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Search of human proteins with 153281158
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
(625 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153281158 dual specificity phosphatase 8 [Homo sapiens] 1268 0.0
gi|38372911 dual specificity phosphatase 16 [Homo sapiens] 495 e-140
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens] 181 2e-45
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 168 2e-41
gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens] 168 2e-41
gi|4758204 dual specificity phosphatase 1 [Homo sapiens] 163 4e-40
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 163 4e-40
gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens] 162 7e-40
gi|4758206 dual specificity phosphatase 2 [Homo sapiens] 153 5e-37
gi|62865890 dual specificity phosphatase 5 [Homo sapiens] 134 3e-31
gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens] 129 8e-30
gi|21536333 dual specificity phosphatase 10 isoform b [Homo sapi... 99 9e-21
gi|21536331 dual specificity phosphatase 10 isoform b [Homo sapi... 99 9e-21
gi|239582767 slingshot homolog 3 [Homo sapiens] 97 3e-20
gi|239047414 slingshot 1 isoform 1 [Homo sapiens] 93 6e-19
gi|239047498 slingshot 1 isoform 3 [Homo sapiens] 93 6e-19
gi|239047441 slingshot 1 isoform 2 [Homo sapiens] 93 6e-19
gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo ... 89 9e-18
gi|194733759 serine/threonine/tyrosine interacting protein [Homo... 89 9e-18
gi|21687043 serine/threonine/tyrosine interacting protein [Homo ... 89 9e-18
gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens] 89 1e-17
gi|75750526 dual specificity phosphatase 28 [Homo sapiens] 89 2e-17
gi|37674210 slingshot 2 [Homo sapiens] 89 2e-17
gi|9910432 dual specificity phosphatase 22 [Homo sapiens] 88 3e-17
gi|51093845 dual specificity phosphatase 18 [Homo sapiens] 87 4e-17
gi|5902002 dual specificity phosphatase 14 [Homo sapiens] 86 1e-16
gi|29826315 dual specificity phosphatase 15 isoform a [Homo sapi... 85 2e-16
gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo sapi... 81 3e-15
gi|225703077 dual specificity phosphatase 21 [Homo sapiens] 80 4e-15
gi|13128968 dual specificity phosphatase 26 [Homo sapiens] 70 4e-12
>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
Length = 625
Score = 1268 bits (3280), Expect = 0.0
Identities = 625/625 (100%), Positives = 625/625 (100%)
Query: 1 MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQ 60
MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQ
Sbjct: 1 MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQ 60
Query: 61 QGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVA 120
QGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVA
Sbjct: 61 QGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVA 120
Query: 121 ILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKD 180
ILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKD
Sbjct: 121 ILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKD 180
Query: 181 LMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSC 240
LMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSC
Sbjct: 181 LMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSC 240
Query: 241 QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 300
QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL
Sbjct: 241 QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 300
Query: 301 KLLAALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPA 360
KLLAALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPA
Sbjct: 301 KLLAALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATGNAAAREGGLSAGGEPPA 360
Query: 361 PPTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPGEAP 420
PPTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPGEAP
Sbjct: 361 PPTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPGEAP 420
Query: 421 KLCKLDSPSGAALGLSSPSPDSPDAAPEARPRPRRRPRPPAGSPARSPAHSLGLNFGDAA 480
KLCKLDSPSGAALGLSSPSPDSPDAAPEARPRPRRRPRPPAGSPARSPAHSLGLNFGDAA
Sbjct: 421 KLCKLDSPSGAALGLSSPSPDSPDAAPEARPRPRRRPRPPAGSPARSPAHSLGLNFGDAA 480
Query: 481 RQTPRHGLSALSAPGLPGPGQPAGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFA 540
