Guide to the Human Genome
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Search of human proteins with 156630995

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156630995 neurotrophin 3 isoform 1 preproprotein [Homo
sapiens]
         (270 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156630995 neurotrophin 3 isoform 1 preproprotein [Homo sapiens]    546   e-156
gi|4505469 neurotrophin 3 isoform 2 preproprotein [Homo sapiens]      523   e-149
gi|70995319 nerve growth factor, beta polypeptide precursor [Hom...   183   2e-46
gi|219842298 brain-derived neurotrophic factor isoform e [Homo s...   172   3e-43
gi|219842314 brain-derived neurotrophic factor isoform a preprop...   172   4e-43
gi|219842312 brain-derived neurotrophic factor isoform a preprop...   172   4e-43
gi|219842309 brain-derived neurotrophic factor isoform a preprop...   172   4e-43
gi|219842306 brain-derived neurotrophic factor isoform a preprop...   172   4e-43
gi|219842303 brain-derived neurotrophic factor isoform a preprop...   172   4e-43
gi|219842300 brain-derived neurotrophic factor isoform a preprop...   172   4e-43
gi|219842296 brain-derived neurotrophic factor isoform d preprop...   172   4e-43
gi|219842294 brain-derived neurotrophic factor isoform a preprop...   172   4e-43
gi|219842292 brain-derived neurotrophic factor isoform a preprop...   172   4e-43
gi|219842290 brain-derived neurotrophic factor isoform a preprop...   172   4e-43
gi|219842288 brain-derived neurotrophic factor isoform a preprop...   172   4e-43
gi|25306264 brain-derived neurotrophic factor isoform a prepropr...   172   4e-43
gi|25306261 brain-derived neurotrophic factor isoform c prepropr...   172   4e-43
gi|25306267 brain-derived neurotrophic factor isoform a prepropr...   172   4e-43
gi|25306257 brain-derived neurotrophic factor isoform a prepropr...   172   4e-43
gi|25306253 brain-derived neurotrophic factor isoform a prepropr...   172   4e-43
gi|25306235 brain-derived neurotrophic factor isoform b prepropr...   172   4e-43
gi|5453808 neurotrophin 5 preproprotein [Homo sapiens]                167   9e-42
gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]            32   0.76 
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap...    32   0.76 
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap...    32   0.76 
gi|31581524 cordon-bleu homolog [Homo sapiens]                         30   2.2  
gi|46276868 hypothetical protein LOC9710 [Homo sapiens]                30   2.9  
gi|169160953 PREDICTED: hypothetical LOC644006 [Homo sapiens]          29   3.8  
gi|40789270 zinc finger protein 573 [Homo sapiens]                     29   3.8  
gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13...    28   6.5  

>gi|156630995 neurotrophin 3 isoform 1 preproprotein [Homo sapiens]
          Length = 270

 Score =  546 bits (1407), Expect = e-156
 Identities = 270/270 (100%), Positives = 270/270 (100%)

Query: 1   MVTFATILQVNKVMSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNK 60
           MVTFATILQVNKVMSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNK
Sbjct: 1   MVTFATILQVNKVMSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNK 60

Query: 61  LSKQMVDVKENYQSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLS 120
           LSKQMVDVKENYQSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLS
Sbjct: 61  LSKQMVDVKENYQSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLS 120

Query: 121 DSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAID 180
           DSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAID
Sbjct: 121 DSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAID 180

Query: 181 IRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRAL 240
           IRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRAL
Sbjct: 181 IRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRAL 240

Query: 241 TSENNKLVGWRWIRIDTSCVCALSRKIGRT 270
           TSENNKLVGWRWIRIDTSCVCALSRKIGRT
Sbjct: 241 TSENNKLVGWRWIRIDTSCVCALSRKIGRT 270


>gi|4505469 neurotrophin 3 isoform 2 preproprotein [Homo sapiens]
          Length = 257

 Score =  523 bits (1346), Expect = e-149
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 14  MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ 73
           MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ
Sbjct: 1   MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ 60

Query: 74  STLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLM 133
           STLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLM
Sbjct: 61  STLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLM 120

