Search of human proteins with 15451931

Search of human proteins with 15451931

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]
         (623 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]                 1272   0.0  
gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]                 1190   0.0  
gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]                  789   0.0  
gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]                 555   e-158
gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]                  550   e-156
gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]                   543   e-154
gi|56786144 dual specificity phosphatase 23 [Homo sapiens]             59   1e-08
gi|30089952 protein tyrosine phosphatase domain containing 1 pro...    57   5e-08
gi|30089950 protein tyrosine phosphatase domain containing 1 pro...    57   5e-08
gi|14589856 protein tyrosine phosphatase type IVA, member 3 isof...    55   2e-07
gi|4506283 protein tyrosine phosphatase type IVA, member 1 [Homo...    53   7e-07
gi|18104971 protein tyrosine phosphatase type IVA, member 2 isof...    51   4e-06
gi|169162376 PREDICTED: similar to protein tyrosine phosphatase ...    45   2e-04
gi|14589854 protein tyrosine phosphatase type IVA, member 3 isof...    45   2e-04
gi|38372911 dual specificity phosphatase 16 [Homo sapiens]             44   4e-04
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  44   4e-04
gi|51093845 dual specificity phosphatase 18 [Homo sapiens]             43   0.001
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi...    43   0.001
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi...    43   0.001
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    43   0.001
gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo sap...    42   0.001
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi...    42   0.001
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ...    42   0.002
gi|194733759 serine/threonine/tyrosine interacting protein [Homo...    42   0.002
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ...    42   0.002
gi|73765544 phosphatase and tensin homolog [Homo sapiens]              42   0.002
gi|5902002 dual specificity phosphatase 14 [Homo sapiens]              40   0.008
gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sap...    39   0.014
gi|4758204 dual specificity phosphatase 1 [Homo sapiens]               39   0.014
gi|108802609 protein tyrosine phosphatase, non-receptor type 20 ...    39   0.014

>gi|15451931 CDC14 homolog A isoform 2 [Homo sapiens]
          Length = 623

 Score = 1272 bits (3291), Expect = 0.0
 Identities = 623/623 (100%), Positives = 623/623 (100%)

Query: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60
           MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV
Sbjct: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60

Query: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120
           YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS
Sbjct: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120

Query: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180
           GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF
Sbjct: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180

Query: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240
           NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA
Sbjct: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240

Query: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300
           GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT
Sbjct: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300

Query: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360
           HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD
Sbjct: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360

Query: 361 DMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDD 420
           DMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDD
Sbjct: 361 DMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDD 420

Query: 421 TKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSR 480
           TKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSR
Sbjct: 421 TKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSR 480

Query: 481 LASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSS 540
           LASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSS
Sbjct: 481 LASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSS 540

Query: 541 NSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIPVSAQTPPPGPQNPEC 600
           NSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIPVSAQTPPPGPQNPEC
Sbjct: 541 NSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIPVSAQTPPPGPQNPEC 600

Query: 601 NFCALPSQPRLPPKKFNSAKEAF 623
           NFCALPSQPRLPPKKFNSAKEAF
Sbjct: 601 NFCALPSQPRLPPKKFNSAKEAF 623


>gi|15451929 CDC14 homolog A isoform 1 [Homo sapiens]
          Length = 594

 Score = 1190 bits (3078), Expect = 0.0
 Identities = 585/585 (100%), Positives = 585/585 (100%)

Query: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60
           MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV
Sbjct: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60

Query: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120
           YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS
Sbjct: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120

Query: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180
           GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF
Sbjct: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180

Query: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240
           NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA
Sbjct: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240

Query: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300
           GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT
Sbjct: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300

Query: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360
           HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD
Sbjct: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360

Query: 361 DMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDD 420
           DMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDD
Sbjct: 361 DMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDD 420

Query: 421 TKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSR 480
           TKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSR
Sbjct: 421 TKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSR 480

Query: 481 LASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSS 540
           LASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSS
Sbjct: 481 LASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSS 540

Query: 541 NSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIP 585
           NSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIP
Sbjct: 541 NSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIP 585


