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Search of human proteins with 15029528
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15029528 G protein-coupled receptor 18 [Homo sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148235349 G protein-coupled receptor 18 [Homo sapiens] 667 0.0
gi|15029528 G protein-coupled receptor 18 [Homo sapiens] 667 0.0
gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens] 137 1e-32
gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens] 137 1e-32
gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens] 137 1e-32
gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens] 137 1e-32
gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo sa... 137 1e-32
gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo sa... 137 1e-32
gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo sap... 137 1e-32
gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens] 131 1e-30
gi|148225857 G protein-coupled receptor 34 [Homo sapiens] 131 1e-30
gi|4885319 G protein-coupled receptor 34 [Homo sapiens] 131 1e-30
gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo ... 129 5e-30
gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] 127 1e-29
gi|4505557 purinergic receptor P2Y1 [Homo sapiens] 123 2e-28
gi|4885121 chemokine (C-C motif) receptor 8 [Homo sapiens] 120 2e-27
gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens] 119 4e-27
gi|34577052 coagulation factor II (thrombin) receptor-like 1 pre... 117 1e-26
gi|4885057 apelin receptor [Homo sapiens] 115 4e-26
gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens] 115 5e-26
gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens] 114 1e-25
gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens] 114 1e-25
gi|37187860 chemokine (C-C motif) receptor 6 [Homo sapiens] 113 2e-25
gi|37188165 chemokine (C-C motif) receptor 6 [Homo sapiens] 113 2e-25
gi|4502641 chemokine (C-C motif) receptor 7 precursor [Homo sapi... 113 2e-25
gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo sap... 113 2e-25
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 112 5e-25
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 112 6e-25
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 112 6e-25
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 112 6e-25
>gi|148235349 G protein-coupled receptor 18 [Homo sapiens]
Length = 331
Score = 667 bits (1721), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIY 60
MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIY
Sbjct: 1 MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIY 60
Query: 61 MMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRY 120
MMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRY
Sbjct: 61 MMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRY 120
Query: 121 MAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIY 180
MAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIY
Sbjct: 121 MAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIY 180
Query: 181 LKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQ 240
LKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQ
Sbjct: 181 LKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQ 240
Query: 241 VLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISV 300
VLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISV
Sbjct: 241 VLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISV 300
Query: 301 MLYRNYLRSMRRKSFRSGSLRSLSNINSEML 331
MLYRNYLRSMRRKSFRSGSLRSLSNINSEML
Sbjct: 301 MLYRNYLRSMRRKSFRSGSLRSLSNINSEML 331
>gi|15029528 G protein-coupled receptor 18 [Homo sapiens]
Length = 331
Score = 667 bits (1721), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIY 60
MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIY
Sbjct: 1 MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIY 60
Query: 61 MMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRY 120
MMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRY
Sbjct: 61 MMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRY 120
Query: 121 MAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIY 180
MAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIY
Sbjct: 121 MAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIY 180
Query: 181 LKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQ 240
LKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQ
Sbjct: 181 LKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQ 240
Query: 241 VLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISV 300
VLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISV
Sbjct: 241 VLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISV 300
Query: 301 MLYRNYLRSMRRKSFRSGSLRSLSNINSEML 331
MLYRNYLRSMRRKSFRSGSLRSLSNINSEML
Sbjct: 301 MLYRNYLRSMRRKSFRSGSLRSLSNINSEML 331
>gi|238814307 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 137 bits (346), Expect = 1e-32
