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Search of human proteins with 16306582
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|16306582 F-box and leucine-rich repeat protein 2 [Homo
sapiens]
(423 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 865 0.0
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 709 0.0
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 181 1e-45
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens] 168 7e-42
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 161 9e-40
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 161 9e-40
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens] 119 7e-27
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 100 2e-21
gi|164663798 antagonist of mitotic exit network 1 homolog [Homo ... 96 8e-20
gi|254039600 F-box and leucine-rich repeat protein 17 [Homo sapi... 93 4e-19
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 80 3e-15
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi... 79 8e-15
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 76 5e-14
gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens] 71 2e-12
gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens] 71 2e-12
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 64 3e-10
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 64 3e-10
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H... 62 1e-09
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 61 2e-09
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H... 59 8e-09
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H... 57 2e-08
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H... 57 2e-08
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 57 3e-08
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] 57 4e-08
gi|122937219 F-box protein 41 [Homo sapiens] 54 3e-07
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H... 48 2e-05
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H... 48 2e-05
gi|27312027 F-box only protein 16 [Homo sapiens] 41 0.002
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens] 40 0.004
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens] 40 0.004
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
Length = 423
Score = 865 bits (2235), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MVFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNF 60
MVFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNF
Sbjct: 1 MVFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNF 60
Query: 61 QIDVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDS 120
QIDVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDS
Sbjct: 61 QIDVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDS 120
Query: 121 TCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRG 180
TCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRG
Sbjct: 121 TCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRG 180
Query: 181 CRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALC 240
CRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALC
Sbjct: 181 CRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALC 240
Query: 241 LSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILIT 300
LSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILIT
Sbjct: 241 LSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILIT 300
Query: 301 DSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALE 360
DSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALE
Sbjct: 301 DSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALE 360
Query: 361 HLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCC 420
HLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCC
Sbjct: 361 HLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCC 420
Query: 421 VIL 423
VIL
Sbjct: 421 VIL 423
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
Length = 436
Score = 709 bits (1830), Expect = 0.0
Identities = 330/422 (78%), Positives = 377/422 (89%)
Query: 2 VFSNNDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQ 61
+FSN+DE +INKKLPKELLLRIFSFLD+VTLCRCAQ+S+AWN+LALDGSNWQRIDLF+FQ
Sbjct: 15 MFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQ 74
Query: 62 IDVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDST 121
D+EGRVVENISKRCGGFLRKLSLRGC+GVGD++L+TFAQNCRNIE LNLNGCTK TD+T
Sbjct: 75 RDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDAT 134
Query: 122 CYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGC 181
C SLS+FCSKL+HLDL SC SITN SLK +SEGC LE LN+SWCDQ+TKDGI+ALVRGC
Sbjct: 135 CTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGC 194
Query: 182 RGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCL 241
GLKAL L+GCTQLEDEALK+I +C ELV+LNLQ+C +ITDEG++ ICRGCH+LQ+LC
Sbjct: 195 GGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCA 254
Query: 242 SGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITD 301
SGCSN+TDA L ALG NCPRL+ILE ARCS LTD GFT LARNCHELEKMDLEEC+ ITD
Sbjct: 255 SGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITD 314
Query: 302 STLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEH 361
STLIQLSIHCP+LQ LSLSHCELITDDGI HL N C H++L V+ELDNC LITD +LEH
Sbjct: 315 STLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEH 374
Query: 362 LENCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCV 421
L++C LER+ELYDCQQ+TRAGIKR+R LP++KVHAYFAPVTPP +V GS QR CRCC+
Sbjct: 375 LKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCI 434
Query: 422 IL 423
IL
Sbjct: 435 IL 436
>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
Length = 491
Score = 181 bits (458), Expect = 1e-45
Identities = 109/372 (29%), Positives = 190/372 (51%), Gaps = 26/372 (6%)
Query: 14 KLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENIS 73
+LP +++IFSFL LCRCA++ + W LA D W+ I L I+V+ R ++ ++
Sbjct: 116 RLPDHSMVQIFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVD-RALKVLT 174
Query: 74 KR-CGG------FLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLS 126
+R C L +++ GC + D L T AQ C + L ++GC I++ + +
Sbjct: 175 RRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVV 234
Query: 127 RFCSKLKHLDLTSCVSITNSSL-------------KGISEGCRNLEYLNLSWCDQITKDG 173
C L+HLD++ C +T SL K IS + YL+++ C + +G
Sbjct: 235 SLCPNLEHLDVSGCSKVTCISLTREASIKLSPLHGKQIS-----IRYLDMTDCFVLEDEG 289
Query: 174 IEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGC 233
+ + C L L LR C +L DE L+++ YC + L++ C ++D G+ +I +
Sbjct: 290 LHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLE 349
Query: 234 HRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDL 293
RL+ L ++ C +TD + + C +L+ L A C +TD G LA+NC +L+ +D+
Sbjct: 350 SRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDI 409
Query: 294 EECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLL 353
+C L++D+ L L+++C L+ LSL CE IT G+ ++ + + L V + + +
Sbjct: 410 GKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVE 469
Query: 354 ITDVALEHLENC 365
H + C
Sbjct: 470 ALRFVKRHCKRC 481
>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
Length = 418
Score = 168 bits (426), Expect = 7e-42
Identities = 126/388 (32%), Positives = 190/388 (48%), Gaps = 22/388 (5%)
Query: 18 ELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENISKRCG 77
ELL IF +LD+ R AQ+ AW A S W+ ++ + ++ R
Sbjct: 11 ELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGI 70
Query: 78 GFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTC-YSLSRFCSKLKHLD 136
++ LSLR SL Q NIE LNL+GC +TD+ ++ + L+ L+
Sbjct: 71 RRVQILSLR-------RSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALN 123
Query: 137 LTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLE 196
L+ C IT+SSL I++ + LE L L C IT G+ + G + LK+L LR C L
Sbjct: 124 LSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLS 183
Query: 197 DEALKHIQNY-------CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTD 249
D + H+ C L L LQ C ++TD + I RG L+ L LS C ++D
Sbjct: 184 DVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISD 243
Query: 250 ASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSI 309
A L L + L+ L C +++D G LA L +D+ C + D +L ++
Sbjct: 244 AGLLHLS-HMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQ 302
Query: 310 HCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGL 368
L++LSL C I+DDGI + G LR L + C+ ITD LE + E+ L
Sbjct: 303 GLDGLKSLSLCSCH-ISDDGINRMVRQMHG---LRTLNIGQCVRITDKGLELIAEHLSQL 358
Query: 369 ERLELYDCQQVTRAGIKRMRAQLPHVKV 396
++LY C ++T+ G++R+ QLP +KV
Sbjct: 359 TGIDLYGCTRITKRGLERI-TQLPCLKV 385
Score = 139 bits (351), Expect = 4e-33
Identities = 89/278 (32%), Positives = 141/278 (50%), Gaps = 13/278 (4%)
Query: 78 GFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDL 137
G LR L+L C + DSSL AQ + +E L L GC+ IT++ ++ +LK L+L
Sbjct: 117 GSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNL 176