>gi|15451933 CDC14 homolog A isoform 3 [Homo sapiens]
          Length = 383

 Score =  789 bits (2037), Expect = 0.0
 Identities = 379/379 (100%), Positives = 379/379 (100%)

Query: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60
           MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV
Sbjct: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60

Query: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120
           YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS
Sbjct: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120

Query: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180
           GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF
Sbjct: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180

Query: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240
           NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA
Sbjct: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240

Query: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300
           GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT
Sbjct: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300

Query: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360
           HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD
Sbjct: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLD 360

Query: 361 DMSIGGNLSKTQNMERFGE 379
           DMSIGGNLSKTQNMERFGE
Sbjct: 361 DMSIGGNLSKTQNMERFGE 379


>gi|116008458 CDC14 homolog B isoform 3 [Homo sapiens]
          Length = 461

 Score =  555 bits (1430), Expect = e-158
 Identities = 271/480 (56%), Positives = 349/480 (72%), Gaps = 28/480 (5%)

Query: 1   MAAESGELIGACEFMKDRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMV 60
           M+ E        E +KDRL FA L +RPKS  N HYFSID EL YENFYADFGPLNLAMV
Sbjct: 1   MSREGAGAALVAEVIKDRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMV 60

Query: 61  YRYCCKLNKKLKSYSLSRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLS 120
           YRYCCK+NKKLKS ++ RKKIVH+T  DQRK+ANAAFL+G Y VIYL +TPEEAYR L+ 
Sbjct: 61  YRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIF 120

Query: 121 GSNPPYLPFRDASFGNCTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDF 180
           G    Y+PFRDA++G+C + +T+LDC   ++K +Q+GF +F +F++DEYEHYE+ ENGD 
Sbjct: 121 GETS-YIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDL 179

Query: 181 NWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDA 240
           NWI+P +F+AF GPH ++++E+GY  H+PE Y  YFK HNVT ++RLNK++Y+AKRFTDA
Sbjct: 180 NWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDA 239

Query: 241 GFEHYDLFFIDGSTPSDNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFT 300
           GF+H+DLFF DGSTP+D IV+ FL+ICEN EGAIAVHCKAGLGRTGTLIACY+MKHYR T
Sbjct: 240 GFDHHDLFFADGSTPTDAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMT 299

Query: 301 HAEIIAWIRICRPGSIIGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSE--GSINKILSG 358
            AE IAW+RICRPGS+IGPQQ FL  KQ +LW++GD FR KLK + + +   + +K+LSG
Sbjct: 300 AAETIAWVRICRPGSVIGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSG 359

Query: 359 LDDMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRS 418
           +DD+SI G     +N ++   +   DDD    NG+TQGD+LRALKS+RQ +T+       
Sbjct: 360 VDDISING----VENQDQQEPEPYSDDD--EINGVTQGDRLRALKSRRQSKTN------- 406

Query: 419 DDTKGHPRAVSQPFRLSSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSIN 478
                          L+  LQ S  + KTS+  +S SA   +    S S  ++V+S SI+
Sbjct: 407 ------------AIPLTVILQSSVQSCKTSEPNISGSAGITKRTTRSASRKSSVKSLSIS 454


>gi|15451936 CDC14 homolog B isoform 2 [Homo sapiens]
          Length = 498

 Score =  550 bits (1418), Expect = e-156
 Identities = 267/464 (57%), Positives = 343/464 (73%), Gaps = 28/464 (6%)

Query: 17  DRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKSYSL 76
           DRL FA L +RPKS  N HYFSID EL YENFYADFGPLNLAMVYRYCCK+NKKLKS ++
Sbjct: 54  DRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITM 113

Query: 77  SRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLSGSNPPYLPFRDASFGN 136
            RKKIVH+T  DQRK+ANAAFL+G Y VIYL +TPEEAYR L+ G    Y+PFRDA++G+
Sbjct: 114 LRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETS-YIPFRDAAYGS 172

Query: 137 CTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDFNWIVPGKFLAFSGPHP 196
           C + +T+LDC   ++K +Q+GF +F +F++DEYEHYE+ ENGD NWI+P +F+AF GPH 
Sbjct: 173 CNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHS 232