Identities = 86/288 (29%), Positives = 150/288 (52%), Gaps = 26/288 (9%)
Query: 28 FYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFY-YAKDE 86
FY FI+ L N ALW+F K T +++M++A+ DL ++ LP R+ Y ++ +
Sbjct: 37 FYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNH 96
Query: 87 WPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVW 146
WPFGE C++ G L +++ L ISADR++AIV P + +L+ A LAC +W
Sbjct: 97 WPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLW 156
Query: 147 IMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGC 206
++ PLL+ + + T CL+ +Y + + L L F P + C
Sbjct: 157 VVVAVAMAPLLVSPQTVQTNHT-VVCLQ----LYREKASHHALVSLAVAFTFPFITTVTC 211
Query: 207 YLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNP 266
YL+II +L G +++ ++K K++R+I +L LVCF+P+H+ + +L Y
Sbjct: 212 YLLIIRSLRQG--LRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVL-----HYRS 264
Query: 267 WGA-------------FTTFLMNLSTCLDVILYYIVSKQFQARVISVM 301
GA T+ L +L+ LD I+Y+ V+++F+ + +++
Sbjct: 265 HGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLL 312
>gi|238814305 G protein-coupled receptor 17 isoform b [Homo sapiens]
Length = 339
Score = 137 bits (346), Expect = 1e-32
Identities = 86/288 (29%), Positives = 150/288 (52%), Gaps = 26/288 (9%)
Query: 28 FYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFY-YAKDE 86
FY FI+ L N ALW+F K T +++M++A+ DL ++ LP R+ Y ++ +
Sbjct: 37 FYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNH 96
Query: 87 WPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVW 146
WPFGE C++ G L +++ L ISADR++AIV P + +L+ A LAC +W
Sbjct: 97 WPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLW 156
Query: 147 IMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGC 206
++ PLL+ + + T CL+ +Y + + L L F P + C
Sbjct: 157 VVVAVAMAPLLVSPQTVQTNHT-VVCLQ----LYREKASHHALVSLAVAFTFPFITTVTC 211
Query: 207 YLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNP 266
YL+II +L G +++ ++K K++R+I +L LVCF+P+H+ + +L Y
Sbjct: 212 YLLIIRSLRQG--LRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVL-----HYRS 264
Query: 267 WGA-------------FTTFLMNLSTCLDVILYYIVSKQFQARVISVM 301
GA T+ L +L+ LD I+Y+ V+++F+ + +++
Sbjct: 265 HGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLL 312
>gi|4885301 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 137 bits (346), Expect = 1e-32
Identities = 86/288 (29%), Positives = 150/288 (52%), Gaps = 26/288 (9%)
Query: 28 FYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFY-YAKDE 86
FY FI+ L N ALW+F K T +++M++A+ DL ++ LP R+ Y ++ +
Sbjct: 65 FYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNH 124
Query: 87 WPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVW 146
WPFGE C++ G L +++ L ISADR++AIV P + +L+ A LAC +W
Sbjct: 125 WPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLW 184
Query: 147 IMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGC 206
++ PLL+ + + T CL+ +Y + + L L F P + C
Sbjct: 185 VVVAVAMAPLLVSPQTVQTNHT-VVCLQ----LYREKASHHALVSLAVAFTFPFITTVTC 239
Query: 207 YLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNP 266
YL+II +L G +++ ++K K++R+I +L LVCF+P+H+ + +L Y
Sbjct: 240 YLLIIRSLRQG--LRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVL-----HYRS 292
Query: 267 WGA-------------FTTFLMNLSTCLDVILYYIVSKQFQARVISVM 301
GA T+ L +L+ LD I+Y+ V+++F+ + +++
Sbjct: 293 HGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLL 340
>gi|238814302 G protein-coupled receptor 17 isoform a [Homo sapiens]
Length = 367
Score = 137 bits (346), Expect = 1e-32
Identities = 86/288 (29%), Positives = 150/288 (52%), Gaps = 26/288 (9%)
Query: 28 FYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFY-YAKDE 86
FY FI+ L N ALW+F K T +++M++A+ DL ++ LP R+ Y ++ +
Sbjct: 65 FYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNH 124
Query: 87 WPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVW 146
WPFGE C++ G L +++ L ISADR++AIV P + +L+ A LAC +W
Sbjct: 125 WPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLW 184
Query: 147 IMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGC 206
++ PLL+ + + T CL+ +Y + + L L F P + C
Sbjct: 185 VVVAVAMAPLLVSPQTVQTNHT-VVCLQ----LYREKASHHALVSLAVAFTFPFITTVTC 239
Query: 207 YLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNP 266
YL+II +L G +++ ++K K++R+I +L LVCF+P+H+ + +L Y
Sbjct: 240 YLLIIRSLRQG--LRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVL-----HYRS 292
Query: 267 WGA-------------FTTFLMNLSTCLDVILYYIVSKQFQARVISVM 301
GA T+ L +L+ LD I+Y+ V+++F+ + +++
Sbjct: 293 HGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLL 340
>gi|241982708 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 137 bits (345), Expect = 1e-32
Identities = 95/335 (28%), Positives = 162/335 (48%), Gaps = 32/335 (9%)
Query: 11 VPFNSSH---PDEYKIAAL-VFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVAL 66
V NSSH D +K +S +F++GL N A+++F C K R T YM+N+A+