Query: 138 TSCVSITNSSL-------KGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLR 190
SC +++ + + +EGC LE L L C ++T ++ + RG GL+ L L
Sbjct: 177 RSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLS 236
Query: 191 GCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDA 250
C + D L H+ ++ L SLNL+SC I+D G++ + G RL L +S C + D
Sbjct: 237 FCGGISDAGLLHL-SHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQ 295
Query: 251 SLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIH 310
SL + L+ L C H++D G + R H L +++ +C+ ITD L ++ H
Sbjct: 296 SLAYIAQGLDGLKSLSLCSC-HISDDGINRMVRQMHGLRTLNIGQCVRITDKGLELIAEH 354
Query: 311 CPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLEL 348
+L + L C IT G+ ++ C L+VL L
Sbjct: 355 LSQLTGIDLYGCTRITKRGLERITQLPC----LKVLNL 388
>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
[Homo sapiens]
Length = 690
Score = 161 bits (408), Expect = 9e-40
Identities = 107/375 (28%), Positives = 193/375 (51%), Gaps = 14/375 (3%)
Query: 15 LPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENISK 74
LP+ +L+IF +L + + C Q++ AW ++ S W ID + + + + + + +
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 217
Query: 75 RCGGFLRKLSLRGCIGVGDSSLKTF--AQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKL 132
R + +L+ RGC+ KTF +CRN++ LN++ C TD + +S C +
Sbjct: 218 RWRLNVLRLNFRGCL----LRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISEGCPGV 273
Query: 133 KHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALV--RGCRGLKALLLR 190
L+L++ +ITN +++ + NL+ L+L++C + T G++ L GC L L L
Sbjct: 274 LCLNLSN-TTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLS 332
Query: 191 GCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDA 250
GCTQ+ + ++I N C ++ L + +TD V + C R+ +L +G +++D
Sbjct: 333 GCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDC 392
Query: 251 SLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIH 310
+ A L+ +L+ + +TDA F + +N L + + +C ITDS+L LS
Sbjct: 393 TFRA--LSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLS-P 449
Query: 311 CPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGLE 369
+L L+L++C I D G+ + R+R L L NC+ ++D ++ L E C L
Sbjct: 450 LKQLTVLNLANCVRIGDMGLKQFLDGPAS-MRIRELNLSNCVRLSDASVMKLSERCPNLN 508
Query: 370 RLELYDCQQVTRAGI 384
L L +C+ +T GI
Sbjct: 509 YLSLRNCEHLTAQGI 523
Score = 105 bits (261), Expect = 1e-22
Identities = 78/258 (30%), Positives = 126/258 (48%), Gaps = 25/258 (9%)
Query: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
LRK+ G V D+S K +N N+ H+ + C ITDS+ SLS +L L+L +
Sbjct: 402 LRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPL-KQLTVLNLAN 460
Query: 140 CVSITNSSLKGISEGCRNLEY--LNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLED 197
CV I + LK +G ++ LNLS C +++ + L C L L LR C L
Sbjct: 461 CVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTA 520
Query: 198 EALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGL 257
+ + +I N LVS++L S + I++EG+ + R +L+ L +S C +TD +
Sbjct: 521 QGIGYIVNI-FSLVSIDL-SGTDISNEGLNVLSRH-KKLKELSVSECYRITDDGI----- 572
Query: 258 NCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQAL 317
+TD+ +L+ CH L +D+ C+L+TD L L I C +L+ L
Sbjct: 573 --------------QITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRIL 618
Query: 318 SLSHCELITDDGILHLSN 335
+ +C I+ +S+
Sbjct: 619 KMQYCTNISKKAAQRMSS 636
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/113 (26%), Positives = 54/113 (47%), Gaps = 11/113 (9%)
Query: 55 IDLFNFQIDVEGRVVENISKRCGGFLRKLSLRGC-------IGVGDSSLKTFAQNCRNIE 107
IDL I EG V + K+ L++LS+ C I + DS+++ + C +
Sbjct: 535 IDLSGTDISNEGLNVLSRHKK----LKELSVSECYRITDDGIQITDSAMEMLSAKCHYLH 590
Query: 108 HLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEY 160
L+++GC +TD L C +L+ L + C +I+ + + +S + EY
Sbjct: 591 ILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMSSKVQQQEY 643
>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
[Homo sapiens]
Length = 735
Score = 161 bits (408), Expect = 9e-40
Identities = 107/375 (28%), Positives = 193/375 (51%), Gaps = 14/375 (3%)
Query: 15 LPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENISK 74
LP+ +L+IF +L + + C Q++ AW ++ S W ID + + + + + + +
Sbjct: 158 LPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQ 217
Query: 75 RCGGFLRKLSLRGCIGVGDSSLKTF--AQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKL 132
R + +L+ RGC+ KTF +CRN++ LN++ C TD + +S C +
Sbjct: 218 RWRLNVLRLNFRGCL----LRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISEGCPGV 273
Query: 133 KHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALV--RGCRGLKALLLR 190
L+L++ +ITN +++ + NL+ L+L++C + T G++ L GC L L L
Sbjct: 274 LCLNLSN-TTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLS 332
Query: 191 GCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDA 250
GCTQ+ + ++I N C ++ L + +TD V + C R+ +L +G +++D
Sbjct: 333 GCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDC 392
Query: 251 SLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIH 310
+ A L+ +L+ + +TDA F + +N L + + +C ITDS+L LS
Sbjct: 393 TFRA--LSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLS-P 449
Query: 311 CPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGLE 369
+L L+L++C I D G+ + R+R L L NC+ ++D ++ L E C L
Sbjct: 450 LKQLTVLNLANCVRIGDMGLKQFLDGPAS-MRIRELNLSNCVRLSDASVMKLSERCPNLN 508
Query: 370 RLELYDCQQVTRAGI 384
L L +C+ +T GI
Sbjct: 509 YLSLRNCEHLTAQGI 523
Score = 136 bits (342), Expect = 4e-32
Identities = 86/283 (30%), Positives = 141/283 (49%), Gaps = 30/283 (10%)
Query: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRF----------- 128
LRK+ G V D+S K +N N+ H+ + C ITDS+ SLS
Sbjct: 402 LRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANC 461
Query: 129 ----------------CSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKD 172
+++ L+L++CV ++++S+ +SE C NL YL+L C+ +T
Sbjct: 462 VRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQ 521
Query: 173 GIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRG 232
GI +V L ++ L G T + +E L + + +L L++ C RITD+G+ C+
Sbjct: 522 GIGYIVN-IFSLVSIDLSG-TDISNEGLNVLSRH-KKLKELSVSECYRITDDGIQAFCKS 578
Query: 233 CHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMD 292
L+ L +S CS L+D + AL + C L L A C +TD+ +L+ CH L +D
Sbjct: 579 SLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILD 638
Query: 293 LEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSN 335
+ C+L+TD L L I C +L+ L + +C I+ +S+
Sbjct: 639 ISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMSS 681
Score = 121 bits (304), Expect = 1e-27
Identities = 97/357 (27%), Positives = 168/357 (47%), Gaps = 35/357 (9%)
Query: 61 QIDVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDS 120
QI V+G I+ C G + L++ + D+ +K + C I L G I+D
Sbjct: 336 QISVQG--FRYIANSCTGIMH-LTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDC 392
Query: 121 TCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRG 180
T +LS KL+ + +T++S K I + NL ++ ++ C IT + +L
Sbjct: 393 TFRALS--ACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSL-SP 449
Query: 181 CRGLKALLLRGCTQLEDEALKHIQN--YCHELVSLNLQSCSRITDEGVVQICRGCHRLQA 238
+ L L L C ++ D LK + + LNL +C R++D V+++ C L
Sbjct: 450 LKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNY 509
Query: 239 LCLSGCSNLT----------------DASLTAL---GLNC----PRLQILEAARCSHLTD 275
L L C +LT D S T + GLN +L+ L + C +TD
Sbjct: 510 LSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITD 569
Query: 276 AGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSN 335
G ++ LE +D+ C ++D + L+I+C L +LS++ C ITD + LS
Sbjct: 570 DGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLS- 628
Query: 336 STCGHERLRVLELDNCLLITDVALEHLE-NCRGLERLELYDCQQVTRAGIKRMRAQL 391
+ C + L +L++ C+L+TD LE L+ C+ L L++ C +++ +RM +++
Sbjct: 629 AKCHY--LHILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMSSKV 683
Score = 47.8 bits (112), Expect = 2e-05
Identities = 22/81 (27%), Positives = 42/81 (51%)
Query: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
L LS+ GC + DS+++ + C + L+++GC +TD L C +L+ L +
Sbjct: 608 LTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQY 667
Query: 140 CVSITNSSLKGISEGCRNLEY 160
C +I+ + + +S + EY
Sbjct: 668 CTNISKKAAQRMSSKVQQQEY 688
>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
Length = 621
Score = 119 bits (297), Expect = 7e-27
Identities = 104/394 (26%), Positives = 169/394 (42%), Gaps = 63/394 (15%)
Query: 14 KLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENIS 73
KLP EL+ I + L + LCR AQ K + D + ++L + ++
Sbjct: 282 KLPYELIQLILNHLTLPDLCRLAQTCKLLSQHCCDPLQYIHLNLQPYWAKLD-------- 333
Query: 74 KRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFC---- 129
D+SL+ C ++ LNL+ + SRF
Sbjct: 334 -------------------DTSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCG 374
Query: 130 SKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLL 189
S+L L+L+ + + L+ ISE C NL+ LNLS CD++ + + C + +L