Query: 197 KSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPS 256
           ++++E+GY  H+PE Y  YFK HNVT ++RLNK++Y+AKRFTDAGF+H+DLFF DGSTP+
Sbjct: 233 RARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPT 292

Query: 257 DNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSI 316
           D IV+ FL+ICEN EGAIAVHCKAGLGRTGTLIACY+MKHYR T AE IAW+RICRPGS+
Sbjct: 293 DAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSV 352

Query: 317 IGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSE--GSINKILSGLDDMSIGGNLSKTQNM 374
           IGPQQ FL  KQ +LW++GD FR KLK + + +   + +K+LSG+DD+SI G     +N 
Sbjct: 353 IGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISING----VENQ 408

Query: 375 ERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDDTKGHPRAVSQPFRL 434
           ++   +   DDD    NG+TQGD+LRALKS+RQ +T+                      L
Sbjct: 409 DQQEPEPYSDDD--EINGVTQGDRLRALKSRRQSKTN-------------------AIPL 447

Query: 435 SSSLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSIN 478
           +  LQ S  + KTS+  +S SA   +    S S  ++V+S SI+
Sbjct: 448 TVILQSSVQSCKTSEPNISGSAGITKRTTRSASRKSSVKSLSIS 491


>gi|4502699 CDC14 homolog B isoform 1 [Homo sapiens]
          Length = 459

 Score =  543 bits (1398), Expect = e-154
 Identities = 251/397 (63%), Positives = 318/397 (80%), Gaps = 9/397 (2%)

Query: 17  DRLYFATLRNRPKSTVNTHYFSIDEELVYENFYADFGPLNLAMVYRYCCKLNKKLKSYSL 76
           DRL FA L +RPKS  N HYFSID EL YENFYADFGPLNLAMVYRYCCK+NKKLKS ++
Sbjct: 54  DRLCFAILYSRPKSASNVHYFSIDNELEYENFYADFGPLNLAMVYRYCCKINKKLKSITM 113

Query: 77  SRKKIVHYTCFDQRKRANAAFLIGAYAVIYLKKTPEEAYRALLSGSNPPYLPFRDASFGN 136
            RKKIVH+T  DQRK+ANAAFL+G Y VIYL +TPEEAYR L+ G    Y+PFRDA++G+
Sbjct: 114 LRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEEAYRILIFGETS-YIPFRDAAYGS 172

Query: 137 CTYNLTILDCLQGIRKGLQHGFFDFETFDVDEYEHYERVENGDFNWIVPGKFLAFSGPHP 196
           C + +T+LDC   ++K +Q+GF +F +F++DEYEHYE+ ENGD NWI+P +F+AF GPH 
Sbjct: 173 CNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHS 232

Query: 197 KSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPS 256
           ++++E+GY  H+PE Y  YFK HNVT ++RLNK++Y+AKRFTDAGF+H+DLFF DGSTP+
Sbjct: 233 RARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPT 292

Query: 257 DNIVRRFLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSI 316
           D IV+ FL+ICEN EGAIAVHCKAGLGRTGTLIACY+MKHYR T AE IAW+RICRPGS+
Sbjct: 293 DAIVKEFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSV 352

Query: 317 IGPQQHFLEEKQASLWVQGDIFRSKLKNRPSSE--GSINKILSGLDDMSIGGNLSKTQNM 374
           IGPQQ FL  KQ +LW++GD FR KLK + + +   + +K+LSG+DD+SI G     +N 
Sbjct: 353 IGPQQQFLVMKQTNLWLEGDYFRQKLKGQENGQHRAAFSKLLSGVDDISING----VENQ 408

Query: 375 ERFGEDNLEDDDVEMKNGITQGDKLRALKSQRQPRTS 411
           ++   +   DDD    NG+TQGD+LRALKS+RQ +T+
Sbjct: 409 DQQEPEPYSDDD--EINGVTQGDRLRALKSRRQSKTN 443