Query: 134 EDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIK 193
           EDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIK
Sbjct: 121 EDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIK 180

Query: 194 TGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWI 253
           TGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWI
Sbjct: 181 TGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWI 240

Query: 254 RIDTSCVCALSRKIGRT 270
           RIDTSCVCALSRKIGRT
Sbjct: 241 RIDTSCVCALSRKIGRT 257


>gi|70995319 nerve growth factor, beta polypeptide precursor [Homo
           sapiens]
          Length = 241

 Score =  183 bits (464), Expect = 2e-46
 Identities = 110/258 (42%), Positives = 148/258 (57%), Gaps = 21/258 (8%)

Query: 14  MSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSKQMVDVKENYQ 73
           MS+LFY +  A+L GIQ     + ++P          + QA   K         ++ +  
Sbjct: 1   MSMLFYTLITAFLIGIQAEPHSESNVPAGHT------IPQAHWTK---------LQHSLD 45

Query: 74  STLPKAEAPREPERGGPAKSAFQPV-IAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYL 132
           + L +A +   P     A+ A Q   I +D  L ++ RR  SPRVL S   P E      
Sbjct: 46  TALRRARSA--PAAAIAARVAGQTRNITVDPRLFKK-RRLRSPRVLFSTQPPREAADTQD 102

Query: 133 MEDYVGSPVVANRTSRRKRYAEHKS-HRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGE 191
           ++  VG     NRT R KR + H   HRGE+SVCDS S+WV DK++A DI+G +V VLGE
Sbjct: 103 LDFEVGGAAPFNRTHRSKRSSSHPIFHRGEFSVCDSVSVWVGDKTTATDIKGKEVMVLGE 162

Query: 192 IKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWR 251
           +   NS  KQYF+ET+C++  PV +GCRGID KHWNS C T+ T+V+ALT +  K   WR
Sbjct: 163 VNINNSVFKQYFFETKCRDPNPVDSGCRGIDSKHWNSYCTTTHTFVKALTMD-GKQAAWR 221

Query: 252 WIRIDTSCVCALSRKIGR 269
           +IRIDT+CVC LSRK  R
Sbjct: 222 FIRIDTACVCVLSRKAVR 239


>gi|219842298 brain-derived neurotrophic factor isoform e [Homo
           sapiens]
          Length = 329

 Score =  172 bits (436), Expect = 3e-43
 Identities = 106/281 (37%), Positives = 154/281 (54%), Gaps = 39/281 (13%)

Query: 4   FATILQVNKVMSILFYVIFLAYLRGIQGNNMDQRSLPEDSLNSLIIKLIQADILKNKLSK 63
           F    QV +VM+ILF  + ++Y   ++   M + ++                  + +   
Sbjct: 73  FIKFHQVRRVMTILFLTMVISYFGCMKAAPMKEANI------------------RGQGGL 114

Query: 64  QMVDVKENYQSTLPKAEAPREPERGGPAKS-AFQPVIAMDTELLRQQRRYN--------- 113
               V+ +   TL     P+   RG  + +  F+ VI    ELL + ++           
Sbjct: 115 AYPGVRTH--GTLESVNGPKAGSRGLTSLADTFEHVIE---ELLDEDQKVRPNEENNKDA 169

Query: 114 ---SPRVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESL 170
              + RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S 
Sbjct: 170 DLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISE 228

Query: 171 WVT--DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNS 228
           WVT  DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNS
Sbjct: 229 WVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNS 288

Query: 229 QCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           QC+T+Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 289 QCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 329


>gi|219842314 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842312 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842309 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842306 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842303 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842300 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842296 brain-derived neurotrophic factor isoform d
           preproprotein [Homo sapiens]
          Length = 276

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 122 RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 180

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 181 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 240

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 241 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 276


>gi|219842294 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842292 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842290 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|219842288 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|25306264 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|25306261 brain-derived neurotrophic factor isoform c
           preproprotein [Homo sapiens]
          Length = 262

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 108 RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 166

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 167 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 226

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 227 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 262


>gi|25306267 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|25306257 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|25306253 brain-derived neurotrophic factor isoform a
           preproprotein [Homo sapiens]
          Length = 247

