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Search of human proteins with 156151377
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens]
(207 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens] 398 e-111
gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens] 392 e-109
gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens] 185 3e-47
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens] 45 3e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 44 1e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 44 1e-04
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 43 2e-04
gi|42794779 myosin 18A isoform b [Homo sapiens] 42 3e-04
gi|28416946 myosin 18A isoform a [Homo sapiens] 42 3e-04
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 42 4e-04
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 42 5e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 42 5e-04
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 41 6e-04
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 41 6e-04
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 41 6e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 41 6e-04
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 41 6e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 40 0.002
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 39 0.002
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 39 0.002
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens] 39 0.002
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 39 0.003
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 39 0.003
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens] 39 0.003
gi|4504063 golgin 97 [Homo sapiens] 39 0.003
gi|55770834 centromere protein F [Homo sapiens] 39 0.003
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 39 0.004
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 39 0.004
gi|161702986 ezrin [Homo sapiens] 38 0.007
gi|21614499 ezrin [Homo sapiens] 38 0.007
>gi|156151377 suppressor of IKK epsilon isoform 2 [Homo sapiens]
Length = 207
Score = 398 bits (1022), Expect = e-111
Identities = 207/207 (100%), Positives = 207/207 (100%)
Query: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD 60
MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD
Sbjct: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD 60
Query: 61 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 120
MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK
Sbjct: 61 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 120
Query: 121 AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL 180
AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL
Sbjct: 121 AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL 180
Query: 181 RELLSISSESLQARKENSMDTASQAIK 207
RELLSISSESLQARKENSMDTASQAIK
Sbjct: 181 RELLSISSESLQARKENSMDTASQAIK 207
>gi|156151379 suppressor of IKK epsilon isoform 1 [Homo sapiens]
Length = 211
Score = 392 bits (1007), Expect = e-109
Identities = 207/211 (98%), Positives = 207/211 (98%), Gaps = 4/211 (1%)
Query: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQ----YQE 56
MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQ YQE
Sbjct: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQVRQRYQE 60
Query: 57 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 116
DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM
Sbjct: 61 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 120
Query: 117 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE 176
VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE
Sbjct: 121 VAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELE 180
Query: 177 NKELRELLSISSESLQARKENSMDTASQAIK 207
NKELRELLSISSESLQARKENSMDTASQAIK
Sbjct: 181 NKELRELLSISSESLQARKENSMDTASQAIK 211
>gi|24308111 FGFR1 oncogene partner 2 [Homo sapiens]
Length = 253
Score = 185 bits (469), Expect = 3e-47
Identities = 107/246 (43%), Positives = 151/246 (61%), Gaps = 51/246 (20%)
Query: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD 60
MSCTIEK L DAK L+ERLR+HD AAESL++Q+ AL++RV AM+ QYQE+ +
Sbjct: 1 MSCTIEKALADAKALVERLRDHDDAAESLIEQTTALNKRVEAMK--------QYQEEIQE 52
Query: 61 MKDMSKYKPHILL----SQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLM 116
+ ++++++P L QEN QIR+LQQEN+EL SLEEHQ ALELIMSKYR+QM +L+
Sbjct: 53 LNEVARHRPRSTLVMGIQQENRQIRELQQENKELRTSLEEHQSALELIMSKYREQMFRLL 112
Query: 117 VAKKAVDAEPVLKAHQSHSA--------------------------------------EI 138
+A K D ++K + HS E+
Sbjct: 113 MASKKDDPGIIMKLKEQHSKIDMVHRNKSEGFFLDASRHILEAPQHGLERRHLEANQNEL 172
Query: 139 ESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSES-LQARKEN 197
++ +D+I EM VMRKA+++D+ Q CK QE++ QLE ENK LRE+L I+ ES L RK++
Sbjct: 173 QAHVDQITEMAAVMRKAIEIDEQQGCKEQERIFQLEQENKGLREILQITRESFLNLRKDD 232
Query: 198 SMDTAS 203
+ ++ S
Sbjct: 233 ASESTS 238
>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
Length = 775
Score = 45.4 bits (106), Expect = 3e-05
Identities = 35/127 (27%), Positives = 63/127 (49%), Gaps = 6/127 (4%)
Query: 78 TQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLK----AHQS 133
++++ ++ E + L+E Q+ + S ++ Q+ Q M +K AE L+ +
Sbjct: 304 SELQAIRDEKNQPDPRLQELQEEAARLKSHFQAQLQQEM--RKTALAEDQLRQQSQVEEQ 361
Query: 134 HSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQA 193
A +E+QI + E+ KA Q D K++E++ QL+LENK L S S
Sbjct: 362 RVAALENQISEVSELLGTYEKAKQKDQLAIQKLKERILQLDLENKTLALAASSRSPLDSH 421
Query: 194 RKENSMD 200
+E+S+D
Sbjct: 422 GEESSLD 428
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/196 (20%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDAS-DMKD 63
++K +T+ K E++ + L ++ L + + + + L +E++ D ++
Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703
Query: 64 MSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAKKAV 122
+ + L + ++ LQ EN+EL E+ + LEL+ + ++K + L++ +
Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI 763
Query: 123 DAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL-R 181
+ + + K ++ + +I+ Q++ + E+ + +Q + ++ ++L QLE ENK L +
Sbjct: 764 ENQRLQKTLENSNKKIQ-QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ 822
Query: 182 ELLSISSESLQARKEN 197
E + + Q KEN
Sbjct: 823 ETSQLEKDKKQLEKEN 838
Score = 37.7 bits (86), Expect = 0.007
Identities = 39/183 (21%), Positives = 95/183 (51%), Gaps = 23/183 (12%)
Query: 26 AESLVDQSAALHRRVAAMRE-AGTALPDQYQEDASDMKDMSKYKPHILLSQENTQIRDLQ 84
++ L+ + A L + + +RE + + QE+ + +S + +S E +++D++
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE-ARVKDIE 586
Query: 85 QENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDR 144
+EN+ L S++E L I ++ K+ + KK ++ K + E+E+++
Sbjct: 587 KENKILHESIKETSSKLSKI--EFEKRQI-----KKELEH---YKEKGERAEELENELHH 636
