Guide to the Human Genome
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Search of human proteins with 151301204

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|151301204 unc-51-like kinase 4 [Homo sapiens]
         (1275 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|151301204 unc-51-like kinase 4 [Homo sapiens]                     2509   0.0  
gi|217330634 serine/threonine kinase 36 [Homo sapiens]                145   2e-34
gi|150456432 unc-51-like kinase 3 [Homo sapiens]                      132   3e-30
gi|4507831 Unc-51-like kinase 1 [Homo sapiens]                        120   1e-26
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor...   120   1e-26
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo...   120   1e-26
gi|4557511 death-associated protein kinase 3 [Homo sapiens]           120   1e-26
gi|29826329 p21-activated kinase 7 [Homo sapiens]                     117   9e-26
gi|24308191 p21-activated kinase 7 [Homo sapiens]                     117   9e-26
gi|217330559 unc-51-like kinase 2 [Homo sapiens]                      116   1e-25
gi|217330557 unc-51-like kinase 2 [Homo sapiens]                      116   1e-25
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca...   114   5e-25
gi|209364619 pregnancy upregulated non-ubiquitously expressed Ca...   114   5e-25
gi|191252782 p21-activated kinase 6 [Homo sapiens]                    114   8e-25
gi|191252780 p21-activated kinase 6 [Homo sapiens]                    114   8e-25
gi|9910476 p21-activated kinase 6 [Homo sapiens]                      114   8e-25
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s...   112   2e-24
gi|25168263 serum/glucocorticoid regulated kinase 1 isoform 1 [H...   111   4e-24
gi|219521880 serum/glucocorticoid regulated kinase 1 isoform 4 [...   111   4e-24
gi|219521878 serum/glucocorticoid regulated kinase 1 isoform 3 [...   111   4e-24
gi|219521876 serum/glucocorticoid regulated kinase 1 isoform 2 [...   111   4e-24
gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens]           111   5e-24
gi|62422561 p21-activated kinase 4 isoform 2 [Homo sapiens]           111   5e-24
gi|62422563 p21-activated kinase 4 isoform 2 [Homo sapiens]           111   5e-24
gi|62422557 p21-activated kinase 4 isoform 1 [Homo sapiens]           111   5e-24
gi|5031975 p21-activated kinase 4 isoform 1 [Homo sapiens]            111   5e-24
gi|121114283 polo-like kinase 4 [Homo sapiens]                        108   3e-23
gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [H...   108   3e-23
gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [H...   108   3e-23
gi|133908623 protein kinase C, iota [Homo sapiens]                    107   7e-23

>gi|151301204 unc-51-like kinase 4 [Homo sapiens]
          Length = 1275

 Score = 2509 bits (6502), Expect = 0.0
 Identities = 1275/1275 (100%), Positives = 1275/1275 (100%)

Query: 1    MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKRPEITNWVRLTREIKHKNIVT 60
            MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKRPEITNWVRLTREIKHKNIVT
Sbjct: 1    MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKRPEITNWVRLTREIKHKNIVT 60

Query: 61   FHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFC 120
            FHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFC
Sbjct: 61   FHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFC 120

Query: 121  DISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVK 180
            DISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVK
Sbjct: 121  DISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVK 180

Query: 181  GSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPI 240
            GSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPI
Sbjct: 181  GSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPI 240

Query: 241  PKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKAFAGADQESSVEDLSLSR 300
            PKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKAFAGADQESSVEDLSLSR
Sbjct: 241  PKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKAFAGADQESSVEDLSLSR 300

Query: 301  NTMECSGPQDSKELLQNSQSRQAKGHKSGQPLGHSFRLENPTEFRPKSTLEGQLNESMFL 360
            NTMECSGPQDSKELLQNSQSRQAKGHKSGQPLGHSFRLENPTEFRPKSTLEGQLNESMFL
Sbjct: 301  NTMECSGPQDSKELLQNSQSRQAKGHKSGQPLGHSFRLENPTEFRPKSTLEGQLNESMFL 360

Query: 361  LSSRPTPRTSTAVEVSPGEDMTHCSPQKTSPLTKITSGHLSQQDLESQMRELIYTDSDLV 420
            LSSRPTPRTSTAVEVSPGEDMTHCSPQKTSPLTKITSGHLSQQDLESQMRELIYTDSDLV
Sbjct: 361  LSSRPTPRTSTAVEVSPGEDMTHCSPQKTSPLTKITSGHLSQQDLESQMRELIYTDSDLV 420

Query: 421  VTPIIDNPKIMKQPPVKFDAKILHLPTYSVDKLLFLKDQDWNDFLQQVCSQIDSTEKSMG 480
            VTPIIDNPKIMKQPPVKFDAKILHLPTYSVDKLLFLKDQDWNDFLQQVCSQIDSTEKSMG
Sbjct: 421  VTPIIDNPKIMKQPPVKFDAKILHLPTYSVDKLLFLKDQDWNDFLQQVCSQIDSTEKSMG 480

Query: 481  ASRAKLNLLCYLCVVAGHQEVATRLLHSPLFQLLIQHLRIAPNWDIRAKVAHVIGLLASH 540
            ASRAKLNLLCYLCVVAGHQEVATRLLHSPLFQLLIQHLRIAPNWDIRAKVAHVIGLLASH
Sbjct: 481  ASRAKLNLLCYLCVVAGHQEVATRLLHSPLFQLLIQHLRIAPNWDIRAKVAHVIGLLASH 540

Query: 541  TAELQENTPVVEAIVLLTELIRENFRNSKLKQCLLPTLGELIYLVATQEEKKKNPRECWA 600
            TAELQENTPVVEAIVLLTELIRENFRNSKLKQCLLPTLGELIYLVATQEEKKKNPRECWA
Sbjct: 541  TAELQENTPVVEAIVLLTELIRENFRNSKLKQCLLPTLGELIYLVATQEEKKKNPRECWA 600

Query: 601  VPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQSQGFITGEIGPILWYLFRHST 660
            VPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQSQGFITGEIGPILWYLFRHST
Sbjct: 601  VPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQSQGFITGEIGPILWYLFRHST 660

