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Search of human proteins with 157426891
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens]
(775 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens] 1585 0.0
gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo sapi... 533 e-151
gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo sapi... 532 e-151
gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo sapi... 532 e-151
gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens] 532 e-151
gi|153945836 endothelin converting enzyme 2 isoform E [Homo sapi... 531 e-151
gi|153945771 endothelin converting enzyme 2 isoform D [Homo sapi... 529 e-150
gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens] 529 e-150
gi|153945761 endothelin converting enzyme 2 isoform A [Homo sapi... 529 e-150
gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens] 477 e-134
gi|116256333 membrane metallo-endopeptidase [Homo sapiens] 443 e-124
gi|116256331 membrane metallo-endopeptidase [Homo sapiens] 443 e-124
gi|116256327 membrane metallo-endopeptidase [Homo sapiens] 443 e-124
gi|116256329 membrane metallo-endopeptidase [Homo sapiens] 443 e-124
gi|90403592 phosphate-regulating neutral endopeptidase [Homo sap... 374 e-103
gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens] 278 2e-74
gi|239753431 PREDICTED: similar to endothelin converting enzyme-... 114 3e-25
gi|239747995 PREDICTED: hypothetical protein XP_002346505 [Homo ... 114 3e-25
gi|239741893 PREDICTED: hypothetical protein XP_002342317 [Homo ... 114 3e-25
gi|239740948 PREDICTED: hypothetical protein LOC644246 [Homo sap... 36 0.12
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 33 1.0
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 33 1.0
gi|56699473 zinc finger protein 192 [Homo sapiens] 32 1.7
gi|239744421 PREDICTED: hypothetical protein [Homo sapiens] 31 3.8
gi|6631102 protocadherin 8 isoform 1 precursor [Homo sapiens] 31 3.8
gi|30039692 NIMA-related kinase 8 [Homo sapiens] 31 5.0
gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens] 31 5.0
gi|33188461 GATA binding protein 4 [Homo sapiens] 30 6.5
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 30 6.5
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 30 6.5
>gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens]
Length = 775
Score = 1585 bits (4105), Expect = 0.0
Identities = 775/775 (100%), Positives = 775/775 (100%)
Query: 1 MEPPYSLTAHYDEFQEVKYVSRCGAGGARGASLPPGFPLGAARSATGARSGLPRWNRREV 60
MEPPYSLTAHYDEFQEVKYVSRCGAGGARGASLPPGFPLGAARSATGARSGLPRWNRREV
Sbjct: 1 MEPPYSLTAHYDEFQEVKYVSRCGAGGARGASLPPGFPLGAARSATGARSGLPRWNRREV 60
Query: 61 CLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLAANLDASI 120
CLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLAANLDASI
Sbjct: 61 CLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLAANLDASI 120
Query: 121 DPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPGGGPGGAAQRKV 180
DPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPGGGPGGAAQRKV
Sbjct: 121 DPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPGGGPGGAAQRKV 180
Query: 181 RAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGVAARWDLNRLLYKAQGVYS 240
RAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGVAARWDLNRLLYKAQGVYS
Sbjct: 181 RAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGVAARWDLNRLLYKAQGVYS 240
Query: 241 AAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSL 300
AAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSL
Sbjct: 241 AAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSL 300
Query: 301 LGADAVEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLL 360
LGADAVEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLL
Sbjct: 301 LGADAVEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLL 360
Query: 361 DQIFQEDFSEEEEVVLLATDYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREA 420
DQIFQEDFSEEEEVVLLATDYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREA
Sbjct: 361 DQIFQEDFSEEEEVVLLATDYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREA 420
Query: 421 LHELAQEMEGSDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYI 480
LHELAQEMEGSDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYI
Sbjct: 421 LHELAQEMEGSDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYI 480
Query: 481 LGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDFLLKPDAVDKEYEFEVHEKTYFKNIL 540
LGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDFLLKPDAVDKEYEFEVHEKTYFKNIL
Sbjct: 481 LGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDFLLKPDAVDKEYEFEVHEKTYFKNIL 540
Query: 541 NSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQS 600
NSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQS
Sbjct: 541 NSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQS 600
Query: 601 LNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVY 660
LNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVY
Sbjct: 601 LNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVY 660
Query: 661 NQRVNGKHTLGENIADMGGLKLAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWC 720
NQRVNGKHTLGENIADMGGLKLAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWC
Sbjct: 661 NQRVNGKHTLGENIADMGGLKLAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWC 720
Query: 721 IKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
IKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW
Sbjct: 721 IKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
>gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo
sapiens]
Length = 758
Score = 533 bits (1373), Expect = e-151
Identities = 281/749 (37%), Positives = 434/749 (57%), Gaps = 25/749 (3%)
Query: 33 LPPGFPLGAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPVAAGG 92
LPP + +G R R + ++ ++ AAGL A LAA L ++Y
Sbjct: 29 LPPSLQVNFHSPRSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAA-LGIQYQT------ 81
Query: 93 GACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAA 152
P C + + L++ +D ++DPC DF+S+ACGGW++ + +PD +GT +
Sbjct: 82 -RSPSVCLSEACVSVTSSILSS-MDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSN 139
Query: 153 IGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWD 212
+ E N+ ++ LL A+RK + ++R+C++ IE L +P++E+IE GGW+
Sbjct: 140 LWEHNQAIIKHLLENSTASVS-EAERKAQVYYRACMNETRIEELRAKPLMELIERLGGWN 198
Query: 213 LGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPE 272
+ G A+ + L Y + FS+ VS D +NS+ VI++DQ GL LP
Sbjct: 199 ITGPW------AKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPS 252
Query: 273 RTLYLAQDEDSEKILAAYRVFMERVLSLLGA---DAVEQKAQEILQVEQQLANITVSEHD 329
R YL + E+ EK+L Y +M ++ LLG +A+ + Q+IL E LANIT+ +
Sbjct: 253 RDYYLNKTEN-EKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQ-- 309