Query: 145 ICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELENKELREL------LSISSESLQARK 195
+ + E+++K + ++ ++ ++++ ++LE EN++L++ L+ ESL+ K
Sbjct: 637 LEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLE--K 694
Query: 196 ENS 198
ENS
Sbjct: 695 ENS 697
Score = 31.6 bits (70), Expect = 0.50
Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 12/143 (8%)
Query: 73 LSQENTQIRDLQQENRELWISLEEHQ------DALELIMSKYRKQMLQLMVAKKAVDAEP 126
+ Q ++++DL+ EN+ L +LEE + + LE ++ QL KK ++ E
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Query: 127 VLKAHQSHSAEIESQIDRICEMGEVMR--KAVQVDDDQFCKIQEKLAQLELENKELRELL 184
Q+ + + + + ++G + + K + + + + +L +LE ENKEL +
Sbjct: 839 KRLRQQAEIKDTTLEENNV-KIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897
Query: 185 SISSESLQARKENSMDTASQAIK 207
+I ++L +E D S+ +K
Sbjct: 898 TIDIKTLVTLRE---DLVSEKLK 917
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/196 (20%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDAS-DMKD 63
++K +T+ K E++ + L ++ L + + + + L +E++ D ++
Sbjct: 644 LQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703
Query: 64 MSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRK-QMLQLMVAKKAV 122
+ + L + ++ LQ EN+EL E+ + LEL+ + ++K + L++ +
Sbjct: 704 LELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI 763
Query: 123 DAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL-R 181
+ + + K ++ + +I+ Q++ + E+ + +Q + ++ ++L QLE ENK L +
Sbjct: 764 ENQRLQKTLENSNKKIQ-QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQ 822
Query: 182 ELLSISSESLQARKEN 197
E + + Q KEN
Sbjct: 823 ETSQLEKDKKQLEKEN 838
Score = 37.7 bits (86), Expect = 0.007
Identities = 39/183 (21%), Positives = 95/183 (51%), Gaps = 23/183 (12%)
Query: 26 AESLVDQSAALHRRVAAMRE-AGTALPDQYQEDASDMKDMSKYKPHILLSQENTQIRDLQ 84
++ L+ + A L + + +RE + + QE+ + +S + +S E +++D++
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE-ARVKDIE 586
Query: 85 QENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDR 144
+EN+ L S++E L I ++ K+ + KK ++ K + E+E+++
Sbjct: 587 KENKILHESIKETSSKLSKI--EFEKRQI-----KKELEH---YKEKGERAEELENELHH 636
Query: 145 ICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELENKELREL------LSISSESLQARK 195
+ + E+++K + ++ ++ ++++ ++LE EN++L++ L+ ESL+ K
Sbjct: 637 LEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLE--K 694
Query: 196 ENS 198
ENS
Sbjct: 695 ENS 697
Score = 31.6 bits (70), Expect = 0.50
Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 12/143 (8%)
Query: 73 LSQENTQIRDLQQENRELWISLEEHQ------DALELIMSKYRKQMLQLMVAKKAVDAEP 126
+ Q ++++DL+ EN+ L +LEE + + LE ++ QL KK ++ E
Sbjct: 779 IQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Query: 127 VLKAHQSHSAEIESQIDRICEMGEVMR--KAVQVDDDQFCKIQEKLAQLELENKELRELL 184
Q+ + + + + ++G + + K + + + + +L +LE ENKEL +
Sbjct: 839 KRLRQQAEIKDTTLEENNV-KIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRA 897
Query: 185 SISSESLQARKENSMDTASQAIK 207
+I ++L +E D S+ +K
Sbjct: 898 TIDIKTLVTLRE---DLVSEKLK 917
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 43.1 bits (100), Expect = 2e-04
Identities = 49/197 (24%), Positives = 90/197 (45%), Gaps = 28/197 (14%)
Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQY----------Q 55
+K+L + K ++L E A E+ +S +L + MR A + DQ Q
Sbjct: 1454 DKVLAEWK---QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQ 1510
Query: 56 EDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQL 115
E+ SD+ + L E T+ + ++QE +L ++LEE + +LE SK + L+L
Sbjct: 1511 EEISDLTEQIAETGKNLQEAEKTK-KLVEQEKSDLQVALEEVEGSLEHEESKILRVQLEL 1569
Query: 116 MVAKKAVDAEPV--------LKAHQSHSAE-IESQID-RICEMGEVMRKAVQVDDDQFCK 165
K +D + + LK + +AE ++S +D I + +R +++ D
Sbjct: 1570 SQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGD---- 1625
Query: 166 IQEKLAQLELENKELRE 182
+ E QL N+++ E
Sbjct: 1626 LNEMEIQLGHSNRQMAE 1642
Score = 38.1 bits (87), Expect = 0.005
Identities = 41/214 (19%), Positives = 95/214 (44%), Gaps = 21/214 (9%)
Query: 4 TIEKILTDAKTLLERLREHDAAAESLV----DQSAALHRRVAAMREAGTALPDQYQEDAS 59
++++ + D + L ++ + A E+ V ++ AL ++ + + +L + +Q+
Sbjct: 953 SLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLD 1012
Query: 60 DM-----KDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALE--LIMSKYR--- 109
D+ K K + L Q+ + ++ ++L LE + LE L MS+
Sbjct: 1013 DLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMD 1072
Query: 110 ----KQMLQLMVAKKAVDAEPV---LKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQ 162
KQ ++ + KK + + + Q HS + + +I + E + + ++ +
Sbjct: 1073 LENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTL 1132
Query: 163 FCKIQEKLAQLELENKELRELLSISSESLQARKE 196
KI+++ + L E +E+ E L +S + A+ E
Sbjct: 1133 RAKIEKQRSDLARELEEISERLEEASGATSAQIE 1166
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 42.4 bits (98), Expect = 3e-04
Identities = 42/204 (20%), Positives = 91/204 (44%), Gaps = 17/204 (8%)
Query: 8 ILTDAKTLLERLREHDAAAESLVDQSAALHRR---VAAMREAGTALPDQYQEDASDMKDM 64
+L DA+ +L+ L+ + + L AA +A A+ + ++ + D+
Sbjct: 1664 LLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
Query: 65 SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAV-D 123
+K K + Q+ LQ+E E+ LEE Q+ + +M K++ + Q + D
Sbjct: 1724 AKAKTAL-----EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQIND 1778
Query: 124 AEPVLKAHQSHSAEIESQIDRICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELENKEL 180
+ L+ E++ ++ + E + +++ + Q KI+E +LE E ++
Sbjct: 1779 LQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQV 1838
Query: 181 RELLSISSESLQARKENSMDTASQ 204
+ L ESL +R + +M+ ++
Sbjct: 1839 KRL-----ESLASRLKENMEKLTE 1857
Score = 33.5 bits (75), Expect = 0.13
Identities = 37/190 (19%), Positives = 81/190 (42%), Gaps = 33/190 (17%)
Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMS 65
+ +L +A +L ++L E D + +L L D +++ D ++
Sbjct: 1489 DMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAE----------LQDISSQESKDEASLA 1538
Query: 66 KYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELI-MSKYRKQMLQLMVAKKAVDA 124
K K Q+RDL+ + ++ L+E ++++ +K R +M
Sbjct: 1539 KVKK---------QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM------------ 1577
Query: 125 EPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELL 184
+ + Q+HS E+ES+ + + E + +K ++ + Q + E ++ E +EL L
Sbjct: 1578 -EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1636
Query: 185 SISSESLQAR 194
+ S+ + R
Sbjct: 1637 ATLSDQVNRR 1646
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 42.4 bits (98), Expect = 3e-04
Identities = 42/204 (20%), Positives = 91/204 (44%), Gaps = 17/204 (8%)
Query: 8 ILTDAKTLLERLREHDAAAESLVDQSAALHRR---VAAMREAGTALPDQYQEDASDMKDM 64
+L DA+ +L+ L+ + + L AA +A A+ + ++ + D+
Sbjct: 1664 LLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
Query: 65 SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAV-D 123