Query: 661  ADSLRITAVSALCRITRHSPTAFQNVIEKVGLNSVINSLASAICKVQQYMLTLFAAMLSC 720
            ADSLRITAVSALCRITRHSPTAFQNVIEKVGLNSVINSLASAICKVQQYMLTLFAAMLSC
Sbjct: 661  ADSLRITAVSALCRITRHSPTAFQNVIEKVGLNSVINSLASAICKVQQYMLTLFAAMLSC 720

Query: 721  GIHLQRLIQEKGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREMLLLSCQARLVMYIE 780
            GIHLQRLIQEKGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREMLLLSCQARLVMYIE
Sbjct: 721  GIHLQRLIQEKGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREMLLLSCQARLVMYIE 780

Query: 781  RDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVK 840
            RDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVK
Sbjct: 781  RDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVK 840

Query: 841  QLKLCLPLMPVVLHLVTSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTAS 900
            QLKLCLPLMPVVLHLVTSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTAS
Sbjct: 841  QLKLCLPLMPVVLHLVTSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTAS 900

Query: 901  EEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVEWRLFSLRLLSETTS 960
            EEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVEWRLFSLRLLSETTS
Sbjct: 901  EEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVEWRLFSLRLLSETTS 960

Query: 961  LLVNQEFGDGKEKASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNP 1020
            LLVNQEFGDGKEKASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNP
Sbjct: 961  LLVNQEFGDGKEKASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNP 1020

Query: 1021 TFTRLVEESKLIPLIFEVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSH 1080
            TFTRLVEESKLIPLIFEVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSH
Sbjct: 1021 TFTRLVEESKLIPLIFEVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSH 1080

Query: 1081 ICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIVRLALQAQKSGSGED 1140
            ICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIVRLALQAQKSGSGED
Sbjct: 1081 ICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIVRLALQAQKSGSGED 1140

Query: 1141 PQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENV 1200
            PQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENV
Sbjct: 1141 PQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENV 1200

Query: 1201 EIFAHLLTSKEDPKEQKLLLRILRRMITSNEKHLESLKNAGSLLRALERLAPGSGSFADS 1260
            EIFAHLLTSKEDPKEQKLLLRILRRMITSNEKHLESLKNAGSLLRALERLAPGSGSFADS
Sbjct: 1201 EIFAHLLTSKEDPKEQKLLLRILRRMITSNEKHLESLKNAGSLLRALERLAPGSGSFADS 1260

Query: 1261 AVAPLALEILQAVGH 1275
            AVAPLALEILQAVGH
Sbjct: 1261 AVAPLALEILQAVGH 1275


>gi|217330634 serine/threonine kinase 36 [Homo sapiens]
          Length = 1315

 Score =  145 bits (367), Expect = 2e-34
 Identities = 95/284 (33%), Positives = 143/284 (50%), Gaps = 36/284 (12%)

Query: 1   MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKRPE-----ITNWVRLTREIKH 55
           ME + + E IG GS   VYKGRRK +   VA+    K  R E     +   + + R ++H
Sbjct: 1   MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRH 60

Query: 56  KNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKL 115
            NIV   + +ET   + +V +   G  L  ++  D  LPED V+     L+S L++LH  
Sbjct: 61  PNIVHMLDSFETDKEVVVVTDYAEG-ELFQILEDDGKLPEDQVQAIAAQLVSALYYLHSH 119

Query: 116 GILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSM 175
            IL  D+ P+ ILL   G +K  +F  A+    N                         +
Sbjct: 120 RILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNT-----------------------MV 156

Query: 176 KSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCED 235
            + +KG+P+Y +PE+V    +  ++DLWS+GC+LYE+  G PPF++ SI +L   IL + 
Sbjct: 157 LTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKD- 215

Query: 236 PLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSF 279
              P+   S+    S  F N L GLL +DP++RL+W  LL H F
Sbjct: 216 ---PVRWPST---ISPCFKNFLQGLLTKDPRQRLSWPDLLYHPF 253


>gi|150456432 unc-51-like kinase 3 [Homo sapiens]
          Length = 472

 Score =  132 bits (331), Expect = 3e-30
 Identities = 94/289 (32%), Positives = 137/289 (47%), Gaps = 44/289 (15%)

Query: 1   MENFILYEEIGRGSKTVVYKG-RRKGTINFVAILCT-----DKCKRPEITNWVRLTREIK 54
           ++ FIL E +G G+   VYK   +K T   VAI C      +K     +   + + + I+
Sbjct: 11  LDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIR 70

Query: 55  HKNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHK 114
           H +IV   ++   S++++L++E C GG L   I     LPE V R F   L S L  LH+
Sbjct: 71  HPHIVQLKDFQWDSDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHE 130

Query: 115 LGILFCDISPRKILLEG--PGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLK 172
             I   D+ P+ ILL       LK ++F  A                        +++  
Sbjct: 131 RNISHLDLKPQNILLSSLEKPHLKLADFGFA------------------------QHMSP 166

Query: 173 KSMKSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKI- 231
              K  ++GSP+Y APE+V    +    DLWS+G +LYE   G+PPF S S SEL EKI 
Sbjct: 167 WDEKHVLRGSPLYMAPEMVCQRQYDARVDLWSMGVILYEALFGQPPFASRSFSELEEKIR 226

Query: 232 ---LCEDPLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQH 277
              + E PL        RP  S D  +LL  LL+RDP +R+++     H
Sbjct: 227 SNRVIELPL--------RPLLSRDCRDLLQRLLERDPSRRISFQDFFAH 267


>gi|4507831 Unc-51-like kinase 1 [Homo sapiens]
          Length = 1050

 Score =  120 bits (300), Expect = 1e-26
 Identities = 81/279 (29%), Positives = 135/279 (48%), Gaps = 32/279 (11%)

Query: 10  IGRGSKTVVYKGRRKGTINF-VAILCTDKCKRPE----ITNWVRLTREIKHKNIVTFHEW 64
           IG G+  VV+KGR +   +  VA+ C +K    +    +   +++ +E+KH+NIV  +++
Sbjct: 22  IGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDF 81