Sbjct: 375 SELVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLY 434
Query: 190 RGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTD 249
R T++E AL I N+C EL L+L SC I D V+
Sbjct: 435 R--TKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIA--------------------- 471
Query: 250 ASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDST--LIQL 307
+ +G C +L+ L+ RC ++T+ G LA C LE++DL C + ST +L
Sbjct: 472 ---SMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRL 528
Query: 308 SIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCR 366
+ P LQ L L+ + D I L+ C RL+ L++ +++ +L L E+C+
Sbjct: 529 AHQLPNLQKLFLTANRSVCDTDIDELA---CNCTRLQQLDILGTRMVSPASLRKLLESCK 585
Query: 367 GLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYF 400
L L++ C Q+ + + A P V + F
Sbjct: 586 DLSLLDVSFCSQIDNRAVLELNASFPKVFIKKSF 619
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/168 (25%), Positives = 80/168 (47%), Gaps = 10/168 (5%)
Query: 10 LINKKLPKELLLRIFSF---LDIVTLCRCAQISKAWNILALDGSNWQRI---DLFNFQID 63
L K+ + LL I +F L ++L C I I ++ G+ +++ DL+ +
Sbjct: 433 LYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNI 492
Query: 64 VEGRVVENISKRCGGFLRKLSLRGCIGVGDSS--LKTFAQNCRNIEHLNLNGCTKITDST 121
E + E ++ C L +L L C + S+ A N++ L L + D+
Sbjct: 493 TENGIAE-LASGCP-LLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTD 550
Query: 122 CYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQI 169
L+ C++L+ LD+ ++ +SL+ + E C++L L++S+C QI
Sbjct: 551 IDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQI 598
>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
Length = 479
Score = 100 bits (250), Expect = 2e-21
Identities = 72/234 (30%), Positives = 108/234 (46%), Gaps = 3/234 (1%)
Query: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
+ LS+ CI V D ++ +Q N+ L+L + Y +R L L S
Sbjct: 244 ITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLS 303
Query: 140 CVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEA 199
C ITN + + NL L+LS C ++T DG+E + R L++L L C ++ D A
Sbjct: 304 CWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMA 363
Query: 200 LKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNC 259
L+++ H L L L C RITD G+ + L++L L C + D L L L
Sbjct: 364 LEYVACDLHRLEELVLDRCVRITDTGLSYLST-MSSLRSLYLRWCCQVQDFGLKHL-LAL 421
Query: 260 PRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPK 313
L++L A C LT G + L + ELE+++L C T S H P+
Sbjct: 422 GSLRLLSPAGCPLLTTTGLSGLVQ-LQELEELELTNCPGATPELFKYFSQHLPR 474
Score = 99.8 bits (247), Expect = 4e-21
Identities = 104/419 (24%), Positives = 167/419 (39%), Gaps = 52/419 (12%)
Query: 17 KELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRI-------DLFNFQIDVEGRVV 69
+++L +F + C AQ+ KAW + W + +L+N E V
Sbjct: 99 EKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFV 158
Query: 70 ENISKRCGGFLRKLSLRG-----CIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYS 124
L+ + RG +GV D + F N Y+
Sbjct: 159 N---------LQGFAARGFEGFCLVGVSDLDICEFIDN--------------------YA 189
Query: 125 LSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGL 184
LS+ K L ++ IT++ L+ + E + + L LS C+ T+ G+ + + +
Sbjct: 190 LSKKGVKAMSLKRST---ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSA--RI 244
Query: 185 KALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQI-CRGCHRLQALCLSG 243
+L + C + D+A+ I L L+LQ+ +TD + R H L L
Sbjct: 245 TSLSVSDCINVADDAIAAISQLLPNLAELSLQAY-HVTDTALAYFTARQGHSTHTLRLLS 303
Query: 244 CSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDST 303
C +T+ + + + P L L + CS +TD G L+A N +L +DL C ITD
Sbjct: 304 CWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMA 363
Query: 304 LIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLE 363
L ++ +L+ L L C ITD G+ +LS + LR L L C + D L+HL
Sbjct: 364 LEYVACDLHRLEELVLDRCVRITDTGLSYLSTMS----SLRSLYLRWCCQVQDFGLKHLL 419
Query: 364 NCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVI 422
L L C +T G+ + ++ P P Q L RC VI
Sbjct: 420 ALGSLRLLSPAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVI 478
>gi|164663798 antagonist of mitotic exit network 1 homolog [Homo
sapiens]
Length = 258
Score = 95.5 bits (236), Expect = 8e-20
Identities = 70/230 (30%), Positives = 118/230 (51%), Gaps = 39/230 (16%)
Query: 104 RNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNL 163
R I+ +++ G +ITDS + +++ LDL SC I++++L +S CR L+ LNL
Sbjct: 39 RLIKIMSMQG--QITDSNISEILH--PEVQTLDLRSC-DISDAALLHLSN-CRKLKKLNL 92
Query: 164 SWCD----QITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCS 219
+ +T +GI+A+ C +Y HE +L+ C
Sbjct: 93 NASKGNRVSVTSEGIKAVASSC-----------------------SYLHEA---SLKRCC 126
Query: 220 RITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFT 279
+TDEGVV + C L+ + L GC ++TD SL ALG NCP LQ ++ + + ++D+G
Sbjct: 127 NLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKNCPFLQCVDFS-ATQVSDSGVI 185
Query: 280 LLARN--CHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITD 327
L +LE++ + C+ +TD + + +CP+++ L C LITD
Sbjct: 186 ALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITD 235
Score = 92.8 bits (229), Expect = 5e-19
Identities = 67/215 (31%), Positives = 102/215 (47%), Gaps = 12/215 (5%)
Query: 163 LSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCS--- 219
+S QIT I ++ ++ L LR C + D AL H+ N C +L LNL +
Sbjct: 44 MSMQGQITDSNISEILHP--EVQTLDLRSC-DISDAALLHLSN-CRKLKKLNLNASKGNR 99
Query: 220 -RITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGF 278
+T EG+ + C L L C NLTD + AL LNC L+I++ C +TD
Sbjct: 100 VSVTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSL 159
Query: 279 TLLARNCHELEKMDLEECILITDSTLIQLSIHCPK-LQALSLSHCELITDDGILHLSNST 337
L +NC L+ +D + + +S C K L+ + + HC +TD G + +
Sbjct: 160 HALGKNCPFLQCVDFSATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTD-GAVEAVLTY 218
Query: 338 CGHERLRVLELDNCLLITDVALEHLENCRGLERLE 372
C ++R+L C LITD + E LE G +L+
Sbjct: 219 C--PQIRILLFHGCPLITDHSREVLEQLVGPNKLK 251
Score = 73.6 bits (179), Expect = 3e-13
Identities = 46/150 (30%), Positives = 75/150 (50%), Gaps = 7/150 (4%)
Query: 80 LRKLSLRGCIG----VGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHL 135
L+KL+L G V +K A +C + +L C +TD +L+ C LK +
Sbjct: 87 LKKLNLNASKGNRVSVTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKII 146
Query: 136 DLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRG--CRGLKALLLRGCT 193
DL C+SIT+ SL + + C L+ ++ S Q++ G+ ALV G + L+ + + C
Sbjct: 147 DLGGCLSITDVSLHALGKNCPFLQCVDFS-ATQVSDSGVIALVSGPCAKKLEEIHMGHCV 205
Query: 194 QLEDEALKHIQNYCHELVSLNLQSCSRITD 223
L D A++ + YC ++ L C ITD
Sbjct: 206 NLTDGAVEAVLTYCPQIRILLFHGCPLITD 235
Score = 68.9 bits (167), Expect = 8e-12
Identities = 48/200 (24%), Positives = 94/200 (47%), Gaps = 8/200 (4%)
Query: 62 IDVEGRVVE-NISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGC----TK 116
+ ++G++ + NIS+ ++ L LR C + D++L + NCR ++ LNLN
Sbjct: 44 MSMQGQITDSNISEILHPEVQTLDLRSC-DISDAALLHLS-NCRKLKKLNLNASKGNRVS 101
Query: 117 ITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEA 176
+T +++ CS L L C ++T+ + ++ C+ L+ ++L C IT + A
Sbjct: 102 VTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHA 161
Query: 177 LVRGCRGLKALLLRGCTQLEDEALKHIQNYC-HELVSLNLQSCSRITDEGVVQICRGCHR 235
L + C L+ + + + + C +L +++ C +TD V + C +
Sbjct: 162 LGKNCPFLQCVDFSATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQ 221
Query: 236 LQALCLSGCSNLTDASLTAL 255
++ L GC +TD S L
Sbjct: 222 IRILLFHGCPLITDHSREVL 241
Score = 68.2 bits (165), Expect = 1e-11
Identities = 39/156 (25%), Positives = 79/156 (50%), Gaps = 8/156 (5%)
Query: 61 QIDVEGRVVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDS 120
++ V ++ ++ C +L + SL+ C + D + A NC+ ++ ++L GC ITD
Sbjct: 99 RVSVTSEGIKAVASSCS-YLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDV 157
Query: 121 TCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEG--CRNLEYLNLSWCDQITKDGIEALV 178
+ ++L + C L+ +D S +++S + + G + LE +++ C +T +EA++
Sbjct: 158 SLHALGKNCPFLQCVDF-SATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVL 216
Query: 179 RGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLN 214
C ++ LL GC + D H + +LV N
Sbjct: 217 TYCPQIRILLFHGCPLITD----HSREVLEQLVGPN 248
Score = 54.3 bits (129), Expect = 2e-07
Identities = 38/130 (29%), Positives = 72/130 (55%), Gaps = 11/130 (8%)
Query: 260 PRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEEC----ILITDSTLIQLSIHCPKLQ 315
P +Q L+ C ++DA L+ NC +L+K++L + +T + ++ C L
Sbjct: 61 PEVQTLDLRSCD-ISDAALLHLS-NCRKLKKLNLNASKGNRVSVTSEGIKAVASSCSYLH 118
Query: 316 ALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGLERLELY 374
SL C +TD+G++ L+ + + L++++L CL ITDV+L L +NC L+ ++ +
Sbjct: 119 EASLKRCCNLTDEGVVALALNC---QLLKIIDLGGCLSITDVSLHALGKNCPFLQCVD-F 174
Query: 375 DCQQVTRAGI 384
QV+ +G+
Sbjct: 175 SATQVSDSGV 184
Score = 34.3 bits (77), Expect = 0.22
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 10/74 (13%)
Query: 325 ITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQ----QVT 380