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 93  RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 151

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 152 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 211

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 212 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 247


>gi|25306235 brain-derived neurotrophic factor isoform b
           preproprotein [Homo sapiens]
          Length = 255

 Score =  172 bits (435), Expect = 4e-43
 Identities = 84/156 (53%), Positives = 110/156 (70%), Gaps = 3/156 (1%)

Query: 116 RVLLSDSTPLEPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVT-- 173
           RV+LS   PLEPP L+L+E+Y      AN + R +R+++  + RGE SVCDS S WVT  
Sbjct: 101 RVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSD-PARRGELSVCDSISEWVTAA 159

Query: 174 DKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
           DK +A+D+ G  VTVL ++      +KQYFYET+C      K GCRGID +HWNSQC+T+
Sbjct: 160 DKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTT 219

Query: 234 QTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGR 269
           Q+YVRALT ++ K +GWR+IRIDTSCVC L+ K GR
Sbjct: 220 QSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR 255


>gi|5453808 neurotrophin 5 preproprotein [Homo sapiens]
          Length = 210

 Score =  167 bits (423), Expect = 9e-42
 Identities = 91/201 (45%), Positives = 120/201 (59%), Gaps = 22/201 (10%)

Query: 82  PREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYLME-----DY 136
           P  P    P  S   P +A + +LL       SPRV+LS   P  PP L+L+E     + 
Sbjct: 18  PSVPIESQPPPSTLPPFLAPEWDLL-------SPRVVLSRGAPAGPPLLFLLEAGAFRES 70

Query: 137 VGSPVVANRTSRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKT-G 195
            G+P  ANR+ R        S RGE +VCD+ S WVTD+ +A+D+RG +V VLGE+   G
Sbjct: 71  AGAP--ANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAG 128

Query: 196 NSPVKQYFYETRCKEARPVKNG-------CRGIDDKHWNSQCKTSQTYVRALTSENNKLV 248
            SP++QYF+ETRCK     + G       CRG+D +HW S+CK  Q+YVRALT++    V
Sbjct: 129 GSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRV 188

Query: 249 GWRWIRIDTSCVCALSRKIGR 269
           GWRWIRIDT+CVC L  + GR
Sbjct: 189 GWRWIRIDTACVCTLLSRTGR 209


>gi|38787935 BMP-2 inducible kinase isoform a [Homo sapiens]
          Length = 1161

 Score = 31.6 bits (70), Expect = 0.76
 Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 7/116 (6%)

Query: 91  AKSAFQPVIAMDTELLRQQR---RYNSPRVLLSDSTPLEPPPLYLMEDYVGSPVVANRTS 147
           +K   + ++  + +LLR  R   R +S + + S S P   PP    ED  GS    + + 
Sbjct: 633 SKLTEEELLDREFDLLRSNRLEERASSDKNVDSLSAPHNHPP----EDPFGSVPFISHSG 688

Query: 148 RRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYF 203
             ++ AEH S   E    +      T  +S     G + +V G+++ GN   +  F
Sbjct: 689 SPEKKAEHSSINQENGTANPIKNGKTSPASKDQRTGKKTSVQGQVQKGNDESESDF 744


>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo
           sapiens]
          Length = 3667

 Score = 31.6 bits (70), Expect = 0.76
 Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 126 EPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGE-YSVCDSESLWVTDKSSAIDIRGH 184
           EPP ++L    +  P+++N+   R  +    +HR   +S     S  +T  +S  ++  H
Sbjct: 261 EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEH 320

Query: 185 QVTVLGEIKTGNSP 198
             T  G I   ++P
Sbjct: 321 NRTTTGAIAVASTP 334


>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo
           sapiens]
          Length = 3707

 Score = 31.6 bits (70), Expect = 0.76
 Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 1/74 (1%)

Query: 126 EPPPLYLMEDYVGSPVVANRTSRRKRYAEHKSHRGE-YSVCDSESLWVTDKSSAIDIRGH 184
           EPP ++L    +  P+++N+   R  +    +HR   +S     S  +T  +S  ++  H
Sbjct: 301 EPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEH 360