>gi|56786144 dual specificity phosphatase 23 [Homo sapiens]
          Length = 150

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 44/147 (29%), Positives = 70/147 (47%), Gaps = 21/147 (14%)

Query: 175 VENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAVVRLNKKIYEA 234
           V+  +F+W++PG+               G  L    A++ +     V  +V L ++    
Sbjct: 3   VQPPNFSWVLPGRLA-------------GLALPRLPAHYQFLLDLGVRHLVSLTER---G 46

Query: 235 KRFTDA--GFEHYDLFFIDGSTPSDNIVRRFLNICE--NTEG-AIAVHCKAGLGRTGTLI 289
              +D+  G   + L   D   P+ + + RF+ I +  N  G A+ VHC  G GRTGT++
Sbjct: 47  PPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTML 106

Query: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
           ACY++K       + IA IR  RPGSI
Sbjct: 107 ACYLVKERGLAAGDAIAEIRRLRPGSI 133


>gi|30089952 protein tyrosine phosphatase domain containing 1
           protein isoform 1 [Homo sapiens]
          Length = 806

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 232 YEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENT--EGAIAVHCKAGLGRTGTLI 289
           Y  + F +AG   Y+  + D    S   +   + +      EG +A+HC AGLGRTG LI
Sbjct: 194 YLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLI 253

Query: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
           ACY++   R T  + I ++R  RP SI
Sbjct: 254 ACYLVFATRMTADQAIIFVRAKRPNSI 280


>gi|30089950 protein tyrosine phosphatase domain containing 1
           protein isoform 2 [Homo sapiens]
          Length = 754

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 232 YEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNICENT--EGAIAVHCKAGLGRTGTLI 289
           Y  + F +AG   Y+  + D    S   +   + +      EG +A+HC AGLGRTG LI
Sbjct: 142 YLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFALQEGKVAIHCHAGLGRTGVLI 201

Query: 290 ACYVMKHYRFTHAEIIAWIRICRPGSI 316
           ACY++   R T  + I ++R  RP SI
Sbjct: 202 ACYLVFATRMTADQAIIFVRAKRPNSI 228


>gi|14589856 protein tyrosine phosphatase type IVA, member 3 isoform
           1 [Homo sapiens]
          Length = 173

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 6/115 (5%)

Query: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNI-----CENTE 271
           KK+  T VVR+ +  Y+       G    D  F DG+ P   +V  +L++     CE   
Sbjct: 38  KKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97

Query: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
             +AVHC AGLGR   L+A  +++     + + I +IR  R G+I   Q  +LE+
Sbjct: 98  SCVAVHCVAGLGRAPVLVALALIES-GMKYEDAIQFIRQKRRGAINSKQLTYLEK 151


>gi|4506283 protein tyrosine phosphatase type IVA, member 1 [Homo
           sapiens]
          Length = 173

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 37/115 (32%), Positives = 58/115 (50%), Gaps = 6/115 (5%)

Query: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNIC-----ENTE 271
           KK+ VT +VR+ +  Y+       G    D  F DG+ PS+ IV  +L++      E   
Sbjct: 38  KKYGVTTIVRVCEATYDTTLVEKEGIHVLDWPFDDGAPPSNQIVDDWLSLVKIKFREEPG 97

Query: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
             IAVHC AGLGR   L+A  +++     + + + +IR  R G+    Q  +LE+
Sbjct: 98  CCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNSKQLLYLEK 151


>gi|18104971 protein tyrosine phosphatase type IVA, member 2 isoform
           1 [Homo sapiens]
          Length = 167

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 36/115 (31%), Positives = 56/115 (48%), Gaps = 6/115 (5%)

Query: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNIC-----ENTE 271
           KK+ VT +VR+    Y+       G    D  F DG+ P + IV  +LN+      E   
Sbjct: 35  KKYGVTTLVRVCDATYDKAPVEKEGIHVLDWPFDDGAPPPNQIVDDWLNLLKTKFREEPG 94

Query: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
             +AVHC AGLGR   L+A  +++     + + + +IR  R G+    Q  +LE+
Sbjct: 95  CCVAVHCVAGLGRAPVLVALALIE-CGMKYEDAVQFIRQKRRGAFNSKQLLYLEK 148


