Guide to the Human Genome
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Search of human proteins with 15834617

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15834617 excision repair cross-complementing rodent repair
deficiency, complementation group 2 protein isoform 1 [Homo sapiens]
         (760 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15834617 excision repair cross-complementing rodent repair de...  1514   0.0  
gi|195947407 excision repair cross-complementing rodent repair d...   778   0.0  
gi|91984775 regulator of telomere elongation helicase 1 isoform ...   202   9e-52
gi|7706541 regulator of telomere elongation helicase 1 isoform 1...   202   9e-52
gi|14042978 BRCA1 interacting protein C-terminal helicase 1 [Hom...   171   2e-42
gi|100913202 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso...   166   6e-41
gi|132566527 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso...   140   3e-33
gi|212549538 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 [Ho...   124   2e-28
gi|100913204 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso...   113   7e-25
gi|239755744 PREDICTED: similar to Putative ATP-dependent RNA he...   107   3e-23
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]           33   1.3  
gi|63055049 phosphoglucomutase 2 [Homo sapiens]                        32   1.7  
gi|51702248 G protein-coupled receptor associated sorting protei...    32   2.2  
gi|19923967 G protein-coupled receptor associated sorting protei...    32   2.2  
gi|4759336 Fanconi anemia, complementation group G [Homo sapiens]      31   3.7  
gi|110349767 calcium channel, voltage-dependent, L type, alpha 1...    31   4.9  
gi|88196790 coiled-coil domain containing 88 [Homo sapiens]            31   4.9  
gi|91598777 transmembrane protein 146 [Homo sapiens]                   30   6.4  
gi|162287219 prune homolog 2 [Homo sapiens]                            30   8.3  
gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens]    30   8.3  

>gi|15834617 excision repair cross-complementing rodent repair
           deficiency, complementation group 2 protein isoform 1
           [Homo sapiens]
          Length = 760

 Score = 1514 bits (3919), Expect = 0.0
 Identities = 760/760 (100%), Positives = 760/760 (100%)

Query: 1   MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ 60
           MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ
Sbjct: 1   MKLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQ 60

Query: 61  RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE 120
           RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE
Sbjct: 61  RAYPLEVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPE 120

Query: 121 VTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDL 180
           VTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDL
Sbjct: 121 VTPLRFGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDL 180

Query: 181 KALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID 240
           KALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID
Sbjct: 181 KALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID 240

Query: 241 NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARE 300
           NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARE
Sbjct: 241 NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARE 300

Query: 301 TDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSG 360
           TDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSG
Sbjct: 301 TDAHLANPVLPDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSG 360

Query: 361 LAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEP 420
           LAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEP
Sbjct: 361 LAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLVSTYAKGFTIIIEP 420

Query: 421 FDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMAT 480
           FDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMAT
Sbjct: 421 FDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIYPKILDFHPVTMAT 480

Query: 481 FTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFT 540
           FTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFT
Sbjct: 481 FTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFT 540

Query: 541 SYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVA 600
           SYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVA
Sbjct: 541 SYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKYQEACENGRGAILLSVA 600

Query: 601 RGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHA 660
           RGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHA
Sbjct: 601 RGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRDQFQIRENDFLTFDAMRHA 660

Query: 661 AQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYF 720
           AQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYF
Sbjct: 661 AQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYF 720

Query: 721 LRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL 760
           LRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL
Sbjct: 721 LRQMAQPFHREDQLGLSLLSLEQLESEETLKRIEQIAQQL 760


>gi|195947407 excision repair cross-complementing rodent repair
           deficiency, complementation group 2 protein isoform 2
           [Homo sapiens]
          Length = 405

 Score =  778 bits (2010), Expect = 0.0
 Identities = 389/389 (100%), Positives = 389/389 (100%)

Query: 25  MRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVI 84
           MRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVI
Sbjct: 1   MRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAYPLEVTKLIYCSRTVPEIEKVI 60

Query: 85  EELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRA 144
           EELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRA
Sbjct: 61  EELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYVRA 120

Query: 145 QYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANV 204
           QYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANV
Sbjct: 121 QYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANV 180

Query: 205 VVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLE 264
           VVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLE
Sbjct: 181 VVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGNLE 240

Query: 265 TLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIR 324
           TLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIR
Sbjct: 241 TLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPGSIR 300

Query: 325 TAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLH 384
           TAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLH
Sbjct: 301 TAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLH 360

Query: 385 TLEITDLADFSPLTLLANFATLVSTYAKG 413
           TLEITDLADFSPLTLLANFATLVSTYAKG
Sbjct: 361 TLEITDLADFSPLTLLANFATLVSTYAKG 389


>gi|91984775 regulator of telomere elongation helicase 1 isoform 2
           [Homo sapiens]
          Length = 1300

 Score =  202 bits (514), Expect = 9e-52
 Identities = 197/775 (25%), Positives = 325/775 (41%), Gaps = 120/775 (15%)

Query: 2   KLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQR 61
           K+ ++G+ V FP+   Y  Q  YM ++   L  K +G+LE P+GTGKT+ LL   +A++ 
Sbjct: 3   KIVLNGVTVDFPFQP-YKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWRE 61

Query: 62  ---------------------------------------AYPLEVTKLIYCSRTVPEIEK 82
                                                  A   ++ K+IY SRT  ++ +
Sbjct: 62  HLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQ 121