Sbjct: 2 VSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAM 61
Query: 67 VDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSI--ALWLLAFISADRYMAIV 124
DL+F+ TLPFR+FY+ WPFG+ C+I ++ +FY ++ ++ L IS DR++AIV
Sbjct: 62 SDLLFVFTLPFRIFYFTTRNWPFGDLLCKI--SVMLFYTNMYGSILFLTCISVDRFLAIV 119
Query: 125 QPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDK-DSTPATCLKISDIIYLKA 183
P +K L+ A + C GVW+ + + P + + + ++ C + + +A
Sbjct: 120 YPFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFE----NFPEA 175
Query: 184 VNVLNLTRLTFF-----FLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLL 238
L+R+ F F IPL + + C +++ L T K K +++I L
Sbjct: 176 TWKTYLSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHL 235
Query: 239 VQVLVCFMPFH---ICFAFLMLGTGENSYNPWGAFTTFLMNL-----STCLDVILYYIVS 290
+ CF+P++ I ++ + T N T + + L + C D I+YY S
Sbjct: 236 IIFCFCFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTS 295
Query: 291 KQFQARVISVMLYRNYLRSMRRKSFRSGSLRSLSN 325
Q + + +N+ S+RR FR + N
Sbjct: 296 DTIQ----NSIKMKNW--SVRRSDFRFSEVHGAEN 324
>gi|241982706 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 137 bits (345), Expect = 1e-32
Identities = 95/335 (28%), Positives = 162/335 (48%), Gaps = 32/335 (9%)
Query: 11 VPFNSSH---PDEYKIAAL-VFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVAL 66
V NSSH D +K +S +F++GL N A+++F C K R T YM+N+A+
Sbjct: 2 VSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAM 61
Query: 67 VDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSI--ALWLLAFISADRYMAIV 124
DL+F+ TLPFR+FY+ WPFG+ C+I ++ +FY ++ ++ L IS DR++AIV
Sbjct: 62 SDLLFVFTLPFRIFYFTTRNWPFGDLLCKI--SVMLFYTNMYGSILFLTCISVDRFLAIV 119
Query: 125 QPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDK-DSTPATCLKISDIIYLKA 183
P +K L+ A + C GVW+ + + P + + + ++ C + + +A
Sbjct: 120 YPFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFE----NFPEA 175
Query: 184 VNVLNLTRLTFF-----FLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLL 238
L+R+ F F IPL + + C +++ L T K K +++I L
Sbjct: 176 TWKTYLSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHL 235
Query: 239 VQVLVCFMPFH---ICFAFLMLGTGENSYNPWGAFTTFLMNL-----STCLDVILYYIVS 290
+ CF+P++ I ++ + T N T + + L + C D I+YY S
Sbjct: 236 IIFCFCFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTS 295
Query: 291 KQFQARVISVMLYRNYLRSMRRKSFRSGSLRSLSN 325
Q + + +N+ S+RR FR + N
Sbjct: 296 DTIQ----NSIKMKNW--SVRRSDFRFSEVHGAEN 324
>gi|33695113 G-protein coupled purinergic receptor P2Y5 [Homo
sapiens]
Length = 344
Score = 137 bits (345), Expect = 1e-32
Identities = 95/335 (28%), Positives = 162/335 (48%), Gaps = 32/335 (9%)
Query: 11 VPFNSSH---PDEYKIAAL-VFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVAL 66
V NSSH D +K +S +F++GL N A+++F C K R T YM+N+A+
Sbjct: 2 VSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAM 61
Query: 67 VDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSI--ALWLLAFISADRYMAIV 124
DL+F+ TLPFR+FY+ WPFG+ C+I ++ +FY ++ ++ L IS DR++AIV
Sbjct: 62 SDLLFVFTLPFRIFYFTTRNWPFGDLLCKI--SVMLFYTNMYGSILFLTCISVDRFLAIV 119
Query: 125 QPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDK-DSTPATCLKISDIIYLKA 183
P +K L+ A + C GVW+ + + P + + + ++ C + + +A
Sbjct: 120 YPFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFE----NFPEA 175
Query: 184 VNVLNLTRLTFF-----FLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLL 238
L+R+ F F IPL + + C +++ L T K K +++I L
Sbjct: 176 TWKTYLSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRSKINKTKVLKMIFVHL 235
Query: 239 VQVLVCFMPFH---ICFAFLMLGTGENSYNPWGAFTTFLMNL-----STCLDVILYYIVS 290
+ CF+P++ I ++ + T N T + + L + C D I+YY S
Sbjct: 236 IIFCFCFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTS 295
Query: 291 KQFQARVISVMLYRNYLRSMRRKSFRSGSLRSLSN 325
Q + + +N+ S+RR FR + N
Sbjct: 296 DTIQ----NSIKMKNW--SVRRSDFRFSEVHGAEN 324
>gi|4885311 lysophosphatidic acid receptor 4 [Homo sapiens]
Length = 370
Score = 131 bits (329), Expect = 1e-30
Identities = 83/281 (29%), Positives = 142/281 (50%), Gaps = 22/281 (7%)
Query: 29 YSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWP 88
YS +FI+GL N +L+VF K R+ I++ N+A+ DL+F+ TLPF++FY WP
Sbjct: 46 YSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRHWP 105
Query: 89 FGEYFCQILGALTVFYPSI--ALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVW 146
FG+ C+I G T F +I ++ L IS DR++AIV P ++ ++ + + C GVW
Sbjct: 106 FGDTLCKISG--TAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVW 163
Query: 147 IMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFF-----FLIPLF 201
I+ L+ L+ + ++ TC + + K V L+++T F F+IPL
Sbjct: 164 ILVLSGGIS-ASLFSTTNVNNATTTCFE----GFSKRVWKTYLSKITIFIEVVGFIIPLI 218
Query: 202 IMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFH-ICFAFLMLGTG 260
+ + C V++ L T K+K +++I + +VCF+P++ + F + ++ +
Sbjct: 219 LNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQ 278
Query: 261 -------ENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQ 294