Query: 330 DLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLATDYMQQVSQL 388
+ RRD +Y+KVT +LQ + P + W L+ IF + +E E +V+ +Y++Q+S L
Sbjct: 310 EKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYLEQISTL 369
Query: 389 IRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELARVCLGQANR 447
I +T +L+NY++W +V S L F++A + + M G+ K + C+
Sbjct: 370 INTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTEN 429
Query: 448 HFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMM 507
+ G ALG +FV F+ SK+ +++ +IK + L L WMD ETR +A+ K +
Sbjct: 430 NLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIY 489
Query: 508 VMVGYPDFLLKPDAVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLP 566
M+GYP+F++ P +DK + ++ YF+N + FS +++ ++R+ ++ W +
Sbjct: 490 NMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMT 549
Query: 567 PQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYD 626
P +NAYY P KN++VFPAGILQ Y P++LN+GGIG ++GHELTH +DD G +YD
Sbjct: 550 PPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYD 609
Query: 627 RSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYHA 686
+ GNL WW +S F R+ EC+V Y N++V + VNG+HTLGENIAD GGLK AY A
Sbjct: 610 KDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRA 669
Query: 687 YQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLG 746
YQ WV+++G EH LP L T++QLFF+ FAQ WC R +S + ++TD H+P +RV+G
Sbjct: 670 YQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIG 729
Query: 747 SVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
S+S +EF F CP SPMNP HKC VW
Sbjct: 730 SLSNSKEFSEHFRCPPGSPMNPPHKCEVW 758
>gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo
sapiens]
Length = 767
Score = 532 bits (1371), Expect = e-151
Identities = 281/754 (37%), Positives = 436/754 (57%), Gaps = 25/754 (3%)
Query: 28 ARGASLPPGFPLGAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGP 87
+ G + P G + +G R R + ++ ++ AAGL A LAA L ++Y
Sbjct: 33 SEGDAYPNGLQVNFHSPRSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAA-LGIQYQT- 90
Query: 88 VAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTY 147
P C + + L++ +D ++DPC DF+S+ACGGW++ + +PD +
Sbjct: 91 ------RSPSVCLSEACVSVTSSILSS-MDPTVDPCHDFFSYACGGWIKANPVPDGHSRW 143
Query: 148 GTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIED 207
GT + + E N+ ++ LL A+RK + ++R+C++ IE L +P++E+IE
Sbjct: 144 GTFSNLWEHNQAIIKHLLENSTASVS-EAERKAQVYYRACMNETRIEELRAKPLMELIER 202
Query: 208 CGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDG 267
GGW++ G A+ + L Y + FS+ VS D +NS+ VI++DQ G
Sbjct: 203 LGGWNITGPW------AKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSG 256
Query: 268 LTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGA---DAVEQKAQEILQVEQQLANIT 324
L LP R YL + E+ EK+L Y +M ++ LLG +A+ + Q+IL E LANIT
Sbjct: 257 LGLPSRDYYLNKTEN-EKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANIT 315
Query: 325 VSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLATDYMQ 383
+ + + RRD +Y+KVT +LQ + P + W L+ IF + +E E +V+ +Y++
Sbjct: 316 IPQ--EKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYLE 373
Query: 384 QVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELARVCL 442
Q+S LI +T +L+NY++W +V S L F++A + + M G+ K + C+
Sbjct: 374 QISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCV 433
Query: 443 GQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAK 502
+ G ALG +FV F+ SK+ +++ +IK + L L WMD ETR +A+ K
Sbjct: 434 SDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEK 493
Query: 503 LQYMMVMVGYPDFLLKPDAVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKS 561
+ M+GYP+F++ P +DK + ++ YF+N + FS +++ ++R+ ++
Sbjct: 494 ADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRD 553
Query: 562 TWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDW 621
W + P +NAYY P KN++VFPAGILQ Y P++LN+GGIG ++GHELTH +DD
Sbjct: 554 QWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQ 613
Query: 622 GGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLK 681
G +YD+ GNL WW +S F R+ EC+V Y N++V + VNG+HTLGENIAD GGLK
Sbjct: 614 GREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLK 673
Query: 682 LAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEH 741
AY AYQ WV+++G EH LP L T++QLFF+ FAQ WC R +S + ++TD H+P
Sbjct: 674 AAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSR 733
Query: 742 YRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
+RV+GS+S +EF F CP SPMNP HKC VW
Sbjct: 734 FRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 767
>gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo
sapiens]
Length = 754
Score = 532 bits (1371), Expect = e-151
Identities = 281/754 (37%), Positives = 436/754 (57%), Gaps = 25/754 (3%)
Query: 28 ARGASLPPGFPLGAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGP 87
+ G + P G + +G R R + ++ ++ AAGL A LAA L ++Y
Sbjct: 20 SEGDAYPNGLQVNFHSPRSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAA-LGIQYQT- 77
Query: 88 VAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTY 147
P C + + L++ +D ++DPC DF+S+ACGGW++ + +PD +
Sbjct: 78 ------RSPSVCLSEACVSVTSSILSS-MDPTVDPCHDFFSYACGGWIKANPVPDGHSRW 130
Query: 148 GTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIED 207
GT + + E N+ ++ LL A+RK + ++R+C++ IE L +P++E+IE
Sbjct: 131 GTFSNLWEHNQAIIKHLLENSTASVS-EAERKAQVYYRACMNETRIEELRAKPLMELIER 189
Query: 208 CGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDG 267
GGW++ G A+ + L Y + FS+ VS D +NS+ VI++DQ G
Sbjct: 190 LGGWNITGPW------AKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSG 243
Query: 268 LTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGA---DAVEQKAQEILQVEQQLANIT 324
L LP R YL + E+ EK+L Y +M ++ LLG +A+ + Q+IL E LANIT
Sbjct: 244 LGLPSRDYYLNKTEN-EKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANIT 302
Query: 325 VSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLATDYMQ 383
+ + + RRD +Y+KVT +LQ + P + W L+ IF + +E E +V+ +Y++
Sbjct: 303 IPQ--EKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYLE 360
Query: 384 QVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELARVCL 442
Q+S LI +T +L+NY++W +V S L F++A + + M G+ K + C+
Sbjct: 361 QISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCV 420
Query: 443 GQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAK 502
+ G ALG +FV F+ SK+ +++ +IK + L L WMD ETR +A+ K
Sbjct: 421 SDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEK 480
Query: 503 LQYMMVMVGYPDFLLKPDAVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKS 561
+ M+GYP+F++ P +DK + ++ YF+N + FS +++ ++R+ ++
Sbjct: 481 ADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRD 540
Query: 562 TWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDW 621
W + P +NAYY P KN++VFPAGILQ Y P++LN+GGIG ++GHELTH +DD
Sbjct: 541 QWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQ 600
Query: 622 GGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLK 681