Query: 83  VIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYV 142
           VI ELR            K+  LG    SR+ LCIHPEV            C    AS  
Sbjct: 122 VINELRNT------SYRPKVCVLG----SREQLCIHPEVKKQESNHLQIHLCRKKVASR- 170

Query: 143 RAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHA 202
                       C FY   +    E  L + I +++DL   G +   CPY+L+R     A
Sbjct: 171 -----------SCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQA 219

Query: 203 NVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGN 262
           +++   Y+YLLD K     + +L +  VV+FDEAHN++ +C +S S +LT   L      
Sbjct: 220 DIIFMPYNYLLDAKSRRAHNIDL-KGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDV 278

Query: 263 LETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAV--P 320
           ++ + +   +  +  E            GL   +   E  A L   +L  E   +AV  P
Sbjct: 279 IDQVLEEQTKAAQQGEPHPEFSADSPSPGL---NMELEDIAKLKMILLRLEGAIDAVELP 335

Query: 321 GSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLR 380
           G          ++  L    +   + +  + +S    +  LA R  +         ++L 
Sbjct: 336 GDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGL--QKLA 393

Query: 381 SLLHTLEITDLADFSP-----LTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANP---I 432
            ++  +   D ++ SP     L  L ++   +   A G     +  D  + T A     +
Sbjct: 394 DIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDA-GHRRTAQRSDAWSTTAARKRGKV 452

Query: 433 LHFSCMDASLAIKPVFER-FQSVIITSGTLSPLDIY--------------PKILDFHPVT 477
           L + C     ++  +  +  +S+I+TSGTL+P+  +              P I+D H + 
Sbjct: 453 LSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIW 512

Query: 478 MATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVA 537
           +               ++ RG D   +SS F+ R     + + G  L  ++ VVP G++ 
Sbjct: 513 VG--------------VVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLI 558

Query: 538 FFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKY--QEACENGRGAI 595
           FF SY  ME ++  W  + +   ++  K LF+E +     S  +  Y  + A     GA 
Sbjct: 559 FFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGAT 618

Query: 596 LLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRD---------QFQI 646
            L+V RGK SEG+DF    GR VI+ G+PY       +  ++++L +         QF +
Sbjct: 619 FLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQF-L 677

Query: 647 RENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHL 701
              ++    A R   Q +GR IR + DYG +   D RFA  D R +LP W++ H+
Sbjct: 678 SGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHV 732


>gi|7706541 regulator of telomere elongation helicase 1 isoform 1
           [Homo sapiens]
          Length = 1219

 Score =  202 bits (514), Expect = 9e-52
 Identities = 197/775 (25%), Positives = 325/775 (41%), Gaps = 120/775 (15%)

Query: 2   KLNVDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQR 61
           K+ ++G+ V FP+   Y  Q  YM ++   L  K +G+LE P+GTGKT+ LL   +A++ 
Sbjct: 3   KIVLNGVTVDFPFQP-YKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWRE 61

Query: 62  ---------------------------------------AYPLEVTKLIYCSRTVPEIEK 82
                                                  A   ++ K+IY SRT  ++ +
Sbjct: 62  HLRDGISARKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQ 121

Query: 83  VIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRFGKDVDGKCHSLTASYV 142
           VI ELR            K+  LG    SR+ LCIHPEV            C    AS  
Sbjct: 122 VINELRNT------SYRPKVCVLG----SREQLCIHPEVKKQESNHLQIHLCRKKVASR- 170

Query: 143 RAQYQHDTSLPHCRFYEEFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHA 202
                       C FY   +    E  L + I +++DL   G +   CPY+L+R     A
Sbjct: 171 -----------SCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQA 219

Query: 203 NVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNIDNVCIDSMSVNLTRRTLDRCQGN 262
           +++   Y+YLLD K     + +L +  VV+FDEAHN++ +C +S S +LT   L      
Sbjct: 220 DIIFMPYNYLLDAKSRRAHNIDL-KGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDV 278

Query: 263 LETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAV--P 320
           ++ + +   +  +  E            GL   +   E  A L   +L  E   +AV  P
Sbjct: 279 IDQVLEEQTKAAQQGEPHPEFSADSPSPGL---NMELEDIAKLKMILLRLEGAIDAVELP 335

Query: 321 GSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLR 380
           G          ++  L    +   + +  + +S    +  LA R  +         ++L 
Sbjct: 336 GDDSGVTKPGSYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGL--QKLA 393

Query: 381 SLLHTLEITDLADFSP-----LTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANP---I 432
            ++  +   D ++ SP     L  L ++   +   A G     +  D  + T A     +
Sbjct: 394 DIIQIVFSVDPSEGSPGSPAGLGALQSYKVHIHPDA-GHRRTAQRSDAWSTTAARKRGKV 452

Query: 433 LHFSCMDASLAIKPVFER-FQSVIITSGTLSPLDIY--------------PKILDFHPVT 477
           L + C     ++  +  +  +S+I+TSGTL+P+  +              P I+D H + 
Sbjct: 453 LSYWCFSPGHSMHELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIW 512

Query: 478 MATFTMTLARVCLCPMIIGRGNDQVAISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVA 537
           +               ++ RG D   +SS F+ R     + + G  L  ++ VVP G++ 
Sbjct: 513 VG--------------VVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVVPYGLLI 558