E T L L+ C D +YY + FQ
Sbjct: 279 AITNCFLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQ 319
>gi|148225857 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 131 bits (329), Expect = 1e-30
Identities = 100/342 (29%), Positives = 171/342 (50%), Gaps = 35/342 (10%)
Query: 5 NNQDQP------VPFNSSHPDEYKIAALVF---YSCIFIIGLFVNITALWVFSCTTKKRT 55
N+ DQP P ++ P + K+ + V YS IFI+GL NI AL+VF +KR
Sbjct: 28 NHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRN 87
Query: 56 TVTIYMMNVALVDLIFIMTLPFRMFYYA-KDEWPFGEYFCQILGALTVFYPSIALWLLAF 114
++ IY++NVA+ DL+ I LPFR+ Y+ +++W G C+++G L I++ LL F
Sbjct: 88 SIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGF 147
Query: 115 ISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTL-TTTTPLLLLYKDPDKDSTPATCL 173
IS DRY+ I + ++ T +++ C VW++ L T ++L K +ST C
Sbjct: 148 ISLDRYIKINRSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNST--MCF 205
Query: 174 KISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEK---- 229
D K + N + F+LI L I++ Y+ I NLL R SK + K
Sbjct: 206 HYRDKHNAKGEAIFNFILVVMFWLIFLLIILS-YIKIGKNLL--RISKRRSKFPNSGKYA 262
Query: 230 -SIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNPW--------GAFTTFLMNLSTC 280
+ R +L+ +CF+P+H F F+ + + N + + L + ++C
Sbjct: 263 TTARNSFIVLIIFTICFVPYH-AFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSC 321
Query: 281 LDVILYYIVSKQFQARVISVMLYRNY----LRSMRRKSFRSG 318
LD ++Y+++S + +++ +L+R + RS F+ G
Sbjct: 322 LDPVMYFLMSSNIR-KIMCQLLFRRFQGEPSRSESTSEFKPG 362
>gi|4885319 G protein-coupled receptor 34 [Homo sapiens]
Length = 381
Score = 131 bits (329), Expect = 1e-30
Identities = 100/342 (29%), Positives = 171/342 (50%), Gaps = 35/342 (10%)
Query: 5 NNQDQP------VPFNSSHPDEYKIAALVF---YSCIFIIGLFVNITALWVFSCTTKKRT 55
N+ DQP P ++ P + K+ + V YS IFI+GL NI AL+VF +KR
Sbjct: 28 NHSDQPPQNFSATPNVTTCPMDEKLLSTVLTTSYSVIFIVGLVGNIIALYVFLGIHRKRN 87
Query: 56 TVTIYMMNVALVDLIFIMTLPFRMFYYA-KDEWPFGEYFCQILGALTVFYPSIALWLLAF 114
++ IY++NVA+ DL+ I LPFR+ Y+ +++W G C+++G L I++ LL F
Sbjct: 88 SIQIYLLNVAIADLLLIFCLPFRIMYHINQNKWTLGVILCKVVGTLFYMNMYISIILLGF 147
Query: 115 ISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTL-TTTTPLLLLYKDPDKDSTPATCL 173
IS DRY+ I + ++ T +++ C VW++ L T ++L K +ST C
Sbjct: 148 ISLDRYIKINRSIQQRKAITTKQSIYVCCIVWMLALGGFLTMIILTLKKGGHNST--MCF 205
Query: 174 KISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEK---- 229
D K + N + F+LI L I++ Y+ I NLL R SK + K
Sbjct: 206 HYRDKHNAKGEAIFNFILVVMFWLIFLLIILS-YIKIGKNLL--RISKRRSKFPNSGKYA 262
Query: 230 -SIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNPW--------GAFTTFLMNLSTC 280
+ R +L+ +CF+P+H F F+ + + N + + L + ++C
Sbjct: 263 TTARNSFIVLIIFTICFVPYH-AFRFIYISSQLNVSSCYWKEIVHKTNEIMLVLSSFNSC 321
Query: 281 LDVILYYIVSKQFQARVISVMLYRNY----LRSMRRKSFRSG 318
LD ++Y+++S + +++ +L+R + RS F+ G
Sbjct: 322 LDPVMYFLMSSNIR-KIMCQLLFRRFQGEPSRSESTSEFKPG 362
>gi|52426789 oxoglutarate (alpha-ketoglutarate) receptor 1 [Homo
sapiens]
Length = 337
Score = 129 bits (323), Expect = 5e-30
Identities = 86/283 (30%), Positives = 136/283 (48%), Gaps = 11/283 (3%)
Query: 27 VFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDE 86
V Y IF++G N + + + + TI M+N+A DL+++ +LPF + YYA E
Sbjct: 38 VIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGE 97
Query: 87 -WPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGV 145
W FG++ C+ + F ++ L S RY I+ P + T AV+AC V
Sbjct: 98 NWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVV 157
Query: 146 WIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIG 205
WI++L P+ L ++ + A CL ++ L + NL F +PL I+
Sbjct: 158 WIISLVAVIPMTFLITSTNRTNRSA-CLDLTSSDELNTIKWYNLILTATTFCLPLVIVTL 216
Query: 206 CYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLG------- 258
CY IIH L HG + +K+K+ R+ I LL+ VCF+PFHI +
Sbjct: 217 CYTTIIHTLTHG--LQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRLLSISC 274
Query: 259 TGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVM 301
+ EN + + L L+T +++LY +VS FQ V S +
Sbjct: 275 SIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTV 317
>gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens]
Length = 361
Score = 127 bits (319), Expect = 1e-29
Identities = 82/302 (27%), Positives = 148/302 (49%), Gaps = 19/302 (6%)
Query: 16 SHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTL 75
+H +I + YS +FIIGL N+ AL V KK + T+Y N+ + D++F L
Sbjct: 25 AHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTAL 84
Query: 76 PFRMFYYAKD-EWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKN 134
P R+ YYA +W G+ C+I + + + +S DR++A+V P ++K
Sbjct: 85 PTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKR 144
Query: 135 TCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTF 194
A C+ VWI+ T P LL+ +++ TC++ + K++ + L
Sbjct: 145 IEHAKGVCIFVWILVFAQTLP-LLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFI 203
