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Search of human proteins with 153945761
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153945761 endothelin converting enzyme 2 isoform A [Homo
sapiens]
(883 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153945761 endothelin converting enzyme 2 isoform A [Homo sapi... 1800 0.0
gi|153945836 endothelin converting enzyme 2 isoform E [Homo sapi... 1475 0.0
gi|153945771 endothelin converting enzyme 2 isoform D [Homo sapi... 1475 0.0
gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens] 1474 0.0
gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo sapi... 985 0.0
gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo sapi... 984 0.0
gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo sapi... 984 0.0
gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens] 984 0.0
gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens] 548 e-156
gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens] 529 e-150
gi|116256333 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|116256331 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|116256327 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|116256329 membrane metallo-endopeptidase [Homo sapiens] 487 e-137
gi|90403592 phosphate-regulating neutral endopeptidase [Homo sap... 459 e-129
gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens] 359 5e-99
gi|153945707 endothelin converting enzyme 2 isoform C [Homo sapi... 332 7e-91
gi|42542403 CGI-01 protein isoform 1 [Homo sapiens] 108 2e-23
gi|55956895 CGI-01 protein isoform 3 [Homo sapiens] 107 5e-23
gi|42542405 CGI-01 protein isoform 2 [Homo sapiens] 54 6e-07
gi|58219056 methyltransferase like 10 [Homo sapiens] 48 4e-05
gi|112734863 methyltransferase like 12 [Homo sapiens] 42 0.002
gi|124487387 ring finger protein 207 [Homo sapiens] 33 1.5
gi|239753431 PREDICTED: similar to endothelin converting enzyme-... 32 2.6
gi|239747995 PREDICTED: hypothetical protein XP_002346505 [Homo ... 32 2.6
gi|239741893 PREDICTED: hypothetical protein XP_002342317 [Homo ... 32 2.6
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 31 4.4
gi|15553097 hypothetical protein MGC9084 [Homo sapiens] 31 5.8
gi|4505697 pendrin [Homo sapiens] 30 9.9
gi|83641876 serine carboxypeptidase vitellogenic-like [Homo sapi... 30 9.9
>gi|153945761 endothelin converting enzyme 2 isoform A [Homo
sapiens]
Length = 883
Score = 1800 bits (4661), Expect = 0.0
Identities = 883/883 (100%), Positives = 883/883 (100%)
Query: 1 MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED 60
MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED
Sbjct: 1 MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED 60
Query: 61 RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP 120
RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP
Sbjct: 61 RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP 120
Query: 121 SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVGFQKGTRQLLGSRTQLELV 180
SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVGFQKGTRQLLGSRTQLELV
Sbjct: 121 SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVGFQKGTRQLLGSRTQLELV 180
Query: 181 LAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQ 240
LAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQ
Sbjct: 181 LAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQ 240
Query: 241 FSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCL 300
FSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCL
Sbjct: 241 FSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCL 300
Query: 301 QVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSK 360
QVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSK
Sbjct: 301 QVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSK 360
Query: 361 SSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQV 420
SSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQV
Sbjct: 361 SSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQV 420
Query: 421 LELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPV 480
LELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPV
Sbjct: 421 LELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPV 480
Query: 481 VVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKS 540
VVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKS
Sbjct: 481 VVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKS 540
Query: 541 CVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDE 600
CVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDE
Sbjct: 541 CVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDE 600
Query: 601 KTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMAD 660
KTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMAD
Sbjct: 601 KTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMAD 660
Query: 661 QLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGH 720
QLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGH
Sbjct: 661 QLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGH 720
Query: 721 ELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGE 780
ELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGE
Sbjct: 721 ELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGE 780
Query: 781 NIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGL 840
NIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGL
Sbjct: 781 NIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGL 840
Query: 841 VTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 883
VTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW
Sbjct: 841 VTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 883
>gi|153945836 endothelin converting enzyme 2 isoform E [Homo
sapiens]
Length = 765
Score = 1475 bits (3818), Expect = 0.0
Identities = 724/724 (100%), Positives = 724/724 (100%)
Query: 160 EVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIR 219
EVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIR
Sbjct: 42 EVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIR 101
Query: 220 VAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLEN 279
VAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLEN
Sbjct: 102 VAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLEN 161
Query: 280 TTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLK 339
TTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLK
