IW     +     C+ + FL +AC+YAT L+V +LS ERY+AICH
Sbjct: 80  ILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICH 139

Query: 173 PFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVC--TPTIH- 229
           PF+ K +    + K  I  +W+ SAL+A+P+LF MG +    +     GL C  + T H 
Sbjct: 140 PFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHH 199

Query: 230 ----TATVKV---------VIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQV 276
               T+ + +         V Q + F +F+  +VV+  +  +  N + V+++  +++G +
Sbjct: 200 EQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMK--SQKGSL 257

Query: 277 CTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTP 336
                         E  R  A R  +  LR +V+   VCW+P  +RR+M        WT 
Sbjct: 258 AGGTRPPQLRKSESEESRT-ARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTR 316

Query: 337 FLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLAC 381
             +  Y      +   FY+SS INP+LY + S  FR +F+  L C
Sbjct: 317 SYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCC 361


>gi|170932505 neuromedin U receptor 2 [Homo sapiens]
          Length = 415

 Score =  174 bits (442), Expect = 1e-43
 Identities = 103/324 (31%), Positives = 175/324 (54%), Gaps = 25/324 (7%)

Query: 66  VTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELY 125
           V+ VY+ +FVVG +GN +    + +    Q++++  +Y+L SLA+SDLL LLL MP+E+Y
Sbjct: 48  VSVVYVPIFVVGVIGNVLVCLVILQH---QAMKTPTNYYLFSLAVSDLLVLLLGMPLEVY 104

Query: 126 NFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRT 185
             +W ++P+ FG  GC     L +   +A+ L++ ++SVERY+AI HPF+AK   +R R 
Sbjct: 105 E-MWRNYPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRA 163

Query: 186 KKFISAIWLASALLAVPMLFTMG-EQNRSADGQHA-GGLVCTPTIHTATVKVVIQVNTFM 243
            + +  +W  S L ++P     G + +   +G    G   CT          +IQV +F+
Sbjct: 164 LRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFL 223

Query: 244 SFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGV- 302
            ++ PM VISVL  ++A +L       A++G                     +  R  V 
Sbjct: 224 FYLLPMTVISVLYYLMALRLKKDKSLEADEGNA----------------NIQRPCRKSVN 267

Query: 303 RVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPI 362
           ++L  +V+ F +CW P+H+ RL F ++  E+W+  L   ++  ++V+   FY+SS +NPI
Sbjct: 268 KMLFVLVLVFAICWAPFHIDRLFFSFV--EEWSESLAAVFNLVHVVSGVFFYLSSAVNPI 325

Query: 363 LYNLVSANFRHIFLATLACLCPVW 386
           +YNL+S  F+  F   ++     W
Sbjct: 326 IYNLLSRRFQAAFQNVISSFHKQW 349


>gi|38455410 growth hormone secretagogue receptor isoform 1a [Homo
           sapiens]
          Length = 366

 Score =  173 bits (438), Expect = 3e-43
 Identities = 110/311 (35%), Positives = 168/311 (54%), Gaps = 29/311 (9%)

Query: 66  VTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELY 125
           VTA  +ALFVVG  GN +T   ++R    + L++T + +L S+A SDLL + L MP++L 
Sbjct: 46  VTATCVALFVVGIAGNLLTMLVVSR---FRELRTTTNLYLSSMAFSDLL-IFLCMPLDLV 101

Query: 126 NFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRT 185
             +W + PW FGD  C+ + F+ ++CTYAT L + +LSVERY AIC P +AK ++++ R 
Sbjct: 102 R-LWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRV 160

Query: 186 KKFISAIWLASALLAVPMLFTMG-EQNRSADGQHAGGLVCTPT---IHTATVKVVIQVNT 241
           K  I  IW  +   A P+   +G E     D        C PT   + +  + V++ V++
Sbjct: 161 KLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTN--ECRPTEFAVRSGLLTVMVWVSS 218

Query: 242 FMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHG 301
              F  P+  ++VL ++I  KL    R  A  G                   R Q  +  
Sbjct: 219 IF-FFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASL----------------RDQNHKQT 261

Query: 302 VRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINP 361
           V++L  VV AF++CWLP+HV R +F   S E  +  +     Y  +V+  LFY+S+ INP
Sbjct: 262 VKMLAVVVFAFILCWLPFHVGRYLFSK-SFEPGSLEIAQISQYCNLVSFVLFYLSAAINP 320

Query: 362 ILYNLVSANFR 372
           ILYN++S  +R
Sbjct: 321 ILYNIMSKKYR 331


>gi|4758434 growth hormone secretagogue receptor isoform 1b [Homo
           sapiens]
          Length = 289

 Score =  127 bits (318), Expect = 2e-29
 Identities = 74/202 (36%), Positives = 116/202 (57%), Gaps = 12/202 (5%)

Query: 66  VTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELY 125
           VTA  +ALFVVG  GN +T   ++R    + L++T + +L S+A SDLL + L MP++L 
Sbjct: 46  VTATCVALFVVGIAGNLLTMLVVSR---FRELRTTTNLYLSSMAFSDLL-IFLCMPLDLV 101

Query: 126 NFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRT 185
             +W + PW FGD  C+ + F+ ++CTYAT L + +LSVERY AIC P +AK ++++ R 
Sbjct: 102 R-LWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRV 160