RQTPRHGLSALSAPGLPGPGQPAGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFA
Sbjct: 481 RQTPRHGLSALSAPGLPGPGQPAGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFA 540
Query: 541 PFGRAGAPGPGGGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEGMVEGR 600
PFGRAGAPGPGGGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEGMVEGR
Sbjct: 541 PFGRAGAPGPGGGSDLRRREAARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEGMVEGR 600
Query: 601 ARGEELAALGKQASFSGSVEVIEVS 625
ARGEELAALGKQASFSGSVEVIEVS
Sbjct: 601 ARGEELAALGKQASFSGSVEVIEVS 625
>gi|38372911 dual specificity phosphatase 16 [Homo sapiens]
Length = 665
Score = 495 bits (1275), Expect = e-140
Identities = 305/665 (45%), Positives = 389/665 (58%), Gaps = 65/665 (9%)
Query: 14 KKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPA 73
++L +LL G L+IDSR FVEYN+ H+L ++NI CSKL+KRRLQQ KV I ELIQ +
Sbjct: 13 ERLVALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQDKVLITELIQHS 72
Query: 74 ARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCF 133
A+ +V+ Q VVVYDQS++D + L++D FL++LL KL+ F+SV +L GGFA FS CF
Sbjct: 73 AKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHLLAGGFAEFSRCF 132
Query: 134 PGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNA 193
PGLCEGK + L+P +SQPCLPV ++G TRILP+LYLG Q+DVLNK+LM QNGI YVLNA
Sbjct: 133 PGLCEGK-STLVPTCISQPCLPVANIGPTRILPNLYLGCQRDVLNKELMQQNGIGYVLNA 191
Query: 194 SNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRS 253
SN+CPKPDFI ES F+RVP+ND++CEK+LPWLDKS++FI+KAK S+ V+VHCLAGISRS
Sbjct: 192 SNTCPKPDFIPESHFLRVPVNDSFCEKILPWLDKSVDFIEKAKASNGCVLVHCLAGISRS 251
Query: 254 ATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQGDPGT- 312
ATIAIAYIMK M MS D+AYRFVK++RP+ISPNFNFLGQLL+YE+ +K G
Sbjct: 252 ATIAIAYIMKRMDMSLDEAYRFVKEKRPTISPNFNFLGQLLDYEKKIKNQTGASGPKSKL 311
Query: 313 ----PSGTPEPPPSPAAGAPLPRLP--PPTSESAATGNAAARE-GGLSAGGEPPAPPTPP 365
EP P+ + G P PP ++SA + A R S P P+
Sbjct: 312 KLLHLEKPNEPVPAVSEGGQKSETPLSPPCADSATSEAAGQRPVHPASVPSVPSVQPSLL 371
Query: 366 ATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSA----------------------YA 403
S L Q L GLHLS+DRL+D+N+LKRSFSLDIKS Y
Sbjct: 372 EDSPLVQALSGLHLSADRLEDSNKLKRSFSLDIKSVSYSASMAASLHGFSSSEDALEYYK 431
Query: 404 PSRRPDGPGPPDPGEAPKLCKLDSPSGAALGLSSPSPDSPDAA-----PEARPRPRRRPR 458
PS DG KLC+ + SPD +A+ ARP + R
Sbjct: 432 PSTTLDGTN--------KLCQFSPVQELSEQTPETSPDKEEASIPKKLQTARPSDSQSKR 483
Query: 459 ------PPAGSPAR---SPAHSLGLNFGDAARQTPRHGLSALSAPGLPGPGQPAGPGAWA 509
+G+ R SP H G + D + GLS G G W
Sbjct: 484 LHSVRTSSSGTAQRSLLSPLHRSG-SVEDNYHTSFLFGLSTSQQHLTKSAG--LGLKGWH 540
Query: 510 PPLDSP--GTPSPDGPWCFSPE-------GAQGAGGVLFAPFGRAGAPGPGGGSDLRRRE 560
+ +P TPS W F+ E A G ++ + + P G RR
Sbjct: 541 SDILAPQTSTPSLTSSWYFATESSHFYSASAIYGGSASYSAYSCSQLPTCGDQVYSVRRR 600
Query: 561 AARAEPRDARTGWPEEPAPETQFKRRSCQMEFEEGMVEGRARGEELAALGKQASFSGSVE 620
++ D+R W EE E QFKRRSCQMEF E ++ EEL +G Q+SFSGS+E
Sbjct: 601 QKPSDRADSRRSWHEESPFEKQFKRRSCQMEFGESIMSENRSREELGKVGSQSSFSGSME 660
Query: 621 VIEVS 625
+IEVS
Sbjct: 661 IIEVS 665
>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
Length = 482
Score = 181 bits (459), Expect = 2e-45
Identities = 106/292 (36%), Positives = 163/292 (55%), Gaps = 17/292 (5%)
Query: 26 GPLVIDSRSFVEYNSWHVLSSVNI-CCSKLVKRRLQQGKVTIAELIQ-PAARSQVEATEP 83
GP++ID R F+EYN H+ +V+I C K+ +RRLQQGK+T+ +LI + +
Sbjct: 171 GPVIIDCRPFMEYNKSHIQGAVHINCADKISRRRLQQGKITVLDLISCREGKDSFKRIFS 230
Query: 84 QDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCE----- 138
++++VYD++T + S + L I+L L +L GG ++F LC+
Sbjct: 231 KEIIVYDENTNEPSRVMPSQPLHIVLESLKREGKEPLVLKGGLSSFKQNHENLCDNSLQL 290
Query: 139 ------GKPAALLPMSLSQPCLPVPSVG---LTRILPHLYLGSQKDVLNKDLMTQNGISY 189
G A+ L QP P + LT ILP L+LG+++D + D M + I Y
Sbjct: 291 QECREVGGGASAASSLLPQPIPTTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGY 350
Query: 190 VLNASNSCPKPDFICES-RFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLA 248
V+N + P + + R+P D+ + L + +++ EFI++A +++HC A
Sbjct: 351 VINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQA 410
Query: 249 GISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 300