Query: 538 FFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVALEKY--QEACENGRGAI 595
           FF SY  ME ++  W  + +   ++  K LF+E +     S  +  Y  + A     GA 
Sbjct: 559 FFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGAT 618

Query: 596 LLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKARLEYLRD---------QFQI 646
            L+V RGK SEG+DF    GR VI+ G+PY       +  ++++L +         QF +
Sbjct: 619 FLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQF-L 677

Query: 647 RENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKRGKLPRWIQEHL 701
              ++    A R   Q +GR IR + DYG +   D RFA  D R +LP W++ H+
Sbjct: 678 SGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHV 732


>gi|14042978 BRCA1 interacting protein C-terminal helicase 1 [Homo
           sapiens]
          Length = 1249

 Score =  171 bits (433), Expect = 2e-42
 Identities = 170/671 (25%), Positives = 292/671 (43%), Gaps = 79/671 (11%)

Query: 66  EVTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLR 125
           ++ K+ + +RT  +I ++  ELR+         G  +  L    SSR + C+HPEV    
Sbjct: 242 KIPKIYFGTRTHKQIAQITRELRRTA-----YSGVPMTIL----SSRDHTCVHPEVVG-N 291

Query: 126 FGKDVDGKCHSLTASYVRAQYQHDTSLPHCRFYEEFDAHGREVPLP-----AGIYNLDDL 180
           F +  + KC  L             +   C FY        +  L         +++++L
Sbjct: 292 FNR--NEKCMELL---------DGKNGKSCYFYHGVHKISDQHTLQTFQGMCKAWDIEEL 340

Query: 181 KALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAHNID 240
            +LG++   CPY+ AR  I  A+++   Y+YLLD +I + +   L ++ VV+ DEAHNI+
Sbjct: 341 VSLGKKLKACPYYTARELIQDADIIFCPYNYLLDAQIRESMDLNL-KEQVVILDEAHNIE 399

Query: 241 NVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLR-EASAAR 299
           +   +S S ++T   L   +  L+++      I++ D + LR     L+  L   A    
Sbjct: 400 DCARESASYSVTEVQLRFARDELDSMVNN--NIRKKDHEPLRAVCCSLINWLEANAEYLV 457

Query: 300 ETDAHLANPVLP-DEVLQEAVPGSIRTAE------HFLGFLRRLLE----YVKWRLRVQH 348
           E D   A  +   +E+L       I TA       HF   L++  +    Y K   R   
Sbjct: 458 ERDYESACKIWSGNEMLLTLHKMGITTATFPILQGHFSAVLQKEEKISPIYGKEEAREVP 517

Query: 349 VVQESPPAFLSGLAQRV-CIQRKPLRFCAERLRSLLHTLEITDLADFSPLTLLANFATLV 407
           V+  S    L GL   +  + R+  RF  +   ++  T   T+  D S            
Sbjct: 518 VISASTQIMLKGLFMVLDYLFRQNSRFADDYKIAIQQTYSWTNQIDISD----------- 566

Query: 408 STYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITSGTLSPLDIY 467
                G  ++ +         A  +L+F C++ ++A   +  + Q++++TSGTLSP+  +
Sbjct: 567 ---KNGLLVLPKNKKRSRQKTAVHVLNFWCLNPAVAFSDINGKVQTIVLTSGTLSPMKSF 623

Query: 468 PKILDFHPVTMATFTMTLARVCLCPM------IIGRGNDQVAISSKFETREDIAVIRNYG 521
              L        TFT+ L    +          IG G     + + F+  E        G
Sbjct: 624 SSELG------VTFTIQLEANHIIKNSQVWVGTIGSGPKGRNLCATFQNTETFEFQDEVG 677

Query: 522 NLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSV-- 579
            LLL +   V  GI+ F  SY+ +E     W   G+  N++  K + +E Q G +T+   
Sbjct: 678 ALLLSVCQTVSQGILCFLPSYKLLEKLKERWLSTGLWHNLELVKTVIVEPQGGEKTNFDE 737

Query: 580 ALEKYQEACE---NGRGAILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRILKAR 636
            L+ Y +A +      GA+L++V RGKVSEG+DF     RAVI  G+P+   +   ++ +
Sbjct: 738 LLQVYYDAIKYKGEKDGALLVAVCRGKVSEGLDFSDDNARAVITIGIPFPNVKDLQVELK 797

Query: 637 LEYLRDQFQIR----ENDFLTFDAMRHAAQCVGRAIRGKTDYGLMVFADKRFARGDKR-- 690
            +Y     ++R       +    A R   Q +GR IR + D+G ++  D RF     R  
Sbjct: 798 RQYNDHHSKLRGLLPGRQWYEIQAYRALNQALGRCIRHRNDWGALILVDDRFRNNPSRYI 857

Query: 691 GKLPRWIQEHL 701
             L +W+++ +
Sbjct: 858 SGLSKWVRQQI 868



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 23/58 (39%), Positives = 40/58 (68%), Gaps = 1/58 (1%)

Query: 5  VDGLLVYFPYDYIYPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRA 62
          + G+ +YFPY   YP Q + M  + R L++K H +LE P+G+GK+++LL   +A+Q++
Sbjct: 10 IGGVKIYFPYK-AYPSQLAMMNSILRGLNSKQHCLLESPTGSGKSLALLCSALAWQQS 66