+K K + Q+ LQ+E E+ LEE Q+ + +M K++ + Q + D
Sbjct: 1724 AKAKTAL-----EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQIND 1778
Query: 124 AEPVLKAHQSHSAEIESQIDRICEMGEVMRKAV---QVDDDQFCKIQEKLAQLELENKEL 180
+ L+ E++ ++ + E + +++ + Q KI+E +LE E ++
Sbjct: 1779 LQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQV 1838
Query: 181 RELLSISSESLQARKENSMDTASQ 204
+ L ESL +R + +M+ ++
Sbjct: 1839 KRL-----ESLASRLKENMEKLTE 1857
Score = 33.5 bits (75), Expect = 0.13
Identities = 37/190 (19%), Positives = 81/190 (42%), Gaps = 33/190 (17%)
Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMS 65
+ +L +A +L ++L E D + +L L D +++ D ++
Sbjct: 1489 DMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAE----------LQDISSQESKDEASLA 1538
Query: 66 KYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELI-MSKYRKQMLQLMVAKKAVDA 124
K K Q+RDL+ + ++ L+E ++++ +K R +M
Sbjct: 1539 KVKK---------QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM------------ 1577
Query: 125 EPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELL 184
+ + Q+HS E+ES+ + + E + +K ++ + Q + E ++ E +EL L
Sbjct: 1578 -EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1636
Query: 185 SISSESLQAR 194
+ S+ + R
Sbjct: 1637 ATLSDQVNRR 1646
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 42.0 bits (97), Expect = 4e-04
Identities = 47/206 (22%), Positives = 94/206 (45%), Gaps = 30/206 (14%)
Query: 5 IEKILTDAKTLLERLREHDAAAES----LVDQSAALHRRVAAMREAGTALPDQYQEDASD 60
++K + D + L ++ + A E+ L ++ A L +A + + AL + +Q+ D
Sbjct: 954 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1013
Query: 61 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 120
L E ++ L + I LE+ D LE + + +K + L AK+
Sbjct: 1014 ------------LQAEEDKVNTLTKAK----IKLEQQVDDLEGSLEQEKKIRMDLERAKR 1057
Query: 121 AVDAEPVLKAHQSHSAEIES---QIDRICEMGEVMRKAVQ--VDDDQF--CKIQEKLAQL 173
++ + LK Q + +IE+ Q+D + E +Q ++D+Q ++Q+K+ +L
Sbjct: 1058 KLEGD--LKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKEL 1115
Query: 174 ELENKELRELLSISSES-LQARKENS 198
+ +EL E + S +A K+ S
Sbjct: 1116 QARIEELEEEIEAERASRAKAEKQRS 1141
Score = 34.3 bits (77), Expect = 0.077
Identities = 46/227 (20%), Positives = 94/227 (41%), Gaps = 41/227 (18%)
Query: 2 SCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDM 61
S EK + + K E+ +E A E+ + L ++ + + L Q Q +A +
Sbjct: 846 SAETEKEMANMKEEFEKTKEELAKTEA---KRKELEEKMVTLMQEKNDLQLQVQAEADSL 902
Query: 62 KDM---------SKYKPHILLSQENTQIRDLQQENRELWIS----------LEEHQDALE 102
D +K + + + + D ++ N EL L++ D LE
Sbjct: 903 ADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 103 LIMSKYRKQM----------------LQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRIC 146
L ++K K+ L +AK + + + +AHQ +++++ D++
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1022
Query: 147 EMGEV-MRKAVQVDDDQFCKIQEKLAQLELE--NKELRELLSISSES 190
+ + ++ QVDD + QEK +++LE ++L L ++ ES
Sbjct: 1023 TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQES 1069
Score = 34.3 bits (77), Expect = 0.077
Identities = 40/186 (21%), Positives = 74/186 (39%), Gaps = 18/186 (9%)
Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDM 64
+E ++++L L + A E +DQ L R +++ + L +Q E + ++
Sbjct: 1471 LEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHEL 1530
Query: 65 SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDA 124
K K + ++QE EL +LEE + +LE K + L+L K VD
Sbjct: 1531 EKIK------------KQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1578
Query: 125 ------EPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENK 178
E + + ++H +ES + A+++ + E QL N+
Sbjct: 1579 KIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1638
Query: 179 ELRELL 184
E L
Sbjct: 1639 MAAEAL 1644
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 41.6 bits (96), Expect = 5e-04
Identities = 44/195 (22%), Positives = 91/195 (46%), Gaps = 19/195 (9%)
Query: 16 LERLREHDAAAESLVDQSAALHRRVAA--------MREAGTALPDQYQEDASDMKDMSKY 67
+++LRE E ++ L +V + MRE L QY+E + +
Sbjct: 203 MDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSA 262
Query: 68 KPHILLSQENTQIRDLQQENRELW---ISLEEHQD---ALELIMSKYRKQMLQLMVAKKA 121
+ LL + N+ ++ +++ N+++ ISLEE L+ ++ + K+ QL + +
Sbjct: 263 EKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQL--QL 320
Query: 122 VDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELR 181
++ E + + S + + ++ E +R+ ++ DD Q+K+ Q+ EN EL+
Sbjct: 321 LEHETEMSGELTDSD--KERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQ 378
Query: 182 ELLSISSESLQARKE 196
L +E+ QA+ E
Sbjct: 379 SRLDYLTET-QAKTE 392
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 41.6 bits (96), Expect = 5e-04
Identities = 49/229 (21%), Positives = 97/229 (42%), Gaps = 30/229 (13%)
Query: 6 EKILTDAKTLLERLRE-------HDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDA 58
E+ + D + L RL E + + +D++ H+ A++++ TA + Q D
Sbjct: 452 EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDL 511
Query: 59 SDM------KDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQ- 111
+ KD LL + I L++E +L+ ++ + ++ K
Sbjct: 512 EQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNH 571
Query: 112 MLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKA----------VQVDDD 161
LQ V + E + +SH E+ D++ E +R A V +
Sbjct: 572 TLQEQVTQLT---EKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNS 628
Query: 162 QFCKIQEKLAQLELENKELRELLSISSESLQARK---ENSMDTASQAIK 207
Q + +EK++QL+++ K ELL + + A++ +N +DTA A++
Sbjct: 629 QLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQ 677
Score = 40.4 bits (93), Expect = 0.001
Identities = 44/193 (22%), Positives = 92/193 (47%), Gaps = 16/193 (8%)
Query: 7 KILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSK 66
+I T L + E +A L L + +++ + + + Q+ + + D+ K
Sbjct: 833 RIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEK 892
Query: 67 YKPHILLSQENTQIRDLQQENRELWISLEEHQDA---LELIMSKYRKQMLQLMVAKKAVD 123
L Q Q+ + +E +EL SLE+ ++A L+L ++ ++Q++Q
Sbjct: 893 TCKE-LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQ--------- 942
Query: 124 AEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELREL 183
A+ LK ++ +++ I+ + + E +K ++ + KI L + ELENK L++
Sbjct: 943 AQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGEL-KI-AVLQKTELENK-LQQQ 999
Query: 184 LSISSESLQARKE 196
L+ +++ L A KE
Sbjct: 1000 LTQAAQELAAEKE 1012
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 41.2 bits (95), Expect = 6e-04
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 9/185 (4%)
Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDM 64
+E+ T + + + RE + + L + L +AA A E A ++ +
Sbjct: 1686 VEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1745
Query: 65 SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDA 124
+ K IL + R L+ +L LEE Q EL+ +YRK +LQ+ + A
Sbjct: 1746 NLSKAAILEEK-----RQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1800