G+SRSATI IAY+MK M+ DAY+FVK +RP ISPN NF+GQLLE+E L
Sbjct: 411 GVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 462
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 168 bits (425), Expect = 2e-41
Identities = 114/330 (34%), Positives = 175/330 (53%), Gaps = 57/330 (17%)
Query: 21 RGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQVEA 80
RGG L++D R + S H+ +++N+ L+ RRL++G + I +I A + A
Sbjct: 67 RGG-ASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFA 125
Query: 81 T--EPQDVVVYDQSTRD--ASVLAADSFLSILLSKL--DGCFDSVAILTGGFATFSSCFP 134
T + V++YD++T + A S L +LL KL DGC L GGF F + +
Sbjct: 126 TRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGC--QAYYLQGGFNKFQTEYS 183
Query: 135 GLCE-----------GKPAALL------------------------------PMSLSQPC 153
CE P ++L P+ SQP
Sbjct: 184 EHCETNVDSSSSPSSSPPTSVLGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQPA 243
Query: 154 LPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKP-DFICESRFMRVP 212
PV +ILP+LYLG KD N D++ + GI Y+LN + + P + E + ++P
Sbjct: 244 FPV------QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIP 297
Query: 213 INDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDA 272
I+D++ + L + ++I FID+A+ C V+VHCLAGISRS T+ +AY+M+ M +S +DA
Sbjct: 298 ISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDA 357
Query: 273 YRFVKDRRPSISPNFNFLGQLLEYERSLKL 302
Y FVK ++ +ISPNFNF+GQLL++ER+L L
Sbjct: 358 YDFVKRKKSNISPNFNFMGQLLDFERTLGL 387
>gi|4503417 dual specificity phosphatase 4 isoform 1 [Homo sapiens]
Length = 394
Score = 168 bits (425), Expect = 2e-41
Identities = 108/323 (33%), Positives = 175/323 (54%), Gaps = 28/323 (8%)
Query: 25 GGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELI--QPAARSQVEATE 82
G L++D R F+ +++ ++L SVN+ C+ +V+RR + G V++ +++ + R+++ +
Sbjct: 43 GKCLLLDCRPFLAHSAGYILGSVNVRCNTIVRRRAK-GSVSLEQILPAEEEVRARLRSGL 101
Query: 83 PQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFD--SVAILTGGFATFSSCFPGLCEGK 140
V+VYD+ + A L DS +S+++ L + + +L GG+ FSS +P C
Sbjct: 102 YSAVIVYDERSPRAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKT 161
Query: 141 -----------PAALLPMSLSQPCLPVP---SVGLTRILPHLYLGSQKDVLNKDLMTQNG 186
P+A P+ L P G ILP LYLGS +D++ G
Sbjct: 162 KALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALG 221
Query: 187 ISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHC 246
I+ +LN S+ CP F ++ +P+ DN+ + W ++IE+ID K +V+VHC
Sbjct: 222 ITALLNVSSDCPN-HFEGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHC 280
Query: 247 LAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAAL 306
AGISRSATI +AY+M + ++A+ FVK RR ISPNF+F+GQLL++E S L +
Sbjct: 281 QAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFE-SQVLATSC 339
Query: 307 QGDPGTPSG-------TPEPPPS 322
+ +PSG TP P S
Sbjct: 340 AAEAASPSGPLRERGKTPATPTS 362
>gi|4758204 dual specificity phosphatase 1 [Homo sapiens]
Length = 367
Score = 163 bits (413), Expect = 4e-40
Identities = 112/321 (34%), Positives = 171/321 (53%), Gaps = 20/321 (6%)
Query: 11 MDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELI 70
+DA L +LL L++D RSF +N+ H+ SVN+ S +V+RR + G + + ++
Sbjct: 8 LDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAK-GAMGLEHIV 66
Query: 71 QPAA-RSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKL--DGCFDSVAILTGGFA 127
A R ++ A VV+ D+ + D L++ L + V L GG+
Sbjct: 67 PNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYE 126
Query: 128 TFSSCFPGLC--EGKPAAL-LPMSLSQP------CLPVPSV-----GLTRILPHLYLGSQ 173
FS+ P LC + P L LP+S S P C + G ILP LYLGS
Sbjct: 127 AFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSA 186
Query: 174 KDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFID 233
KD++ GI+ ++N S +CP F ++ +P+ DN+ + W +++I+FID
Sbjct: 187 YHASRKDMLDALGITALINVSANCPN-HFEGHYQYKSIPVEDNHKADISSWFNEAIDFID 245
Query: 234 KAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQL 293
K + +V VHC AGISRSATI +AY+M+T + D+A+ FVK RR ISPNF+F+GQL
Sbjct: 246 SIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQL 305
Query: 294 LEYERSLKLLAALQGDPGTPS 314
L++E S L + G+P+
Sbjct: 306 LQFE-SQVLAPHCSAEAGSPA 325
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 163 bits (413), Expect = 4e-40