Query: 186 KKFISAIWLASALLAVPMLFTMG-EQNRSADGQHAGGLVCTPT---IHTATVKVVIQVNT 241
           K  I  IW  +   A P+   +G E     D        C PT   + +  + V++ V++
Sbjct: 161 KLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTN--ECRPTEFAVRSGLLTVMVWVSS 218

Query: 242 FMSFIFPMVVISVLNTIIANKL 263
              F  P+  ++VL ++I  KL
Sbjct: 219 IF-FFLPVFCLTVLYSLIGRKL 239


>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
          Length = 380

 Score =  110 bits (275), Expect = 2e-24
 Identities = 95/374 (25%), Positives = 170/374 (45%), Gaps = 44/374 (11%)

Query: 33  PGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKK 92
           PG+     N S     A      ++  I   V++TAVY  +FVVG VGN++  F + R  
Sbjct: 31  PGWAEPDSNGSAGSEDAQLEPAHISPAI--PVIITAVYSVVFVVGLVGNSLVMFVIIR-- 86

Query: 93  SLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACT 152
               +++  + ++ +LAL+D L +   MP +  + +++ + W FGD  C+    +     
Sbjct: 87  -YTKMKTATNIYIFNLALADAL-VTTTMPFQ--STVYLMNSWPFGDVLCKIVISIDYYNM 142

Query: 153 YATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNR 212
           + +   +  +SV+RY+A+CHP KA    +  + K     IWL S+ + +  +   G + R
Sbjct: 143 FTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVR 202

Query: 213 SADGQHAGGLVCT---PTIHTATVKVVIQVNTFM-SFIFPMVVISVLNTIIANKLTVMVR 268
               +    + C+   P    +   + +++  F+ +F+ P+++I V  T++  +L     
Sbjct: 203 ----EDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLK---- 254

Query: 269 QAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCY 328
                  V  + G            + + LR   R++  VV  FVVCW P H+  L+   
Sbjct: 255 ------SVRLLSGSRE---------KDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEAL 299

Query: 329 ISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRR 388
            S    T  L  +Y        AL Y +S++NPILY  +  NF+  F       C   + 
Sbjct: 300 GSTSHSTAALSSYYFCI-----ALGYTNSSLNPILYAFLDENFKRCF----RDFCFPLKM 350

Query: 389 RRKRPAFSRKADSV 402
           R +R + SR  ++V
Sbjct: 351 RMERQSTSRVRNTV 364


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score =  109 bits (273), Expect = 4e-24
 Identities = 92/370 (24%), Positives = 156/370 (42%), Gaps = 59/370 (15%)

Query: 14  PAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLAL 73
           P+A     A A  EEA+  PG   A+G                       V +  +Y  +
Sbjct: 20  PSAANASSAPAEAEEAVAGPGDARAAG----------------------MVAIQCIYALV 57

Query: 74  FVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHP 133
            +VG VGN +  F + R      +++  + +L +LA++D L  +L++P    +    H  
Sbjct: 58  CLVGLVGNALVIFVILR---YAKMKTATNIYLLNLAVADEL-FMLSVPFVASSAALRH-- 111

Query: 134 WAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIW 193
           W FG   CR    +     + +   +  LSV+RY+A+ HP +A T    S  K     +W
Sbjct: 112 WPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVW 171

Query: 194 LASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVIS 253
           LAS L+ +P+     +   +  GQ     +  P  H A   V +     + F+ P++ I 
Sbjct: 172 LASLLVTLPIAI-FADTRPARGGQAVACNLQWP--HPAWSAVFVVYTFLLGFLLPVLAIG 228

Query: 254 VLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFV 313
           +   +I  K+  +  +A  Q                    R ++ +   R++  VV+ FV
Sbjct: 229 LCYLLIVGKMRAVALRAGWQ-------------------QRRRSEKKITRLVLMVVVVFV 269

Query: 314 VCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRH 373
           +CW+P++V +L+  +++    T            V+  L Y +S  NPILY  +S NFR 
Sbjct: 270 LCWMPFYVVQLLNLFVTSLDAT---------VNHVSLILSYANSCANPILYGFLSDNFRR 320

Query: 374 IFLATLACLC 383
            F   L   C
Sbjct: 321 FFQRVLCLRC 330


>gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]
          Length = 398

 Score =  107 bits (268), Expect = 2e-23
 Identities = 89/362 (24%), Positives = 170/362 (46%), Gaps = 28/362 (7%)

Query: 43  SERVLAAPSSELDVNTDIYSKVLVTAVYLALFV--VGTVGNTVTAFTLARKKSLQSLQST 100
           +E V     ++L     +  +  V  + L L +  +G VGN +    + R K +++    
Sbjct: 3   NETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRT---P 59

Query: 101 VHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVA 160
            + +L SLA++DL+ L+ A    + + I+    W +G  GC    +L+     A++ ++ 
Sbjct: 60  TNCYLVSLAVADLMVLVAAGLPNITDSIY--GSWVYGYVGCLCITYLQYLGINASSCSIT 117

