Guide to the Human Genome
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Search of human proteins with 165377209

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|165377209 methyltransferase 5 domain containing 1 isoform 1
[Homo sapiens]
         (407 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|165377209 methyltransferase 5 domain containing 1 isoform 1 [...   811   0.0  
gi|165377202 methyltransferase 5 domain containing 1 isoform 2 [...   524   e-149
gi|32698918 NOL1/NOP2/Sun domain family, member 6 [Homo sapiens]       35   0.16 
gi|40316918 NOL1/NOP2/Sun domain family 4 protein [Homo sapiens]       32   0.79 
gi|88702793 slit-like 2 [Homo sapiens]                                 32   0.79 
gi|66346737 glucosidase, alpha; neutral C [Homo sapiens]               31   1.8  
gi|150418005 protein tyrosine phosphatase, non-receptor type 21 ...    29   6.7  
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         29   6.7  
gi|76150625 nucleolar protein 1, 120kDa [Homo sapiens]                 29   8.7  
gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens]                 29   8.7  
gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sap...    29   8.7  
gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sap...    29   8.7  

>gi|165377209 methyltransferase 5 domain containing 1 isoform 1
           [Homo sapiens]
          Length = 407

 Score =  811 bits (2094), Expect = 0.0
 Identities = 407/407 (100%), Positives = 407/407 (100%)

Query: 1   MLRYPYFCRMYKECLSCWLESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRS 60
           MLRYPYFCRMYKECLSCWLESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRS
Sbjct: 1   MLRYPYFCRMYKECLSCWLESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRS 60

Query: 61  QDRDFETMAKLHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDR 120
           QDRDFETMAKLHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDR
Sbjct: 61  QDRDFETMAKLHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDR 120

Query: 121 DPTAYALAEHLSELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTP 180
           DPTAYALAEHLSELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTP
Sbjct: 121 DPTAYALAEHLSELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTP 180

Query: 181 ERGFSLRKDGPLDMRMDGGRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIV 240
           ERGFSLRKDGPLDMRMDGGRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIV
Sbjct: 181 ERGFSLRKDGPLDMRMDGGRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIV 240

Query: 241 QARSIYPITRTQQLASIVAGAFPPSAIYTRKDLLQRSTHIATKTFQALRIFVNNELNELY 300
           QARSIYPITRTQQLASIVAGAFPPSAIYTRKDLLQRSTHIATKTFQALRIFVNNELNELY
Sbjct: 241 QARSIYPITRTQQLASIVAGAFPPSAIYTRKDLLQRSTHIATKTFQALRIFVNNELNELY 300

Query: 301 TGLKTAQKFLRPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSVRQQVMKTSQLGSDH 360
           TGLKTAQKFLRPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSVRQQVMKTSQLGSDH
Sbjct: 301 TGLKTAQKFLRPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSVRQQVMKTSQLGSDH 360

Query: 361 ENTEEVSMRRAPLMWELIHKKVLSPQDQDVQDNPRGRSAKLRAAIKL 407
           ENTEEVSMRRAPLMWELIHKKVLSPQDQDVQDNPRGRSAKLRAAIKL
Sbjct: 361 ENTEEVSMRRAPLMWELIHKKVLSPQDQDVQDNPRGRSAKLRAAIKL 407


>gi|165377202 methyltransferase 5 domain containing 1 isoform 2
           [Homo sapiens]
          Length = 273

 Score =  524 bits (1349), Expect = e-149
 Identities = 259/259 (100%), Positives = 259/259 (100%)

Query: 1   MLRYPYFCRMYKECLSCWLESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRS 60
           MLRYPYFCRMYKECLSCWLESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRS
Sbjct: 1   MLRYPYFCRMYKECLSCWLESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRS 60

Query: 61  QDRDFETMAKLHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDR 120
           QDRDFETMAKLHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDR
Sbjct: 61  QDRDFETMAKLHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDR 120

Query: 121 DPTAYALAEHLSELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTP 180
           DPTAYALAEHLSELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTP
Sbjct: 121 DPTAYALAEHLSELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTP 180