>gi|100913202 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
           isoform 1 [Homo sapiens]
          Length = 906

 Score =  166 bits (421), Expect = 6e-41
 Identities = 174/718 (24%), Positives = 306/718 (42%), Gaps = 95/718 (13%)

Query: 67  VTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRF 126
           +TK+ YCSRT  ++ + + E++K         G+ +  +  +L SR+NLC++ +V  L  
Sbjct: 226 ITKIYYCSRTHSQLAQFVHEVKK------SPFGKDVRLV--SLGSRQNLCVNEDVKSLGS 277

Query: 127 GKDVDGKCHSLTASYVRAQYQHDTSLPH---------CRFYEEFDAHGREVPLPAGIYNL 177
            + ++ +C  +  S    +   +   P          C FY             A + ++
Sbjct: 278 VQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDM 337

Query: 178 DDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAH 237
           + L ALG+    CPY+ +R +I  A +VV  Y  LL           L +  VV+ DEAH
Sbjct: 338 EQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRL-QDQVVIIDEAH 396

Query: 238 NIDNVCIDSMSVNLTRRTLDRCQGN---LETLQKTVLRIKETDEQRLR------DEYRRL 288
           N+ +      SV ++   L  CQ +   L+ +++   R+K  +   L+      +++  +
Sbjct: 397 NLIDTITGMHSVEVSGSQL--CQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAV 454

Query: 289 VEGLREASAARETDAHLANPV--LPDEVLQEAVPG-SIRTAEHFL--GFLRRLLEYVKWR 343
           + G  + +   ++ +     +  + D + Q  +   ++   + +     + R L     R
Sbjct: 455 LGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTER 514

Query: 344 LRVQHVVQESPPA-----FLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLT 398
                  +E P       FL  L  R            E L +     + + L   SPL 
Sbjct: 515 YGAVFSSREQPKLAGFQQFLQSLQPRT----------TEALAAPADESQASTLRPASPLM 564

Query: 399 LLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITS 458
            +  F   ++T  +   +I+     R  +++   L F  ++ ++    V +  ++V+I  
Sbjct: 565 HIQGFLAALTTANQDGRVILS----RQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAG 620

Query: 459 GTLSPLDIYPKILDFHPVTMATFTMTLARVC------------LCPMIIGRGNDQVAISS 506
           GT+ P+       DF    +A   +   RV             + P++I  G     +  
Sbjct: 621 GTMQPVS------DFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGISNQPLEF 674

Query: 507 KFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKL 566
            F+ RE   ++   G +L  +  VVP G+V FF SY+Y+    A W + G+L  +   K 
Sbjct: 675 TFQKRELPQMMDEVGRILCNLCGVVPGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKK 734

Query: 567 LFIETQDGAETSVALEKYQ---EACENGR----GAILLSVARGKVSEGIDFVHHYGRAVI 619
           +F E +   +    L  Y    +AC   R    GA+LLSV  GK+SEGI+F  + GR V+
Sbjct: 735 IFQEPKSAHQVEQVLLAYSRCIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVV 794

Query: 620 MFGVPYVYTQSRILKARLEYL-----RDQFQIRENDFLTFD-AMRHAAQCVGRAIRGKTD 673
           M G+P+   +S  L+ ++ YL     R   Q      L  +  M+   Q +GRAIR + D
Sbjct: 795 MVGMPFPNIRSAELQEKMAYLDQTLPRAPGQAPPGKALVENLCMKAVNQSIGRAIRHQKD 854

Query: 674 YGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHRE 731
           +  +V  D+R+AR     KLP WI+     A + +    G  +A        Q FHRE
Sbjct: 855 FASVVLLDQRYARPPVLAKLPAWIR-----ARVEVKATFGPAIA------AVQKFHRE 901



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 20/55 (36%), Positives = 35/55 (63%), Gaps = 1/55 (1%)

Query: 10 VYFPYDYI-YPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAY 63
          ++FP+ +  Y  Q  +M EL R L+A   G+ E P+GTGK++SL+   +++ R +
Sbjct: 11 IHFPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWLRDF 65


>gi|132566527 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
           isoform 3 [Homo sapiens]
          Length = 970

 Score =  140 bits (354), Expect = 3e-33
 Identities = 145/621 (23%), Positives = 265/621 (42%), Gaps = 78/621 (12%)

Query: 67  VTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRF 126
           +TK+ YCSRT  ++ + + E++K         G+ +  +  +L SR+NLC++ +V  L  
Sbjct: 226 ITKIYYCSRTHSQLAQFVHEVKK------SPFGKDVRLV--SLGSRQNLCVNEDVKSLGS 277

Query: 127 GKDVDGKCHSLTASYVRAQYQHDTSLPH---------CRFYEEFDAHGREVPLPAGIYNL 177
            + ++ +C  +  S    +   +   P          C FY             A + ++
Sbjct: 278 VQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDM 337

Query: 178 DDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAH 237
           + L ALG+    CPY+ +R +I  A +VV  Y  LL           L +  VV+ DEAH
Sbjct: 338 EQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRL-QDQVVIIDEAH 396