G +YD+ GNL WW +S F R+ EC+V Y N++V + VNG+HTLGENIAD GGLK
Sbjct: 601 GREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLK 660
Query: 682 LAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEH 741
AY AYQ WV+++G EH LP L T++QLFF+ FAQ WC R +S + ++TD H+P
Sbjct: 661 AAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSR 720
Query: 742 YRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
+RV+GS+S +EF F CP SPMNP HKC VW
Sbjct: 721 FRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 754
>gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens]
Length = 770
Score = 532 bits (1371), Expect = e-151
Identities = 281/754 (37%), Positives = 436/754 (57%), Gaps = 25/754 (3%)
Query: 28 ARGASLPPGFPLGAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYLGP 87
+ G + P G + +G R R + ++ ++ AAGL A LAA L ++Y
Sbjct: 36 SEGDAYPNGLQVNFHSPRSGQRCWAARTQVEKRLVVLVVLLAAGLVACLAA-LGIQYQT- 93
Query: 88 VAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTY 147
P C + + L++ +D ++DPC DF+S+ACGGW++ + +PD +
Sbjct: 94 ------RSPSVCLSEACVSVTSSILSS-MDPTVDPCHDFFSYACGGWIKANPVPDGHSRW 146
Query: 148 GTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIED 207
GT + + E N+ ++ LL A+RK + ++R+C++ IE L +P++E+IE
Sbjct: 147 GTFSNLWEHNQAIIKHLLENSTASVS-EAERKAQVYYRACMNETRIEELRAKPLMELIER 205
Query: 208 CGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDG 267
GGW++ G A+ + L Y + FS+ VS D +NS+ VI++DQ G
Sbjct: 206 LGGWNITGPW------AKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSG 259
Query: 268 LTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGA---DAVEQKAQEILQVEQQLANIT 324
L LP R YL + E+ EK+L Y +M ++ LLG +A+ + Q+IL E LANIT
Sbjct: 260 LGLPSRDYYLNKTEN-EKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANIT 318
Query: 325 VSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLATDYMQ 383
+ + + RRD +Y+KVT +LQ + P + W L+ IF + +E E +V+ +Y++
Sbjct: 319 IPQ--EKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYLE 376
Query: 384 QVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELARVCL 442
Q+S LI +T +L+NY++W +V S L F++A + + M G+ K + C+
Sbjct: 377 QISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCV 436
Query: 443 GQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAK 502
+ G ALG +FV F+ SK+ +++ +IK + L L WMD ETR +A+ K
Sbjct: 437 SDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEK 496
Query: 503 LQYMMVMVGYPDFLLKPDAVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKS 561
+ M+GYP+F++ P +DK + ++ YF+N + FS +++ ++R+ ++
Sbjct: 497 ADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRD 556
Query: 562 TWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDW 621
W + P +NAYY P KN++VFPAGILQ Y P++LN+GGIG ++GHELTH +DD
Sbjct: 557 QWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQ 616
Query: 622 GGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLK 681
G +YD+ GNL WW +S F R+ EC+V Y N++V + VNG+HTLGENIAD GGLK
Sbjct: 617 GREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLK 676
Query: 682 LAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEH 741
AY AYQ WV+++G EH LP L T++QLFF+ FAQ WC R +S + ++TD H+P
Sbjct: 677 AAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSR 736
Query: 742 YRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
+RV+GS+S +EF F CP SPMNP HKC VW
Sbjct: 737 FRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 770
>gi|153945836 endothelin converting enzyme 2 isoform E [Homo
sapiens]
Length = 765
Score = 531 bits (1369), Expect = e-151
Identities = 286/758 (37%), Positives = 435/758 (57%), Gaps = 34/758 (4%)
Query: 26 GGARGASLPPGFPLGAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYL 85
GGA ++ GF G R G+R+ L V + L+ AA L L A+ +
Sbjct: 34 GGASPDAMEVGFQKGT-RQLLGSRTQLEL-----VLAGASLLLAALLLGCLVALGVQYHR 87
Query: 86 GPVAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKL 145
P + E C R A + +LD + PC+DFY F+CGGW+RR+ +PD +
Sbjct: 88 DP--SHSTCLTEAC------IRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRS 139
Query: 146 TYGTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVI 205
+ T ++ +QN+ L+ LL A++K + F+ SCL + IE LG +P+ ++I
Sbjct: 140 RWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLI 199
Query: 206 EDCGGWDLGGAEERPGVAARWDLNR---LLYKAQGVYSAAALFSLTVSLDDRNSSRYVIR 262
E GGW++ G WD + +L G Y A F++ +S D ++S+ VI+
Sbjct: 200 EKIGGWNITGP---------WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQ 250
Query: 263 IDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGA--DAVEQKAQEILQVEQQL 320
+DQ GL LP R YL + + EK+L AY +ME + LLG + ++ Q++L++E QL
Sbjct: 251 VDQSGLFLPSRDYYLNRTAN-EKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQL 309
Query: 321 ANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLAT 379
ANITV + D RRD +Y+K+++ +LQ + P + W L + + S+ E VV+
Sbjct: 310 ANITVPQ--DQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGM 367
Query: 380 DYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELA 438
DY+QQVS+LI T +L+NYL+W +V + L F A +L + + G+ K
Sbjct: 368 DYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRW 427
Query: 439 RVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAA 498
+ C+ + G ALG+LFV F SK + ++ +I+ + L +L WMD +TR A
Sbjct: 428 QTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQA 487
Query: 499 ARAKLQYMMVMVGYPDFLLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQE 557
A+ K + M+G+PDF+L+P +D Y+ +E+ E ++F+N+LN FS ++ ++R+
Sbjct: 488 AKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKP 547
Query: 558 VDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHG 617
+ W + PQ +NAYYLP KN++VFPAGILQ Y + P++LN+GGIG ++GHELTH
Sbjct: 548 PSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHA 607
Query: 618 YDDWGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADM 677
+DD G +YD+ GNL WW S + F C+ Y+ + V +R+NG+ TLGENIAD
Sbjct: 608 FDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADN 667
Query: 678 GGLKLAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKH 737
GGLK AY+AY+ W+R+HG E LP + T+ QLFF+ FAQ WC R +S + ++TD H
Sbjct: 668 GGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPH 727
Query: 738 APEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
+P +RVLG++S +F R F CP SPMNP C VW
Sbjct: 728 SPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
>gi|153945771 endothelin converting enzyme 2 isoform D [Homo
sapiens]
Length = 811
Score = 529 bits (1362), Expect = e-150
Identities = 267/681 (39%), Positives = 408/681 (59%), Gaps = 20/681 (2%)
Query: 103 KAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLR 162
+A R A + +LD + PC+DFY F+CGGW+RR+ +PD + + T ++ +QN+ L+
Sbjct: 143 EACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK 202
Query: 163 RLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGV 222
LL A++K + F+ SCL + IE LG +P+ ++IE GGW++ G