Query: 125 EPVLKAH-QSHSAEIESQIDRI-CEMGEVMRKAVQVDDDQFCKIQEKLAQLE--LENKEL 180
E A +S ++E QI + +GE A ++ KLAQ E LE +
Sbjct: 1801 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1860
Query: 181 RELLS 185
+LS
Sbjct: 1861 ERILS 1865
Score = 33.5 bits (75), Expect = 0.13
Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 15/109 (13%)
Query: 79 QIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ----SH 134
Q+R +Q + +ELW +EE + + E I S+ R+ +L K ++AE VL+ + S
Sbjct: 1671 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL----KGLEAE-VLRLQEELAASD 1725
Query: 135 SAEIESQIDRICEMGEV----MRKAVQVDDDQFCKIQEKLAQLELENKE 179
A ++Q DR EV + KA +++ + +++ +L QLE E +E
Sbjct: 1726 RARRQAQQDRDEMADEVANGNLSKAAILEEKR--QLEGRLGQLEEELEE 1772
Score = 32.0 bits (71), Expect = 0.38
Identities = 41/205 (20%), Positives = 79/205 (38%), Gaps = 31/205 (15%)
Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMS 65
E+ +T +RL++H E+ ++ +++ + A +++ED ++D +
Sbjct: 960 EECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQN 1019
Query: 66 KYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAE 125
LS+E + D E EE +L + KY + D E
Sbjct: 1020 SK-----LSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATI---------ADME 1065
Query: 126 PVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLS 185
L+ + E+E R+ D + ++QE++ + + +ELR L
Sbjct: 1066 DRLRKEEKGRQELEKLKRRL--------------DGESSELQEQMVEQQQRAEELRAQLG 1111
Query: 186 ISSESLQ---ARKENSMDTASQAIK 207
E LQ AR E+ +Q +K
Sbjct: 1112 RKEEELQAALARAEDEGGARAQLLK 1136
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 41.2 bits (95), Expect = 6e-04
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 9/185 (4%)
Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDM 64
+E+ T + + + RE + + L + L +AA A E A ++ +
Sbjct: 1678 VEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1737
Query: 65 SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDA 124
+ K IL + R L+ +L LEE Q EL+ +YRK +LQ+ + A
Sbjct: 1738 NLSKAAILEEK-----RQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1792
Query: 125 EPVLKAH-QSHSAEIESQIDRI-CEMGEVMRKAVQVDDDQFCKIQEKLAQLE--LENKEL 180
E A +S ++E QI + +GE A ++ KLAQ E LE +
Sbjct: 1793 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1852
Query: 181 RELLS 185
+LS
Sbjct: 1853 ERILS 1857
Score = 33.5 bits (75), Expect = 0.13
Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 15/109 (13%)
Query: 79 QIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ----SH 134
Q+R +Q + +ELW +EE + + E I S+ R+ +L K ++AE VL+ + S
Sbjct: 1663 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL----KGLEAE-VLRLQEELAASD 1717
Query: 135 SAEIESQIDRICEMGEV----MRKAVQVDDDQFCKIQEKLAQLELENKE 179
A ++Q DR EV + KA +++ + +++ +L QLE E +E
Sbjct: 1718 RARRQAQQDRDEMADEVANGNLSKAAILEEKR--QLEGRLGQLEEELEE 1764
Score = 32.0 bits (71), Expect = 0.38
Identities = 41/205 (20%), Positives = 79/205 (38%), Gaps = 31/205 (15%)
Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMS 65
E+ +T +RL++H E+ ++ +++ + A +++ED ++D +
Sbjct: 952 EECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQN 1011
Query: 66 KYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAE 125
LS+E + D E EE +L + KY + D E
Sbjct: 1012 SK-----LSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATI---------ADME 1057
Query: 126 PVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLS 185
L+ + E+E R+ D + ++QE++ + + +ELR L
Sbjct: 1058 DRLRKEEKGRQELEKLKRRL--------------DGESSELQEQMVEQQQRAEELRAQLG 1103
Query: 186 ISSESLQ---ARKENSMDTASQAIK 207
E LQ AR E+ +Q +K
Sbjct: 1104 RKEEELQAALARAEDEGGARAQLLK 1128
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 41.2 bits (95), Expect = 6e-04
Identities = 47/185 (25%), Positives = 77/185 (41%), Gaps = 9/185 (4%)
Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDM 64
+E+ T + + + RE + + L + L +AA A E A ++ +
Sbjct: 1719 VEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANG 1778
Query: 65 SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDA 124
+ K IL + R L+ +L LEE Q EL+ +YRK +LQ+ + A
Sbjct: 1779 NLSKAAILEEK-----RQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1833
Query: 125 EPVLKAH-QSHSAEIESQIDRI-CEMGEVMRKAVQVDDDQFCKIQEKLAQLE--LENKEL 180
E A +S ++E QI + +GE A ++ KLAQ E LE +
Sbjct: 1834 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1893
Query: 181 RELLS 185
+LS
Sbjct: 1894 ERILS 1898
Score = 33.5 bits (75), Expect = 0.13
Identities = 33/109 (30%), Positives = 59/109 (54%), Gaps = 15/109 (13%)
Query: 79 QIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ----SH 134
Q+R +Q + +ELW +EE + + E I S+ R+ +L K ++AE VL+ + S
Sbjct: 1704 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL----KGLEAE-VLRLQEELAASD 1758
Query: 135 SAEIESQIDRICEMGEV----MRKAVQVDDDQFCKIQEKLAQLELENKE 179
A ++Q DR EV + KA +++ + +++ +L QLE E +E
Sbjct: 1759 RARRQAQQDRDEMADEVANGNLSKAAILEEKR--QLEGRLGQLEEELEE 1805
Score = 32.0 bits (71), Expect = 0.38
Identities = 41/205 (20%), Positives = 79/205 (38%), Gaps = 31/205 (15%)
Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMS 65
E+ +T +RL++H E+ ++ +++ + A +++ED ++D +
Sbjct: 993 EECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQN 1052
Query: 66 KYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAE 125
LS+E + D E EE +L + KY + D E
Sbjct: 1053 SK-----LSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATI---------ADME 1098
Query: 126 PVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLS 185
L+ + E+E R+ D + ++QE++ + + +ELR L
Sbjct: 1099 DRLRKEEKGRQELEKLKRRL--------------DGESSELQEQMVEQQQRAEELRAQLG 1144
Query: 186 ISSESLQ---ARKENSMDTASQAIK 207
E LQ AR E+ +Q +K
Sbjct: 1145 RKEEELQAALARAEDEGGARAQLLK 1169
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 41.2 bits (95), Expect = 6e-04
Identities = 45/206 (21%), Positives = 93/206 (45%), Gaps = 30/206 (14%)
Query: 5 IEKILTDAKTLLERLREHDAAAES----LVDQSAALHRRVAAMREAGTALPDQYQEDASD 60
++K + D + L ++ + A E+ L ++ A L +A + + AL + +Q+ D
Sbjct: 956 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1015
Query: 61 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 120
L E ++ L + I LE+ D LE + + +K + L AK+
Sbjct: 1016 ------------LQAEEDKVNTLTKAK----IKLEQQVDDLEGSLEQEKKLRMDLERAKR 1059
Query: 121 AVDAEPVLKAHQSHSAEIESQIDRICEM-----GEVMRKAVQVDDDQF--CKIQEKLAQL 173
++ + LK Q +IE++ ++ E E+ +++D+Q ++Q+K+ +L
Sbjct: 1060 KLEGD--LKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
Query: 174 ELENKELRELLSISSES-LQARKENS 198
+ +EL E + S +A K+ S
Sbjct: 1118 QARIEELEEEIEAERASRAKAEKQRS 1143
Score = 33.9 bits (76), Expect = 0.100
Identities = 41/186 (22%), Positives = 74/186 (39%), Gaps = 18/186 (9%)
Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDM 64
+E +A++L L + A E +DQ L R +++ + L +Q E + ++