Query: 195 FFLIPLFIMIGCYLVIIHNLLHGRTSKLKP-----KVKEKSIRIIITLLVQVLVCFMPFH 249
+++PL I++ CY I L RT+K P V +K++ II ++V ++CF P+H
Sbjct: 204 GYVLPLIIILICYSQICCKLF--RTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYH 261
Query: 250 IC----------FAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVIS 299
+ F+ + + +S+ FT LMN + C+D +Y+ K ++ +V+
Sbjct: 262 VAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMR 321
Query: 300 VM 301
++
Sbjct: 322 ML 323
>gi|4505557 purinergic receptor P2Y1 [Homo sapiens]
Length = 373
Score = 123 bits (309), Expect = 2e-28
Identities = 81/315 (25%), Positives = 151/315 (47%), Gaps = 33/315 (10%)
Query: 29 YSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYY-AKDEW 87
Y +FIIG N A+W+F K + +++YM N+AL D ++++TLP +FYY K +W
Sbjct: 58 YILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDW 117
Query: 88 PFGEYFCQILGALTVFYPSI--ALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGV 145
FG+ C++ +F+ ++ ++ L ISA RY +V P + A+ V V
Sbjct: 118 IFGDAMCKL--QRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLV 175
Query: 146 WIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIG 205
W++ + +P+L + + TC + YL++ + ++ F +PL +++G
Sbjct: 176 WLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILG 235
Query: 206 CYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAF----------- 254
CY +I+ L++ ++ KSI ++I +L V ++PFH+
Sbjct: 236 CYGLIVRALIYKDLD--NSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTP 293
Query: 255 LMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRNYLRSMRRKS 314
M + Y + T L +L++C+D ILY++ F+ R+ ++
Sbjct: 294 AMCAFNDRVYATY-QVTRGLASLNSCVDPILYFLAGDTFRRRL--------------SRA 338
Query: 315 FRSGSLRSLSNINSE 329
R S RS +N+ S+
Sbjct: 339 TRKASRRSEANLQSK 353
>gi|4885121 chemokine (C-C motif) receptor 8 [Homo sapiens]
Length = 355
Score = 120 bits (301), Expect = 2e-27
Identities = 78/312 (25%), Positives = 145/312 (46%), Gaps = 21/312 (6%)
Query: 22 KIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFY 81
K+ VFY +F+ L N + V K R+ +Y++N+AL DL+F+ + PF+ Y
Sbjct: 35 KLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQT-Y 93
Query: 82 YAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLA 141
Y D+W FG C+++ +++ + +S DRY+A+V YA +++
Sbjct: 94 YLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTL 153
Query: 142 CVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLF 201
C+ VW+ + T PLL+ Y+ +D C + LK N LIP
Sbjct: 154 CLAVWLTAIMATIPLLVFYQVASEDGV-LQCYSFYNQQTLKWKIFTNFKMNILGLLIPFT 212
Query: 202 IMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLML---- 257
I + CY+ I+H L + + K K+IR+++ +++ L+ ++PF++ L
Sbjct: 213 IFMFCYIKILHQL-----KRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMH 267
Query: 258 ---GTGENSYNPWGAFTTFLMNLS-TCLDVILYYIVSKQFQARVISVMLYR-----NYL- 307
G + + T +++ + C++ ++Y V ++F+ + + NYL
Sbjct: 268 ILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLG 327
Query: 308 RSMRRKSFRSGS 319
R M R+S S
Sbjct: 328 RQMPRESCEKSS 339
>gi|9966851 cysteinyl leukotriene receptor 2 [Homo sapiens]
Length = 346
Score = 119 bits (298), Expect = 4e-27
Identities = 75/281 (26%), Positives = 143/281 (50%), Gaps = 9/281 (3%)
Query: 27 VFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAK-D 85
+ Y IF G+ N +++VF KK T+V ++M+N+A+ DL+FI TLPFR YY +
Sbjct: 43 IVYLIIFFWGVLGNGLSIYVFLQPYKKSTSVNVFMLNLAISDLLFISTLPFRADYYLRGS 102
Query: 86 EWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGV 145
W FG+ C+I+ +++ L +S R++A+V P + + A + C +
Sbjct: 103 NWIFGDLACRIMSYSLYVNMYSSIYFLTVLSVVRFLAMVHPFRLLHVTSIRSAWILCGII 162
Query: 146 WIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIG 205
WI+ + ++ ++LL +++ + +CL++ ++ + + +N L L+P F +
Sbjct: 163 WILIMASS--IMLLDSGSEQNGSVTSCLEL-NLYKIAKLQTMNYIALVVGCLLPFFTLSI 219
Query: 206 CYLVIIHNLLHGRTSKLKPKVK-EKSIRIIITLLVQVLVCFMPFH----ICFAFLMLGTG 260
CYL+II LL + +V K++ II L+ +CF+P+H + +G
Sbjct: 220 CYLLIIRVLLKVEVPESGLRVSHRKALTTIIITLIIFFLCFLPYHTLRTVHLTTWKVGLC 279
Query: 261 ENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVM 301
++ + T L + C + +LYY + F+ R+ S +
Sbjct: 280 KDRLHKALVITLALAAANACFNPLLYYFAGENFKDRLKSAL 320
>gi|34577052 coagulation factor II (thrombin) receptor-like 1
precursor [Homo sapiens]
Length = 397
Score = 117 bits (294), Expect = 1e-26
Identities = 77/288 (26%), Positives = 140/288 (48%), Gaps = 13/288 (4%)
Query: 27 VFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAK-D 85
+ Y+ +F++GL N ALWVF TKK+ IYM N+AL DL+ ++ P ++ Y+ +
Sbjct: 80 IVYTIVFVVGLPSNGMALWVFLFRTKKKHPAVIYMANLALADLLSVIWFPLKIAYHIHGN 139
Query: 86 EWPFGEYFCQILGALTVFYPSI--ALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACV 143
W +GE C +L + FY ++ ++ + +S RY IV P K A+ +
Sbjct: 140 NWIYGEALCNVL--IGFFYGNMYCSILFMTCLSVQRYWVIVNP-MGHSRKKANIAIGISL 196
Query: 144 GVWIMTLTTTTPLLLLYKD---PDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPL 200
+W++ L T PL ++ + P + T + ++ N L+ FL P