Query: 161 SLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAG 220
           + ++ERY+AICHP KA+ L + SR KK I  +W  ++L  +   F + + N S   + A 
Sbjct: 118 AFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLL-DLNIST-YKDAI 175

Query: 221 GLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTV--MVRQAAEQGQVCT 278
            + C   I       +  ++  + ++ PM++ +VL   IA  L +  +     E  +   
Sbjct: 176 VISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWK 235

Query: 279 VGGEHSTFSMAIEPGR------VQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDE 332
               H   ++ +          V + +   ++L  VVI F + W+PY    ++  ++S  
Sbjct: 236 NDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLS-- 293

Query: 333 QWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKR 392
             +PF     ++F +      Y++S INP++YNL+S  FR    A    LC   ++  ++
Sbjct: 294 --SPFQ---ENWFLLFCRICIYLNSAINPVIYNLMSQKFR----AAFRKLCNCKQKPTEK 344

Query: 393 PA 394
           PA
Sbjct: 345 PA 346


>gi|4503907 galanin receptor 3 [Homo sapiens]
          Length = 368

 Score =  106 bits (265), Expect = 3e-23
 Identities = 86/331 (25%), Positives = 144/331 (43%), Gaps = 35/331 (10%)

Query: 64  VLVTAVYLALFVVGTVGNTVTAFTLARK--KSLQSLQSTVHYHLGSLALSDLLTLLLAMP 121
           V V  V+  +F++GTVGN +    L +    + Q   ST    + +LA++DL  +L  +P
Sbjct: 18  VAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVP 77

Query: 122 VELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMS 181
            +    I+    W FG   C+  + L     YA++  +A++SV+RYLA+ HP +++ L +
Sbjct: 78  FQAT--IYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRT 135

Query: 182 RSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNT 241
               +  +  +WL +AL + P L   G        ++    +C P    A  + +     
Sbjct: 136 PRNARAAVGLVWLLAALFSAPYLSYYGTV------RYGALELCVPAWEDARRRALDVATF 189

Query: 242 FMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHG 301
              ++ P+ V+S+        L   V  A                  A    R +A    
Sbjct: 190 AAGYLLPVAVVSLAYGRTLRFLWAAVGPA----------------GAAAAEARRRATGRA 233

Query: 302 VRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINP 361
            R + AV   + +CW P+H   L F Y     ++P  Y       + ++ L Y +S +NP
Sbjct: 234 GRAMLAVAALYALCWGPHHALILCFWY-GRFAFSPATY----ACRLASHCLAYANSCLNP 288

Query: 362 ILYNLVSANFRHIFLATLACLCPVWRRRRKR 392
           ++Y L S +FR    A    L P  RRRR R
Sbjct: 289 LVYALASRHFR----ARFRRLWPCGRRRRHR 315


>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
          Length = 372

 Score =  102 bits (254), Expect = 6e-22
 Identities = 81/344 (23%), Positives = 159/344 (46%), Gaps = 48/344 (13%)

Query: 37  NASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQS 96
           +A  NAS    A  +S L +       + +TA+Y A+  VG +GN +  F + R      
Sbjct: 29  SAGANASGPPGARSASSLAL------AIAITALYSAVCAVGLLGNVLVMFGIVR---YTK 79

Query: 97  LQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATA 156
           +++  + ++ +LAL+D L     +P +   ++     W FG+  C+    +     + + 
Sbjct: 80  MKTATNIYIFNLALADALATS-TLPFQSAKYLM--ETWPFGELLCKAVLSIDYYNMFTSI 136

Query: 157 LNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADG 216
             +  +SV+RY+A+CHP KA    + ++ K     IW+ ++ + VP++     + R    
Sbjct: 137 FTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRD--- 193

Query: 217 QHAGGLVC-----TPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAA 271
              G +VC     +P+ +  TV  +       +F+ P+++I+V   ++  +L        
Sbjct: 194 ---GAVVCMLQFPSPSWYWDTVTKICVF--LFAFVVPILIITVCYGLMLLRL-------- 240

Query: 272 EQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISD 331
                       S   ++    + ++LR   R++  VV AFVVCW P H+  +++  +  
Sbjct: 241 -----------RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDI 289

Query: 332 EQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIF 375
           ++  P +    H    +  AL Y +S++NP+LY  +  NF+  F
Sbjct: 290 DRRDPLVVAALH----LCIALGYANSSLNPVLYAFLDENFKRCF 329


>gi|169808392 endothelin receptor type B isoform 1 precursor [Homo
           sapiens]
          Length = 442

 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 86/386 (22%), Positives = 166/386 (43%), Gaps = 32/386 (8%)

Query: 36  GNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQ 95
           G+ +  +  R ++ P  +  +      K + T V   +FV+G +GN+     + + K ++
Sbjct: 74  GDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMR 133

Query: 96  SLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYAT 155
           +  + +   + SLAL DLL +++ +P+ +Y  +     W FG   C+   F++ A    T
Sbjct: 134 NGPNIL---IASLALGDLLHIVIDIPINVYKLL--AEDWPFGAEMCKLVPFIQKASVGIT 188

Query: 156 ALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSAD 215
            L++ +LS++RY A+    + K +     T   I  IW+ S +LAVP             
Sbjct: 189 VLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYK 248