Sbjct: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHEL 1532
Query: 65 SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDA 124
K K + ++QE EL +LEE + +LE K + L+L K VD
Sbjct: 1533 EKIK------------KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580
Query: 125 ------EPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENK 178
E + + ++H +ES + A+++ + E QL N+
Sbjct: 1581 KIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
Query: 179 ELRELL 184
E L
Sbjct: 1641 MAAEAL 1646
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 41.2 bits (95), Expect = 6e-04
Identities = 45/206 (21%), Positives = 93/206 (45%), Gaps = 30/206 (14%)
Query: 5 IEKILTDAKTLLERLREHDAAAES----LVDQSAALHRRVAAMREAGTALPDQYQEDASD 60
++K + D + L ++ + A E+ L ++ A L +A + + AL + +Q+ D
Sbjct: 956 LKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1015
Query: 61 MKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK 120
L E ++ L + I LE+ D LE + + +K + L AK+
Sbjct: 1016 ------------LQAEEDKVNTLTKAK----IKLEQQVDDLEGSLEQEKKLRMDLERAKR 1059
Query: 121 AVDAEPVLKAHQSHSAEIESQIDRICEM-----GEVMRKAVQVDDDQF--CKIQEKLAQL 173
++ + LK Q +IE++ ++ E E+ +++D+Q ++Q+K+ +L
Sbjct: 1060 KLEGD--LKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKEL 1117
Query: 174 ELENKELRELLSISSES-LQARKENS 198
+ +EL E + S +A K+ S
Sbjct: 1118 QARIEELEEEIEAERASRAKAEKQRS 1143
Score = 33.9 bits (76), Expect = 0.100
Identities = 41/186 (22%), Positives = 74/186 (39%), Gaps = 18/186 (9%)
Query: 5 IEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDM 64
+E +A++L L + A E +DQ L R +++ + L +Q E + ++
Sbjct: 1473 LEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHEL 1532
Query: 65 SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDA 124
K K + ++QE EL +LEE + +LE K + L+L K VD
Sbjct: 1533 EKIK------------KQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580
Query: 125 ------EPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENK 178
E + + ++H +ES + A+++ + E QL N+
Sbjct: 1581 KIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
Query: 179 ELRELL 184
E L
Sbjct: 1641 MAAEAL 1646
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 39.7 bits (91), Expect = 0.002
Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 27/159 (16%)
Query: 55 QEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQ 114
+E+ S +KD + L ++ + Q QQ+ + ++EH+ +++ + Q+ Q
Sbjct: 704 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSI---IKEHEVSIQRTEKALKDQINQ 760
Query: 115 LMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVD--------------- 159
L + K D LK HQ+H +E+ I R GE+ + + ++D
Sbjct: 761 LELLLKERDKH--LKEHQAHVENLEADIKR--SEGELQQASAKLDVFQSYQSATHEQTKA 816
Query: 160 -DDQFCKIQEKLAQLELENKELRELLSISSESLQARKEN 197
++Q ++Q+KL LE E R LL+ ++A+K++
Sbjct: 817 YEEQLAQLQQKLLDLETE----RILLTKQVAEVEAQKKD 851
Score = 39.3 bits (90), Expect = 0.002
Identities = 48/224 (21%), Positives = 91/224 (40%), Gaps = 39/224 (17%)
Query: 9 LTDAKTLLERL------------REHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQ- 55
L DAK L+E+L R+ E ++ A L R+ M G L +Q +
Sbjct: 348 LRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEK 407
Query: 56 ---------EDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMS 106
E A ++ L ++ + QI+ +++ + E ISL++ +S
Sbjct: 408 SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQE-------LS 460
Query: 107 KYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQI-----DRICEMGEVMRKAVQVDDD 161
+ +++++ +M + K H+ A E ++ R E E M+ A++
Sbjct: 461 RVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQS 520
Query: 162 QFCKI-QEKLAQLELENKELRELLSISSESLQARKENSMDTASQ 204
++ KI QEK Q L +E L + +++ EN + Q
Sbjct: 521 EYLKISQEKEQQESLALEE----LELQKKAILTESENKLRDLQQ 560
Score = 38.5 bits (88), Expect = 0.004
Identities = 40/175 (22%), Positives = 84/175 (48%), Gaps = 17/175 (9%)
Query: 13 KTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHIL 72
K L R RE + +++S + + +++ +E Q+++ ++++ K IL
Sbjct: 498 KKLQTREREFQEQMKVALEKSQSEYLKISQEKE---------QQESLALEELELQKKAIL 548
Query: 73 LSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMV---AKKAVDAEPVLK 129
EN ++RDLQQE + E + +LE + + + Q L V A+K + +
Sbjct: 549 TESEN-KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITV 607
Query: 130 AHQSHSAEIES---QIDRI-CEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKEL 180
+ H E+ES Q D + E +V+++ Q + ++ + E+ + L++KE+
Sbjct: 608 MVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEI 662
Score = 35.0 bits (79), Expect = 0.045
Identities = 36/182 (19%), Positives = 83/182 (45%), Gaps = 15/182 (8%)
Query: 17 ERLREHDAAAESLV-DQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHILLSQ 75
E+ H +S++ + ++ R A+++ L +E +K+ + ++
Sbjct: 727 EQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 786
Query: 76 ENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHS 135
+ ++ +LQQ + +L + + +Q A Y +Q+ QL ++ E +L Q
Sbjct: 787 KRSE-GELQQASAKLDV-FQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV-- 842
Query: 136 AEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARK 195
AE+E+Q +C E+ +QV Q+ + QLE +N E+ + + ++ +++
Sbjct: 843 AEVEAQKKDVCT--ELDAHKIQV--------QDLMQQLEKQNSEMEQKVKSLTQVYESKL 892
Query: 196 EN 197
E+
Sbjct: 893 ED 894
Score = 32.3 bits (72), Expect = 0.29
Identities = 42/200 (21%), Positives = 90/200 (45%), Gaps = 18/200 (9%)
Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDM-KDM 64
++IL + + ++ ++RE ++ Q +++A ++ L ++Y+ + K M
Sbjct: 903 KQILVEKENMILQMREGQKKEIEILTQ------KLSAKEDSIHILNEEYETKFKNQEKKM 956
Query: 65 SKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSK--YRKQMLQLMVAKKAV 122
K K QE + + L QE + + E ALEL + + +ML++ A A
Sbjct: 957 EKVKQKAKEMQETLKKKLLDQEAK---LKKELENTALELSQKEKQFNAKMLEMAQANSAG 1013
Query: 123 DAEPVLKAHQSHSAEIESQID----RICEMGEVMRKAVQVDDDQFCKIQE-KLAQLELEN 177
++ V + + +IES + + ++ + K + ++ +I E +L + E E
Sbjct: 1014 ISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEV 1073
Query: 178 KELRE-LLSISSESLQARKE 196
EL++ +L E + KE
Sbjct: 1074 AELKQKILLFGCEKEEMNKE 1093
Score = 30.0 bits (66), Expect = 1.4
Identities = 47/227 (20%), Positives = 93/227 (40%), Gaps = 36/227 (15%)
Query: 1 MSCTI-EKILTDAKTLLERLRE-HDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDA 58
++C I E+ + + + L R +E H E L + L A + G P + E+
Sbjct: 1847 LTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQ---ALQQMDGRNKPTELLEEN 1903
Query: 59 SDMKDMSKYKPHILLSQENTQIRDLQQE------------------NRELWISLEEHQDA 100
++ K S LLS Q DL+ + ++L + +EHQ
Sbjct: 1904 TEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQE 1963
Query: 101 LELIMSKYR-------KQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMR 153
LE++ +Y KQ + + K + +++ + A+ E +++ + E +
Sbjct: 1964 LEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIK--ETIN 2021