Query: 238 NIDNVCIDSMSVNLTRRTLDRCQGN---LETLQKTVLRIKETDEQRLR------DEYRRL 288
           N+ +      SV ++   L  CQ +   L+ +++   R+K  +   L+      +++  +
Sbjct: 397 NLIDTITGMHSVEVSGSQL--CQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAV 454

Query: 289 VEGLREASAARETDAHLANPV--LPDEVLQEAVPG-SIRTAEHFL--GFLRRLLEYVKWR 343
           + G  + +   ++ +     +  + D + Q  +   ++   + +     + R L     R
Sbjct: 455 LGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTER 514

Query: 344 LRVQHVVQESPPA-----FLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLT 398
                  +E P       FL  L  R            E L +     + + L   SPL 
Sbjct: 515 YGAVFSSREQPKLAGFQQFLQSLQPRT----------TEALAAPADESQASTLRPASPLM 564

Query: 399 LLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITS 458
            +  F   ++T  +   +I+     R  +++   L F  ++ ++    V +  ++V+I  
Sbjct: 565 HIQGFLAALTTANQDGRVILS----RQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAG 620

Query: 459 GTLSPLDIYPKILDFHPVTMATFTMTLARVC------------LCPMIIGRGNDQVAISS 506
           GT+ P+       DF    +A   +   RV             + P++I  G     +  
Sbjct: 621 GTMQPVS------DFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGISNQPLEF 674

Query: 507 KFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKL 566
            F+ RE   ++   G +L  +  VVP G+V FF SY+Y+    A W + G+L  +   K 
Sbjct: 675 TFQKRELPQMMDEVGRILCNLCGVVPGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKK 734

Query: 567 LFIETQDGAETSVALEKYQ---EACENGR----GAILLSVARGKVSEGIDFVHHYGRAVI 619
           +F E +   +    L  Y    +AC   R    GA+LLSV  GK+SEGI+F  + GR V+
Sbjct: 735 IFQEPKSAHQVEQVLLAYSRCIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVV 794

Query: 620 MFGVPYVYTQSRILKARLEYL 640
           M G+P+   +S  L+ ++ YL
Sbjct: 795 MVGMPFPNIRSAELQEKMAYL 815



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 20/55 (36%), Positives = 35/55 (63%), Gaps = 1/55 (1%)

Query: 10 VYFPYDYI-YPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAY 63
          ++FP+ +  Y  Q  +M EL R L+A   G+ E P+GTGK++SL+   +++ R +
Sbjct: 11 IHFPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWLRDF 65


>gi|212549538 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12 [Homo
           sapiens]
          Length = 906

 Score =  124 bits (312), Expect = 2e-28
 Identities = 99/362 (27%), Positives = 164/362 (45%), Gaps = 46/362 (12%)

Query: 395 SPLTLLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSV 454
           SPL  +  F   ++T  +   +I+     R  +++   L F  ++ ++    V +  ++V
Sbjct: 561 SPLMHIEGFLAALTTANQDGRVILS----RQGSLSQSTLKFLLLNPAVHFAQVVKECRAV 616

Query: 455 IITSGTLSPLDIYPKILDFHPVTMATFTMTLARVC------------LCPMIIGRGNDQV 502
           +I  GT+ P+       +F    +A   +   RV             + P++I  G    
Sbjct: 617 VIAGGTMQPVS------NFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGVSNQ 670

Query: 503 AISSKFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQ 562
            +   F+ R+   ++   G +L  +  VV  G+V FF SY+Y+    A W + G+L  + 
Sbjct: 671 PLEFTFQKRDLPQMMDEVGRILCNLCGVVSGGVVCFFPSYEYLRQVHAHWEKGGLLGRLA 730

Query: 563 RNKLLFIETQDGAETSVALEKYQ---EACENGR----GAILLSVARGKVSEGIDFVHHYG 615
             K +F E +   +    L  Y    +AC   R    GA+LLSV  GK+SEGI+F  + G
Sbjct: 731 ARKKIFQEPKSAHQVEQVLLAYSRCLQACGQERGPVTGALLLSVVGGKMSEGINFSDNLG 790

Query: 616 RAVIMFGVPYVYTQSRILKARLEYL-----RDQFQIRENDFLTFD-AMRHAAQCVGRAIR 669
           R V+M G+P+   +S  L+ ++ YL     R   Q      L  +  M+   Q +GRAIR
Sbjct: 791 RCVVMVGMPFPNIRSAELQEKMAYLDQTLPRAPGQAHPGKALVENLCMKAVNQSIGRAIR 850

Query: 670 GKTDYGLMVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFH 729
            + D+  +V  D+R+AR     KLP WI+     A + +    G  +A        Q FH
Sbjct: 851 HQKDFASIVLLDQRYARPPVLAKLPAWIR-----ARVEVKATFGPAIA------AVQKFH 899

Query: 730 RE 731
           RE
Sbjct: 900 RE 901



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 54/210 (25%), Positives = 95/210 (45%), Gaps = 20/210 (9%)

Query: 67  VTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRF 126
           +TK+ +CSRT  ++ + + E++K         G+ +  +  +L SR+NLC++ +V  L  
Sbjct: 226 ITKIYHCSRTHSQLAQFVHEVKK------SPFGKDVRLV--SLGSRQNLCVNEDVRSLGS 277