Query: 65  YETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDISP 124
            E +N ++LV+E C GG L   +     L ED +R F   +   +  LH  GI+  D+ P
Sbjct: 82  QEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKP 141

Query: 125 RKILLEGP-GTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSP 183
           + ILL  P G     N    K+       +                +    M + + GSP
Sbjct: 142 QNILLSNPAGRRANPNSIRVKIADFGFARY----------------LQSNMMAATLCGSP 185

Query: 184 VYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDP---LPPI 240
           +Y APEV+    +   +DLWS+G ++Y+  +GK PF + S  +L  ++  E     +P I
Sbjct: 186 MYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDL--RLFYEKNKTLVPTI 243

Query: 241 PKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSF 279
           P+++S P        LL  LLQR+ + R+ +     H F
Sbjct: 244 PRETSAP-----LRQLLLALLQRNHKDRMDFDEFFHHPF 277


>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
           [Homo sapiens]
          Length = 357

 Score =  120 bits (300), Expect = 1e-26
 Identities = 94/327 (28%), Positives = 150/327 (45%), Gaps = 47/327 (14%)

Query: 4   FILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKC----KRPEITNWVRLTREIKHKNIV 59
           F   E +G G+ + V     K T    A+ C  K     K   I N + + R+IKH+NIV
Sbjct: 23  FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIV 82

Query: 60  TFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILF 119
              + YE+ NHL+LV++L +GG L   I +     E         ++  +++LH++GI+ 
Sbjct: 83  ALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVH 142

Query: 120 CDISPRKILL---EGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMK 176
            D+ P  +L    +    +  S+F L+K+EG                        K  + 
Sbjct: 143 RDLKPENLLYYSQDEESKIMISDFGLSKMEG------------------------KGDVM 178

Query: 177 SRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDP 236
           S   G+P Y APEV+    +S + D WS+G + Y +  G PPF+ E+ S+L E+IL  + 
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEY 238

Query: 237 LPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKAFAGADQESSVEDL 296
               P       ++ DFI     L+++DP KR T  +  +H +     AG        D 
Sbjct: 239 EFDSPYWDDISDSAKDFIR---NLMEKDPNKRYTCEQAARHPW----IAG--------DT 283

Query: 297 SLSRNTMECSGPQDSKELLQNSQSRQA 323
           +L++N  E    Q  K   + S+ RQA
Sbjct: 284 ALNKNIHESVSAQIRKNFAK-SKWRQA 309


>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
           2 [Homo sapiens]
          Length = 385

 Score =  120 bits (300), Expect = 1e-26
 Identities = 94/327 (28%), Positives = 150/327 (45%), Gaps = 47/327 (14%)

Query: 4   FILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKC----KRPEITNWVRLTREIKHKNIV 59
           F   E +G G+ + V     K T    A+ C  K     K   I N + + R+IKH+NIV
Sbjct: 23  FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIV 82

Query: 60  TFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILF 119
              + YE+ NHL+LV++L +GG L   I +     E         ++  +++LH++GI+ 
Sbjct: 83  ALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVH 142

Query: 120 CDISPRKILL---EGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMK 176
            D+ P  +L    +    +  S+F L+K+EG                        K  + 
Sbjct: 143 RDLKPENLLYYSQDEESKIMISDFGLSKMEG------------------------KGDVM 178

Query: 177 SRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDP 236
           S   G+P Y APEV+    +S + D WS+G + Y +  G PPF+ E+ S+L E+IL  + 
Sbjct: 179 STACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEY 238

Query: 237 LPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKAFAGADQESSVEDL 296
               P       ++ DFI     L+++DP KR T  +  +H +     AG        D 
Sbjct: 239 EFDSPYWDDISDSAKDFIR---NLMEKDPNKRYTCEQAARHPW----IAG--------DT 283

Query: 297 SLSRNTMECSGPQDSKELLQNSQSRQA 323
           +L++N  E    Q  K   + S+ RQA
Sbjct: 284 ALNKNIHESVSAQIRKNFAK-SKWRQA 309


>gi|4557511 death-associated protein kinase 3 [Homo sapiens]
          Length = 454

 Score =  120 bits (300), Expect = 1e-26
 Identities = 88/296 (29%), Positives = 140/296 (47%), Gaps = 43/296 (14%)

Query: 2   ENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---------RPEITNWVRLTRE 52
           +++ + EE+G G   +V K R+KGT    A     K +         R EI   V + RE
Sbjct: 11  DHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNILRE 70

Query: 53  IKHKNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHL 112
           I+H NI+T H+ +E    + L++EL +GG L   +A+ E+L ED   +F   ++ G+H+L
Sbjct: 71  IRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYL 130

Query: 113 HKLGILFCDISPRKILLEGPGT----LKFSNFCLA-KVEGENLEEFFALVAAEEGGGDNG 167
           H   I   D+ P  I+L         +K  +F +A K+E  N  EF              
Sbjct: 131 HSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGN--EF-------------- 174

Query: 168 ENVLKKSMKSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISEL 227
                      + G+P + APE+V      + +D+WS+G + Y + SG  PF  E+  E 
Sbjct: 175 ---------KNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQET 225

Query: 228 TEKILCEDPLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKA 283
              I   +        S+  + + DFI     LL +DP++R+T  + L+HS W KA
Sbjct: 226 LTNISAVNYDFDEEYFSNTSELAKDFIR---RLLVKDPKRRMTIAQSLEHS-WIKA 277


>gi|29826329 p21-activated kinase 7 [Homo sapiens]
          Length = 719

 Score =  117 bits (292), Expect = 9e-26
 Identities = 93/286 (32%), Positives = 136/286 (47%), Gaps = 34/286 (11%)

Query: 1   MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---RPEITNWVRLTREIKHKN 57
           + NFI   +IG GS  +V     K T   VA+   D  K   R  + N V + R+  H N
Sbjct: 449 LANFI---KIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDN 505

Query: 58  IVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGI 117
           +V  +  Y   + LW+V+E   GG+L  ++     + E+ +    + ++  L +LH  G+
Sbjct: 506 VVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTR-MNEEQIATVCLSVLRALSYLHNQGV 564

