Guide to the Human Genome
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Search of human proteins with 157502222

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157502222 granulysin isoform 519 [Homo sapiens]
         (130 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157502222 granulysin isoform 519 [Homo sapiens]                    268   7e-73
gi|7108344 granulysin isoform NKG5 [Homo sapiens]                     265   1e-71
gi|145977198 prosaposin-like protein 1 [Homo sapiens]                  34   0.037
gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]         30   0.54 
gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]         30   0.54 
gi|11386147 prosaposin isoform a preproprotein [Homo sapiens]          30   0.54 
gi|239754072 PREDICTED: hypothetical protein [Homo sapiens]            29   1.2  
gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]       28   1.6  
gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]       28   1.6  
gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]       28   1.6  
gi|88758613 CD93 antigen precursor [Homo sapiens]                      28   2.1  
gi|148596944 C2 calcium-dependent domain containing 3 [Homo sapi...    27   3.5  
gi|5729858 nuclear receptor coactivator 2 [Homo sapiens]               27   4.6  
gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]               26   7.8  
gi|239748599 PREDICTED: hypothetical protein XP_002346728 [Homo ...    26   7.8  
gi|239742616 PREDICTED: hypothetical protein XP_002342550 [Homo ...    26   7.8  
gi|217272887 WD repeat domain 63 [Homo sapiens]                        26   7.8  

>gi|157502222 granulysin isoform 519 [Homo sapiens]
          Length = 130

 Score =  268 bits (686), Expect = 7e-73
 Identities = 130/130 (100%), Positives = 130/130 (100%)

Query: 1   MEGLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQK 60
           MEGLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQK
Sbjct: 1   MEGLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQK 60

Query: 61  LKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDL 120
           LKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDL
Sbjct: 61  LKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDL 120

Query: 121 RLCIPSTGPL 130
           RLCIPSTGPL
Sbjct: 121 RLCIPSTGPL 130


>gi|7108344 granulysin isoform NKG5 [Homo sapiens]
          Length = 145

 Score =  265 bits (676), Expect = 1e-71
 Identities = 128/128 (100%), Positives = 128/128 (100%)

Query: 3   GLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLK 62
           GLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLK
Sbjct: 18  GLVFSRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLK 77

Query: 63  KMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRL 122
           KMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRL
Sbjct: 78  KMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGETAQQICEDLRL 137

Query: 123 CIPSTGPL 130
           CIPSTGPL
Sbjct: 138 CIPSTGPL 145


>gi|145977198 prosaposin-like protein 1 [Homo sapiens]
          Length = 521

 Score = 33.9 bits (76), Expect = 0.037
 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 2/71 (2%)

Query: 54  CLTIVQKLKK-MVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 112
           C+ +VQKL   ++   ++  +++A  RVC    +     C   +  Y   + Q LVA  T
Sbjct: 297 CMNVVQKLDHWLMSNSSELMITHALERVCSVMPASITKECIILVDTYSPSLVQ-LVAKIT 355

Query: 113 AQQICEDLRLC 123
            +++C+ +RLC
Sbjct: 356 PEKVCKFIRLC 366


>gi|110224479 prosaposin isoform c preproprotein [Homo sapiens]
          Length = 526

 Score = 30.0 bits (66), Expect = 0.54
 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 54  CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 112
           C  +V+++ K++D   T++ + +A  ++C        + C+  +  Y S +   L+   +
Sbjct: 320 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 379

Query: 113 AQQICEDLRLC 123
            + +C  L LC
Sbjct: 380 PELVCSMLHLC 390


>gi|110224476 prosaposin isoform b preproprotein [Homo sapiens]
          Length = 527

 Score = 30.0 bits (66), Expect = 0.54
 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 54  CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 112
           C  +V+++ K++D   T++ + +A  ++C        + C+  +  Y S +   L+   +
Sbjct: 321 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 380

Query: 113 AQQICEDLRLC 123
            + +C  L LC
Sbjct: 381 PELVCSMLHLC 391


>gi|11386147 prosaposin isoform a preproprotein [Homo sapiens]
          Length = 524

 Score = 30.0 bits (66), Expect = 0.54
 Identities = 15/71 (21%), Positives = 35/71 (49%), Gaps = 1/71 (1%)

Query: 54  CLTIVQKLKKMVDK-PTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 112
           C  +V+++ K++D   T++ + +A  ++C        + C+  +  Y S +   L+   +
Sbjct: 318 CEFLVKEVTKLIDNNKTEKEILDAFDKMCSKLPKSLSEECQEVVDTYGSSILSILLEEVS 377

Query: 113 AQQICEDLRLC 123
            + +C  L LC
Sbjct: 378 PELVCSMLHLC 388


>gi|239754072 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 379

 Score = 28.9 bits (63), Expect = 1.2
 Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 4/64 (6%)

Query: 18  RAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLKKMVDKPTQRSVSNAA 77
           RA LR    SC C  +EG + +LL +T+E  R+  + L I+ K+K    +  ++SV    
Sbjct: 305 RAVLRALVLSC-CFPEEGLR-ELLEQTRE--REEGSTLKILSKVKFEACRKEEKSVEKCR 360

Query: 78  TRVC 81
            RVC
Sbjct: 361 YRVC 364


>gi|190343010 SP110 nuclear body protein isoform a [Homo sapiens]
          Length = 689

 Score = 28.5 bits (62), Expect = 1.6
 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 17/80 (21%)

Query: 58  VQKLKKMVDKPTQRS------------VSNAATRVCRTGRSRWR----DVCRNFMRRYQS 101
           +Q+  ++VDK TQR             V  A T+  R  RS+ +    D+C +  RR+Q 
Sbjct: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQK 444