Identities = 113/352 (32%), Positives = 176/352 (50%), Gaps = 66/352 (18%)
Query: 28 LVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQVEATEPQDVV 87
L++D RS Y S + ++++ L+ RRL++G +++ L+ ++ P V+
Sbjct: 23 LLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPP---LQPPPPAPVL 79
Query: 88 VYDQ---------STRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCE 138
+YDQ + +A A+S L LL KL L GGF+ F + P LCE
Sbjct: 80 LYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCE 139
Query: 139 GKPAALLPMSLSQPCLPVPSVGL------------------------------------- 161
A S++ PVP VGL
Sbjct: 140 TSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPVGL 199
Query: 162 -----TRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPK-----PDFICESRFMRV 211
+ILP+LYLGS +D N + + + GI Y+LN + + P DF + ++
Sbjct: 200 RASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDF----HYKQI 255
Query: 212 PINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDD 271
PI+D++ + L + ++IEFID+A +C V+VHCLAG+SRS T+ +AY+M+ + +S +D
Sbjct: 256 PISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLND 315
Query: 272 AYRFVKDRRPSISPNFNFLGQLLEYERSLKL---LAALQGDPGTPSGTPEPP 320
AY VK ++ +ISPNFNF+GQLL++ERSL+L + QG G S PP
Sbjct: 316 AYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPP 367
>gi|42764683 dual specificity phosphatase 6 isoform a [Homo sapiens]
Length = 381
Score = 162 bits (411), Expect = 7e-40
Identities = 109/323 (33%), Positives = 167/323 (51%), Gaps = 56/323 (17%)
Query: 28 LVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQ--VEATEPQD 85
L++D R Y S H+ S++N+ ++ RRLQ+G + + L
Sbjct: 35 LLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDT 94
Query: 86 VVVYDQSTRDASV-LAADSFLSILLSKL--DGCFDSVAILTGGFATFSSCFPGLCE---- 138
VV+YD+S+ D + +S L +LL KL +GC L GGF+ F + F CE
Sbjct: 95 VVLYDESSSDWNENTGGESVLGLLLKKLKDEGC--RAFYLEGGFSKFQAEFSLHCETNLD 152
Query: 139 ------GKPAALL--------------------------------PMSLSQPCLPVPSVG 160
P +L P+S SQP PV
Sbjct: 153 GSCSSSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPV---- 208
Query: 161 LTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKP-DFICESRFMRVPINDNYCE 219
ILP LYLG KD N D++ + GI Y+LN + + P + E ++ ++PI+D++ +
Sbjct: 209 --EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQ 266
Query: 220 KLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDR 279
L + ++I FID+A+ +C V+VHCLAGISRS T+ +AY+M+ + +S +DAY VK +
Sbjct: 267 NLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMK 326
Query: 280 RPSISPNFNFLGQLLEYERSLKL 302
+ +ISPNFNF+GQLL++ER+L L
Sbjct: 327 KSNISPNFNFMGQLLDFERTLGL 349
>gi|4758206 dual specificity phosphatase 2 [Homo sapiens]
Length = 314
Score = 153 bits (386), Expect = 5e-37
Identities = 103/282 (36%), Positives = 150/282 (53%), Gaps = 13/282 (4%)
Query: 28 LVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQP--AARSQVEATEPQD 85
L++D R F+ + HV ++ + + L++RR + + + P A R+++ E
Sbjct: 28 LLLDCRPFLAFCRRHVRAARPVPWNALLRRRARGPPAAVLACLLPDRALRTRLVRGELAR 87
Query: 86 VVVYDQSTRDASVLAADS----FLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKP 141
VV D+ + + L DS L+ LL + +V L GGF F C P LC P
Sbjct: 88 AVVLDEGSASVAELRPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGFQGCCPDLCSEAP 147
Query: 142 AALLP-----MSLSQPCLPV-PSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASN 195
A LP S S PV G ILP+L+LGS + + GI+ VLN S
Sbjct: 148 APALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSA 207
Query: 196 SCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSAT 255
SCP F R+ +P+ DN ++ W ++I FID K S +V+VHC AGISRSAT
Sbjct: 208 SCPN-HFEGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSAT 266
Query: 256 IAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYE 297
I +AY+M++ + D+A+ FVK RR ISPNF+F+GQLL++E
Sbjct: 267 ICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFE 308
>gi|62865890 dual specificity phosphatase 5 [Homo sapiens]
Length = 384
Score = 134 bits (337), Expect = 3e-31
Identities = 106/344 (30%), Positives = 169/344 (49%), Gaps = 36/344 (10%)
Query: 11 MDAKKLASLLRGGPGGP-LVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAEL 69
+D ++L +LR +V+D R ++ + + +V S+N+ + +V RR + G V+ +
Sbjct: 6 LDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLNSVVLRRARGGAVSARYV 65
Query: 70 I-QPAARS---QVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDS---VAIL 122
+ AAR+ Q VVV DQ +R L +S ++L+ L C + V L
Sbjct: 66 LPDEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARVVLTSLLACLPAGPRVYFL 125
Query: 123 TGGFATFSSCFPGLC-EGKPAALLPMS-----LSQPCLPVPSV---------GLTRILPH 167
GG+ TF S +P C + KP + + +SQ PV +V G ILP
Sbjct: 126 KGGYETFYSEYPECCVDVKPISQEKIESERALISQCGKPVVNVSYRPAYDQGGPVEILPF 185
Query: 168 LYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESR--FMRVPINDNYCEKLLPWL 225
LYLGS + + I+ +LN S + C + + +P+ D++ +
Sbjct: 186 LYLGSAYHASKCEFLANLHITALLNVSRRTSEA---CATHLHYKWIPVEDSHTADISSHF 242
Query: 226 DKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISP 285
++I+FID + +V+VHC AGISRS TI +AY+MKT +A+ ++K RR +SP
Sbjct: 243 QEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSMVSP 302
Query: 286 NFNFLGQLLEYERSLKLLAALQGDPGTPSGTPEPPPSPAAGAPL 329
NF F+GQLL+YE + P TP+ P AAG+ L
Sbjct: 303 NFGFMGQLLQYESEIL--------PSTPNPQPPSCQGEAAGSSL 338
>gi|16950652 dual specificity phosphatase 4 isoform 2 [Homo sapiens]
Length = 303
Score = 129 bits (324), Expect = 8e-30
Identities = 81/220 (36%), Positives = 115/220 (52%), Gaps = 23/220 (10%)
Query: 124 GGFATFSSCFPGLCEGK-----------PAALLPMSLSQPCLPVP---SVGLTRILPHLY 169
GG+ FSS +P C P+A P+ L P G ILP LY
Sbjct: 54 GGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLY 113
Query: 170 LGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSI 229
LGS +D++ GI+ +LN S+ CP F ++ +P+ DN+ + W ++I
Sbjct: 114 LGSAYHAARRDMLDALGITALLNVSSDCPN-HFEGHYQYKCIPVEDNHKADISSWFMEAI 172
Query: 230 EFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNF 289
E+ID K +V+VHC AGISRSATI +AY+M + ++A+ FVK RR ISPNF+F
Sbjct: 173 EYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSF 232
Query: 290 LGQLLEYERSLKLLAALQGDPGTPSG-------TPEPPPS 322
+GQLL++E S L + + +PSG TP P S
Sbjct: 233 MGQLLQFE-SQVLATSCAAEAASPSGPLRERGKTPATPTS 271
>gi|21536333 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 99.4 bits (246), Expect = 9e-21
Identities = 51/120 (42%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Query: 182 MTQNGISYVLNASNSCPKPDFICES-RFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSC 240
M + I YV+N + P + + R+P D+ + L + +++ EFI++A
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 241 QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 300
+++HC AG+SRSATI IAY+MK M+ DAY+FVK +RP ISPN NF+GQLLE+E L
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|21536331 dual specificity phosphatase 10 isoform b [Homo
sapiens]
Length = 140
Score = 99.4 bits (246), Expect = 9e-21
Identities = 51/120 (42%), Positives = 75/120 (62%), Gaps = 1/120 (0%)
Query: 182 MTQNGISYVLNASNSCPKPDFICES-RFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSC 240
M + I YV+N + P + + R+P D+ + L + +++ EFI++A
Sbjct: 1 MQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGK 60
Query: 241 QVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 300
+++HC AG+SRSATI IAY+MK M+ DAY+FVK +RP ISPN NF+GQLLE+E L
Sbjct: 61 GLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDL 120
>gi|239582767 slingshot homolog 3 [Homo sapiens]
Length = 659
Score = 97.4 bits (241), Expect = 3e-20
Identities = 68/205 (33%), Positives = 97/205 (47%), Gaps = 11/205 (5%)
Query: 162 TRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFM--RVPINDNYCE 219
+RI PHLYLGS+ + N + + +N ++++LN + D RF V + D
Sbjct: 330 SRIFPHLYLGSEWNAANLEELQRNRVTHILNMAREI---DNFYPERFTYHNVRLWDEESA 386
Query: 220 KLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDR 279
+LLP ++ FI+ A+ V+VHC G+SRSA +AY MK S + A R V++
Sbjct: 387 QLLPHWKETHRFIEAARAQGTHVLVHCKMGVSRSAATVLAYAMKQYECSLEQALRHVQEL 446
Query: 280 RPSISPNFNFLGQLLEYERSLKLLAALQG---DPGTPSGTPEPPPSPAAGAPLPRLPPPT 336
RP PN FL QL Y+ L A+ Q + +PE P+P P P L PP
Sbjct: 447 RPIARPNPGFLRQLQIYQGI--LTASRQSHVWEQKVGGVSPEEHPAPEVSTPFPPL-PPE 503
Query: 337 SESAATGNAAAREGGLSAGGEPPAP 361
E E +A E P P
Sbjct: 504 PEGGGEEKVVGMEESQAAPKEEPGP 528
>gi|239047414 slingshot 1 isoform 1 [Homo sapiens]
Length = 1049
Score = 93.2 bits (230), Expect = 6e-19
Identities = 67/202 (33%), Positives = 93/202 (46%), Gaps = 9/202 (4%)