Query: 216 GQHAGGLVCTPTIHTATVKVVIQVNTFMSFIF----PMVVISVLNTIIANKLTVMVRQAA 271
           G +    +  P   TA ++       +  F F    P+ + +   T++            
Sbjct: 249 GSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLM------------ 296

Query: 272 EQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRL--MFCYI 329
                C +  + S   +A+    ++  R   + +  +V+ F +CWLP H+ R+  +  Y 
Sbjct: 297 ----TCEMLRKKSGMQIALN-DHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYN 351

Query: 330 SDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRR 389
            ++     L  F      +   +  ++S INPI   LVS  F++ F + L C C  +  +
Sbjct: 352 QNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEK 411

Query: 390 R----KRPAFSRKADSVSSNHTLSSN 411
           +    K+     KA+    ++  SSN
Sbjct: 412 QSLEEKQSCLKFKANDHGYDNFRSSN 437


>gi|4557547 endothelin receptor type B isoform 1 precursor [Homo
           sapiens]
          Length = 442

 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 86/386 (22%), Positives = 166/386 (43%), Gaps = 32/386 (8%)

Query: 36  GNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQ 95
           G+ +  +  R ++ P  +  +      K + T V   +FV+G +GN+     + + K ++
Sbjct: 74  GDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMR 133

Query: 96  SLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYAT 155
           +  + +   + SLAL DLL +++ +P+ +Y  +     W FG   C+   F++ A    T
Sbjct: 134 NGPNIL---IASLALGDLLHIVIDIPINVYKLL--AEDWPFGAEMCKLVPFIQKASVGIT 188

Query: 156 ALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSAD 215
            L++ +LS++RY A+    + K +     T   I  IW+ S +LAVP             
Sbjct: 189 VLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYK 248

Query: 216 GQHAGGLVCTPTIHTATVKVVIQVNTFMSFIF----PMVVISVLNTIIANKLTVMVRQAA 271
           G +    +  P   TA ++       +  F F    P+ + +   T++            
Sbjct: 249 GSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLM------------ 296

Query: 272 EQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRL--MFCYI 329
                C +  + S   +A+    ++  R   + +  +V+ F +CWLP H+ R+  +  Y 
Sbjct: 297 ----TCEMLRKKSGMQIALN-DHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYN 351

Query: 330 SDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRR 389
            ++     L  F      +   +  ++S INPI   LVS  F++ F + L C C  +  +
Sbjct: 352 QNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEK 411

Query: 390 R----KRPAFSRKADSVSSNHTLSSN 411
           +    K+     KA+    ++  SSN
Sbjct: 412 QSLEEKQSCLKFKANDHGYDNFRSSN 437


>gi|4885057 apelin receptor [Homo sapiens]
          Length = 380

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 77/324 (23%), Positives = 142/324 (43%), Gaps = 28/324 (8%)

Query: 62  SKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMP 121
           S  L+ A+Y+ +F++GT GN +  +T+ R  S +  + +    + SLA++DL T ++ +P
Sbjct: 27  SGALIPAIYMLVFLLGTTGNGLVLWTVFR--SSREKRRSADIFIASLAVADL-TFVVTLP 83

Query: 122 VELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMS 181
           +    + +  + W FG   C+   +L     YA+   +  LS +RYLAI  P     L  
Sbjct: 84  LWA-TYTYRDYDWPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRL 142

Query: 182 RSRTKKFISAIWLASALLAVPMLF--TMGEQNRSADGQ--HAGGLVCTPTIHTATVKVVI 237
           R       + +W+ +ALLA+P++   T G+   +   Q      +V T +   A    + 
Sbjct: 143 RVSGAVATAVLWVLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLG 202

Query: 238 QVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQA 297
             +T + F+ P  ++      IA  +    R+   +G                    ++ 
Sbjct: 203 VSSTTVGFVVPFTIMLTCYFFIAQTIAGHFRKERIEG--------------------LRK 242

Query: 298 LRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSS 357
            R  + ++  +V+ F +CW+PYH+ + ++   S   W      F    +     + YV+S
Sbjct: 243 RRRLLSIIVVLVVTFALCWMPYHLVKTLYMLGSLLHWPCDFDLFLMNIFPYCTCISYVNS 302

Query: 358 TINPILYNLVSANFRHIFLATLAC 381
            +NP LY      FR    + L C
Sbjct: 303 CLNPFLYAFFDPRFRQACTSMLCC 326


>gi|4503383 dopamine receptor D1 [Homo sapiens]
          Length = 446

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 90/367 (24%), Positives = 160/367 (43%), Gaps = 33/367 (8%)

Query: 61  YSKVLVTAVYLALFVVGTV-GNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLA 119
           +S  ++TA +L+L ++ T+ GNT+    + R + L+S     ++ + SLA+SDLL  +L 
Sbjct: 20  FSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRS--KVTNFFVISLAVSDLLVAVLV 77

Query: 120 MP----VELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFK 175
           MP     E+  F      W FG   C  +      C+ A+ LN+  +SV+RY AI  PF+
Sbjct: 78  MPWKAVAEIAGF------WPFGSF-CNIWVAFDIMCSTASILNLCVISVDRYWAISSPFR 130