Query: 127 GKDVDGKCHSLTASYVRAQYQHDTSLPH---------CRFYEEFDAHGREVPLPAGIYNL 177
            + ++ +C  +  S    +   +   P          C FY             A + ++
Sbjct: 278 VQLINNRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDM 337

Query: 178 DDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAH 237
           + L ALG+    CPY+ +R +I  A +VV  Y  LL           L +  VV+ DEAH
Sbjct: 338 EQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRL-QDQVVIIDEAH 396

Query: 238 NIDNVCIDSMSVNLTRRTLDRCQGNLETLQ 267
           N+ +      SV ++   L  CQ + + LQ
Sbjct: 397 NLIDTTTSMHSVEVSGSQL--CQAHSQLLQ 424



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 20/55 (36%), Positives = 35/55 (63%), Gaps = 1/55 (1%)

Query: 10 VYFPYDYI-YPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAY 63
          ++FP+ +  Y  Q  +M EL R L+A   G+ E P+GTGK++SL+   +++ R +
Sbjct: 11 IHFPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWLRDF 65


>gi|100913204 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
           isoform 2 [Homo sapiens]
          Length = 856

 Score =  113 bits (282), Expect = 7e-25
 Identities = 161/715 (22%), Positives = 284/715 (39%), Gaps = 139/715 (19%)

Query: 67  VTKLIYCSRTVPEIEKVIEELRKLLNFYEKQEGEKLPFLGLALSSRKNLCIHPEVTPLRF 126
           +TK+ YCSRT  ++ + + E++K         G+ +  +  +L SR+NLC++ +V  L  
Sbjct: 226 ITKIYYCSRTHSQLAQFVHEVKK------SPFGKDVRLV--SLGSRQNLCVNEDVKSLGS 277

Query: 127 GKDVDGKCHSLTASYVRAQYQHDTSLPH---------CRFYEEFDAHGREVPLPAGIYNL 177
            + ++ +C  +  S    +   +   P          C FY             A + ++
Sbjct: 278 VQLINDRCVDMQRSRHEKKKGAEEEKPKRRRQEKQAACPFYNHEQMGLLRDEALAEVKDM 337

Query: 178 DDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIADLVSKELARKAVVVFDEAH 237
           + L ALG+    CPY+ +R +I  A +VV  Y  LL           L +  VV+ DEAH
Sbjct: 338 EQLLALGKEARACPYYGSRLAIPAAQLVVLPYQMLLHAATRQAAGIRL-QDQVVIIDEAH 396

Query: 238 NIDNVCIDSMSVNLTRRTLDRCQGN---LETLQKTVLRIKETDEQRLR------DEYRRL 288
           N+ +      SV ++   L  CQ +   L+ +++   R+K  +   L+      +++  +
Sbjct: 397 NLIDTITGMHSVEVSGSQL--CQAHSQLLQYVERYGKRLKAKNLMYLKQILYLLEKFVAV 454

Query: 289 VEGLREASAARETDAHLANPV--LPDEVLQEAVPG-SIRTAEHFL--GFLRRLLEYVKWR 343
           + G  + +   ++ +     +  + D + Q  +   ++   + +     + R L     R
Sbjct: 455 LGGNIKQNPNTQSLSQTGTELKTINDFLFQSQIDNINLFKVQRYCEKSMISRKLFGFTER 514

Query: 344 LRVQHVVQESPPA-----FLSGLAQRVCIQRKPLRFCAERLRSLLHTLEITDLADFSPLT 398
                  +E P       FL  L  R            E L +     + + L   SPL 
Sbjct: 515 YGAVFSSREQPKLAGFQQFLQSLQPRT----------TEALAAPADESQASTLRPASPLM 564

Query: 399 LLANFATLVSTYAKGFTIIIEPFDDRTPTIANPILHFSCMDASLAIKPVFERFQSVIITS 458
            +  F   ++T  +   +I+     R  +++   L F  ++ ++    V +  ++V+I  
Sbjct: 565 HIQGFLAALTTANQDGRVILS----RQGSLSQSTLKFLLLNPAVHFAQVVKECRAVVIAG 620

Query: 459 GTLSPLDIYPKILDFHPVTMATFTMTLARVC------------LCPMIIGRGNDQVAISS 506
           GT+ P+       DF    +A   +   RV             + P++I  G     +  
Sbjct: 621 GTMQPVS------DFRQQLLACAGVEAERVVEFSCGHVIPPDNILPLVICSGISNQPLEF 674

Query: 507 KFETREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKL 566
            F+ RE                  +P  I        + E   A   EQ +L        
Sbjct: 675 TFQKRE------------------LPQMI--------FQEPKSAHQVEQVLL-------- 700

Query: 567 LFIETQDGAETSVALEKYQEACENGRG----AILLSVARGKVSEGIDFVHHYGRAVIMFG 622
                        A  +  +AC   RG    A+LLSV  GK+SEGI+F  + GR V+M G
Sbjct: 701 -------------AYSRCIQACGQERGQVTGALLLSVVGGKMSEGINFSDNLGRCVVMVG 747

Query: 623 VPYVYTQSRILKARLEYL-----RDQFQIRENDFLTFD-AMRHAAQCVGRAIRGKTDYGL 676
           +P+   +S  L+ ++ YL     R   Q      L  +  M+   Q +GRAIR + D+  
Sbjct: 748 MPFPNIRSAELQEKMAYLDQTLPRAPGQAPPGKALVENLCMKAVNQSIGRAIRHQKDFAS 807