Query: 118 LFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKS 177
           +  DI    ILL   G +K S+F            F A V+ E         V K+  KS
Sbjct: 565 IHRDIKSDSILLTSDGRIKLSDF-----------GFCAQVSKE---------VPKR--KS 602

Query: 178 RVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPL 237
            V G+P + APEV+    +    D+WSLG ++ EM  G+PP+F+E   +   +I   D L
Sbjct: 603 LV-GTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRI--RDSL 659

Query: 238 PPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKA 283
           PP  KD    K SS     LD +L R+P +R T   LL H F K A
Sbjct: 660 PPRVKDLH--KVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLA 703


>gi|24308191 p21-activated kinase 7 [Homo sapiens]
          Length = 719

 Score =  117 bits (292), Expect = 9e-26
 Identities = 93/286 (32%), Positives = 136/286 (47%), Gaps = 34/286 (11%)

Query: 1   MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---RPEITNWVRLTREIKHKN 57
           + NFI   +IG GS  +V     K T   VA+   D  K   R  + N V + R+  H N
Sbjct: 449 LANFI---KIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHDN 505

Query: 58  IVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGI 117
           +V  +  Y   + LW+V+E   GG+L  ++     + E+ +    + ++  L +LH  G+
Sbjct: 506 VVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTR-MNEEQIATVCLSVLRALSYLHNQGV 564

Query: 118 LFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKS 177
           +  DI    ILL   G +K S+F            F A V+ E         V K+  KS
Sbjct: 565 IHRDIKSDSILLTSDGRIKLSDF-----------GFCAQVSKE---------VPKR--KS 602

Query: 178 RVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPL 237
            V G+P + APEV+    +    D+WSLG ++ EM  G+PP+F+E   +   +I   D L
Sbjct: 603 LV-GTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRI--RDSL 659

Query: 238 PPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKA 283
           PP  KD    K SS     LD +L R+P +R T   LL H F K A
Sbjct: 660 PPRVKDLH--KVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLA 703


>gi|217330559 unc-51-like kinase 2 [Homo sapiens]
          Length = 1036

 Score =  116 bits (291), Expect = 1e-25
 Identities = 83/278 (29%), Positives = 140/278 (50%), Gaps = 30/278 (10%)

Query: 10  IGRGSKTVVYKGRRKGTINF-VAILCTDKCKRPE----ITNWVRLTREIKHKNIVTFHEW 64
           +G G+  VV++GR +   ++ VAI   +K    +    +   +++ +E++H+NIV  ++ 
Sbjct: 15  VGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDV 74

Query: 65  YETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDISP 124
            E  N ++LV+E C GG L   +     L ED +R F   + + +  LH  GI+  D+ P
Sbjct: 75  QELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKP 134

Query: 125 RKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSPV 184
           + IL      L ++N   + V G  ++       A+ G       +    M + + GSP+
Sbjct: 135 QNIL------LSYANRRKSSVSGIRIK------IADFG---FARYLHSNMMAATLCGSPM 179

Query: 185 YTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELT---EKILCEDPLPPIP 241
           Y APEV+    +   +DLWS+G ++Y+   GKPPF + S  +L    EK      +P IP
Sbjct: 180 YMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEK--NRSLMPSIP 237

Query: 242 KDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSF 279
           +++S   A     NLL GLLQR+ + R+ +     H F
Sbjct: 238 RETSPYLA-----NLLLGLLQRNQKDRMDFEAFFSHPF 270


>gi|217330557 unc-51-like kinase 2 [Homo sapiens]
          Length = 1036

 Score =  116 bits (291), Expect = 1e-25
 Identities = 83/278 (29%), Positives = 140/278 (50%), Gaps = 30/278 (10%)

Query: 10  IGRGSKTVVYKGRRKGTINF-VAILCTDKCKRPE----ITNWVRLTREIKHKNIVTFHEW 64
           +G G+  VV++GR +   ++ VAI   +K    +    +   +++ +E++H+NIV  ++ 
Sbjct: 15  VGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDV 74

Query: 65  YETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDISP 124
            E  N ++LV+E C GG L   +     L ED +R F   + + +  LH  GI+  D+ P
Sbjct: 75  QELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKP 134

Query: 125 RKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSPV 184
           + IL      L ++N   + V G  ++       A+ G       +    M + + GSP+
Sbjct: 135 QNIL------LSYANRRKSSVSGIRIK------IADFG---FARYLHSNMMAATLCGSPM 179

Query: 185 YTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELT---EKILCEDPLPPIP 241
           Y APEV+    +   +DLWS+G ++Y+   GKPPF + S  +L    EK      +P IP
Sbjct: 180 YMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEK--NRSLMPSIP 237

Query: 242 KDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSF 279
           +++S   A     NLL GLLQR+ + R+ +     H F
Sbjct: 238 RETSPYLA-----NLLLGLLQRNQKDRMDFEAFFSHPF 270


>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
           kinase isoform b [Homo sapiens]
          Length = 360

 Score =  114 bits (286), Expect = 5e-25
 Identities = 80/277 (28%), Positives = 128/277 (46%), Gaps = 35/277 (12%)

Query: 8   EEIGRGSKTVVYKGRRKGTINFVAILCTDKC----KRPEITNWVRLTREIKHKNIVTFHE 63
           E +G G+ + V   + +G+ + VA+ C  K     K   + N + + R I H NIV   +
Sbjct: 36  ERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIVALED 95

Query: 64  WYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDIS 123
            +E+ +HL+L +EL TGG L   I +  +  E         ++  + +LH LGI+  D+ 
Sbjct: 96  VHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLK 155

Query: 124 PRKILLEGP---GTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVK 180
           P  +L   P     +  S+F L+K++  N                         M     
Sbjct: 156 PENLLYATPFEDSKIMVSDFGLSKIQAGN-------------------------MLGTAC 190

Query: 181 GSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPI 240
           G+P Y APE++    +  + D+W+LG + Y +  G PPF+ ES  EL  +IL        
Sbjct: 191 GTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDS 250

Query: 241 PKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQH 277
           P      +++ DFI     LL+RDPQKR T  + L+H
Sbjct: 251 PFWDDISESAKDFIR---HLLERDPQKRFTCQQALRH 284