Query: 176 AKTLMSRSRTKKFISAIWLASALLA---VPMLFTMGEQNRSADGQHAGGLVCTPTIHTAT 232
            +  M+       IS  W  S L++   V + +   +    +DG             ++ 
Sbjct: 131 YERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSL 190

Query: 233 VKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVR------QAAEQGQVC--TVGGEHS 284
            +     ++ +SF  P+ ++ V  T I       +R      +AA   + C  T G    
Sbjct: 191 SRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKP 250

Query: 285 TFSMAIEPGRVQALRHGVRVLRAVVI---AFVVCWLPYHVRRLMFCYISDEQWTPFLYDF 341
                 E     + +   +VL+ + +    FV CWLP+ +   +  +    +  PF  D 
Sbjct: 251 VECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDS 310

Query: 342 YHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLAC--LCPVWRRRRKRPAFSRKA 399
             +   V     + +S++NPI+Y   +A+FR  F   L C  LCP      +  + +   
Sbjct: 311 NTFDVFVW--FGWANSSLNPIIY-AFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNG 367

Query: 400 DSVSSNH 406
            ++ S+H
Sbjct: 368 AAMFSSH 374


>gi|157426873 tachykinin receptor 2 [Homo sapiens]
          Length = 398

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 90/362 (24%), Positives = 157/362 (43%), Gaps = 46/362 (12%)

Query: 65  LVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVEL 124
           L    YLAL +V   GN +  + +   + ++++    +Y + +LAL+DL    +A     
Sbjct: 35  LWATAYLALVLVAVTGNAIVIWIILAHRRMRTV---TNYFIVNLALADLC---MAAFNAA 88

Query: 125 YNFIWV-HHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 183
           +NF++  H+ W FG A C           + +  ++ +++ +RY+AI HPF+ +  +S  
Sbjct: 89  FNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPR--LSAP 146

Query: 184 RTKKFISAIWLASALLAVPMLF----TMGEQNRS---ADGQHAGGLVCTPTIHTATVKVV 236
            TK  I+ IWL +  LA P  F    TM +       A  + +GG       H   + ++
Sbjct: 147 STKAVIAGIWLVALALASPQCFYSTVTMDQGATKCVVAWPEDSGGKTLL-LYHLVVIALI 205

Query: 237 IQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQ 296
                   +  P+ V+ V  ++I   L    R+A    Q       H           +Q
Sbjct: 206 --------YFLPLAVMFVAYSVIGLTLW---RRAVPGHQAHGANLRH-----------LQ 243

Query: 297 ALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVS 356
           A++  V+ +  VV+ F +CWLPYH    ++  +   Q   + + F    Y+    L   S
Sbjct: 244 AMKKFVKTMVLVVLTFAICWLPYH----LYFILGSFQEDIYCHKFIQQVYLALFWLAMSS 299

Query: 357 STINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRET 416
           +  NPI+Y  ++  FR  F     C CP W    K         + S +  ++   T+ET
Sbjct: 300 TMYNPIIYCCLNHRFRSGFRLAFRC-CP-WVTPTKEDKL-ELTPTTSLSTRVNRCHTKET 356

Query: 417 LY 418
           L+
Sbjct: 357 LF 358


>gi|6005705 G protein-coupled receptor 182 [Homo sapiens]
          Length = 404

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 82/348 (23%), Positives = 159/348 (45%), Gaps = 41/348 (11%)

Query: 63  KVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPV 122
           +V++ A+YLA+FVVG V N +      R      L   ++ ++ ++A++DL  ++L++PV
Sbjct: 53  RVVLFALYLAMFVVGLVENLLVICVNWRGSGRAGL---MNLYILNMAIADL-GIVLSLPV 108

Query: 123 ELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSR 182
            +   + + + W +G   CR  ++      Y++   +  LSV+RY+ +     +      
Sbjct: 109 WMLE-VTLDYTWLWGSFSCRFTHYFYFVNMYSSIFFLVCLSVDRYVTLTSASPSWQRYQH 167

Query: 183 SRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNT- 241
              +   + IW+ SA++ +P +  +    +  +G     L   P    +T  + + ++T 
Sbjct: 168 RVRRAMCAGIWVLSAIIPLPEVVHI----QLVEGPEPMCLFMAPFETYSTWALAVALSTT 223

Query: 242 FMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHG 301
            + F+ P  +I+V N + A +L                           +PG+ ++ RH 
Sbjct: 224 ILGFLLPFPLITVFNVLTACRLR--------------------------QPGQPKSRRHC 257

Query: 302 VRVLRAVVIAFVVCWLPYHVRRLMF-CYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN 360
           + +L A V  FV+CWLPYHV  L+   + +       L    ++FY V +    +   IN
Sbjct: 258 L-LLCAYVAVFVMCWLPYHVTLLLLTLHGTHISLHCHLVHLLYFFYDVIDCFSMLHCVIN 316

Query: 361 PILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTL 408
           PILYN +S +FR   L  +    P   + + +      + S S+ H++
Sbjct: 317 PILYNFLSPHFRGRLLNAVVHYLP---KDQTKAGTCASSSSCSTQHSI 361


>gi|4503905 galanin receptor 2 [Homo sapiens]
          Length = 387

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 88/321 (27%), Positives = 146/321 (45%), Gaps = 38/321 (11%)