Query: 154 KAVQVDDDQFCKIQEK----LAQLELENKELRELLSISSESLQARKE 196
KA +V+ + QE+ L ++ ++ +L+ E L AR+E
Sbjct: 2022 KAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREE 2068
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 39.3 bits (90), Expect = 0.002
Identities = 46/188 (24%), Positives = 84/188 (44%), Gaps = 17/188 (9%)
Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMS 65
E+IL AK ++L+ +A L ++ AA R A R+A Q +++ +D S
Sbjct: 1662 EEILAQAKENEKKLKSMEAEMIQLQEELAAAER---AKRQA-----QQERDELADEIANS 1713
Query: 66 KYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAE 125
K + L ++ R L+ +L LEE Q ELI + +K LQ+ ++ E
Sbjct: 1714 SGKGALALEEK----RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLE 1769
Query: 126 PVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLS 185
++H + Q++R + E+ K +++ K + + LE + +L E L
Sbjct: 1770 ---RSHAQKNENARQQLER--QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLD 1824
Query: 186 ISSESLQA 193
++ QA
Sbjct: 1825 NETKERQA 1832
Score = 33.9 bits (76), Expect = 0.100
Identities = 43/204 (21%), Positives = 94/204 (46%), Gaps = 23/204 (11%)
Query: 11 DAKTLLERL-REHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDM----- 64
+ K LERL ++ E L+ + + V + ++ AL Q +E + ++++
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Query: 65 ----SKYKPHILLS------QENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQ 114
+K + + L + + Q RD Q E ++ + + + +E + RKQ
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVRE--MEAELEDERKQRSM 1607
Query: 115 LMVAKKAVDAE-PVLKAH-QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQ 172
+ A+K ++ + L+AH S + + I ++ ++ M+ ++ DD +E LAQ
Sbjct: 1608 AVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQ 1667
Query: 173 LELENKELRELLSISSESLQARKE 196
+ K+L+ S+ +E +Q ++E
Sbjct: 1668 AKENEKKLK---SMEAEMIQLQEE 1688
Score = 32.7 bits (73), Expect = 0.22
Identities = 36/207 (17%), Positives = 87/207 (42%), Gaps = 13/207 (6%)
Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMS 65
+K+ + + L E+L E ++A + L + ++ + E L DQ + A + K +
Sbjct: 939 KKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
Query: 66 KYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKK----- 120
+++ T + + +++++ L +H+ + + + R++ Q +K
Sbjct: 999 DR-----IAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 121 ---AVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELEN 177
+ D + Q+ AE++ Q+ + E + V+ + Q +K+ +LE +
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 178 KELRELLSISSESLQARKENSMDTASQ 204
EL+E L S ++ D +
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEE 1140
Score = 31.6 bits (70), Expect = 0.50
Identities = 39/188 (20%), Positives = 82/188 (43%), Gaps = 22/188 (11%)
Query: 15 LLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHILLS 74
L ++ E AA + +++A + + +RE + + + ++ S+ +K +
Sbjct: 1078 LAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEK----- 1132
Query: 75 QENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSH 134
Q RDL +E L LE+ D+ K+ ++ + KK ++ E ++H
Sbjct: 1133 ----QKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEA-----KTH 1183
Query: 135 SAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENK------ELRELLSISS 188
A+I+ + + E + A Q++ + K + A+ LEN+ E++ LL
Sbjct: 1184 EAQIQEMRQKHSQAVEEL--AEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKG 1241
Query: 189 ESLQARKE 196
+S RK+
Sbjct: 1242 DSEHKRKK 1249
Score = 28.1 bits (61), Expect = 5.5
Identities = 39/242 (16%), Positives = 91/242 (37%), Gaps = 51/242 (21%)
Query: 6 EKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMS 65
E LT+ +TL +L + + L +R TA + +E D++
Sbjct: 865 ENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEAR- 923
Query: 66 KYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAK---KAV 122
+ +E + + LQ E +++ +++E ++ LE S +K L+ + + K +
Sbjct: 924 -------VEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKL 976
Query: 123 DAEPVL----------------------------------------KAHQSHSAEIESQI 142
+ E ++ H++ ++E ++
Sbjct: 977 EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
Query: 143 DRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKENSMDTA 202
R + + + K + + + +++A+L+ + EL+ L+ E LQA + A
Sbjct: 1037 RREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA 1096
Query: 203 SQ 204
+Q
Sbjct: 1097 AQ 1098
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 39.3 bits (90), Expect = 0.002
Identities = 49/203 (24%), Positives = 87/203 (42%), Gaps = 36/203 (17%)
Query: 17 ERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHILLSQE 76
E L+ + ES+V Q L R ++E + L +Q +E ++ +M K K I
Sbjct: 1492 ELLKLKNTYEESIVGQET-LRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLI----- 1545
Query: 77 NTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAK---------KAVDAEPV 127
++E E+ ++LEE + ALE SK L+L+ AK K + E
Sbjct: 1546 -------EEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENF 1598
Query: 128 LKAHQSHSAEIESQIDRICEMG-EVMRKAVQVDDD-------------QFCKIQEKLAQL 173
+ Q ++S +D + EV R ++++D Q + + L QL
Sbjct: 1599 RRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQL 1658
Query: 174 ELENKELRELLSISSESLQARKE 196
+++ K+L+ L S++ KE
Sbjct: 1659 QIQIKDLQMQLDDSTQLNSDLKE 1681
Score = 28.5 bits (62), Expect = 4.2
Identities = 26/109 (23%), Positives = 44/109 (40%), Gaps = 12/109 (11%)
Query: 15 LLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHILLS 74
L R+RE + E + +SA R + L Q +ED + LS
Sbjct: 1827 LESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKN------------LS 1874
Query: 75 QENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVD 123
+ TQ+ LQ + + +E + +SKY+KQ +L K+ +
Sbjct: 1875 RMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAE 1923
>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
Length = 1012
Score = 39.3 bits (90), Expect = 0.002
Identities = 46/205 (22%), Positives = 86/205 (41%), Gaps = 40/205 (19%)
Query: 2 SCTIEKILTDAKTLL-----ERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQE 56
SC + I TLL ERL E +A E + + + + ++E
Sbjct: 807 SCLLSNIKGRKITLLTYEEIERLLEEEAVKEFIEPE-----------------IDESFKE 849
Query: 57 DASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALEL----IMSKYRKQM 112
D + K+ K + E ++E +I +E+ + L ++S +R+
Sbjct: 850 DEEESKEDRKLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRESA 909
Query: 113 LQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQ 172
Q +A+K ++A V++ Q E+E++ R+A + +D + EKL
Sbjct: 910 KQGTLAQKYLEAMAVIEHMQEKLLEVENRA----------RQAEEKFEDAY----EKLHH 955
Query: 173 LELENKELRELLSISSESLQARKEN 197
++NK+L EL+ S + + KEN
Sbjct: 956 TLIKNKDLEELVMTSRKESKEEKEN 980
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 38.9 bits (89), Expect = 0.003
Identities = 51/219 (23%), Positives = 96/219 (43%), Gaps = 39/219 (17%)
Query: 16 LERLREHDAAAESLVDQSAALHRRVAA--------MREAGTALPDQYQEDASDMKDMSKY 67