Sbjct: 203 HLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGP------ 256
Query: 223 AARWDLNR---LLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQ 279
WD + +L G Y A F++ +S D ++S+ VI++DQ GL LP R YL +
Sbjct: 257 ---WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 313
Query: 280 DEDSEKILAAYRVFMERVLSLLGA--DAVEQKAQEILQVEQQLANITVSEHDDLRRDVSS 337
+ EK+L AY +ME + LLG + ++ Q++L++E QLANITV + D RRD
Sbjct: 314 TAN-EKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQ--DQRRDEEK 370
Query: 338 MYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLATDYMQQVSQLIRSTPHRV 396
+Y+K+++ +LQ + P + W L + + S+ E VV+ DY+QQVS+LI T +
Sbjct: 371 IYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSI 430
Query: 397 LHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELARVCLGQANRHFGMALGA 455
L+NYL+W +V + L F A +L + + G+ K + C+ + G ALG+
Sbjct: 431 LNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGS 490
Query: 456 LFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDF 515
LFV F SK + ++ +I+ + L +L WMD +TR AA+ K + M+G+PDF
Sbjct: 491 LFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDF 550
Query: 516 LLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYY 574
+L+P +D Y+ +E+ E ++F+N+LN FS ++ ++R+ + W + PQ +NAYY
Sbjct: 551 ILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYY 610
Query: 575 LPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHW 634
LP KN++VFPAGILQ Y + P++LN+GGIG ++GHELTH +DD G +YD+ GNL W
Sbjct: 611 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 670
Query: 635 WTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYHAYQKWVREH 694
W S + F C+ Y+ + V +R+NG+ TLGENIAD GGLK AY+AY+ W+R+H
Sbjct: 671 WQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKH 730
Query: 695 GPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEF 754
G E LP + T+ QLFF+ FAQ WC R +S + ++TD H+P +RVLG++S +F
Sbjct: 731 GEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDF 790
Query: 755 GRAFHCPKDSPMNPAHKCSVW 775
R F CP SPMNP C VW
Sbjct: 791 LRHFGCPVGSPMNPGQLCEVW 811
>gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens]
Length = 736
Score = 529 bits (1362), Expect = e-150
Identities = 267/681 (39%), Positives = 408/681 (59%), Gaps = 20/681 (2%)
Query: 103 KAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLR 162
+A R A + +LD + PC+DFY F+CGGW+RR+ +PD + + T ++ +QN+ L+
Sbjct: 68 EACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK 127
Query: 163 RLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGV 222
LL A++K + F+ SCL + IE LG +P+ ++IE GGW++ G
Sbjct: 128 HLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGP------ 181
Query: 223 AARWDLNR---LLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQ 279
WD + +L G Y A F++ +S D ++S+ VI++DQ GL LP R YL +
Sbjct: 182 ---WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 238
Query: 280 DEDSEKILAAYRVFMERVLSLLGA--DAVEQKAQEILQVEQQLANITVSEHDDLRRDVSS 337
+ EK+L AY +ME + LLG + ++ Q++L++E QLANITV + D RRD
Sbjct: 239 TAN-EKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQ--DQRRDEEK 295
Query: 338 MYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLATDYMQQVSQLIRSTPHRV 396
+Y+K+++ +LQ + P + W L + + S+ E VV+ DY+QQVS+LI T +
Sbjct: 296 IYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSI 355
Query: 397 LHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELARVCLGQANRHFGMALGA 455
L+NYL+W +V + L F A +L + + G+ K + C+ + G ALG+
Sbjct: 356 LNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGS 415
Query: 456 LFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDF 515
LFV F SK + ++ +I+ + L +L WMD +TR AA+ K + M+G+PDF
Sbjct: 416 LFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDF 475
Query: 516 LLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYY 574
+L+P +D Y+ +E+ E ++F+N+LN FS ++ ++R+ + W + PQ +NAYY
Sbjct: 476 ILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYY 535
Query: 575 LPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHW 634
LP KN++VFPAGILQ Y + P++LN+GGIG ++GHELTH +DD G +YD+ GNL W
Sbjct: 536 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 595
Query: 635 WTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYHAYQKWVREH 694
W S + F C+ Y+ + V +R+NG+ TLGENIAD GGLK AY+AY+ W+R+H
Sbjct: 596 WQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKH 655
Query: 695 GPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEF 754
G E LP + T+ QLFF+ FAQ WC R +S + ++TD H+P +RVLG++S +F
Sbjct: 656 GEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDF 715
Query: 755 GRAFHCPKDSPMNPAHKCSVW 775
R F CP SPMNP C VW
Sbjct: 716 LRHFGCPVGSPMNPGQLCEVW 736
>gi|153945761 endothelin converting enzyme 2 isoform A [Homo
sapiens]
Length = 883
Score = 529 bits (1362), Expect = e-150
Identities = 267/681 (39%), Positives = 408/681 (59%), Gaps = 20/681 (2%)
Query: 103 KAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLR 162
+A R A + +LD + PC+DFY F+CGGW+RR+ +PD + + T ++ +QN+ L+
Sbjct: 215 EACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK 274
Query: 163 RLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGV 222
LL A++K + F+ SCL + IE LG +P+ ++IE GGW++ G
Sbjct: 275 HLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGP------ 328
Query: 223 AARWDLNR---LLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQ 279
WD + +L G Y A F++ +S D ++S+ VI++DQ GL LP R YL +
Sbjct: 329 ---WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 385
Query: 280 DEDSEKILAAYRVFMERVLSLLGA--DAVEQKAQEILQVEQQLANITVSEHDDLRRDVSS 337
+ EK+L AY +ME + LLG + ++ Q++L++E QLANITV + D RRD
Sbjct: 386 TAN-EKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQ--DQRRDEEK 442
Query: 338 MYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLATDYMQQVSQLIRSTPHRV 396
+Y+K+++ +LQ + P + W L + + S+ E VV+ DY+QQVS+LI T +
Sbjct: 443 IYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSI 502
Query: 397 LHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELARVCLGQANRHFGMALGA 455
L+NYL+W +V + L F A +L + + G+ K + C+ + G ALG+
Sbjct: 503 LNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGS 562
Query: 456 LFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDF 515
LFV F SK + ++ +I+ + L +L WMD +TR AA+ K + M+G+PDF
Sbjct: 563 LFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDF 622
Query: 516 LLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYY 574
+L+P +D Y+ +E+ E ++F+N+LN FS ++ ++R+ + W + PQ +NAYY
Sbjct: 623 ILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYY 682
Query: 575 LPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHW 634
LP KN++VFPAGILQ Y + P++LN+GGIG ++GHELTH +DD G +YD+ GNL W
Sbjct: 683 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 742
Query: 635 WTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYHAYQKWVREH 694