Query: 64  VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVE 123
           V+V  ++  +F+VGTVGNT+    L R     S   T +  + +L ++DL  +L  +P +
Sbjct: 26  VIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVS---TTNLFILNLGVADLCFILCCVPFQ 82

Query: 124 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 183
               I+    W FG   C+  +FL     +A++  +A++S++RYLAI +P  ++ L +  
Sbjct: 83  AT--IYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPR 140

Query: 184 RTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFM 243
                I  IW  S L + P L      +     Q A   VC P   +A  +  + + TF+
Sbjct: 141 NALAAIGLIWGLSLLFSGPYL------SYYRQSQLANLTVCHPA-WSAPRRRAMDICTFV 193

Query: 244 -SFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGV 302
            S++ P++   VL    A  L  + R               +   +A   G  +A R   
Sbjct: 194 FSYLLPVL---VLGLTYARTLRYLWR---------------AVDPVAAGSGARRAKRKVT 235

Query: 303 RVLRAVVIAFVVCWLPYHVRRLMFC-YISDEQWTPFLYDFYHYFYMVTNALFYVSSTINP 361
           R++  V   F +CW+P+H   L+ C +      T   Y      ++V+    Y +S +NP
Sbjct: 236 RMILIVAALFCLCWMPHHA--LILCVWFGQFPLTRATYALRILSHLVS----YANSCVNP 289

Query: 362 ILYNLVSANFRHIFLATLACL 382
           I+Y LVS +FR  F    A L
Sbjct: 290 IVYALVSKHFRKGFRTICAGL 310


>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
          Length = 384

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 82/354 (23%), Positives = 145/354 (40%), Gaps = 48/354 (13%)

Query: 47  LAAPSSELDVNTDIYSK---VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHY 103
           +++ S++L VN D        ++ AVY  + ++G +GN          KS++++ +    
Sbjct: 21  ISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLF-- 78

Query: 104 HLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLS 163
            + SLAL DLL L+   PV+   ++     W FG  GC+   F++      +   + +LS
Sbjct: 79  -ISSLALGDLLLLITCAPVDASRYL--ADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALS 135

Query: 164 VERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLV 223
            +RY AI  P   +   +  +     + IW+ S LLA+P            +  +   + 
Sbjct: 136 ADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFIS 195

Query: 224 CTPTIHTATV--KVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGG 281
           C P  H+  +  K+    +  + ++ P+ +ISV    IA  L         +G +     
Sbjct: 196 CAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHV--- 252

Query: 282 EHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDF 341
                       ++++ +   + +   V  F  CWLP HV               +LY  
Sbjct: 253 ----------KKQIESRKRLAKTVLVFVGLFAFCWLPNHV--------------IYLYRS 288

Query: 342 YHYFYMVTNALFYV-----------SSTINPILYNLVSANFRHIFLATLACLCP 384
           YHY  + T+ L +V           +S +NP    L+S +FR  F   L C  P
Sbjct: 289 YHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQP 342


>gi|4557859 somatostatin receptor 2 [Homo sapiens]
          Length = 369

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 83/336 (24%), Positives = 151/336 (44%), Gaps = 35/336 (10%)

Query: 51  SSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLAL 110
           S++ +   D+ S  ++T +Y  + ++G  GNT+  + + R   ++++    + ++ +LA+
Sbjct: 31  SNQTEPYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTI---TNIYILNLAI 87

Query: 111 SDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAI 170
           +D L  +L +P        VH  W FG A CR    +     + +   +  +S++RYLA+
Sbjct: 88  ADEL-FMLGLPFLAMQVALVH--WPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAV 144

Query: 171 CHPFKAKTLMSRSRTKKFIS-AIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIH 229
            HP K+     R RT K I+ A+W  S L+ +P++   G   RS     +   +  P   
Sbjct: 145 VHPIKS-AKWRRPRTAKMITMAVWGVSLLVILPIMIYAG--LRSNQWGRSSCTINWPGES 201

Query: 230 TATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMA 289
            A     I     + F+ P+ +I +    I  K+         +     VG         
Sbjct: 202 GAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKV---------KSSGIRVGSSK------ 246

Query: 290 IEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVT 349
               R ++ +   R++  VV  F+ CWLP+++  +    ++    TP L   + +  ++T
Sbjct: 247 ----RKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISP-TPALKGMFDFVVVLT 301

Query: 350 NALFYVSSTINPILYNLVSANFRHIFLATLACLCPV 385
               Y +S  NPILY  +S NF+  F   L CL  V
Sbjct: 302 ----YANSCANPILYAFLSDNFKKSFQNVL-CLVKV 332


>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
           receptor [Homo sapiens]
          Length = 368

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 82/354 (23%), Positives = 145/354 (40%), Gaps = 48/354 (13%)

Query: 47  LAAPSSELDVNTDIYSK---VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHY 103
           +++ S++L VN D        ++ AVY  + ++G +GN          KS++++ +    
Sbjct: 5   ISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLF-- 62

Query: 104 HLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLS 163
            + SLAL DLL L+   PV+   ++     W FG  GC+   F++      +   + +LS
Sbjct: 63  -ISSLALGDLLLLITCAPVDASRYL--ADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALS 119