Sbjct: 162 TTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLK 221
Query: 340 AVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYM 399
AVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYM
Sbjct: 222 AVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYM 281
Query: 400 EELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSM 459
EELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSM
Sbjct: 282 EELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSM 341
Query: 460 DWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSL 519
DWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSL
Sbjct: 342 DWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSL 401
Query: 520 DRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEG 579
DRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEG
Sbjct: 402 DRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEG 461
Query: 580 MISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEIS 639
MISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEIS
Sbjct: 462 MISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEIS 521
Query: 640 EDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAP 699
EDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAP
Sbjct: 522 EDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAP 581
Query: 700 FYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACME 759
FYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACME
Sbjct: 582 FYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACME 641
Query: 760 EQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLF 819
EQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLF
Sbjct: 642 EQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLF 701
Query: 820 FVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQL 879
FVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQL
Sbjct: 702 FVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQL 761
Query: 880 CEVW 883
CEVW
Sbjct: 762 CEVW 765
>gi|153945771 endothelin converting enzyme 2 isoform D [Homo
sapiens]
Length = 811
Score = 1475 bits (3818), Expect = 0.0
Identities = 726/742 (97%), Positives = 731/742 (98%), Gaps = 2/742 (0%)
Query: 144 WTVSSEGVHTVDQVLSE--VGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGV 201
W V+ + ++ + S VGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGV
Sbjct: 70 WRVTCPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGV 129
Query: 202 QYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNT 261
QYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNT
Sbjct: 130 QYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNT 189
Query: 262 FNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIG 321
FNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIG
Sbjct: 190 FNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIG 249
Query: 322 GWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 381
GWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY
Sbjct: 250 GWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 309
Query: 382 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEE 441
YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEE
Sbjct: 310 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEE 369
Query: 442 KIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPS 501
KIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPS
Sbjct: 370 KIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPS 429
Query: 502 ILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALG 561
ILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALG
Sbjct: 430 ILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALG 489
Query: 562 SLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPD 621
SLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPD
Sbjct: 490 SLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPD 549
Query: 622 FILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAY 681
FILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAY
Sbjct: 550 FILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAY 609
Query: 682 YLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRP 741
YLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRP
Sbjct: 610 YLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRP 669
Query: 742 WWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRK 801
WWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRK
Sbjct: 670 WWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRK 729
Query: 802 HGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRD 861
HGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRD
Sbjct: 730 HGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRD 789
Query: 862 FLRHFGCPVGSPMNPGQLCEVW 883
FLRHFGCPVGSPMNPGQLCEVW
Sbjct: 790 FLRHFGCPVGSPMNPGQLCEVW 811
>gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens]
Length = 736
Score = 1474 bits (3817), Expect = 0.0
Identities = 724/725 (99%), Positives = 724/725 (99%)
Query: 159 SEVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACI 218
S VGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACI
Sbjct: 12 SNVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACI 71
Query: 219 RVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLE 278
RVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLE
Sbjct: 72 RVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLE 131
Query: 279 NTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVL 338
NTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVL
Sbjct: 132 NTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVL 191
Query: 339 KAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDY 398
KAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDY
Sbjct: 192 KAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDY 251
Query: 399 MEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPS 458
MEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPS
Sbjct: 252 MEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPS 311
Query: 459 MDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSS 518
MDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSS
Sbjct: 312 MDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSS 371
Query: 519 LDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAE 578
LDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAE
Sbjct: 372 LDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAE 431