Query: 164 ILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLP 223
I HLYLGS+ + N + + +G+ Y+LN + F + + + D LL
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDN-FFPGLFAYHNIRVYDEETTDLLA 370
Query: 224 WLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSI 283
+++ FI+KAK + + +VHC G+SRSA+ IAY MK G + AY +VK +R
Sbjct: 371 HWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSIT 430
Query: 284 SPNFNFLGQLLEYERSLKLLAALQGD---PGTPSGTPEPPPSPAA-GAPLPRLPPPTSES 339
PN F+ QL EYE L T S +P PA G LP P T ES
Sbjct: 431 RPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTPES 490
Query: 340 AATGNAAAREGGLSAGGEPPAP 361
A + GL PP P
Sbjct: 491 QLPFLDDAAQPGLG----PPLP 508
>gi|239047498 slingshot 1 isoform 3 [Homo sapiens]
Length = 703
Score = 93.2 bits (230), Expect = 6e-19
Identities = 67/202 (33%), Positives = 93/202 (46%), Gaps = 9/202 (4%)
Query: 164 ILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLP 223
I HLYLGS+ + N + + +G+ Y+LN + F + + + D LL
Sbjct: 323 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDN-FFPGLFAYHNIRVYDEETTDLLA 381
Query: 224 WLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSI 283
+++ FI+KAK + + +VHC G+SRSA+ IAY MK G + AY +VK +R
Sbjct: 382 HWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSIT 441
Query: 284 SPNFNFLGQLLEYERSLKLLAALQGD---PGTPSGTPEPPPSPAA-GAPLPRLPPPTSES 339
PN F+ QL EYE L T S +P PA G LP P T ES
Sbjct: 442 RPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTPES 501
Query: 340 AATGNAAAREGGLSAGGEPPAP 361
A + GL PP P
Sbjct: 502 QLPFLDDAAQPGLG----PPLP 519
>gi|239047441 slingshot 1 isoform 2 [Homo sapiens]
Length = 692
Score = 93.2 bits (230), Expect = 6e-19
Identities = 67/202 (33%), Positives = 93/202 (46%), Gaps = 9/202 (4%)
Query: 164 ILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLP 223
I HLYLGS+ + N + + +G+ Y+LN + F + + + D LL
Sbjct: 312 IFDHLYLGSEWNASNLEELQGSGVDYILNVTREIDN-FFPGLFAYHNIRVYDEETTDLLA 370
Query: 224 WLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSI 283
+++ FI+KAK + + +VHC G+SRSA+ IAY MK G + AY +VK +R
Sbjct: 371 HWNEAYHFINKAKRNHSKCLVHCKMGVSRSASTVIAYAMKEFGWPLEKAYNYVKQKRSIT 430
Query: 284 SPNFNFLGQLLEYERSLKLLAALQGD---PGTPSGTPEPPPSPAA-GAPLPRLPPPTSES 339
PN F+ QL EYE L T S +P PA G LP P T ES
Sbjct: 431 RPNAGFMRQLSEYEGILDASKQRHNKLWRQQTDSSLQQPVDDPAGPGDFLPETPDGTPES 490
Query: 340 AATGNAAAREGGLSAGGEPPAP 361
A + GL PP P
Sbjct: 491 QLPFLDDAAQPGLG----PPLP 508
>gi|239750646 PREDICTED: hypothetical protein XP_002347464 [Homo
sapiens]
Length = 223
Score = 89.4 bits (220), Expect = 9e-18
Identities = 54/143 (37%), Positives = 83/143 (58%), Gaps = 6/143 (4%)
Query: 161 LTRILPHLYLGSQKDVLNKDL--MTQNGISYVL----NASNSCPKPDFICESRFMRVPIN 214
+ ILP L+LG + L + ++GI++++ N + KP+F R++ + I
Sbjct: 29 MQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIA 88
Query: 215 DNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYR 274
DN E ++ + + EFID + +V+VH AGISRSA IAYIM+T GM DA+
Sbjct: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
Query: 275 FVKDRRPSISPNFNFLGQLLEYE 297
+V++RR I+PN F+ QL EYE
Sbjct: 149 YVQERRFCINPNAGFVHQLQEYE 171
>gi|194733759 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 89.4 bits (220), Expect = 9e-18
Identities = 54/143 (37%), Positives = 83/143 (58%), Gaps = 6/143 (4%)
Query: 161 LTRILPHLYLGSQKDVLNKDL--MTQNGISYVL----NASNSCPKPDFICESRFMRVPIN 214
+ ILP L+LG + L + ++GI++++ N + KP+F R++ + I
Sbjct: 29 MQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIA 88
Query: 215 DNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYR 274
DN E ++ + + EFID + +V+VH AGISRSA IAYIM+T GM DA+
Sbjct: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
Query: 275 FVKDRRPSISPNFNFLGQLLEYE 297
+V++RR I+PN F+ QL EYE
Sbjct: 149 YVQERRFCINPNAGFVHQLQEYE 171
>gi|21687043 serine/threonine/tyrosine interacting protein [Homo
sapiens]
Length = 223
Score = 89.4 bits (220), Expect = 9e-18
Identities = 54/143 (37%), Positives = 83/143 (58%), Gaps = 6/143 (4%)
Query: 161 LTRILPHLYLGSQKDVLNKDL--MTQNGISYVL----NASNSCPKPDFICESRFMRVPIN 214
+ ILP L+LG + L + ++GI++++ N + KP+F R++ + I
Sbjct: 29 MQEILPGLFLGPYSSAMKSKLPVLQKHGITHIICIRQNIEANFIKPNFQQLFRYLVLDIA 88
Query: 215 DNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYR 274