ITD I + H ++ L+L +C I+D AL HL NCR L++L L + VT
Sbjct: 50 ITDSNISEIL-----HPEVQTLDLRSCD-ISDAALLHLSNCRKLKKLNLNASKGNRVSVT 103
Query: 381 RAGIKRMRAQLPHV 394
GIK + + ++
Sbjct: 104 SEGIKAVASSCSYL 117
>gi|254039600 F-box and leucine-rich repeat protein 17 [Homo
sapiens]
Length = 303
Score = 93.2 bits (230), Expect = 4e-19
Identities = 68/264 (25%), Positives = 116/264 (43%), Gaps = 26/264 (9%)
Query: 75 RCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKH 134
+C G LR + R C + D+S+ A +C ++ +++ K+TD L C +LK
Sbjct: 12 KCPGLLRYTAYR-CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKD 70
Query: 135 LDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGC------------- 181
+ C I++ + I++GC L+ + + +T ++A C
Sbjct: 71 IHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSV 130
Query: 182 -----------RGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQIC 230
R L +L LR T+L++E + I C L SLNL I D V I
Sbjct: 131 TSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIA 190
Query: 231 RGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEK 290
+ L+ L L C +TD +L A+G ++ ++ C +TD G TL+A++ L
Sbjct: 191 KEGQNLKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRY 249
Query: 291 MDLEECILITDSTLIQLSIHCPKL 314
+ L C + + T+ QL P +
Sbjct: 250 LGLMRCDKVNEVTVEQLVQQYPHI 273
Score = 90.9 bits (224), Expect = 2e-18
Identities = 60/272 (22%), Positives = 130/272 (47%), Gaps = 6/272 (2%)
Query: 91 VGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKG 150
+ D+ + A C + C +++D++ +++ C L+ + + + +T+ LK
Sbjct: 1 MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
Query: 151 ISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHEL 210
+ CR L+ ++ C +I+ +G+ + +GC L+ + ++ + D+++K +C EL
Sbjct: 61 LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPEL 120
Query: 211 VSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARC 270
+ CS +T +GV+ + + L +L L + L + ++ + C L L
Sbjct: 121 QYVGFMGCS-VTSKGVIHLTK-LRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLN 178
Query: 271 SHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI 330
+ D ++A+ L+++ L C ITD LI + + ++ + + C+ ITD G
Sbjct: 179 WIINDRCVEVIAKEGQNLKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGA 237
Query: 331 LHLSNSTCGHERLRVLELDNCLLITDVALEHL 362
++ S+ + LR L L C + +V +E L
Sbjct: 238 TLIAQSS---KSLRYLGLMRCDKVNEVTVEQL 266
Score = 83.6 bits (205), Expect = 3e-16
Identities = 44/169 (26%), Positives = 85/169 (50%), Gaps = 8/169 (4%)
Query: 207 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILE 266
C L+ C +++D ++ + C LQ + + LTD L LG C L+ +
Sbjct: 13 CPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIH 72
Query: 267 AARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELIT 326
+C ++D G ++A+ C +L+++ ++E L+TD ++ + HCP+LQ + C +T
Sbjct: 73 FGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCS-VT 131
Query: 327 DDGILHLS--NSTCGHERLRVLELDNCLLITDVALEHLENCRGLERLEL 373
G++HL+ + + + ELDN + +E ++ C+ L L L
Sbjct: 132 SKGVIHLTKLRNLSSLDLRHITELDN-----ETVMEIVKRCKNLSSLNL 175
Score = 82.0 bits (201), Expect = 9e-16
Identities = 60/219 (27%), Positives = 109/219 (49%), Gaps = 7/219 (3%)
Query: 166 CDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEG 225
C Q++ I A+ C L+ + + +L DE LK + + C EL ++ C +I+DEG
Sbjct: 24 CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEG 83
Query: 226 VVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNC 285
++ I +GC +LQ + + +TD S+ A +CP LQ + CS +T G L +
Sbjct: 84 MIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCS-VTSKGVIHLTK-L 141
Query: 286 HELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRV 345
L +DL + + T++++ C L +L+L +I D + ++ + L+
Sbjct: 142 RNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKE---GQNLKE 198
Query: 346 LELDNCLLITDVALEHL-ENCRGLERLELYDCQQVTRAG 383
L L +C ITD AL + +E +++ C+++T G
Sbjct: 199 LYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQG 236
Score = 65.9 bits (159), Expect = 7e-11
Identities = 42/153 (27%), Positives = 68/153 (44%), Gaps = 4/153 (2%)
Query: 221 ITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTL 280
++D GV + C L C L+D S+ A+ +CP LQ + LTD G
Sbjct: 1 MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
Query: 281 LARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGH 340
L C EL+ + +C I+D +I ++ C KLQ + + +L+TD + +
Sbjct: 61 LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHC--- 117
Query: 341 ERLRVLELDNCLLITDVALEHLENCRGLERLEL 373
L+ + C +T + HL R L L+L
Sbjct: 118 PELQYVGFMGC-SVTSKGVIHLTKLRNLSSLDL 149
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 80.5 bits (197), Expect = 3e-15
Identities = 78/281 (27%), Positives = 130/281 (46%), Gaps = 25/281 (8%)
Query: 6 NDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLF--NFQID 63
N G+ LP ELLL IFS L + L + + + K W LA D S WQ +DL N D
Sbjct: 91 NFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPD 150
Query: 64 VEGRVVEN--ISKRCGGF--------------LRKLSLRGCIGVGDSSLKTFAQNCRNIE 107
V GR++ I+ RC ++ + L + + S+L C ++
Sbjct: 151 VTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSV-IEVSTLHGILSQCSKLQ 209
Query: 108 HLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCD 167
+L+L G +++D +L++ S L L+L+ C + +L+ + C L+ LNLSWC
Sbjct: 210 NLSLEG-LRLSDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCF 267
Query: 168 QITKDGIE-ALVRGCRGLKALLLRGCTQ-LEDEALKHIQNYCHELVSLNLQSCSRITDEG 225
T+ ++ A+ + L L G + L+ L + C LV L+L + ++
Sbjct: 268 DFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDC 327
Query: 226 VVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILE 266
+ + + LQ L LS C ++ +L LG P L+ L+
Sbjct: 328 FQEFFQ-LNYLQHLSLSRCYDIIPETLLELG-EIPTLKTLQ 366
Score = 48.9 bits (115), Expect = 9e-06
Identities = 44/178 (24%), Positives = 75/178 (42%), Gaps = 35/178 (19%)
Query: 68 VVENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITD-------- 119
+V ++K L +L+L GC G + +L+T +C ++ LNL+ C T+
Sbjct: 222 IVNTLAKNSN--LVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVA 279
Query: 120 --------------------STCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLE 159
S +L R C L HLDL+ V + N + + L+
Sbjct: 280 HVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDCFQEFFQ-LNYLQ 338
Query: 160 YLNLSWCDQITKDGIEAL--VRGCRGLKA--LLLRGCTQLEDEALKHIQNYCHELVSL 213
+L+LS C I + + L + + L+ ++ G QL EAL H+Q C ++
Sbjct: 339 HLSLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEALPHLQINCSHFTTI 396
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/227 (24%), Positives = 97/227 (42%), Gaps = 33/227 (14%)
Query: 195 LEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTA 254
+E L I + C +L +L+L+ R++D V + + + L L LSGCS ++ +L
Sbjct: 193 IEVSTLHGILSQCSKLQNLSLEGL-RLSDPIVNTLAKNSN-LVRLNLSGCSGFSEFALQT 250
Query: 255 LGLNCPRLQILEAARCSHLTDAGFTLLARNCHE-------------LEKMDLEECILITD 301
L +C RL L + C T+ + + E L+K DL
Sbjct: 251 LLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDL-------- 302
Query: 302 STLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEH 361
STL++ CP L L LS ++ +D L+ L L C I L
Sbjct: 303 STLVR---RCPNLVHLDLSDSVMLKNDCFQEFFQL----NYLQHLSLSRCYDIIPETLLE 355
Query: 362 LENCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVH-AYFAPVTPPT 407
L L+ L+++ V ++ ++ LPH++++ ++F + PT
Sbjct: 356 LGEIPTLKTLQVFGI--VPDGTLQLLKEALPHLQINCSHFTTIARPT 400
Score = 32.7 bits (73), Expect = 0.64
Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 10/108 (9%)
Query: 288 LEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLE 347
++ MDL + I STL + C KLQ LSL L D I+ N+ + L L
Sbjct: 183 VQHMDLSNSV-IEVSTLHGILSQCSKLQNLSLEGLRL--SDPIV---NTLAKNSNLVRLN 236
Query: 348 LDNCLLITDVALEH-LENCRGLERLELYDCQQVTRAGIKRMRAQLPHV 394
L C ++ AL+ L +C L+ L L C T K ++ + HV
Sbjct: 237 LSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTE---KHVQVAVAHV 281
>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
sapiens]
Length = 300
Score = 79.0 bits (193), Expect = 8e-15
Identities = 50/192 (26%), Positives = 92/192 (47%), Gaps = 2/192 (1%)
Query: 94 SSLKTFAQNCRNIEHLNLNGCTK-ITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGIS 152
++L ++ ++ L L C + ++D + +L+ + L C ++ +L ++
Sbjct: 77 AALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALA 136
Query: 153 EGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHI-QNYCHELV 211
EGC L+ L+L+ CD + + L C L+ L L C QL+DEA+ ++ Q L
Sbjct: 137 EGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLR 196
Query: 212 SLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCS 271
SL+L + + D V ++ R C L L L+GC + + L CP L+ L C
Sbjct: 197 SLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCH 256
Query: 272 HLTDAGFTLLAR 283
H+ ++ + L +
Sbjct: 257 HVAESSLSRLRK 268
Score = 73.9 bits (180), Expect = 2e-13
Identities = 68/243 (27%), Positives = 108/243 (44%), Gaps = 21/243 (8%)
Query: 148 LKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYC 207
