Search of human proteins with 15451889

Search of human proteins with 15451889

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15451889 glutamate decarboxylase 1 isoform GAD25 [Homo
sapiens]
         (224 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15451889 glutamate decarboxylase 1 isoform GAD25 [Homo sapiens]    458   e-129
gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens]    433   e-122
gi|197276620 glutamate decarboxylase 2 [Homo sapiens]                 171   5e-43
gi|4503875 glutamate decarboxylase 2 [Homo sapiens]                   171   5e-43
gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]       74   1e-13
gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]             64   8e-11
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  30   1.3  
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   30   2.2  
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]            29   2.8  
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]            29   2.8  
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]            29   2.8  
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]            29   2.8  
gi|126012573 low density lipoprotein-related protein 2 [Homo sap...    28   4.9  
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr...    28   8.3  

>gi|15451889 glutamate decarboxylase 1 isoform GAD25 [Homo sapiens]
          Length = 224

 Score =  458 bits (1178), Expect = e-129
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK 60
           MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK
Sbjct: 1   MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK 60

Query: 61  SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV 120
           SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
Sbjct: 61  SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV 120

Query: 121 VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV 180
           VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV
Sbjct: 121 VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV 180

Query: 181 RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMPSDMRECWLLR 224
           RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMPSDMRECWLLR
Sbjct: 181 RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMPSDMRECWLLR 224


>gi|58331246 glutamate decarboxylase 1 isoform GAD67 [Homo sapiens]
          Length = 594

 Score =  433 bits (1113), Expect = e-122
 Identities = 213/213 (100%), Positives = 213/213 (100%)

Query: 1   MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK 60
           MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK
Sbjct: 1   MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK 60

Query: 61  SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV 120
           SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
Sbjct: 61  SRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV 120

Query: 121 VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV 180
           VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV
Sbjct: 121 VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV 180

Query: 181 RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNM 213
           RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNM
Sbjct: 181 RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNM 213


>gi|197276620 glutamate decarboxylase 2 [Homo sapiens]
          Length = 585

 Score =  171 bits (433), Expect = 5e-43
 Identities = 87/188 (46%), Positives = 124/188 (65%), Gaps = 6/188 (3%)

Query: 26  PTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRD 85
           P T   WC VA   T  +G K+C  L       EK       +  +++    +C    + 
Sbjct: 23  PGTARAWCQVAQKFTGGIGNKLCALLYGD---AEKPAESGGSQPPRAAARKAACACDQKP 79

Query: 86  ARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPH 145
               + + +++ L A DLLPA +GE  T+ FL +V++ILL YV K+FDRSTKV+DFH+P+
Sbjct: 80  CSCSKVDVNYAFLHATDLLPACDGERPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPN 139

Query: 146 QLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWL 205
           +LL+    +N EL+D P++LE+IL+ C+ TLKY ++TGHPR+FNQLSTGLD++GLA +WL
Sbjct: 140 ELLQE---YNWELADQPQNLEEILMHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWL 196

Query: 206 TSTANTNM 213
           TSTANTNM
Sbjct: 197 TSTANTNM 204


>gi|4503875 glutamate decarboxylase 2 [Homo sapiens]
          Length = 585

 Score =  171 bits (433), Expect = 5e-43
 Identities = 87/188 (46%), Positives = 124/188 (65%), Gaps = 6/188 (3%)

Query: 26  PTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRD 85
           P T   WC VA   T  +G K+C  L       EK       +  +++    +C    + 
Sbjct: 23  PGTARAWCQVAQKFTGGIGNKLCALLYGD---AEKPAESGGSQPPRAAARKAACACDQKP 79

Query: 86  ARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPH 145
               + + +++ L A DLLPA +GE  T+ FL +V++ILL YV K+FDRSTKV+DFH+P+
Sbjct: 80  CSCSKVDVNYAFLHATDLLPACDGERPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPN 139

Query: 146 QLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWL 205
           +LL+    +N EL+D P++LE+IL+ C+ TLKY ++TGHPR+FNQLSTGLD++GLA +WL
Sbjct: 140 ELLQE---YNWELADQPQNLEEILMHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWL 196

Query: 206 TSTANTNM 213
           TSTANTNM
Sbjct: 197 TSTANTNM 204


>gi|194294551 cysteine sulfinic acid decarboxylase [Homo sapiens]
          Length = 520

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 44/113 (38%), Positives = 66/113 (58%), Gaps = 5/113 (4%)

Query: 102 DLLPAKNGEEQTVQFLLEVVD--ILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELS 159
           + LP+  G+   V+ LL  V   ++   ++K    S KV ++  P +L + ++   LEL 
Sbjct: 32  EALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLD---LELR 88