DN E ++ + + EFID + +V+VH AGISRSA IAYIM+T GM DA+
Sbjct: 89 DNPVENIIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFA 148
Query: 275 FVKDRRPSISPNFNFLGQLLEYE 297
+V++RR I+PN F+ QL EYE
Sbjct: 149 YVQERRFCINPNAGFVHQLQEYE 171
>gi|42764687 dual specificity phosphatase 6 isoform b [Homo sapiens]
Length = 235
Score = 89.0 bits (219), Expect = 1e-17
Identities = 39/70 (55%), Positives = 57/70 (81%)
Query: 233 DKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQ 292
D+A+ +C V+VHCLAGISRS T+ +AY+M+ + +S +DAY VK ++ +ISPNFNF+GQ
Sbjct: 134 DEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQ 193
Query: 293 LLEYERSLKL 302
LL++ER+L L
Sbjct: 194 LLDFERTLGL 203
Score = 39.7 bits (91), Expect = 0.008
Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 28 LVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQ--VEATEPQD 85
L++D R Y S H+ S++N+ ++ RRLQ+G + + L
Sbjct: 35 LLMDCRPQELYESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDT 94
Query: 86 VVVYDQSTRDASV-LAADSFLSILLSKL--DGC 115
VV+YD+S+ D + +S L +LL KL +GC
Sbjct: 95 VVLYDESSSDWNENTGGESVLGLLLKKLKDEGC 127
>gi|75750526 dual specificity phosphatase 28 [Homo sapiens]
Length = 176
Score = 88.6 bits (218), Expect = 2e-17
Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 2/164 (1%)
Query: 155 PVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPIN 214
PVP L R+ P L+LGS + ++ + + G++ +N S P P + +RVP+
Sbjct: 14 PVPPP-LVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAE-LRVPVF 71
Query: 215 DNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYR 274
D+ E LL L+ + ++ A + +V+C G SRSA + AY+M+ G+S A++
Sbjct: 72 DDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQ 131
Query: 275 FVKDRRPSISPNFNFLGQLLEYERSLKLLAALQGDPGTPSGTPE 318
VK RP PN F QL +YE +L+ + LQG+P PE
Sbjct: 132 MVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPE 175
>gi|37674210 slingshot 2 [Homo sapiens]
Length = 1423
Score = 88.6 bits (218), Expect = 2e-17
Identities = 48/136 (35%), Positives = 75/136 (55%), Gaps = 1/136 (0%)
Query: 162 TRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKL 221
T+I H++LGS+ + N + + G+ Y+LN + F + + + D L
Sbjct: 309 TQIFEHVFLGSEWNASNLEDLQNRGVRYILNVTREIDN-FFPGVFEYHNIRVYDEEATDL 367
Query: 222 LPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRP 281
L + + + +FI KAK + +VHC G+SRSA+ IAY MK G + D AY +VK+RR
Sbjct: 368 LAYWNDTYKFISKAKKHGSKCLVHCKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRT 427
Query: 282 SISPNFNFLGQLLEYE 297
PN +F+ QL EY+
Sbjct: 428 VTKPNPSFMRQLEEYQ 443
>gi|9910432 dual specificity phosphatase 22 [Homo sapiens]
Length = 184
Score = 87.8 bits (216), Expect = 3e-17
Identities = 47/139 (33%), Positives = 82/139 (58%), Gaps = 2/139 (1%)
Query: 160 GLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCE 219
G+ +ILP LY+G+ KD + + +++N ++++L+ +S +P + +++ +P D+ +
Sbjct: 4 GMNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSA-RP-MLEGVKYLCIPAADSPSQ 61
Query: 220 KLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDR 279
L +SI+FI + +L +VHCLAG+SRS T+ IAYIM +DA V+
Sbjct: 62 NLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAG 121
Query: 280 RPSISPNFNFLGQLLEYER 298
R +PN F QL E+E+
Sbjct: 122 RSCANPNVGFQRQLQEFEK 140
>gi|51093845 dual specificity phosphatase 18 [Homo sapiens]
Length = 188
Score = 87.4 bits (215), Expect = 4e-17
Identities = 51/160 (31%), Positives = 85/160 (53%), Gaps = 5/160 (3%)
Query: 141 PAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKP 200
P+ P+ QP + GL++I LY+ + NK +++ N I+ V+N S
Sbjct: 4 PSCAFPVQFRQPSVS----GLSQITKSLYISNGVAANNKLMLSSNQITMVINVSVEVVNT 59
Query: 201 DFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAY 260
+ + ++M+VP+ D+ +L + D + I ++ + ++HC AG+SRSA + +AY
Sbjct: 60 LYE-DIQYMQVPVADSPNSRLCDFFDPIADHIHSVEMKQGRTLLHCAAGVSRSAALCLAY 118
Query: 261 IMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSL 300
+MK MS DA+ + K RP I PN F QL+ YE L
Sbjct: 119 LMKYHAMSLLDAHTWTKSCRPIIRPNSGFWEQLIHYEFQL 158
>gi|5902002 dual specificity phosphatase 14 [Homo sapiens]
Length = 198
Score = 85.9 bits (211), Expect = 1e-16
Identities = 51/144 (35%), Positives = 76/144 (52%), Gaps = 7/144 (4%)