L+ +S R+L L+L+ + D + + R A LLR L++ AL C
Sbjct: 44 LQRVSRAFRSLVQLHLAGLRRF--DAAQVGPQIPRAALARLLRDAEGLQELALAP----C 97
Query: 208 HELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEA 267
HE +S DE +V + +L+++ L GC L+ +L AL CPRLQ L
Sbjct: 98 HEWLS----------DEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSL 147
Query: 268 ARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLS-IHCPKLQALSLSHCELIT 326
A C + LA C LE++DL C + D ++ L+ L++LSL+ +
Sbjct: 148 AHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVG 207
Query: 327 DDGILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGLERLELYDCQQVTRAGIK 385
D + L+ + L L+L CL + + L E C L L + C V + +
Sbjct: 208 DAAVQELARNC---PELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLS 264
Query: 386 RMR 388
R+R
Sbjct: 265 RLR 267
Score = 66.6 bits (161), Expect = 4e-11
Identities = 53/204 (25%), Positives = 86/204 (42%), Gaps = 13/204 (6%)
Query: 200 LKHIQNYCHELVSLNLQSCSR---------ITDEGVVQICRGCHRLQALCLSGCSN-LTD 249
L+ + LV L+L R I + ++ R LQ L L+ C L+D
Sbjct: 44 LQRVSRAFRSLVQLHLAGLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSD 103
Query: 250 ASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSI 309
L + P+L+ + C L+ LA C L+++ L C + L L+
Sbjct: 104 EDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLAD 163
Query: 310 HCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGL 368
CP L+ L L+ C + D+ I++L+ LR L L + D A++ L NC L
Sbjct: 164 RCPALEELDLTACRQLKDEAIVYLAQRRGAG--LRSLSLAVNANVGDAAVQELARNCPEL 221
Query: 369 ERLELYDCQQVTRAGIKRMRAQLP 392
L+L C +V G++ + P
Sbjct: 222 HHLDLTGCLRVGSDGVRTLAEYCP 245
Score = 62.4 bits (150), Expect = 8e-10
Identities = 36/151 (23%), Positives = 73/151 (48%), Gaps = 1/151 (0%)
Query: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
LR ++L GC + +L A+ C ++ L+L C + L+ C L+ LDLT+
Sbjct: 116 LRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTA 175
Query: 140 CVSITNSSLKGISE-GCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDE 198
C + + ++ +++ L L+L+ + ++ L R C L L L GC ++ +
Sbjct: 176 CRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSD 235
Query: 199 ALKHIQNYCHELVSLNLQSCSRITDEGVVQI 229
++ + YC L SL ++ C + + + ++
Sbjct: 236 GVRTLAEYCPVLRSLRVRHCHHVAESSLSRL 266
Score = 55.1 bits (131), Expect = 1e-07
Identities = 26/77 (33%), Positives = 44/77 (57%)
Query: 72 ISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSK 131
+++R G LR LSL VGD++++ A+NC + HL+L GC ++ +L+ +C
Sbjct: 187 LAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPV 246
Query: 132 LKHLDLTSCVSITNSSL 148
L+ L + C + SSL
Sbjct: 247 LRSLRVRHCHHVAESSL 263
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 76.3 bits (186), Expect = 5e-14
Identities = 73/267 (27%), Positives = 123/267 (46%), Gaps = 24/267 (8%)
Query: 6 NDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLF--NFQID 63
N G+ LP ELLL IFS L + L + + + K W LA D S WQ +DL N D
Sbjct: 91 NFPGVSWDSLPDELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPD 150
Query: 64 VEGRVVEN--ISKRCGGF--------------LRKLSLRGCIGVGDSSLKTFAQNCRNIE 107
V GR++ I+ RC ++ + L + + S+L C ++
Sbjct: 151 VTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSV-IEVSTLHGILSQCSKLQ 209
Query: 108 HLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCD 167
+L+L G +++D +L++ S L L+L+ C + +L+ + C L+ LNLSWC
Sbjct: 210 NLSLEG-LRLSDPIVNTLAK-NSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCF 267
Query: 168 QITKDGIE-ALVRGCRGLKALLLRGCTQ-LEDEALKHIQNYCHELVSLNLQSCSRITDEG 225
T+ ++ A+ + L L G + L+ L + C LV L+L + ++
Sbjct: 268 DFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHLDLSDSVMLKNDC 327
Query: 226 VVQICRGCHRLQALCLSGCSNLTDASL 252
+ + + LQ L LS C ++ +L
Sbjct: 328 FQEFFQ-LNYLQHLSLSRCYDIIPETL 353
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/165 (24%), Positives = 68/165 (41%), Gaps = 31/165 (18%)
Query: 195 LEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTA 254
+E L I + C +L +L+L+ R++D V + + + L L LSGCS ++ +L
Sbjct: 193 IEVSTLHGILSQCSKLQNLSLEGL-RLSDPIVNTLAKNSN-LVRLNLSGCSGFSEFALQT 250
Query: 255 LGLNCPRLQILEAARCSHLTD----------------------------AGFTLLARNCH 286
L +C RL L + C T+ + + L R C
Sbjct: 251 LLSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTLVRRCP 310
Query: 287 ELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGIL 331
L +DL + +++ + Q LQ LSLS C I + +L
Sbjct: 311 NLVHLDLSDSVMLKND-CFQEFFQLNYLQHLSLSRCYDIIPETLL 354
Score = 32.7 bits (73), Expect = 0.64
Identities = 34/108 (31%), Positives = 49/108 (45%), Gaps = 10/108 (9%)
Query: 288 LEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLE 347
++ MDL + I STL + C KLQ LSL L D I+ N+ + L L
Sbjct: 183 VQHMDLSNSV-IEVSTLHGILSQCSKLQNLSLEGLRL--SDPIV---NTLAKNSNLVRLN 236
Query: 348 LDNCLLITDVALEH-LENCRGLERLELYDCQQVTRAGIKRMRAQLPHV 394
L C ++ AL+ L +C L+ L L C T K ++ + HV
Sbjct: 237 LSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTE---KHVQVAVAHV 281
>gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]
Length = 223
Score = 71.2 bits (173), Expect = 2e-12
Identities = 39/136 (28%), Positives = 76/136 (55%), Gaps = 1/136 (0%)
Query: 132 LKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRG 191
L+ LDLT+C +T++SL + + + L L+LS ++T +G+ A+ RGC L+ L L
Sbjct: 77 LQELDLTACSKLTDASLAKVLQFLQ-LRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
Query: 192 CTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDAS 251
C++L D+ + L LNL SCS++ ++ + I + C +L+ L ++ C + A+
Sbjct: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAA 195
Query: 252 LTALGLNCPRLQILEA 267
+ P++ +++
Sbjct: 196 VRRFQAQLPQVSCVQS 211
Score = 70.9 bits (172), Expect = 2e-12
Identities = 40/136 (29%), Positives = 67/136 (49%), Gaps = 1/136 (0%)
Query: 182 RGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCL 241
R L+ L L C++L D +L + + +L L+L +TD G+V + RGC L+ L L
Sbjct: 75 RALQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
Query: 242 SGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITD 301
S CS L+D + PRLQ L + CS L + + + C +L +D+ C I
Sbjct: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINM 193
Query: 302 STLIQLSIHCPKLQAL 317
+ + + P++ +
Sbjct: 194 AAVRRFQAQLPQVSCV 209
Score = 69.7 bits (169), Expect = 5e-12
Identities = 54/187 (28%), Positives = 90/187 (48%), Gaps = 15/187 (8%)
Query: 209 ELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAA 268
+L SL+L CS + ++ H+ C SL L LQ L+
Sbjct: 34 QLASLSLAHCSSLKSRPELE-----HQASGT-KDACPEPQGPSLLTLRA----LQELDLT 83
Query: 269 RCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDD 328
CS LTDA + + +L ++ L +TD+ L+ ++ CP L+ L+LSHC ++D
Sbjct: 84 ACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDK 142
Query: 329 GILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGLERLELYDCQQVTRAGIKRM 387
G ++S RL+ L L +C + + L+ + + CR L L++ C + A ++R
Sbjct: 143 GWAQAASSW---PRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVRRF 199
Query: 388 RAQLPHV 394
+AQLP V
Sbjct: 200 QAQLPQV 206
Score = 63.5 bits (153), Expect = 3e-10
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 1/118 (0%)
Query: 104 RNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNL 163
R ++ L+L C+K+TD++ + +F +L+ L L+ +T++ L ++ GC +LE+L L
Sbjct: 75 RALQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
Query: 164 SWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRI 221
S C +++ G L+ L L C+QL ++ L I C +L L++ +C I
Sbjct: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGI 191
Score = 60.5 bits (145), Expect = 3e-09
Identities = 34/125 (27%), Positives = 67/125 (53%), Gaps = 1/125 (0%)
Query: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
L++L L C + D+SL Q + + L+L+ ++TD+ +++R C L+HL L+
Sbjct: 77 LQELDLTACSKLTDASLAKVLQFLQ-LRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
Query: 140 CVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEA 199
C +++ + L++LNLS C Q+ + ++A+ + CR L+ L + C + A
Sbjct: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAA 195
Query: 200 LKHIQ 204
++ Q
Sbjct: 196 VRRFQ 200
>gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]
Length = 223
Score = 71.2 bits (173), Expect = 2e-12
Identities = 39/136 (28%), Positives = 76/136 (55%), Gaps = 1/136 (0%)
Query: 132 LKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRG 191
L+ LDLT+C +T++SL + + + L L+LS ++T +G+ A+ RGC L+ L L
Sbjct: 77 LQELDLTACSKLTDASLAKVLQFLQ-LRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
Query: 192 CTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDAS 251
C++L D+ + L LNL SCS++ ++ + I + C +L+ L ++ C + A+
Sbjct: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAA 195
Query: 252 LTALGLNCPRLQILEA 267
+ P++ +++
Sbjct: 196 VRRFQAQLPQVSCVQS 211
Score = 70.9 bits (172), Expect = 2e-12
Identities = 40/136 (29%), Positives = 67/136 (49%), Gaps = 1/136 (0%)
Query: 182 RGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCL 241