>gi|209364619 pregnancy upregulated non-ubiquitously expressed CaM
           kinase isoform a [Homo sapiens]
          Length = 426

 Score =  114 bits (286), Expect = 5e-25
 Identities = 80/277 (28%), Positives = 128/277 (46%), Gaps = 35/277 (12%)

Query: 8   EEIGRGSKTVVYKGRRKGTINFVAILCTDKC----KRPEITNWVRLTREIKHKNIVTFHE 63
           E +G G+ + V   + +G+ + VA+ C  K     K   + N + + R I H NIV   +
Sbjct: 102 ERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIVALED 161

Query: 64  WYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDIS 123
            +E+ +HL+L +EL TGG L   I +  +  E         ++  + +LH LGI+  D+ 
Sbjct: 162 VHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLK 221

Query: 124 PRKILLEGP---GTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVK 180
           P  +L   P     +  S+F L+K++  N                         M     
Sbjct: 222 PENLLYATPFEDSKIMVSDFGLSKIQAGN-------------------------MLGTAC 256

Query: 181 GSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPI 240
           G+P Y APE++    +  + D+W+LG + Y +  G PPF+ ES  EL  +IL        
Sbjct: 257 GTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDS 316

Query: 241 PKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQH 277
           P      +++ DFI     LL+RDPQKR T  + L+H
Sbjct: 317 PFWDDISESAKDFIR---HLLERDPQKRFTCQQALRH 350


>gi|191252782 p21-activated kinase 6 [Homo sapiens]
          Length = 681

 Score =  114 bits (284), Expect = 8e-25
 Identities = 82/276 (29%), Positives = 135/276 (48%), Gaps = 31/276 (11%)

Query: 7   YEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---RPEITNWVRLTREIKHKNIVTFHE 63
           Y +IG GS  +V   R K +   VA+   D  K   R  + N V + R+ +H N+V  ++
Sbjct: 410 YVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYK 469

Query: 64  WYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDIS 123
            Y     LW+++E   GG+L  +++Q   L E+ +      ++  L +LH  G++  DI 
Sbjct: 470 SYLVGEELWVLMEFLQGGALTDIVSQ-VRLNEEQIATVCEAVLQALAYLHAQGVIHRDIK 528

Query: 124 PRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSP 183
              ILL   G +K S+F       +++ +  +LV                       G+P
Sbjct: 529 SDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLV-----------------------GTP 565

Query: 184 VYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPIPKD 243
            + APEV+  + ++   D+WSLG ++ EM  G+PP+FS+S  +  +++   D  PP  K+
Sbjct: 566 YWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRL--RDSPPPKLKN 623

Query: 244 SSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSF 279
           S   K S    + L+ +L RDPQ+R T   LL H F
Sbjct: 624 SH--KVSPVLRDFLERMLVRDPQERATAQELLDHPF 657


>gi|191252780 p21-activated kinase 6 [Homo sapiens]
          Length = 681

 Score =  114 bits (284), Expect = 8e-25
 Identities = 82/276 (29%), Positives = 135/276 (48%), Gaps = 31/276 (11%)

Query: 7   YEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---RPEITNWVRLTREIKHKNIVTFHE 63
           Y +IG GS  +V   R K +   VA+   D  K   R  + N V + R+ +H N+V  ++
Sbjct: 410 YVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYK 469

Query: 64  WYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDIS 123
            Y     LW+++E   GG+L  +++Q   L E+ +      ++  L +LH  G++  DI 
Sbjct: 470 SYLVGEELWVLMEFLQGGALTDIVSQ-VRLNEEQIATVCEAVLQALAYLHAQGVIHRDIK 528

Query: 124 PRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSP 183
              ILL   G +K S+F       +++ +  +LV                       G+P
Sbjct: 529 SDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLV-----------------------GTP 565

Query: 184 VYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPIPKD 243
            + APEV+  + ++   D+WSLG ++ EM  G+PP+FS+S  +  +++   D  PP  K+
Sbjct: 566 YWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRL--RDSPPPKLKN 623

Query: 244 SSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSF 279
           S   K S    + L+ +L RDPQ+R T   LL H F
Sbjct: 624 SH--KVSPVLRDFLERMLVRDPQERATAQELLDHPF 657


>gi|9910476 p21-activated kinase 6 [Homo sapiens]
          Length = 681

 Score =  114 bits (284), Expect = 8e-25
 Identities = 82/276 (29%), Positives = 135/276 (48%), Gaps = 31/276 (11%)

Query: 7   YEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---RPEITNWVRLTREIKHKNIVTFHE 63
           Y +IG GS  +V   R K +   VA+   D  K   R  + N V + R+ +H N+V  ++
Sbjct: 410 YVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYK 469

Query: 64  WYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDIS 123
            Y     LW+++E   GG+L  +++Q   L E+ +      ++  L +LH  G++  DI 
Sbjct: 470 SYLVGEELWVLMEFLQGGALTDIVSQ-VRLNEEQIATVCEAVLQALAYLHAQGVIHRDIK 528

Query: 124 PRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVKGSP 183
              ILL   G +K S+F       +++ +  +LV                       G+P
Sbjct: 529 SDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLV-----------------------GTP 565

Query: 184 VYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPIPKD 243
            + APEV+  + ++   D+WSLG ++ EM  G+PP+FS+S  +  +++   D  PP  K+
Sbjct: 566 YWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRL--RDSPPPKLKN 623

Query: 244 SSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSF 279
           S   K S    + L+ +L RDPQ+R T   LL H F
Sbjct: 624 SH--KVSPVLRDFLERMLVRDPQERATAQELLDHPF 657


>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
           sapiens]
          Length = 370

 Score =  112 bits (280), Expect = 2e-24
 Identities = 82/275 (29%), Positives = 130/275 (47%), Gaps = 34/275 (12%)

Query: 10  IGRGSKTVVYKGRRKGTINFVAILCTDK----CKRPEITNWVRLTREIKHKNIVTFHEWY 65
           +G G+ + V     K T   VAI C  K     K   + N + +  +IKH NIV   + Y
Sbjct: 26  LGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIY 85