Query: 160 GLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPK---PDFICESRFMRVPINDN 216
G+ +I L+LG N+ L+ GI+ ++NA+ P P F +++VP+ D
Sbjct: 26 GIAQITSSLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQF----EYVKVPLADM 81
Query: 217 YCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFV 276
+ + D + I +VHC AG+SRSAT+ IAY+MK + +AY +V
Sbjct: 82 PHAPIGLYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWV 141
Query: 277 KDRRPSISPNFNFLGQLLEYERSL 300
K RRP I PN F QL++YER L
Sbjct: 142 KARRPVIRPNVGFWRQLIDYERQL 165
>gi|29826315 dual specificity phosphatase 15 isoform a [Homo
sapiens]
Length = 235
Score = 85.1 bits (209), Expect = 2e-16
Identities = 63/194 (32%), Positives = 98/194 (50%), Gaps = 5/194 (2%)
Query: 160 GLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCE 219
G+T++LP LYLG+ D + D + +N I+++++ S P+P + + ++R+P+ D
Sbjct: 4 GMTKVLPGLYLGNFIDAKDLDQLGRNKITHIISIHES-PQP-LLQDITYLRIPVADTPEV 61
Query: 220 KLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDR 279
+ + I FI +L+ +VHC AGISRS TI AY+M G+ D +K
Sbjct: 62 PIKKHFKECINFIHCCRLNGGNCLVHCFAGISRSTTIVTAYVMTVTGLGWRDVLEAIKAT 121
Query: 280 RPSISPNFNFLGQLLEY--ERSLKLLAALQGDPG-TPSGTPEPPPSPAAGAPLPRLPPPT 336
RP +PN F QL E+ S KL L+ G +P E + R T
Sbjct: 122 RPIANPNPGFRQQLEEFGWASSQKLRRQLEERFGESPFRDEEELRALLPLCKRCRQGSAT 181
Query: 337 SESAATGNAAAREG 350
S S+A ++AA EG
Sbjct: 182 SASSAGPHSAASEG 195
>gi|18254478 dual specificity phosphatase 19 isoform 1 [Homo
sapiens]
Length = 217
Score = 81.3 bits (199), Expect = 3e-15
Identities = 46/134 (34%), Positives = 73/134 (54%), Gaps = 1/134 (0%)
Query: 164 ILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLP 223
I P L LGSQ + D + +N ++++LN + F+ + + + I D +L
Sbjct: 69 IKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENA-FLSDFTYKSISILDLPETNILS 127
Query: 224 WLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSI 283
+ + EFI++AK V+VHC AG+SR+A I I ++M + S A+ VK+ RPSI
Sbjct: 128 YFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSI 187
Query: 284 SPNFNFLGQLLEYE 297
PN F+ QL Y+
Sbjct: 188 CPNSGFMEQLRTYQ 201
>gi|225703077 dual specificity phosphatase 21 [Homo sapiens]
Length = 190
Score = 80.5 bits (197), Expect = 4e-15
Identities = 48/145 (33%), Positives = 80/145 (55%), Gaps = 2/145 (1%)
Query: 157 PSV-GLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPIND 215
PS+ ++I L+L + +K L++ N I+ ++NAS F ++++VP+ D
Sbjct: 17 PSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVNV-FFEGIQYIKVPVTD 75
Query: 216 NYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRF 275
+L + D + I + + ++HC+AG+SRSA++ +AY+MK MS DA+ +
Sbjct: 76 ARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAYLMKYHSMSLLDAHTW 135
Query: 276 VKDRRPSISPNFNFLGQLLEYERSL 300
K RRP I PN F QL+ YE L
Sbjct: 136 TKSRRPIIRPNNGFWEQLINYEFKL 160
>gi|13128968 dual specificity phosphatase 26 [Homo sapiens]
Length = 211
Score = 70.5 bits (171), Expect = 4e-12
Identities = 49/143 (34%), Positives = 78/143 (54%), Gaps = 6/143 (4%)
Query: 164 ILPHLYLGSQKDVLNKDLMTQNGISYVLNASNS----CPKPDFICESRFMRVPINDNYCE 219
+ P LYLG Q N+ + + GI++VLNAS+S P+ R++ V +D+
Sbjct: 65 VWPGLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDSPAF 124
Query: 220 KLLPWLDKSIEFIDKA-KLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKD 278
+ + +FI +A +++VHC G+SRSAT+ +AY+M ++ +A + VKD
Sbjct: 125 DMSIHFQTAADFIHRALSQPGGKILVHCAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKD 184
Query: 279 RRPSISPNFNFLGQLLEYERSLK 301
R I PN FL QLL +R L+
Sbjct: 185 HR-GIIPNRGFLRQLLALDRRLR 206
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,442,408
Number of Sequences: 37866
Number of extensions: 2295170
Number of successful extensions: 32416
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 453
Number of HSP's successfully gapped in prelim test: 1931
Number of HSP's that attempted gapping in prelim test: 14768
Number of HSP's gapped (non-prelim): 11392
length of query: 625
length of database: 18,247,518
effective HSP length: 108
effective length of query: 517
effective length of database: 14,157,990
effective search space: 7319680830
effective search space used: 7319680830
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.