>gi|169162376 PREDICTED: similar to protein tyrosine phosphatase 4a1
           isoform 1 [Homo sapiens]
          Length = 170

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 6/115 (5%)

Query: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLN-----ICENTE 271
           KK+  T +VR+ +  Y+       G    +  F DG+ PS+ IV  +L+      CE   
Sbjct: 35  KKYGATTIVRVCEATYDTTLVEKEGIHVLNWPFGDGAPPSNQIVADWLHFVKIKFCEEPG 94

Query: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
             IAV+C  GLG+   L+A   ++     H + + +I   R G+    Q  +LE+
Sbjct: 95  CYIAVNCIVGLGKAPVLVALASVEG-GMKHEDAVQFIGQKRSGAFKSKQLLYLEK 148


>gi|14589854 protein tyrosine phosphatase type IVA, member 3 isoform
           2 [Homo sapiens]
          Length = 148

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 5/73 (6%)

Query: 217 KKHNVTAVVRLNKKIYEAKRFTDAGFEHYDLFFIDGSTPSDNIVRRFLNI-----CENTE 271
           KK+  T VVR+ +  Y+       G    D  F DG+ P   +V  +L++     CE   
Sbjct: 38  KKYGATTVVRVCEVTYDKTPLEKDGITVVDWPFDDGAPPPGKVVEDWLSLVKAKFCEAPG 97

Query: 272 GAIAVHCKAGLGR 284
             +AVHC AGLGR
Sbjct: 98  SCVAVHCVAGLGR 110


>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
          Length = 665

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 54/247 (21%), Positives = 102/247 (41%), Gaps = 46/247 (18%)

Query: 263 FLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           F+   + + G + VHC AG+ R+ T+   Y+MK    +  E   +++  RP   I P  +
Sbjct: 229 FIEKAKASNGCVLVHCLAGISRSATIAIAYIMKRMDMSLDEAYRFVKEKRP--TISPNFN 286

Query: 323 FLEEKQASLWVQGDIFRSKLKNRPSSEGSINKILSGLDDMSIGGNLSKTQNMERFGEDNL 382
           FL +           +  K+KN+  + G  +K+              K  ++E+  E   
Sbjct: 287 FLGQLLD--------YEKKIKNQTGASGPKSKL--------------KLLHLEKPNEP-- 322

Query: 383 EDDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDDTKG-----HPRAV-SQPFRLSS 436
                     +++G +      + +   SP CA  +          HP +V S P    S
Sbjct: 323 -------VPAVSEGGQ------KSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPS 369

Query: 437 SLQGSAVTLKTSKMALSPSATAKRINRTSLSSGATVRSFSINSRLASSLGNLNAATDDPE 496
            L+ S +    S + LS +   +  N+   S    ++S S ++ +A+SL   +++ D  E
Sbjct: 370 LLEDSPLVQALSGLHLS-ADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALE 428

Query: 497 NKKTSSS 503
             K S++
Sbjct: 429 YYKPSTT 435


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 63/284 (22%), Positives = 112/284 (39%), Gaps = 23/284 (8%)

Query: 328  QASLWVQGDIFRSKLKNR-PSSEGSINKILSGLDDMSIGGNLSKTQNMERFGEDNLEDDD 386
            Q  L   GD+ + K + R     G+ N  LSG    S  G  S+T +     +   +D  
Sbjct: 954  QGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPS----NDGKSKDKP 1009

Query: 387  VEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDDTKGHPRAVSQPFRLSSSLQGSAVTL- 445
             + K   T+G K  +  S  +P T P+    S       R+ + P   +  +    + + 
Sbjct: 1010 PKRKKADTEG-KSPSHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIP 1068

Query: 446  KTSKMALSPSATAKRINRTSLSSGATVRSFSINSRLASSLGNLNAATDDPENKKTSSSSK 505
            K + M   PS+ ++  +  S+SS  +    S +S  +SS     + +   ++ K+  SS 
Sbjct: 1069 KGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSA----STSGKMKSSKSEGSSS 1124