Query: 579 GMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEI 638
GMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEI
Sbjct: 432 GMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEI 491
Query: 639 SEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQA 698
SEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQA
Sbjct: 492 SEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQA 551
Query: 699 PFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACM 758
PFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACM
Sbjct: 552 PFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACM 611
Query: 759 EEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQL 818
EEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQL
Sbjct: 612 EEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQL 671
Query: 819 FFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQ 878
FFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQ
Sbjct: 672 FFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQ 731
Query: 879 LCEVW 883
LCEVW
Sbjct: 732 LCEVW 736
>gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo
sapiens]
Length = 758
Score = 985 bits (2546), Expect = 0.0
Identities = 470/748 (62%), Positives = 590/748 (78%), Gaps = 4/748 (0%)
Query: 137 LAGERDPWTVSSEGVHTVDQVLSEVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCL 196
L G+R P SS + ++ + G R +RTQ+E L +LLAA L+ CL
Sbjct: 14 LQGKRGPGLTSSPPLLPPSLQVNFHSPRSGQR-CWAARTQVEKRLVVLVVLLAAGLVACL 72
Query: 197 VALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGR 256
ALG+QY + S S CL+EAC+ V IL S+D V PC DF+ ++CGGWI+ NP+PDG
Sbjct: 73 AALGIQY-QTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGH 131
Query: 257 SRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDL 316
SRW TF++LW+ NQAI+KHLLEN+T S SEAE+K Q +Y +C+ RIEEL A+PL +L
Sbjct: 132 SRWGTFSNLWEHNQAIIKHLLENSTA-SVSEAERKAQVYYRACMNETRIEELRAKPLMEL 190
Query: 317 IEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFL 376
IE++GGWNITGPW +DNF + L+ V YR +PFF+VY+SADSK+SNSNVIQVDQSGL L
Sbjct: 191 IERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGL 250
Query: 377 PSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTST-REQMQQVLELEIQLANITVPQD 435
PSRDYYLN+T NEKVLT YL+YM +LG LLGG R QMQQ+L+ E LANIT+PQ+
Sbjct: 251 PSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQE 310
Query: 436 QRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELI 495
+RRDEE IYHK++ +ELQ LAP+++WL FL+ + P+E+++SEP+VVY +YL+Q+S LI
Sbjct: 311 KRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPVEINESEPIVVYDKEYLEQISTLI 370
Query: 496 NRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDA 555
N T+ +LNNY+IWNLV+KT+S LD+RF+ A EK +E +YGTKK+C+PRW+ C+S+T++
Sbjct: 371 NTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENN 430
Query: 556 LGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYD 615
LGFALG +FVKATF SK IA +I EI+ AFEE+L L WMDE+TR++AKEKADAIY+
Sbjct: 431 LGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYN 490
Query: 616 MIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTP 675
MIG+P+FI++PKELD V++ Y D +F+N + +NFS +V ADQLRK P+RDQWSMTP
Sbjct: 491 MIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTP 550
Query: 676 QTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDK 735
VNAYY PTKNEIVFPAGILQAPFY R+ PKALNFGGIGVV+GHELTHAFDDQGREYDK
Sbjct: 551 PMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDK 610
Query: 736 EGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAY 795
+GNLRPWW+N S+ AF+ T CM EQY+ Y VNGE +NGR TLGENIADNGGLKAAY AY
Sbjct: 611 DGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAY 670
Query: 796 KAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGT 855
+ W++K+G E LP +GLTN+QLFF+GFAQVWCSVRTPESSHEGL+TDPHSP+RFRV+G+
Sbjct: 671 QNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGS 730
Query: 856 LSNSRDFLRHFGCPVGSPMNPGQLCEVW 883
LSNS++F HF CP GSPMNP CEVW
Sbjct: 731 LSNSKEFSEHFRCPPGSPMNPPHKCEVW 758
>gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo
sapiens]
Length = 767
Score = 984 bits (2544), Expect = 0.0
Identities = 462/712 (64%), Positives = 577/712 (81%), Gaps = 3/712 (0%)
Query: 173 SRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGV 232
+RTQ+E L +LLAA L+ CL ALG+QY + S S CL+EAC+ V IL S+D V
Sbjct: 58 ARTQVEKRLVVLVVLLAAGLVACLAALGIQY-QTRSPSVCLSEACVSVTSSILSSMDPTV 116
Query: 233 SPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKT 292
PC DF+ ++CGGWI+ NP+PDG SRW TF++LW+ NQAI+KHLLEN+T S SEAE+K
Sbjct: 117 DPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTA-SVSEAERKA 175
Query: 293 QRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFT 352
Q +Y +C+ RIEEL A+PL +LIE++GGWNITGPW +DNF + L+ V YR +PFF+
Sbjct: 176 QVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFS 235
Query: 353 VYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTS 412
VY+SADSK+SNSNVIQVDQSGL LPSRDYYLN+T NEKVLT YL+YM +LG LLGG
Sbjct: 236 VYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEE 295
Query: 413 T-REQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSP 471
R QMQQ+L+ E LANIT+PQ++RRDEE IYHK++ +ELQ LAP+++WL FL+ + P
Sbjct: 296 AIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYP 355
Query: 472 LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLL 531
+E+++SEP+VVY +YL+Q+S LIN T+ +LNNY+IWNLV+KT+S LD+RF+ A EK +
Sbjct: 356 VEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFM 415
Query: 532 ETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEA 591
E +YGTKK+C+PRW+ C+S+T++ LGFALG +FVKATF SK IA +I EI+ AFEE+
Sbjct: 416 EVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEES 475
Query: 592 LGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLY 651
L L WMDE+TR++AKEKADAIY+MIG+P+FI++PKELD V++ Y D +F+N + +
Sbjct: 476 LSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFF 535
Query: 652 NFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNF 711
NFS +V ADQLRK P+RDQWSMTP VNAYY PTKNEIVFPAGILQAPFY R+ PKALNF
Sbjct: 536 NFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNF 595
Query: 712 GGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGER 771
GGIGVV+GHELTHAFDDQGREYDK+GNLRPWW+N S+ AF+ T CM EQY+ Y VNGE
Sbjct: 596 GGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEP 655
Query: 772 LNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVR 831
+NGR TLGENIADNGGLKAAY AY+ W++K+G E LP +GLTN+QLFF+GFAQVWCSVR
Sbjct: 656 VNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVR 715