Query: 66  ETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDISPR 125
           E+  HL+L+++L +GG L   I +     E         ++  + +LH LGI+  D+ P 
Sbjct: 86  ESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPE 145

Query: 126 KIL---LEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKSRVKGS 182
            +L   L+    +  S+F L+K+E                  D G      S+ S   G+
Sbjct: 146 NLLYYSLDEDSKIMISDFGLSKME------------------DPG------SVLSTACGT 181

Query: 183 PVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPIPK 242
           P Y APEV+    +S + D WS+G + Y +  G PPF+ E+ ++L E+IL  +     P 
Sbjct: 182 PGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPY 241

Query: 243 DSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQH 277
                 ++ DFI     L+++DP+KR T  + LQH
Sbjct: 242 WDDISDSAKDFIR---HLMEKDPEKRFTCEQALQH 273


>gi|25168263 serum/glucocorticoid regulated kinase 1 isoform 1 [Homo
           sapiens]
          Length = 431

 Score =  111 bits (278), Expect = 4e-24
 Identities = 81/274 (29%), Positives = 129/274 (47%), Gaps = 37/274 (13%)

Query: 3   NFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDK---CKRPEITNWVR----LTREIKH 55
           +F   + IG+GS   V   R K    F A+    K    K+ E  + +     L + +KH
Sbjct: 97  DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 156

Query: 56  KNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKL 115
             +V  H  ++T++ L+ V++   GG L   + ++    E   R +  ++ S L +LH L
Sbjct: 157 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 216

Query: 116 GILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSM 175
            I++ D+ P  ILL+  G +  ++F L K                       EN+   S 
Sbjct: 217 NIVYRDLKPENILLDSQGHIVLTDFGLCK-----------------------ENIEHNST 253

Query: 176 KSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCED 235
            S   G+P Y APEV+    +  + D W LG +LYEM  G PPF+S + +E+ + IL   
Sbjct: 254 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNIL-NK 312

Query: 236 PLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRL 269
           PL        +P  ++   +LL+GLLQ+D  KRL
Sbjct: 313 PL------QLKPNITNSARHLLEGLLQKDRTKRL 340


>gi|219521880 serum/glucocorticoid regulated kinase 1 isoform 4
           [Homo sapiens]
          Length = 445

 Score =  111 bits (278), Expect = 4e-24
 Identities = 81/274 (29%), Positives = 129/274 (47%), Gaps = 37/274 (13%)

Query: 3   NFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDK---CKRPEITNWVR----LTREIKH 55
           +F   + IG+GS   V   R K    F A+    K    K+ E  + +     L + +KH
Sbjct: 111 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 170

Query: 56  KNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKL 115
             +V  H  ++T++ L+ V++   GG L   + ++    E   R +  ++ S L +LH L
Sbjct: 171 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 230

Query: 116 GILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSM 175
            I++ D+ P  ILL+  G +  ++F L K                       EN+   S 
Sbjct: 231 NIVYRDLKPENILLDSQGHIVLTDFGLCK-----------------------ENIEHNST 267

Query: 176 KSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCED 235
            S   G+P Y APEV+    +  + D W LG +LYEM  G PPF+S + +E+ + IL   
Sbjct: 268 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNIL-NK 326

Query: 236 PLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRL 269
           PL        +P  ++   +LL+GLLQ+D  KRL
Sbjct: 327 PL------QLKPNITNSARHLLEGLLQKDRTKRL 354


>gi|219521878 serum/glucocorticoid regulated kinase 1 isoform 3
           [Homo sapiens]
          Length = 459

 Score =  111 bits (278), Expect = 4e-24
 Identities = 81/274 (29%), Positives = 129/274 (47%), Gaps = 37/274 (13%)

Query: 3   NFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDK---CKRPEITNWVR----LTREIKH 55
           +F   + IG+GS   V   R K    F A+    K    K+ E  + +     L + +KH
Sbjct: 125 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 184

Query: 56  KNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKL 115
             +V  H  ++T++ L+ V++   GG L   + ++    E   R +  ++ S L +LH L
Sbjct: 185 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 244

Query: 116 GILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSM 175
            I++ D+ P  ILL+  G +  ++F L K                       EN+   S 
Sbjct: 245 NIVYRDLKPENILLDSQGHIVLTDFGLCK-----------------------ENIEHNST 281

Query: 176 KSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCED 235
            S   G+P Y APEV+    +  + D W LG +LYEM  G PPF+S + +E+ + IL   
Sbjct: 282 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNIL-NK 340

Query: 236 PLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRL 269
           PL        +P  ++   +LL+GLLQ+D  KRL
Sbjct: 341 PL------QLKPNITNSARHLLEGLLQKDRTKRL 368


>gi|219521876 serum/glucocorticoid regulated kinase 1 isoform 2
           [Homo sapiens]
          Length = 526

 Score =  111 bits (278), Expect = 4e-24
 Identities = 81/274 (29%), Positives = 129/274 (47%), Gaps = 37/274 (13%)

Query: 3   NFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDK---CKRPEITNWVR----LTREIKH 55
           +F   + IG+GS   V   R K    F A+    K    K+ E  + +     L + +KH
Sbjct: 192 DFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKH 251

Query: 56  KNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKL 115
             +V  H  ++T++ L+ V++   GG L   + ++    E   R +  ++ S L +LH L
Sbjct: 252 PFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSL 311

Query: 116 GILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSM 175
            I++ D+ P  ILL+  G +  ++F L K                       EN+   S 
Sbjct: 312 NIVYRDLKPENILLDSQGHIVLTDFGLCK-----------------------ENIEHNST 348

Query: 176 KSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCED 235
            S   G+P Y APEV+    +  + D W LG +LYEM  G PPF+S + +E+ + IL   
Sbjct: 349 TSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNIL-NK 407

Query: 236 PLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRL 269
           PL        +P  ++   +LL+GLLQ+D  KRL
Sbjct: 408 PL------QLKPNITNSARHLLEGLLQKDRTKRL 435


>gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens]
          Length = 591

 Score =  111 bits (277), Expect = 5e-24
 Identities = 85/286 (29%), Positives = 133/286 (46%), Gaps = 34/286 (11%)