Sbjct: 197 AIWLLILLVTIPLYVVKQTIFIPALNITTCHDVLPEQLLVGDMFNYF-LSLAIGVFLFPA 255
Query: 201 FIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFA---FLML 257
F+ Y+++I L + K ++++I++I+T+L L+CF P ++ FL+
Sbjct: 256 FLTASAYVLMIRMLRSSAMDENSEKKRKRAIKLIVTVLAMYLICFTPSNLLLVVHYFLIK 315
Query: 258 GTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRN 305
G++ L L++C+D +YY VS F+ + +L R+
Sbjct: 316 SQGQSHVYALYIVALCLSTLNSCIDPFVYYFVSHDFRDHAKNALLCRS 363
>gi|4885057 apelin receptor [Homo sapiens]
Length = 380
Score = 115 bits (289), Expect = 4e-26
Identities = 79/294 (26%), Positives = 144/294 (48%), Gaps = 25/294 (8%)
Query: 29 YSCIFIIGLFVNITALW-VFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKD-E 86
Y +F++G N LW VF + +KR + I++ ++A+ DL F++TLP Y +D +
Sbjct: 35 YMLVFLLGTTGNGLVLWTVFRSSREKRRSADIFIASLAVADLTFVVTLPLWATYTYRDYD 94
Query: 87 WPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVW 146
WPFG +FC++ L +++ L +S DRY+AIV+P L+ +A +W
Sbjct: 95 WPFGTFFCKLSSYLIFVNMYASVFCLTGLSFDRYLAIVRPVANARLRLRVSGAVATAVLW 154
Query: 147 IMTLTTTTPLLLLYKDPD-KDSTPATCLKISDIIYLKAVN-----VLNLTRLTFFFLIPL 200
++ P+++L D +++T C ++ + L ++ T F++P
Sbjct: 155 VLAALLAMPVMVLRTTGDLENTTKVQCYMDYSMVATVSSEWAWEVGLGVSSTTVGFVVPF 214
Query: 201 FIMIGCYLVIIHNLL-HGRTSKLKP-KVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLG 258
IM+ CY I + H R +++ + + + + II+ L+V +C+MP+H+ MLG
Sbjct: 215 TIMLTCYFFIAQTIAGHFRKERIEGLRKRRRLLSIIVVLVVTFALCWMPYHLVKTLYMLG 274
Query: 259 TGENSYNPWGA-FTTFLMNL----------STCLDVILYYIVSKQFQARVISVM 301
S W F FLMN+ ++CL+ LY +F+ S++
Sbjct: 275 ----SLLHWPCDFDLFLMNIFPYCTCISYVNSCLNPFLYAFFDPRFRQACTSML 324
>gi|5729798 cysteinyl leukotriene receptor 1 [Homo sapiens]
Length = 337
Score = 115 bits (288), Expect = 5e-26
Identities = 83/279 (29%), Positives = 131/279 (46%), Gaps = 12/279 (4%)
Query: 29 YSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYA-KDEW 87
YS I ++G F N L+V T K++ +YM+N+A+ DL+ + TLP R+ YY K W
Sbjct: 30 YSMISVVGFFGNGFVLYVLIKTYHKKSAFQVYMINLAVADLLCVCTLPLRVVYYVHKGIW 89
Query: 88 PFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWI 147
FG++ C++ +++ + +S R +AIV P L KA CVG+WI
Sbjct: 90 LFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVFPVQNINLVTQKKARFVCVGIWI 149
Query: 148 MTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCY 207
+ T++P L+ D+ + D V VL+ L F+IP I+I CY
Sbjct: 150 FVILTSSPFLMAKPQKDEKNNTKCFEPPQDNQTKNHVLVLHYVSLFVGFIIPFVIIIVCY 209
Query: 208 LVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNPW 267
+II LL ++ K +K+I +I+ + LV FMP+HI + L N P
Sbjct: 210 TMIILTLLK-KSMKKNLSSHKKAIGMIMVVTAAFLVSFMPYHI-QRTIHLHFLHNETKPC 267
Query: 268 GA---------FTTFLMNLSTCLDVILYYIVSKQFQARV 297
+ T L + C D +LY+ F+ R+
Sbjct: 268 DSVLRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRKRL 306
>gi|219281887 lysophosphatidic acid receptor 5 [Homo sapiens]
Length = 372
Score = 114 bits (285), Expect = 1e-25
Identities = 72/232 (31%), Positives = 115/232 (49%), Gaps = 6/232 (2%)
Query: 26 LVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKD 85
LV YS + GL +N ALWVF + + V++YM N+A DL+F ++LP R+ YYA
Sbjct: 26 LVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALH 85
Query: 86 EWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGV 145
WPF + CQ GA+ + L I+ DRY AIV P + L+ A L C+GV
Sbjct: 86 HWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGV 145
Query: 146 WIMTLTTTTPLLLLYKDPD---KDSTPATCLK-ISDIIYLKAVNVLNLTRLTFFFLIPLF 201
W + L P +++ +D C + SD ++ + L L FL+PL
Sbjct: 146 WALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLA 205
Query: 202 IMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFA 253
++ + L R + + + K++R+++ LV L+CF+P++ A
Sbjct: 206 AVVYSSGRVFWTL--ARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLA 255
>gi|9966879 lysophosphatidic acid receptor 5 [Homo sapiens]
Length = 372
Score = 114 bits (285), Expect = 1e-25
Identities = 72/232 (31%), Positives = 115/232 (49%), Gaps = 6/232 (2%)
Query: 26 LVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKD 85
LV YS + GL +N ALWVF + + V++YM N+A DL+F ++LP R+ YYA
Sbjct: 26 LVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALH 85
Query: 86 EWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGV 145
WPF + CQ GA+ + L I+ DRY AIV P + L+ A L C+GV
Sbjct: 86 HWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGV 145
Query: 146 WIMTLTTTTPLLLLYKDPD---KDSTPATCLK-ISDIIYLKAVNVLNLTRLTFFFLIPLF 201
W + L P +++ +D C + SD ++ + L L FL+PL
Sbjct: 146 WALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLA 205
Query: 202 IMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFA 253
++ + L R + + + K++R+++ LV L+CF+P++ A
Sbjct: 206 AVVYSSGRVFWTL--ARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLA 255
>gi|37187860 chemokine (C-C motif) receptor 6 [Homo sapiens]
Length = 374
Score = 113 bits (283), Expect = 2e-25
Identities = 84/305 (27%), Positives = 144/305 (47%), Gaps = 23/305 (7%)