Query: 832 TPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 883
TPESSHEGL+TDPHSP+RFRV+G+LSNS++F HF CP GSPMNP CEVW
Sbjct: 716 TPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 767
>gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo
sapiens]
Length = 754
Score = 984 bits (2544), Expect = 0.0
Identities = 462/712 (64%), Positives = 577/712 (81%), Gaps = 3/712 (0%)
Query: 173 SRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGV 232
+RTQ+E L +LLAA L+ CL ALG+QY + S S CL+EAC+ V IL S+D V
Sbjct: 45 ARTQVEKRLVVLVVLLAAGLVACLAALGIQY-QTRSPSVCLSEACVSVTSSILSSMDPTV 103
Query: 233 SPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKT 292
PC DF+ ++CGGWI+ NP+PDG SRW TF++LW+ NQAI+KHLLEN+T S SEAE+K
Sbjct: 104 DPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTA-SVSEAERKA 162
Query: 293 QRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFT 352
Q +Y +C+ RIEEL A+PL +LIE++GGWNITGPW +DNF + L+ V YR +PFF+
Sbjct: 163 QVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFS 222
Query: 353 VYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTS 412
VY+SADSK+SNSNVIQVDQSGL LPSRDYYLN+T NEKVLT YL+YM +LG LLGG
Sbjct: 223 VYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEE 282
Query: 413 T-REQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSP 471
R QMQQ+L+ E LANIT+PQ++RRDEE IYHK++ +ELQ LAP+++WL FL+ + P
Sbjct: 283 AIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYP 342
Query: 472 LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLL 531
+E+++SEP+VVY +YL+Q+S LIN T+ +LNNY+IWNLV+KT+S LD+RF+ A EK +
Sbjct: 343 VEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFM 402
Query: 532 ETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEA 591
E +YGTKK+C+PRW+ C+S+T++ LGFALG +FVKATF SK IA +I EI+ AFEE+
Sbjct: 403 EVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEES 462
Query: 592 LGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLY 651
L L WMDE+TR++AKEKADAIY+MIG+P+FI++PKELD V++ Y D +F+N + +
Sbjct: 463 LSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFF 522
Query: 652 NFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNF 711
NFS +V ADQLRK P+RDQWSMTP VNAYY PTKNEIVFPAGILQAPFY R+ PKALNF
Sbjct: 523 NFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNF 582
Query: 712 GGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGER 771
GGIGVV+GHELTHAFDDQGREYDK+GNLRPWW+N S+ AF+ T CM EQY+ Y VNGE
Sbjct: 583 GGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEP 642
Query: 772 LNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVR 831
+NGR TLGENIADNGGLKAAY AY+ W++K+G E LP +GLTN+QLFF+GFAQVWCSVR
Sbjct: 643 VNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVR 702
Query: 832 TPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 883
TPESSHEGL+TDPHSP+RFRV+G+LSNS++F HF CP GSPMNP CEVW
Sbjct: 703 TPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 754
>gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens]
Length = 770
Score = 984 bits (2544), Expect = 0.0
Identities = 462/712 (64%), Positives = 577/712 (81%), Gaps = 3/712 (0%)
Query: 173 SRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGV 232
+RTQ+E L +LLAA L+ CL ALG+QY + S S CL+EAC+ V IL S+D V
Sbjct: 61 ARTQVEKRLVVLVVLLAAGLVACLAALGIQY-QTRSPSVCLSEACVSVTSSILSSMDPTV 119
Query: 233 SPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKT 292
PC DF+ ++CGGWI+ NP+PDG SRW TF++LW+ NQAI+KHLLEN+T S SEAE+K
Sbjct: 120 DPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLENSTA-SVSEAERKA 178
Query: 293 QRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFT 352
Q +Y +C+ RIEEL A+PL +LIE++GGWNITGPW +DNF + L+ V YR +PFF+
Sbjct: 179 QVYYRACMNETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFS 238
Query: 353 VYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTS 412
VY+SADSK+SNSNVIQVDQSGL LPSRDYYLN+T NEKVLT YL+YM +LG LLGG
Sbjct: 239 VYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGGDEE 298
Query: 413 T-REQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSP 471
R QMQQ+L+ E LANIT+PQ++RRDEE IYHK++ +ELQ LAP+++WL FL+ + P
Sbjct: 299 AIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYP 358
Query: 472 LELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLL 531
+E+++SEP+VVY +YL+Q+S LIN T+ +LNNY+IWNLV+KT+S LD+RF+ A EK +
Sbjct: 359 VEINESEPIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFM 418
Query: 532 ETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEA 591
E +YGTKK+C+PRW+ C+S+T++ LGFALG +FVKATF SK IA +I EI+ AFEE+
Sbjct: 419 EVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEES 478
Query: 592 LGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLY 651
L L WMDE+TR++AKEKADAIY+MIG+P+FI++PKELD V++ Y D +F+N + +
Sbjct: 479 LSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFF 538
Query: 652 NFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNF 711
NFS +V ADQLRK P+RDQWSMTP VNAYY PTKNEIVFPAGILQAPFY R+ PKALNF
Sbjct: 539 NFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNF 598
Query: 712 GGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGER 771
GGIGVV+GHELTHAFDDQGREYDK+GNLRPWW+N S+ AF+ T CM EQY+ Y VNGE
Sbjct: 599 GGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEP 658
Query: 772 LNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVR 831
+NGR TLGENIADNGGLKAAY AY+ W++K+G E LP +GLTN+QLFF+GFAQVWCSVR
Sbjct: 659 VNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVR 718
Query: 832 TPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 883
TPESSHEGL+TDPHSP+RFRV+G+LSNS++F HF CP GSPMNP CEVW
Sbjct: 719 TPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 770
>gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens]
Length = 779
Score = 548 bits (1412), Expect = e-156
Identities = 298/757 (39%), Positives = 429/757 (56%), Gaps = 56/757 (7%)
Query: 181 LAGASLLLAALLLGCLVALGVQY-------------------------HRDPS------- 208
L G LLL L+ LVALGV Y R P
Sbjct: 25 LEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLASRLCFLQEERTFVKRKPRGIPEAQE 84
Query: 209 -HSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWD 267
C T C+ A +IL+++D PC+DFYQF+CGGW+RR+ +P+ SR++ F+ L D
Sbjct: 85 VSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRD 144
Query: 268 QNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNIT- 326
+ + ILK +LEN+T E K + Y SC+ IE+ G+QPL D++E +GGW +
Sbjct: 145 ELEVILKAVLENSTAKDRPAVE-KARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAM 203