+++LRE E ++ L +V + MRE L QY+E + +
Sbjct: 203 MDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSA 262
Query: 68 KPHILLSQENTQIRDLQQENRELW---ISLEEHQ------DALELIMSKYRKQM-LQLMV 117
+ LL + N+ ++ +++ N+++ ISLEE D L M K R Q+ LQL+
Sbjct: 263 EKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLE 322
Query: 118 AKKAV----------------DAEPVLKAHQSHSAEI----ESQIDRICEMGEVMRKAVQ 157
+ + +A L+ H ++ + ++ ++ E E ++K +Q
Sbjct: 323 HETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKLQ 382
Query: 158 VDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKE 196
++ EK++ LE EN EL+ L +E+ QA+ E
Sbjct: 383 QKQLLILQLLEKISFLEGENNELQSRLDYLTET-QAKTE 420
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 38.9 bits (89), Expect = 0.003
Identities = 51/219 (23%), Positives = 96/219 (43%), Gaps = 39/219 (17%)
Query: 16 LERLREHDAAAESLVDQSAALHRRVAA--------MREAGTALPDQYQEDASDMKDMSKY 67
+++LRE E ++ L +V + MRE L QY+E + +
Sbjct: 203 MDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSA 262
Query: 68 KPHILLSQENTQIRDLQQENRELW---ISLEEHQ------DALELIMSKYRKQM-LQLMV 117
+ LL + N+ ++ +++ N+++ ISLEE D L M K R Q+ LQL+
Sbjct: 263 EKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLE 322
Query: 118 AKKAV----------------DAEPVLKAHQSHSAEI----ESQIDRICEMGEVMRKAVQ 157
+ + +A L+ H ++ + ++ ++ E E ++K +Q
Sbjct: 323 HETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKLQ 382
Query: 158 VDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKE 196
++ EK++ LE EN EL+ L +E+ QA+ E
Sbjct: 383 QKQLLILQLLEKISFLEGENNELQSRLDYLTET-QAKTE 420
>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
Length = 466
Score = 38.9 bits (89), Expect = 0.003
Identities = 51/219 (23%), Positives = 96/219 (43%), Gaps = 39/219 (17%)
Query: 16 LERLREHDAAAESLVDQSAALHRRVAA--------MREAGTALPDQYQEDASDMKDMSKY 67
+++LRE E ++ L +V + MRE L QY+E + +
Sbjct: 203 MDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSA 262
Query: 68 KPHILLSQENTQIRDLQQENRELW---ISLEEHQ------DALELIMSKYRKQM-LQLMV 117
+ LL + N+ ++ +++ N+++ ISLEE D L M K R Q+ LQL+
Sbjct: 263 EKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLE 322
Query: 118 AKKAV----------------DAEPVLKAHQSHSAEI----ESQIDRICEMGEVMRKAVQ 157
+ + +A L+ H ++ + ++ ++ E E ++K +Q
Sbjct: 323 HETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEIESLKKKLQ 382
Query: 158 VDDDQFCKIQEKLAQLELENKELRELLSISSESLQARKE 196
++ EK++ LE EN EL+ L +E+ QA+ E
Sbjct: 383 QKQLLILQLLEKISFLEGENNELQSRLDYLTET-QAKTE 420
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 38.9 bits (89), Expect = 0.003
Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 7/136 (5%)
Query: 73 LSQENTQIRDLQQENRELWISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQ 132
LS Q+R+LQ+ +L I+LE+HQD+ M K+++Q + A +A AE + A
Sbjct: 74 LSDYAEQVRNLQKIKEKLEIALEKHQDS---SMRKFQEQN-ETFQANRAKMAEGLALALA 129
Query: 133 SHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQL-ELENKELRELLSISSESL 191
E ++D++ + ++ +Q +Q + ++ ++ ELE + +EL I + +
Sbjct: 130 RKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKI--KHM 187
Query: 192 QARKENSMDTASQAIK 207
+KE S+ Q ++
Sbjct: 188 LLKKEESLGKMEQELE 203
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 38.9 bits (89), Expect = 0.003
Identities = 44/209 (21%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 4 TIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKD 63
T+ K T L E+++E ES QS LH A E + Q +SD+ +
Sbjct: 1969 TMSKKTTALDQLSEKMKEKTQELES--HQSECLHCIQVAEAEVKEKT-ELLQTLSSDVSE 2025
Query: 64 MSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDAL--------------ELIMSKYR 109
+ K K H+ +++ L+++++ L ++ E ++ + E + ++
Sbjct: 2026 LLKDKTHL-----QEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS 2080
Query: 110 KQMLQLMVAKKAVDAEPVLKAHQS-HSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQE 168
+ + + KA++A V K + + + ++ ++ E +R ++ D+ + I E
Sbjct: 2081 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAE 2140
Query: 169 KLAQLELENKELRELLSISSESLQARKEN 197
KL + E EN L++ + LQ +EN
Sbjct: 2141 KLKERERENDSLKDKVENLERELQMSEEN 2169
Score = 35.0 bits (79), Expect = 0.045
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 15/127 (11%)
Query: 73 LSQENTQIRDLQQENRELWISLEEHQ-DALELIMSKYRKQMLQLMVAKKAVDAEPVLKAH 131
+S++ T + L ++ +E LE HQ + L I Q+ + V +K +L+
Sbjct: 1970 MSKKTTALDQLSEKMKEKTQELESHQSECLHCI------QVAEAEVKEKT----ELLQTL 2019
Query: 132 QSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESL 191
S +E+ + E + + K Q C+++ ++AQL NKE +ELL SESL
Sbjct: 2020 SSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQL---NKE-KELLVKESESL 2075
Query: 192 QARKENS 198
QAR S
Sbjct: 2076 QARLSES 2082
Score = 33.9 bits (76), Expect = 0.100
Identities = 51/217 (23%), Positives = 92/217 (42%), Gaps = 32/217 (14%)
Query: 5 IEKILTDAKTLLERLR--------EHDAAAESLVDQSAALHRRVAA-------MREAGTA 49
++K+L+ K+LLE E A E L +Q L+ VAA M+ +
Sbjct: 2229 LDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQS 2288
Query: 50 LPDQYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENRELWISLEEHQDALELIMSKYR 109
L +E+ + K + L + E Q+ LQQ L+E + +L+ +
Sbjct: 2289 LDPPIEEEHQLRNSIEKLRAR-LEADEKKQLCVLQQ--------LKESEHHADLLKGRVE 2339
Query: 110 KQMLQLMVAKK-----AVDAEPVLKAHQSHSAEIE--SQIDRICEMGEV-MRKAVQVDDD 161
+L +A+ A++AE ++ A+IE +Q R E+ V +R + +
Sbjct: 2340 NLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTN 2399
Query: 162 QFCKIQEKLAQLELENKELRELLSISSESLQARKENS 198
+ K QE++++LE+ N +L + KE S
Sbjct: 2400 ELQKEQERISELEIINSSFENILQEKEQEKVQMKEKS 2436
Score = 33.9 bits (76), Expect = 0.100
Identities = 46/228 (20%), Positives = 101/228 (44%), Gaps = 35/228 (15%)
Query: 1 MSCTIEKILTDAKTLLERLREH-------DAAAESLVDQSAALHRRVAAMREAGTALPDQ 53
+S +E + + LL+ L E ++ L+ + +++ E + L +Q
Sbjct: 2471 LSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQ 2530
Query: 54 YQEDASDMKDMSKYK-PHILLSQENTQIR----DLQQENRELWISLEEHQDALELIMSKY 108
Q+ + +S+ + H L ++N ++R +L+Q+ + L QD LE++ S Y
Sbjct: 2531 IQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSY 2590
Query: 109 RKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD-------- 160
+ +L + K +D ++ +A+ E+++ R EM E+ +K ++ +
Sbjct: 2591 KNLENELELTK--MDKMSFVEKVNKMTAK-ETELQR--EMHEMAQKTAELQEELSGEKNR 2645
Query: 161 ---------DQFCKIQEKLAQLELENKELRELLSISSESLQARKENSM 199
++ +++L +L LEN EL++ L + Q KE +
Sbjct: 2646 LAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKD-QVEKEGKV 2692
Score = 30.0 bits (66), Expect = 1.4
Identities = 42/163 (25%), Positives = 69/163 (42%), Gaps = 25/163 (15%)
Query: 31 DQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHILLSQENTQIRDLQQENREL 90
DQ A+H A + ++P + E + S +N+ I LQ L
Sbjct: 788 DQQPAMHHSFANIIGEQGSMPSERSECRLEADQ----------SPKNSAI--LQNRVDSL 835
Query: 91 WISLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGE 150