Query: 164 VERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLV 223
            +RY AI  P   +   +  +     + IW+ S LLA+P            +  +   + 
Sbjct: 120 ADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFIS 179

Query: 224 CTPTIHTATV--KVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGG 281
           C P  H+  +  K+    +  + ++ P+ +ISV    IA  L         +G +     
Sbjct: 180 CAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHV--- 236

Query: 282 EHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDF 341
                       ++++ +   + +   V  F  CWLP HV               +LY  
Sbjct: 237 ----------KKQIESRKRLAKTVLVFVGLFAFCWLPNHV--------------IYLYRS 272

Query: 342 YHYFYMVTNALFYV-----------SSTINPILYNLVSANFRHIFLATLACLCP 384
           YHY  + T+ L +V           +S +NP    L+S +FR  F   L C  P
Sbjct: 273 YHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQP 326


>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
          Length = 493

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/315 (23%), Positives = 145/315 (46%), Gaps = 39/315 (12%)

Query: 64  VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVE 123
           + + A+Y  + VVG  GN +  + + R      +++  + ++ +LAL+D L     +P +
Sbjct: 164 ITIMALYSIVCVVGLFGNFLVMYVIVR---YTKMKTATNIYIFNLALADALATS-TLPFQ 219

Query: 124 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 183
             N++     W FG   C+    +     + +   + ++SV+RY+A+CHP KA    +  
Sbjct: 220 SVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 277

Query: 184 RTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTAT--VKVVIQVNT 241
             K      W+ S+ + +P++F    + R       G + CT T    T   + ++++  
Sbjct: 278 NAKIINVCNWILSSAIGLPVMFMATTKYRQ------GSIDCTLTFSHPTWYWENLLKICV 331

Query: 242 FM-SFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH 300
           F+ +FI P+++I+V   ++  +L                    S   ++    + + LR 
Sbjct: 332 FIFAFIMPVLIITVCYGLMILRL-------------------KSVRMLSGSKEKDRNLRR 372

Query: 301 GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN 360
             R++  VV  F+VCW P H+  ++   ++  + T F    +H+      AL Y +S +N
Sbjct: 373 ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE-TTFQTVSWHFCI----ALGYTNSCLN 427

Query: 361 PILYNLVSANFRHIF 375
           P+LY  +  NF+  F
Sbjct: 428 PVLYAFLDENFKRCF 442


>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
          Length = 400

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/315 (23%), Positives = 145/315 (46%), Gaps = 39/315 (12%)

Query: 64  VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVE 123
           + + A+Y  + VVG  GN +  + + R      +++  + ++ +LAL+D L     +P +
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVR---YTKMKTATNIYIFNLALADALATS-TLPFQ 126

Query: 124 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 183
             N++     W FG   C+    +     + +   + ++SV+RY+A+CHP KA    +  
Sbjct: 127 SVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184

Query: 184 RTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTAT--VKVVIQVNT 241
             K      W+ S+ + +P++F    + R       G + CT T    T   + ++++  
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQ------GSIDCTLTFSHPTWYWENLLKICV 238

Query: 242 FM-SFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH 300
           F+ +FI P+++I+V   ++  +L                    S   ++    + + LR 
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-------------------KSVRMLSGSKEKDRNLRR 279

Query: 301 GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN 360
             R++  VV  F+VCW P H+  ++   ++  + T F    +H+      AL Y +S +N
Sbjct: 280 ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE-TTFQTVSWHFCI----ALGYTNSCLN 334

Query: 361 PILYNLVSANFRHIF 375
           P+LY  +  NF+  F
Sbjct: 335 PVLYAFLDENFKRCF 349


>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
          Length = 420

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/315 (23%), Positives = 145/315 (46%), Gaps = 39/315 (12%)

Query: 64  VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVE 123
           + + A+Y  + VVG  GN +  + + R      +++  + ++ +LAL+D L     +P +
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVR---YTKMKTATNIYIFNLALADALATS-TLPFQ 126

Query: 124 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 183
             N++     W FG   C+    +     + +   + ++SV+RY+A+CHP KA    +  
Sbjct: 127 SVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184

Query: 184 RTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTAT--VKVVIQVNT 241
             K      W+ S+ + +P++F    + R       G + CT T    T   + ++++  
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQ------GSIDCTLTFSHPTWYWENLLKICV 238

Query: 242 FM-SFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH 300
           F+ +FI P+++I+V   ++  +L                    S   ++    + + LR 
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-------------------KSVRMLSGSKEKDRNLRR 279

Query: 301 GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN 360
             R++  VV  F+VCW P H+  ++   ++  + T F    +H+      AL Y +S +N
Sbjct: 280 ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE-TTFQTVSWHFCI----ALGYTNSCLN 334

Query: 361 PILYNLVSANFRHIF 375
           P+LY  +  NF+  F
Sbjct: 335 PVLYAFLDENFKRCF 349


>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
          Length = 397

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/315 (23%), Positives = 145/315 (46%), Gaps = 39/315 (12%)

Query: 64  VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVE 123
           + + A+Y  + VVG  GN +  + + R      +++  + ++ +LAL+D L     +P +
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVR---YTKMKTATNIYIFNLALADALATS-TLPFQ 126