W S + F C+ Y+ + V +R+NG+ TLGENIAD GGLK AY+AY+ W+R+H
Sbjct: 743 WQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKH 802
Query: 695 GPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEF 754
G E LP + T+ QLFF+ FAQ WC R +S + ++TD H+P +RVLG++S +F
Sbjct: 803 GEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDF 862
Query: 755 GRAFHCPKDSPMNPAHKCSVW 775
R F CP SPMNP C VW
Sbjct: 863 LRHFGCPVGSPMNPGQLCEVW 883
>gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens]
Length = 779
Score = 477 bits (1228), Expect = e-134
Identities = 257/710 (36%), Positives = 397/710 (55%), Gaps = 36/710 (5%)
Query: 96 PEGCPERKAFAR---------AARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLT 146
P G PE + + AA + N+D + +PC DFY FACGGWLRRH IP+
Sbjct: 76 PRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSR 135
Query: 147 YGTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIE 206
Y + ++ E L+ +L A + K R +RSC++ IE+ G +P+L+++E
Sbjct: 136 YSIFDVLRDELEVILKAVLENSTAKDRPAVE-KARTLYRSCMNQSVIEKRGSQPLLDILE 194
Query: 207 DCGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQD 266
GGW + V W+L R L ++ L L + DD+NSSR++I IDQ
Sbjct: 195 VVGGWPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQP 254
Query: 267 GLTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADA--------VEQKAQEILQVEQ 318
L +P R Y + K+ AY FM V +LL DA V++ ++L++E
Sbjct: 255 TLGMPSREYYF-NGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 313
Query: 319 QLANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSE-------E 371
QLA TV + + R DV ++Y+++ L +LQ + W L Q S +
Sbjct: 314 QLAKATVPQEE--RHDVIALYHRMGLEELQSQFGLKGFNWTL--FIQTVLSSVKIKLLPD 369
Query: 372 EEVVLLATDYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGS 431
EEVV+ Y+Q + +I + R + NYLVWR+V+ LS F++ + + G+
Sbjct: 370 EEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGT 429
Query: 432 DKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWM 491
+ R C+G N + A+G+L+V E F SK+ V++L++ ++ + + L+EL WM
Sbjct: 430 MVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWM 489
Query: 492 DAETRAAARAKLQYMMVMVGYPDFLLKP--DAVDKEYE-FEVHEKTYFKNILNSIRFSIQ 548
D E++ A+ K + +G+PD++L+ +D+EY E YF+N L +++ Q
Sbjct: 490 DEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQ 549
Query: 549 LSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGT 608
S++K+R++VD + W++ +NA+Y PN+NQ+VFPAGILQP + + PQ+LN+GGIG
Sbjct: 550 RSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGM 609
Query: 609 IIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFT---VYNQRVN 665
+IGHE+THG+DD G +D++GN++ WW+ S F ++EC++ Y N++ Q VN
Sbjct: 610 VIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVN 669
Query: 666 GKHTLGENIADMGGLKLAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRS 725
G +TLGENIAD GG++ AY AY KW+ E G + LP L TH+QLFFI +AQ WC R
Sbjct: 670 GFNTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRP 729
Query: 726 QSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
+ + TD H+P YRVLGS+ F FHC + +PM+P +C VW
Sbjct: 730 EFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
>gi|116256333 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 443 bits (1140), Expect = e-124
Identities = 257/744 (34%), Positives = 390/744 (52%), Gaps = 38/744 (5%)
Query: 54 RWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLA 113
RW E+ L S LV + A+ L Y + C AAR L
Sbjct: 23 RWTPLEISL-SVLVLLLTIIAVTMIALYATYDDGI----------CKSSDCIKSAAR-LI 70
Query: 114 ANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPGGGPG 173
N+DA+ +PC DF+ +ACGGWL+R+ IP+ YG + ++ E L+ +L P
Sbjct: 71 QNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDI 130
Query: 174 GAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGVAARWDLNRLLY 233
A Q K +A +RSC++ I+ G P+L+++ D GW + A W + +
Sbjct: 131 VAVQ-KAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIA 189
Query: 234 KAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVF 293
+ Y L +L V DD+NS +VI IDQ L LP R Y E AY F
Sbjct: 190 QLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEAC-TAYVDF 248
Query: 294 MERVLSLLGADA--------VEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLG 345
M V L+ + + + +++++E+++AN T D R D +YNK+TL
Sbjct: 249 MISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED--RNDPMLLYNKMTLA 306
Query: 346 QLQKITP------HLRWKWLLDQIFQE---DFSEEEEVVLLATDYMQQVSQLIRSTPHRV 396
Q+Q W ++I + EE+VV+ A +Y+ ++ ++ R
Sbjct: 307 QIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARD 366
Query: 397 LHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQANRHFGMALGAL 456
L N + WR ++ L LS ++E+ + + + G+ R C N + A+G L
Sbjct: 367 LQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRL 426
Query: 457 FVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDFL 516
+V F+ SK V+ L+ I+ + Q L++L WMDAET+ A K + +GYPD +
Sbjct: 427 YVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDI 486
Query: 517 LKPD-AVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYY 574
+ D ++ EY E E YF+NI+ +++FS +KK+R++VDK W+ +NA+Y
Sbjct: 487 VSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFY 546
Query: 575 LPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHW 634
+NQ+VFPAGILQP + SLNYGGIG +IGHE+THG+DD G +++ G+L+ W
Sbjct: 547 SSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDW 606
Query: 635 WTEASYSRFLRKAECIVRLYDNFT---VYNQRVNGKHTLGENIADMGGLKLAYHAYQKWV 691
WT+ S S F +++C+V Y NF+ Q +NG +TLGENIAD GGL AY AYQ ++
Sbjct: 607 WTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYI 666
Query: 692 REHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQF 751
+++G E LP L H QLFF+ FAQ WC R + + TD H+P ++R++G++
Sbjct: 667 KKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 726
Query: 752 EEFGRAFHCPKDSPMNPAHKCSVW 775
EF AFHC K+S MNP KC VW
Sbjct: 727 AEFSEAFHCRKNSYMNPEKKCRVW 750
>gi|116256331 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 443 bits (1140), Expect = e-124
Identities = 257/744 (34%), Positives = 390/744 (52%), Gaps = 38/744 (5%)
Query: 54 RWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLA 113
RW E+ L S LV + A+ L Y + C AAR L
Sbjct: 23 RWTPLEISL-SVLVLLLTIIAVTMIALYATYDDGI----------CKSSDCIKSAAR-LI 70
Query: 114 ANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPGGGPG 173
N+DA+ +PC DF+ +ACGGWL+R+ IP+ YG + ++ E L+ +L P
Sbjct: 71 QNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDI 130
Query: 174 GAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGVAARWDLNRLLY 233
A Q K +A +RSC++ I+ G P+L+++ D GW + A W + +
Sbjct: 131 VAVQ-KAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIA 189
Query: 234 KAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVF 293
+ Y L +L V DD+NS +VI IDQ L LP R Y E AY F
Sbjct: 190 QLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEAC-TAYVDF 248
Query: 294 MERVLSLLGADA--------VEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLG 345