Query: 327 GPWDQDNFME-----VLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 381
W++ +E L + + ++I D ++S+ ++I +DQ L +PSR+Y
Sbjct: 204 DRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREY 263
Query: 382 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTR------EQMQQVLELEIQLANITVPQD 435
Y N +N KV AYL +M + LL R E M QVLELE QLA TVPQ+
Sbjct: 264 YFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQE 323
Query: 436 QRRDEEKIYHKMSISELQAL--APSMDWLEFLSFLLSP--LELSDSEPVVVYGMDYLQQV 491
+R D +YH+M + ELQ+ +W F+ +LS ++L E VVVYG+ YLQ +
Sbjct: 324 ERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
Query: 492 SELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISN 551
+I+ + NYL+W LV SL +RF+ + + L+GT V RW+ C+
Sbjct: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEV-RWRECVGY 442
Query: 552 TDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKAD 611
+ + A+GSL+V+ F SK + +I ++RT F E L +L WMDE++++ A+EKA
Sbjct: 443 VNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAM 502
Query: 612 AIYDMIGFPDFILEP--KELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRD 669
+I + IG PD+ILE + LD+ Y SED +F+N L A+ +LR+ +
Sbjct: 503 SIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPN 562
Query: 670 QWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQ 729
W + VNA+Y P +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+GHE+TH FDD
Sbjct: 563 LWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDN 622
Query: 730 GREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQ---VNGERLNGRQTLGENIADNG 786
GR +DK GN+ WW N S FR + CM QY Y + + +NG TLGENIADNG
Sbjct: 623 GRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNG 682
Query: 787 GLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHS 846
G++ AY AY W+ + G++QQLP + LT+ QLFF+ +AQVWC PE + + + TD HS
Sbjct: 683 GVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHS 742
Query: 847 PARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 883
P ++RVLG+L N F F C G+PM+P + C VW
Sbjct: 743 PLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
>gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens]
Length = 775
Score = 529 bits (1362), Expect = e-150
Identities = 267/681 (39%), Positives = 408/681 (59%), Gaps = 20/681 (2%)
Query: 215 EACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILK 274
+A R A + +LD + PC+DFY F+CGGW+RR+ +PD + + T ++ +QN+ L+
Sbjct: 103 KAFARAARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLTYGTIAAIGEQNEERLR 162
Query: 275 HLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGP------ 328
LL A++K + F+ SCL + IE LG +P+ ++IE GGW++ G
Sbjct: 163 RLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIEDCGGWDLGGAEERPGV 222
Query: 329 ---WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNR 385
WD + +L G Y A F++ +S D ++S+ VI++DQ GL LP R YL +
Sbjct: 223 AARWDLNR---LLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQDGLTLPERTLYLAQ 279
Query: 386 TAN-EKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQ--DQRRDEEK 442
+ EK+L AY +ME + LLG + ++ Q++L++E QLANITV + D RRD
Sbjct: 280 DEDSEKILAAYRVFMERVLSLLGA--DAVEQKAQEILQVEQQLANITVSEHDDLRRDVSS 337
Query: 443 IYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSI 502
+Y+K+++ +LQ + P + W L + + S+ E VV+ DY+QQVS+LI T +
Sbjct: 338 MYNKVTLGQLQKITPHLRWKWLLDQIFQE-DFSEEEEVVLLATDYMQQVSQLIRSTPHRV 396
Query: 503 LNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGS 562
L+NYL+W +V + L F A +L + + G+ K + C+ + G ALG+
Sbjct: 397 LHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGSDKP-QELARVCLGQANRHFGMALGA 455
Query: 563 LFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDF 622
LFV F SK + ++ +I+ + L +L WMD +TR AA+ K + M+G+PDF
Sbjct: 456 LFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWMDAETRAAARAKLQYMMVMVGYPDF 515
Query: 623 ILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYY 682
+L+P +D Y+ +E+ E ++F+N+LN FS ++ ++R+ + W + PQ +NAYY
Sbjct: 516 LLKPDAVDKEYE-FEVHEKTYFKNILNSIRFSIQLSVKKIRQEVDKSTWLLPPQALNAYY 574
Query: 683 LPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPW 742
LP KN++VFPAGILQ Y + P++LN+GGIG ++GHELTH +DD G +YD+ GNL W
Sbjct: 575 LPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDRSGNLLHW 634
Query: 743 WQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKH 802
W S + F C+ Y+ + V +R+NG+ TLGENIAD GGLK AY+AY+ W+R+H
Sbjct: 635 WTEASYSRFLRKAECIVRLYDNFTVYNQRVNGKHTLGENIADMGGLKLAYHAYQKWVREH 694
Query: 803 GEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDF 862
G E LP + T+ QLFF+ FAQ WC R +S + ++TD H+P +RVLG++S +F
Sbjct: 695 GPEHPLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVLGSVSQFEEF 754
Query: 863 LRHFGCPVGSPMNPGQLCEVW 883
R F CP SPMNP C VW
Sbjct: 755 GRAFHCPKDSPMNPAHKCSVW 775
>gi|116256333 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 175 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 234
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 235 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 294
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 295 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 348
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 349 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 408
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 409 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 456
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 457 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 514
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 515 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 574
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 575 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 633
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 634 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 693
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 694 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 753
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 754 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 810
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 811 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 870
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 871 GSPMNPGQLCEVW 883
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|116256331 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 175 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 234
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 235 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 294