Query: 27 VFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDE 86
+ YS I + GL NI + F+ K R+ +Y++N+A+ D++F++TLPF +A
Sbjct: 51 IAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGA 110
Query: 87 WPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTC--KAVLACVG 144
W F C++L + + + LL IS DRY+AIVQ + L++ ++ + C+
Sbjct: 111 WVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLV 170
Query: 145 VWIMTLTTTTPLLLL---YKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLF 201
VW +++ ++ + Y D +S+ I K + +L L L F F IPL
Sbjct: 171 VWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLL-MLGL-ELLFGFFIPLM 228
Query: 202 IMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTG- 260
MI CY I+ L+ + SK + K+IR+II +++ L C +P ++ G
Sbjct: 229 FMIFCYTFIVKTLVQAQNSK-----RHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGK 283
Query: 261 -------ENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRNYLRSMRRK 313
E T L L CL+ +LY + ++F+ + ++ L +RRK
Sbjct: 284 MNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKIL---KDLWCVRRK 340
Query: 314 SFRSG 318
SG
Sbjct: 341 YKSSG 345
>gi|37188165 chemokine (C-C motif) receptor 6 [Homo sapiens]
Length = 374
Score = 113 bits (283), Expect = 2e-25
Identities = 84/305 (27%), Positives = 144/305 (47%), Gaps = 23/305 (7%)
Query: 27 VFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDE 86
+ YS I + GL NI + F+ K R+ +Y++N+A+ D++F++TLPF +A
Sbjct: 51 IAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGA 110
Query: 87 WPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTC--KAVLACVG 144
W F C++L + + + LL IS DRY+AIVQ + L++ ++ + C+
Sbjct: 111 WVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLV 170
Query: 145 VWIMTLTTTTPLLLL---YKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLF 201
VW +++ ++ + Y D +S+ I K + +L L L F F IPL
Sbjct: 171 VWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLL-MLGL-ELLFGFFIPLM 228
Query: 202 IMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTG- 260
MI CY I+ L+ + SK + K+IR+II +++ L C +P ++ G
Sbjct: 229 FMIFCYTFIVKTLVQAQNSK-----RHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGK 283
Query: 261 -------ENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRNYLRSMRRK 313
E T L L CL+ +LY + ++F+ + ++ L +RRK
Sbjct: 284 MNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKIL---KDLWCVRRK 340
Query: 314 SFRSG 318
SG
Sbjct: 341 YKSSG 345
>gi|4502641 chemokine (C-C motif) receptor 7 precursor [Homo
sapiens]
Length = 378
Score = 113 bits (283), Expect = 2e-25
Identities = 72/227 (31%), Positives = 122/227 (53%), Gaps = 13/227 (5%)
Query: 27 VFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDE 86
+ YS I +GL N + + + +T Y++N+A+ D++F++TLPF Y A
Sbjct: 63 IMYSIICFVGLLGNGLVVLTYIYFKRLKTMTDTYLLNLAVADILFLLTLPF-WAYSAAKS 121
Query: 87 WPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAV--LACVG 144
W FG +FC+++ A+ + LL IS DRY+AIVQ A + + L+CVG
Sbjct: 122 WVFGVHFCKLIFAIYKMSFFSGMLLLLCISIDRYVAIVQAVSAHRHRARVLLISKLSCVG 181
Query: 145 VWIMTLTTTTPLLLLYKDPDKDSTPAT--CLKISDIIYLKAVNVLNLTRLTFFFLIPLFI 202
+WI+ + P LLY D + S+ C I++ +++A + + ++ FL+PL
Sbjct: 182 IWILATVLSIP-ELLYSDLQRSSSEQAMRCSLITE--HVEAFITIQVAQMVIGFLVPLLA 238
Query: 203 MIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFH 249
M CYLVII LL R + + K+I++II ++V +V +P++
Sbjct: 239 MSFCYLVIIRTLLQARNFE-----RNKAIKVIIAVVVVFIVFQLPYN 280
>gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo
sapiens]
Length = 359
Score = 113 bits (283), Expect = 2e-25
Identities = 91/330 (27%), Positives = 159/330 (48%), Gaps = 34/330 (10%)
Query: 23 IAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYY 82
+A V YS + + + N+ +LWV R+ I+M+N+++ DL+ LPF+++Y+
Sbjct: 24 VALPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTDLMLASVLPFQIYYH 83
Query: 83 A-KDEWPFGEYFCQILGALTVFYPSI--ALWLLAFISADRYMAIVQPKYAKELKNTCKAV 139
+ W FG C ++ FY ++ ++ + IS +R++ ++ P +K + AV
Sbjct: 84 CNRHHWVFGVLLCNVV--TVAFYANMYSSILTMTCISVERFLGVLYPLSSKRWRRRRYAV 141
Query: 140 LACVGVWIMTLTTTTPLL---LLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFF- 195
AC G W++ LT +PL L Y P TC + L +V + + T F
Sbjct: 142 AACAGTWLLLLTALSPLARTDLTY--PVHALGIITCFDVLKWTMLPSVAMWAVFLFTIFI 199
Query: 196 --FLIPLFIMIGCYLVIIHNLL-----HGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPF 248
FLIP I + CY I LL HGR + + +++ + +L+ + CF P
Sbjct: 200 LLFLIPFVITVACYTATILKLLRTEEAHGR------EQRRRAVGLAAVVLLAFVTCFAPN 253
Query: 249 H-ICFAFLM--LGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRN 305
+ + A ++ L G++ Y+ + T L L+ CLD +YY S++FQ R+ + R
Sbjct: 254 NFVLLAHIVSRLFYGKSYYHVY-KLTLCLSCLNNCLDPFVYYFASREFQLRLREYLGCRR 312
Query: 306 YLR---SMRRKSF---RSGSLRSLSNINSE 329
R RR+S R+ S+RS + + E
Sbjct: 313 VPRDTLDTRRESLFSARTTSVRSEAGAHPE 342
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 112 bits (280), Expect = 5e-25
Identities = 70/273 (25%), Positives = 134/273 (49%), Gaps = 7/273 (2%)