Query: 506  AGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSSNSNGGNLNSPPGPHSAKTEEHTTIL 565
            +  ++S +++   GSS           ++Q   SS S G   +SP   H   +   +T +
Sbjct: 1125 SKLSSSMYSS--QGSS----------GSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKM 1172

Query: 566  RPSYTGLSSSSARFLSRSIPVSAQTPPPGPQNPECNFCALPSQP 609
            +P     S  +      +I  S   PP G          +P  P
Sbjct: 1173 KPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTP 1216



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 50/200 (25%), Positives = 88/200 (44%), Gaps = 18/200 (9%)

Query: 341  KLKNRPSSEGSINKILSGLDDMSIGGNLSKTQNMERFGEDNLEDDDVEMKNGITQGDKLR 400
            K+K+  S   S +K+ S +         S+++N  + G           K+G++ G    
Sbjct: 1113 KMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSG--GKPGSSPITKHGLSSGSSST 1170

Query: 401  ALKSQRQPRT--SPSCAFRSDDTKGHPRAVSQPFRLSSSLQGSAVTLKTSKMA--LSPSA 456
             +K Q +P +  +PS + + + +  H R      +L+S ++    T  +SK    +S  +
Sbjct: 1171 KMKPQGKPSSLMNPSLS-KPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGS 1229

Query: 457  TAKRINRTSLSSGATVRSFSINSRLASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNL 516
                ++ TS SSG        +S L SS G+L+  T    N  T+SSS    + S  ++ 
Sbjct: 1230 GGSHMSGTSSSSG-----MKSSSGLGSS-GSLSQKTPPSSNSCTASSSSFSSSGSSMSSS 1283

Query: 517  LN--GSSQ---PTTRNYPEL 531
             N  GSS+   P+    P L
Sbjct: 1284 QNQHGSSKGKSPSRNKKPSL 1303


>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
          Length = 188

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 268 ENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEE 326
           E  +G   +HC AG+ R+  L   Y+MK++  +  +   W + CRP  II P   F E+
Sbjct: 94  EMKQGRTLLHCAAGVSRSAALCLAYLMKYHAMSLLDAHTWTKSCRP--IIRPNSGFWEQ 150


>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 2/51 (3%)

Query: 274 IAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFL 324
           + +HC+AG+ R+ T++  Y+MKH R T  +   +++  RP  II P  +F+
Sbjct: 62  LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 110


>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
           sapiens]
          Length = 140

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 2/51 (3%)

Query: 274 IAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFL 324
           + +HC+AG+ R+ T++  Y+MKH R T  +   +++  RP  II P  +F+
Sbjct: 62  LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 110


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 18/51 (35%), Positives = 32/51 (62%), Gaps = 2/51 (3%)

Query: 274 IAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFL 324
           + +HC+AG+ R+ T++  Y+MKH R T  +   +++  RP  II P  +F+
Sbjct: 404 LLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRP--IISPNLNFM 452


>gi|239752523 PREDICTED: intestinal mucin-like, partial [Homo
           sapiens]
          Length = 514

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 40/177 (22%), Positives = 75/177 (42%), Gaps = 7/177 (3%)

Query: 418 SDDTKGHPRAVSQPFRLSSSLQGSA--VTLKTSKMALSPSATAKRINRTSLSSGATVRSF 475
           S D   H   ++     +S+L  +A   T  T+  + + S T +  + +  ++     +F
Sbjct: 336 SSDGTTHTETITSLPASTSTLHTTAESTTAHTTTTSFTTSTTMESPSSSVATTSTGQTTF 395

Query: 476 SINSRLASSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQ 535
           S ++   +    L   TD  E   T++ +      S  T     +S  T  ++P   N  
Sbjct: 396 SSSTATFTETTTLTPTTDFSEETLTTAMTSTPPITSSITPTNTVTSMTTMTSWPTATNTL 455

Query: 536 YNRSSNSNGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIPVSAQTPP 592
            + ++N     L+S P P + +T  HTT + P  T L ++    ++RS P +  T P
Sbjct: 456 SSLTTNI----LSSTPVPSTERTTSHTTNINPVST-LVTTLPTTITRSTPTAETTYP 507