Query: 181 ERGFSLRKDGPLDMRMDGGRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIV 240
           ERGFSLRKDGPLDMRMDGGRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIV
Sbjct: 181 ERGFSLRKDGPLDMRMDGGRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIV 240

Query: 241 QARSIYPITRTQQLASIVA 259
           QARSIYPITRTQQLASIVA
Sbjct: 241 QARSIYPITRTQQLASIVA 259


>gi|32698918 NOL1/NOP2/Sun domain family, member 6 [Homo sapiens]
          Length = 469

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 30/106 (28%), Positives = 49/106 (46%), Gaps = 12/106 (11%)

Query: 80  VVHCLSPQKGQIFLDMTFGSGG---HTKAILQKESDIVLYALDR-DPTAYALAEHLSELY 135
           V H L+PQ G+  LD+    GG   H  A++  + +++  ALD+       + ++   L 
Sbjct: 226 VSHVLNPQPGEKILDLCAAPGGKTTHIAALMHDQGEVI--ALDKIFNKVEKIKQNALLLG 283

Query: 136 PKQIRAMLGQFSQAEALLMKAGVQ------PGTFDGVLMDLGCSSM 175
              IRA     ++A  L M    +      P +FD +L+D  CS M
Sbjct: 284 LNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAPCSGM 329


>gi|40316918 NOL1/NOP2/Sun domain family 4 protein [Homo sapiens]
          Length = 384

 Score = 32.3 bits (72), Expect = 0.79
 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 3/96 (3%)

Query: 81  VHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDRDPTAYALAEHLSELY-PKQI 139
           V  L  Q G I LD+    GG T A+LQ      L A D  P+  A  + +   Y P++I
Sbjct: 166 VLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEI 225

Query: 140 RAMLGQFSQAEALLMKAGVQPG-TFDGVLMDLGCSS 174
           R    Q         K G   G T+D VL+D+ C++
Sbjct: 226 RDG-NQVRVTSWDGRKWGELEGDTYDRVLVDVPCTT 260


>gi|88702793 slit-like 2 [Homo sapiens]
          Length = 673

 Score = 32.3 bits (72), Expect = 0.79
 Identities = 40/153 (26%), Positives = 66/153 (43%), Gaps = 25/153 (16%)

Query: 253 QLASIVAGAFPPSAIYTRKDLLQRSTH-IATKTFQALRIFVNNELNELYTGLKTAQKFLR 311
           Q+AS+ +G F P A  +  DL     H I  +TF+ LR      L  LY G K   + ++
Sbjct: 87  QIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLR-----RLERLYLG-KNRIRHIQ 140

Query: 312 PGG-----RLVALSFHSLEDRIVKRF----LLGISMTERFNLSVRQQVMKTSQLGSDHEN 362
           PG      RL+ L     E R +       LL + ++    L++   ++ T+       N
Sbjct: 141 PGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTA-------N 193

Query: 363 TEEVSMRRAPL--MWELIHKKVLSPQDQDVQDN 393
            E + +    L  + E +  ++ +  D DV DN
Sbjct: 194 VEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDN 226


>gi|66346737 glucosidase, alpha; neutral C [Homo sapiens]
          Length = 914

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 18/70 (25%), Positives = 33/70 (47%)

Query: 20  ESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRSQDRDFETMAKLHIPVMVDE 79
           E  IP   +W +  HT  ++Y  ++     +  + QEL RS+ R    ++  HI +  D 
Sbjct: 387 EHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKIDPDY 446

Query: 80  VVHCLSPQKG 89
            V+  +  +G
Sbjct: 447 SVYVKAKDQG 456


>gi|150418005 protein tyrosine phosphatase, non-receptor type 21
           [Homo sapiens]
          Length = 1174

 Score = 29.3 bits (64), Expect = 6.7
 Identities = 39/150 (26%), Positives = 60/150 (40%), Gaps = 28/150 (18%)

Query: 272 DLLQRSTHIATKTFQALRIFVNNELNEL---YTGLKTAQKFLRPGGRLVALSFHSLEDRI 328
           DL+ R  H + +TFQ   + V + L E+    T  + AQ   R    +  LS H LE   
Sbjct: 593 DLITRRVHHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLS-HGLE--- 648