Query: 29 YSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWP 88
YS +F++GL N ++V TK +T IY+ N+AL D + T+PF+ Y + WP
Sbjct: 66 YSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWP 125
Query: 89 FGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWIM 148
FG+ C+I+ ++ + +++ L +S DRY+A+ P A + + KA + + +W++
Sbjct: 126 FGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLL 185
Query: 149 TLTTTTPLLLLYKDPDKDSTPA--TCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGC 206
+ + ++L ++ L+ D Y + + F F+IP+ I+I C
Sbjct: 186 SSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVC 245
Query: 207 YLVIIHNLLHGRT---SKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENS 263
Y ++I L R S+ K + + R+++ ++ +VC+ P HI LG+ +S
Sbjct: 246 YTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHS 305
Query: 264 YNPWGA--FTTFLMNLSTCLDVILYYIVSKQFQ 294
+ F L ++ L+ ILY + + F+
Sbjct: 306 TAALSSYYFCIALGYTNSSLNPILYAFLDENFK 338
>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
Length = 493
Score = 112 bits (279), Expect = 6e-25
Identities = 78/297 (26%), Positives = 138/297 (46%), Gaps = 8/297 (2%)
Query: 4 LNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMN 63
L +D P S I + YS + ++GLF N ++V TK +T IY+ N
Sbjct: 145 LGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFN 204
Query: 64 VALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAI 123
+AL D + TLPF+ Y WPFG C+I+ ++ + +++ L +S DRY+A+
Sbjct: 205 LALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAV 264
Query: 124 VQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKA 183
P A + + A + V WI++ P++ + + + L S +
Sbjct: 265 CHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWE 324
Query: 184 VNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRT---SKLKPKVKEKSIRIIITLLVQ 240
N+L + F F++P+ I+ CY ++I L R SK K + + R+++ ++
Sbjct: 325 -NLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAV 383
Query: 241 VLVCFMPFHICFAFLMLGT-GENSYN--PWGAFTTFLMNLSTCLDVILYYIVSKQFQ 294
+VC+ P HI L T E ++ W F L ++CL+ +LY + + F+
Sbjct: 384 FIVCWTPIHIYVIIKALVTIPETTFQTVSW-HFCIALGYTNSCLNPVLYAFLDENFK 439
>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
Length = 400
Score = 112 bits (279), Expect = 6e-25
Identities = 78/297 (26%), Positives = 138/297 (46%), Gaps = 8/297 (2%)
Query: 4 LNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMN 63
L +D P S I + YS + ++GLF N ++V TK +T IY+ N
Sbjct: 52 LGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFN 111
Query: 64 VALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAI 123
+AL D + TLPF+ Y WPFG C+I+ ++ + +++ L +S DRY+A+
Sbjct: 112 LALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAV 171
Query: 124 VQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKA 183
P A + + A + V WI++ P++ + + + L S +
Sbjct: 172 CHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWE 231
Query: 184 VNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRT---SKLKPKVKEKSIRIIITLLVQ 240
N+L + F F++P+ I+ CY ++I L R SK K + + R+++ ++
Sbjct: 232 -NLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAV 290
Query: 241 VLVCFMPFHICFAFLMLGT-GENSYN--PWGAFTTFLMNLSTCLDVILYYIVSKQFQ 294
+VC+ P HI L T E ++ W F L ++CL+ +LY + + F+
Sbjct: 291 FIVCWTPIHIYVIIKALVTIPETTFQTVSW-HFCIALGYTNSCLNPVLYAFLDENFK 346
>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
Length = 420
Score = 112 bits (279), Expect = 6e-25
Identities = 78/297 (26%), Positives = 138/297 (46%), Gaps = 8/297 (2%)
Query: 4 LNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMN 63
L +D P S I + YS + ++GLF N ++V TK +T IY+ N
Sbjct: 52 LGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFN 111
Query: 64 VALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAI 123
+AL D + TLPF+ Y WPFG C+I+ ++ + +++ L +S DRY+A+
Sbjct: 112 LALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAV 171
Query: 124 VQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKA 183
P A + + A + V WI++ P++ + + + L S +
Sbjct: 172 CHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWE 231
Query: 184 VNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRT---SKLKPKVKEKSIRIIITLLVQ 240
N+L + F F++P+ I+ CY ++I L R SK K + + R+++ ++
Sbjct: 232 -NLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAV 290
Query: 241 VLVCFMPFHICFAFLMLGT-GENSYN--PWGAFTTFLMNLSTCLDVILYYIVSKQFQ 294
+VC+ P HI L T E ++ W F L ++CL+ +LY + + F+
Sbjct: 291 FIVCWTPIHIYVIIKALVTIPETTFQTVSW-HFCIALGYTNSCLNPVLYAFLDENFK 346
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.331 0.142 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,041,991
Number of Sequences: 37866
Number of extensions: 426429
Number of successful extensions: 2254
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 299
Number of HSP's successfully gapped in prelim test: 225
Number of HSP's that attempted gapping in prelim test: 1315
Number of HSP's gapped (non-prelim): 578
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.