Query: 102 RV-TQGLVAGETAQQICEDL 120
            +  +G    +T    C  L
Sbjct: 445 NIHRRGKPKSDTVDFHCSKL 464


>gi|190343008 SP110 nuclear body protein isoform b [Homo sapiens]
          Length = 549

 Score = 28.5 bits (62), Expect = 1.6
 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 17/80 (21%)

Query: 58  VQKLKKMVDKPTQRS------------VSNAATRVCRTGRSRWR----DVCRNFMRRYQS 101
           +Q+  ++VDK TQR             V  A T+  R  RS+ +    D+C +  RR+Q 
Sbjct: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQK 444

Query: 102 RV-TQGLVAGETAQQICEDL 120
            +  +G    +T    C  L
Sbjct: 445 NIHRRGKPKSDTVDFHCSKL 464


>gi|190343006 SP110 nuclear body protein isoform c [Homo sapiens]
          Length = 713

 Score = 28.5 bits (62), Expect = 1.6
 Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 17/80 (21%)

Query: 58  VQKLKKMVDKPTQRS------------VSNAATRVCRTGRSRWR----DVCRNFMRRYQS 101
           +Q+  ++VDK TQR             V  A T+  R  RS+ +    D+C +  RR+Q 
Sbjct: 385 IQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRSKEKKKEKDICSSSKRRFQK 444

Query: 102 RV-TQGLVAGETAQQICEDL 120
            +  +G    +T    C  L
Sbjct: 445 NIHRRGKPKSDTVDFHCSKL 464


>gi|88758613 CD93 antigen precursor [Homo sapiens]
          Length = 652

 Score = 28.1 bits (61), Expect = 2.1
 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 81  CRTGRSRWRDVCRNFMRRYQSRVTQGLV-AGETAQQICEDLRLCIPSTGPL 130
           C  GRS     C N    +     +G V AGE   Q C+D+  C+   GPL
Sbjct: 389 CALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQ-CQDVDECVGPGGPL 438


>gi|148596944 C2 calcium-dependent domain containing 3 [Homo
           sapiens]
          Length = 1963

 Score = 27.3 bits (59), Expect = 3.5
 Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 12/92 (13%)

Query: 7   SRLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTI--------V 58
           S   P+   +A++H      SC   +   P  DLL+   E G   R  + I         
Sbjct: 287 SEFQPQIRTVAKSH----SDSCILSSNNLPTKDLLSALLEQGNKLRNAMVISAMKSSPET 342

Query: 59  QKLKKMVDKPTQRSVSNAATRVCRTGRSRWRD 90
             L   V  P       A+T++    R+R++D
Sbjct: 343 SMLLDQVHPPINEDSLRASTQIRAFSRNRFKD 374


>gi|5729858 nuclear receptor coactivator 2 [Homo sapiens]
          Length = 1464

 Score = 26.9 bits (58), Expect = 4.6
 Identities = 22/105 (20%), Positives = 41/105 (39%), Gaps = 21/105 (20%)

Query: 12  EYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLKKMVDKPTQR 71
           E +D   AH + E   C  ++Q           +E G D ++CL  V +   M ++P   
Sbjct: 213 EGHDNQEAHQKYETMQCFAVSQP-------KSIKEEGEDLQSCLICVARRVPMKERPVLP 265

Query: 72  SVSNAATRVCRTG--------------RSRWRDVCRNFMRRYQSR 102
           S  +  TR    G              +  W D+ R  ++++ ++
Sbjct: 266 SSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCIQKFHAQ 310


>gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]
          Length = 466

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 16/54 (29%), Positives = 23/54 (42%)

Query: 59  QKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGLVAGET 112
           QK  K+V K +  + +N   R     R    D C+N  +  Q R      AG+T
Sbjct: 12  QKYPKIVKKSSDTAENNLPQRSRGKTRRMMNDSCQNLPKINQQRPRSKTTAGKT 65


>gi|239748599 PREDICTED: hypothetical protein XP_002346728 [Homo
           sapiens]
          Length = 285

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 3/52 (5%)

Query: 30  CLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVC 81
           C  +EG + +LL +T+E  R+  + L I+ K+K    +  ++SV     RVC
Sbjct: 222 CFPEEGLR-ELLEQTRE--REEGSTLKILSKVKFEACRKEEKSVEKCRYRVC 270


>gi|239742616 PREDICTED: hypothetical protein XP_002342550 [Homo
           sapiens]
          Length = 285

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 3/52 (5%)

Query: 30  CLAQEGPQGDLLTKTQELGRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVC 81
           C  +EG + +LL +T+E  R+  + L I+ K+K    +  ++SV     RVC
Sbjct: 222 CFPEEGLR-ELLEQTRE--REEGSTLKILSKVKFEACRKEEKSVEKCRYRVC 270


>gi|217272887 WD repeat domain 63 [Homo sapiens]
          Length = 891

 Score = 26.2 bits (56), Expect = 7.8
 Identities = 11/38 (28%), Positives = 20/38 (52%)

Query: 39  DLLTKTQELGRDYRTCLTIVQKLKKMVDKPTQRSVSNA 76
           DLL KT E  +    C+T++  +K  +    Q+ ++ A
Sbjct: 744 DLLEKTHEPAQSQNICITMITYIKPWIFSSKQQFIATA 781


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,170,060
Number of Sequences: 37866
Number of extensions: 194621
Number of successful extensions: 446
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 442
Number of HSP's gapped (non-prelim): 17
length of query: 130
length of database: 18,247,518
effective HSP length: 90
effective length of query: 40
effective length of database: 14,839,578
effective search space: 593583120
effective search space used: 593583120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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