M V L+ + + + +++++E+++AN T D R D +YNK+TL
Sbjct: 249 MISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED--RNDPMLLYNKMTLA 306
Query: 346 QLQKITP------HLRWKWLLDQIFQE---DFSEEEEVVLLATDYMQQVSQLIRSTPHRV 396
Q+Q W ++I + EE+VV+ A +Y+ ++ ++ R
Sbjct: 307 QIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARD 366
Query: 397 LHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQANRHFGMALGAL 456
L N + WR ++ L LS ++E+ + + + G+ R C N + A+G L
Sbjct: 367 LQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRL 426
Query: 457 FVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDFL 516
+V F+ SK V+ L+ I+ + Q L++L WMDAET+ A K + +GYPD +
Sbjct: 427 YVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDI 486
Query: 517 LKPD-AVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYY 574
+ D ++ EY E E YF+NI+ +++FS +KK+R++VDK W+ +NA+Y
Sbjct: 487 VSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFY 546
Query: 575 LPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHW 634
+NQ+VFPAGILQP + SLNYGGIG +IGHE+THG+DD G +++ G+L+ W
Sbjct: 547 SSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDW 606
Query: 635 WTEASYSRFLRKAECIVRLYDNFT---VYNQRVNGKHTLGENIADMGGLKLAYHAYQKWV 691
WT+ S S F +++C+V Y NF+ Q +NG +TLGENIAD GGL AY AYQ ++
Sbjct: 607 WTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYI 666
Query: 692 REHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQF 751
+++G E LP L H QLFF+ FAQ WC R + + TD H+P ++R++G++
Sbjct: 667 KKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 726
Query: 752 EEFGRAFHCPKDSPMNPAHKCSVW 775
EF AFHC K+S MNP KC VW
Sbjct: 727 AEFSEAFHCRKNSYMNPEKKCRVW 750
>gi|116256327 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 443 bits (1140), Expect = e-124
Identities = 257/744 (34%), Positives = 390/744 (52%), Gaps = 38/744 (5%)
Query: 54 RWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLA 113
RW E+ L S LV + A+ L Y + C AAR L
Sbjct: 23 RWTPLEISL-SVLVLLLTIIAVTMIALYATYDDGI----------CKSSDCIKSAAR-LI 70
Query: 114 ANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPGGGPG 173
N+DA+ +PC DF+ +ACGGWL+R+ IP+ YG + ++ E L+ +L P
Sbjct: 71 QNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDI 130
Query: 174 GAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGVAARWDLNRLLY 233
A Q K +A +RSC++ I+ G P+L+++ D GW + A W + +
Sbjct: 131 VAVQ-KAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIA 189
Query: 234 KAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVF 293
+ Y L +L V DD+NS +VI IDQ L LP R Y E AY F
Sbjct: 190 QLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEAC-TAYVDF 248
Query: 294 MERVLSLLGADA--------VEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLG 345
M V L+ + + + +++++E+++AN T D R D +YNK+TL
Sbjct: 249 MISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED--RNDPMLLYNKMTLA 306
Query: 346 QLQKITP------HLRWKWLLDQIFQE---DFSEEEEVVLLATDYMQQVSQLIRSTPHRV 396
Q+Q W ++I + EE+VV+ A +Y+ ++ ++ R
Sbjct: 307 QIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARD 366
Query: 397 LHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQANRHFGMALGAL 456
L N + WR ++ L LS ++E+ + + + G+ R C N + A+G L
Sbjct: 367 LQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRL 426
Query: 457 FVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDFL 516
+V F+ SK V+ L+ I+ + Q L++L WMDAET+ A K + +GYPD +
Sbjct: 427 YVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDI 486
Query: 517 LKPD-AVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYY 574
+ D ++ EY E E YF+NI+ +++FS +KK+R++VDK W+ +NA+Y
Sbjct: 487 VSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFY 546
Query: 575 LPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHW 634
+NQ+VFPAGILQP + SLNYGGIG +IGHE+THG+DD G +++ G+L+ W
Sbjct: 547 SSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDW 606
Query: 635 WTEASYSRFLRKAECIVRLYDNFT---VYNQRVNGKHTLGENIADMGGLKLAYHAYQKWV 691
WT+ S S F +++C+V Y NF+ Q +NG +TLGENIAD GGL AY AYQ ++
Sbjct: 607 WTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYI 666
Query: 692 REHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQF 751
+++G E LP L H QLFF+ FAQ WC R + + TD H+P ++R++G++
Sbjct: 667 KKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 726
Query: 752 EEFGRAFHCPKDSPMNPAHKCSVW 775
EF AFHC K+S MNP KC VW
Sbjct: 727 AEFSEAFHCRKNSYMNPEKKCRVW 750
>gi|116256329 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 443 bits (1140), Expect = e-124
Identities = 257/744 (34%), Positives = 390/744 (52%), Gaps = 38/744 (5%)
Query: 54 RWNRREVCLLSGLVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLA 113
RW E+ L S LV + A+ L Y + C AAR L
Sbjct: 23 RWTPLEISL-SVLVLLLTIIAVTMIALYATYDDGI----------CKSSDCIKSAAR-LI 70
Query: 114 ANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARPGGGPG 173
N+DA+ +PC DF+ +ACGGWL+R+ IP+ YG + ++ E L+ +L P
Sbjct: 71 QNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPKTEDI 130
Query: 174 GAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGVAARWDLNRLLY 233
A Q K +A +RSC++ I+ G P+L+++ D GW + A W + +
Sbjct: 131 VAVQ-KAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIA 189
Query: 234 KAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVF 293
+ Y L +L V DD+NS +VI IDQ L LP R Y E AY F
Sbjct: 190 QLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEAC-TAYVDF 248
Query: 294 MERVLSLLGADA--------VEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLG 345
M V L+ + + + +++++E+++AN T D R D +YNK+TL
Sbjct: 249 MISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPED--RNDPMLLYNKMTLA 306
Query: 346 QLQKITP------HLRWKWLLDQIFQE---DFSEEEEVVLLATDYMQQVSQLIRSTPHRV 396
Q+Q W ++I + EE+VV+ A +Y+ ++ ++ R
Sbjct: 307 QIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARD 366
Query: 397 LHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQANRHFGMALGAL 456
L N + WR ++ L LS ++E+ + + + G+ R C N + A+G L
Sbjct: 367 LQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRL 426
Query: 457 FVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDFL 516
+V F+ SK V+ L+ I+ + Q L++L WMDAET+ A K + +GYPD +
Sbjct: 427 YVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDI 486
Query: 517 LKPD-AVDKEY-EFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYY 574
+ D ++ EY E E YF+NI+ +++FS +KK+R++VDK W+ +NA+Y
Sbjct: 487 VSNDNKLNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFY 546
Query: 575 LPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHW 634
+NQ+VFPAGILQP + SLNYGGIG +IGHE+THG+DD G +++ G+L+ W
Sbjct: 547 SSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDW 606
Query: 635 WTEASYSRFLRKAECIVRLYDNFT---VYNQRVNGKHTLGENIADMGGLKLAYHAYQKWV 691
WT+ S S F +++C+V Y NF+ Q +NG +TLGENIAD GGL AY AYQ ++
Sbjct: 607 WTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYI 666