>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
           sapiens]
          Length = 235

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 2/83 (2%)

Query: 263 FLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           F++ C    G   VHC AG+ R+ T++  YVM        +++  I+  RP  I  P   
Sbjct: 73  FIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKATRP--IANPNPG 130

Query: 323 FLEEKQASLWVQGDIFRSKLKNR 345
           F ++ +   W      R +L+ R
Sbjct: 131 FRQQLEEFGWASSQKLRRQLEER 153


>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
           sapiens]
          Length = 223

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 28/172 (16%)

Query: 165 DVDEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAV 224
           D +E+ +  R E  +   I+PG FL       KSK+             P  +KH +T +
Sbjct: 17  DAEEWTYPMRREMQE---ILPGLFLGPYSSAMKSKL-------------PVLQKHGITHI 60

Query: 225 VRLNKKIYEAKRFTDAGFEHYDLFFI--DGSTPSDNIVRRFLNICENTEGA------IAV 276
           + + + I     F    F+    + +      P +NI+R F    E  +G+      + V
Sbjct: 61  ICIRQNI--EANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLV 118

Query: 277 HCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQ 328
           H  AG+ R+   +  Y+M+ +   + +  A+++  R    I P   F+ + Q
Sbjct: 119 HGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERR--FCINPNAGFVHQLQ 168


>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 28/172 (16%)

Query: 165 DVDEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAV 224
           D +E+ +  R E  +   I+PG FL       KSK+             P  +KH +T +
Sbjct: 17  DAEEWTYPMRREMQE---ILPGLFLGPYSSAMKSKL-------------PVLQKHGITHI 60

Query: 225 VRLNKKIYEAKRFTDAGFEHYDLFFI--DGSTPSDNIVRRFLNICENTEGA------IAV 276
           + + + I     F    F+    + +      P +NI+R F    E  +G+      + V
Sbjct: 61  ICIRQNI--EANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLV 118

Query: 277 HCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQ 328
           H  AG+ R+   +  Y+M+ +   + +  A+++  R    I P   F+ + Q
Sbjct: 119 HGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERR--FCINPNAGFVHQLQ 168


>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
           sapiens]
          Length = 223

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 39/172 (22%), Positives = 72/172 (41%), Gaps = 28/172 (16%)

Query: 165 DVDEYEHYERVENGDFNWIVPGKFLAFSGPHPKSKIENGYPLHAPEAYFPYFKKHNVTAV 224
           D +E+ +  R E  +   I+PG FL       KSK+             P  +KH +T +
Sbjct: 17  DAEEWTYPMRREMQE---ILPGLFLGPYSSAMKSKL-------------PVLQKHGITHI 60

Query: 225 VRLNKKIYEAKRFTDAGFEHYDLFFI--DGSTPSDNIVRRFLNICENTEGA------IAV 276
           + + + I     F    F+    + +      P +NI+R F    E  +G+      + V
Sbjct: 61  ICIRQNI--EANFIKPNFQQLFRYLVLDIADNPVENIIRFFPMTKEFIDGSLQMGGKVLV 118

Query: 277 HCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHFLEEKQ 328
           H  AG+ R+   +  Y+M+ +   + +  A+++  R    I P   F+ + Q
Sbjct: 119 HGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERR--FCINPNAGFVHQLQ 168


>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
          Length = 403

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 32/121 (26%), Positives = 51/121 (42%), Gaps = 21/121 (17%)

Query: 200 IENGYPLHAPEAYFPYFKKHNVTAVVRL--NKKIYEAKRFTDAGFEHYDLF--------- 248
           I  G+P    E  +    ++N+  VVR   +K     K +      HYD           
Sbjct: 33  IAMGFPAERLEGVY----RNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQY 88

Query: 249 -FIDGSTPSDNIVRRFLN-----ICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHA 302
            F D + P   +++ F       + E+     A+HCKAG GRTG +I  Y++   +F  A
Sbjct: 89  PFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKA 148