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 295 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 348
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 349 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 408
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 409 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 456
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 457 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 514
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 515 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 574
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 575 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 633
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 634 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 693
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 694 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 753
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 754 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 810
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 811 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 870
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 871 GSPMNPGQLCEVW 883
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|116256327 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 175 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 234
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 235 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 294
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 295 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 348
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 349 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 408
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 409 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 456
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 457 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 514
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 515 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 574
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 575 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 633
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 634 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 693
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 694 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 753
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 754 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 810
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 811 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 870
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 871 GSPMNPGQLCEVW 883
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|116256329 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 487 bits (1254), Expect = e-137
Identities = 263/733 (35%), Positives = 412/733 (56%), Gaps = 31/733 (4%)
Query: 175 TQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSP 234
T LE+ L+ LLL + + ++AL Y C + CI+ A ++++++D P
Sbjct: 25 TPLEISLSVLVLLLTIIAV-TMIALYATY----DDGICKSSDCIKSAARLIQNMDATTEP 79
Query: 235 CEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQR 294
C DF++++CGGW++RN +P+ SR+ F+ L D+ + +LK +L+ A QK +
Sbjct: 80 CTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELEVVLKDVLQEPK-TEDIVAVQKAKA 138
Query: 295 FYLSCLQVERIEELGAQPLRDLIEKIGGWNI-TGPWDQDNFME--VLKAVA---GTYRAT 348
Y SC+ I+ G +PL L+ I GW + T W+Q KA+A Y
Sbjct: 139 LYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWEQKYGASWTAEKAIAQLNSKYGKK 198
Query: 349 PFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGG 408
+++ D K+S ++VI +DQ L LPSRDYY ++ TAY+D+M + L+
Sbjct: 199 VLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECTGIYKEACTAYVDFMISVARLIRQ 258
Query: 409 R---PTSTRE---QMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQ------ALA 456
P + +M +V+ELE ++AN T + R D +Y+KM+++++Q
Sbjct: 259 EERLPIDENQLALEMNKVMELEKEIANATAKPEDRNDPMLLYNKMTLAQIQNNFSLEING 318
Query: 457 PSMDWLEFLSFLLSPLELS--DSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQK 514
WL F + ++S + +S + E VVVY +YL ++ ++ + L N + W +
Sbjct: 319 KPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKLKPILTKYSARDLQNLMSWRFIMD 378
Query: 515 TTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSK 574
SSL R ++ ++ + LYGT W+ C + + + A+G L+V+A F +SK
Sbjct: 379 LVSSLSRTYKESRNAFRKALYGTTSETAT-WRRCANYVNGNMENAVGRLYVEAAFAGESK 437
Query: 575 EIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILE-PKELDDVY 633
+ E +I++IR F + L L WMD +T++ A+EKA AI + IG+PD I+ +L++ Y
Sbjct: 438 HVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALAIKERIGYPDDIVSNDNKLNNEY 497
Query: 634 DGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPA 693
ED +F+N++ FS +LR+ +D+W VNA+Y +N+IVFPA
Sbjct: 498 LELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPA 557
Query: 694 GILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRN 753
GILQ PF++ +LN+GGIG+V+GHE+TH FDD GR ++K+G+L WW +S + F+
Sbjct: 558 GILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSASNFKE 617
Query: 754 HTACMEEQYNQYQ---VNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPA 810
+ CM QY + G+ LNG TLGENIADNGGL AY AY+ +++K+GEE+ LP
Sbjct: 618 QSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGLGQAYRAYQNYIKKNGEEKLLPG 677
Query: 811 VGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPV 870
+ L + QLFF+ FAQVWC PE + + TD HSP FR++GTL NS +F F C
Sbjct: 678 LDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFSEAFHCRK 737
Query: 871 GSPMNPGQLCEVW 883
S MNP + C VW
Sbjct: 738 NSYMNPEKKCRVW 750
>gi|90403592 phosphate-regulating neutral endopeptidase [Homo
sapiens]
Length = 749
Score = 459 bits (1182), Expect = e-129
Identities = 262/746 (35%), Positives = 407/746 (54%), Gaps = 32/746 (4%)
Query: 164 QKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGK 223
+ G + G+R L +V G +L+L +L LV+ G+ CL CI A
Sbjct: 10 ETGKKANRGTRIAL-VVFVGGTLVLGTILF--LVSQGL-LSLQAKQEYCLKPECIEAAAA 65
Query: 224 ILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENT-TF 282
IL ++ V PC++F++F+C GWI NP+P+ + + L LK LLE + +
Sbjct: 66 ILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSYGVYPWLRHNVDLKLKELLEKSISR 125
Query: 283 NSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIG-GWNIT-------GPWDQDNF 334