Query: 692 REHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQF 751
+++G E LP L H QLFF+ FAQ WC R + + TD H+P ++R++G++
Sbjct: 667 KKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNS 726
Query: 752 EEFGRAFHCPKDSPMNPAHKCSVW 775
EF AFHC K+S MNP KC VW
Sbjct: 727 AEFSEAFHCRKNSYMNPEKKCRVW 750
>gi|90403592 phosphate-regulating neutral endopeptidase [Homo
sapiens]
Length = 749
Score = 374 bits (959), Expect = e-103
Identities = 231/733 (31%), Positives = 390/733 (53%), Gaps = 29/733 (3%)
Query: 66 LVFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARAARFLAANLDASIDPCQD 125
LV G +L +L L G ++ A E C + + AA L+ ++ S+DPC +
Sbjct: 23 LVVFVGGTLVLGTILFLVSQGLLSLQ--AKQEYCLKPECIEAAAAILS-KVNLSVDPCDN 79
Query: 126 FYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLRRLLARP-GGGPGGAAQRKVRAFF 184
F+ FAC GW+ + IP+D +YG + + +L+ LL + A +K + +
Sbjct: 80 FFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKELLEKSISRRRDTEAIQKAKILY 139
Query: 185 RSCLDMREIERLGPRPMLEVIEDCG-GWDLGGAEERP-GVAA--RWDLNRLLYKAQGVYS 240
SC++ + IE+ +P+L ++ W + + P GV + ++ L + L +G YS
Sbjct: 140 SSCMNEKAIEKADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKFSLLQTLATFRGQYS 199
Query: 241 AAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQDEDSEKILAAYRVFMERVLSL 300
+ L VS DD+ S+ +++++DQ L+L R YL +++ A FM L
Sbjct: 200 NSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVL 259
Query: 301 LGADA--VEQKAQEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKW 358
LGA++ E + +L++E ++A I + + R +MYNK+ + +L + P W
Sbjct: 260 LGANSSRAEHDMKSVLRLEIKIAEIMIPHEN---RTSEAMYNKMNISELSAMIPQFDWLG 316
Query: 359 LLDQIFQ-------EDFSEEEEVVLLATDYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSE 411
+ ++ +D S E VV+ Y + + +++ S + + NYLVWR+V
Sbjct: 317 YIKKVIDTRLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIP 376
Query: 412 HLSPPFREALHELAQEMEGSDKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQ 471
+LS F+ E ++ ++G+ C+ +G +FV +F K ++
Sbjct: 377 NLSRRFQYRWLEFSRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEMME 436
Query: 472 QLVEDIKYILGQRLE-ELDWMDAETRAAARAKLQYMMVMVGYPDFLLKPDAVDKEYE-FE 529
+LVE +++ LE E +WMDA T+ A+ K + ++ VGYP+F++ V+++ + +
Sbjct: 437 ELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTHVNEDLKAIK 496
Query: 530 VHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQ 589
E YF N+L + ++ Q +R+ V K+ W P +NA+Y + NQ+ FPAG LQ
Sbjct: 497 FSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQ 556
Query: 590 -PTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLRKAE 648
P + ++P+SL+YG IG I+GHE THG+D+ G +YD++GNL WW+ S +F K +
Sbjct: 557 KPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTK 616
Query: 649 CIVRLYDNF--TVYNQRVNGKHTLGENIADMGGLKLAYHAYQKWV--REHGPEHP-LPRL 703
C++ Y N+ V GK TLGENIAD GGL+ A+ AY+KW+ R G E P LP +
Sbjct: 617 CMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLPGI 676
Query: 704 KYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKD 763
+T++QLFF+++A C R ++ QV H+P +RV G++S FEEF +AF+CP +
Sbjct: 677 TFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPPN 736
Query: 764 SPMNPA-HKCSVW 775
S MN C +W
Sbjct: 737 STMNRGMDSCRLW 749
>gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens]
Length = 732
Score = 278 bits (710), Expect = 2e-74
Identities = 200/697 (28%), Positives = 330/697 (47%), Gaps = 55/697 (7%)
Query: 96 PEGCPERKAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGE 155
P C +LA+ + S+ PC DF+SFACG K T + +
Sbjct: 74 PRPCETSVCLDLRDHYLASG-NTSVAPCTDFFSFACGR---------AKETNNSFQELAT 123
Query: 156 QNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGG 215
+N+ RLRR+L G+ + K F+ SC+D IE G P+ +VIE+ GGW + G
Sbjct: 124 KNKNRLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRISG 183
Query: 216 AEERPGVAARW---DLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPE 272
+W + NR L Y F + + VI+IDQ PE
Sbjct: 184 ---------KWTSLNFNRTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQ-----PE 229
Query: 273 RTLYLAQDEDSE---KILAAYRVFMERVLSLLGADAVEQKAQEILQVEQQLANITVSEHD 329
+ L QD++ + +I Y ++ ++ +LLG D + + L +
Sbjct: 230 FDVPLKQDQEQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPL 289
Query: 330 DLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLATDYMQQVSQL 388
+ RR ++ VT+ QL+++ P + W L F S + +V+ +Y++ +SQL
Sbjct: 290 EQRRAQGKLFQMVTIDQLKEMAPAIDWLSCLQATFTPMSLSPSQSLVVHDVEYLKNMSQL 349
Query: 389 IRST---PHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEM-EGSDKPQELARV---- 440
+ L ++++ +VV LS L F+EA +L+Q++ E +++P AR
Sbjct: 350 VEEMLLKQRDFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMK 409
Query: 441 CLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAAR 500
C+ + F L ALFV E F ++++ +L I+ L RL L WM+ ET+ A+
Sbjct: 410 CVEETGTFFEPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQ 469
Query: 501 AKLQYMMVMVGYPDFLLKPDAVDKEYEFEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDK 560
K+ + V +G ++ LKP+ +EY ++ +++L+ +R V+ Q +
Sbjct: 470 DKVAQLQVEMGASEWALKPELARQEYNDIQLGSSFLQSVLSCVRSLRARIVQSFLQPHPQ 529
Query: 561 STWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDD 620
W + P +NAYY + + +VFPAG+LQP + P +P+++N+G G+I+ HEL H +
Sbjct: 530 HRWKVSPWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIFYQ 589
Query: 621 WGGQYDRSGNLLHWWTEASYSRFLRKAE-CIVRLYDNFTVYNQ-RVNGKHTLGENIADMG 678
LL A + L++A C+ R Y F + ++ N T EN AD+G
Sbjct: 590 L---------LLPGGCLACDNHALQEAHLCLKRHYAAFPLPSRTSFNDSLTFLENAADVG 640
Query: 679 GLKLAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHA 738
GL +A AY K + H E LP L + Q+FF ++AQ C K Q + D H+
Sbjct: 641 GLAIALQAYSKRLLRHHGETVLPSLDLSPQQIFFRSYAQVMCRKPSPQDSH-----DTHS 695
Query: 739 PEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
P H RV G +S F R F C + + +NP+ +C +W
Sbjct: 696 PPHLRVHGPLSSTPAFARYFRCARGALLNPSSRCQLW 732
>gi|239753431 PREDICTED: similar to endothelin converting
enzyme-like 1 [Homo sapiens]
Length = 97
Score = 114 bits (286), Expect = 3e-25
Identities = 60/79 (75%), Positives = 62/79 (78%), Gaps = 6/79 (7%)
Query: 392 TPH------RVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQA 445
TPH RVLHNYLVW VVVVLSEHL PF E LH+LAQEMEGS K QELARV LGQA
Sbjct: 5 TPHWLHLAPRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGKLQELARVSLGQA 64
Query: 446 NRHFGMALGALFVHEHFSA 464
N H+GMAL ALFVHEH SA
Sbjct: 65 NHHYGMALRALFVHEHLSA 83
>gi|239747995 PREDICTED: hypothetical protein XP_002346505 [Homo
sapiens]
Length = 97
Score = 114 bits (286), Expect = 3e-25
Identities = 60/79 (75%), Positives = 62/79 (78%), Gaps = 6/79 (7%)
Query: 392 TPH------RVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQA 445
TPH RVLHNYLVW VVVVLSEHL PF E LH+LAQEMEGS K QELARV LGQA
Sbjct: 5 TPHWLHLAPRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGKLQELARVSLGQA 64
Query: 446 NRHFGMALGALFVHEHFSA 464