Query: 303 E 303
           +
Sbjct: 149 Q 149


>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
          Length = 198

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 2/52 (3%)

Query: 272 GAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQHF 323
           GA  VHC AG+ R+ TL   Y+MK +     E   W++  RP  +I P   F
Sbjct: 105 GATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRP--VIRPNVGF 154


>gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo
           sapiens]
          Length = 1064

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 44/164 (26%), Positives = 65/164 (39%), Gaps = 20/164 (12%)

Query: 447 TSKMALSPSATAKR---INRTSLSSGATVRSFSINSRLASSLGNLNAATDDPENKKTSSS 503
           TS M  SPS T  R   I   + SS  +    + ++ ++S+            +  T+ S
Sbjct: 179 TSAMISSPSTTTARETPIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTMS 238

Query: 504 SKAGFTA--------SPFTNLLNGS----SQPTTRNYPELNNNQYNRSSNSNGGNLNSPP 551
               FT         SP T+ +  +    S  TT + P   N   +  SN     L+S P
Sbjct: 239 PTPVFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRPTATNTLSSLMSNI----LSSTP 294

Query: 552 GPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIPVSAQTPPPGP 595
            P +  T  HTT   P  T L ++    ++RS P S  T P  P
Sbjct: 295 VPSTEMTTSHTTDTNPLST-LVTTLPTTITRSTPTSETTYPASP 337



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 41/173 (23%), Positives = 70/173 (40%), Gaps = 29/173 (16%)

Query: 425 PRAVSQPFRLSSSLQGSAVTLKTSKMALSP--SATAKRINRTSLSSGATVRSFSINSRLA 482
           P A  +P  +   +    +  K  + + +P  S+TA     T+L+    + + S+ + + 
Sbjct: 433 PTADLKPELILLEVHDQRIQAKNPRYSQTPFTSSTATSPETTTLTCTNDISTESLTTAMT 492

Query: 483 SSLGNLNAATDDPENKKTSSSSKAGFTASPFTNLLNGSSQPTTRNYPELNNNQYNRSSNS 542
           S+   ++A T  P+   TS ++ A              S PTT N            S+ 
Sbjct: 493 STTPVISAIT--PKTTVTSMTTTA--------------SGPTTTN----------TLSSL 526

Query: 543 NGGNLNSPPGPHSAKTEEHTTILRPSYTGLSSSSARFLSRSIPVSAQTPPPGP 595
               L+S P P++     HTT   P  T L ++    ++RS P S  T P  P
Sbjct: 527 TSSILSSTPAPNTEVITSHTTTTTPPST-LVTTLPTAIARSTPTSETTYPISP 578


>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
          Length = 367

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 2/62 (3%)

Query: 263 FLNICENTEGAIAVHCKAGLGRTGTLIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           F++  +N  G + VHC+AG+ R+ T+   Y+M+  R    E   +++  R  SII P   
Sbjct: 243 FIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRR--SIISPNFS 300

Query: 323 FL 324
           F+
Sbjct: 301 FM 302


>gi|108802609 protein tyrosine phosphatase, non-receptor type 20
           isoform 4 [Homo sapiens]
          Length = 269

 Score = 38.9 bits (89), Expect = 0.014
 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 5/56 (8%)

Query: 272 GAIAVHCKAGLGRTGT-----LIACYVMKHYRFTHAEIIAWIRICRPGSIIGPQQH 322
           G + VHC AG+GRTG      ++ C ++K+  F   +I+A +R  R G +   +Q+
Sbjct: 196 GPMVVHCSAGIGRTGVFLCVDVVFCAIVKNCSFNIMDIVAQMREQRSGMVQTKEQY 251


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,869,740
Number of Sequences: 37866
Number of extensions: 1229468
Number of successful extensions: 5036
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 136
Number of HSP's that attempted gapping in prelim test: 4616
Number of HSP's gapped (non-prelim): 499
length of query: 623
length of database: 18,247,518
effective HSP length: 108
effective length of query: 515
effective length of database: 14,157,990
effective search space: 7291364850
effective search space used: 7291364850
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.