R L+ L L C++L D +L + + +L L+L +TD G+V + RGC L+ L L
Sbjct: 75 RALQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
Query: 242 SGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITD 301
S CS L+D + PRLQ L + CS L + + + C +L +D+ C I
Sbjct: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINM 193
Query: 302 STLIQLSIHCPKLQAL 317
+ + + P++ +
Sbjct: 194 AAVRRFQAQLPQVSCV 209
Score = 69.7 bits (169), Expect = 5e-12
Identities = 54/187 (28%), Positives = 90/187 (48%), Gaps = 15/187 (8%)
Query: 209 ELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAA 268
+L SL+L CS + ++ H+ C SL L LQ L+
Sbjct: 34 QLASLSLAHCSSLKSRPELE-----HQASGT-KDACPEPQGPSLLTLRA----LQELDLT 83
Query: 269 RCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDD 328
CS LTDA + + +L ++ L +TD+ L+ ++ CP L+ L+LSHC ++D
Sbjct: 84 ACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDK 142
Query: 329 GILHLSNSTCGHERLRVLELDNCLLITDVALEHL-ENCRGLERLELYDCQQVTRAGIKRM 387
G ++S RL+ L L +C + + L+ + + CR L L++ C + A ++R
Sbjct: 143 GWAQAASSW---PRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVRRF 199
Query: 388 RAQLPHV 394
+AQLP V
Sbjct: 200 QAQLPQV 206
Score = 63.5 bits (153), Expect = 3e-10
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 1/118 (0%)
Query: 104 RNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNL 163
R ++ L+L C+K+TD++ + +F +L+ L L+ +T++ L ++ GC +LE+L L
Sbjct: 75 RALQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLAL 133
Query: 164 SWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRI 221
S C +++ G L+ L L C+QL ++ L I C +L L++ +C I
Sbjct: 134 SHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGI 191
Score = 60.5 bits (145), Expect = 3e-09
Identities = 34/125 (27%), Positives = 67/125 (53%), Gaps = 1/125 (0%)
Query: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
L++L L C + D+SL Q + + L+L+ ++TD+ +++R C L+HL L+
Sbjct: 77 LQELDLTACSKLTDASLAKVLQFLQ-LRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135
Query: 140 CVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEA 199
C +++ + L++LNLS C Q+ + ++A+ + CR L+ L + C + A
Sbjct: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAA 195
Query: 200 LKHIQ 204
++ Q
Sbjct: 196 VRRFQ 200
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
sapiens]
Length = 1336
Score = 63.9 bits (154), Expect = 3e-10
Identities = 73/280 (26%), Positives = 118/280 (42%), Gaps = 54/280 (19%)
Query: 130 SKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLL 189
S L H DL C+ + CR N CD+ I+ + C+ + L+L
Sbjct: 1075 SYLSHQDLCVCMRV-----------CRTW---NRWCCDKRLWTRID--LNHCKSITPLML 1118
Query: 190 RGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTD 249
G + + VSL+L S + I+ + + + L+ L LSGCS +
Sbjct: 1119 SGIIRRQP-------------VSLDL-SWTNISKKQLSWLINRLPGLRDLVLSGCSWIAV 1164
Query: 250 ASLTALGLNCPRLQILEAARCSHLTDAGFTLLA-----------------RNCHELEKMD 292
++L + +CP L+ L+ L DA L RN EL
Sbjct: 1165 SALCSS--SCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAG 1222
Query: 293 LEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI-LHLSNSTCGHERLRVLELDNC 351
L+ ITD++L + H P L L LS+C +TD I L + T + L + L +C
Sbjct: 1223 LD----ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDC 1278
Query: 352 LLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQL 391
+TD L + C + ++L C+QVT+ G ++ A++
Sbjct: 1279 NKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEM 1318
Score = 54.7 bits (130), Expect = 2e-07
Identities = 56/251 (22%), Positives = 102/251 (40%), Gaps = 29/251 (11%)
Query: 17 KELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENISKRC 76
+E+ + +FS+L LC C ++ + WN D W RIDL N + ++ I +R
Sbjct: 1067 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRR- 1124
Query: 77 GGFLRKLSL-RGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHL 135
+ +SL + L + L L+GC+ I S S S C L+ L
Sbjct: 1125 ----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS--CPLLRTL 1178
Query: 136 DLTSCVSITNSSLKGI--------------SEGCRNLEYLNLSWCDQITKDGIEALVRGC 181
D+ + ++ ++ + RN+ L L+ D IT + ++R
Sbjct: 1179 DVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLIIRHM 1237
Query: 182 RGLKALLLRGCTQLEDEALKHI----QNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQ 237
L L L C + D+++ + L +NL C+++TD+ + + C +
Sbjct: 1238 PLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQ-CLSFFKRCGNIC 1296
Query: 238 ALCLSGCSNLT 248
+ L C +T
Sbjct: 1297 HIDLRYCKQVT 1307
Score = 30.0 bits (66), Expect = 4.1
Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTC 122
L +++L C V D L +F + C NI H++L C ++T C
Sbjct: 1270 LTEINLSDCNKVTDQCL-SFFKRCGNICHIDLRYCKQVTKEGC 1311
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
sapiens]
Length = 1265
Score = 63.9 bits (154), Expect = 3e-10
Identities = 73/280 (26%), Positives = 118/280 (42%), Gaps = 54/280 (19%)
Query: 130 SKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLL 189
S L H DL C+ + CR N CD+ I+ + C+ + L+L
Sbjct: 1006 SYLSHQDLCVCMRV-----------CRTW---NRWCCDKRLWTRID--LNHCKSITPLML 1049
Query: 190 RGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTD 249
G + + VSL+L S + I+ + + + L+ L LSGCS +
Sbjct: 1050 SGIIRRQP-------------VSLDL-SWTNISKKQLSWLINRLPGLRDLVLSGCSWIAV 1095
Query: 250 ASLTALGLNCPRLQILEAARCSHLTDAGFTLLA-----------------RNCHELEKMD 292
++L + +CP L+ L+ L DA L RN EL
Sbjct: 1096 SALCSS--SCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAG 1153
Query: 293 LEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI-LHLSNSTCGHERLRVLELDNC 351
L+ ITD++L + H P L L LS+C +TD I L + T + L + L +C
Sbjct: 1154 LD----ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDC 1209
Query: 352 LLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQL 391
+TD L + C + ++L C+QVT+ G ++ A++
Sbjct: 1210 NKVTDQCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEM 1249
Score = 54.7 bits (130), Expect = 2e-07
Identities = 56/251 (22%), Positives = 102/251 (40%), Gaps = 29/251 (11%)
Query: 17 KELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENISKRC 76
+E+ + +FS+L LC C ++ + WN D W RIDL N + ++ I +R
Sbjct: 998 REVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDL-NHCKSITPLMLSGIIRR- 1055
Query: 77 GGFLRKLSL-RGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHL 135
+ +SL + L + L L+GC+ I S S S C L+ L
Sbjct: 1056 ----QPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSALCSSS--CPLLRTL 1109
Query: 136 DLTSCVSITNSSLKGI--------------SEGCRNLEYLNLSWCDQITKDGIEALVRGC 181
D+ + ++ ++ + RN+ L L+ D IT + ++R
Sbjct: 1110 DVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRLIIRHM 1168
Query: 182 RGLKALLLRGCTQLEDEALKHI----QNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQ 237
L L L C + D+++ + L +NL C+++TD+ + + C +
Sbjct: 1169 PLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQ-CLSFFKRCGNIC 1227
Query: 238 ALCLSGCSNLT 248
+ L C +T
Sbjct: 1228 HIDLRYCKQVT 1238
Score = 31.2 bits (69), Expect = 1.9
Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 4/61 (6%)
Query: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
L +++L C V D L +F + C NI H++L C ++T C +F +++ S
Sbjct: 1201 LTEINLSDCNKVTDQCL-SFFKRCGNICHIDLRYCKQVTKEGC---EQFIAEMSSFQGRS 1256
Query: 140 C 140
C
Sbjct: 1257 C 1257
>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
sapiens]
Length = 539
Score = 62.0 bits (149), Expect = 1e-09
Identities = 101/417 (24%), Positives = 162/417 (38%), Gaps = 39/417 (9%)
Query: 14 KLPKELLLRIFSFL-----DIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQID--VEG 66
++P E+L++IF L + L R A++ + W A + W + L + + +G
Sbjct: 114 RIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
Query: 67 RV---------VENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKI 117
V +E + L++L+L LK + C + L L+GC +
Sbjct: 174 GVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGV 233
Query: 118 TDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEAL 177
T L++ C +L LDL + + + + + E + L L++ Q T L
Sbjct: 234 TADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALL 293
Query: 178 VRGCRGLKAL-LLRGCT------QLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQIC 230
C L+ L + G QL EAL+ L LNL + GV
Sbjct: 294 GSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAP-G 352
Query: 231 RGCHRLQALCL--SGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHEL 288
G L+ LCL S C+ +++ L L P L++L+ C+ +T AG L C EL
Sbjct: 353 PGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CREL 410
Query: 289 EKMDL------EECILITDSTLIQLSIHCPKLQALSLSHCELITDD----GILHLSNSTC 338
E++ L + L + + C L+ L LS D LS
Sbjct: 411 EQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGG 470
Query: 339 GHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395
H L L L + + +C GL L L C+ + R G+KR L V+
Sbjct: 471 SHPALCSLNLRGTRVTPSTVSSVISSCPGLLYLNLESCRCLPR-GLKRAYRGLEEVQ 526
>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
sapiens]
Length = 694
Score = 61.2 bits (147), Expect = 2e-09