SLE + + S +KQ +L+ K ++ E ++KA Q H + + RI ++ E
Sbjct: 836 EFSLESQKQ----MNSDLQKQCEELVQIKGEIE-ENLMKAEQMHQSFVAETSQRISKLQE 890
Query: 151 VMRKAVQVDDDQFCKIQEKLAQLELENKELRELLSISSESLQA 193
V + E L+ LE + KEL +LL+ E+ QA
Sbjct: 891 DTSAHQNV-------VAETLSALENKEKEL-QLLNDKVETEQA 925
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 38.5 bits (88), Expect = 0.004
Identities = 44/207 (21%), Positives = 92/207 (44%), Gaps = 29/207 (14%)
Query: 15 LLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHILLS 74
LL+ L + ++L D +R+ A +R + L +Y + K SK +
Sbjct: 787 LLQELENKEKKLKNLEDSLEDYNRKFAVIRHQQSLLYKEYLSEKETWKTESK-----TIK 841
Query: 75 QENTQIRDLQQEN-------RELWISLEEHQDALELIMSKYRKQMLQLMVAKKA------ 121
+E ++ D Q++ L +L+ D ++ I+++ +++ L V +K+
Sbjct: 842 EEKRKLEDQVQQDAIKVKEYNNLLNALQMDSDEMKKILAENSRKITVLQVNEKSLIRQYT 901
Query: 122 --VDAEPVL-KAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQE------KLAQ 172
V+ E L K ++ E+ S +CE +++ ++ + +Q+ L++
Sbjct: 902 TLVELERQLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIAALQKVVDNSVSLSE 961
Query: 173 LELENKELRELLSISSESLQARKENSM 199
LEL NK+ EL + + LQ K+N +
Sbjct: 962 LELANKQYNELTAKYRDILQ--KDNML 986
Score = 32.7 bits (73), Expect = 0.22
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 13/174 (7%)
Query: 19 LREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKP--HILLSQE 76
+R H A V + L R ++E AL Q+ +D +S + H QE
Sbjct: 2003 MRAHQALPRDSVVEDLHLQNRY--LQEKLHALEKQFSKDTYSKPSISGIESDDHCQREQE 2060
Query: 77 -NTQIRDLQQENRELWISLEEHQDALELIMSKYR--KQMLQLMVAKKAVDAEPVLKAHQS 133
+ L EN EL LE+ L + ++ R K+M + + +KA + S
Sbjct: 2061 LQKENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVQRKLGHVRGS 2120
Query: 134 -HSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQ-----EKLAQLELENKELR 181
S + ++++ + + + + VQ +++Q K EK+A +E EN++L+
Sbjct: 2121 GRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANIEQENEKLK 2174
Score = 28.1 bits (61), Expect = 5.5
Identities = 43/210 (20%), Positives = 87/210 (41%), Gaps = 26/210 (12%)
Query: 5 IEKILTDAKTLLERLRE-HDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKD 63
+EK + K + +LRE D A + +A R + L D YQ + +
Sbjct: 1141 LEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDKEVESLRMQLLD-YQAQSDEKSL 1199
Query: 64 MSKYKPHIL------------LSQENTQIRDLQQENRELWISLEEHQDALELIM------ 105
++K H + L ++++ ++ N L L+E + AL
Sbjct: 1200 IAKLHQHNVSLQLSEATALGKLESITSKLQKMEAYNLRLEQKLDEKEQALYYARLEGRNR 1259
Query: 106 SKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCK 165
+K+ +Q +Q + ++ A P+ + + I+ Q D++ M E+ +
Sbjct: 1260 AKHLRQTIQSL-RRQFSGALPLAQQEKFSKTMIQLQNDKLKIMQEMKNS-----QQEHRN 1313
Query: 166 IQEKLAQLELENKELRELLSISSESLQARK 195
++ K ++EL+ K L EL+S ++ A+K
Sbjct: 1314 MENKTLEMELKLKGLEELISTLKDTKGAQK 1343
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
1 [Homo sapiens]
Length = 1412
Score = 38.5 bits (88), Expect = 0.004
Identities = 54/229 (23%), Positives = 101/229 (44%), Gaps = 35/229 (15%)
Query: 1 MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRV-AAMREAGTA-------LPD 52
M ++KIL DAK L L + E L Q+ + R +AM ++G L +
Sbjct: 1188 MENNVQKILLDAKPDLPTL----SRIEILAPQNGLCNARFGSAMEKSGKMDVAEALELSE 1243
Query: 53 QYQEDAS-------DMKDMSKYKPHILLS-QENTQIRDLQQENRELWIS----LEEHQDA 100
+ D S ++K+MS + LS QE ++ L+Q + +L L+
Sbjct: 1244 KLYLDMSKTLGSLMNIKNMSGHVSMKYLSRQEREKVNQLRQRDLDLVFDKITQLKNQLGR 1303
Query: 101 LELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDD 160
E ++ Y K + QL +K +++ +QS A++E I + E ++++A++ +
Sbjct: 1304 KEELLRGYEKDVEQLRRSKVSIEM------YQSQVAKLEDDIYKEAEEKALLKEALERME 1357
Query: 161 DQFCKIQEKLAQLELENKEL---RELLSISSESLQARKENSMDTASQAI 206
Q C QEK + +++ + L + E RKE S ++ +
Sbjct: 1358 HQLC--QEKRINRAIRQQKVGTRKASLKMDQEREMLRKETSSKSSQSLL 1404
Score = 27.3 bits (59), Expect = 9.4
Identities = 33/170 (19%), Positives = 75/170 (44%), Gaps = 23/170 (13%)
Query: 59 SDMKDMSKYKPHILLSQENTQIRDLQQENRELWIS-------------LEEHQDALELIM 105
SD + SKYK I+ + +N ++ +L Q+ E S L+E DA + +
Sbjct: 241 SDYEIESKYKDVIIANLQN-EVAELSQKVSETTTSRQNEKEISQKCQVLDEDIDAKQKEI 299
Query: 106 SKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICE-------MGEVMRKAVQV 158
+ Q+ L V + L S ++++ + + M ++K +
Sbjct: 300 QSLKSQISALQKGYSKVLCQ-TLSERNSEITSLKNEGENLKRDNAITSGMVSSLQKDILA 358
Query: 159 DDDQFCKIQEKLAQLELENKEL-RELLSISSESLQARKENSMDTASQAIK 207
D+Q +++E+++ L+ +NK+ +L ++ S ++E + A + ++
Sbjct: 359 KDEQVQQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEELKQEDAHRELR 408
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 37.7 bits (86), Expect = 0.007
Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 39/194 (20%)
Query: 17 ERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHILLSQE 76
ER R + A D+ AAL + R+A + Q Q A ++++Y I L +E
Sbjct: 378 ERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAA----ELAEYTAKIALLEE 433
Query: 77 -----NTQIRDLQQENRELWISLEEHQDALELIMSK--------YRKQMLQLMVAKKAVD 123
++ + Q +E L + ++ L L+M+ Y + + +
Sbjct: 434 ARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEG 493
Query: 124 AEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELREL 183
AEP +SAE+ S+ + DD+ ++++ + E + R+L
Sbjct: 494 AEPT-----GYSAELSSE---------------GIRDDR--NEEKRITEAEKNERVQRQL 531
Query: 184 LSISSESLQARKEN 197
L++SSE QAR EN
Sbjct: 532 LTLSSELSQARDEN 545
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 37.7 bits (86), Expect = 0.007
Identities = 45/194 (23%), Positives = 81/194 (41%), Gaps = 39/194 (20%)
Query: 17 ERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASDMKDMSKYKPHILLSQE 76
ER R + A D+ AAL + R+A + Q Q A ++++Y I L +E
Sbjct: 378 ERKRAQEEAERLEADRMAALRAKEELERQAVDQIKSQEQLAA----ELAEYTAKIALLEE 433
Query: 77 -----NTQIRDLQQENRELWISLEEHQDALELIMSK--------YRKQMLQLMVAKKAVD 123
++ + Q +E L + ++ L L+M+ Y + + +
Sbjct: 434 ARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVSYHVQESLQDEG 493
Query: 124 AEPVLKAHQSHSAEIESQIDRICEMGEVMRKAVQVDDDQFCKIQEKLAQLELENKELREL 183
AEP +SAE+ S+ + DD+ ++++ + E + R+L
Sbjct: 494 AEPT-----GYSAELSSE---------------GIRDDR--NEEKRITEAEKNERVQRQL 531
Query: 184 LSISSESLQARKEN 197
L++SSE QAR EN
Sbjct: 532 LTLSSELSQARDEN 545
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.125 0.326
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,185,277
Number of Sequences: 37866
Number of extensions: 229032
Number of successful extensions: 1965
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 298
Number of HSP's that attempted gapping in prelim test: 1444
Number of HSP's gapped (non-prelim): 749
length of query: 207
length of database: 18,247,518
effective HSP length: 98
effective length of query: 109
effective length of database: 14,536,650
effective search space: 1584494850
effective search space used: 1584494850
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.