Query: 1   MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---RPEITNWVRLTREIKHKN 57
           ++NFI   +IG GS  +V     + +   VA+   D  K   R  + N V + R+ +H+N
Sbjct: 321 LDNFI---KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 377

Query: 58  IVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGI 117
           +V  +  Y   + LW+V+E   GG+L  ++     + E+ +    + ++  L  LH  G+
Sbjct: 378 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTR-MNEEQIAAVCLAVLQALSVLHAQGV 436

Query: 118 LFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKS 177
           +  DI    ILL   G +K S+F            F A V+ E               + 
Sbjct: 437 IHRDIKSDSILLTHDGRVKLSDF-----------GFCAQVSKEV------------PRRK 473

Query: 178 RVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPL 237
            + G+P + APE++    +    D+WSLG ++ EM  G+PP+F+E    L    +  D L
Sbjct: 474 SLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNE--PPLKAMKMIRDNL 531

Query: 238 PPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKA 283
           PP  K+    K S      LD LL RDP +R T   LL+H F  KA
Sbjct: 532 PPRLKNLH--KVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKA 575


>gi|62422561 p21-activated kinase 4 isoform 2 [Homo sapiens]
          Length = 438

 Score =  111 bits (277), Expect = 5e-24
 Identities = 85/286 (29%), Positives = 133/286 (46%), Gaps = 34/286 (11%)

Query: 1   MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---RPEITNWVRLTREIKHKN 57
           ++NFI   +IG GS  +V     + +   VA+   D  K   R  + N V + R+ +H+N
Sbjct: 168 LDNFI---KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 224

Query: 58  IVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGI 117
           +V  +  Y   + LW+V+E   GG+L  ++     + E+ +    + ++  L  LH  G+
Sbjct: 225 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTR-MNEEQIAAVCLAVLQALSVLHAQGV 283

Query: 118 LFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKS 177
           +  DI    ILL   G +K S+F            F A V+ E               + 
Sbjct: 284 IHRDIKSDSILLTHDGRVKLSDF-----------GFCAQVSKEV------------PRRK 320

Query: 178 RVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPL 237
            + G+P + APE++    +    D+WSLG ++ EM  G+PP+F+E    L    +  D L
Sbjct: 321 SLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNE--PPLKAMKMIRDNL 378

Query: 238 PPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKA 283
           PP  K+    K S      LD LL RDP +R T   LL+H F  KA
Sbjct: 379 PPRLKNLH--KVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKA 422


>gi|62422563 p21-activated kinase 4 isoform 2 [Homo sapiens]
          Length = 438

 Score =  111 bits (277), Expect = 5e-24
 Identities = 85/286 (29%), Positives = 133/286 (46%), Gaps = 34/286 (11%)

Query: 1   MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---RPEITNWVRLTREIKHKN 57
           ++NFI   +IG GS  +V     + +   VA+   D  K   R  + N V + R+ +H+N
Sbjct: 168 LDNFI---KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 224

Query: 58  IVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGI 117
           +V  +  Y   + LW+V+E   GG+L  ++     + E+ +    + ++  L  LH  G+
Sbjct: 225 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTR-MNEEQIAAVCLAVLQALSVLHAQGV 283

Query: 118 LFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKS 177
           +  DI    ILL   G +K S+F            F A V+ E               + 
Sbjct: 284 IHRDIKSDSILLTHDGRVKLSDF-----------GFCAQVSKEV------------PRRK 320

Query: 178 RVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPL 237
            + G+P + APE++    +    D+WSLG ++ EM  G+PP+F+E    L    +  D L
Sbjct: 321 SLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNE--PPLKAMKMIRDNL 378

Query: 238 PPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKA 283
           PP  K+    K S      LD LL RDP +R T   LL+H F  KA
Sbjct: 379 PPRLKNLH--KVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKA 422


>gi|62422557 p21-activated kinase 4 isoform 1 [Homo sapiens]
          Length = 591

 Score =  111 bits (277), Expect = 5e-24
 Identities = 85/286 (29%), Positives = 133/286 (46%), Gaps = 34/286 (11%)

Query: 1   MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---RPEITNWVRLTREIKHKN 57
           ++NFI   +IG GS  +V     + +   VA+   D  K   R  + N V + R+ +H+N
Sbjct: 321 LDNFI---KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 377

Query: 58  IVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGI 117
           +V  +  Y   + LW+V+E   GG+L  ++     + E+ +    + ++  L  LH  G+
Sbjct: 378 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTR-MNEEQIAAVCLAVLQALSVLHAQGV 436

Query: 118 LFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKS 177
           +  DI    ILL   G +K S+F            F A V+ E               + 
Sbjct: 437 IHRDIKSDSILLTHDGRVKLSDF-----------GFCAQVSKEV------------PRRK 473

Query: 178 RVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPL 237
            + G+P + APE++    +    D+WSLG ++ EM  G+PP+F+E    L    +  D L
Sbjct: 474 SLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNE--PPLKAMKMIRDNL 531

Query: 238 PPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKA 283
           PP  K+    K S      LD LL RDP +R T   LL+H F  KA
Sbjct: 532 PPRLKNLH--KVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKA 575


>gi|5031975 p21-activated kinase 4 isoform 1 [Homo sapiens]
          Length = 591

 Score =  111 bits (277), Expect = 5e-24
 Identities = 85/286 (29%), Positives = 133/286 (46%), Gaps = 34/286 (11%)

Query: 1   MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCK---RPEITNWVRLTREIKHKN 57
           ++NFI   +IG GS  +V     + +   VA+   D  K   R  + N V + R+ +H+N
Sbjct: 321 LDNFI---KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHEN 377

Query: 58  IVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGI 117
           +V  +  Y   + LW+V+E   GG+L  ++     + E+ +    + ++  L  LH  G+
Sbjct: 378 VVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTR-MNEEQIAAVCLAVLQALSVLHAQGV 436

Query: 118 LFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSMKS 177
           +  DI    ILL   G +K S+F            F A V+ E               + 
Sbjct: 437 IHRDIKSDSILLTHDGRVKLSDF-----------GFCAQVSKEV------------PRRK 473