Query: 677 MVFADKRFARGDKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHRE 731
           +V  D+R+AR     KLP WI+     A + +    G  +A        Q FHRE
Sbjct: 808 VVLLDQRYARPPVLAKLPAWIR-----ARVEVKATFGPAIA------AVQKFHRE 851



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 20/55 (36%), Positives = 35/55 (63%), Gaps = 1/55 (1%)

Query: 10 VYFPYDYI-YPEQFSYMRELKRTLDAKGHGVLEMPSGTGKTVSLLALIMAYQRAY 63
          ++FP+ +  Y  Q  +M EL R L+A   G+ E P+GTGK++SL+   +++ R +
Sbjct: 11 IHFPFPFTPYSIQEDFMAELYRVLEAGKIGIFESPTGTGKSLSLICGALSWLRDF 65


>gi|239755744 PREDICTED: similar to Putative ATP-dependent RNA
           helicase DDX11-like protein [Homo sapiens]
          Length = 223

 Score =  107 bits (268), Expect = 3e-23
 Identities = 75/224 (33%), Positives = 110/224 (49%), Gaps = 24/224 (10%)

Query: 521 GNLLLEMSAVVPDGIVAFFTSYQYMESTVASWYEQGILENIQRNKLLFIETQDGAETSVA 580
           G +L  +  VV  G+V FF SY+Y+    A W + G+L  +   K +F E +   +    
Sbjct: 6   GRILCNLCVVVSGGVVCFFPSYEYLRQVHAHWEKGGLLGRLAARKKIFQEPKSAHQVEQV 65

Query: 581 LEKYQ---EACENGRG----AILLSVARGKVSEGIDFVHHYGRAVIMFGVPYVYTQSRIL 633
           L  Y    +AC   RG    A+LLSV  GK+SEGI+F  + GR V+M G+P+   +S  L
Sbjct: 66  LLAYSRCIQACGQERGQVTEALLLSVVGGKMSEGINFSDNLGRCVVMVGMPFPNIRSAEL 125

Query: 634 KARLEYL-----RDQFQIRENDFLTFD-AMRHAAQCVGRAIRGKTDYGLMVFADKRFARG 687
           + ++ YL     R   Q      L  +  M+   Q +GRAIR + D+  +V  D+R+AR 
Sbjct: 126 QEKMAYLDQTLPRAPGQAPPGKALVENLCMKAVNQSIGRAIRHQKDFASIVLLDQRYARP 185

Query: 688 DKRGKLPRWIQEHLTDANLNLTVDEGVQVAKYFLRQMAQPFHRE 731
               KLP WI+     A + +    G  +A        Q FHRE
Sbjct: 186 PVLAKLPAWIR-----ARVEVKATFGPAIA------AVQKFHRE 218


>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
          Length = 1397

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 1/41 (2%)

Query: 162 DAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHA 202
           D  G + P P+G+  LDDL  +G R  + P F  R  +LHA
Sbjct: 302 DLPGPQAPPPSGLQGLDDLGYIGYR-SYSPSFQRRTGLLHA 341


>gi|63055049 phosphoglucomutase 2 [Homo sapiens]
          Length = 612

 Score = 32.3 bits (72), Expect = 1.7
 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 1/74 (1%)

Query: 160 EFDAHGREVPLPAGIYNLDDLKALGRRQGWCPYFLARYSILHANVVVYSYHYLLDPKIAD 219
           EF   G    +  GI  ++DL  +   QG+C Y   ++S L    +V S+     P    
Sbjct: 56  EFGTAGLRAAMGPGISRMNDLTIIQTTQGFCRYLEKQFSDLKQKGIVISFDARAHPSSGG 115

Query: 220 LVSKELARKAVVVF 233
             S+  AR A   F
Sbjct: 116 -SSRRFARLAATTF 128


>gi|51702248 G protein-coupled receptor associated sorting protein 2
           [Homo sapiens]
          Length = 838

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 37/167 (22%), Positives = 73/167 (43%), Gaps = 37/167 (22%)

Query: 330 LGFLRRLLEYVKWRLR---VQHVVQESPP-AFLSGLAQRVCIQRKPLRFCAERLRSLLHT 385
           +  +  LL Y   R+R   +++++  +PP   L+ +   +C      + C E L   + +
Sbjct: 640 VSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETFIC------QVCEETLAHSVDS 693

Query: 386 LE-ITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRT--------------PTIAN 430
           LE +T +     LT+  ++ TL++ Y  GF  ++   + RT              P +A 
Sbjct: 694 LEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAK 753

Query: 431 PILH----------FSCMDASLAIKPVFERFQSV--IITSGTLSPLD 465
            +            F+  + +  I+ V + FQ++  II SG +S +D
Sbjct: 754 KLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSLID 800


>gi|19923967 G protein-coupled receptor associated sorting protein 2
           [Homo sapiens]
          Length = 838

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 37/167 (22%), Positives = 73/167 (43%), Gaps = 37/167 (22%)

Query: 330 LGFLRRLLEYVKWRLR---VQHVVQESPP-AFLSGLAQRVCIQRKPLRFCAERLRSLLHT 385
           +  +  LL Y   R+R   +++++  +PP   L+ +   +C      + C E L   + +
Sbjct: 640 VSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETFIC------QVCEETLAHSVDS 693