Identities = 70/272 (25%), Positives = 113/272 (41%), Gaps = 25/272 (9%)
Query: 15 LPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENISK 74
LP+ LR+F L LC C ++ + W+ D W R+DL + + + ++ + +
Sbjct: 424 LPRAAWLRVFQHLGPRELCICMRVCRTWSRWCYDKRLWPRMDL-SRRKSLTPPMLSGVVR 482
Query: 75 RCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKH 134
R R L L GV L + ++ L L+GC+ ++ S S L+
Sbjct: 483 RQP---RALDL-SWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSVSALGSAP--LPALRL 536
Query: 135 LDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQ 194
LDL + +S L+ L TK G +G+ L L G +
Sbjct: 537 LDLRWIEDVKDSQLR------------ELLLPPPDTKPGQTESRGRLQGVAELRLAG-LE 583
Query: 195 LEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQA----LCLSGCSNLTDA 250
L D +L+ + + +L +L+L C+ + D V + L+ L L+GC LTD
Sbjct: 584 LTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTSPLRETLVHLNLAGCHRLTDH 643
Query: 251 SLTALGLNCPRLQILEAARCSHLTDAGFTLLA 282
L L CPRL+ L+ C L+ LA
Sbjct: 644 CL-PLFRRCPRLRRLDLRSCRQLSPEACARLA 674
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/175 (30%), Positives = 77/175 (44%), Gaps = 24/175 (13%)
Query: 236 LQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLA------------- 282
LQ L LSGCS L+ ++L + L P L++L+ + D+ L
Sbjct: 510 LQELVLSGCSWLSVSALGSAPL--PALRLLDLRWIEDVKDSQLRELLLPPPDTKPGQTES 567
Query: 283 ----RNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTC 338
+ EL LE +TD++L L H P+L AL LSHC + D + L+ T
Sbjct: 568 RGRLQGVAELRLAGLE----LTDASLRLLLRHAPQLSALDLSHCAHVGDPSVHLLTAPTS 623
Query: 339 G-HERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQLP 392
E L L L C +TD L C L RL+L C+Q++ R+ A P
Sbjct: 624 PLRETLVHLNLAGCHRLTDHCLPLFRRCPRLRRLDLRSCRQLSPEACARLAAAGP 678
>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
sapiens]
Length = 533
Score = 58.9 bits (141), Expect = 8e-09
Identities = 97/411 (23%), Positives = 157/411 (38%), Gaps = 33/411 (8%)
Query: 14 KLPKELLLRIFSFL-----DIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRV 68
++P E+L++IF L + L R A++ + W A + W + L + + +
Sbjct: 114 RIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
Query: 69 VENISKRCGGFLRKLSLRGCIGVGDSSL-----KTFAQNCRNIEHLNLNGCTKITDSTCY 123
K+ L L + +L + + C + L L+GC +T
Sbjct: 174 GVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQLVGECCPRLTFLKLSGCHGVTADALV 233
Query: 124 SLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRG 183
L++ C +L LDL + + + + + E + L L++ Q T L C
Sbjct: 234 MLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQ 293
Query: 184 LKAL-LLRGCT------QLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRL 236
L+ L + G QL EAL+ L LNL + GV G L
Sbjct: 294 LQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAP-GPGFPSL 352
Query: 237 QALCL--SGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDL- 293
+ LCL S C+ +++ L L P L++L+ C+ +T AG L C ELE++ L
Sbjct: 353 EELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CRELEQLHLG 410
Query: 294 -----EECILITDSTLIQLSIHCPKLQALSLSHCELITDD----GILHLSNSTCGHERLR 344
+ L + + C L+ L LS D LS H L
Sbjct: 411 LYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALC 470
Query: 345 VLELDNCLLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395
L L + + +C GL L L C+ + R G+KR L V+
Sbjct: 471 SLNLRGTRVTPSTVSSVISSCPGLLYLNLESCRCLPR-GLKRAYRGLEEVQ 520
>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
sapiens]
Length = 565
Score = 57.4 bits (137), Expect = 2e-08
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 62/199 (31%)
Query: 15 LPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGS--------NWQRIDLFN---FQID 63
LP E++L IFS+L+ LCRC+Q+S W+ L GS +W R D ++ ++D
Sbjct: 82 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 141
Query: 64 VEGR------------------------------------------------VVENISKR 75
E ++ N+
Sbjct: 142 TEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVLPY 201
Query: 76 CGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRF--CSKLK 133
G ++ L L V ++ + C N+EHL+L T I+DS S S C L+
Sbjct: 202 VGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ-TDISDSAFDSWSWLGCCQSLR 260
Query: 134 HLDLTSCVSITNSSLKGIS 152
HLDL+ C IT+ +L+ IS
Sbjct: 261 HLDLSGCEKITDVALEKIS 279
Score = 43.1 bits (100), Expect = 5e-04
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 70 ENISKRCGGFLRKLSLRGCIGVGDSSLK--TFAQNCRNIEHLNLNGCTKITDSTCYSLSR 127
E + G L LSL GC + D L+ T +EHLNL+GC IT + L
Sbjct: 464 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 523
Query: 128 FCSKLKHLDLTSCVSITNSSLKGISEGCRNLE 159
C L C +I N + GC+NL+
Sbjct: 524 ACPSLNDEYFYYCDNI-NGPHADTASGCQNLQ 554
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 3/93 (3%)
Query: 95 SLKTFAQNCRNIEHLNLNGCTKITDS--TCYSLSRFCSKLKHLDLTSCVSITNSSLKGIS 152
S K+ + R + L+L+GC +ITD +L L+HL+L+ C++IT + L+ +
Sbjct: 463 SEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLV 522
Query: 153 EGCRNLEYLNLSWCDQITKDGIEALVRGCRGLK 185
C +L +CD I + GC+ L+
Sbjct: 523 SACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 554
Score = 36.6 bits (83), Expect = 0.044
Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 210 LVSLNLQSCSRITDEG--VVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRL 262
L+ L+L C +ITD G V+ + G L+ L LSGC +T A L L CP L
Sbjct: 474 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 528
Score = 32.3 bits (72), Expect = 0.83
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 311 CPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGL 368
CP L+ L L+ + I+D S C + LR L+L C ITDVALE + G+
Sbjct: 229 CPNLEHLDLTQTD-ISDSAFDSWSWLGCC-QSLRHLDLSGCEKITDVALEKISRALGI 284
Score = 32.0 bits (71), Expect = 1.1
Identities = 12/25 (48%), Positives = 18/25 (72%)
Query: 103 CRNIEHLNLNGCTKITDSTCYSLSR 127
C+++ HL+L+GC KITD +SR
Sbjct: 256 CQSLRHLDLSGCEKITDVALEKISR 280
Score = 30.4 bits (67), Expect = 3.2
Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 5/83 (6%)
Query: 262 LQILEAARCSHLTDAGFTLLARN--CHELEKMDLEECILITDSTLIQLSIHCPKLQALSL 319
L L + C +TD G +L LE ++L C+ IT + L L CP L
Sbjct: 474 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 533
Query: 320 SHCELITD---DGILHLSNSTCG 339
+C+ I D N CG
Sbjct: 534 YYCDNINGPHADTASGCQNLQCG 556
Score = 30.0 bits (66), Expect = 4.1
Identities = 37/125 (29%), Positives = 43/125 (34%), Gaps = 27/125 (21%)
Query: 147 SLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNY 206
S K E R L +L+LS C QIT G+ L G G LE
Sbjct: 463 SEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLG---------GGLPYLEH--------- 504
Query: 207 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASL-TALGLNCPRLQIL 265
LNL C IT G+ + C L C N+ TA G C LQ
Sbjct: 505 ------LNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASG--CQNLQCG 556
Query: 266 EAARC 270
A C
Sbjct: 557 FRACC 561
>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
sapiens]
Length = 691
Score = 57.4 bits (137), Expect = 2e-08
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 62/199 (31%)
Query: 15 LPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGS--------NWQRIDLFN---FQID 63
LP E++L IFS+L+ LCRC+Q+S W+ L GS +W R D ++ ++D
Sbjct: 208 LPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATELD 267
Query: 64 VEGR------------------------------------------------VVENISKR 75
E ++ N+
Sbjct: 268 TEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVLPY 327
Query: 76 CGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRF--CSKLK 133
G ++ L L V ++ + C N+EHL+L T I+DS S S C L+
Sbjct: 328 VGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQ-TDISDSAFDSWSWLGCCQSLR 386
Query: 134 HLDLTSCVSITNSSLKGIS 152
HLDL+ C IT+ +L+ IS
Sbjct: 387 HLDLSGCEKITDVALEKIS 405
Score = 43.1 bits (100), Expect = 5e-04
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 70 ENISKRCGGFLRKLSLRGCIGVGDSSLK--TFAQNCRNIEHLNLNGCTKITDSTCYSLSR 127
E + G L LSL GC + D L+ T +EHLNL+GC IT + L
Sbjct: 590 EKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVS 649
Query: 128 FCSKLKHLDLTSCVSITNSSLKGISEGCRNLE 159
C L C +I N + GC+NL+
Sbjct: 650 ACPSLNDEYFYYCDNI-NGPHADTASGCQNLQ 680
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 3/93 (3%)
Query: 95 SLKTFAQNCRNIEHLNLNGCTKITDS--TCYSLSRFCSKLKHLDLTSCVSITNSSLKGIS 152
S K+ + R + L+L+GC +ITD +L L+HL+L+ C++IT + L+ +
Sbjct: 589 SEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLV 648
Query: 153 EGCRNLEYLNLSWCDQITKDGIEALVRGCRGLK 185
C +L +CD I + GC+ L+
Sbjct: 649 SACPSLNDEYFYYCDNINGPHADT-ASGCQNLQ 680
Score = 36.6 bits (83), Expect = 0.044
Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 210 LVSLNLQSCSRITDEG--VVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRL 262
L+ L+L C +ITD G V+ + G L+ L LSGC +T A L L CP L
Sbjct: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSL 654
Score = 32.3 bits (72), Expect = 0.83
Identities = 22/58 (37%), Positives = 30/58 (51%), Gaps = 2/58 (3%)
Query: 311 CPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGL 368