+EA QK + Y SC+ + IE+ A+PL ++ W + G W + F
Sbjct: 126 RRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILRHSPFRWPVLESNIGPEGVWSERKF 185
Query: 335 --MEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYL-NRTANEKV 391
++ L G Y + F +Y+S D K+SN +++++DQ+ L L R+ YL N T +
Sbjct: 186 SLLQTLATFRGQYSNSVFIRLYVSPDDKASNEHILKLDQATLSLAVREDYLDNSTEAKSY 245
Query: 392 LTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISE 451
A +M + +LLG + M+ VL LEI++A I +P + R E +Y+KM+ISE
Sbjct: 246 RDALYKFMVDTAVLLGANSSRAEHDMKSVLRLEIKIAEIMIPHENRTSEA-MYNKMNISE 304
Query: 452 LQALAPSMDWLEFLSFLLSPL------ELSDSEPVVVYGMDYLQQVSELINRTEPSILNN 505
L A+ P DWL ++ ++ ++S SE VVV Y + + ++ + N
Sbjct: 305 LSAMIPQFDWLGYIKKVIDTRLYPHLKDISPSENVVVRVPQYFKDLFRILGSERKKTIAN 364
Query: 506 YLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFV 565
YL+W +V +L RRF+ + + GT + +P+W C++ + AL + +G +FV
Sbjct: 365 YLVWRMVYSRIPNLSRRFQYRWLEFSRVIQGTT-TLLPQWDKCVNFIESALPYVVGKMFV 423
Query: 566 KATFDRQSKEIAEGMISEIRTAFEEALG-QLVWMDEKTRQAAKEKADAIYDMIGFPDFIL 624
F KE+ E ++ +R AF + L + WMD T++ AKEKA A+ +G+P+FI+
Sbjct: 424 DVYFQEDKKEMMEELVEGVRWAFIDMLEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIM 483
Query: 625 EPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLP 684
+++ + SE +F N+L + A+ LRK + +W P TVNA+Y
Sbjct: 484 NDTHVNEDLKAIKFSEADYFGNVLQTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSA 543
Query: 685 TKNEIVFPAGILQAPFY-ARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWW 743
+ N+I FPAG LQ PF+ +P++L++G IGV++GHE TH FD+ GR+YDK GNL PWW
Sbjct: 544 STNQIRFPAGELQKPFFWGTEYPRSLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWW 603
Query: 744 QNESLAAFRNHTACMEEQYNQY--QVNGERLNGRQTLGENIADNGGLKAAYNAYKAWL-- 799
ES F+ T CM QY+ Y + G + G++TLGENIADNGGL+ A+ AY+ W+
Sbjct: 604 STESEEKFKEKTKCMINQYSNYYWKKAGLNVKGKRTLGENIADNGGLREAFRAYRKWIND 663
Query: 800 RKHG-EEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSN 858
R+ G EE LP + TN+QLFF+ +A V C+ PE++ E + HSP +FRV G +SN
Sbjct: 664 RRQGLEEPLLPGITFTNNQLFFLSYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISN 723
Query: 859 SRDFLRHFGCPVGSPMNPG-QLCEVW 883
+F + F CP S MN G C +W
Sbjct: 724 FEEFQKAFNCPPNSTMNRGMDSCRLW 749
>gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens]
Length = 732
Score = 359 bits (922), Expect = 5e-99
Identities = 224/718 (31%), Positives = 355/718 (49%), Gaps = 53/718 (7%)
Query: 186 LLLAALLLGCLVALGVQYH---RDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFS 242
+L A L+LG L+ V ++ C T C+ + L S + V+PC DF+ F+
Sbjct: 48 VLTAILILGLLLCFSVLLFYNFQNCGPRPCETSVCLDLRDHYLASGNTSVAPCTDFFSFA 107
Query: 243 CGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQV 302
CG N N+F L +N+ L+ +LE E+K +FY SC+
Sbjct: 108 CGRAKETN---------NSFQELATKNKNRLRRILEVQNSWHPGSGEEKAFQFYNSCMDT 158
Query: 303 ERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSS 362
IE G PLR +IE++GGW I+G W NF L+ + Y PFF Y+ S
Sbjct: 159 LAIEAAGTGPLRQVIEELGGWRISGKWTSLNFNRTLRLLMSQYGHFPFFRAYLGPHPASP 218
Query: 363 NSNVIQVDQSGLFLPSRDYYLNRTANEK----VLTAYLDYMEELGMLLGGRPTSTREQMQ 418
++ VIQ+DQ P D L + +K + YL Y+ +LG LLGG P+ +E
Sbjct: 219 HTPVIQIDQ-----PEFDVPLKQDQEQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSS 273
Query: 419 QVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSE 478
+ + +L P +QRR + K++ ++I +L+ +AP++DWL L +P+ LS S+
Sbjct: 274 LSISITSRLFQFLRPLEQRRAQGKLFQMVTIDQLKEMAPAIDWLSCLQATFTPMSLSPSQ 333
Query: 479 PVVVYGMDYLQQVSELINR---TEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLY 535
+VV+ ++YL+ +S+L+ + L +++I LV + +LD +F+ A+ KL + L
Sbjct: 334 SLVVHDVEYLKNMSQLVEEMLLKQRDFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLR 393
Query: 536 GTKKS----CVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEA 591
+ PRW C+ T L +LFV+ F ++ A + + IR A
Sbjct: 394 ELTEQPPMPARPRWMKCVEETGTFFEPTLAALFVREAFGPSTRSAAMKLFTAIRDALITR 453
Query: 592 LGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLY 651
L L WM+E+T+ A++K + +G ++ L+P+ Y+ ++ SF Q++L+
Sbjct: 454 LRNLPWMNEETQNMAQDKVAQLQVEMGASEWALKPELARQEYNDIQLG-SSFLQSVLSCV 512
Query: 652 NFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNF 711
+ +P + +W ++P VNAYY + + +VFPAG+LQ PF+ +P+A+NF
Sbjct: 513 RSLRARIVQSFLQPHPQHRWKVSPWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNF 572
Query: 712 GGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHT-----ACMEEQYNQYQ 766
G G +M HEL H F L P A NH C++ Y +
Sbjct: 573 GAAGSIMAHELLHIFYQL---------LLP----GGCLACDNHALQEAHLCLKRHYAAFP 619
Query: 767 V-NGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQ 825
+ + N T EN AD GGL A AY L +H E LP++ L+ Q+FF +AQ
Sbjct: 620 LPSRTSFNDSLTFLENAADVGGLAIALQAYSKRLLRHHGETVLPSLDLSPQQIFFRSYAQ 679
Query: 826 VWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 883
V C +P+ SH D HSP RV G LS++ F R+F C G+ +NP C++W
Sbjct: 680 VMCRKPSPQDSH-----DTHSPPHLRVHGPLSSTPAFARYFRCARGALLNPSSRCQLW 732
>gi|153945707 endothelin converting enzyme 2 isoform C [Homo
sapiens]
Length = 255
Score = 332 bits (852), Expect = 7e-91
Identities = 161/161 (100%), Positives = 161/161 (100%)
Query: 1 MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED 60
MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED
Sbjct: 1 MASPGAGRAPPELPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPED 60
Query: 61 RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP 120
RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP
Sbjct: 61 RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVVAAMQARHAHVPQLRWETMDVRKLDFP 120
Query: 121 SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEV 161
SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEV
Sbjct: 121 SASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEV 161
>gi|42542403 CGI-01 protein isoform 1 [Homo sapiens]
Length = 699
Score = 108 bits (271), Expect = 2e-23
Identities = 60/171 (35%), Positives = 104/171 (60%), Gaps = 10/171 (5%)
Query: 13 LPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSAL 72
LP+ + + V+YW++ +Q A ++W+G + +L ++P +++LV+GCGNS L
Sbjct: 4 LPKSSREFGSVDYWEKFFQQRGKKA-FEWYGTYLELCGVLHKYIKPREKVLVIGCGNSEL 62
Query: 73 SYELFLGGFPNVTSVDYSSVVVAAMQARHA-HVPQLRWETMDVRKLDFPSASFDVVLEKG 131
S +L+ G+ ++ ++D S VV+ M+ +A PQ+ + MD+ +++FP ASF VVL+KG
Sbjct: 63 SEQLYDVGYRDIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQMEFPDASFQVVLDKG 122
Query: 132 TLDALLAGERDPWTVSSEGVHTVDQVLSEVG--FQKGTRQLLGSRTQLELV 180
TLDA+L E + + + VD++L+EVG Q G R L S Q ++