Query: 386 LE-ITDLADFSPLTLLANFATLVSTYAKGFTIIIEPFDDRT--------------PTIAN 430
           LE +T +     LT+  ++ TL++ Y  GF  ++   + RT              P +A 
Sbjct: 694 LEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAK 753

Query: 431 PILH----------FSCMDASLAIKPVFERFQSV--IITSGTLSPLD 465
            +            F+  + +  I+ V + FQ++  II SG +S +D
Sbjct: 754 KLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSLID 800


>gi|4759336 Fanconi anemia, complementation group G [Homo sapiens]
          Length = 622

 Score = 31.2 bits (69), Expect = 3.7
 Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 342 WRLRVQHVVQESPPAFLSGLAQRVCIQRKPLRFCAERLRSLLHTLE-ITDLADFSPL--T 398
           WR +   +V+++  A  SGL  R   +++  +   E LR LLH+L+ +       PL  T
Sbjct: 16  WREKNDRLVRQAKVAQNSGLTLR---RQQLAQDALEGLRGLLHSLQGLPAAVPVLPLELT 72

Query: 399 LLANFATLVSTYAKGFT 415
           +  NF  L ++ A+GFT
Sbjct: 73  VTCNFIILRASLAQGFT 89


>gi|110349767 calcium channel, voltage-dependent, L type, alpha 1S
            subunit [Homo sapiens]
          Length = 1873

 Score = 30.8 bits (68), Expect = 4.9
 Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 2/82 (2%)

Query: 263  LETLQKTVLRIK-ETDEQRLRDEYRRLVEGLREASAARETDAHLANPVLPDEVLQEAVPG 321
            L  L +T L+IK E + ++  +E R +++ + + ++ +  D  +  P+  DEV       
Sbjct: 1467 LFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLD-QVIPPIGDDEVTVGKFYA 1525

Query: 322  SIRTAEHFLGFLRRLLEYVKWR 343
            +    EHF  F++R  EY  +R
Sbjct: 1526 TFLIQEHFRKFMKRQEEYYGYR 1547


>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
          Length = 1476

 Score = 30.8 bits (68), Expect = 4.9
 Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 4/104 (3%)

Query: 251 LTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLREASAARETDAHLANPVL 310
           L R  L      L++L+  V ++ E + + L  E +R +E      +  E     A P L
Sbjct: 393 LLRTRLGEAHAELDSLRHQVDQLAEENVE-LELELQRSLEP--PPGSPGEAPLAGAAPSL 449

Query: 311 PDEVLQEAVPGSIRTAEHFLGFLRRLLEYVKWRLRVQHVVQESP 354
            DEV +EA  G +RT E     LR LL+ ++ +   QH + E+P
Sbjct: 450 QDEV-REAEAGRLRTLERENRELRGLLQVLQGQPGGQHPLLEAP 492


>gi|91598777 transmembrane protein 146 [Homo sapiens]
          Length = 798

 Score = 30.4 bits (67), Expect = 6.4
 Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 10/70 (14%)

Query: 500 DQVAISSKFE----------TREDIAVIRNYGNLLLEMSAVVPDGIVAFFTSYQYMESTV 549
           DQ   SS FE          T  ++AVI    NL      +VP  I+ F   Y + E   
Sbjct: 282 DQTLFSSIFEAKITIHNIAVTENELAVITREDNLYYGNLGIVPSSIIKFADQYIWSEDVA 341

Query: 550 ASWYEQGILE 559
             +   G LE
Sbjct: 342 LMFRSPGTLE 351


>gi|162287219 prune homolog 2 [Homo sapiens]
          Length = 3088

 Score = 30.0 bits (66), Expect = 8.3
 Identities = 24/94 (25%), Positives = 37/94 (39%), Gaps = 7/94 (7%)

Query: 235  EAHNIDNVCIDSMSVNLTRRTLDRCQGNLETLQKTVLRIKETDEQRLRDEYRRLVEGLRE 294
            +A +  ++C DS +   T + L  C G      +  L   E DE+ + +  R  V    E
Sbjct: 2100 QASDSPDICHDSEAKQETEKHLSACMGPEVESSELCLTEPEIDEEPIYEPGREFVPSNAE 2159

Query: 295  ASAARETDAHLANPVLPDEVLQEAVPGSIRTAEH 328
              +   T       VLP    Q  + GS + A H
Sbjct: 2160 LDSENAT-------VLPPIGYQADIKGSSQPASH 2186


>gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens]
          Length = 6306

 Score = 30.0 bits (66), Expect = 8.3
 Identities = 15/45 (33%), Positives = 25/45 (55%)

Query: 567  LFIETQDGAETSVALEKYQEACENGRGAILLSVARGKVSEGIDFV 611
            LF+E Q+  +T V L  ++     G+ A+   V  G  +EG+DF+
Sbjct: 2594 LFVEVQEQPQTLVELMIHRTGGSLGQVAVEWRVVGGTATEGLDFI 2638


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,245,836
Number of Sequences: 37866
Number of extensions: 1110337
Number of successful extensions: 2825
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2754
Number of HSP's gapped (non-prelim): 39
length of query: 760
length of database: 18,247,518
effective HSP length: 110
effective length of query: 650
effective length of database: 14,082,258
effective search space: 9153467700
effective search space used: 9153467700
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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