CP L+ L L+ + I+D S C + LR L+L C ITDVALE + G+
Sbjct: 355 CPNLEHLDLTQTD-ISDSAFDSWSWLGCC-QSLRHLDLSGCEKITDVALEKISRALGI 410
Score = 32.0 bits (71), Expect = 1.1
Identities = 12/25 (48%), Positives = 18/25 (72%)
Query: 103 CRNIEHLNLNGCTKITDSTCYSLSR 127
C+++ HL+L+GC KITD +SR
Sbjct: 382 CQSLRHLDLSGCEKITDVALEKISR 406
Score = 30.4 bits (67), Expect = 3.2
Identities = 24/83 (28%), Positives = 33/83 (39%), Gaps = 5/83 (6%)
Query: 262 LQILEAARCSHLTDAGFTLLARN--CHELEKMDLEECILITDSTLIQLSIHCPKLQALSL 319
L L + C +TD G +L LE ++L C+ IT + L L CP L
Sbjct: 600 LLFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYF 659
Query: 320 SHCELITD---DGILHLSNSTCG 339
+C+ I D N CG
Sbjct: 660 YYCDNINGPHADTASGCQNLQCG 682
Score = 30.0 bits (66), Expect = 4.1
Identities = 37/125 (29%), Positives = 43/125 (34%), Gaps = 27/125 (21%)
Query: 147 SLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNY 206
S K E R L +L+LS C QIT G+ L G G LE
Sbjct: 589 SEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLG---------GGLPYLEH--------- 630
Query: 207 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASL-TALGLNCPRLQIL 265
LNL C IT G+ + C L C N+ TA G C LQ
Sbjct: 631 ------LNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASG--CQNLQCG 682
Query: 266 EAARC 270
A C
Sbjct: 683 FRACC 687
>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
Length = 1162
Score = 57.0 bits (136), Expect = 3e-08
Identities = 68/261 (26%), Positives = 103/261 (39%), Gaps = 53/261 (20%)
Query: 135 LDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQ 194
+DL+ C +I +L GI + R L+LSW + I+K + LV GLK LLL GC+
Sbjct: 933 IDLSRCKAIVPQALSGIIK--RQPVSLDLSWTN-ISKKQLTWLVNRLPGLKDLLLAGCSW 989
Query: 195 LEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLT- 253
+ AL S C L L
Sbjct: 990 ---------------------------------------SAVSALSTSSCPLLRTLDLRW 1010
Query: 254 ALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPK 313
A+G+ P+++ L + L RN + L+ ITD+TL + H P
Sbjct: 1011 AVGIKDPQIRDLLTPPADKPGQDNRSKL-RNMTDFRLAGLD----ITDATLRLIIRHMPL 1065
Query: 314 LQALSLSHCELITDDG---ILHLSNSTCGHERLRVLELDNCLLITDVALEHLENCRGLER 370
L L LSHC +TD + + +ST L L + C +TD L +L +
Sbjct: 1066 LSRLDLSHCSHLTDQSSNLLTAVGSST--RYSLTELNMAGCNKLTDQTLIYLRRIANVTL 1123
Query: 371 LELYDCQQVTRAGIKRMRAQL 391
++L C+Q+TR + + L
Sbjct: 1124 IDLRGCKQITRKACEHFISDL 1144
Score = 55.5 bits (132), Expect = 9e-08
Identities = 63/275 (22%), Positives = 105/275 (38%), Gaps = 69/275 (25%)
Query: 15 LPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVV----- 69
+ +E+ + +F +L LC C ++ K W D W +IDL + V +
Sbjct: 893 MQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKR 952
Query: 70 ---------ENISKR-------------------CG------------GFLRKLSLRGCI 89
NISK+ C LR L LR +
Sbjct: 953 QPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAV 1012
Query: 90 GVGDSSLKTF------------AQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDL 137
G+ D ++ RN+ L G ITD+T + R L LDL
Sbjct: 1013 GIKDPQIRDLLTPPADKPGQDNRSKLRNMTDFRLAG-LDITDATLRLIIRHMPLLSRLDL 1071
Query: 138 TSCVSITNSS---LKGISEGCR-NLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCT 193
+ C +T+ S L + R +L LN++ C+++T D +R + + LRGC
Sbjct: 1072 SHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLT-DQTLIYLRRIANVTLIDLRGCK 1130
Query: 194 QLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQ 228
Q+ +A +H + L++ S ++DE ++Q
Sbjct: 1131 QITRKACEHF------ISDLSINSLYCLSDEKLIQ 1159
>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]
Length = 326
Score = 56.6 bits (135), Expect = 4e-08
Identities = 65/296 (21%), Positives = 123/296 (41%), Gaps = 56/296 (18%)
Query: 14 KLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQIDVEGRVVENIS 73
+LP +LL IFS+L + R +++ W L D W+ +DL + + +V+ ++
Sbjct: 6 ELPDSVLLEIFSYLPVRDRIRISRVCHRWKRLVDDRWLWRHVDLTLY--TMRPKVMWHLL 63
Query: 74 KR-CGGFLRKLSLRGCIGVGDSS-------LKTFAQNCRNIEHLNLNGCTKITDSTCYSL 125
+R L L + G + G + L+ Q C N++ L C + D + +
Sbjct: 64 RRYMASRLHSLRMGGYLFSGSQAPQLSPALLRALGQKCPNLKRL----CLHVADLSMVPI 119
Query: 126 SRFCSKLKHLDLTSC---------------------------VSITNSSLKGISEGCRNL 158
+ S L+ L+L SC + + L+G++ R L
Sbjct: 120 TSLPSTLRTLELHSCEISMAWLHKQQDPTVLPLLECIVLDRVPAFRDEHLQGLTR-FRAL 178
Query: 159 EYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSC 218
L L ++T+ G++A ++ L+ L + GCT D L I + ++ +
Sbjct: 179 RSLVLGGTYRVTETGLDAGLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKI----- 233
Query: 219 SRITDEGV----VQICRGCHRLQALCLSG----CSNLTDASLTALGLNCPRLQILE 266
R+T G+ + + G L++LCL G + + + L P+L++LE
Sbjct: 234 -RLTVRGLSAPGLAVLEGMPALESLCLQGPLVTPEMPSPTEILSSCLTMPKLRVLE 288
Score = 30.4 bits (67), Expect = 3.2
Identities = 37/164 (22%), Positives = 66/164 (40%), Gaps = 18/164 (10%)
Query: 164 SWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCS---- 219
S Q++ + AL + C LK L C + D ++ I + L +L L SC
Sbjct: 84 SQAPQLSPALLRALGQKCPNLKRL----CLHVADLSMVPITSLPSTLRTLELHSCEISMA 139
Query: 220 ---RITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDA 276
+ D V+ + L+ + L D L L L+ L +T+
Sbjct: 140 WLHKQQDPTVLPL------LECIVLDRVPAFRDEHLQGL-TRFRALRSLVLGGTYRVTET 192
Query: 277 GFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLS 320
G + L+++++ C L DSTL+ +S H ++ + L+
Sbjct: 193 GLDAGLQELSYLQRLEVLGCTLSADSTLLAISRHLRDVRKIRLT 236
>gi|122937219 F-box protein 41 [Homo sapiens]
Length = 936
Score = 53.9 bits (128), Expect = 3e-07
Identities = 63/250 (25%), Positives = 103/250 (41%), Gaps = 30/250 (12%)
Query: 20 LLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQI-------------DVEG 66
L IF++LD TL A++ + W +A + W R+ L N ++
Sbjct: 618 LFCIFTYLDTRTLLHAAEVCRDWRFVARHPAVWTRVLLENARVCSKFLAMLAQWCTQAHS 677
Query: 67 RVVENISKRCGGFLRK-----LSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKI-TDS 120
++N+ R G S RGC+ G SL A N+ L ++ C I TD
Sbjct: 678 LTLQNLKPRQRGKKESKEEYARSTRGCLEAGLESLLKAAGG--NLLILRISHCPNILTDR 735
Query: 121 TCYSLSRFCSKLKHLDLTSCVS-ITNSSLKGISEGCR---NLEYLNLSWCDQITKDG--- 173
+ + S +C L+ + S + + + + GCR +L+ L C Q T+
Sbjct: 736 SLWLASCYCRALQAVTYRSATDPVGHEVIWALGAGCREIVSLQVAPLHPCQQPTRFSNRC 795
Query: 174 IEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQICR-G 232
++ + R L+AL + G + L + C L L L S IT E ++CR G
Sbjct: 796 LQMIGRCWPHLRALGVGG-AGCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREG 854
Query: 233 CHRLQALCLS 242
L+ L L+
Sbjct: 855 LKGLEMLVLT 864
Score = 37.0 bits (84), Expect = 0.034
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 1/85 (1%)
Query: 75 RCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKH 134
RC LR L + G G G L + A+NC ++ L L+ ++IT + R K
Sbjct: 801 RCWPHLRALGVGGA-GCGVQGLASLARNCMRLQVLELDHVSEITQEVAAEVCREGLKGLE 859
Query: 135 LDLTSCVSITNSSLKGISEGCRNLE 159
+ + + +T +L + CRNL+
Sbjct: 860 MLVLTATPVTPKALLHFNSICRNLK 884
>gi|30795121 F-box and WD repeat domain containing 8 isoform 2
[Homo sapiens]
Length = 532
Score = 47.8 bits (112), Expect = 2e-05
Identities = 22/50 (44%), Positives = 30/50 (60%)
Query: 6 NDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRI 55
ND + +LP EL + IF +LD L RCAQ+SK W ++A D W R+
Sbjct: 44 NDVPFFDIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRL 93
>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
sapiens]
Length = 598
Score = 47.8 bits (112), Expect = 2e-05
Identities = 22/50 (44%), Positives = 30/50 (60%)
Query: 6 NDEGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRI 55
ND + +LP EL + IF +LD L RCAQ+SK W ++A D W R+
Sbjct: 110 NDVPFFDIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRL 159
>gi|27312027 F-box only protein 16 [Homo sapiens]
Length = 292
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/51 (49%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Query: 14 KLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDL-FNFQID 63
KLP+ L L IFSFLD +LCRCAQ+ W LA W L FN+ I+
Sbjct: 91 KLPRVLSLYIFSFLDPRSLCRCAQVCWHWKNLAELDQLWMLKCLRFNWYIN 141
>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
Length = 843
Score = 40.0 bits (92), Expect = 0.004
Identities = 21/54 (38%), Positives = 34/54 (62%)
Query: 8 EGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQ 61
E + +KLP E++L+IFS+L LCR A + K ++ LA D W+R+ + F+
Sbjct: 68 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFE 121
>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
Length = 686
Score = 40.0 bits (92), Expect = 0.004
Identities = 21/54 (38%), Positives = 34/54 (62%)
Query: 8 EGLINKKLPKELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQ 61
E + +KLP E++L+IFS+L LCR A + K ++ LA D W+R+ + F+
Sbjct: 68 EQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFE 121
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,810,287
Number of Sequences: 37866
Number of extensions: 666945
Number of successful extensions: 2542
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 1901
Number of HSP's gapped (non-prelim): 219
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.