Query: 178 RVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPL 237
            + G+P + APE++    +    D+WSLG ++ EM  G+PP+F+E    L    +  D L
Sbjct: 474 SLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNE--PPLKAMKMIRDNL 531

Query: 238 PPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKA 283
           PP  K+    K S      LD LL RDP +R T   LL+H F  KA
Sbjct: 532 PPRLKNLH--KVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKA 575


>gi|121114283 polo-like kinase 4 [Homo sapiens]
          Length = 970

 Score =  108 bits (270), Expect = 3e-23
 Identities = 79/303 (26%), Positives = 144/303 (47%), Gaps = 38/303 (12%)

Query: 1   MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKR------PEITNWVRLTREIK 54
           +E+F +   +G+GS   VY+     T   VAI   DK           + N V++  ++K
Sbjct: 9   IEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLK 68

Query: 55  HKNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQD-ENLPEDVVREFGIDLISGLHHLH 113
           H +I+  + ++E SN+++LV+E+C  G +   +    +   E+  R F   +I+G+ +LH
Sbjct: 69  HPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLH 128

Query: 114 KLGILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKK 173
             GIL  D++   +LL     +K ++F LA       E+ + L                 
Sbjct: 129 SHGILHRDLTLSNLLLTRNMNIKIADFGLATQLKMPHEKHYTLC---------------- 172

Query: 174 SMKSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILC 233
                  G+P Y +PE+   +   + SD+WSLGC+ Y +  G+PPF ++++     K++ 
Sbjct: 173 -------GTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTLNKVVL 225

Query: 234 EDPLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKAFAGADQE-SS 292
            D   P          S +  +L+  LL+R+P  RL+ + +L H F  +  +   ++  +
Sbjct: 226 ADYEMP-------SFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMSRNSSTKSKDLGT 278

Query: 293 VED 295
           VED
Sbjct: 279 VED 281


>gi|31563382 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
           sapiens]
          Length = 496

 Score =  108 bits (270), Expect = 3e-23
 Identities = 78/274 (28%), Positives = 127/274 (46%), Gaps = 37/274 (13%)

Query: 3   NFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDK---CKRPEITNWVR----LTREIKH 55
           +F   + IG+GS   V   +RK    F A+    K     R E  + +     L + +KH
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220

Query: 56  KNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKL 115
             +V  H  ++T+  L+ V++   GG L   + ++ + PE   R +  ++ S L +LH +
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280

Query: 116 GILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSM 175
            I++ D+ P  ILL+  G +  ++F L K                       E +     
Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCK-----------------------EGIAISDT 317

Query: 176 KSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCED 235
            +   G+P Y APEV+R   +  + D W LG +LYEM  G PPF+   ++E+ + IL   
Sbjct: 318 TTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNIL-HK 376

Query: 236 PLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRL 269
           PL      S RP  S    ++L+ LL++D Q RL
Sbjct: 377 PL------SLRPGVSLTAWSILEELLEKDRQNRL 404


>gi|75813626 serum/glucocorticoid regulated kinase 3 isoform 1 [Homo
           sapiens]
          Length = 496

 Score =  108 bits (270), Expect = 3e-23
 Identities = 78/274 (28%), Positives = 127/274 (46%), Gaps = 37/274 (13%)

Query: 3   NFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDK---CKRPEITNWVR----LTREIKH 55
           +F   + IG+GS   V   +RK    F A+    K     R E  + +     L + +KH
Sbjct: 161 DFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKH 220

Query: 56  KNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKL 115
             +V  H  ++T+  L+ V++   GG L   + ++ + PE   R +  ++ S L +LH +
Sbjct: 221 PFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSI 280

Query: 116 GILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKKSM 175
            I++ D+ P  ILL+  G +  ++F L K                       E +     
Sbjct: 281 KIVYRDLKPENILLDSVGHVVLTDFGLCK-----------------------EGIAISDT 317

Query: 176 KSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCED 235
            +   G+P Y APEV+R   +  + D W LG +LYEM  G PPF+   ++E+ + IL   
Sbjct: 318 TTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNIL-HK 376

Query: 236 PLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRL 269
           PL      S RP  S    ++L+ LL++D Q RL
Sbjct: 377 PL------SLRPGVSLTAWSILEELLEKDRQNRL 404


>gi|133908623 protein kinase C, iota [Homo sapiens]
          Length = 596

 Score =  107 bits (267), Expect = 7e-23
 Identities = 79/283 (27%), Positives = 131/283 (46%), Gaps = 42/283 (14%)

Query: 1   MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDK--CKRPEITNWVRLTREI----- 53
           +++F L   IGRGS   V   R K T    A+    K      E  +WV+  + +     
Sbjct: 251 LQDFDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQAS 310

Query: 54  KHKNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLH 113
            H  +V  H  ++T + L+ V+E   GG L   + +   LPE+  R +  ++   L++LH
Sbjct: 311 NHPFLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLH 370

Query: 114 KLGILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEEGGGDNGENVLKK 173
           + GI++ D+    +LL+  G +K +++ + K                       E +   
Sbjct: 371 ERGIIYRDLKLDNVLLDSEGHIKLTDYGMCK-----------------------EGLRPG 407

Query: 174 SMKSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPF----FSESISELTE 229
              S   G+P Y APE++RG D+  S D W+LG L++EM +G+ PF     S++  + TE
Sbjct: 408 DTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTE 467

Query: 230 KILCEDPLPP---IPKDSSRPKASSDFINLLDGLLQRDPQKRL 269
             L +  L     IP+  S   AS     +L   L +DP++RL
Sbjct: 468 DYLFQVILEKQIRIPRSLSVKAAS-----VLKSFLNKDPKERL 505


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,581,435
Number of Sequences: 37866
Number of extensions: 2136945
Number of successful extensions: 7253
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 553
Number of HSP's successfully gapped in prelim test: 194
Number of HSP's that attempted gapping in prelim test: 5382
Number of HSP's gapped (non-prelim): 1178
length of query: 1275
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1161
effective length of database: 13,930,794
effective search space: 16173651834
effective search space used: 16173651834
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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