Query: 124 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 183
             N++     W FG   C+    +     + +   + ++SV+RY+A+CHP KA    +  
Sbjct: 127 SVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184

Query: 184 RTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTAT--VKVVIQVNT 241
             K      W+ S+ + +P++F    + R       G + CT T    T   + ++++  
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQ------GSIDCTLTFSHPTWYWENLLKICV 238

Query: 242 FM-SFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH 300
           F+ +FI P+++I+V   ++  +L                    S   ++    + + LR 
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-------------------KSVRMLSGSKEKDRNLRR 279

Query: 301 GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN 360
             R++  VV  F+VCW P H+  ++   ++  + T F    +H+      AL Y +S +N
Sbjct: 280 ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE-TTFQTVSWHFCI----ALGYTNSCLN 334

Query: 361 PILYNLVSANFRHIF 375
           P+LY  +  NF+  F
Sbjct: 335 PVLYAFLDENFKRCF 349


>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
          Length = 403

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/315 (23%), Positives = 145/315 (46%), Gaps = 39/315 (12%)

Query: 64  VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVE 123
           + + A+Y  + VVG  GN +  + + R      +++  + ++ +LAL+D L     +P +
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVR---YTKMKTATNIYIFNLALADALATS-TLPFQ 126

Query: 124 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 183
             N++     W FG   C+    +     + +   + ++SV+RY+A+CHP KA    +  
Sbjct: 127 SVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184

Query: 184 RTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTAT--VKVVIQVNT 241
             K      W+ S+ + +P++F    + R       G + CT T    T   + ++++  
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQ------GSIDCTLTFSHPTWYWENLLKICV 238

Query: 242 FM-SFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH 300
           F+ +FI P+++I+V   ++  +L                    S   ++    + + LR 
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-------------------KSVRMLSGSKEKDRNLRR 279

Query: 301 GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN 360
             R++  VV  F+VCW P H+  ++   ++  + T F    +H+      AL Y +S +N
Sbjct: 280 ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE-TTFQTVSWHFCI----ALGYTNSCLN 334

Query: 361 PILYNLVSANFRHIF 375
           P+LY  +  NF+  F
Sbjct: 335 PVLYAFLDENFKRCF 349


>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
          Length = 406

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/315 (23%), Positives = 145/315 (46%), Gaps = 39/315 (12%)

Query: 64  VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVE 123
           + + A+Y  + VVG  GN +  + + R      +++  + ++ +LAL+D L     +P +
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVR---YTKMKTATNIYIFNLALADALATS-TLPFQ 126

Query: 124 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 183
             N++     W FG   C+    +     + +   + ++SV+RY+A+CHP KA    +  
Sbjct: 127 SVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184

Query: 184 RTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTAT--VKVVIQVNT 241
             K      W+ S+ + +P++F    + R       G + CT T    T   + ++++  
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQ------GSIDCTLTFSHPTWYWENLLKICV 238

Query: 242 FM-SFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH 300
           F+ +FI P+++I+V   ++  +L                    S   ++    + + LR 
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-------------------KSVRMLSGSKEKDRNLRR 279

Query: 301 GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN 360
             R++  VV  F+VCW P H+  ++   ++  + T F    +H+      AL Y +S +N
Sbjct: 280 ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE-TTFQTVSWHFCI----ALGYTNSCLN 334

Query: 361 PILYNLVSANFRHIF 375
           P+LY  +  NF+  F
Sbjct: 335 PVLYAFLDENFKRCF 349


>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
          Length = 392

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 73/315 (23%), Positives = 145/315 (46%), Gaps = 39/315 (12%)

Query: 64  VLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVE 123
           + + A+Y  + VVG  GN +  + + R      +++  + ++ +LAL+D L     +P +
Sbjct: 71  ITIMALYSIVCVVGLFGNFLVMYVIVR---YTKMKTATNIYIFNLALADALATS-TLPFQ 126

Query: 124 LYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRS 183
             N++     W FG   C+    +     + +   + ++SV+RY+A+CHP KA    +  
Sbjct: 127 SVNYLM--GTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPR 184

Query: 184 RTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTAT--VKVVIQVNT 241
             K      W+ S+ + +P++F    + R       G + CT T    T   + ++++  
Sbjct: 185 NAKIINVCNWILSSAIGLPVMFMATTKYRQ------GSIDCTLTFSHPTWYWENLLKICV 238

Query: 242 FM-SFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRH 300
           F+ +FI P+++I+V   ++  +L                    S   ++    + + LR 
Sbjct: 239 FIFAFIMPVLIITVCYGLMILRL-------------------KSVRMLSGSKEKDRNLRR 279

Query: 301 GVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTIN 360
             R++  VV  F+VCW P H+  ++   ++  + T F    +H+      AL Y +S +N
Sbjct: 280 ITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE-TTFQTVSWHFCI----ALGYTNSCLN 334

Query: 361 PILYNLVSANFRHIF 375
           P+LY  +  NF+  F
Sbjct: 335 PVLYAFLDENFKRCF 349


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.135    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,025,779
Number of Sequences: 37866
Number of extensions: 531291
Number of successful extensions: 3658
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 440
Number of HSP's successfully gapped in prelim test: 290
Number of HSP's that attempted gapping in prelim test: 2310
Number of HSP's gapped (non-prelim): 966
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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