N H+GMAL ALFVHEH SA
Sbjct: 65 NHHYGMALRALFVHEHLSA 83
>gi|239741893 PREDICTED: hypothetical protein XP_002342317 [Homo
sapiens]
Length = 97
Score = 114 bits (286), Expect = 3e-25
Identities = 60/79 (75%), Positives = 62/79 (78%), Gaps = 6/79 (7%)
Query: 392 TPH------RVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKPQELARVCLGQA 445
TPH RVLHNYLVW VVVVLSEHL PF E LH+LAQEMEGS K QELARV LGQA
Sbjct: 5 TPHWLHLAPRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGKLQELARVSLGQA 64
Query: 446 NRHFGMALGALFVHEHFSA 464
N H+GMAL ALFVHEH SA
Sbjct: 65 NHHYGMALRALFVHEHLSA 83
>gi|239740948 PREDICTED: hypothetical protein LOC644246 [Homo
sapiens]
Length = 328
Score = 36.2 bits (82), Expect = 0.12
Identities = 30/77 (38%), Positives = 36/77 (46%), Gaps = 10/77 (12%)
Query: 154 GEQNEERLRRL-LARPGGGPGGA-------AQRKVRAFFRSCLDMREIERLGPRPMLEVI 205
GE+ ++RLRRL L RP G PGGA A R+ R F S R PR +
Sbjct: 252 GEEGQQRLRRLRLRRPRGPPGGAAAAASVMAPRRSRCFCTSICGGRGARPQLPRTCGDGT 311
Query: 206 EDCGGWD--LGGAEERP 220
+ CG L AEE P
Sbjct: 312 QHCGRGKPALAAAEEWP 328
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 33.1 bits (74), Expect = 1.0
Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
Query: 356 WKWLLDQIFQEDFSEEEEVVLLATDYMQQVSQLIR-STPHRVLHNYLVWRVVVVLSEHLS 414
WK+ + +E + E+E +L + DY + ++ ++R + HR + + R S H
Sbjct: 628 WKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGR-----SGHFE 682
Query: 415 PPFREALHELAQEMEGSDKPQE 436
+E +A+E GS+K +E
Sbjct: 683 QAIKEGEDMIAEEHFGSEKIRE 704
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 33.1 bits (74), Expect = 1.0
Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
Query: 356 WKWLLDQIFQEDFSEEEEVVLLATDYMQQVSQLIR-STPHRVLHNYLVWRVVVVLSEHLS 414
WK+ + +E + E+E +L + DY + ++ ++R + HR + + R S H
Sbjct: 641 WKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGR-----SGHFE 695
Query: 415 PPFREALHELAQEMEGSDKPQE 436
+E +A+E GS+K +E
Sbjct: 696 QAIKEGEDMIAEEHFGSEKIRE 717
>gi|56699473 zinc finger protein 192 [Homo sapiens]
Length = 578
Score = 32.3 bits (72), Expect = 1.7
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 3/126 (2%)
Query: 311 QEILQVEQQLANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSE 370
QE L + L + H LR D+++ + L L++ L + L + +
Sbjct: 60 QETLGPREALIQLRALCHQWLRPDLNTKEQILELLVLEQFLTILPEE-LQTLVKEHQLEN 118
Query: 371 EEEVVLLATDYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEG 430
EEVV L D +Q+ L R RV + ++W VV + PP + E Q
Sbjct: 119 GEEVVTLLEDLERQIDILGRPVSARVHGHRVLWEEVVHSASAPEPPNTQLQSEATQHK-- 176
Query: 431 SDKPQE 436
S PQE
Sbjct: 177 SPVPQE 182
>gi|239744421 PREDICTED: hypothetical protein [Homo sapiens]
Length = 252
Score = 31.2 bits (69), Expect = 3.8
Identities = 46/161 (28%), Positives = 58/161 (36%), Gaps = 32/161 (19%)
Query: 23 CGAGGARGASLPP-GFPLG--AARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAM 79
C GG RG S P G LG + R G S LP + G +
Sbjct: 112 CLWGGERGQSPPELGSDLGPQSRRRPPGVTSSLPSLDS----------LGPGCTGVAQRT 161
Query: 80 LALKYLGPVAAGGGACPEGCPERKAFARA------ARFLAANLDASIDPCQDFYSFACGG 133
++ G GGA P+G P +A R +L D S Q +S G
Sbjct: 162 ---RHAGGRHRPGGAAPQGSPHSRALCRVVGDHLLGSWLITGKDGSTQGLQQLWS--PGP 216
Query: 134 WLRRHAIPDDKLTYGTIAAIGEQN-EERLRRLLARPGGGPG 173
+R A P GT +GE EER+R L P PG
Sbjct: 217 RIRHPAAPQ-----GTQKGLGEDAFEERVR--LVHPPPAPG 250
>gi|6631102 protocadherin 8 isoform 1 precursor [Homo sapiens]
Length = 1070
Score = 31.2 bits (69), Expect = 3.8
Identities = 28/98 (28%), Positives = 37/98 (37%), Gaps = 18/98 (18%)
Query: 25 AGGARGASLPPGFPLGAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAML---- 80
AGG RG + P G+R G+ + L ++ AG C +L A +
Sbjct: 712 AGGGRGPAAPASAGSPERSRPPGSRLGVSGSVLQWDTPLIVIIVLAGSCTLLLAAIIAIA 771
Query: 81 --------------ALKYLGPVAAGGGACPEGCPERKA 104
AL+ P AAGGGA G PE A
Sbjct: 772 TTCNRRKKEVRKGGALREERPGAAGGGASAPGSPEEAA 809
>gi|30039692 NIMA-related kinase 8 [Homo sapiens]
Length = 692
Score = 30.8 bits (68), Expect = 5.0
Identities = 32/108 (29%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 26 GGARGASLPPGFPLGAARSATGARSGLPRWNRREVCLLSGLVFAAGLCAILAAMLALKYL 85
G R A PP + A G LP N V + +G AG+ + L L
Sbjct: 301 GPVRPAIPPPLSSVYAWGGGLGTPLRLPMLNTEVVQVAAGRTQKAGVTR--SGRLILWEA 358
Query: 86 GPVAAGGGACPEGCPERKAFARAARFLAANLDASID--PCQDFYSFAC 131
P+ AGGG+ G E+ +RFL +I C DF++ AC
Sbjct: 359 PPLGAGGGSLLPGAVEQPQPQFISRFLEGQSGVTIKHVACGDFFT-AC 405
>gi|158937236 aminopeptidase puromycin sensitive [Homo sapiens]
Length = 919
Score = 30.8 bits (68), Expect = 5.0
Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 22/92 (23%)
Query: 592 LYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNL--LHWWTE-------ASYSR 642
L DP S + + ++GHEL H + GNL + WWT AS+
Sbjct: 332 LIDPKNSCSSSRQWVALVVGHELAHQW---------FGNLVTMEWWTHLWLNEGFASWIE 382
Query: 643 FLRKAECIVRLYDNFTVYNQRVNGKHTLGENI 674
+L C+ + + ++ Q V+ +T + +
Sbjct: 383 YL----CVDHCFPEYDIWTQFVSADYTRAQEL 410
>gi|33188461 GATA binding protein 4 [Homo sapiens]
Length = 442
Score = 30.4 bits (67), Expect = 6.5
Identities = 25/102 (24%), Positives = 38/102 (37%), Gaps = 10/102 (9%)
Query: 17 VKYVSRCGAGGARGASLPPGFPLGAARSATGARSGLPRWNRR----------EVCLLSGL 66
+ Y+ GAG A G + A+ + G + G P W++ V
Sbjct: 51 LSYLQGGGAGSASGGASGGSSGGAASGAGPGTQQGSPGWSQAGADGAAYTPPPVSPRFSF 110
Query: 67 VFAAGLCAILAAMLALKYLGPVAAGGGACPEGCPERKAFARA 108
G A AA A + ++GGGA G R+ + RA
Sbjct: 111 PGTTGSLAAAAAAAAAREAAAYSSGGGAAGAGLAGREQYGRA 152
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 30.4 bits (67), Expect = 6.5
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 9/85 (10%)
Query: 24 GAGGARGASL--------PPGFPLGAARSATGARSGLPRWNRREVCLL-SGLVFAAGLCA 74
G GG G L PP PL A A PR++ + L + +V AA L A
Sbjct: 272 GGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSA 331
Query: 75 ILAAMLALKYLGPVAAGGGACPEGC 99
A++ G GGG GC
Sbjct: 332 AAASLSVAAASGGAGTGGGGAGGGC 356
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 30.4 bits (67), Expect = 6.5
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 9/85 (10%)
Query: 24 GAGGARGASL--------PPGFPLGAARSATGARSGLPRWNRREVCLL-SGLVFAAGLCA 74
G GG G L PP PL A A PR++ + L + +V AA L A
Sbjct: 272 GGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSA 331
Query: 75 ILAAMLALKYLGPVAAGGGACPEGC 99
A++ G GGG GC
Sbjct: 332 AAASLSVAAASGGAGTGGGGAGGGC 356
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,905,834
Number of Sequences: 37866
Number of extensions: 1435228
Number of successful extensions: 4029
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3906
Number of HSP's gapped (non-prelim): 45
length of query: 775
length of database: 18,247,518
effective HSP length: 110
effective length of query: 665
effective length of database: 14,082,258
effective search space: 9364701570
effective search space used: 9364701570
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.