Query: 185 QVTVLGEIKTGNSP 198
             T  G I   ++P
Sbjct: 361 NRTTTGAIAVASTP 374


>gi|31581524 cordon-bleu homolog [Homo sapiens]
          Length = 1261

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 18/78 (23%), Positives = 36/78 (46%), Gaps = 13/78 (16%)

Query: 73  QSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQRRYNSPRVLLSDSTPLEPPPLYL 132
           +S + K  AP  P  G P +      +++ +++  Q+++  +P    +   P  PPP   
Sbjct: 294 KSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAP----APPPPQPPPP--- 346

Query: 133 MEDYVGSPVVANRTSRRK 150
                 SP++ NRT  ++
Sbjct: 347 ------SPLIPNRTEDKE 358


>gi|46276868 hypothetical protein LOC9710 [Homo sapiens]
          Length = 1070

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 1/70 (1%)

Query: 61  LSKQMVDVKENYQSTLPKAEAPREPERGGPAKSAFQPVIAMDTELLRQQR-RYNSPRVLL 119
           +++Q     +  Q +LP    PR P+ G       QP +A   +  +QQ+ +    + LL
Sbjct: 679 VTEQKAGAMQPQQPSLPVPPPPRAPQAGAHTPLTPQPGLAPQQQSPKQQQPQVQYYQHLL 738

Query: 120 SDSTPLEPPP 129
               P +PPP
Sbjct: 739 QPIGPQQPPP 748


>gi|169160953 PREDICTED: hypothetical LOC644006 [Homo sapiens]
          Length = 190

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 7/91 (7%)

Query: 27  RGIQGNNMDQRSLPEDSLNSLIIKLIQA------DILKNKLSKQMVDVKENYQSTL-PKA 79
           R  Q    +  S PE SL +  I+L++       D+    L   +VD+  N    +  K 
Sbjct: 14  RQAQKRTREATSTPEISLEAEPIELVETAGDEIVDLTCESLEPVVVDLTHNDSVVIVDKR 73

Query: 80  EAPREPERGGPAKSAFQPVIAMDTELLRQQR 110
             PR   R  P   A   +++ D ELL + R
Sbjct: 74  RRPRRNARRLPQDHADSSMVSSDDELLSRDR 104


>gi|40789270 zinc finger protein 573 [Homo sapiens]
          Length = 607

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 31/112 (27%), Positives = 44/112 (39%), Gaps = 30/112 (26%)

Query: 147 SRRKRYAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYET 206
           SRR    EH    G++     E  ++ +K      RGHQ+TV   + TG  P     YE 
Sbjct: 226 SRRSNLVEH----GQFHT--DEKPYICEKCGKAFRRGHQLTVHQRVHTGKKP-----YE- 273

Query: 207 RCKEA-------------RPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENN 245
            CKE              + +  G +  + K    +CK + T  R LT   N
Sbjct: 274 -CKECGKGYTTASYFLLHQRIHKGGKPYECK----ECKKTFTLYRNLTRHQN 320


>gi|31657092 ATP binding cassette, sub-family A (ABC1), member 13
            [Homo sapiens]
          Length = 5058

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 20/76 (26%), Positives = 38/76 (50%), Gaps = 5/76 (6%)

Query: 176  SSAIDIRGH-QVTVLGEIKTGNSPV-KQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTS 233
            S+A+ + G   + +L E  +G  P  K+Y ++T  KE   V+ GC  +   H   +C+  
Sbjct: 4866 STALALVGKPDILLLDEPSSGMDPCSKRYLWQTIMKE---VREGCAAVLTSHSMEECEAL 4922

Query: 234  QTYVRALTSENNKLVG 249
             T +  + + + K +G
Sbjct: 4923 CTRLAIMVNGSFKCLG 4938


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,448,147
Number of Sequences: 37866
Number of extensions: 474387
Number of successful extensions: 1428
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1356
Number of HSP's gapped (non-prelim): 49
length of query: 270
length of database: 18,247,518
effective HSP length: 101
effective length of query: 169
effective length of database: 14,423,052
effective search space: 2437495788
effective search space used: 2437495788
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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