Sbjct: 123 TLDAVLTDEEE------KTLQQVDRMLAEVGRVLQVGGRYLCISLAQAHIL 167
>gi|55956895 CGI-01 protein isoform 3 [Homo sapiens]
Length = 543
Score = 107 bits (267), Expect = 5e-23
Identities = 70/234 (29%), Positives = 125/234 (53%), Gaps = 15/234 (6%)
Query: 13 LPERNCGYREVEYWDQRYQGAADSAPYDWFGDFSSFRALLEPELRPEDRILVLGCGNSAL 72
LP+ + + V+YW++ +Q A ++W+G + +L ++P +++LV+GCGNS L
Sbjct: 4 LPKSSREFGSVDYWEKFFQQRGKKA-FEWYGTYLELCGVLHKYIKPREKVLVIGCGNSEL 62
Query: 73 SYELFLGGFPNVTSVDYSSVVVAAMQARHA-HVPQLRWETMDVRKLDFPSASFDVVLEKG 131
S +L+ G+ ++ ++D S VV+ M+ +A PQ+ + MD+ +++FP ASF VVL+KG
Sbjct: 63 SEQLYDVGYRDIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQMEFPDASFQVVLDKG 122
Query: 132 TLDALLAGERDPWTVSSEGVHTVDQVLSEVGFQKGTRQLLGSRTQLELVLAGASLLLAAL 191
TLDA+L E + + + VD++L+EVG R L G T+ + LAA
Sbjct: 123 TLDAVLTDEEE------KTLQQVDRMLAEVG-----RVLQGRETEWLFGMDEGRKQLAA- 170
Query: 192 LLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGG 245
G + V HR + + + ++ +++E G+ + S GG
Sbjct: 171 SAGFRRLITVALHRGQQYES-MDHIQAELSARVMELAPAGMPTQQQVPFLSVGG 223
>gi|42542405 CGI-01 protein isoform 2 [Homo sapiens]
Length = 613
Score = 53.9 bits (128), Expect = 6e-07
Identities = 32/78 (41%), Positives = 48/78 (61%), Gaps = 8/78 (10%)
Query: 105 PQLRWETMDVRKLDFPSASFDVVLEKGTLDALLAGERDPWTVSSEGVHTVDQVLSEVG-- 162
PQ+ + MD+ +++FP ASF VVL+KGTLDA+L E + + + VD++L+EVG
Sbjct: 10 PQMSFLKMDMTQMEFPDASFQVVLDKGTLDAVLTDEEE------KTLQQVDRMLAEVGRV 63
Query: 163 FQKGTRQLLGSRTQLELV 180
Q G R L S Q ++
Sbjct: 64 LQVGGRYLCISLAQAHIL 81
>gi|58219056 methyltransferase like 10 [Homo sapiens]
Length = 291
Score = 48.1 bits (113), Expect = 4e-05
Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 13/152 (8%)
Query: 24 EYWD-------QRYQGAADSAPYDWFGDFSSFRAL--LEPELRPEDR-ILVLGCGNSALS 73
E+WD Q ++ D+ WFG+ S R + ++ P D +L +G GN
Sbjct: 36 EHWDAVYERELQTFREYGDTGEI-WFGEESMNRLIRWMQKHKIPLDASVLDIGTGNGVFL 94
Query: 74 YELFLGGFPNVTSVDY--SSVVVAAMQARHAHVPQLRWETMDVRKLDFPSASFDVVLEKG 131
EL GF N+T +DY S++ ++ + ++ + D L + F + ++KG
Sbjct: 95 VELAKFGFSNITGIDYSPSAIQLSGSIIEKEGLSNIKLKVEDFLNLSTQLSGFHICIDKG 154
Query: 132 TLDALLAGERDPWTVSSEGVHTVDQVLSEVGF 163
T DA+ + + V ++ +VL GF
Sbjct: 155 TFDAISLNPDNAIEKRKQYVKSLSRVLKVKGF 186
>gi|112734863 methyltransferase like 12 [Homo sapiens]
Length = 240
Score = 42.4 bits (98), Expect = 0.002
Identities = 42/137 (30%), Positives = 62/137 (45%), Gaps = 23/137 (16%)
Query: 26 WDQRY-QGAADSAP-YDWFGDFSSFRALLEPELRPED-----RILVLGCGNSALSYELFL 78
WD+ + Q + P +DWF + + LL P L+ R+L +GCG S+L L+
Sbjct: 36 WDRLHAQPRLGTVPTFDWFFGYDEVQGLLLPLLQEAQAASPLRVLDVGCGTSSLCTGLYT 95
Query: 79 GG-FP-NVTSVDYSSVVVAAMQARHAHVP------------QLRWETMDVRKLDF--PSA 122
P +V VD+S V VA M + P L + D + L S
Sbjct: 96 KSPHPVDVLGVDFSPVAVAHMNSLLEGGPGQTPLCPGHPASSLHFMHADAQNLGAVASSG 155
Query: 123 SFDVVLEKGTLDALLAG 139
SF ++L+KGT DA+ G
Sbjct: 156 SFQLLLDKGTWDAVARG 172
>gi|124487387 ring finger protein 207 [Homo sapiens]
Length = 634
Score = 32.7 bits (73), Expect = 1.5
Identities = 23/73 (31%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 581 ISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIG-FPDFILEPKE--LDDVYDGYE 637
+ ++TA EA+ L M E+ R +A E+ DAI+ + G D + E K L V YE
Sbjct: 211 VKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYE 270
Query: 638 ISEDSFFQNMLNL 650
+ +F + + +L
Sbjct: 271 EKDKAFKEQLSHL 283
>gi|239753431 PREDICTED: similar to endothelin converting
enzyme-like 1 [Homo sapiens]
Length = 97
Score = 32.0 bits (71), Expect = 2.6
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 500 PSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFA 559
P +L+NYL+W++V + L F KL + + G+ K + + + G A
Sbjct: 13 PRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGK-LQELARVSLGQANHHYGMA 71
Query: 560 LGSLFV 565
L +LFV
Sbjct: 72 LRALFV 77
>gi|239747995 PREDICTED: hypothetical protein XP_002346505 [Homo
sapiens]
Length = 97
Score = 32.0 bits (71), Expect = 2.6
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 500 PSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFA 559
P +L+NYL+W++V + L F KL + + G+ K + + + G A
Sbjct: 13 PRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGK-LQELARVSLGQANHHYGMA 71
Query: 560 LGSLFV 565
L +LFV
Sbjct: 72 LRALFV 77
>gi|239741893 PREDICTED: hypothetical protein XP_002342317 [Homo
sapiens]
Length = 97
Score = 32.0 bits (71), Expect = 2.6
Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 500 PSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFA 559
P +L+NYL+W++V + L F KL + + G+ K + + + G A
Sbjct: 13 PRVLHNYLVWDVVVVLSEHLFLPFHEVLHKLAQEMEGSGK-LQELARVSLGQANHHYGMA 71
Query: 560 LGSLFV 565
L +LFV
Sbjct: 72 LRALFV 77
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo
sapiens]
Length = 703
Score = 31.2 bits (69), Expect = 4.4
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 780 ENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFV 821
+++A+N G YN Y A L + Q+LP L NH L+ +
Sbjct: 27 QSLAENSGTTVVYNPYAA-LSIEQQRQKLPVFKLRNHILYLI 67
>gi|15553097 hypothetical protein MGC9084 [Homo sapiens]
Length = 372
Score = 30.8 bits (68), Expect = 5.8
Identities = 13/34 (38%), Positives = 20/34 (58%)
Query: 61 RILVLGCGNSALSYELFLGGFPNVTSVDYSSVVV 94
++L LGCG+ L F GG + DY+S+V+
Sbjct: 190 KVLDLGCGSGLLGITAFKGGSKEIHFQDYNSMVI 223
>gi|4505697 pendrin [Homo sapiens]
Length = 780
Score = 30.0 bits (66), Expect = 9.9
Identities = 11/20 (55%), Positives = 14/20 (70%)
Query: 1 MASPGAGRAPPELPERNCGY 20
MA+PG PP+LPE +C Y
Sbjct: 1 MAAPGGRSEPPQLPEYSCSY 20
>gi|83641876 serine carboxypeptidase vitellogenic-like [Homo
sapiens]
Length = 476
Score = 30.0 bits (66), Expect = 9.9
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 3/69 (4%)
Query: 588 FEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNM 647
+ E L Q+ +DEK ++ +++ + I ++ + LD + DG S+ S+FQN+
Sbjct: 249 YAEFLYQIGLLDEKQKKYFQKQCHECIEHIRKQNWFEAFEILDKLLDGDLTSDPSYFQNV 308
Query: 648 L---NLYNF 653
N YNF
Sbjct: 309 TGCSNYYNF 317
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,287,661
Number of Sequences: 37866
Number of extensions: 1552217
Number of successful extensions: 3601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3499
Number of HSP's gapped (non-prelim): 35
length of query: 883
length of database: 18,247,518
effective HSP length: 111
effective length of query: 772
effective length of database: 14,044,392
effective search space: 10842270624
effective search space used: 10842270624
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.