Query: 329 VKRFLLGISMTER-FNLSVRQQVMKTSQLGSDHENTEEVSMRRAPLMWELI---HKKVLS 384
                 G+ + ER  + S  +   +   +GS      E + R  P   E +   HKK LS
Sbjct: 649 ------GLRLKERTLSASAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLS 702

Query: 385 -----------PQDQDVQDNPRGRSAKLRA 403
                       +D+D ++    R+   RA
Sbjct: 703 DATMLIHSSEEEEDEDFEEESGARAPPARA 732


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 29.3 bits (64), Expect = 6.7
 Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 5/42 (11%)

Query: 28   VWP---NRIHTTAEKYREYEAREQTDQTQAQELHRSQDRDFE 66
            +WP   +R HTT  KY +Y+A   + Q   QE   S+D + E
Sbjct: 1265 IWPCESSRSHTTIAKYAQYQA--SSFQESLQEEKESEDEESE 1304


>gi|76150625 nucleolar protein 1, 120kDa [Homo sapiens]
          Length = 808

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 9/135 (6%)

Query: 81  VHCLSPQKGQIFLDMTFGSGGHTK--AILQKESDIVLYALDRDPTAYALAEHLSELYPKQ 138
           V  L+PQ+ +  LDM    GG T   A L K + ++   L  D  A  L   +  L+   
Sbjct: 373 VMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVI---LANDANAERLKSVVGNLHRLG 429

Query: 139 IRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTPERGFSLRKDGPLDMRMDG 198
           +   +   S  +       V  G FD VL+D  CS   + + +      KD    +R   
Sbjct: 430 VTNTI--ISHYDGRQFPKVV--GGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDILRCAH 485

Query: 199 GRYPDMPTAADVVNA 213
            +   + +A D VNA
Sbjct: 486 LQKELLLSAIDSVNA 500


>gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens]
          Length = 808

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 36/135 (26%), Positives = 55/135 (40%), Gaps = 9/135 (6%)

Query: 81  VHCLSPQKGQIFLDMTFGSGGHTK--AILQKESDIVLYALDRDPTAYALAEHLSELYPKQ 138
           V  L+PQ+ +  LDM    GG T   A L K + ++   L  D  A  L   +  L+   
Sbjct: 373 VMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGVI---LANDANAERLKSVVGNLHRLG 429

Query: 139 IRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTPERGFSLRKDGPLDMRMDG 198
           +   +   S  +       V  G FD VL+D  CS   + + +      KD    +R   
Sbjct: 430 VTNTI--ISHYDGRQFPKVV--GGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDILRCAH 485

Query: 199 GRYPDMPTAADVVNA 213
            +   + +A D VNA
Sbjct: 486 LQKELLLSAIDSVNA 500


>gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sapiens]
          Length = 1347

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 12/34 (35%), Positives = 19/34 (55%)

Query: 31   NRIHTTAEKYREYEAREQTDQTQAQELHRSQDRD 64
            NR HTT  KY +Y+A    +  + +   R+Q +D
Sbjct: 973  NRSHTTIAKYAQYQASSFQESLREENEKRTQHKD 1006


>gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sapiens]
          Length = 1240

 Score = 28.9 bits (63), Expect = 8.7
 Identities = 12/34 (35%), Positives = 19/34 (55%)

Query: 31   NRIHTTAEKYREYEAREQTDQTQAQELHRSQDRD 64
            NR HTT  KY +Y+A    +  + +   R+Q +D
Sbjct: 973  NRSHTTIAKYAQYQASSFQESLREENEKRTQHKD 1006


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,478,779
Number of Sequences: 37866
Number of extensions: 584050
Number of successful extensions: 1399
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1391
Number of HSP's gapped (non-prelim): 12
length of query: 407
length of database: 18,247,518
effective HSP length: 105
effective length of query: 302
effective length of database: 14,271,588
effective search space: 4310019576
effective search space used: 4310019576
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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