Query: 160 DHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTN 212
              ES +QIL  CR  ++Y V+TGHPRFFNQL +GLD   LAG  +T + NT+
Sbjct: 89  SQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTS 141


>gi|197383062 glutamate decarboxylase-like 1 [Homo sapiens]
          Length = 521

 Score = 64.3 bits (155), Expect = 8e-11
 Identities = 40/111 (36%), Positives = 59/111 (53%), Gaps = 12/111 (10%)

Query: 106 AKNGE---EQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHP 162
           AK GE   E+  + ++E V      V K  D + KV ++  P QL + ++   LE+ D  
Sbjct: 42  AKAGEKFVEEACRLIMEEV------VLKATDVNEKVCEWRPPEQLKQLLD---LEMRDSG 92

Query: 163 ESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNM 213
           E   ++L  CRD + Y V+T HPRFFNQL  GLD   L   ++T   N ++
Sbjct: 93  EPPHKLLELCRDVIHYSVKTNHPRFFNQLYAGLDYYSLVARFMTEALNPSV 143


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 12/107 (11%)

Query: 53  RTNSLEEKSRLVSAFKERQSSKNLL---------SCENSDRDARFRRTETDFSNLFARDL 103
           R   LE+ +      KERQ+ KN L           ENS+  A+ +  + D +NL  + L
Sbjct: 731 RLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDD-NNLLKQQL 789

Query: 104 LPAKNGEEQTVQFLL--EVVDILLNYVRKTFDRSTKVLDFHHPHQLL 148
              +N     V  L+  E V   ++ +R+     T  ++ H P  +L
Sbjct: 790 KDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVL 836


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 10/83 (12%)

Query: 73  SKNLLSCENSDRDARFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTF 132
           +K   + ENS RDA  ++ ET     FA   L  KN E +     +EV+D  L   R+  
Sbjct: 24  NKRHKAIENSARDAAVQKIETIIKEQFA---LEMKNKEHE-----IEVIDQRLIEARRMM 75

Query: 133 D--RSTKVLDFHHPHQLLEGMEG 153
           D  R+  V +++    LL+  EG
Sbjct: 76  DKLRACIVANYYASAGLLKVSEG 98


>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
          Length = 761

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 6/63 (9%)

Query: 38  GCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSN 97
           G  +KL L + G +      EEKS+L+  F   Q        E+S +DA F +  T+  +
Sbjct: 73  GREKKLALMLSGLI------EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQS 126

Query: 98  LFA 100
           L A
Sbjct: 127 LEA 129


>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
          Length = 804

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 6/63 (9%)

Query: 38  GCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSN 97
           G  +KL L + G +      EEKS+L+  F   Q        E+S +DA F +  T+  +
Sbjct: 73  GREKKLALMLSGLI------EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQS 126

Query: 98  LFA 100
           L A
Sbjct: 127 LEA 129


>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
          Length = 775

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 6/63 (9%)

Query: 38  GCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSN 97
           G  +KL L + G +      EEKS+L+  F   Q        E+S +DA F +  T+  +
Sbjct: 44  GREKKLALMLSGLI------EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQS 97

Query: 98  LFA 100
           L A
Sbjct: 98  LEA 100


>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
          Length = 792

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 20/63 (31%), Positives = 30/63 (47%), Gaps = 6/63 (9%)

Query: 38  GCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDARFRRTETDFSN 97
           G  +KL L + G +      EEKS+L+  F   Q        E+S +DA F +  T+  +
Sbjct: 61  GREKKLALMLSGLI------EEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQS 114

Query: 98  LFA 100
           L A
Sbjct: 115 LEA 117


>gi|126012573 low density lipoprotein-related protein 2 [Homo sapiens]
          Length = 4655

 Score = 28.5 bits (62), Expect = 4.9
 Identities = 13/34 (38%), Positives = 20/34 (58%)

Query: 147  LLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV 180
            +L  + GF+LELSDH E++  +    R+ L   V
Sbjct: 2069 MLSAIRGFSLELSDHSETMVPVAGQGRNALHVDV 2102


>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
           precursor [Homo sapiens]
          Length = 728

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 18/84 (21%), Positives = 34/84 (40%), Gaps = 10/84 (11%)

Query: 137 KVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLD 196
           K++D   P +L  G+  F         S    L   +  +KY  +  + +  N  +TG+ 
Sbjct: 363 KIVDCRAPGELEHGLITF---------STRNNLTTYKSEIKYSCQEPYYKMLNN-NTGIY 412

Query: 197 IIGLAGEWLTSTANTNMPSDMREC 220
                G W+      ++P+ + EC
Sbjct: 413 TCSAQGVWMNKVLGRSLPTCLPEC 436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,103,746
Number of Sequences: 37866
Number of extensions: 322720
Number of successful extensions: 1038
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1027
Number of HSP's gapped (non-prelim): 14
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.